# RGD-PIPELINE: ftp-file-extracts # MODULE: annotations-version-1.1.9 (Oct 10, 2019) # GENERATED-ON: 2025/02/01 # PURPOSE: annotations about active Pig objects extracted from RGD database # ONTOLOGY: ChEBI: ChEBI Ontology # CONTACT: rgd.data@mcw.edu # FORMAT: tab delimited text # NOTES: multiple values in a single column are separated by '|' # #COLUMN INFORMATION: # #1 RGD_ID unique RGD_ID of the annotated object #2 OBJECT_SYMBOL official symbol of the annotated object #3 OBJECT_NAME official name of the annotated object #4 OBJECT_TYPE annotated object data type: one of ['gene','qtl','strain'] #5 TERM_ACC_ID ontology term accession id #6 TERM_NAME ontology term name #7 QUALIFIER optional qualifier #8 EVIDENCE evidence #9 WITH with info #10 ASPECT aspect #11 REFERENCES db references (Reference RGDID|PUBMED ID) #12 CREATED_DATE created date #13 ASSIGNED_BY assigned by #14 MESH_OMIM_ID MESH:xxx or OMIM:xxx id corresponding to RDO:xxx id found in TERM_ACC_ID column (RGD/CTD Disease Ontology annotations only) #15 CURATION_NOTES curation notes provided by RGD curators #16 ORIGINAL_REFERENCE original reference RGD_ID OBJECT_SYMBOL OBJECT_NAME OBJECT_TYPE TERM_ACC_ID TERM_NAME QUALIFIER EVIDENCE WITH ASPECT REFERENCES CREATED_DATE ASSIGNED_BY MESH_OMIM_ID CURATION_NOTES ORIGINAL_REFERENCE 13842626 CXCR2 C-X-C motif chemokine receptor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CXCR2 mRNA PMID:35307453 13842626 CXCR2 C-X-C motif chemokine receptor 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of CXCR2 mRNA; Zearalenone results in increased expression of CXCR2 protein PMID:29758222 13842626 CXCR2 C-X-C motif chemokine receptor 2 gene CHEBI:15553 prostaglandin F2alpha increases expression EXP E RGD:6480464 20191114 CTD MESH:D015237 Dinoprost results in increased expression of CXCR2 mRNA PMID:21505051 13842626 CXCR2 C-X-C motif chemokine receptor 2 gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015237 epostane promotes the reaction [Dinoprost results in increased expression of CXCR2 mRNA] PMID:21505051 13842693 IL1B2 interleukin 1, beta 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of IL1B2 mRNA PMID:27915442 13842693 IL1B2 interleukin 1, beta 2 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1B2 mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1B2 mRNA] PMID:27915442 13842693 IL1B2 interleukin 1, beta 2 gene CHEBI:7599 Nivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C038405 nivalenol results in increased expression of IL1B2 mRNA PMID:27915442 13842693 IL1B2 interleukin 1, beta 2 gene CHEBI:7599 Nivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C038405 deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1B2 mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1B2 mRNA] PMID:27915442 13842714 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPWD1 mRNA PMID:35307453 13842752 TINAG tubulointerstitial nephritis antigen gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TINAG mRNA PMID:35307453 13842914 AUTS2 activator of transcription and developmental regulator AUTS2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of AUTS2 mRNA PMID:34933075 13842957 EDAR ectodysplasin A receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EDAR mRNA PMID:35307453 13842986 TTC9 tetratricopeptide repeat domain 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TTC9 mRNA PMID:35307453 13843161 CYB5A cytochrome b5 type A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYB5A mRNA PMID:35307453 13843179 PSMC4 proteasome 26S subunit, ATPase 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMC4 mRNA PMID:35307453 13843268 SST somatostatin gene CHEBI:23414 copper(II) sulfate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019327 Copper Sulfate results in decreased expression of SST mRNA; Copper Sulfate results in decreased expression of SST protein PMID:21110139 13843302 RUNDC1 RUN domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RUNDC1 mRNA PMID:35307453 13843313 C6H19orf81 chromosome 6 C19orf81 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C6H19ORF81 mRNA PMID:35307453 13843388 ULK4 unc-51 like kinase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ULK4 mRNA PMID:35307453 13843466 PRKCG protein kinase C gamma gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRKCG mRNA PMID:35307453 13843581 RAC2 Rac family small GTPase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAC2 mRNA PMID:35307453 13843649 TRIM45 tripartite motif containing 45 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRIM45 mRNA PMID:35307453 13843693 GPN1 GPN-loop GTPase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GPN1 mRNA PMID:35307453 13843726 FMO3 flavin containing dimethylaniline monoxygenase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FMO3 mRNA PMID:35307453 13843742 IGSF5 immunoglobulin superfamily member 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IGSF5 mRNA PMID:35307453 13843742 IGSF5 immunoglobulin superfamily member 5 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of IGSF5 mRNA PMID:34933075 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DDIT3 mRNA PMID:35307453 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of DDIT3 mRNA; deoxynivalenol results in increased expression of DDIT3 protein PMID:37442268|PMID:38608924 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 GSK2656157 inhibits the reaction [deoxynivalenol results in increased expression of DDIT3 protein]; Selenium analog inhibits the reaction [deoxynivalenol results in increased expression of DDIT3 protein] PMID:37442268 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:136004 linsidomine increases expression EXP E RGD:6480464 20191114 CTD MESH:C002385 linsidomine results in increased expression of DDIT3 mRNA PMID:18086661 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:139047 GSK2656157 multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C000597302 GSK2656157 inhibits the reaction [deoxynivalenol results in increased expression of DDIT3 protein] PMID:37442268 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:146195 3-acetyldeoxynivalenol increases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in increased expression of DDIT3 protein PMID:37659622 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:146195 3-acetyldeoxynivalenol multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C043247 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of DDIT3 protein] PMID:37659622 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA] PMID:36584959 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20231031 CTD MESH:D002104 Cadmium results in increased expression of DDIT3 mRNA PMID:37207789 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 protein; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of DDIT3 mRNA] PMID:33891997|PMID:37207789 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased expression of DDIT3 protein] PMID:37442268 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of DDIT3 mRNA PMID:36584959 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA] PMID:36584959 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA] PMID:18086661 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:29865 benzo[a]pyrene increases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in increased expression of DDIT3 protein PMID:36754226 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D001564 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of DDIT3 protein] PMID:36754226 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:3093 bifenthrin increases expression EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin results in increased expression of DDIT3 protein PMID:33901951 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of DDIT3 mRNA; bisphenol A results in increased expression of DDIT3 protein PMID:37108405|PMID:38845341 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of DDIT3 mRNA] PMID:37108405|PMID:38845341 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased expression of DDIT3 mRNA PMID:17464326|PMID:18086661 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 protein; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA] PMID:17464326|PMID:18086661|PMID:33891997 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased expression of DDIT3 protein] PMID:37442268 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:41500 4-phenylbutyric acid multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C075773 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of DDIT3 protein] PMID:36754226 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D018038 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein] PMID:37108405 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:49662 indometacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D007213 Indomethacin results in increased expression of DDIT3 mRNA PMID:18799549 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:64163 diquat increases expression EXP E RGD:6480464 20240903 CTD MESH:D004178 Diquat results in increased expression of DDIT3 protein PMID:38567716 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:80774 tauroursodeoxycholic acid multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C031655 ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of DDIT3 mRNA] PMID:37207789|PMID:38845341 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D020123 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of DDIT3 protein] PMID:37659622 13843780 DDIT3 DNA damage inducible transcript 3 gene CHEBI:9381 T-2 toxin increases expression EXP E RGD:6480464 20220308 CTD MESH:D013605 T-2 Toxin results in increased expression of DDIT3 protein PMID:34637808 13843890 PFDN2 prefoldin subunit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PFDN2 mRNA PMID:35307453 13843986 IL17B interleukin 17B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL17B mRNA PMID:35307453 13844072 BPIFB6 BPI fold containing family B member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BPIFB6 mRNA PMID:35307453 13844322 NDST4 N-deacetylase and N-sulfotransferase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NDST4 mRNA PMID:35307453 13844364 DECR2 2,4-dienoyl-CoA reductase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DECR2 mRNA PMID:35307453 13844465 PSD2 pleckstrin and Sec7 domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PSD2 mRNA PMID:35307453 13844546 PIGP phosphatidylinositol glycan anchor biosynthesis class P gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PIGP mRNA PMID:35307453 13844646 SELENOP selenoprotein P gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SELENOP mRNA PMID:35307453 13844745 FMO5 flavin containing dimethylaniline monoxygenase 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FMO5 mRNA PMID:35307453 13844769 PDPK1 3-phosphoinositide dependent protein kinase 1 gene CHEBI:34440 4-nonylphenol increases phosphorylation EXP E RGD:6480464 20240604 CTD MESH:C041594 4-nonylphenol results in increased phosphorylation of PDPK1 protein PMID:38246476 13844795 ABCA3 ATP binding cassette subfamily A member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCA3 mRNA PMID:35307453 13844870 PSCA prostate stem cell antigen gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PSCA mRNA PMID:35307453 13844878 CHAD chondroadherin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CHAD mRNA PMID:35307453 13844951 PGAP3 post-GPI attachment to proteins phospholipase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PGAP3 mRNA PMID:35307453 13844982 LMNA lamin A/C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LMNA mRNA PMID:35307453 13845036 AMBP alpha-1-microglobulin/bikunin precursor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AMBP mRNA PMID:35307453 13845036 AMBP alpha-1-microglobulin/bikunin precursor gene CHEBI:2762 antimycin A decreases uptake EXP E RGD:6480464 20191114 CTD MESH:D000968 Antimycin A results in decreased uptake of AMBP protein PMID:9019736 13845036 AMBP alpha-1-microglobulin/bikunin precursor gene CHEBI:27882 (S)-colchicine decreases uptake EXP E RGD:6480464 20191114 CTD MESH:D003078 Colchicine results in decreased uptake of AMBP protein PMID:9019736 13845036 AMBP alpha-1-microglobulin/bikunin precursor gene CHEBI:42017 2,4-dinitrophenol decreases uptake EXP E RGD:6480464 20191114 CTD MESH:D019297 2,4-Dinitrophenol results in decreased uptake of AMBP protein PMID:9019736 13845129 CARD11 caspase recruitment domain family member 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CARD11 mRNA PMID:35307453 13845335 SCN5A sodium voltage-gated channel alpha subunit 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCN5A mRNA PMID:35307453 13845426 PHB2 prohibitin 2 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of PHB2 mRNA PMID:35839969 13845486 TNFAIP8 TNF alpha induced protein 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TNFAIP8 mRNA PMID:35307453 13845813 PAPPA2 pappalysin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PAPPA2 mRNA PMID:35307453 13845844 PRR36 proline rich 36 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRR36 mRNA PMID:35307453 13845955 RAC1 Rac family small GTPase 1 gene CHEBI:4031 cyclosporin A affects localization EXP E RGD:6480464 20191114 CTD MESH:D016572 Cyclosporine affects the localization of RAC1 protein PMID:12695417 13846042 SLC35E4 solute carrier family 35 member E4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC35E4 mRNA PMID:35307453 13846063 ZCCHC2 zinc finger CCHC-type containing 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZCCHC2 mRNA PMID:35307453 13846113 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENPP6 mRNA PMID:35307453 13846129 PLLP plasmolipin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLLP mRNA PMID:35307453 13846145 FYCO1 FYVE and coiled-coil domain autophagy adaptor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FYCO1 mRNA PMID:35307453 13846242 R3HDM4 R3H domain containing 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of R3HDM4 mRNA PMID:35307453 13846278 MAP3K13 mitogen-activated protein kinase kinase kinase 13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAP3K13 mRNA PMID:35307453 13846426 PTPRD protein tyrosine phosphatase receptor type D gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PTPRD mRNA PMID:35307453 13846657 NEIL2 nei like DNA glycosylase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NEIL2 mRNA PMID:35307453 13846747 SLC26A4 solute carrier family 26 member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC26A4 mRNA PMID:35307453 13846798 UBAP1L ubiquitin associated protein 1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UBAP1L mRNA PMID:35307453 13846917 ASNS asparagine synthetase (glutamine-hydrolyzing) gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ASNS mRNA PMID:35307453 13846917 ASNS asparagine synthetase (glutamine-hydrolyzing) gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of ASNS mRNA] PMID:21852083 13847160 TMEM232 transmembrane protein 232 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM232 mRNA PMID:35307453 13847461 HBEGF heparin binding EGF like growth factor gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of HBEGF mRNA PMID:27617619 13847461 HBEGF heparin binding EGF like growth factor gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of DTR mRNA PMID:21852083 13847474 PRKCI protein kinase C iota gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PRKCI mRNA PMID:35307453 13847503 CFAP251 cilia and flagella associated protein 251 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP251 mRNA PMID:35307453 13847759 PCDH11X protocadherin 11 X-linked gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of PCDH11X mRNA PMID:25455459 13847800 CDS2 CDP-diacylglycerol synthase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDS2 protein PMID:37257635 13847825 ROPN1L rhophilin associated tail protein 1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ROPN1L mRNA PMID:35307453 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLCO1A2 mRNA PMID:35307453 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:17474 estrone 3-sulfate increases uptake EXP E RGD:6480464 20191210 CTD MESH:C017296 SLCO1A2 protein results in increased uptake of estrone sulfate PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:17474 estrone 3-sulfate multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C017296 Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; cefquinome inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Penicillins inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:17658 tylosin multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D015645 Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:195409 tilmicosin multiple interactions EXP E RGD:6480464 20230808 CTD MESH:C052319 tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:2676 amoxicillin increases uptake EXP E RGD:6480464 20191210 CTD MESH:D000658 SLCO1A2 protein results in increased uptake of Amoxicillin PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:2676 amoxicillin multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D000658 Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:27644 chlortetracycline increases uptake EXP E RGD:6480464 20191210 CTD MESH:D002751 SLCO1A2 protein results in increased uptake of Chlortetracycline PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:27644 chlortetracycline multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D002751 Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:27701 oxytetracycline increases uptake EXP E RGD:6480464 20191210 CTD MESH:D010118 SLCO1A2 protein results in increased uptake of Oxytetracycline PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:27701 oxytetracycline multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D010118 Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:27902 tetracycline increases uptake EXP E RGD:6480464 20191210 CTD MESH:D013752 SLCO1A2 protein results in increased uptake of Tetracycline PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:27902 tetracycline multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D013752 Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:28088 genistein multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D019833 Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:28197 daidzein multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C004742 daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:28819 naringin multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C005274 naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:28865 taurocholic acid increases uptake EXP E RGD:6480464 20191210 CTD MESH:D013656 SLCO1A2 protein results in increased uptake of Taurocholic Acid PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:28865 taurocholic acid multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D013656 Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; cefquinome inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Penicillins inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:3732 clarithromycin multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D017291 Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:42355 erythromycin A multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D004917 Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:4806 (-)-epigallocatechin 3-gallate multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C045651 epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:50845 doxycycline increases uptake EXP E RGD:6480464 20191210 CTD MESH:D004318 SLCO1A2 protein results in increased uptake of Doxycycline PMID:31287969 13847854 SLCO1A2 solute carrier organic anion transporter family member 1A2 gene CHEBI:50845 doxycycline multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D004318 Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] PMID:31287969 13848022 LCP2 lymphocyte cytosolic protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LCP2 mRNA PMID:35307453 13848022 LCP2 lymphocyte cytosolic protein 2 gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of LCP2 mRNA PMID:21391292 13848125 SLC47A1 solute carrier family 47 member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC47A1 mRNA PMID:35307453 13848125 SLC47A1 solute carrier family 47 member 1 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of SLC47A1 mRNA PMID:34389318 13848199 TP53BP2 tumor protein p53 binding protein 2 gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in decreased expression of TP53BP2 mRNA PMID:22497863 13848245 TGFBI transforming growth factor beta induced gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TGFBI mRNA PMID:35307453 13848418 KNG1 kininogen 1 gene CHEBI:16480 nitric oxide increases abundance EXP E RGD:6480464 20191114 CTD MESH:D009569 KNG1 protein results in increased abundance of Nitric Oxide PMID:12672649 13848418 KNG1 kininogen 1 gene CHEBI:16480 nitric oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009569 ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] PMID:12672649 13848418 KNG1 kininogen 1 gene CHEBI:3011 benazepril increases activity EXP E RGD:6480464 20191114 CTD MESH:C044946 benazepril results in increased activity of KNG1 protein modified form PMID:7890486 13848418 KNG1 kininogen 1 gene CHEBI:3750 clofibrate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate inhibits the reaction [KNG1 protein modified form results in increased expression of EDN1 protein] PMID:17105827 13848418 KNG1 kininogen 1 gene CHEBI:59877 enalaprilat dihydrate increases activity EXP E RGD:6480464 20191114 CTD MESH:D015773 Enalaprilat results in increased activity of KNG1 protein modified form PMID:7890486 13848418 KNG1 kininogen 1 gene CHEBI:68556 icatibant decreases activity EXP E RGD:6480464 20191114 CTD MESH:C065679 icatibant results in decreased activity of KNG1 protein modified form PMID:7890486 13848499 TSC22D1 TSC22 domain family member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TSC22D1 mRNA PMID:35307453 13848571 IFIT3 interferon induced protein with tetratricopeptide repeats 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFIT1 mRNA PMID:35307453 13848571 IFIT3 interferon induced protein with tetratricopeptide repeats 3 gene CHEBI:3638 chloroquine multiple interactions EXP E RGD:6480464 20220927 CTD MESH:D002738 Chloroquine inhibits the reaction [SZU-101 results in increased expression of IFIT1 mRNA] PMID:27079946 13848622 SPC25 SPC25 component of NDC80 kinetochore complex gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPC25 mRNA PMID:35307453 13848622 SPC25 SPC25 component of NDC80 kinetochore complex gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of SPC25 mRNA PMID:21852083 13848724 ERMARD ER membrane associated RNA degradation gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ERMARD mRNA PMID:35307453 13848995 ARMH1 armadillo like helical domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARMH1 mRNA PMID:35307453 13849118 TBX15 T-box transcription factor 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TBX15 mRNA PMID:35307453 13849163 TLX3 T cell leukemia homeobox 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TLX3 mRNA PMID:35307453 13849218 AP3M2 adaptor related protein complex 3 subunit mu 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AP3M2 mRNA PMID:35307453 13849240 IL4R interleukin 4 receptor gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of IL4R mRNA PMID:34389318 13849240 IL4R interleukin 4 receptor gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of IL4R mRNA PMID:18988085 13849296 DKK3 dickkopf WNT signaling pathway inhibitor 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DKK3 mRNA PMID:35307453 13849472 REEP6 receptor accessory protein 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of REEP6 mRNA PMID:35307453 13849493 PTI pancreatic trypsin inhibitor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTI mRNA PMID:35307453 13849560 CLDN10 claudin 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLDN10 mRNA PMID:35307453 13849718 DNER delta/notch like EGF repeat containing gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNER mRNA PMID:35307453 13849794 TMEM270 transmembrane protein 270 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM270 mRNA PMID:35307453 13849860 ATF2 activating transcription factor 2 gene CHEBI:25434 bis(2-chloroethyl) sulfide affects expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas affects the expression of ATF2 mRNA PMID:18988085 13849905 CLIC2 chloride intracellular channel 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLIC2 mRNA PMID:35307453 13849920 TRPM6 transient receptor potential cation channel subfamily M member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRPM6 mRNA PMID:35307453 13850049 HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HOGA1 mRNA PMID:35307453 13850107 ACSL5 acyl-CoA synthetase long chain family member 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACSL5 mRNA PMID:35307453 13850201 LNPEP leucyl and cystinyl aminopeptidase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LNPEP mRNA PMID:35307453 13850246 NENF neudesin neurotrophic factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NENF mRNA PMID:35307453 13850292 GJC3 gap junction protein gamma 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GJC3 mRNA PMID:35307453 13850355 ASB1 ankyrin repeat and SOCS box containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASB1 mRNA PMID:35307453 13850438 FAM149A family with sequence similarity 149 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM149A mRNA PMID:35307453 13850633 PYY peptide YY gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PYY mRNA PMID:35307453 13850697 ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of ADAMTS18 mRNA PMID:34933075 13850788 STARD13 StAR related lipid transfer domain containing 13 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STARD13 mRNA PMID:35307453 13850842 ALS2CL ALS2 C-terminal like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALS2CL mRNA PMID:35307453 13850979 TNPO3 transportin 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TNPO3 mRNA PMID:35307453 13851085 ALDH3A2 aldehyde dehydrogenase 3 family member A2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALDH3A2 mRNA PMID:35307453 13851106 KCNIP3 potassium voltage-gated channel interacting protein 3 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of KCNIP3 mRNA PMID:35307453 13851160 GCG glucagon gene CHEBI:17489 3',5'-cyclic AMP affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D000242 Cyclic AMP affects the susceptibility to GCG protein PMID:6253273 13851160 GCG glucagon gene CHEBI:17489 3',5'-cyclic AMP increases abundance EXP E RGD:6480464 20191114 CTD MESH:D000242 GCG protein results in increased abundance of Cyclic AMP PMID:6253273 13851303 GLG1 golgi glycoprotein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of GLG1 mRNA; deoxynivalenol results in decreased expression of GLG1 protein PMID:38403181 13851404 TSHR thyroid stimulating hormone receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TSHR mRNA PMID:35307453 13851404 TSHR thyroid stimulating hormone receptor gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of TSHR mRNA PMID:16896063 13851573 FABP6 fatty acid binding protein 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FABP6 mRNA PMID:35307453 13851573 FABP6 fatty acid binding protein 6 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of FABP6 mRNA] PMID:21852083 13851627 MYADM myeloid associated differentiation marker gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MYADM mRNA PMID:35307453 13851760 MRI1 methylthioribose-1-phosphate isomerase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRI1 mRNA PMID:35307453 13851776 APLP1 amyloid beta precursor like protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of APLP1 mRNA PMID:35307453 13851813 KRCC1 lysine rich coiled-coil 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KRCC1 mRNA PMID:35307453 13851888 SUGCT succinyl-CoA:glutarate-CoA transferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SUGCT mRNA PMID:35307453 13852063 MTFMT mitochondrial methionyl-tRNA formyltransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of MTFMT mRNA; deoxynivalenol results in decreased expression of MTFMT protein PMID:38403181 13852091 NAA25 N-alpha-acetyltransferase 25, NatB auxiliary subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NAA25 mRNA PMID:35307453 13852132 PSMB8 proteasome 20S subunit beta 8 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of PSMB8 mRNA PMID:25455459 13852132 PSMB8 proteasome 20S subunit beta 8 gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of PSMB8 mRNA PMID:22497863 13852148 SMAD9 SMAD family member 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMAD9 mRNA PMID:35307453 13852157 NAALADL1 N-acetylated alpha-linked acidic dipeptidase like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NAALADL1 mRNA PMID:35307453 13852183 SLC17A3 solute carrier family 17 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC17A3 mRNA PMID:35307453 13852324 HDAC6 histone deacetylase 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HDAC6 mRNA PMID:35307453 13852486 P2RX6 purinergic receptor P2X 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of P2RX6 mRNA PMID:35307453 13852736 STON2 stonin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STON2 mRNA PMID:35307453 13852780 PRPF3 pre-mRNA processing factor 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PRPF3 mRNA PMID:35307453 13852888 IPCEF1 interaction protein for cytohesin exchange factors 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of IPCEF1 mRNA PMID:21852083 13852908 DRAXIN dorsal inhibitory axon guidance protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DRAXIN mRNA PMID:35307453 13852919 NPHP4 nephrocystin 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NPHP4 mRNA PMID:35307453 13852967 SLC4A2 solute carrier family 4 member 2 gene CHEBI:4286 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017878 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC4A2 protein binds to SLC4A2 protein] PMID:10387099 13853019 MRPS10 mitochondrial ribosomal protein S10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS10 mRNA PMID:35307453 13853079 FOLR2 folate receptor 2 (fetal) gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FOLR2 mRNA PMID:35307453 13853131 CCT3 chaperonin containing TCP1 subunit 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCT3 mRNA PMID:35307453 13853219 OSGIN1 oxidative stress induced growth inhibitor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of OSGIN1 mRNA PMID:35307453 13853219 OSGIN1 oxidative stress induced growth inhibitor 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of OSGIN1 mRNA PMID:27617619 13853231 NUP62CL nucleoporin 62 C-terminal like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NUP62CL mRNA PMID:35307453 13853271 TFF1 trefoil factor 1 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol affects the expression of TFF1 mRNA PMID:30854615 13853395 RGN regucalcin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RGN mRNA PMID:35307453 13853395 RGN regucalcin gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of RGN mRNA PMID:34933075 13853427 ETS2 ETS proto-oncogene 2, transcription factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ETS2 mRNA PMID:35307453 13853488 CLDN4 claudin 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol analog results in decreased expression of CLDN4 protein; deoxynivalenol results in decreased expression of CLDN4 protein PMID:19289138|PMID:22859312|PMID:35307453|PMID:36596350 13853488 CLDN4 claudin 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of CLDN4 protein PMID:37257635 13853488 CLDN4 claudin 4 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C007262 Pioglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]; PPARG protein affects the reaction [Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]; T 0070907 inhibits the reaction [Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; T 0070907 inhibits the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein] PMID:36596350 13853488 CLDN4 claudin 4 gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of CLDN4 protein PMID:37659622 13853488 CLDN4 claudin 4 gene CHEBI:146195 3-acetyldeoxynivalenol multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C043247 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in decreased expression of CLDN4 protein] PMID:37659622 13853488 CLDN4 claudin 4 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of CLDN4 mRNA PMID:28069986 13853488 CLDN4 claudin 4 gene CHEBI:33709 amino acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000596 Amino Acids inhibits the reaction [Diquat results in decreased expression of CLDN4 protein] PMID:26338884 13853488 CLDN4 claudin 4 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004178 Diquat results in decreased expression of CLDN4 protein PMID:26338884 13853488 CLDN4 claudin 4 gene CHEBI:64163 diquat multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004178 Amino Acids inhibits the reaction [Diquat results in decreased expression of CLDN4 protein] PMID:26338884 13853488 CLDN4 claudin 4 gene CHEBI:8228 pioglitazone multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C060836 Pioglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein] PMID:36596350 13853488 CLDN4 claudin 4 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D020123 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in decreased expression of CLDN4 protein] PMID:37659622 13853488 CLDN4 claudin 4 gene CHEBI:9753 troglitazone increases expression EXP E RGD:6480464 20230502 CTD MESH:C057693 Troglitazone results in increased expression of CLDN4 mRNA; Troglitazone results in increased expression of CLDN4 protein PMID:36596350 13853488 CLDN4 claudin 4 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C057693 PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; T 0070907 inhibits the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein] PMID:36596350 13853580 DIXDC1 DIX domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DIXDC1 mRNA PMID:35307453 13853711 LCAT lecithin-cholesterol acyltransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LCAT mRNA PMID:35307453 13853774 FSHR follicle stimulating hormone receptor gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of FSHR mRNA PMID:32423882 13853774 FSHR follicle stimulating hormone receptor gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of FSHR mRNA PMID:32423882 13853774 FSHR follicle stimulating hormone receptor gene CHEBI:31767 lead diacetate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C008261 lead acetate results in decreased expression of FSHR mRNA PMID:29273543 13853807 EXOC6 exocyst complex component 6 gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20231003 CTD MESH:D005839 Gentamicins results in increased expression of EXOC6 mRNA PMID:28372472 13854017 TMSB15A thymosin beta 15A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMSB15A mRNA PMID:35307453 13854030 TNFAIP3 TNF alpha induced protein 3 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of TNFAIP3 mRNA PMID:37706587 13854030 TNFAIP3 TNF alpha induced protein 3 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP3 mRNA] PMID:37706587 13854030 TNFAIP3 TNF alpha induced protein 3 gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP3 mRNA] PMID:37706587 13854198 ACTR3 actin related protein 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACTR3 mRNA PMID:35307453 13854230 TAGLN2 transgelin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TAGLN2 mRNA PMID:35307453 13854230 TAGLN2 transgelin 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of TAGLN2 mRNA] PMID:21852083 13854413 WBP1 WW domain binding protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WBP1 mRNA PMID:35307453 13854425 IL1RN interleukin 1 receptor antagonist gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of IL1RN mRNA PMID:21391292 13854491 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GDPD5 mRNA PMID:35307453 13854624 ACOT8 acyl-CoA thioesterase 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACOT8 mRNA PMID:35307453 13854900 ZC3H8 zinc finger CCCH-type containing 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZC3H8 mRNA PMID:35307453 13854915 MOB3B MOB kinase activator 3B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MOB3B mRNA PMID:35307453 13854941 DUSP15 dual specificity phosphatase 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DUSP15 mRNA PMID:35307453 13855082 ITM2C integral membrane protein 2C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITM2C mRNA; deoxynivalenol results in decreased expression of ITM2C protein PMID:35307453|PMID:38403181 13855370 ANXA13 annexin A13 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ANXA13 mRNA PMID:35307453 13855422 HHIPL2 HHIP like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HHIPL2 mRNA PMID:35307453 13855446 C4H8orf34 chromosome 4 C8orf34 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C4H8ORF34 mRNA PMID:35307453 13855518 LOC100627422 ligand-dependent corepressor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LCOR mRNA PMID:35307453 13855628 CD40 CD40 molecule gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CD40 mRNA PMID:35307453 13855628 CD40 CD40 molecule gene CHEBI:16469 17beta-estradiol affects expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol affects the expression of CD40 protein PMID:15964915 13855685 RNF128 ring finger protein 128 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RNF128 mRNA PMID:35307453 13855685 RNF128 ring finger protein 128 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of RNF128 mRNA] PMID:21852083 13855699 QTRT1 queuine tRNA-ribosyltransferase catalytic subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of QTRT1 mRNA; deoxynivalenol results in increased expression of QTRT1 protein PMID:35307453|PMID:38403181 13855766 SCGN secretagogin, EF-hand calcium binding protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCGN mRNA PMID:35307453 13855785 KRAS KRAS proto-oncogene, GTPase gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of KRAS mRNA PMID:34389318 13855889 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein] PMID:28235547 13855889 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene CHEBI:16526 carbon dioxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002245 [Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein; Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein] PMID:28235547 13855889 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene CHEBI:17688 (S)-nicotine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009538 Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein] PMID:28235547 13855889 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene CHEBI:18723 nicotine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009538 Nicotine affects the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] affects the expression of CHRNA3 protein] PMID:28235547 13855937 ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ANKS4B mRNA PMID:35307453 13855968 MXD4 MAX dimerization protein 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MXD4 mRNA PMID:35307453 13855989 FGL2 fibrinogen like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FGL2 mRNA PMID:35307453 13855995 C4BPA complement component 4 binding protein alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C4BPA mRNA PMID:35307453 13855995 C4BPA complement component 4 binding protein alpha gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220927 CTD MESH:D015025 Zearalenone results in decreased expression of C4BPA mRNA PMID:34933075 13856028 SLX4 SLX4 structure-specific endonuclease subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLX4 mRNA PMID:35307453 13856062 RASA2 RAS p21 protein activator 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RASA2 mRNA PMID:35307453 13856097 ATF1 activating transcription factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ATF1 mRNA PMID:35307453 13856136 PFDN4 prefoldin subunit 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PFDN4 mRNA PMID:35307453 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCARB1 mRNA PMID:35307453 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:34310 (24S)-24-hydroxycholesterol affects localization EXP E RGD:6480464 20191114 CTD MESH:C044563 24-hydroxycholesterol affects the localization of SCARB1 protein PMID:16530456 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:47612 bezafibrate affects localization EXP E RGD:6480464 20191114 CTD MESH:D001629 Bezafibrate affects the localization of SCARB1 protein PMID:16530456 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:47612 bezafibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D001629 Bezafibrate results in increased expression of SCARB1 mRNA PMID:16530456 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:5001 fenofibrate affects localization EXP E RGD:6480464 20191114 CTD MESH:D011345 Fenofibrate affects the localization of SCARB1 protein PMID:16530456 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:8228 pioglitazone affects localization EXP E RGD:6480464 20191114 CTD MESH:C060836 Pioglitazone affects the localization of SCARB1 protein PMID:16530456 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:8228 pioglitazone increases expression EXP E RGD:6480464 20191114 CTD MESH:C060836 Pioglitazone results in increased expression of SCARB1 mRNA PMID:16530456 13856190 SCARB1 scavenger receptor class B member 1 gene CHEBI:9753 troglitazone affects localization EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone affects the localization of SCARB1 protein PMID:16530456 13856369 NME3 NME/NM23 nucleoside diphosphate kinase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NME3 mRNA PMID:35307453 13856420 KNDC1 kinase non-catalytic C-lobe domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KNDC1 mRNA PMID:35307453 13856706 NUP37 nucleoporin 37 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NUP37 mRNA PMID:35307453 13856726 NFE2 nuclear factor, erythroid 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NFE2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NFE2 protein PMID:33592257 13856726 NFE2 nuclear factor, erythroid 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NFE2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NFE2 protein PMID:33592257 13856884 PUF60 poly(U) binding splicing factor 60 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PUF60 mRNA PMID:35307453 13856990 GRAMD1C GRAM domain containing 1C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GRAMD1C mRNA PMID:35307453 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTGS1 mRNA PMID:35307453 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:15428 glycine multiple interactions EXP E RGD:6480464 20200804 CTD MESH:D005998 [Folic Acid co-treated with Glycine] results in decreased expression of PTGS1 PMID:14662146 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:22977 cadmium atom decreases expression EXP E RGD:6480464 20231031 CTD MESH:D002104 Cadmium results in decreased expression of PTGS1 mRNA PMID:37207789 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D002104 ursodoxicoltaurine inhibits the reaction [Cadmium results in decreased expression of PTGS1 mRNA] PMID:37207789 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20200804 CTD MESH:D005492 [Folic Acid co-treated with Glycine] results in decreased expression of PTGS1 PMID:14662146 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20241105 CTD MESH:C006780 bisphenol A results in decreased expression of PTGS1 mRNA PMID:38845341 13857165 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:80774 tauroursodeoxycholic acid multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C031655 ursodoxicoltaurine inhibits the reaction [Cadmium results in decreased expression of PTGS1 mRNA] PMID:37207789 13857230 DDX20 DEAD-box helicase 20 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX20 mRNA PMID:35307453 13857230 DDX20 DEAD-box helicase 20 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of DDX20 mRNA PMID:34389318 13857255 PRDX1 peroxiredoxin 1 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of PRDX1 mRNA PMID:14994279 13857275 LOC100523672 heat shock factor protein 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of NOL3 mRNA PMID:35307453 13857320 PLAT plasminogen activator, tissue type gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLAT mRNA; deoxynivalenol results in decreased expression of PLAT protein PMID:38403181 13857356 UBAP2 ubiquitin associated protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBAP2 mRNA PMID:35307453 13857459 ETNK2 ethanolamine kinase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ETNK2 mRNA PMID:35307453 13857494 BOK BCL2 family apoptosis regulator BOK gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of BOK mRNA PMID:34933075 13857508 NALF2 NALCN channel auxiliary factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAM155B mRNA PMID:35307453 13857576 HMOX2 heme oxygenase 2 gene CHEBI:3077 betamethasone increases expression EXP E RGD:6480464 20191114 CTD MESH:D001623 Betamethasone results in increased expression of HMOX2 protein PMID:11698254 13857722 TACC2 transforming acidic coiled-coil containing protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TACC2 mRNA PMID:35307453 13857761 SLC34A3 solute carrier family 34 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC34A3 mRNA PMID:35307453 13857824 CX3CL1 C-X3-C motif chemokine ligand 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CX3CL1 mRNA PMID:35307453 13857824 CX3CL1 C-X3-C motif chemokine ligand 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of CX3CL1 mRNA PMID:23326479 13857824 CX3CL1 C-X3-C motif chemokine ligand 1 gene CHEBI:3093 bifenthrin decreases expression EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin results in decreased expression of CX3CL1 mRNA PMID:33901951 13858001 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of YWHAZ mRNA PMID:34389318 13858001 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta gene CHEBI:28984 aluminium atom affects binding EXP E RGD:6480464 20191114 CTD MESH:D000535 Aluminum binds to YWHAZ protein PMID:29385627 13858001 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta gene CHEBI:28984 aluminium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000535 [Aluminum binds to YWHAZ protein] inhibits the reaction [YWHAZ protein binds to MAPT protein]; Aluminum inhibits the reaction [MAPT protein binds to YWHAZ protein] PMID:29385627 13858001 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta gene CHEBI:33629 aluminium(0) affects binding EXP E RGD:6480464 20191114 CTD MESH:D000535 Aluminum binds to YWHAZ protein PMID:29385627 13858001 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta gene CHEBI:33629 aluminium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000535 [Aluminum binds to YWHAZ protein] inhibits the reaction [YWHAZ protein binds to MAPT protein]; Aluminum inhibits the reaction [MAPT protein binds to YWHAZ protein] PMID:29385627 13858094 PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLEKHH2 mRNA PMID:35307453 13858149 SFRP4 secreted frizzled related protein 4 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of SFRP4 mRNA PMID:34389318 13858159 DDAH1 dimethylarginine dimethylaminohydrolase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDAH1 mRNA PMID:35307453 13858247 IFRD1 interferon related developmental regulator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IFRD1 mRNA; deoxynivalenol results in increased expression of IFRD1 protein PMID:35307453|PMID:38403181 13858274 FGFRL1 fibroblast growth factor receptor like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FGFRL1 mRNA PMID:35307453 13858345 DUSP23 dual specificity phosphatase 23 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DUSP23 mRNA PMID:35307453 13858574 SOBP sine oculis binding protein homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SOBP mRNA PMID:35307453 13858678 LOC102162486 putative RNA-binding protein Luc7-like 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FMC1-LUC7L2 mRNA PMID:35307453 13858762 CA11 carbonic anhydrase 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CA11 mRNA PMID:35307453 13858762 CA11 carbonic anhydrase 11 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CA11 mRNA PMID:34933075 13858942 ACAT1 acetyl-CoA acetyltransferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACAT1 mRNA; deoxynivalenol results in decreased expression of ACAT1 protein PMID:35307453|PMID:38403181 13858987 DYNLT5 dynein light chain Tctex-type family member 5 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol affects the expression of DYNLT5 mRNA PMID:35307453 13859042 YPEL4 yippee like 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of YPEL4 mRNA PMID:35307453 13859052 ANXA4 annexin A4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ANXA4 mRNA PMID:35307453 13859175 CDH22 cadherin 22 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDH22 mRNA PMID:35307453 13859191 CCDC170 coiled-coil domain containing 170 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC170 mRNA PMID:35307453 13859260 IQCC IQ motif containing C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IQCC mRNA PMID:35307453 13859274 PDCD1LG2 programmed cell death 1 ligand 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PDCD1LG2 mRNA PMID:35307453 13859304 MARCHF8 membrane associated ring-CH-type finger 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MARCHF8 mRNA PMID:35307453 13859417 ITGAM integrin subunit alpha M gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITGAM mRNA PMID:35307453 13859468 DCUN1D3 defective in cullin neddylation 1 domain containing 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DCUN1D3 mRNA PMID:35307453 13859519 DPF3 double PHD fingers 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DPF3 mRNA PMID:35307453 13859572 RIOX2 ribosomal oxygenase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RIOX2 mRNA PMID:35307453 13859697 PSMB3 proteasome 20S subunit beta 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMB3 mRNA PMID:35307453 13859958 DNM1 dynamin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DNM1 mRNA PMID:35307453 13859958 DNM1 dynamin 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of DNM1 mRNA PMID:34933075 13860007 YPEL3 yippee like 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of YPEL3 mRNA PMID:35307453 13860092 TST thiosulfate sulfurtransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TST mRNA PMID:35307453 13860209 TFG trafficking from ER to golgi regulator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TFG mRNA PMID:35307453 13860279 TMEM200A transmembrane protein 200A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM200A mRNA PMID:35307453 13860407 MRPS18C mitochondrial ribosomal protein S18C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS18C mRNA PMID:35307453 13860477 ACOX3 acyl-CoA oxidase 3, pristanoyl gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACOX3 mRNA PMID:35307453 13860522 RASL12 RAS like family 12 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of RASL12 mRNA PMID:34389318 13860584 ERCC6L ERCC excision repair 6 like, spindle assembly checkpoint helicase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ERCC6L mRNA PMID:35307453 13860595 PSMG3 proteasome assembly chaperone 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PSMG3 mRNA PMID:35307453 13860671 FOXA1 forkhead box A1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FOXA1 mRNA PMID:35307453 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:223316 (+)-artemisinin increases expression EXP E RGD:6480464 20241001 CTD MESH:C031327 artemisinin results in increased expression of CYP1A2 mRNA PMID:24176340 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:41879 dexamethasone increases expression EXP E RGD:6480464 20241001 CTD MESH:D003907 Dexamethasone results in increased expression of CYP1A2 mRNA PMID:24176340 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:47318 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases expression EXP E RGD:6480464 20241001 CTD MESH:C475093 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP1A2 mRNA PMID:24176340 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:490095 esculetin increases expression EXP E RGD:6480464 20241001 CTD MESH:C007628 esculetin results in increased expression of CYP1A2 mRNA PMID:24176340 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:76144 flunixin meglumine affects expression EXP E RGD:6480464 20191114 CTD MESH:C014558 flunixin meglumine affects the expression of CYP1A2 mRNA PMID:26366864 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:77013 beta-naphthoflavone increases expression EXP E RGD:6480464 20191114 CTD MESH:D019324 beta-Naphthoflavone results in increased expression of CYP1A2 mRNA PMID:19464568|PMID:24176340 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:77092 fenbendazole affects expression EXP E RGD:6480464 20191114 CTD MESH:D005273 Fenbendazole affects the expression of CYP1A2 mRNA PMID:26366864 13860677 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:9055 scoparone increases expression EXP E RGD:6480464 20241001 CTD MESH:C018145 scoparone results in increased expression of CYP1A2 mRNA PMID:24176340 13860757 C7H6orf52 chromosome 7 C6orf52 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C7H6ORF52 mRNA PMID:35307453 13860810 CA8 carbonic anhydrase 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CA8 mRNA PMID:35307453 13860926 SLC2A2 solute carrier family 2 member 2 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20210706 CTD MESH:C056933 fumonisin B1 results in decreased expression of SLC2A2 mRNA PMID:33443779 13860940 CDC37 cell division cycle 37, HSP90 cochaperone gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDC37 mRNA PMID:35307453 13861159 DIABLO diablo IAP-binding mitochondrial protein gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of DIABLO mRNA PMID:21645290 13861169 MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of MTRR mRNA PMID:34389318 13861283 RPP30 ribonuclease P/MRP subunit p30 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RPP30 mRNA PMID:35307453 13861434 BPIFB3 BPI fold containing family B member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BPIFB3 mRNA PMID:35307453 13861452 ARHGEF16 Rho guanine nucleotide exchange factor 16 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARHGEF16 mRNA PMID:35307453 13861517 INHBE inhibin subunit beta E gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of INHBE mRNA PMID:35307453 13861560 NOX4 NADPH oxidase 4 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of NOX4 mRNA PMID:34933075 13861603 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PIP5K1A mRNA PMID:35307453 13861753 PRMT5 protein arginine methyltransferase 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PRMT5 mRNA PMID:35307453 13861787 MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of MTHFD1L mRNA PMID:34389318 13861920 SLC40A1 solute carrier family 40 member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC40A1 mRNA PMID:35307453 13861920 SLC40A1 solute carrier family 40 member 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of SLC40A1 mRNA PMID:21852083 13861937 ABCD1 ATP binding cassette subfamily D member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCD1 mRNA PMID:35307453 13862084 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CHAC1 mRNA PMID:35307453 13862146 DEFB1 defensin beta 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of DEFB1 mRNA PMID:25701311 13862146 DEFB1 defensin beta 1 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of DEFB1 mRNA PMID:34933075 13862146 DEFB1 defensin beta 1 gene CHEBI:77732 cadmium nitrate increases expression EXP E RGD:6480464 20191114 CTD MESH:C035196 cadmium nitrate results in increased expression of DEFB1 mRNA PMID:29421334 13862175 AKR1A1 aldo-keto reductase family 1 member A1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AKR1A1 mRNA PMID:35307453 13862301 ICAM1 intercellular adhesion molecule 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ICAM1 mRNA PMID:35307453 13862301 ICAM1 intercellular adhesion molecule 1 gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20231003 CTD MESH:D005839 Gentamicins results in increased expression of ICAM1 mRNA PMID:28372472 13862301 ICAM1 intercellular adhesion molecule 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of ICAM1 mRNA PMID:18988085 13862301 ICAM1 intercellular adhesion molecule 1 gene CHEBI:29310 dichlorine increases expression EXP E RGD:6480464 20191114 CTD MESH:D002713 Chlorine results in increased expression of ICAM1 mRNA PMID:22533443 13862301 ICAM1 intercellular adhesion molecule 1 gene CHEBI:30187 aluminium oxide increases expression EXP E RGD:6480464 20191114 CTD MESH:D000537 Aluminum Oxide results in increased expression of ICAM1 protein PMID:18456438 13862301 ICAM1 intercellular adhesion molecule 1 gene CHEBI:46680 serpentine asbestos increases expression EXP E RGD:6480464 20201006 CTD MESH:D017632 Asbestos, Serpentine results in increased expression of ICAM1 mRNA PMID:8685910 13862330 FLI1 Fli-1 proto-oncogene, ETS transcription factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FLI1 mRNA PMID:35307453 13862359 NIFK nucleolar protein interacting with the FHA domain of MKI67 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NIFK mRNA PMID:35307453 13862455 CTXN1 cortexin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTXN1 mRNA PMID:35307453 13862598 RTP4 receptor transporter protein 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RTP4 mRNA PMID:35307453 13862616 RAB11FIP3 RAB11 family interacting protein 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAB11FIP3 mRNA PMID:35307453 13862646 MYT1 myelin transcription factor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYT1 mRNA PMID:35307453 13862884 NCBP1 nuclear cap binding protein subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NCBP1 mRNA PMID:35307453 13863102 MRPL17 mitochondrial ribosomal protein L17 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL17 mRNA PMID:35307453 13863116 NPAS1 neuronal PAS domain protein 1 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of NPAS1 mRNA PMID:35307453 13863158 GPRC5B G protein-coupled receptor class C group 5 member B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPRC5B mRNA PMID:35307453 13863313 SGSH N-sulfoglucosamine sulfohydrolase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SGSH mRNA PMID:35307453 13863439 POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of POMGNT1 mRNA PMID:35307453 13863478 DGKZ diacylglycerol kinase zeta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DGKZ mRNA PMID:35307453 13863602 DDX5 DEAD-box helicase 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX5 mRNA PMID:35307453 13863670 EXO1 exonuclease 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EXO1 mRNA PMID:35307453 13864007 TMEM209 transmembrane protein 209 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM209 mRNA PMID:35307453 13864051 WDR87 WD repeat domain 87 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of WDR87 mRNA PMID:35307453 13864296 PLAC8 placenta associated 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PLAC8 mRNA PMID:35307453 13864322 PEX11A peroxisomal biogenesis factor 11 alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PEX11A mRNA PMID:35307453 13864332 WASF1 WASP family member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of WASF1 mRNA PMID:35307453 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FABP4 mRNA PMID:35307453 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:17270 glycerol 2-phosphate multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C031463 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] PMID:30481989 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of FABP4 mRNA] PMID:21852083 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:29073 L-ascorbic acid multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D001205 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] PMID:30481989 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:34578 Bisphenol A diglycidyl ether multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C019273 bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] PMID:30481989 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:41879 dexamethasone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D003907 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] PMID:30481989 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:75261 arotinoid acid decreases expression EXP E RGD:6480464 20191114 CTD MESH:C038864 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased expression of FABP4 mRNA PMID:15583048 13864371 FABP4 fatty acid binding protein 4 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C057693 Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] PMID:30481989 13864417 GPRIN1 G protein regulated inducer of neurite outgrowth 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPRIN1 mRNA PMID:35307453 13864470 SLC7A11 solute carrier family 7 member 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC7A11 mRNA PMID:35307453 13864515 ASH2L ASH2 like, histone lysine methyltransferase complex subunit gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Dietary Fats promotes the reaction [Resveratrol results in decreased expression of ASH2L mRNA] PMID:21852083 13864577 FFAR2 free fatty acid receptor 2 gene CHEBI:64243 monosodium L-glutamate affects expression EXP E RGD:6480464 20200317 CTD MESH:D012970 Sodium Glutamate affects the expression of FFAR2 mRNA PMID:31360149 13864577 FFAR2 free fatty acid receptor 2 gene CHEBI:64243 monosodium L-glutamate multiple interactions EXP E RGD:6480464 20200317 CTD MESH:D012970 Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR2 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR2 mRNA] PMID:31360149 13864596 GPX6 glutathione peroxidase 6 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of GPX6 mRNA PMID:25455459 13864596 GPX6 glutathione peroxidase 6 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of GPX6 mRNA PMID:28069986 13864596 GPX6 glutathione peroxidase 6 gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of GPX6 mRNA PMID:31535366 13864626 ZAR1L zygote arrest 1 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZAR1L mRNA PMID:35307453 13864764 VIM vimentin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of VIM mRNA PMID:25701311 13864764 VIM vimentin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VIM mRNA PMID:35307453 13864870 ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABHD4 mRNA PMID:35307453 13864901 TPD52 tumor protein D52 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TPD52 mRNA PMID:35307453 13865035 SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMG1 mRNA PMID:35307453 13865222 IER5 immediate early response 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IER5 mRNA PMID:35307453 13865234 PBX1 PBX homeobox 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PBX1 mRNA PMID:35307453 13865310 SFR1 SWI5 dependent homologous recombination repair protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SFR1 mRNA; deoxynivalenol results in increased expression of SFR1 protein PMID:35307453|PMID:38403181 13865318 CXCL13 C-X-C motif chemokine ligand 13 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CXCL13 mRNA PMID:35307453 13865318 CXCL13 C-X-C motif chemokine ligand 13 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CXCL13 mRNA PMID:34933075 13865418 EPB41L1 erythrocyte membrane protein band 4.1 like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EPB41L1 mRNA PMID:35307453 13865626 GDI2 GDP dissociation inhibitor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GDI2 mRNA PMID:35307453 13865684 PNPT1 polyribonucleotide nucleotidyltransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PNPT1 mRNA PMID:35307453 13865724 OTULINL OTU deubiquitinase with linear linkage specificity like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of OTULINL mRNA PMID:35307453 13865754 EPOR erythropoietin receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EPOR mRNA PMID:35307453 13865940 KIFC1 kinesin family member C1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIFC1 mRNA PMID:35307453 13866169 PLPP1 phospholipid phosphatase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PLPP1 mRNA PMID:35307453 13866267 ITGA5 integrin subunit alpha 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITGA5 mRNA; deoxynivalenol results in decreased expression of ITGA5 protein PMID:38403181 13866306 SEL1L3 SEL1L family member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SEL1L3 mRNA PMID:35307453 13866446 SCFD2 sec1 family domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCFD2 mRNA PMID:35307453 13866539 CCDC174 coiled-coil domain containing 174 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCDC174 mRNA PMID:35307453 13866554 CCNB3 cyclin B3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCNB3 mRNA PMID:35307453 13866712 HSPH1 heat shock protein family H (Hsp110) member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HSPH1 mRNA PMID:35307453 13866759 NAA35 N-alpha-acetyltransferase 35, NatC auxiliary subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NAA35 mRNA PMID:35307453 13866895 CETN2 centrin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CETN2 mRNA PMID:35307453 13866926 ARNT aryl hydrocarbon receptor nuclear translocator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240430 CTD MESH:C007262 deoxynivalenol results in increased expression of ARNT mRNA PMID:35381244 13866926 ARNT aryl hydrocarbon receptor nuclear translocator gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C007262 AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA] PMID:35381244 13866926 ARNT aryl hydrocarbon receptor nuclear translocator gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C017947 AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA] PMID:35381244 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FIS1 mRNA PMID:33592257 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:34905 paraquat affects expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat affects the expression of FIS1 protein PMID:34811946 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat results in increased expression of FIS1 mRNA PMID:34811946 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]; MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]] PMID:34811946 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FIS1 mRNA PMID:33592257 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]] PMID:34811946 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:47807 sulforaphane decreases expression EXP E RGD:6480464 20191114 CTD MESH:C016766 sulforaphane results in decreased expression of FIS1 protein PMID:27993529 13867095 FIS1 fission, mitochondrial 1 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]] PMID:34811946 13867283 MAN2B1 mannosidase alpha class 2B member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAN2B1 mRNA PMID:35307453 13867386 KIF14 kinesin family member 14 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of KIF14 mRNA PMID:35307453 13867843 SLC30A9 solute carrier family 30 member 9 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of SLC30A9 mRNA PMID:35839969 13867865 AURKA aurora kinase A gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of AURKA mRNA PMID:35839969 13867890 ARMC5 armadillo repeat containing 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARMC5 mRNA PMID:35307453 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol affects the expression of and affects the cleavage of PARP1 protein PMID:38104654 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:22977 cadmium atom increases cleavage EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased cleavage of PARP1 protein PMID:16785314 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 GLRX protein inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; oxalomalic acid promotes the reaction [Cadmium results in increased cleavage of PARP1 protein] PMID:16785314 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:27899 cisplatin increases activity EXP E RGD:6480464 20200211 CTD MESH:D002945 Cisplatin results in increased activity of PARP1 protein PMID:25806124 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20200211 CTD MESH:D002945 N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Cisplatin results in increased activity of PARP1 protein] PMID:25806124 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:30926 3-oxalomalic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C015407 oxalomalic acid promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; oxalomalic acid promotes the reaction [Cadmium results in increased cleavage of PARP1 protein] PMID:16785314 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat results in increased expression of PARP1 protein PMID:34811946 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of PARP1 protein]]; MYD88 protein affects the reaction [Paraquat results in increased expression of PARP1 protein] PMID:34811946 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:35456 cadmium dichloride increases cleavage EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased cleavage of PARP1 protein PMID:16785314 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 GLRX protein inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; oxalomalic acid promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] PMID:16785314 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:3638 chloroquine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002738 Chloroquine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein] PMID:30287338 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025946 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of PARP1 protein]]; 3-methyladenine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein] PMID:30287338|PMID:34811946 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:7719 ochratoxin A increases cleavage EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased cleavage of PARP1 protein PMID:30287338 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20201006 CTD MESH:C025589 ochratoxin A results in increased expression of PARP1 protein PMID:32454083 13868155 PARP1 poly(ADP-ribose) polymerase 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 3-methyladenine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein]; ATG5 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein]; BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein]; Chloroquine promotes the reaction [ochratoxin A results in increased cleavage of PARP1 protein] PMID:30287338 13868222 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADAMTS17 mRNA PMID:35307453 13868380 SLC39A1 solute carrier family 39 member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC39A1 mRNA PMID:35307453 13868408 HMCN2 hemicentin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HMCN2 mRNA PMID:35307453 13868750 ACP5 acid phosphatase 5, tartrate resistant gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACP5 mRNA PMID:35307453 13868771 ZNF507 zinc finger protein 507 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of ZNF507 mRNA] PMID:21852083 13868829 SNX32 sorting nexin 32 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SNX32 mRNA PMID:35307453 13868900 URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of URAD mRNA PMID:35307453 13868978 CD99L2 CD99 molecule like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CD99L2 mRNA PMID:35307453 13869005 PIF1 PIF1 5'-to-3' DNA helicase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PIF1 mRNA PMID:35307453 13869115 TYRP1 tyrosinase related protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TYRP1 mRNA PMID:35307453 13869133 CREB5 cAMP responsive element binding protein 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CREB5 mRNA PMID:35307453 13869217 TMEM69 transmembrane protein 69 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM69 mRNA PMID:35307453 13869374 CALU calumenin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CALU mRNA PMID:35307453 13869395 BMS1 BMS1 ribosome biogenesis factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BMS1 mRNA PMID:35307453 13869453 ASAH2 N-acylsphingosine amidohydrolase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASAH2 mRNA PMID:35307453 13869578 GPATCH2L G-patch domain containing 2 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GPATCH2L mRNA PMID:35307453 13869738 PRKX protein kinase cAMP-dependent X-linked catalytic subunit gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRKX mRNA PMID:35307453 13869753 ADGRF1 adhesion G protein-coupled receptor F1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADGRF1 mRNA PMID:35307453 13869816 DUSP12 dual specificity phosphatase 12 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DUSP12 mRNA PMID:35307453 13869856 GPAT3 glycerol-3-phosphate acyltransferase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GPAT3 mRNA PMID:35307453 13870155 TNFSF13B TNF superfamily member 13b gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TNFSF13B mRNA PMID:35307453 13870216 MRPL51 mitochondrial ribosomal protein L51 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL51 mRNA PMID:35307453 13870231 ANXA5 annexin A5 gene CHEBI:17351 linoleic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:D019787 Linoleic Acid results in increased activity of ANXA5 protein PMID:10617950 13870231 ANXA5 annexin A5 gene CHEBI:17351 linoleic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019787 Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]] PMID:10617950 13870231 ANXA5 annexin A5 gene CHEBI:62984 zinc acetate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019345 Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]] PMID:10617950 13870231 ANXA5 annexin A5 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of ANXA5 mRNA PMID:14994279 13870231 ANXA5 annexin A5 gene CHEBI:88217 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C044387 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]] PMID:10617950 13870334 PSMC5 proteasome 26S subunit, ATPase 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMC5 mRNA PMID:35307453 13870378 CCNB1IP1 cyclin B1 interacting protein 1 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of CCNB1IP1 mRNA PMID:28069986 13870570 DGAT2 diacylglycerol O-acyltransferase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DGAT2 mRNA PMID:35307453 13870915 ANGEL1 angel homolog 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ANGEL1 mRNA PMID:35307453 13871011 NR0B1 nuclear receptor subfamily 0 group B member 1 gene CHEBI:177470 Cloprostenol increases expression EXP E RGD:6480464 20210907 CTD MESH:D003008 Cloprostenol results in increased expression of NR0B1 mRNA PMID:15713365 13871173 VTN vitronectin gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of VTN mRNA PMID:34389318 13871185 ARHGAP44 Rho GTPase activating protein 44 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARHGAP44 mRNA PMID:35307453 13871214 ERC1 ELKS/RAB6-interacting/CAST family member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ERC1 mRNA PMID:35307453 13871421 IL17C interleukin 17C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL17C mRNA PMID:35307453 13871550 CTNNA3 catenin alpha 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTNNA3 mRNA PMID:35307453 13871550 CTNNA3 catenin alpha 3 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of CTNNA3 mRNA PMID:18988085 13871614 GPR179 G protein-coupled receptor 179 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPR179 mRNA PMID:35307453 13871645 POLQ DNA polymerase theta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of POLQ mRNA PMID:35307453 13871732 POLR1G RNA polymerase I subunit G gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230207 CTD MESH:C007262 deoxynivalenol results in increased expression of POLR1G mRNA PMID:35307453 13871792 H2BC11 H2B clustered histone 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230404 CTD MESH:C007262 deoxynivalenol results in increased expression of H2BC11 mRNA PMID:35307453 13871850 GSDMD gasdermin D gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C007262 belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein] PMID:36309173 13871850 GSDMD gasdermin D gene CHEBI:15891 taurine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D013654 Taurine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein] PMID:36281498 13871850 GSDMD gasdermin D gene CHEBI:188567 Belnacasan multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C520022 belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein] PMID:36309173 13871850 GSDMD gasdermin D gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D000111 Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein] PMID:36281498 13871850 GSDMD gasdermin D gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C056933 belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; belnacasan inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of GSDMD protein] PMID:36309173 13871850 GSDMD gasdermin D gene CHEBI:4948 Evodiamine multiple interactions EXP E RGD:6480464 20250114 CTD MESH:C049639 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in increased expression of GSDMD protein]]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of GSDMD protein] PMID:39305878 13871850 GSDMD gasdermin D gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20230502 CTD MESH:C025589 ochratoxin A results in increased expression of GSDMD protein PMID:36281498 13871850 GSDMD gasdermin D gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C025589 Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein]; Taurine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein] PMID:36281498 13871850 GSDMD gasdermin D gene CHEBI:9381 T-2 toxin increases expression EXP E RGD:6480464 20250114 CTD MESH:D013605 T-2 Toxin results in increased expression of GSDMD protein PMID:39305878 13871850 GSDMD gasdermin D gene CHEBI:9381 T-2 toxin multiple interactions EXP E RGD:6480464 20250114 CTD MESH:D013605 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in increased expression of GSDMD protein]]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of GSDMD protein] PMID:39305878 13872031 LY6G6C lymphocyte antigen 6 family member G6C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LY6G6C mRNA PMID:35307453 13872060 MMP15 matrix metallopeptidase 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MMP15 mRNA PMID:35307453 13872130 TMEM116 transmembrane protein 116 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM116 mRNA PMID:35307453 13872202 TRIM13 tripartite motif containing 13 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of TRIM13 mRNA] PMID:21852083 13872228 TRADD TNFRSF1A associated via death domain gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20200714 CTD MESH:C056933 fumonisin B1 results in increased expression of TRADD mRNA PMID:32198028 13872249 PDX1 pancreatic and duodenal homeobox 1 gene CHEBI:9168 sirolimus decreases expression EXP E RGD:6480464 20191114 CTD MESH:D020123 Sirolimus results in decreased expression of PDX1 mRNA PMID:20622751 13872256 DBNDD1 dysbindin domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DBNDD1 mRNA PMID:35307453 13872279 CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CAMKK2 mRNA PMID:35307453 13872426 MNX1 motor neuron and pancreas homeobox 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MNX1 mRNA PMID:35307453 13872433 INTS13 integrator complex subunit 13 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of INTS13 mRNA PMID:35307453 13872518 ALOX5AP arachidonate 5-lipoxygenase activating protein gene CHEBI:2825 aristolochic acid A increases expression EXP E RGD:6480464 20191114 CTD MESH:C000228 aristolochic acid I results in increased expression of ALOX5AP protein PMID:21658425 13872518 ALOX5AP arachidonate 5-lipoxygenase activating protein gene CHEBI:2825 aristolochic acid A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C000228 MK-886 inhibits the reaction [aristolochic acid I results in increased expression of ALOX5AP protein]; U 0126 inhibits the reaction [aristolochic acid I results in increased expression of ALOX5AP protein] PMID:21658425 13872518 ALOX5AP arachidonate 5-lipoxygenase activating protein gene CHEBI:75390 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C060893 MK-886 inhibits the reaction [aristolochic acid I results in increased expression of ALOX5AP protein] PMID:21658425 13872538 LARS1 leucyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LARS1 mRNA PMID:35307453 13872621 CXXC5 CXXC finger protein 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of CXXC5 mRNA; deoxynivalenol results in decreased expression of CXXC5 protein PMID:38403181 13872661 KIF5B kinesin family member 5B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KIF5B mRNA PMID:35307453 13873117 FAM151A family with sequence similarity 151 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM151A mRNA PMID:35307453 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACACA mRNA PMID:35307453 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:16469 17beta-estradiol increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased phosphorylation of ACACA protein PMID:15967841 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:17234 glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of ACACA mRNA PMID:25827716 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:17234 glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA] PMID:25827716 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:17634 D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of ACACA mRNA PMID:25827716 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:17634 D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA] PMID:25827716 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:42758 aldehydo-D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of ACACA mRNA PMID:25827716 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:42758 aldehydo-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA] PMID:25827716 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:64243 monosodium L-glutamate increases expression EXP E RGD:6480464 20200317 CTD MESH:D012970 Sodium Glutamate results in increased expression of ACACA mRNA PMID:31360149 13873255 ACACA acetyl-CoA carboxylase alpha gene CHEBI:64243 monosodium L-glutamate multiple interactions EXP E RGD:6480464 20200317 CTD MESH:D012970 Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of ACACA mRNA] PMID:31360149 13873510 CDHR2 cadherin related family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDHR2 mRNA PMID:35307453 13873652 ETFRF1 electron transfer flavoprotein regulatory factor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ETFRF1 mRNA PMID:35307453 13873718 ARHGEF28 Rho guanine nucleotide exchange factor 28 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARHGEF28 mRNA PMID:35307453 13873807 CCKBR cholecystokinin B receptor gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of CCKBR mRNA PMID:34933075 13873831 TTC36 tetratricopeptide repeat domain 36 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TTC36 mRNA PMID:35307453 13873846 SLC39A8 solute carrier family 39 member 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC39A8 mRNA PMID:35307453 13873942 RIPOR2 RHO family interacting cell polarization regulator 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RIPOR2 mRNA PMID:35307453 13873942 RIPOR2 RHO family interacting cell polarization regulator 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of RIPOR2 mRNA PMID:21852083 13874180 UBA7 ubiquitin like modifier activating enzyme 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UBA7 mRNA PMID:35307453 13874250 BPIFB2 BPI fold containing family B member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BPIFB2 mRNA PMID:35307453 13874296 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENPP5 mRNA PMID:35307453 13874309 CAV2 caveolin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CAV2 mRNA PMID:35307453 13874413 MRPS35 mitochondrial ribosomal protein S35 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS35 mRNA PMID:35307453 13874478 MTPAP mitochondrial poly(A) polymerase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MTPAP mRNA PMID:35307453 13874602 RPRML reprimo like gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of RPRML mRNA PMID:34933075 13874607 SGCA sarcoglycan alpha gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SGCA mRNA PMID:35307453 13874704 DHFR dihydrofolate reductase gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of DHFR mRNA PMID:22497863 13874726 LHB luteinizing hormone subunit beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LHB mRNA PMID:35307453 13874726 LHB luteinizing hormone subunit beta gene CHEBI:16422 androst-4-ene-3,17-dione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000735 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; [LHB protein co-treated with INS protein] results in increased abundance of Androstenedione; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione] PMID:11889176 13874726 LHB luteinizing hormone subunit beta gene CHEBI:16469 17beta-estradiol increases secretion EXP E RGD:6480464 20191114 CTD MESH:D004958 LHB protein results in increased secretion of Estradiol PMID:26055946 13874726 LHB luteinizing hormone subunit beta gene CHEBI:16469 17beta-estradiol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004958 Biological Products inhibits the reaction [LHB protein results in increased secretion of Estradiol]; Cod Liver Oil inhibits the reaction [LHB protein results in increased secretion of Estradiol]; Industrial Waste inhibits the reaction [LHB protein results in increased secretion of Estradiol] PMID:26055946 13874726 LHB luteinizing hormone subunit beta gene CHEBI:17026 progesterone increases abundance EXP E RGD:6480464 20191114 CTD MESH:D011374 LHB protein results in increased abundance of Progesterone PMID:19617652|PMID:23375200 13874726 LHB luteinizing hormone subunit beta gene CHEBI:17026 progesterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011374 daidzein inhibits the reaction [LHB protein results in increased abundance of Progesterone]; Lapatinib inhibits the reaction [LHB protein results in increased abundance of Progesterone] PMID:19617652|PMID:23375200 13874726 LHB luteinizing hormone subunit beta gene CHEBI:17347 testosterone increases secretion EXP E RGD:6480464 20191114 CTD MESH:D013739 LHB protein results in increased secretion of Testosterone PMID:26055946 13874726 LHB luteinizing hormone subunit beta gene CHEBI:17347 testosterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013739 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; [LHB protein co-treated with INS protein] results in increased abundance of Testosterone; Biological Products inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Cod Liver Oil inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Industrial Waste inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone] PMID:11889176|PMID:26055946 13874726 LHB luteinizing hormone subunit beta gene CHEBI:27485 prostaglandin J2 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C037112 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA] PMID:11889176 13874726 LHB luteinizing hormone subunit beta gene CHEBI:27638 cobalt atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003035 [Cobalt binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:15833593 13874726 LHB luteinizing hormone subunit beta gene CHEBI:28112 nickel atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009532 [Nickel binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:16892001 13874726 LHB luteinizing hormone subunit beta gene CHEBI:28197 daidzein multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C004742 daidzein inhibits the reaction [LHB protein results in increased abundance of Progesterone] PMID:19617652 13874726 LHB luteinizing hormone subunit beta gene CHEBI:28694 copper atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003300 [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:16892001 13874726 LHB luteinizing hormone subunit beta gene CHEBI:30052 copper(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003300 [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:16892001 13874726 LHB luteinizing hormone subunit beta gene CHEBI:49603 lapatinib decreases activity EXP E RGD:6480464 20191114 CTD MESH:C490728 Lapatinib results in decreased activity of LHB protein PMID:23375200 13874726 LHB luteinizing hormone subunit beta gene CHEBI:49603 lapatinib multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C490728 Lapatinib inhibits the reaction [LHB protein results in increased abundance of Progesterone] PMID:23375200 13874726 LHB luteinizing hormone subunit beta gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 protein modified form] PMID:11889176 13874758 ADIPOR1 adiponectin receptor 1 gene CHEBI:16469 17beta-estradiol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased expression of ADIPOR1 protein PMID:28284726 13874758 ADIPOR1 adiponectin receptor 1 gene CHEBI:17347 testosterone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013739 Testosterone results in decreased expression of ADIPOR1 protein PMID:28284726 13874758 ADIPOR1 adiponectin receptor 1 gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of ADIPOR1 protein PMID:28284726 13874758 ADIPOR1 adiponectin receptor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of ADIPOR1 protein PMID:28284726 13874758 ADIPOR1 adiponectin receptor 1 gene CHEBI:5692 hexachlorobenzene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D006581 Hexachlorobenzene results in decreased expression of ADIPOR1 protein PMID:28284726 13874758 ADIPOR1 adiponectin receptor 1 gene CHEBI:81584 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP E RGD:6480464 20191114 CTD MESH:C511295 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ADIPOR1 protein PMID:28284726 13874801 TRPM2 transient receptor potential cation channel subfamily M member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRPM2 mRNA PMID:35307453 13874932 MXRA7 matrix remodeling associated 7 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of MXRA7 mRNA PMID:34933075 13874966 CAP2 cyclase associated actin cytoskeleton regulatory protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CAP2 mRNA PMID:35307453 13875307 PFN1 profilin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PFN1 mRNA PMID:35307453 13875358 ITGB2 integrin subunit beta 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITGB2 mRNA PMID:35307453 13875358 ITGB2 integrin subunit beta 2 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of ITGB2 mRNA PMID:18988085 13875358 ITGB2 integrin subunit beta 2 gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of ITGB2 mRNA PMID:21391292 13875358 ITGB2 integrin subunit beta 2 gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of ITGB2 mRNA PMID:22497863 13875629 ATR ATR serine/threonine kinase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ATR mRNA PMID:35307453 13875629 ATR ATR serine/threonine kinase gene CHEBI:16240 hydrogen peroxide decreases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in decreased expression of ATR mRNA PMID:37706587 13875629 ATR ATR serine/threonine kinase gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATR mRNA] PMID:37706587 13875629 ATR ATR serine/threonine kinase gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATR mRNA] PMID:37706587 13875718 LOC102159820 cadherin EGF LAG seven-pass G-type receptor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CELSR1 mRNA PMID:35307453 13875814 CDKN2C cyclin dependent kinase inhibitor 2C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDKN2C mRNA PMID:35307453 13875882 CAV1 caveolin 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C028451 3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein] PMID:19608276|PMID:20406653 13875882 CAV1 caveolin 1 gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein] PMID:19608276 13875882 CAV1 caveolin 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C023035 CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; CAV1 mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] PMID:19265715|PMID:20406653|PMID:24709675 13875882 CAV1 caveolin 1 gene CHEBI:8772 raloxifene increases expression EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride results in increased expression of CAV1 protein PMID:16680078 13875973 FAM72A family with sequence similarity 72 member A gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of FAM72A mRNA PMID:21852083 13876116 CCR2 C-C motif chemokine receptor 2 gene CHEBI:15553 prostaglandin F2alpha increases expression EXP E RGD:6480464 20191114 CTD MESH:D015237 Dinoprost results in increased expression of CCR2 mRNA PMID:21505051 13876116 CCR2 C-C motif chemokine receptor 2 gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015237 epostane promotes the reaction [Dinoprost results in increased expression of CCR2 mRNA] PMID:21505051 13876116 CCR2 C-C motif chemokine receptor 2 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CCR2 mRNA PMID:34389318 13876116 CCR2 C-C motif chemokine receptor 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CCR2 mRNA PMID:21852083 13876254 CCDC60 coiled-coil domain containing 60 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCDC60 mRNA PMID:35307453 13876272 NFE2L3 NFE2 like bZIP transcription factor 3 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of NFE2L3 mRNA PMID:35307453 13876283 SLC38A3 solute carrier family 38 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC38A3 mRNA PMID:35307453 13876424 MGAT5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MGAT5 mRNA PMID:35307453 13876473 PLA1A phospholipase A1 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLA1A mRNA PMID:35307453 13876491 LEFTY2 left-right determination factor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LEFTY2 mRNA PMID:35307453 13876497 KRR1 KRR1 small subunit processome component homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KRR1 mRNA PMID:35307453 13876531 JUNB JunB proto-oncogene, AP-1 transcription factor subunit gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of JUNB mRNA PMID:37706587 13876531 JUNB JunB proto-oncogene, AP-1 transcription factor subunit gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of JUNB mRNA] PMID:37706587 13876531 JUNB JunB proto-oncogene, AP-1 transcription factor subunit gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of JUNB mRNA] PMID:37706587 13876647 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002945 Cisplatin inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306] PMID:24800945 13876647 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 gene CHEBI:3000 beauvericin decreases activity EXP E RGD:6480464 20191114 CTD MESH:C004456 beauvericin results in decreased activity of ABCB1 protein PMID:27474255 13876647 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 gene CHEBI:3000 beauvericin increases expression EXP E RGD:6480464 20191114 CTD MESH:C004456 beauvericin results in increased expression of ABCB1 mRNA PMID:27474255 13876647 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 gene CHEBI:76144 flunixin meglumine affects expression EXP E RGD:6480464 20191114 CTD MESH:C014558 flunixin meglumine affects the expression of ABCB1 mRNA PMID:26366864 13876647 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 gene CHEBI:77092 fenbendazole affects expression EXP E RGD:6480464 20191114 CTD MESH:D005273 Fenbendazole affects the expression of ABCB1 mRNA PMID:26366864 13876703 IGFBP7 insulin like growth factor binding protein 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IGFBP7 mRNA; deoxynivalenol results in decreased expression of IGFBP7 protein PMID:35307453|PMID:38403181 13876712 BAG2 BAG cochaperone 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BAG2 mRNA PMID:35307453 13876750 RAB20 RAB20, member RAS oncogene family gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAB20 mRNA PMID:35307453 13876756 FIGN fidgetin, microtubule severing factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FIGN mRNA PMID:35307453 13876767 CSAD cysteine sulfinic acid decarboxylase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CSAD mRNA PMID:35307453 13876812 POLR1F RNA polymerase I subunit F gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of POLR1F mRNA PMID:35307453 13876947 ECHDC2 enoyl-CoA hydratase domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ECHDC2 mRNA PMID:35307453 13877087 RAPGEF5 Rap guanine nucleotide exchange factor 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAPGEF5 mRNA PMID:35307453 13877290 ODAPH odontogenesis associated phosphoprotein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ODAPH mRNA PMID:35307453 13877343 POGLUT2 protein O-glucosyltransferase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of POGLUT2 mRNA PMID:35307453 13877475 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NUCKS1 mRNA PMID:35307453 13877651 DNAH3 dynein axonemal heavy chain 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAH3 mRNA PMID:35307453 13877717 SIRT6 sirtuin 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SIRT6 mRNA PMID:35307453 13877839 ITFG1 integrin alpha FG-GAP repeat containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITFG1 mRNA PMID:35307453 13878136 TCEAL2 transcription elongation factor A like 2 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of TCEAL2 mRNA PMID:34389318 13878266 HNRNPLL heterogeneous nuclear ribonucleoprotein L like gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of HNRNPLL mRNA] PMID:21852083 13878341 DDX18 DEAD-box helicase 18 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX18 mRNA PMID:35307453 13878399 EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EHHADH mRNA PMID:35307453 13878411 NOP58 NOP58 ribonucleoprotein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NOP58 mRNA PMID:35307453 13878472 TMEM92 transmembrane protein 92 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM92 mRNA PMID:35307453 13878540 HOXB5 homeobox B5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HOXB5 mRNA PMID:35307453 13878573 ITGB1 integrin subunit beta 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITGB1 protein PMID:38403181 13878573 ITGB1 integrin subunit beta 1 gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of ITGB1 mRNA PMID:32423882 13878573 ITGB1 integrin subunit beta 1 gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of ITGB1 mRNA PMID:32423882 13878778 MAMDC2 MAM domain containing 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of MAMDC2 mRNA PMID:21852083 13878797 CC2D2A coiled-coil and C2 domain containing 2A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CC2D2A mRNA PMID:35307453 13878953 MBOAT2 membrane bound O-acyltransferase domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MBOAT2 mRNA PMID:35307453 13878984 AMBRA1 autophagy and beclin 1 regulator 1 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of AMBRA1 mRNA PMID:35839969 13879055 POP1 POP1 homolog, ribonuclease P/MRP subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of POP1 mRNA PMID:35307453 13879180 FAM120C family with sequence similarity 120 member C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAM120C mRNA PMID:35307453 13879209 TNFSF11 TNF superfamily member 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TNFSF11 mRNA PMID:35307453 13879275 SAFB2 scaffold attachment factor B2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SAFB2 mRNA PMID:35307453 13879342 MMP8 matrix metallopeptidase 8 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of MMP8 mRNA PMID:34933075 13879478 KIAA1328 KIAA1328 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KIAA1328 mRNA PMID:35307453 13879567 SASH3 SAM and SH3 domain containing 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SASH3 mRNA PMID:35307453 13879579 VAT1L vesicle amine transport 1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VAT1L mRNA PMID:35307453 13879681 VTA1 vesicle trafficking 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VTA1 mRNA PMID:35307453 13879696 ATL2 atlastin GTPase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ATL2 mRNA PMID:35307453 13879752 PPP1R15A protein phosphatase 1 regulatory subunit 15A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R15A mRNA PMID:35307453 13879767 THY1 Thy-1 cell surface antigen gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of THY1 mRNA PMID:35307453 13879864 METTL21A methyltransferase 21A, HSPA lysine gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of METTL21A mRNA PMID:35307453 13879893 TIMP4 TIMP metallopeptidase inhibitor 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TIMP4 mRNA PMID:35307453 13879932 RSPH1 radial spoke head component 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RSPH1 mRNA PMID:35307453 13879997 ANAPC15 anaphase promoting complex subunit 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ANAPC15 mRNA PMID:35307453 13880069 CFLAR CASP8 and FADD like apoptosis regulator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CFLAR mRNA PMID:35307453 13880069 CFLAR CASP8 and FADD like apoptosis regulator gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of CFLAR mRNA PMID:21645290 13880215 DENND11 DENN domain containing 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DENND11 mRNA PMID:35307453 13880264 HDGF heparin binding growth factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HDGF mRNA PMID:35307453 13880328 MIR331 microRNA mir-331 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20201006 CTD MESH:D015025 Zearalenone results in increased expression of MIR331 mRNA PMID:32439583 13880386 SARNP SAP domain containing ribonucleoprotein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SARNP mRNA PMID:35307453 13880401 MYH13 myosin heavy chain 13 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of MYH13 mRNA PMID:34933075 13880441 NUDT17 nudix hydrolase 17 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NUDT17 mRNA PMID:35307453 13880462 RENBP renin binding protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RENBP mRNA PMID:35307453 13880501 PDIA2 protein disulfide isomerase family A member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDIA2 mRNA PMID:35307453 13880588 FAM89A family with sequence similarity 89 member A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAM89A mRNA PMID:35307453 13880595 RRP15 ribosomal RNA processing 15 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RRP15 mRNA PMID:35307453 13880904 FTSJ1 FtsJ RNA 2'-O-methyltransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FTSJ1 mRNA PMID:35307453 13880940 FUT11 fucosyltransferase 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FUT11 mRNA PMID:35307453 13881029 HDGFL3 HDGF like 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of HDGFL3 mRNA; deoxynivalenol results in increased expression of HDGFL3 protein PMID:38403181 13881131 TTC9C tetratricopeptide repeat domain 9C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TTC9C mRNA PMID:35307453 13881388 SON SON DNA and RNA binding protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SON mRNA PMID:35307453 13881444 CFAP410 cilia and flagella associated protein 410 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP410 mRNA PMID:35307453 13881499 KIRREL3 kirre like nephrin family adhesion molecule 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIRREL3 mRNA PMID:35307453 13881562 MRPL15 mitochondrial ribosomal protein L15 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL15 mRNA PMID:35307453 13881578 PPP1R13L protein phosphatase 1 regulatory subunit 13 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R13L mRNA PMID:35307453 13881653 SCP2 sterol carrier protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCP2 mRNA PMID:35307453 13881676 IFT74 intraflagellar transport 74 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IFT74 mRNA PMID:35307453 13881774 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 gene CHEBI:10022 deoxynivalenol increases phosphorylation EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased phosphorylation of PRKAA2 protein PMID:35307453 13881774 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAA2 mRNA PMID:34416349 13881774 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAA2 mRNA PMID:34416349 13881795 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PAFAH1B1 mRNA PMID:35307453 13881907 CYP2C42 cytochrome P450 C42 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP2C42 mRNA PMID:35307453 13881919 C5 complement C5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C5 mRNA PMID:35307453 13881919 C5 complement C5 gene CHEBI:8093 phenylephrine affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D010656 C5 protein affects the susceptibility to Phenylephrine PMID:10750764 13882026 PAQR8 progestin and adipoQ receptor family member 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PAQR8 mRNA PMID:35307453 13882130 ZBBX zinc finger B-box domain containing gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZBBX mRNA PMID:35307453 13882246 IL12A interleukin 12A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IL12A mRNA PMID:35307453 13882246 IL12A interleukin 12A gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased expression of IL12A mRNA PMID:15998543 13882246 IL12A interleukin 12A gene CHEBI:28640 lipoteichoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:C009900 lipoteichoic acid results in increased expression of IL12A mRNA PMID:15998543 13882274 UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230606 CTD MESH:C007262 deoxynivalenol results in increased expression of UQCC2 mRNA PMID:35307453 13882282 DAPK2 death associated protein kinase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DAPK2 mRNA PMID:35307453 13882356 BTN2A2 butyrophilin subfamily 2 member A2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BTN2A2 mRNA PMID:35307453 13882411 SLC25A10 solute carrier family 25 member 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC25A10 mRNA PMID:35307453 13882461 ARSG arylsulfatase G gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARSG mRNA PMID:35307453 13882461 ARSG arylsulfatase G gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of ARSG mRNA PMID:21852083 13882842 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LETM1 mRNA PMID:35307453 13882958 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EPRS1 mRNA PMID:35307453 13883032 CALD1 caldesmon 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of CALD1 mRNA; deoxynivalenol results in decreased expression of CALD1 protein PMID:38403181 13883032 CALD1 caldesmon 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CALD1 mRNA PMID:21852083 13883032 CALD1 caldesmon 1 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of CALD1 mRNA PMID:35839969 13883106 ATP5F1A ATP synthase F1 subunit alpha gene CHEBI:50842 norflurazon decreases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased expression of ATP5F1A mRNA PMID:38432436 13883184 BCL10 BCL10 immune signaling adaptor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BCL10 mRNA PMID:35307453 13883407 VWDE von Willebrand factor D and EGF domains gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VWDE mRNA PMID:35307453 13883449 PDGFC platelet derived growth factor C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PDGFC mRNA PMID:35307453 13883463 PLEKHG4B pleckstrin homology and RhoGEF domain containing G4B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLEKHG4B mRNA PMID:35307453 13883498 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMURF1 mRNA PMID:35307453 13883558 CCDC107 coiled-coil domain containing 107 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCDC107 mRNA PMID:35307453 13883570 MACF1 microtubule actin crosslinking factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MACF1 mRNA PMID:35307453 13883674 UBA6 ubiquitin like modifier activating enzyme 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBA6 mRNA PMID:35307453 13883754 HS3ST2 heparan sulfate-glucosamine 3-sulfotransferase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HS3ST2 mRNA PMID:35307453 13883822 MAPT microtubule associated protein tau gene CHEBI:28984 aluminium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000535 [Aluminum binds to YWHAZ protein] inhibits the reaction [YWHAZ protein binds to MAPT protein]; Aluminum affects the expression of and affects the phosphorylation of and affects the localization of MAPT protein; Aluminum inhibits the reaction [MAPT protein binds to YWHAZ protein] PMID:29385627 13883822 MAPT microtubule associated protein tau gene CHEBI:33629 aluminium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000535 [Aluminum binds to YWHAZ protein] inhibits the reaction [YWHAZ protein binds to MAPT protein]; Aluminum affects the expression of and affects the phosphorylation of and affects the localization of MAPT protein; Aluminum inhibits the reaction [MAPT protein binds to YWHAZ protein] PMID:29385627 13883886 CASR calcium sensing receptor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CASR mRNA PMID:35307453 13884038 ATF4 activating transcription factor 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ATF4 mRNA; deoxynivalenol results in increased expression of ATF4 protein PMID:35307453|PMID:37442268|PMID:38608924 13884038 ATF4 activating transcription factor 4 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 GSK2656157 inhibits the reaction [deoxynivalenol results in increased expression of ATF4 protein]; Selenium analog inhibits the reaction [deoxynivalenol results in increased expression of ATF4 protein] PMID:37442268 13884038 ATF4 activating transcription factor 4 gene CHEBI:139047 GSK2656157 multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C000597302 GSK2656157 inhibits the reaction [deoxynivalenol results in increased expression of ATF4 protein] PMID:37442268 13884038 ATF4 activating transcription factor 4 gene CHEBI:16170 mercury(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased expression of ATF4 protein PMID:16759985 13884038 ATF4 activating transcription factor 4 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein] PMID:36584959 13884038 ATF4 activating transcription factor 4 gene CHEBI:207229 dihydroartemisinin increases expression EXP E RGD:6480464 20210504 CTD MESH:C039060 artenimol results in increased expression of ATF4 mRNA; artenimol results in increased expression of ATF4 protein PMID:32721431 13884038 ATF4 activating transcription factor 4 gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased expression of ATF4 mRNA; Cadmium results in increased expression of ATF4 protein PMID:16759985|PMID:37207789 13884038 ATF4 activating transcription factor 4 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 protein; Cycloheximide inhibits the reaction [Cadmium results in increased expression of ATF4 protein]; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of ATF4 mRNA] PMID:16759985|PMID:33891997|PMID:37207789 13884038 ATF4 activating transcription factor 4 gene CHEBI:25195 mercury atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased expression of ATF4 protein PMID:16759985 13884038 ATF4 activating transcription factor 4 gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased expression of ATF4 protein] PMID:37442268 13884038 ATF4 activating transcription factor 4 gene CHEBI:27641 cycloheximide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003513 Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of ATF4 protein]; Cycloheximide inhibits the reaction [Cadmium results in increased expression of ATF4 protein] PMID:16759985 13884038 ATF4 activating transcription factor 4 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of ATF4 mRNA; Glyphosate results in increased expression of ATF4 protein PMID:36584959 13884038 ATF4 activating transcription factor 4 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein] PMID:36584959 13884038 ATF4 activating transcription factor 4 gene CHEBI:29865 benzo[a]pyrene increases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in increased expression of ATF4 protein PMID:36754226 13884038 ATF4 activating transcription factor 4 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D001564 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of ATF4 protein] PMID:36754226 13884038 ATF4 activating transcription factor 4 gene CHEBI:31823 mercury dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased expression of ATF4 protein PMID:16759985 13884038 ATF4 activating transcription factor 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of ATF4 mRNA; bisphenol A results in increased expression of ATF4 protein PMID:37108405|PMID:38845341 13884038 ATF4 activating transcription factor 4 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF4 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of ATF4 mRNA] PMID:37108405|PMID:38845341 13884038 ATF4 activating transcription factor 4 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased expression of ATF4; Cadmium Chloride results in increased expression of ATF4 mRNA; Cadmium Chloride results in increased expression of ATF4 protein PMID:16759985|PMID:20600546 13884038 ATF4 activating transcription factor 4 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 protein; Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of ATF4 protein] PMID:16759985|PMID:33891997 13884038 ATF4 activating transcription factor 4 gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased expression of ATF4 protein] PMID:37442268 13884038 ATF4 activating transcription factor 4 gene CHEBI:41500 4-phenylbutyric acid multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C075773 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of ATF4 protein] PMID:36754226 13884038 ATF4 activating transcription factor 4 gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D018038 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF4 protein] PMID:37108405 13884038 ATF4 activating transcription factor 4 gene CHEBI:80774 tauroursodeoxycholic acid multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C031655 ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of ATF4 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of ATF4 mRNA] PMID:37207789|PMID:38845341 13884038 ATF4 activating transcription factor 4 gene CHEBI:9381 T-2 toxin increases expression EXP E RGD:6480464 20220308 CTD MESH:D013605 T-2 Toxin results in increased expression of ATF4 protein PMID:34637808 13884051 DDX28 DEAD-box helicase 28 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX28 mRNA PMID:35307453 13884057 PRR13 proline rich 13 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PRR13 mRNA PMID:35307453 13884127 POLR1A RNA polymerase I subunit A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of POLR1A mRNA PMID:35307453 13884179 KIAA1217 KIAA1217 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of KIAA1217 mRNA PMID:28069986 13884423 ACTN1 actinin alpha 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACTN1 mRNA PMID:35307453 13884463 POLR2M RNA polymerase II subunit M gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of POLR2M mRNA PMID:35307453 13884589 CA12 carbonic anhydrase 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CA12 mRNA PMID:35307453 13884589 CA12 carbonic anhydrase 12 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CA12 mRNA PMID:34389318 13884636 C2H11orf58 chromosome 2 C11orf58 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in increased expression of C2H11ORF58 mRNA PMID:35307453 13884645 GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GALNT5 mRNA PMID:35307453 13884715 CCT4 chaperonin containing TCP1 subunit 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCT4 mRNA PMID:35307453 13884738 ACTG2 actin gamma 2, smooth muscle gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACTG2 mRNA; deoxynivalenol results in decreased expression of ACTG2 protein PMID:38403181 13884761 FCSK fucose kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FCSK mRNA PMID:35307453 13884830 UBE2M ubiquitin conjugating enzyme E2 M gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBE2M mRNA PMID:35307453 13885110 HIRA histone cell cycle regulator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HIRA mRNA PMID:35307453 13885160 LRRC9 leucine rich repeat containing 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LRRC9 mRNA PMID:35307453 13885278 CASP9 caspase 9 gene CHEBI:10022 deoxynivalenol increases cleavage EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol results in increased cleavage of CASP9 protein PMID:38104654 13885278 CASP9 caspase 9 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20230307 CTD MESH:D008550 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein] PMID:35665993 13885278 CASP9 caspase 9 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA] PMID:36584959 13885278 CASP9 caspase 9 gene CHEBI:22977 cadmium atom increases activity EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased activity of CASP9 protein PMID:19135140 13885278 CASP9 caspase 9 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP9 mRNA; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of CASP9 protein]; Selenium inhibits the reaction [Cadmium results in increased activity of CASP9 protein] PMID:19135140|PMID:33493553|PMID:33891997 13885278 CASP9 caspase 9 gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012643 Selenium inhibits the reaction [Cadmium results in increased activity of CASP9 protein] PMID:19135140 13885278 CASP9 caspase 9 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of CASP9 mRNA PMID:36584959 13885278 CASP9 caspase 9 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA] PMID:36584959 13885278 CASP9 caspase 9 gene CHEBI:27899 cisplatin increases activity EXP E RGD:6480464 20191114 CTD MESH:D002945 Cisplatin results in increased activity of CASP9 protein PMID:20435919 13885278 CASP9 caspase 9 gene CHEBI:27899 cisplatin increases expression EXP E RGD:6480464 20191114 CTD MESH:D002945 Cisplatin results in increased expression of CASP9 PMID:12712633 13885278 CASP9 caspase 9 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of CASP9 protein] PMID:19135140|PMID:33905761 13885278 CASP9 caspase 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of CASP9 mRNA PMID:37108405 13885278 CASP9 caspase 9 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP9 mRNA] PMID:37108405 13885278 CASP9 caspase 9 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A increases expression EXP E RGD:6480464 20230307 CTD MESH:C020806 tetrabromobisphenol A results in increased expression of CASP9 mRNA; tetrabromobisphenol A results in increased expression of CASP9 protein PMID:35665993 13885278 CASP9 caspase 9 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C020806 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein] PMID:35665993 13885278 CASP9 caspase 9 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased expression of CASP9 protein PMID:26607349 13885278 CASP9 caspase 9 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP9 mRNA; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein] PMID:26607349|PMID:33493553|PMID:33891997 13885278 CASP9 caspase 9 gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012643 Selenium inhibits the reaction [Cadmium results in increased activity of CASP9 protein] PMID:19135140 13885278 CASP9 caspase 9 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20211012 CTD MESH:C056933 fumonisin B1 results in increased expression of CASP9 mRNA; fumonisin B1 results in increased expression of CASP9 protein; fumonisin B1 results in increased expression of CASP9 protein modified form PMID:33905761|PMID:36397609 13885278 CASP9 caspase 9 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C056933 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein modified form]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein modified form]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein] PMID:33905761|PMID:36397609 13885278 CASP9 caspase 9 gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D018038 Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP9 mRNA]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP9 protein] PMID:26607349|PMID:37108405 13885278 CASP9 caspase 9 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20211012 CTD MESH:C025589 ochratoxin A results in increased expression of CASP9 mRNA; ochratoxin A results in increased expression of CASP9 protein; ochratoxin A results in increased expression of CASP9 protein modified form PMID:33905761|PMID:36397609 13885278 CASP9 caspase 9 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C025589 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein modified form]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein modified form]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of CASP9 protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein] PMID:33905761|PMID:36397609 13885278 CASP9 caspase 9 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 mRNA]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein modified form]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of CASP9 protein] PMID:33905761 13885378 SHROOM1 shroom family member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SHROOM1 mRNA PMID:35307453 13885403 IGFBP5 insulin like growth factor binding protein 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IGFBP5 mRNA PMID:35307453 13885403 IGFBP5 insulin like growth factor binding protein 5 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of IGFBP5 mRNA PMID:34933075 13885403 IGFBP5 insulin like growth factor binding protein 5 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of IGFBP5 mRNA PMID:18988085 13885403 IGFBP5 insulin like growth factor binding protein 5 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of IGFBP5 mRNA PMID:21852083 13885490 NPG4 protegrin 4 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20210803 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of CAMP mRNA] PMID:21852083 13885511 ABHD8 abhydrolase domain containing 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABHD8 mRNA PMID:35307453 13885545 MROH1 maestro heat like repeat family member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MROH1 mRNA PMID:35307453 13885616 SLC6A20 solute carrier family 6 member 20 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC6A20 mRNA PMID:35307453 13885714 ARF2 ADP-ribosylation factor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARF2 mRNA PMID:35307453 13885744 LOC110255234 liver carboxylesterase-like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CES1 mRNA PMID:35307453 13885744 LOC110255234 liver carboxylesterase-like gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of CES1 mRNA PMID:34933075 13885744 LOC110255234 liver carboxylesterase-like gene CHEBI:64243 monosodium L-glutamate multiple interactions EXP E RGD:6480464 20200901 CTD MESH:D012970 Sodium Glutamate inhibits the reaction [Dietary Fats results in decreased expression of CES1 mRNA] PMID:31360149 13885853 SP6 Sp6 transcription factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SP6 mRNA PMID:35307453 13885891 SCML2 Scm polycomb group protein like 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of SCML2 mRNA PMID:21852083 13885919 ZBTB11 zinc finger and BTB domain containing 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZBTB11 mRNA PMID:35307453 13886100 HOXB2 homeobox B2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HOXB2 mRNA PMID:35307453 13886467 BCAS1 brain enriched myelin associated protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BCAS1 mRNA PMID:35307453 13886538 GLYCTK glycerate kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GLYCTK mRNA PMID:35307453 13886591 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene CHEBI:27485 prostaglandin J2 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C037112 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA] PMID:11889176 13886591 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene CHEBI:41879 dexamethasone increases expression EXP E RGD:6480464 20191114 CTD MESH:D003907 Dexamethasone results in increased expression of CYP17A1 PMID:19852296 13886591 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene CHEBI:47136 pentachlorobenzene increases expression EXP E RGD:6480464 20191114 CTD MESH:C003060 pentachlorobenzene results in increased expression of CYP17A1 protein PMID:21296658 13886591 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene CHEBI:5692 hexachlorobenzene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D006581 Hexachlorobenzene results in decreased expression of CYP17A1 protein PMID:21296658 13886591 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 protein modified form] PMID:11889176 13886729 RNF39 ring finger protein 39 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RNF39 mRNA PMID:35307453 13886777 BPIFB4 BPI fold containing family B member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BPIFB4 mRNA PMID:35307453 13886816 LTF lactotransferrin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LTF mRNA PMID:35307453 13886816 LTF lactotransferrin gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of PLF mRNA PMID:18988085 13886842 RIMKLA ribosomal modification protein rimK like family member A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RIMKLA mRNA PMID:35307453 13887025 PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDP2 mRNA PMID:35307453 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAPK3 mRNA; deoxynivalenol results in decreased expression of MAPK3 protein modified form PMID:26988607|PMID:35307453 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:10022 deoxynivalenol increases activity EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased activity of MAPK3 protein PMID:19674540 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:10022 deoxynivalenol increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol analog results in increased phosphorylation of MAPK3 protein; deoxynivalenol results in increased phosphorylation of MAPK3 protein PMID:22859312 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:135697 sarpogrelate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C064294 sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein] PMID:11426759 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C028451 3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK3 protein PMID:20406653 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C028451 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK3 protein] PMID:20406653 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16240 hydrogen peroxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein PMID:11325585|PMID:21798251 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] PMID:21798251 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16412 lipopolysaccharide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased phosphorylation of MAPK3 protein PMID:28528741 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008070 ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] PMID:28528741 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of MAPK3 mRNA PMID:32423882 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:17688 (S)-nicotine decreases phosphorylation EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased phosphorylation of MAPK3 protein PMID:32423882 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of MAPK3 mRNA PMID:32423882 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:18723 nicotine decreases phosphorylation EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased phosphorylation of MAPK3 protein PMID:32423882 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:207229 dihydroartemisinin decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C039060 artenimol results in decreased phosphorylation of MAPK3 protein PMID:29309768 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein PMID:10356984 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:27915 melamine increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C011907 melamine results in increased phosphorylation of MAPK3 protein PMID:30055240 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:2825 aristolochic acid A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C000228 aristolochic acid I results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [aristolochic acid I results in increased phosphorylation of and results in increased activity of MAPK3 protein] PMID:21658425 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:28790 serotonin increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D012701 Serotonin results in increased phosphorylation of MAPK3 protein PMID:11426759 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:28790 serotonin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012701 sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein] PMID:11426759 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:3093 bifenthrin increases phosphorylation EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin results in increased phosphorylation of MAPK3 protein PMID:33901951 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:32234 titanium dioxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C009495 titanium dioxide results in increased phosphorylation of MAPK3 protein PMID:23380242 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C023035 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein PMID:20406653 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:37537 phorbol 13-acetate 12-myristate increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein PMID:11325585 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:38221 fumonisin B1 increases phosphorylation EXP E RGD:6480464 20200211 CTD MESH:C056933 fumonisin B1 results in increased phosphorylation of MAPK3 protein PMID:31557363 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:39329 etoxazole increases phosphorylation EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole results in increased phosphorylation of MAPK3 protein PMID:31744678 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:39329 etoxazole multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C508136 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein] PMID:31744678 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:48843 disodium selenite increases expression EXP E RGD:6480464 20191114 CTD MESH:D018038 Sodium Selenite results in increased expression of MAPK3 protein PMID:17342738 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:5078 flavonol increases expression EXP E RGD:6480464 20191114 CTD MESH:C041477 3-hydroxyflavone results in increased expression of MAPK3 protein PMID:21126572 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:50842 norflurazon decreases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased phosphorylation of MAPK3 protein PMID:38432436 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D007559 pyrazolanthrone inhibits the reaction [Ivermectin results in decreased phosphorylation of MAPK3 protein]; U 0126 promotes the reaction [Ivermectin results in decreased phosphorylation of MAPK3 protein] PMID:31400776 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:65329 LY294002 multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C085911 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein PMID:31744678 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:68889 hydroxytyrosol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C005975 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] PMID:21798251 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:7719 ochratoxin A increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased phosphorylation of MAPK3 protein PMID:28699257 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] PMID:28528741 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:8228 pioglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C060836 Pioglitazone promotes the reaction [Troglitazone results in increased phosphorylation of MAPK3 protein] PMID:17065204 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C432165 [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; pyrazolanthrone inhibits the reaction [Ivermectin results in decreased phosphorylation of MAPK3 protein] PMID:31400776|PMID:31744678 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C093642 SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein] PMID:31744678 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:9753 troglitazone increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone results in increased phosphorylation of MAPK3 protein PMID:17065204 13887126 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 Pioglitazone promotes the reaction [Troglitazone results in increased phosphorylation of MAPK3 protein] PMID:17065204 13887195 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HMGCR mRNA PMID:35307453 13887195 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene CHEBI:49040 ezetimibe increases expression EXP E RGD:6480464 20191114 CTD MESH:D000069438 Ezetimibe results in increased expression of HMGCR mRNA PMID:17130282 13887195 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene CHEBI:49040 ezetimibe multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069438 Simvastatin promotes the reaction [Ezetimibe results in increased expression of HMGCR mRNA] PMID:17130282 13887195 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene CHEBI:9150 simvastatin decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019821 Simvastatin results in decreased expression of HMGCR mRNA PMID:19343539 13887195 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene CHEBI:9150 simvastatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019821 Simvastatin promotes the reaction [Ezetimibe results in increased expression of HMGCR mRNA] PMID:17130282 13887235 PARM1 prostate androgen-regulated mucin-like protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PARM1 mRNA PMID:35307453 13887243 TGFBR1 transforming growth factor beta receptor 1 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in increased expression of TGFBR1 mRNA PMID:33626375 13887525 COLGALT2 collagen beta(1-O)galactosyltransferase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COLGALT2 mRNA PMID:35307453 13887525 COLGALT2 collagen beta(1-O)galactosyltransferase 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of COLGALT2 mRNA PMID:34933075 13887600 UBXN11 UBX domain protein 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UBXN11 mRNA PMID:35307453 13887719 CYP39A1 cytochrome P450 family 39 subfamily A member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP39A1 mRNA PMID:35307453 13887811 MOBKL3 MOB family member 4, phocein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MOBKL3 mRNA PMID:35307453 13887878 MMP12 matrix metallopeptidase 12 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MMP12 mRNA PMID:35307453 13887971 ADIG adipogenin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADIG mRNA PMID:35307453 13888401 DNAH7 dynein axonemal heavy chain 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAH7 mRNA PMID:35307453 13888510 CHDH choline dehydrogenase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CHDH mRNA PMID:35307453 13888563 PUM3 pumilio RNA binding family member 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PUM3 mRNA PMID:35307453 13888629 THOP1 thimet oligopeptidase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of THOP1 mRNA PMID:35307453 13888669 PRSS56 serine protease 56 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRSS56 mRNA PMID:35307453 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NQO1 mRNA PMID:35307453 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:10106 zearalenone affects expression EXP E RGD:6480464 20200519 CTD MESH:D015025 Zearalenone affects the expression of NQO1 mRNA; Zearalenone affects the expression of NQO1 protein PMID:31760079 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20221206 CTD MESH:D015025 Zearalenone results in decreased expression of NQO1 mRNA; Zearalenone results in decreased expression of NQO1 protein PMID:35489465 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20221206 CTD MESH:D015025 [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein] PMID:35489465 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA] PMID:36584959 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NQO1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NQO1 mRNA PMID:33493553|PMID:34416349 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:26267 proanthocyanidin multiple interactions EXP E RGD:6480464 20221206 CTD MESH:D044945 [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of NQO1 protein] PMID:35489465 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of NQO1 mRNA PMID:31677563|PMID:35388968|PMID:36584959 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA] PMID:36584959 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of NQO1 mRNA; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of NQO1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of NQO1 protein] PMID:21852083|PMID:37955343 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002945 Dicumarol inhibits the reaction [sulforaphane inhibits the reaction [Cisplatin results in decreased activity of NQO1 protein]]; sulforaphane inhibits the reaction [Cisplatin results in decreased activity of NQO1 protein] PMID:20732396 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl increases expression EXP E RGD:6480464 20191114 CTD MESH:C023035 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA PMID:24709675 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C023035 [epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NQO1 mRNA; CAV1 mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] PMID:22521609|PMID:24709675 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:35456 cadmium dichloride decreases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in decreased expression of NQO1 mRNA PMID:33626375 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NQO1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NQO1 mRNA PMID:33493553|PMID:34416349 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20240604 CTD MESH:C056933 fumonisin B1 results in decreased expression of NQO1 mRNA; fumonisin B1 results in decreased expression of NQO1 protein PMID:37955343 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C056933 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of NQO1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of NQO1 protein] PMID:37955343 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:4513 dicoumarol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001728 Dicumarol inhibits the reaction [sulforaphane inhibits the reaction [Cisplatin results in decreased activity of NQO1 protein]] PMID:20732396 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:47807 sulforaphane increases activity EXP E RGD:6480464 20191114 CTD MESH:C016766 sulforaphane results in increased activity of NQO1 protein PMID:20732396 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:47807 sulforaphane increases expression EXP E RGD:6480464 20191114 CTD MESH:C016766 sulforaphane results in increased expression of NQO1 protein PMID:28710020 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:47807 sulforaphane multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C016766 Dicumarol inhibits the reaction [sulforaphane inhibits the reaction [Cisplatin results in decreased activity of NQO1 protein]]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of NQO1 protein]; sulforaphane inhibits the reaction [Cisplatin results in decreased activity of NQO1 protein] PMID:20732396|PMID:28710020 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate increases expression EXP E RGD:6480464 20191114 CTD MESH:C045651 epigallocatechin gallate results in increased expression of NQO1 mRNA PMID:22521609 13888687 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C045651 [epigallocatechin gallate co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [epigallocatechin gallate results in increased expression of NQO1 mRNA] PMID:22521609 13889038 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PACSIN1 mRNA PMID:35307453 13889180 ATG4A autophagy related 4A cysteine peptidase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATG4A mRNA PMID:35307453 13889310 GNAO1 G protein subunit alpha o1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of GNAO1 mRNA PMID:34933075 13889335 ACTRT3 actin related protein T3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACTRT3 mRNA PMID:35307453 13889467 INSYN1 inhibitory synaptic factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of INSYN1 mRNA PMID:35307453 13889474 BST2 bone marrow stromal cell antigen 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BST2 mRNA PMID:35307453 13889480 CUL7 cullin 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CUL7 mRNA PMID:35307453 13889669 HOXA9 homeobox A9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HOXA9 mRNA PMID:35307453 13889779 SLC4A11 solute carrier family 4 member 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC4A11 mRNA PMID:35307453 13889863 COX10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of COX10 mRNA PMID:35307453 13889931 HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HPS1 mRNA PMID:35307453 13889984 SLC16A12 solute carrier family 16 member 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC16A12 mRNA PMID:35307453 13889984 SLC16A12 solute carrier family 16 member 12 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of SLC16A12 mRNA PMID:34933075 13890082 NID2 nidogen 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NID2 mRNA PMID:35307453 13890243 HTRA1 HtrA serine peptidase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HTRA1 mRNA PMID:35307453 13890243 HTRA1 HtrA serine peptidase 1 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of HTRA1 mRNA PMID:28069986 13890451 CHEK1 checkpoint kinase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CHEK1 mRNA PMID:35307453 13890601 MTMR2 myotubularin related protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MTMR2 mRNA PMID:35307453 13890641 EIF4H eukaryotic translation initiation factor 4H gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF4H mRNA PMID:35307453 13890653 DCAKD dephospho-CoA kinase domain containing gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DCAKD mRNA PMID:35307453 13890714 RRM2 ribonucleotide reductase regulatory subunit M2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RRM2 mRNA PMID:35307453 13890753 GJA4 gap junction protein alpha 4 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of GJA4 mRNA PMID:26386189 13890921 MESP2 mesoderm posterior bHLH transcription factor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MESP2 mRNA PMID:35307453 13890970 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in decreased expression of SDHA mRNA] PMID:37999554 13890970 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA] PMID:36584959 13890970 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of SDHA mRNA PMID:36584959 13890970 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA] PMID:36584959 13890970 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in decreased expression of SDHA mRNA PMID:37999554 13890970 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in decreased expression of SDHA mRNA] PMID:37999554 13890998 SEC16A SEC16 homolog A, endoplasmic reticulum export factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SEC16A mRNA PMID:35307453 13891049 STAM2 signal transducing adaptor molecule 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STAM2 mRNA PMID:35307453 13891116 FLNC filamin C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FLNC mRNA PMID:35307453 13891245 FGFR1 fibroblast growth factor receptor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FGFR1 mRNA PMID:35307453 13891245 FGFR1 fibroblast growth factor receptor 1 gene CHEBI:17026 progesterone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone results in decreased expression of FGFR1 mRNA alternative form PMID:15120423 13891245 FGFR1 fibroblast growth factor receptor 1 gene CHEBI:17026 progesterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011374 estrone benzoate inhibits the reaction [Progesterone results in decreased expression of FGFR1 mRNA alternative form] PMID:15120423 13891276 GPX2 glutathione peroxidase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of GPX2 mRNA PMID:25701311|PMID:35307453 13891276 GPX2 glutathione peroxidase 2 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 [Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA PMID:36584959 13891276 GPX2 glutathione peroxidase 2 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 [Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA PMID:36584959 13891276 GPX2 glutathione peroxidase 2 gene CHEBI:34631 chlorpyrifos decreases expression EXP E RGD:6480464 20231205 CTD MESH:D004390 Chlorpyrifos results in decreased expression of GPX2 mRNA PMID:34399389|PMID:38565334 13891389 TMEM106B transmembrane protein 106B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM106B mRNA PMID:35307453 13891411 SLC26A11 solute carrier family 26 member 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC26A11 mRNA PMID:35307453 13891432 PLAUR plasminogen activator, urokinase receptor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PLAUR mRNA PMID:35307453 13891432 PLAUR plasminogen activator, urokinase receptor gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of PLAUR mRNA PMID:18988085 13891432 PLAUR plasminogen activator, urokinase receptor gene CHEBI:46680 serpentine asbestos increases expression EXP E RGD:6480464 20201006 CTD MESH:D017632 Asbestos, Serpentine results in increased expression of PLAUR protein PMID:9853007 13891548 GPS2 G protein pathway suppressor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GPS2 mRNA PMID:35307453 13891656 TJP2 tight junction protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TJP2 mRNA PMID:35307453 13891656 TJP2 tight junction protein 2 gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of TJP2 protein PMID:37659622 13891656 TJP2 tight junction protein 2 gene CHEBI:146195 3-acetyldeoxynivalenol multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C043247 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in decreased expression of TJP2 protein] PMID:37659622 13891656 TJP2 tight junction protein 2 gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in decreased expression of TJP2 mRNA] PMID:37999554 13891656 TJP2 tight junction protein 2 gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of TJP2 protein PMID:36754226 13891656 TJP2 tight junction protein 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in decreased expression of TJP2 mRNA PMID:37999554 13891656 TJP2 tight junction protein 2 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in decreased expression of TJP2 mRNA] PMID:37999554 13891656 TJP2 tight junction protein 2 gene CHEBI:33709 amino acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000596 Amino Acids inhibits the reaction [Diquat results in decreased expression of TJP2 protein] PMID:26338884 13891656 TJP2 tight junction protein 2 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004178 Diquat results in decreased expression of TJP2 protein PMID:26338884 13891656 TJP2 tight junction protein 2 gene CHEBI:64163 diquat multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004178 Amino Acids inhibits the reaction [Diquat results in decreased expression of TJP2 protein] PMID:26338884 13891656 TJP2 tight junction protein 2 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D020123 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in decreased expression of TJP2 protein] PMID:37659622 13891830 ALDH3B1 aldehyde dehydrogenase 3 family member B1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALDH3B1 mRNA PMID:35307453 13891977 SPR sepiapterin reductase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPR mRNA PMID:35307453 13892007 NME1 NME/NM23 nucleoside diphosphate kinase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NME1 mRNA PMID:35307453 13892050 FAT1 FAT atypical cadherin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAT1 mRNA PMID:35307453 13892215 PTPN13 protein tyrosine phosphatase non-receptor type 13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTPN13 mRNA; deoxynivalenol results in decreased expression of PTPN13 protein PMID:38403181 13892279 TREX1 three prime repair exonuclease 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TREX1 mRNA PMID:35307453 13892319 ENO3 enolase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENO3 mRNA PMID:35307453 13892392 UBA3 ubiquitin like modifier activating enzyme 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBA3 mRNA PMID:35307453 13892425 RASAL1 RAS protein activator like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RASAL1 mRNA PMID:35307453 13892539 ACOT9 acyl-CoA thioesterase 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACOT9 mRNA PMID:35307453 13892586 C2CD4C C2 calcium dependent domain containing 4C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C2CD4C mRNA PMID:35307453 13892597 SLC22A2 solute carrier family 22 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC22A2 mRNA PMID:35307453 13892597 SLC22A2 solute carrier family 22 member 2 gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] PMID:19605544 13892597 SLC22A2 solute carrier family 22 member 2 gene CHEBI:28527 rutin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012431 Rutin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] PMID:19605544 13892597 SLC22A2 solute carrier family 22 member 2 gene CHEBI:44296 tetraethylammonium increases uptake EXP E RGD:6480464 20191114 CTD MESH:D019789 SLC22A2 protein results in increased uptake of Tetraethylammonium PMID:19605544 13892597 SLC22A2 solute carrier family 22 member 2 gene CHEBI:44296 tetraethylammonium multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019789 Quercetin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Rutin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] PMID:19605544 13892781 GJA10 gap junction protein alpha 10 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of GJA10 mRNA PMID:21852083 13892940 ARK2N arkadia (RNF111) N-terminal like PKA signaling regulator 2N gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230404 CTD MESH:C007262 deoxynivalenol results in increased expression of ARK2N mRNA PMID:35307453 13892987 DNPEP aspartyl aminopeptidase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DNPEP mRNA PMID:35307453 13893144 TWNK twinkle mtDNA helicase gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TWNK mRNA PMID:33592257 13893144 TWNK twinkle mtDNA helicase gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TWNK mRNA PMID:33592257 13893267 SF3A3 splicing factor 3a subunit 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SF3A3 mRNA PMID:35307453 13893336 FAAH2 fatty acid amide hydrolase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAAH2 mRNA PMID:35307453 13893425 CRY1 cryptochrome circadian regulator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CRY1 mRNA PMID:35307453 13893471 ZIC2 Zic family member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZIC2 mRNA PMID:35307453 13893559 OSER1 oxidative stress responsive serine rich 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of OSER1 mRNA PMID:35307453 13893637 SYNE3 spectrin repeat containing nuclear envelope family member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SYNE3 mRNA PMID:35307453 13893660 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADAMTS9 mRNA PMID:35307453 13893735 L3MBTL2 L3MBTL histone methyl-lysine binding protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of L3MBTL2 mRNA PMID:35307453 13894014 WDR20 WD repeat domain 20 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of WDR20 mRNA PMID:35307453 13894015 SLC26A6 solute carrier family 26 member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC26A6 mRNA PMID:35307453 13894361 GAB1 GRB2 associated binding protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GAB1 mRNA PMID:35307453 13894533 B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of B3GNT3 mRNA PMID:35307453 13894575 ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZRSR2 mRNA PMID:35307453 13894618 MRPS5 mitochondrial ribosomal protein S5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS5 mRNA PMID:35307453 13894643 ADGRL3 adhesion G protein-coupled receptor L3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADGRL3 mRNA PMID:35307453 13894680 CARF calcium responsive transcription factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CARF mRNA PMID:35307453 13894734 ATRAID all-trans retinoic acid induced differentiation factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATRAID mRNA PMID:35307453 13894778 KIAA1143 KIAA1143 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KIAA1143 mRNA PMID:35307453 13894899 MAFK MAF bZIP transcription factor K gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MAFK mRNA PMID:35307453 13894955 PNPLA4 patatin like phospholipase domain containing 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PNPLA4 mRNA PMID:35307453 13895075 ZNF529 zinc finger protein 529 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF461 mRNA PMID:35307453 13895089 MYH11 myosin heavy chain 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYH11 mRNA PMID:38403181 13895089 MYH11 myosin heavy chain 11 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of MYH11 mRNA PMID:34933075 13895135 ETV3 ETS variant transcription factor 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ETV3 mRNA PMID:35307453 13895162 EMG1 EMG1 N1-specific pseudouridine methyltransferase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EMG1 mRNA PMID:35307453 13895188 SEMA6D semaphorin 6D gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SEMA6D mRNA PMID:35307453 13895346 PCBP1 poly(rC) binding protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PCBP1 mRNA PMID:35307453 13895464 TDRD6 tudor domain containing 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TDRD6 mRNA PMID:35307453 13895940 MLXIP MLX interacting protein gene CHEBI:17234 glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of MLXIP mRNA PMID:25827716 13895940 MLXIP MLX interacting protein gene CHEBI:17234 glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] PMID:25827716 13895940 MLXIP MLX interacting protein gene CHEBI:17634 D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of MLXIP mRNA PMID:25827716 13895940 MLXIP MLX interacting protein gene CHEBI:17634 D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] PMID:25827716 13895940 MLXIP MLX interacting protein gene CHEBI:42758 aldehydo-D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of MLXIP mRNA PMID:25827716 13895940 MLXIP MLX interacting protein gene CHEBI:42758 aldehydo-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] PMID:25827716 13895965 HPSE heparanase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HPSE mRNA PMID:35307453 13895981 LIF LIF interleukin 6 family cytokine gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of LIF mRNA PMID:37706587 13895981 LIF LIF interleukin 6 family cytokine gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of LIF mRNA] PMID:37706587 13895981 LIF LIF interleukin 6 family cytokine gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of LIF mRNA] PMID:21852083 13895981 LIF LIF interleukin 6 family cytokine gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of LIF mRNA] PMID:37706587 13896058 UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UMAD1 mRNA PMID:35307453 13896186 GRWD1 glutamate rich WD repeat containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GRWD1 mRNA; deoxynivalenol results in increased expression of GRWD1 protein PMID:35307453|PMID:38403181 13896282 POLR3G RNA polymerase III subunit G gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of POLR3G mRNA PMID:35307453 13896305 PDE7B phosphodiesterase 7B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PDE7B mRNA PMID:35307453 13896339 SC5D sterol-C5-desaturase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SC5D mRNA PMID:35307453 13896348 S100B S100 calcium binding protein B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100B mRNA PMID:35307453 13896446 HKDC1 hexokinase domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HKDC1 mRNA PMID:35307453 13896824 CRYBG3 crystallin beta-gamma domain containing 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CRYBG3 mRNA PMID:35307453 13896886 MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MICAL1 mRNA PMID:35307453 13896932 RRS1 ribosome biogenesis regulator 1 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RRS1 mRNA PMID:35307453 13897010 IDUA alpha-L-iduronidase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IDUA mRNA PMID:35307453 13897090 RPP38 ribonuclease P/MRP subunit p38 gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of RPP38 mRNA PMID:32423882 13897090 RPP38 ribonuclease P/MRP subunit p38 gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of RPP38 mRNA PMID:32423882 13897107 TSGA10 testis specific 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TSGA10 mRNA PMID:35307453 13897192 SLC10A2 solute carrier family 10 member 2 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of SLC10A2 mRNA PMID:35307453 13897289 RXRB retinoid X receptor beta gene CHEBI:39329 etoxazole decreases expression EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole results in decreased expression of RXRB mRNA PMID:31744678 13897403 SLC44A4 solute carrier family 44 member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC44A4 mRNA PMID:35307453 13897440 PGAM1 phosphoglycerate mutase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PGAM1 mRNA PMID:35307453 13897554 FAT2 FAT atypical cadherin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAT2 mRNA PMID:35307453 13897582 PMPCB peptidase, mitochondrial processing subunit beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PMPCB mRNA PMID:35307453 13897648 MTURN maturin, neural progenitor differentiation regulator homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MTURN mRNA PMID:35307453 13897661 MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MICAL2 mRNA PMID:35307453 13897714 BMX BMX non-receptor tyrosine kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BMX mRNA PMID:35307453 13897826 KLF4 KLF transcription factor 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KLF4 mRNA PMID:35307453 13897877 RPUSD3 RNA pseudouridine synthase D3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RPUSD3 mRNA PMID:35307453 13897897 DDX17 DEAD-box helicase 17 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of DDX17 mRNA; Resveratrol promotes the reaction [Dietary Fats results in decreased expression of DDX17 mRNA] PMID:21852083 13898115 UTP23 UTP23 small subunit processome component gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UTP23 mRNA PMID:35307453 13898182 VSTM2L V-set and transmembrane domain containing 2 like gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of VSTM2L mRNA PMID:34933075 13898190 BMP15 bone morphogenetic protein 15 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of BMP15 mRNA PMID:26386189 13898190 BMP15 bone morphogenetic protein 15 gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015025 Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of BMP15 mRNA] PMID:26386189 13898190 BMP15 bone morphogenetic protein 15 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of BMP15 mRNA] PMID:26386189 13898196 SCARF1 scavenger receptor class F member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCARF1 mRNA PMID:35307453 13898332 SELENOO selenoprotein O gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SELENOO mRNA PMID:35307453 13898374 DSTN destrin, actin depolymerizing factor gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of DSTN mRNA PMID:21852083 13898409 CLK3 CDC like kinase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CLK3 mRNA PMID:35307453 13898541 ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACAP1 mRNA PMID:35307453 13898726 HPGD 15-hydroxyprostaglandin dehydrogenase gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of HPGD mRNA PMID:34389318 13898761 SMYD5 SMYD family member 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMYD5 mRNA PMID:35307453 13898851 PGM3 phosphoglucomutase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PGM3 mRNA PMID:35307453 13898907 CYP4F22 cytochrome P450 family 4 subfamily F member 22 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of CYP4F22 mRNA PMID:34933075 13898943 SLC13A4 solute carrier family 13 member 4 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of SLC13A4 mRNA PMID:34389318 13899026 C10H1orf115 chromosome 10 C1orf115 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C10H1ORF115 mRNA PMID:35307453 13899032 SMG9 SMG9 nonsense mediated mRNA decay factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMG9 mRNA; deoxynivalenol results in increased expression of SMG9 protein PMID:35307453|PMID:38403181 13899124 FBXO15 F-box protein 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FBXO15 mRNA PMID:35307453 13899188 TPRA1 transmembrane protein adipocyte associated 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TPRA1 mRNA PMID:35307453 13899246 NT5M 5',3'-nucleotidase, mitochondrial gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NT5M mRNA PMID:35307453 13899500 CLCN4 chloride voltage-gated channel 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLCN4 mRNA PMID:35307453 13899565 MTA2 metastasis associated 1 family member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MTA2 mRNA PMID:35307453 13899613 ROM1 retinal outer segment membrane protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ROM1 mRNA PMID:35307453 13899666 TXLNG taxilin gamma gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TXLNG mRNA PMID:35307453 13900101 NAV2 neuron navigator 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NAV2 mRNA PMID:35307453 13900376 PEAK1 pseudopodium enriched atypical kinase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PEAK1 mRNA PMID:35307453 13900403 GLI2 GLI family zinc finger 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of GLI2 mRNA PMID:34933075 13900403 GLI2 GLI family zinc finger 2 gene CHEBI:29224 dibromine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in decreased expression of GLI2 mRNA PMID:21391292 13900528 FUZ fuzzy planar cell polarity protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FUZ mRNA PMID:35307453 13900548 EIF3A eukaryotic translation initiation factor 3 subunit A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF3A mRNA PMID:35307453 13900625 IL13 interleukin 13 gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased expression of IL13 mRNA PMID:15998543 13900625 IL13 interleukin 13 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL13 mRNA PMID:33891997 13900625 IL13 interleukin 13 gene CHEBI:28640 lipoteichoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:C009900 lipoteichoic acid results in increased expression of IL13 mRNA PMID:15998543 13900625 IL13 interleukin 13 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL13 mRNA PMID:33891997 13900795 GNL2 G protein nucleolar 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GNL2 mRNA PMID:35307453 13900850 GSE1 Gse1 coiled-coil protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GSE1 mRNA PMID:35307453 13900905 EFNA3 ephrin A3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EFNA3 mRNA PMID:35307453 13900973 RHOA ras homolog family member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of RHOA mRNA PMID:38403181 13901014 CHSY1 chondroitin sulfate synthase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CHSY1 mRNA PMID:35307453 13901020 RAD54B RAD54 homolog B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAD54B mRNA PMID:35307453 13901047 ARHGAP45 Rho GTPase activating protein 45 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARHGAP45 mRNA PMID:35307453 13901113 ZNF432 zinc finger protein 432 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF432 mRNA PMID:35307453 13901221 DNMT3B DNA methyltransferase 3 beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNMT3B mRNA PMID:35307453 13901221 DNMT3B DNA methyltransferase 3 beta gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of DNMT3B mRNA PMID:28819136 13901287 SEC31A SEC31 homolog A, COPII coat complex component gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SEC31A mRNA PMID:35307453 13901792 PTPN4 protein tyrosine phosphatase non-receptor type 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTPN4 mRNA PMID:35307453 13901832 DYNLRB2 dynein light chain roadblock-type 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DYNLRB2 mRNA PMID:35307453 13901861 OSBPL5 oxysterol binding protein like 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of OSBPL5 mRNA; deoxynivalenol results in decreased expression of OSBPL5 protein PMID:38403181 13901945 RIOK3 RIO kinase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RIOK3 mRNA PMID:35307453 13901972 AQP9 aquaporin 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AQP9 mRNA PMID:35307453 13901972 AQP9 aquaporin 9 gene CHEBI:33216 bisphenol A affects expression EXP E RGD:6480464 20210406 CTD MESH:C006780 bisphenol A affects the expression of AQP9 mRNA PMID:32710935 13902102 NHSL2 NHS like 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of NHSL2 mRNA PMID:34933075 13902114 SPATA6 spermatogenesis associated 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPATA6 mRNA PMID:35307453 13902300 COL7A1 collagen type VII alpha 1 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL7A1 mRNA PMID:38403181 13902510 RADIL Rap associating with DIL domain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RADIL mRNA PMID:35307453 13902580 PDAP1 PDGFA associated protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDAP1 mRNA PMID:35307453 13902644 BEX3 brain expressed X-linked 3 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of BEX3 mRNA] PMID:21852083 13902749 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DHTKD1 mRNA PMID:35307453 13902885 LEP leptin gene CHEBI:16469 17beta-estradiol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased expression of LEP mRNA PMID:23153703 13902885 LEP leptin gene CHEBI:16469 17beta-estradiol increases secretion EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased secretion of LEP protein PMID:23153703 13902885 LEP leptin gene CHEBI:17026 progesterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone results in increased expression of LEP mRNA PMID:23153703 13902885 LEP leptin gene CHEBI:17026 progesterone increases secretion EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone results in increased secretion of LEP protein PMID:23153703 13902885 LEP leptin gene CHEBI:17026 progesterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011374 [TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone PMID:22151798 13902885 LEP leptin gene CHEBI:44658 okadaic acid affects expression EXP E RGD:6480464 20191114 CTD MESH:D019319 Okadaic Acid affects the expression of LEP mRNA PMID:10628429 13902912 COL18A1 collagen type XVIII alpha 1 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL18A1 mRNA; deoxynivalenol results in decreased expression of COL18A1 protein PMID:38403181 13902999 IFT122 intraflagellar transport 122 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFT122 mRNA PMID:35307453 13903100 COPB1 COPI coat complex subunit beta 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of COPB1 mRNA PMID:35307453 13903246 NOTCH1 notch receptor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NOTCH1 mRNA PMID:35307453 13903246 NOTCH1 notch receptor 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of NOTCH1 mRNA PMID:34933075 13903325 LOC110256483 carbonyl reductase [NADPH] 1-like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CBR1 mRNA PMID:35307453 13903325 LOC110256483 carbonyl reductase [NADPH] 1-like gene CHEBI:18009 NADP(+) affects binding EXP E RGD:6480464 20210803 CTD MESH:D009249 NADP binds to CBR1 protein PMID:15145449 13903325 LOC110256483 carbonyl reductase [NADPH] 1-like gene CHEBI:18009 NADP(+) multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D009249 NADP inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of CBR1 protein] PMID:15145449 13903325 LOC110256483 carbonyl reductase [NADPH] 1-like gene CHEBI:44409 NADP zwitterion affects binding EXP E RGD:6480464 20210803 CTD MESH:D009249 NADP binds to CBR1 protein PMID:15145449 13903325 LOC110256483 carbonyl reductase [NADPH] 1-like gene CHEBI:44409 NADP zwitterion multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D009249 NADP inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of CBR1 protein] PMID:15145449 13903476 MBNL2 muscleblind like splicing regulator 2 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of MBNL2 mRNA PMID:34389318 13903538 SERPINE1 serpin family E member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SERPINE1 mRNA PMID:35307453|PMID:37257635 13903538 SERPINE1 serpin family E member 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 protein PMID:34416349 13903538 SERPINE1 serpin family E member 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of SERPINE1 mRNA PMID:27617619 13903538 SERPINE1 serpin family E member 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of SERPINE1 mRNA PMID:21852083 13903538 SERPINE1 serpin family E member 1 gene CHEBI:2814 arecoline increases expression EXP E RGD:6480464 20191114 CTD MESH:D001115 Arecoline results in increased expression of SERPINE1 protein PMID:26908192 13903538 SERPINE1 serpin family E member 1 gene CHEBI:2814 arecoline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001115 pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of SERPINE1 protein] PMID:26908192 13903538 SERPINE1 serpin family E member 1 gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of SERPINE1 mRNA PMID:21391292 13903538 SERPINE1 serpin family E member 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 protein PMID:34416349 13903538 SERPINE1 serpin family E member 1 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of SERPINE1 protein] PMID:26908192 13903685 ST14 ST14 transmembrane serine protease matriptase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ST14 mRNA PMID:35307453 13903714 PGR progesterone receptor gene CHEBI:16469 17beta-estradiol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased expression of PGR mRNA PMID:16431846 13903772 MYBBP1A MYB binding protein 1a gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MYBBP1A mRNA PMID:35307453 13903772 MYBBP1A MYB binding protein 1a gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of MYBBP1A mRNA PMID:34389318 13903868 SLC31A2 solute carrier family 31 member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC31A2 mRNA PMID:35307453 13904010 SEMA3G semaphorin 3G gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SEMA3G mRNA PMID:35307453 13904037 FBXO39 F-box protein 39 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FBXO39 mRNA PMID:35307453 13904100 LDHA lactate dehydrogenase A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LDHA mRNA PMID:35307453 13904100 LDHA lactate dehydrogenase A gene CHEBI:15354 choline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002794 [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter PMID:29065941 13904100 LDHA lactate dehydrogenase A gene CHEBI:16170 mercury(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury binds to and results in decreased folding of LDHA protein PMID:18501191 13904100 LDHA lactate dehydrogenase A gene CHEBI:16240 hydrogen peroxide increases activity EXP E RGD:6480464 20240903 CTD MESH:D006861 Hydrogen Peroxide results in increased activity of LDHA protein PMID:38438008 13904100 LDHA lactate dehydrogenase A gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240903 CTD MESH:D006861 SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased activity of LDHA protein]; theanine inhibits the reaction [Hydrogen Peroxide results in increased activity of LDHA protein] PMID:38438008 13904100 LDHA lactate dehydrogenase A gene CHEBI:17394 N(5)-ethyl-L-glutamine multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C026166 theanine inhibits the reaction [Hydrogen Peroxide results in increased activity of LDHA protein] PMID:38438008 13904100 LDHA lactate dehydrogenase A gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001622 [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter PMID:29065941 13904100 LDHA lactate dehydrogenase A gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA mRNA; Cadmium binds to and results in decreased folding of LDHA protein PMID:18501191|PMID:34416349 13904100 LDHA lactate dehydrogenase A gene CHEBI:25195 mercury atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury binds to and results in decreased folding of LDHA protein PMID:18501191 13904100 LDHA lactate dehydrogenase A gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of LDHA mRNA PMID:18988085 13904100 LDHA lactate dehydrogenase A gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005492 [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter PMID:29065941 13904100 LDHA lactate dehydrogenase A gene CHEBI:27889 lead(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007854 Lead binds to and results in decreased folding of LDHA protein PMID:18501191 13904100 LDHA lactate dehydrogenase A gene CHEBI:33216 bisphenol A decreases methylation EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased methylation of LDHA promoter PMID:29065941 13904100 LDHA lactate dehydrogenase A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of LDHA mRNA PMID:29065941 13904100 LDHA lactate dehydrogenase A gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006780 [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter PMID:29065941 13904100 LDHA lactate dehydrogenase A gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA mRNA PMID:34416349 13904100 LDHA lactate dehydrogenase A gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C093642 SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased activity of LDHA protein] PMID:38438008 13904255 SDHAF3 succinate dehydrogenase complex assembly factor 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SDHAF3 mRNA PMID:35307453 13904265 UBE2D4 ubiquitin conjugating enzyme E2 D4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UBE2D4 mRNA PMID:35307453 13904279 KCNK7 potassium two pore domain channel subfamily K member 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KCNK7 mRNA PMID:35307453 13904434 AQP4 aquaporin 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20210406 CTD MESH:C006780 bisphenol A results in decreased expression of AQP4 mRNA PMID:32710935 13904475 PCSK4 proprotein convertase subtilisin/kexin type 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCSK4 mRNA PMID:35307453 13904501 CFAP119 cilia and flagella associated protein 119 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230404 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP119 mRNA PMID:35307453 13904674 AKAP12 A-kinase anchoring protein 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AKAP12 mRNA PMID:35307453 13904918 RAPGEF4 Rap guanine nucleotide exchange factor 4 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of RAPGEF4 mRNA PMID:18988085 13904965 TMSB10 thymosin beta 10 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of TMSB10 mRNA PMID:21852083 13904972 DLX1 distal-less homeobox 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DLX1 mRNA PMID:35307453 13905099 SERBP1 SERPINE1 mRNA binding protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SERBP1 mRNA PMID:35307453 13905134 SPEG striated muscle enriched protein kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPEG mRNA PMID:35307453 13905179 COPZ2 COPI coat complex subunit zeta 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COPZ2 mRNA PMID:35307453 13905267 ADCYAP1R1 ADCYAP receptor type I gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of ADCYAP1R1 mRNA PMID:34933075 13905267 ADCYAP1R1 ADCYAP receptor type I gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 [Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1R1 protein PMID:28506824 13905267 ADCYAP1R1 ADCYAP receptor type I gene CHEBI:16526 carbon dioxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002245 [Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1R1 protein PMID:28506824 13905267 ADCYAP1R1 ADCYAP receptor type I gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009538 Nicotine results in decreased expression of ADCYAP1R1 protein PMID:28506824 13905267 ADCYAP1R1 ADCYAP receptor type I gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009538 Nicotine results in decreased expression of ADCYAP1R1 protein PMID:28506824 13905467 BPIFC BPI fold containing family C gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of BPIFC mRNA PMID:34933075 13905556 SLC6A17 solute carrier family 6 member 17 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC6A17 mRNA PMID:35307453 13905671 IFN-ALPHA-15 interferon-alpha-15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFN-ALPHA-15 mRNA PMID:35307453 13905674 GTF3C4 general transcription factor IIIC subunit 4 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of GTF3C4 mRNA PMID:25455459 13905688 SLC27A4 solute carrier family 27 member 4 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20210706 CTD MESH:C056933 fumonisin B1 results in decreased expression of SLC27A4 mRNA PMID:33443779 13905803 GHRH growth hormone releasing hormone gene CHEBI:23414 copper(II) sulfate increases expression EXP E RGD:6480464 20191114 CTD MESH:D019327 Copper Sulfate results in increased expression of GHRH mRNA PMID:21110139 13905840 AP1M2 adaptor related protein complex 1 subunit mu 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AP1M2 mRNA PMID:35307453 13906019 COL16A1 collagen type XVI alpha 1 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL16A1 mRNA PMID:38403181 13906139 CEP55 centrosomal protein 55 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CEP55 mRNA PMID:35307453 13906171 TM7SF2 transmembrane 7 superfamily member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TM7SF2 mRNA PMID:35307453 13906185 IFI6 interferon alpha inducible protein 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFI6 mRNA PMID:35307453 13906359 ZMAT2 zinc finger matrin-type 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZMAT2 mRNA PMID:35307453 13906471 RBP4 retinol binding protein 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RBP4 mRNA PMID:35307453 13906471 RBP4 retinol binding protein 4 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of RBP4 mRNA PMID:34389318 13906471 RBP4 retinol binding protein 4 gene CHEBI:17026 progesterone affects expression EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone affects the expression of RBP4 protein PMID:11833939 13906471 RBP4 retinol binding protein 4 gene CHEBI:27881 resveratrol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased expression of RBP4 protein PMID:21575630 13906471 RBP4 retinol binding protein 4 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of RBP4 protein] PMID:21739664 13906680 ATRNL1 attractin like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATRNL1 mRNA PMID:35307453 13906810 STX8 syntaxin 8 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of STX8 mRNA] PMID:21852083 13907018 WDR93 WD repeat domain 93 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WDR93 mRNA PMID:35307453 13907055 ANKRD65 ankyrin repeat domain 65 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ANKRD65 mRNA PMID:35307453 13907084 LRRFIP2 LRR binding FLII interacting protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LRRFIP2 mRNA PMID:35307453 13907175 PRSS55 serine protease 55 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRSS55 mRNA PMID:35307453 13907282 SLC15A3 solute carrier family 15 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC15A3 mRNA PMID:35307453 13907302 CXCR3 C-X-C motif chemokine receptor 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CXCR3 mRNA PMID:35307453 13907326 LOC110256677 zinc finger protein 280A-like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF280B mRNA PMID:35307453 13907397 NAF1 nuclear assembly factor 1 ribonucleoprotein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NAF1 mRNA PMID:35307453 13907768 JHY junctional cadherin complex regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of JHY mRNA PMID:35307453 13907927 ENOSF1 enolase superfamily member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENOSF1 mRNA PMID:35307453 13907976 YAE1 YAE1 maturation factor of ABCE1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of YAE1 mRNA PMID:35307453 13908045 PTBP1 polypyrimidine tract binding protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PTBP1 mRNA PMID:35307453 13908104 ZBTB24 zinc finger and BTB domain containing 24 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZBTB24 mRNA PMID:35307453 13908125 BCL2L14 BCL2 like 14 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BCL2L14 mRNA PMID:35307453 13908150 RASSF2 Ras association domain family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RASSF2 mRNA PMID:35307453 13908316 TNNT1 troponin T1, slow skeletal type gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TNNT1 mRNA PMID:35307453 13908416 TCF12 transcription factor 12 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TCF12 mRNA PMID:35307453 13908478 OTUD4 OTU deubiquitinase 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of OTUD4 mRNA PMID:35307453 13908559 CBLL1 Cbl proto-oncogene like 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CBLL1 mRNA PMID:35307453 13908745 SLC16A9 solute carrier family 16 member 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC16A9 mRNA PMID:35307453 13908832 CDHR4 cadherin related family member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDHR4 mRNA PMID:35307453 13909016 FAM187A family with sequence similarity 187 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM187A mRNA PMID:35307453 13909092 PDCD2L programmed cell death 2 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDCD2L mRNA PMID:35307453 13909112 TTC21A tetratricopeptide repeat domain 21A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TTC21A mRNA PMID:35307453 13909189 C6H1orf50 chromosome 6 C1orf50 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C6H1ORF50 mRNA PMID:35307453 13909234 FBLN2 fibulin 2 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of FBLN2 mRNA PMID:28069986 13909291 FASN fatty acid synthase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FASN mRNA PMID:35307453 13909291 FASN fatty acid synthase gene CHEBI:17234 glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of FASN mRNA PMID:25827716 13909291 FASN fatty acid synthase gene CHEBI:17234 glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] PMID:25827716 13909291 FASN fatty acid synthase gene CHEBI:17634 D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of FASN mRNA PMID:25827716 13909291 FASN fatty acid synthase gene CHEBI:17634 D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] PMID:25827716 13909291 FASN fatty acid synthase gene CHEBI:42758 aldehydo-D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of FASN mRNA PMID:25827716 13909291 FASN fatty acid synthase gene CHEBI:42758 aldehydo-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] PMID:25827716 13909291 FASN fatty acid synthase gene CHEBI:64243 monosodium L-glutamate increases expression EXP E RGD:6480464 20200317 CTD MESH:D012970 Sodium Glutamate results in increased expression of FASN mRNA PMID:31360149 13909291 FASN fatty acid synthase gene CHEBI:64243 monosodium L-glutamate multiple interactions EXP E RGD:6480464 20200317 CTD MESH:D012970 Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA] PMID:31360149 13909344 NSUN5 NOP2/Sun RNA methyltransferase 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NSUN5 mRNA; deoxynivalenol results in increased expression of NSUN5 protein PMID:35307453|PMID:38403181 13909377 DCAF15 DDB1 and CUL4 associated factor 15 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DCAF15 mRNA PMID:35307453 13909494 CCDC28A coiled-coil domain containing 28A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC28A mRNA PMID:35307453 13909504 ABLIM2 actin binding LIM protein family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABLIM2 mRNA PMID:35307453 13909504 ABLIM2 actin binding LIM protein family member 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of ABLIM2 mRNA PMID:34933075 13909593 PDP1 pyruvate dehydrogenase phosphatase catalytic subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDP1 mRNA PMID:35307453 13909626 ZNF213 zinc finger protein 213 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF213 mRNA PMID:35307453 13909639 SPEGNB SPEG neighbor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPEGNB mRNA PMID:35307453 13909710 NDRG2 NDRG family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NDRG2 mRNA PMID:35307453 13909768 RFX5 regulatory factor X5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RFX5 mRNA PMID:35307453 13909816 DDA1 DET1 and DDB1 associated 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDA1 mRNA PMID:35307453 13910089 EGFL7 EGF like domain multiple 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EGFL7 mRNA PMID:35307453 13910121 CD14 CD14 molecule gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CD14 mRNA PMID:35307453 13910121 CD14 CD14 molecule gene CHEBI:77732 cadmium nitrate affects expression EXP E RGD:6480464 20191114 CTD MESH:C035196 cadmium nitrate affects the expression of CD14 mRNA PMID:29421334 13910128 SYT12 synaptotagmin 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SYT12 mRNA PMID:35307453 13910150 FUS FUS RNA binding protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FUS mRNA PMID:35307453 13910204 SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SMARCA2 mRNA PMID:35307453 13910310 ECT2 epithelial cell transforming 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of ECT2 mRNA] PMID:21852083 13910339 EDNRA endothelin receptor type A gene CHEBI:135949 ambrisentan decreases expression EXP E RGD:6480464 20191114 CTD MESH:C467894 ambrisentan results in decreased expression of EDNRA mRNA PMID:16364719 13910359 SYT2 synaptotagmin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SYT2 mRNA PMID:35307453 13910410 KRT5 keratin 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KRT5 mRNA PMID:35307453 13910488 FAT4 FAT atypical cadherin 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAT4 mRNA PMID:35307453 13910533 CYP46A1 cytochrome P450 family 46 subfamily A member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP46A1 mRNA PMID:35307453 13910591 ABCF3 ATP binding cassette subfamily F member 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ABCF3 mRNA PMID:35307453 13910671 IL18BP interleukin 18 binding protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IL18BP mRNA PMID:35307453 13911021 SHARPIN SHANK associated RH domain interactor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SHARPIN mRNA PMID:35307453 13911119 PRPF6 pre-mRNA processing factor 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PRPF6 mRNA PMID:35307453 13911160 TGM1 transglutaminase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TGM1 mRNA PMID:35307453 13911413 NPM2 nucleophosmin/nucleoplasmin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NPM2 mRNA PMID:35307453 13911481 MRPS27 mitochondrial ribosomal protein S27 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS27 mRNA PMID:35307453 13911559 MRPS28 mitochondrial ribosomal protein S28 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS28 mRNA PMID:35307453 13911665 APOBR apolipoprotein B receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of APOBR mRNA PMID:35307453 13911673 RHOG ras homolog family member G gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RHOG mRNA PMID:35307453 13911727 OAZ3 ornithine decarboxylase antizyme 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of OAZ3 mRNA PMID:35307453 13911936 MATK megakaryocyte-associated tyrosine kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MATK mRNA PMID:35307453 13912113 YPEL2 yippee like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of YPEL2 mRNA PMID:35307453 13912134 PA2G4 proliferation-associated 2G4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PA2G4 mRNA PMID:35307453 13912305 EYA3 EYA transcriptional coactivator and phosphatase 3 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of EYA3 mRNA PMID:21852083 13912377 MPDU1 mannose-P-dolichol utilization defect 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MPDU1 mRNA PMID:35307453 13912444 BAD BCL2 associated agonist of cell death gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of BAD mRNA; deoxynivalenol results in decreased expression of BAD protein PMID:38403181 13912455 PPP1R18 protein phosphatase 1 regulatory subunit 18 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R18 mRNA PMID:35307453 13912502 FBXO28 F-box protein 28 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FBXO28 mRNA PMID:35307453 13912554 STARD4 StAR related lipid transfer domain containing 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STARD4 mRNA PMID:35307453 13912569 DNAL4 dynein axonemal light chain 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAL4 mRNA PMID:35307453 13912584 SERTM2 serine rich and transmembrane domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SERTM2 mRNA PMID:35307453 13912712 AXIN2 axin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of AXIN2 protein PMID:30690062 13912767 NHERF4 NHERF family PDZ scaffold protein 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230207 CTD MESH:C007262 deoxynivalenol results in decreased expression of NHERF4 mRNA PMID:35307453 13912798 IFI44L interferon induced protein 44 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFI44L mRNA PMID:35307453 13912989 FIP1L1 factor interacting with PAPOLA and CPSF1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FIP1L1 mRNA PMID:35307453 13913077 LOC110255237 cytochrome P450 4F6-like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP4F8 mRNA PMID:35307453 13913110 MT1A metallothionein 1A gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20200121 CTD MESH:D002104 Cadmium results in increased expression of MT1A protein PMID:12915104 13913110 MT1A metallothionein 1A gene CHEBI:35176 zinc sulfate increases expression EXP E RGD:6480464 20200121 CTD MESH:D019287 Zinc Sulfate results in increased expression of MT1A mRNA PMID:25895165 13913683 RDH10 retinol dehydrogenase 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RDH10 mRNA PMID:35307453 13913715 HSBP1L1 heat shock factor binding protein 1 like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HSBP1L1 mRNA PMID:35307453 13913859 PKP2 plakophilin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PKP2 mRNA PMID:35307453 13913912 DCN decorin gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of DCN mRNA] PMID:21852083 13914023 RIOK1 RIO kinase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RIOK1 mRNA; deoxynivalenol results in increased expression of RIOK1 protein PMID:35307453|PMID:38403181 13914107 TRIM16 tripartite motif containing 16 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRIM16 mRNA PMID:35307453 13914117 PGAP2 post-GPI attachment to proteins 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PGAP2 mRNA PMID:35307453 13914229 VPS37C VPS37C subunit of ESCRT-I gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VPS37C mRNA PMID:35307453 13914293 KDM1B lysine demethylase 1B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of KDM1B protein PMID:37257635 13914323 CSPG4 chondroitin sulfate proteoglycan 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CSPG4 mRNA PMID:35307453 13914469 MRPL48 mitochondrial ribosomal protein L48 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL48 mRNA PMID:35307453 13914521 EDC3 enhancer of mRNA decapping 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EDC3 mRNA PMID:35307453 13914542 SLC26A5 solute carrier family 26 member 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC26A5 mRNA PMID:35307453 13914568 SLC35F1 solute carrier family 35 member F1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC35F1 mRNA PMID:35307453 13914755 XDH xanthine dehydrogenase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of XDH mRNA PMID:35307453 13914755 XDH xanthine dehydrogenase gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Hydrogen Peroxide PMID:21984542 13914755 XDH xanthine dehydrogenase gene CHEBI:17245 carbon monoxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002248 [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide; CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] PMID:21984542 13914755 XDH xanthine dehydrogenase gene CHEBI:17368 hypoxanthine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019271 [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide; [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Hydrogen Peroxide; [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Superoxides; CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; CAT protein results in decreased activity of [Hypoxanthine co-treated with XDH protein]; tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol results in decreased activity of [Hypoxanthine co-treated with XDH protein] PMID:21984542 13914755 XDH xanthine dehydrogenase gene CHEBI:180664 4-hydroxy-TEMPO multiple interactions EXP E RGD:6480464 20211109 CTD MESH:C001803 tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol results in decreased activity of [Hypoxanthine co-treated with XDH protein] PMID:21984542 13914755 XDH xanthine dehydrogenase gene CHEBI:18421 superoxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013481 [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Superoxides PMID:21984542 13914844 C7 complement C7 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of C7 mRNA PMID:34389318 13914844 C7 complement C7 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of C7 mRNA PMID:18988085 13914872 GABARAPL1 GABA type A receptor associated protein like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GABARAPL1 mRNA PMID:35307453 13914872 GABARAPL1 GABA type A receptor associated protein like 1 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of GABARAPL1 mRNA PMID:35839969 13914915 FGR FGR proto-oncogene, Src family tyrosine kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FGR mRNA PMID:35307453 13915052 STXBP2 syntaxin binding protein 2 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of STXBP2 mRNA PMID:28069986 13915103 YBEY ybeY metalloendoribonuclease gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of YBEY mRNA PMID:35307453 13915225 CCNG1 cyclin G1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCNG1 mRNA PMID:35307453 13915272 FHAD1 forkhead associated phosphopeptide binding domain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FHAD1 mRNA PMID:35307453 13915338 EDN1 endothelin 1 gene CHEBI:135949 ambrisentan decreases expression EXP E RGD:6480464 20191114 CTD MESH:C467894 ambrisentan results in decreased expression of EDN1 mRNA; ambrisentan results in decreased expression of EDN1 protein PMID:16364719 13915338 EDN1 endothelin 1 gene CHEBI:15551 prostaglandin E2 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015232 [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid co-treated with EDN1 protein] results in decreased chemical synthesis of Dinoprostone PMID:16325014 13915338 EDN1 endothelin 1 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of EDN1 mRNA PMID:37706587 13915338 EDN1 endothelin 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA] PMID:37706587 13915338 EDN1 endothelin 1 gene CHEBI:16480 nitric oxide increases abundance EXP E RGD:6480464 20191114 CTD MESH:D009569 EDN1 protein results in increased abundance of Nitric Oxide PMID:12672649 13915338 EDN1 endothelin 1 gene CHEBI:16480 nitric oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009569 Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein] PMID:17105827 13915338 EDN1 endothelin 1 gene CHEBI:27958 cocaine increases expression EXP E RGD:6480464 20191114 CTD MESH:D003042 Cocaine results in increased expression of EDN1 protein PMID:9714087 13915338 EDN1 endothelin 1 gene CHEBI:27958 cocaine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003042 1,3-ditolylguanidine inhibits the reaction [Cocaine results in increased expression of EDN1 protein]; Haloperidol inhibits the reaction [Cocaine results in increased expression of EDN1 protein] PMID:9714087 13915338 EDN1 endothelin 1 gene CHEBI:28158 6-oxoprostaglandin F1alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015121 [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid co-treated with EDN1 protein] results in decreased chemical synthesis of 6-Ketoprostaglandin F1 alpha PMID:16325014 13915338 EDN1 endothelin 1 gene CHEBI:29310 dichlorine increases expression EXP E RGD:6480464 20191114 CTD MESH:D002713 Chlorine results in increased expression of EDN1 protein PMID:16625121 13915338 EDN1 endothelin 1 gene CHEBI:3441 carvedilol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased expression of EDN1 protein PMID:18840580 13915338 EDN1 endothelin 1 gene CHEBI:3441 carvedilol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C043211 Glyburide inhibits the reaction [Carvedilol results in decreased expression of EDN1 protein] PMID:18840580 13915338 EDN1 endothelin 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of EDN1 protein PMID:17105827 13915338 EDN1 endothelin 1 gene CHEBI:3750 clofibrate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein]; Clofibrate inhibits the reaction [KNG1 protein modified form results in increased expression of EDN1 protein]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein]; Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein] PMID:17105827 13915338 EDN1 endothelin 1 gene CHEBI:37537 phorbol 13-acetate 12-myristate increases expression EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein PMID:17105827 13915338 EDN1 endothelin 1 gene CHEBI:37537 phorbol 13-acetate 12-myristate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013755 Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein] PMID:17105827 13915338 EDN1 endothelin 1 gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA] PMID:37706587 13915338 EDN1 endothelin 1 gene CHEBI:4031 cyclosporin A increases secretion EXP E RGD:6480464 20191114 CTD MESH:D016572 Cyclosporine results in increased secretion of EDN1 protein PMID:16391421 13915338 EDN1 endothelin 1 gene CHEBI:5441 glyburide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005905 Glyburide inhibits the reaction [Carvedilol results in decreased expression of EDN1 protein] PMID:18840580 13915338 EDN1 endothelin 1 gene CHEBI:5613 haloperidol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006220 Haloperidol inhibits the reaction [Cocaine results in increased expression of EDN1 protein] PMID:9714087 13915435 S100A1 S100 calcium binding protein A1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100A1 mRNA PMID:35307453 13915610 AUH AU RNA binding methylglutaconyl-CoA hydratase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AUH mRNA PMID:35307453 13915759 SLC25A45 solute carrier family 25 member 45 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC25A45 mRNA PMID:35307453 13915790 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HSD11B1 mRNA PMID:35307453 13915884 FOXD4 forkhead box D4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FOXD4 mRNA PMID:35307453 13915983 CAPN10 calpain 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CAPN10 mRNA PMID:35307453 13916022 GPER1 G protein-coupled estrogen receptor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPER1 mRNA PMID:35307453 13916022 GPER1 G protein-coupled estrogen receptor 1 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006780 [bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein PMID:31266599 13916022 GPER1 G protein-coupled estrogen receptor 1 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C020806 tetrabromobisphenol A results in decreased expression of GPER1 protein PMID:31266599 13916022 GPER1 G protein-coupled estrogen receptor 1 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C020806 [tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein PMID:31266599 13916022 GPER1 G protein-coupled estrogen receptor 1 gene CHEBI:35004 Tetrachlorobisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C041181 tetrachlorodian results in decreased expression of GPER1 protein PMID:31266599 13916022 GPER1 G protein-coupled estrogen receptor 1 gene CHEBI:35004 Tetrachlorobisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C041181 tetrachlorodian inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of GPER1 protein] PMID:31266599 13916047 HFE homeostatic iron regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HFE mRNA PMID:35307453 13916068 PTPRZ1 protein tyrosine phosphatase receptor type Z1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PTPRZ1 mRNA PMID:35307453 13916117 EGF epidermal growth factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EGF mRNA PMID:35307453 13916290 CSTB cystatin B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CSTB mRNA PMID:35307453 13916489 TPK1 thiamin pyrophosphokinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TPK1 mRNA PMID:35307453 13916690 GDF9 growth differentiation factor 9 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of GDF9 mRNA PMID:25455459 13916694 CTNNBIP1 catenin beta interacting protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTNNBIP1 mRNA PMID:35307453 13916721 CFAP52 cilia and flagella associated protein 52 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP52 mRNA PMID:35307453 13916750 PRSS23 serine protease 23 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRSS23 mRNA PMID:35307453 13916819 GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GALNT15 mRNA PMID:35307453 13916843 CYB561 cytochrome b561 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYB561 mRNA PMID:35307453 13916843 CYB561 cytochrome b561 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of CYB561 mRNA PMID:21852083 13916938 GPD2 glycerol-3-phosphate dehydrogenase 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of GPD2 mRNA PMID:21852083 13917103 OGFOD2 2-oxoglutarate and iron dependent oxygenase domain containing 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of OGFOD2 mRNA PMID:35307453 13917174 APEH acylaminoacyl-peptide hydrolase gene CHEBI:17941 diisopropyl fluorophosphate decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007531 Isoflurophate results in decreased activity of APEH protein PMID:10953051 13917174 APEH acylaminoacyl-peptide hydrolase gene CHEBI:34632 chlorpyrifos-methyl decreases activity EXP E RGD:6480464 20191114 CTD MESH:C007031 chlorpyrifos-methyl results in decreased activity of APEH protein PMID:10953051 13917174 APEH acylaminoacyl-peptide hydrolase gene CHEBI:34690 dichlorvos decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004006 Dichlorvos results in decreased activity of APEH protein PMID:10953051 13917312 SNAP47 synaptosome associated protein 47 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SNAP47 mRNA PMID:35307453 13917448 ATP6V0D2 ATPase H+ transporting V0 subunit d2 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of ATP6V0D2 mRNA PMID:28069986 13917471 NARS1 asparaginyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NARS1 mRNA PMID:35307453 13917513 LARP1B La ribonucleoprotein 1B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LARP1B mRNA PMID:35307453 13917706 FAM234A family with sequence similarity 234 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM234A mRNA PMID:35307453 13917774 TNFSF4 TNF superfamily member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TNFSF4 mRNA PMID:35307453 13917869 ACE2 angiotensin converting enzyme 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of ACE2 mRNA PMID:34933075 13917926 PFDN6 prefoldin subunit 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PFDN6 mRNA PMID:35307453 13917973 LEF1 lymphoid enhancer binding factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LEF1 mRNA PMID:35307453 13918031 USHBP1 USH1 protein network component harmonin binding protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of USHBP1 mRNA PMID:35307453 13918047 ZHX3 zinc fingers and homeoboxes 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZHX3 mRNA PMID:35307453 13918183 MADCAM1 mucosal vascular addressin cell adhesion molecule 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MADCAM1 mRNA PMID:35307453 13918241 WT1 WT1 transcription factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WT1 mRNA PMID:35307453 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D005978 Glutathione inhibits the reaction [Paraquat results in increased expression of AOC1 protein] PMID:36615853 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:17148 putrescine increases degradation EXP E RGD:6480464 20191114 CTD MESH:D011700 AOC1 protein results in increased degradation of Putrescine PMID:8144586 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in increased expression of AOC1 protein PMID:36615853 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D010269 Glutathione inhibits the reaction [Paraquat results in increased expression of AOC1 protein] PMID:36615853 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:34919 Phenylamil affects binding EXP E RGD:6480464 20191114 CTD MESH:C047088 phenylamil binds to AOC1 protein PMID:8144586 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:35696 cobalt dichloride affects binding EXP E RGD:6480464 20191114 CTD MESH:C018021 cobaltous chloride binds to AOC1 protein PMID:16842785 13918368 AOC1 amine oxidase copper containing 1 gene CHEBI:49553 copper(II) chloride increases activity EXP E RGD:6480464 20191114 CTD MESH:C029892 cupric chloride results in increased activity of AOC1 protein PMID:16842785 13918601 NR1H4 nuclear receptor subfamily 1 group H member 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NR1H4 mRNA PMID:35307453 13918649 SQSTM1 sequestosome 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20200714 CTD MESH:C007262 deoxynivalenol results in increased expression of SQSTM1 mRNA; deoxynivalenol results in increased expression of SQSTM1 protein PMID:32302720|PMID:38403181 13918649 SQSTM1 sequestosome 1 gene CHEBI:27744 glyphosate decreases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in decreased expression of SQSTM1 protein PMID:35388968 13918649 SQSTM1 sequestosome 1 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of SQSTM1 protein] PMID:35388968 13918649 SQSTM1 sequestosome 1 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20230307 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of SQSTM1 protein] PMID:35388968 13918649 SQSTM1 sequestosome 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]] PMID:34811946 13918649 SQSTM1 sequestosome 1 gene CHEBI:35176 zinc sulfate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019287 Zinc Sulfate results in decreased expression of SQSTM1 protein PMID:28803810 13918649 SQSTM1 sequestosome 1 gene CHEBI:35176 zinc sulfate increases expression EXP E RGD:6480464 20191114 CTD MESH:D019287 Zinc Sulfate results in increased expression of SQSTM1 mRNA PMID:28803810 13918649 SQSTM1 sequestosome 1 gene CHEBI:35176 zinc sulfate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019287 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein] PMID:28803810 13918649 SQSTM1 sequestosome 1 gene CHEBI:3638 chloroquine increases expression EXP E RGD:6480464 20191114 CTD MESH:D002738 Chloroquine results in increased expression of SQSTM1 protein PMID:30287338 13918649 SQSTM1 sequestosome 1 gene CHEBI:3638 chloroquine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002738 Chloroquine inhibits the reaction [ochratoxin A results in decreased expression of SQSTM1 protein] PMID:30287338 13918649 SQSTM1 sequestosome 1 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20240903 CTD MESH:C056933 fumonisin B1 results in increased expression of SQSTM1 mRNA; fumonisin B1 results in increased expression of SQSTM1 protein PMID:38705344 13918649 SQSTM1 sequestosome 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C056933 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [fumonisin B1 results in decreased expression of SQSTM1 mRNA]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [fumonisin B1 results in decreased expression of SQSTM1 protein]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [fumonisin B1 results in increased lipidation of and results in increased localization of SQSTM1 protein] PMID:38705344 13918649 SQSTM1 sequestosome 1 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025946 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein] PMID:28803810|PMID:34811946 13918649 SQSTM1 sequestosome 1 gene CHEBI:50842 norflurazon increases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in increased phosphorylation of SQSTM1 protein PMID:38432436 13918649 SQSTM1 sequestosome 1 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of SQSTM1 protein PMID:30287338 13918649 SQSTM1 sequestosome 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 Chloroquine inhibits the reaction [ochratoxin A results in decreased expression of SQSTM1 protein] PMID:30287338 13918649 SQSTM1 sequestosome 1 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]] PMID:34811946 13918796 PRR5L proline rich 5 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRR5L mRNA PMID:35307453 13918853 PLEKHB1 pleckstrin homology domain containing B1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLEKHB1 mRNA PMID:35307453 13918908 SLC27A3 solute carrier family 27 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC27A3 mRNA PMID:35307453 13919026 PRKN parkin RBR E3 ubiquitin protein ligase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRKN mRNA PMID:35307453 13919026 PRKN parkin RBR E3 ubiquitin protein ligase gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20240903 CTD MESH:C056933 fumonisin B1 results in increased expression of PRKN mRNA; fumonisin B1 results in increased expression of PRKN protein PMID:38705344 13919026 PRKN parkin RBR E3 ubiquitin protein ligase gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C056933 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [fumonisin B1 results in increased expression of PRKN mRNA]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [fumonisin B1 results in increased expression of PRKN protein] PMID:38705344 13919563 GADD45GIP1 GADD45G interacting protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GADD45GIP1 mRNA PMID:35307453 13919583 ATP5MC2 ATP synthase membrane subunit c locus 2 gene CHEBI:50842 norflurazon decreases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased expression of ATP5MC2 mRNA PMID:38432436 13919614 STMN1 stathmin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STMN1 mRNA PMID:35307453 13919641 JPT2 Jupiter microtubule associated homolog 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of JPT2 mRNA PMID:35307453 13919687 LOC100512181 BTB/POZ domain-containing protein KCTD14 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KCTD14 mRNA PMID:35307453 13919688 TBL3 transducin beta like 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TBL3 mRNA PMID:35307453 13919730 ARPC2 actin related protein 2/3 complex subunit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARPC2 mRNA PMID:35307453 13919745 ITPKB inositol-trisphosphate 3-kinase B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITPKB mRNA PMID:35307453 13919745 ITPKB inositol-trisphosphate 3-kinase B gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of ITPKB mRNA PMID:34389318 13919820 RAB17 RAB17, member RAS oncogene family gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAB17 mRNA PMID:35307453 13919920 IGFBP6 insulin like growth factor binding protein 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IGFBP6 mRNA PMID:35307453 13919958 DOCK7 dedicator of cytokinesis 7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DOCK7 mRNA PMID:35307453 13920049 N6AMT1 N-6 adenine-specific DNA methyltransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of N6AMT1 mRNA PMID:35307453 13920321 PSMD14 proteasome 26S subunit, non-ATPase 14 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMD14 mRNA PMID:35307453 13920321 PSMD14 proteasome 26S subunit, non-ATPase 14 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of PSMD14 mRNA PMID:35839969 13920360 TREM2 triggering receptor expressed on myeloid cells 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of TREM2 mRNA PMID:34933075 13920427 ADRA1D adrenoceptor alpha 1D gene CHEBI:8093 phenylephrine increases activity EXP E RGD:6480464 20191114 CTD MESH:D010656 Phenylephrine results in increased activity of ADRA1D protein PMID:19376108 13920609 YRDC yrdC N6-threonylcarbamoyltransferase domain containing gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of YRDC mRNA PMID:35307453 13920654 GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GALNT2 mRNA PMID:35307453 13920729 NSUN7 NOP2/Sun RNA methyltransferase family member 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NSUN7 mRNA PMID:35307453 13920774 MDH1 malate dehydrogenase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MDH1 mRNA PMID:35307453 13920849 RPGR retinitis pigmentosa GTPase regulator gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of RPGR mRNA PMID:35307453 13920906 CNTROB centrobin, centriole duplication and spindle assembly protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CNTROB mRNA PMID:35307453 13921181 KCNK3 potassium two pore domain channel subfamily K member 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of KCNK3 mRNA PMID:34933075 13921225 VTCN1 V-set domain containing T cell activation inhibitor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VTCN1 mRNA PMID:35307453 13921225 VTCN1 V-set domain containing T cell activation inhibitor 1 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of VTCN1 mRNA PMID:34933075 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FOS mRNA PMID:35307453 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20221206 CTD MESH:C007262 deoxynivalenol results in increased expression of FOS mRNA PMID:35314294 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:135697 sarpogrelate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C064294 sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein] PMID:11426759 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:136004 linsidomine increases expression EXP E RGD:6480464 20191114 CTD MESH:C002385 linsidomine results in increased expression of FOS mRNA PMID:18086661 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of FOS mRNA PMID:34389318 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of FOS mRNA PMID:18086661|PMID:37706587 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS mRNA] PMID:37706587 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of FOS mRNA PMID:18988085|PMID:27617619 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:27666 actinomycin D multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003609 Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of FOS mRNA] PMID:9463523 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:28790 serotonin increases expression EXP E RGD:6480464 20191114 CTD MESH:D012701 Serotonin results in increased expression of FOS mRNA; Serotonin results in increased expression of FOS protein PMID:11426759 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:28790 serotonin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012701 sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein] PMID:11426759 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] PMID:18086661 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of FOS mRNA PMID:21391292 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:29310 dichlorine increases expression EXP E RGD:6480464 20191114 CTD MESH:D002713 Chlorine results in increased expression of FOS mRNA PMID:22533443 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:31823 mercury dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased expression of FOS mRNA; Mercuric Chloride results in increased expression of FOS protein PMID:9463523 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:31823 mercury dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008627 Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of FOS mRNA] PMID:9463523 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased expression of FOS mRNA PMID:18086661|PMID:7564105 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] PMID:18086661|PMID:7564105 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS mRNA] PMID:37706587 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:43385 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] PMID:7564105 13921310 FOS Fos proto-oncogene, AP-1 transcription factor subunit gene CHEBI:83438 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] PMID:7564105 13921361 CDH17 cadherin 17 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDH17 mRNA PMID:35307453 13921361 CDH17 cadherin 17 gene CHEBI:10106 zearalenone affects expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone affects the expression of CDH17 mRNA PMID:34933075 13921415 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCMTD1 mRNA PMID:35307453 13921442 MEGF10 multiple EGF like domains 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MEGF10 mRNA PMID:35307453 13921538 CLDN3 claudin 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191224 CTD MESH:C007262 deoxynivalenol analog results in decreased expression of CLDN3 protein; deoxynivalenol results in decreased expression of CLDN3 mRNA; deoxynivalenol results in decreased expression of CLDN3 protein PMID:19289138|PMID:22859312|PMID:35307453|PMID:36596350 13921538 CLDN3 claudin 3 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C007262 Pioglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]; PPARG protein affects the reaction [Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]; T 0070907 inhibits the reaction [Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; T 0070907 inhibits the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein] PMID:36596350 13921538 CLDN3 claudin 3 gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of CLDN3 protein PMID:36754226 13921538 CLDN3 claudin 3 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D001564 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of CLDN3 protein] PMID:36754226 13921538 CLDN3 claudin 3 gene CHEBI:33709 amino acid multiple interactions EXP E RGD:6480464 20191224 CTD MESH:D000596 Amino Acids inhibits the reaction [Diquat results in decreased expression of CLDN3 protein] PMID:26338884 13921538 CLDN3 claudin 3 gene CHEBI:41500 4-phenylbutyric acid multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C075773 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of CLDN3 protein] PMID:36754226 13921538 CLDN3 claudin 3 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20191224 CTD MESH:D004178 Diquat results in decreased expression of CLDN3 protein PMID:26338884 13921538 CLDN3 claudin 3 gene CHEBI:64163 diquat multiple interactions EXP E RGD:6480464 20191224 CTD MESH:D004178 Amino Acids inhibits the reaction [Diquat results in decreased expression of CLDN3 protein] PMID:26338884 13921538 CLDN3 claudin 3 gene CHEBI:8228 pioglitazone multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C060836 Pioglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein] PMID:36596350 13921538 CLDN3 claudin 3 gene CHEBI:9753 troglitazone increases expression EXP E RGD:6480464 20230502 CTD MESH:C057693 Troglitazone results in increased expression of CLDN3 protein PMID:36596350 13921538 CLDN3 claudin 3 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C057693 PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; T 0070907 inhibits the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein] PMID:36596350 13921649 IER5L immediate early response 5 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IER5L mRNA PMID:35307453 13921673 LAMA1 laminin subunit alpha 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LAMA1 mRNA PMID:35307453 13921745 PDGFB platelet derived growth factor subunit B gene CHEBI:16469 17beta-estradiol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol affects the secretion of [PDGFB protein binds to PDGFB protein] PMID:15653758 13921745 PDGFB platelet derived growth factor subunit B gene CHEBI:8772 raloxifene multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride affects the secretion of [PDGFB protein binds to PDGFB protein] PMID:15653758 13921765 BAG5 BAG cochaperone 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BAG5 mRNA PMID:35307453 13921868 CA3 carbonic anhydrase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CA3 mRNA PMID:35307453 13921879 SLC16A14 solute carrier family 16 member 14 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC16A14 mRNA PMID:35307453 13921891 CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 gene CHEBI:42797 gabapentin affects binding EXP E RGD:6480464 20191114 CTD MESH:C040029 Gabapentin binds to CACNA2D1 protein PMID:11687876 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPX4 mRNA PMID:25701311|PMID:35307453 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:15891 taurine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D013654 Taurine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA] PMID:36281498 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:16796 melatonin increases expression EXP E RGD:6480464 20201103 CTD MESH:D008550 Melatonin results in increased expression of GPX4 mRNA PMID:31535366 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D005978 [Glutathione co-treated with Paraquat] results in increased expression of GPX4 mRNA PMID:36615853 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPX4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GPX4 mRNA PMID:33493553|PMID:34416349 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D000111 Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA] PMID:36281498 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:3259 CCCP multiple interactions EXP E RGD:6480464 20240903 CTD MESH:D002258 Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [Diquat results in decreased expression of GPX4 mRNA] PMID:38567716 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in increased expression of GPX4 mRNA PMID:36615853 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D010269 [Glutathione co-treated with Paraquat] results in increased expression of GPX4 mRNA PMID:36615853 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPX4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GPX4 mRNA PMID:33493553|PMID:34416349 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:48843 disodium selenite increases activity EXP E RGD:6480464 20191114 CTD MESH:D018038 Sodium Selenite results in increased activity of GPX4 protein PMID:10998458 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20240903 CTD MESH:D004178 Diquat results in decreased expression of GPX4 mRNA PMID:38567716 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:64163 diquat multiple interactions EXP E RGD:6480464 20240903 CTD MESH:D004178 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Diquat results in decreased expression of GPX4 mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [Diquat results in decreased expression of GPX4 mRNA] PMID:38567716 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of GPX4 mRNA PMID:31535366 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20230502 CTD MESH:C025589 ochratoxin A results in decreased expression of GPX4 mRNA PMID:36281498 13921981 GPX4 glutathione peroxidase 4 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C025589 Acetylcysteine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA] PMID:36281498 13922132 MED6 mediator complex subunit 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MED6 mRNA PMID:35307453 13922187 ASB4 ankyrin repeat and SOCS box containing 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASB4 mRNA PMID:35307453 13922261 SZT2 SZT2 subunit of KICSTOR complex gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SZT2 mRNA PMID:35307453 13922373 APCDD1 APC down-regulated 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of APCDD1 mRNA PMID:35307453 13922515 NXPE3 neurexophilin and PC-esterase domain family member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NXPE3 mRNA PMID:35307453 13922546 GAL3ST1 galactose-3-O-sulfotransferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GAL3ST1 mRNA PMID:35307453 13922633 P3H2 prolyl 3-hydroxylase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of P3H2 mRNA PMID:35307453 13922889 SPOUT1 SPOUT domain containing methyltransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SPOUT1 mRNA PMID:35307453 13922976 BCO1 beta-carotene oxygenase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BCO1 mRNA PMID:35307453 13923035 GNS glucosamine (N-acetyl)-6-sulfatase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GNS mRNA PMID:35307453 13923158 CTSF cathepsin F gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTSF mRNA PMID:35307453 13923228 ELN elastin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ELN mRNA PMID:35307453 13923306 ARB2A ARB2 cotranscriptional regulator A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARB2A mRNA PMID:37120089 13923306 ARB2A ARB2 cotranscriptional regulator A gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ARB2A mRNA] PMID:37120089 13923306 ARB2A ARB2 cotranscriptional regulator A gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ARB2A mRNA] PMID:37120089 13923397 GFAP glial fibrillary acidic protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GFAP mRNA PMID:35307453 13923609 ITGA8 integrin subunit alpha 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITGA8 mRNA; deoxynivalenol results in decreased expression of ITGA8 protein PMID:38403181 13923609 ITGA8 integrin subunit alpha 8 gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in decreased expression of ITGA8 mRNA PMID:22497863 13923644 PRSS16 serine protease 16 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRSS16 mRNA PMID:35307453 13923644 PRSS16 serine protease 16 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of PRSS16 mRNA] PMID:21852083 13923755 GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of GCNT3 mRNA PMID:34933075 13923809 FN1 fibronectin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of FN1 protein PMID:38403181 13923809 FN1 fibronectin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FN1 mRNA PMID:35307453 13923809 FN1 fibronectin 1 gene CHEBI:17224 4-methylumbelliferone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D006923 Hymecromone results in decreased expression of FN1 mRNA; Hymecromone results in decreased expression of FN1 protein PMID:23139787 13923809 FN1 fibronectin 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FN1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FN1 protein PMID:34416349 13923809 FN1 fibronectin 1 gene CHEBI:2814 arecoline increases expression EXP E RGD:6480464 20191114 CTD MESH:D001115 Arecoline results in increased expression of FN1 protein PMID:26908192 13923809 FN1 fibronectin 1 gene CHEBI:2814 arecoline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001115 pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of FN1 protein] PMID:26908192 13923809 FN1 fibronectin 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FN1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FN1 protein PMID:34416349 13923809 FN1 fibronectin 1 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of FN1 protein] PMID:26908192 13923908 NIT2 nitrilase family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NIT2 mRNA PMID:35307453 13923958 GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GALNT6 mRNA PMID:35307453 13923958 GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of GALNT6 mRNA PMID:34933075 13923959 C6H16orf46 chromosome 6 C16orf46 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C6H16ORF46 mRNA PMID:35307453 13924005 JUND JunD proto-oncogene, AP-1 transcription factor subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of JUND mRNA PMID:35307453 13924063 C4H8orf33 chromosome 4 C8orf33 homolog gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol affects the expression of C4H8ORF33 mRNA PMID:35307453 13924387 NCOA1 nuclear receptor coactivator 1 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of NCOA1 mRNA PMID:34389318 13924523 IL15 interleukin 15 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of IL15 mRNA PMID:37706587 13924523 IL15 interleukin 15 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of IL15 mRNA] PMID:37706587 13924523 IL15 interleukin 15 gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of IL15 mRNA] PMID:37706587 13924614 IL12B interleukin 12B gene CHEBI:3638 chloroquine multiple interactions EXP E RGD:6480464 20200331 CTD MESH:D002738 Chloroquine inhibits the reaction [SZU-101 results in increased expression of IL12B mRNA] PMID:27079946 13924656 OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of OTUB2 mRNA PMID:35307453 13924666 LCA5 lebercilin LCA5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LCA5 mRNA PMID:35307453 13924688 TTC24 tetratricopeptide repeat domain 24 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TTC24 mRNA PMID:35307453 13924988 MMP25 matrix metallopeptidase 25 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MMP25 mRNA PMID:35307453 13925002 DPP3 dipeptidyl peptidase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DPP3 mRNA PMID:35307453 13925085 HEPACAM2 HEPACAM family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HEPACAM2 mRNA PMID:35307453 13925142 HM13 histocompatibility minor 13 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HM13 mRNA PMID:35307453 13925273 FLNB filamin B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FLNB mRNA PMID:35307453 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] PMID:17656051 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]; Zearalenone promotes the reaction [FSHB protein results in increased abundance of Progesterone] PMID:17656051 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:16170 mercury(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone PMID:20390873 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:16422 androst-4-ene-3,17-dione multiple interactions EXP E RGD:6480464 20211109 CTD MESH:D000735 [FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol; bisphenol AF inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol] PMID:34019995 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:16469 17beta-estradiol increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:D004958 FSHB protein results in increased chemical synthesis of Estradiol PMID:29273543 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:16469 17beta-estradiol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004958 [FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol; [FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol; bisphenol AF inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol] PMID:17656051|PMID:29273543|PMID:34019995 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:17026 progesterone increases abundance EXP E RGD:6480464 20191114 CTD MESH:D011374 FSHB protein results in increased abundance of Progesterone PMID:17656051|PMID:23375200 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:17026 progesterone increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:D011374 FSHB protein results in increased chemical synthesis of Progesterone PMID:20965553 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:17026 progesterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011374 4,4'-bisphenol F inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; [FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone; [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone; bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; bisphenol AF inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol S inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone; Lapatinib inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; Zearalenone promotes the reaction [FSHB protein results in increased abundance of Progesterone] PMID:17656051|PMID:20390873|PMID:23375200|PMID:29544186|PMID:34019995 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:25195 mercury atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone PMID:20390873 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:27889 lead(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007854 [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone PMID:20390873 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:31767 lead diacetate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C008261 lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol] PMID:29273543 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]] PMID:29544186|PMID:34019995 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:34372 4,4'-sulfonyldiphenol multiple interactions EXP E RGD:6480464 20211109 CTD MESH:C543008 bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; bisphenol S inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone] PMID:34019995 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:34575 bisphenol F multiple interactions EXP E RGD:6480464 20211109 CTD MESH:C008745 4,4'-bisphenol F inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone] PMID:34019995 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:42567 fisetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C017875 bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]] PMID:29544186 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:49603 lapatinib decreases activity EXP E RGD:6480464 20191114 CTD MESH:C490728 Lapatinib results in decreased activity of FSHB protein PMID:23375200 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:49603 lapatinib multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C490728 Lapatinib inhibits the reaction [FSHB protein results in increased abundance of Progesterone] PMID:23375200 13925527 FSHB follicle stimulating hormone subunit beta gene CHEBI:72754 bisphenol AF multiple interactions EXP E RGD:6480464 20250114 CTD MESH:C583074 bisphenol AF inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; bisphenol AF inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone] PMID:34019995 13925534 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SUGT1 mRNA PMID:35307453 13925552 PPP4R2 protein phosphatase 4 regulatory subunit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP4R2 mRNA PMID:35307453 13925730 C2H11orf24 chromosome 2 C11orf24 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of C2H11ORF24 mRNA PMID:35307453 13925844 RALA RAS like proto-oncogene A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RALA mRNA PMID:35307453 13925899 SH3TC1 SH3 domain and tetratricopeptide repeats 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SH3TC1 mRNA PMID:35307453 13926035 BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BAIAP2L1 mRNA PMID:35307453 13926188 PMM1 phosphomannomutase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PMM1 mRNA PMID:35307453 13926238 SYT7 synaptotagmin 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SYT7 mRNA PMID:35307453 13926418 PRIM2 DNA primase subunit 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRIM2 mRNA PMID:35307453 13926575 DPRX divergent-paired related homeobox gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DPRX mRNA PMID:35307453 13926666 SNRPC small nuclear ribonucleoprotein polypeptide C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SNRPC mRNA PMID:35307453 13926728 ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADAMTS13 mRNA PMID:35307453 13926907 STK10 serine/threonine kinase 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STK10 mRNA PMID:35307453 13927045 MTARC1 mitochondrial amidoxime reducing component 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MTARC1 mRNA PMID:35307453 13927088 ANKRD55 ankyrin repeat domain 55 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ANKRD55 mRNA PMID:35307453 13927251 ABI3BP ABI family member 3 binding protein gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of ABI3BP mRNA PMID:34389318 13927395 EFL1 elongation factor like GTPase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EFL1 mRNA PMID:35307453 13927430 H2AX H2A.X variant histone gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol results in increased expression of and results in increased phosphorylation of H2AX protein PMID:38104654 13927430 H2AX H2A.X variant histone gene CHEBI:146195 3-acetyldeoxynivalenol increases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in increased expression of H2AX protein PMID:37659622 13927430 H2AX H2A.X variant histone gene CHEBI:146195 3-acetyldeoxynivalenol multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C043247 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of H2AX protein] PMID:37659622 13927430 H2AX H2A.X variant histone gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20230704 CTD MESH:D008070 Lipopolysaccharides results in increased expression of H2AX protein PMID:36549457 13927430 H2AX H2A.X variant histone gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D008070 Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of H2AX protein] PMID:36549457 13927430 H2AX H2A.X variant histone gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C059514 Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of H2AX protein] PMID:36549457 13927430 H2AX H2A.X variant histone gene CHEBI:29865 benzo[a]pyrene increases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in increased expression of H2AX protein PMID:36754226 13927430 H2AX H2A.X variant histone gene CHEBI:4027 cyclophosphamide increases expression EXP E RGD:6480464 20240109 CTD MESH:D003520 Cyclophosphamide results in increased expression of H2AX protein PMID:37980972 13927430 H2AX H2A.X variant histone gene CHEBI:4027 cyclophosphamide multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D003520 Panobinostat inhibits the reaction [Cyclophosphamide results in increased expression of H2AX protein] PMID:37980972 13927430 H2AX H2A.X variant histone gene CHEBI:50131 5-aza-2'-deoxycytidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C014347 Decitabine inhibits the reaction [ochratoxin A results in increased expression of H2AX protein] PMID:30923867 13927430 H2AX H2A.X variant histone gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased expression of H2AX protein PMID:30923867|PMID:32454083 13927430 H2AX H2A.X variant histone gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [ochratoxin A results in increased expression of H2AX protein]; Decitabine inhibits the reaction [ochratoxin A results in increased expression of H2AX protein]; STAT3 protein affects the reaction [ochratoxin A results in increased expression of H2AX protein] PMID:30923867 13927430 H2AX H2A.X variant histone gene CHEBI:85990 panobinostat multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C496932 Panobinostat inhibits the reaction [Cyclophosphamide results in increased expression of H2AX protein] PMID:37980972 13927430 H2AX H2A.X variant histone gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D020123 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of H2AX protein] PMID:37659622 13927580 UBB ubiquitin B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBB mRNA PMID:35307453 13927639 SLC46A2 solute carrier family 46 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC46A2 mRNA PMID:35307453 13927650 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAB1 mRNA PMID:34416349 13927650 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAB1 mRNA PMID:34416349 13927680 SMU1 SMU1 DNA replication regulator and spliceosomal factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMU1 mRNA PMID:35307453 13927718 BBOX1 gamma-butyrobetaine hydroxylase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BBOX1 mRNA PMID:35307453 13927856 SMTNL2 smoothelin like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SMTNL2 mRNA PMID:35307453|PMID:37257635 13927957 FARP1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FARP1 mRNA PMID:35307453 13928116 TTC17 tetratricopeptide repeat domain 17 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TTC17 mRNA PMID:35307453 13928153 SEMA6B semaphorin 6B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SEMA6B mRNA PMID:35307453 13928301 IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IDH3B mRNA PMID:35307453 13928330 RAMP1 receptor activity modifying protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAMP1 mRNA PMID:35307453 13928365 AXDND1 axonemal dynein light chain domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AXDND1 mRNA PMID:35307453 13928608 C2CD4B C2 calcium dependent domain containing 4B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of C2CD4B mRNA PMID:35307453 13928800 CHRM4 cholinergic receptor muscarinic 4 gene CHEBI:5720 himbacine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C048172 himbacine inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM4 protein] PMID:8744975 13928800 CHRM4 cholinergic receptor muscarinic 4 gene CHEBI:9757 Tropicamide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014331 Tropicamide inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM4 protein] PMID:8744975 13928806 S100A4 S100 calcium binding protein A4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100A4 mRNA PMID:35307453 13928824 MPC1 mitochondrial pyruvate carrier 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MPC1 mRNA PMID:35307453 13929008 SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SHQ1 mRNA PMID:35307453 13929027 LBP lipopolysaccharide binding protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LBP mRNA PMID:35307453 13929046 PLCH1 phospholipase C eta 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLCH1 mRNA PMID:35307453 13929150 CYP11B2 cytochrome P450 family 11 subfamily B member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CYP11B2 mRNA PMID:35307453 13929227 SLFN11 schlafen family member 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLFN11 mRNA; deoxynivalenol results in decreased expression of SLFN11 protein PMID:38403181 13929241 C5H22orf23 chromosome 5 C22orf23 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C5H22ORF23 mRNA PMID:35307453 13929274 SLC4A4 solute carrier family 4 member 4 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of SLC4A4 mRNA] PMID:21852083 13929361 MBTD1 mbt domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MBTD1 mRNA PMID:35307453 13929698 COPS5 COP9 signalosome subunit 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of COPS5 mRNA PMID:35307453 13929728 GHSR growth hormone secretagogue receptor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GHSR mRNA PMID:35307453 13929825 SLC34A2 solute carrier family 34 member 2 gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of SLC34A2 mRNA PMID:31535366 13929843 ID2 inhibitor of DNA binding 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ID2 mRNA PMID:35307453 13929843 ID2 inhibitor of DNA binding 2 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of ID2 mRNA PMID:14994279 13930017 ZNF385B zinc finger protein 385B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF385B mRNA PMID:35307453 13930129 C1RL complement C1r subcomponent like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C1RL mRNA PMID:35307453 13930235 LOXL2 lysyl oxidase like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of LOXL2 mRNA; deoxynivalenol results in decreased expression of LOXL2 protein PMID:38403181 13930294 DCLK3 doublecortin like kinase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DCLK3 mRNA PMID:35307453 13930320 MRPL42 mitochondrial ribosomal protein L42 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL42 mRNA PMID:35307453 13930334 PSMD8 proteasome 26S subunit, non-ATPase 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMD8 mRNA PMID:35307453 13930373 TMF1 TATA element modulatory factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMF1 mRNA PMID:35307453 13930398 C8H4orf19 chromosome 8 C4orf19 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C8H4ORF19 mRNA PMID:35307453 13930455 WIPI1 WD repeat domain, phosphoinositide interacting 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WIPI1 mRNA PMID:35307453 13930669 NTRK1 neurotrophic receptor tyrosine kinase 1 gene CHEBI:64310 crizotinib decreases activity EXP E RGD:6480464 20191114 CTD MESH:C551994 Crizotinib results in decreased activity of NTRK1 protein PMID:21812414 13930697 AVP vasopressin gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of AVP mRNA PMID:34389318 13930729 REEP5 receptor accessory protein 5 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of REEP5 mRNA PMID:21852083 13930830 ZNF593 zinc finger protein 593 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF593 mRNA PMID:35307453 13930940 MYG1 MYG1 exonuclease gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20250128 CTD MESH:C025589 ochratoxin A results in decreased expression of PFDN5 mRNA PMID:14994279 13930994 CCDC88C coiled-coil domain containing 88C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC88C mRNA PMID:35307453 13931032 JUP junction plakoglobin gene CHEBI:3441 carvedilol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased expression of JUP mRNA PMID:16824628 13931032 JUP junction plakoglobin gene CHEBI:3441 carvedilol increases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in increased expression of JUP protein PMID:16824628 13931252 LAPTM4B lysosomal protein transmembrane 4 beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LAPTM4B mRNA PMID:35307453 13931305 PPIL6 peptidylprolyl isomerase like 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PPIL6 mRNA PMID:35307453 13931401 SCPEP1 serine carboxypeptidase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCPEP1 mRNA PMID:35307453 13931401 SCPEP1 serine carboxypeptidase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of SCPEP1 mRNA PMID:21852083 13931460 DNAL1 dynein axonemal light chain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAL1 mRNA PMID:35307453 13931505 THRSP thyroid hormone responsive gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of THRSP mRNA PMID:35307453 13931656 SLC26A3 solute carrier family 26 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC26A3 mRNA PMID:35307453 13931769 ATP4A ATPase H+/K+ transporting subunit alpha gene CHEBI:30751 formic acid decreases expression EXP E RGD:6480464 20191114 CTD MESH:C030544 formic acid results in decreased expression of ATP4A mRNA PMID:16614409 13931769 ATP4A ATPase H+/K+ transporting subunit alpha gene CHEBI:77543 ebselen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C042986 ebselen results in decreased activity of [ATP4A protein binds to ATP4B protein] PMID:7590103 13931888 RPL7L1 ribosomal protein L7 like 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RPL7L1 mRNA PMID:35307453 13931933 WDR19 WD repeat domain 19 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WDR19 mRNA; deoxynivalenol results in decreased expression of WDR19 protein PMID:35307453|PMID:38403181 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCL20 mRNA PMID:35307453 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of CCL20 mRNA PMID:23326479|PMID:35314294 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007262 [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA] PMID:30708112 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of CCL20 mRNA PMID:25455459 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of CCL20 mRNA PMID:37706587 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL20 mRNA] PMID:37706587 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008070 [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA] PMID:30708112 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL20 mRNA] PMID:37706587 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20191114 CTD MESH:C056933 fumonisin B1 results in increased expression of CCL20 mRNA PMID:30708112 13932142 CCL20 C-C motif chemokine ligand 20 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C056933 fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA] PMID:30708112 13932207 IGSF3 immunoglobulin superfamily member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IGSF3 mRNA PMID:35307453 13932207 IGSF3 immunoglobulin superfamily member 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of IGSF3 mRNA PMID:34933075 13932224 TYR tyrosinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TYR mRNA PMID:35307453 13932283 RNASET2 ribonuclease T2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RNASET2 mRNA PMID:35307453 13932374 TJP1 tight junction protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of TJP1 mRNA; deoxynivalenol results in decreased expression of TJP1 protein PMID:20937367|PMID:35307453|PMID:35381244|PMID:37120089|PMID:37442268 13932374 TJP1 tight junction protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of TJP1 mRNA PMID:26417708 13932374 TJP1 tight junction protein 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20210309 CTD MESH:C007262 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 protein]; MAP1LC3B protein affects the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 protein]]; Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein]; Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein] PMID:32877744|PMID:35381244|PMID:37120089|PMID:37442268 13932374 TJP1 tight junction protein 1 gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of TJP1 protein PMID:37659622 13932374 TJP1 tight junction protein 1 gene CHEBI:16240 hydrogen peroxide decreases expression EXP E RGD:6480464 20240903 CTD MESH:D006861 Hydrogen Peroxide results in decreased expression of TJP1 mRNA; Hydrogen Peroxide results in decreased expression of TJP1 protein PMID:38438008 13932374 TJP1 tight junction protein 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240903 CTD MESH:D006861 SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 protein]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 protein] PMID:38438008 13932374 TJP1 tight junction protein 1 gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20210309 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of TJP1 mRNA; Lipopolysaccharides results in decreased expression of TJP1 protein PMID:32877744 13932374 TJP1 tight junction protein 1 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20210309 CTD MESH:D008070 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 protein]]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 protein]; MAP1LC3B protein affects the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of TJP1 protein]] PMID:32877744 13932374 TJP1 tight junction protein 1 gene CHEBI:16796 melatonin increases expression EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin results in increased expression of TJP1 protein PMID:37120089 13932374 TJP1 tight junction protein 1 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein] PMID:37120089 13932374 TJP1 tight junction protein 1 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D005978 Glutathione inhibits the reaction [Paraquat results in decreased expression of TJP1 protein] PMID:36615853 13932374 TJP1 tight junction protein 1 gene CHEBI:17394 N(5)-ethyl-L-glutamine multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C026166 theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 protein] PMID:38438008 13932374 TJP1 tight junction protein 1 gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein] PMID:37442268 13932374 TJP1 tight junction protein 1 gene CHEBI:27744 glyphosate decreases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in decreased expression of TJP1 mRNA PMID:31677563 13932374 TJP1 tight junction protein 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C059514 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of TJP1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of TJP1 protein] PMID:37955343 13932374 TJP1 tight junction protein 1 gene CHEBI:27915 melamine decreases expression EXP E RGD:6480464 20191114 CTD MESH:C011907 melamine results in decreased expression of TJP1 protein PMID:30055240 13932374 TJP1 tight junction protein 1 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C017947 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein] PMID:35381244 13932374 TJP1 tight junction protein 1 gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of TJP1 protein PMID:36754226 13932374 TJP1 tight junction protein 1 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D001564 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of TJP1 protein] PMID:36754226 13932374 TJP1 tight junction protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in decreased expression of TJP1 protein PMID:37108405 13932374 TJP1 tight junction protein 1 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Sodium Selenite affects the reaction [bisphenol A results in decreased expression of TJP1 protein] PMID:37108405 13932374 TJP1 tight junction protein 1 gene CHEBI:34905 paraquat decreases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in decreased expression of TJP1 protein PMID:36615853 13932374 TJP1 tight junction protein 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D010269 Glutathione inhibits the reaction [Paraquat results in decreased expression of TJP1 protein] PMID:36615853 13932374 TJP1 tight junction protein 1 gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein] PMID:37442268 13932374 TJP1 tight junction protein 1 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20200211 CTD MESH:C056933 fumonisin B1 results in decreased expression of TJP1 mRNA; fumonisin B1 results in decreased expression of TJP1 protein PMID:31557363|PMID:37955343 13932374 TJP1 tight junction protein 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C056933 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of TJP1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of TJP1 protein] PMID:37955343 13932374 TJP1 tight junction protein 1 gene CHEBI:41500 4-phenylbutyric acid multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C075773 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of TJP1 protein] PMID:36754226 13932374 TJP1 tight junction protein 1 gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D018038 Sodium Selenite affects the reaction [bisphenol A results in decreased expression of TJP1 protein] PMID:37108405 13932374 TJP1 tight junction protein 1 gene CHEBI:4948 Evodiamine multiple interactions EXP E RGD:6480464 20250114 CTD MESH:C049639 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 protein] PMID:39305878 13932374 TJP1 tight junction protein 1 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004178 Diquat results in decreased expression of TJP1 protein PMID:26338884 13932374 TJP1 tight junction protein 1 gene CHEBI:7719 ochratoxin A affects localization EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A affects the localization of TJP1 protein PMID:14994279 13932374 TJP1 tight junction protein 1 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C093642 SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 protein] PMID:38438008 13932374 TJP1 tight junction protein 1 gene CHEBI:9381 T-2 toxin decreases expression EXP E RGD:6480464 20250114 CTD MESH:D013605 T-2 Toxin results in decreased expression of TJP1 mRNA; T-2 Toxin results in decreased expression of TJP1 protein PMID:39305878 13932374 TJP1 tight junction protein 1 gene CHEBI:9381 T-2 toxin multiple interactions EXP E RGD:6480464 20250114 CTD MESH:D013605 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 protein] PMID:39305878 13932437 IL1RL1 interleukin 1 receptor like 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IL1RL1 mRNA PMID:35307453 13932478 FKBP9 FKBP prolyl isomerase 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FKBP9 mRNA PMID:35307453 13932580 S100A13 S100 calcium binding protein A13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100A13 mRNA PMID:35307453 13932597 CKMT1A creatine kinase, mitochondrial 1A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CKMT1A mRNA PMID:35307453 13932919 LIPM lipase family member M gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LIPM mRNA PMID:35307453 13933026 FCER2 Fc epsilon receptor II gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FCER2 mRNA PMID:35307453 13933079 GHR growth hormone receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GHR mRNA PMID:35307453 13933124 PLAG1 PLAG1 zinc finger gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLAG1 mRNA PMID:35307453 13933449 TMED6 transmembrane p24 trafficking protein 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMED6 mRNA PMID:35307453 13933457 COL4A4 collagen type IV alpha 4 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL4A4 mRNA PMID:35307453 13933573 ACLY ATP citrate lyase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACLY mRNA PMID:35307453 13933642 CLRN3 clarin 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLRN3 mRNA PMID:35307453 13933847 NPTX1 neuronal pentraxin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NPTX1 mRNA PMID:35307453 13933881 ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ELAPOR1 mRNA PMID:35307453 13933927 PTGDR2 prostaglandin D2 receptor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTGDR2 mRNA PMID:35307453 13933940 ACE angiotensin I converting enzyme gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACE mRNA PMID:35307453 13933940 ACE angiotensin I converting enzyme gene CHEBI:16480 nitric oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009569 ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] PMID:12672649 13934101 EBF2 EBF transcription factor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EBF2 mRNA PMID:35307453 13934245 APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of APOBEC1 mRNA PMID:35307453 13934399 SULT2B1 sulfotransferase family 2B member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SULT2B1 mRNA PMID:35307453 13934417 IL2RG interleukin 2 receptor subunit gamma gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of IL2RG mRNA PMID:21391292 13934417 IL2RG interleukin 2 receptor subunit gamma gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of IL2RG mRNA PMID:22497863 13934436 IL2RB interleukin 2 receptor subunit beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL2RB mRNA PMID:35307453 13934464 TIAM1 TIAM Rac1 associated GEF 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TIAM1 mRNA PMID:35307453 13934540 STRIP2 striatin interacting protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STRIP2 mRNA PMID:35307453 13934540 STRIP2 striatin interacting protein 2 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of STRIP2 mRNA PMID:35839969 13934691 PRKG1 protein kinase cGMP-dependent 1 gene CHEBI:16356 3',5'-cyclic GMP increases activity EXP E RGD:6480464 20191114 CTD MESH:D006152 Cyclic GMP results in increased activity of PRKG1 protein PMID:18037907 13934691 PRKG1 protein kinase cGMP-dependent 1 gene CHEBI:18421 superoxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013481 Superoxides affects the reaction [Nitroglycerin results in increased activity of PRKG1 protein] PMID:18037907 13934691 PRKG1 protein kinase cGMP-dependent 1 gene CHEBI:28787 nitroglycerin affects expression EXP E RGD:6480464 20191114 CTD MESH:D005996 Nitroglycerin affects the expression of PRKG1 mRNA; Nitroglycerin affects the expression of PRKG1 protein PMID:18037907 13934691 PRKG1 protein kinase cGMP-dependent 1 gene CHEBI:28787 nitroglycerin increases activity EXP E RGD:6480464 20191114 CTD MESH:D005996 Nitroglycerin results in increased activity of PRKG1 protein PMID:18037907 13934691 PRKG1 protein kinase cGMP-dependent 1 gene CHEBI:28787 nitroglycerin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005996 Superoxides affects the reaction [Nitroglycerin results in increased activity of PRKG1 protein] PMID:18037907 13934799 GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GABRB1 mRNA PMID:35307453 13934964 ISYNA1 inositol-3-phosphate synthase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ISYNA1 mRNA PMID:35307453 13934989 CLTRN collectrin, amino acid transport regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLTRN mRNA PMID:35307453 13935033 CFAP91 cilia and flagella associated protein 91 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP91 mRNA PMID:35307453 13935221 CACNA1D calcium voltage-gated channel subunit alpha1 D gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CACNA1D mRNA PMID:35307453 13935427 CDC26 cell division cycle 26 gene CHEBI:15428 glycine multiple interactions EXP E RGD:6480464 20240402 CTD MESH:D005998 Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CDC26 mRNA] PMID:35839969 13935427 CDC26 cell division cycle 26 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of CDC26 mRNA PMID:35839969 13935427 CDC26 cell division cycle 26 gene CHEBI:88522 Monobutylphthalate multiple interactions EXP E RGD:6480464 20240402 CTD MESH:C028577 Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CDC26 mRNA] PMID:35839969 13935506 PROSER1 proline and serine rich 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PROSER1 mRNA PMID:35307453 13935604 MEX3A mex-3 RNA binding family member A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MEX3A mRNA PMID:35307453 13935610 MAGOHB mago homolog B, exon junction complex subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MAGOHB mRNA PMID:35307453 13935638 FAM167A family with sequence similarity 167 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM167A mRNA PMID:35307453 13935646 PCDH7 protocadherin 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCDH7 mRNA PMID:35307453 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20210803 CTD MESH:C007262 deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] PMID:17656051 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20210803 CTD MESH:D015025 Zearalenone results in decreased expression of CYP19A1 protein PMID:29758222 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D015025 Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] PMID:17656051 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D015237 [epostane co-treated with Dinoprost] results in increased expression of CYP19A1 mRNA PMID:20739670 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:16598 DDE increases activity EXP E RGD:6480464 20210803 CTD MESH:D003633 Dichlorodiphenyl Dichloroethylene results in increased activity of CYP19A1 protein PMID:18195494 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:17347 testosterone multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D013739 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein PMID:16151981 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20210803 CTD MESH:D009538 Nicotine results in decreased expression of CYP19A1 mRNA PMID:32423882 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20210803 CTD MESH:D009538 Nicotine results in decreased expression of CYP19A1 mRNA PMID:32423882 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D001564 Benzo(a)pyrene inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein] PMID:28284726 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20210803 CTD MESH:C006780 bisphenol A results in increased expression of CYP19A1 protein PMID:28284726 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20210803 CTD MESH:C006780 bisphenol A inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein] PMID:28284726 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34027 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases activity EXP E RGD:6480464 20210803 CTD MESH:C016340 o,p'-DDT results in increased activity of CYP19A1 protein PMID:18195494 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34202 2,2',4,4',5,5'-hexachlorobiphenyl decreases activity EXP E RGD:6480464 20210803 CTD MESH:C014024 2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CYP19A1 protein PMID:16151981 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34202 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP E RGD:6480464 20210803 CTD MESH:C014024 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein PMID:16151981 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34211 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene increases activity EXP E RGD:6480464 20210803 CTD MESH:C054919 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased activity of CYP19A1 protein PMID:18195494 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl increases activity EXP E RGD:6480464 20210803 CTD MESH:C023035 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP19A1 protein PMID:16151981 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20210803 CTD MESH:C023035 [3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein PMID:16151981 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34372 4,4'-sulfonyldiphenol affects expression EXP E RGD:6480464 20210803 CTD MESH:C543008 bisphenol S affects the expression of CYP19A1 protein PMID:28352085 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:34372 4,4'-sulfonyldiphenol decreases expression EXP E RGD:6480464 20210803 CTD MESH:C543008 bisphenol S results in decreased expression of CYP19A1 mRNA PMID:28352085 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:47136 pentachlorobenzene increases expression EXP E RGD:6480464 20210803 CTD MESH:C003060 pentachlorobenzene results in increased expression of CYP19A1 protein PMID:21296658 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:5692 hexachlorobenzene decreases expression EXP E RGD:6480464 20210803 CTD MESH:D006581 Hexachlorobenzene results in decreased expression of CYP19A1 protein PMID:21296658 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:81584 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP E RGD:6480464 20210803 CTD MESH:C511295 2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of CYP19A1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP19A1 protein PMID:23146758|PMID:28284726 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:81584 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP E RGD:6480464 20210803 CTD MESH:C511295 2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]; Fadrozole inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein] PMID:23146758|PMID:28284726 13935674 CYP19A3 cytochrome P450 19A3 gene CHEBI:94355 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile multiple interactions EXP E RGD:6480464 20210803 CTD MESH:D017316 Fadrozole inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein] PMID:23146758 13935813 CDC42EP2 CDC42 effector protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDC42EP2 mRNA PMID:35307453 13935823 NNT nicotinamide nucleotide transhydrogenase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NNT mRNA; deoxynivalenol results in decreased expression of NNT protein PMID:35307453|PMID:38403181 13935931 PGF placental growth factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PGF mRNA PMID:35307453 13935931 PGF placental growth factor gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of PGF mRNA PMID:21391292 13936028 LRIF1 ligand dependent nuclear receptor interacting factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LRIF1 mRNA PMID:35307453 13936115 AMD1 adenosylmethionine decarboxylase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AMD1 mRNA PMID:35307453 13936139 NMT1 N-myristoyltransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NMT1 mRNA PMID:35307453 13936211 FKBP1A FKBP prolyl isomerase 1A gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of FKBP1A mRNA PMID:28069986 13936229 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PLCXD3 mRNA PMID:35307453 13936343 CLGN calmegin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CLGN mRNA PMID:35307453 13936424 FBXO32 F-box protein 32 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FBXO32 mRNA PMID:35307453 13936424 FBXO32 F-box protein 32 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of FBXO32 mRNA PMID:27617619 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:15846 NAD(+) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009243 NAD promotes the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] PMID:21296058 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:16240 hydrogen peroxide decreases activity EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in decreased activity of ALDH7A1 protein PMID:21296058 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein]; Mercaptoethanol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein]; NAD promotes the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] PMID:21296058 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:18320 1,4-dithiothreitol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004229 Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] PMID:21296058 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:41218 mercaptoethanol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008623 Mercaptoethanol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] PMID:21296058 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:42106 L-1,4-dithiothreitol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004229 Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] PMID:21296058 13936746 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:44215 NAD zwitterion multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009243 NAD promotes the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] PMID:21296058 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DNM1L mRNA PMID:35307453 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DNM1L mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DNM1L protein PMID:33493553 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:33234 vitamin E multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D024502 Vitamin E inhibits the reaction [Cyclosporine results in increased expression of DNM1L protein] PMID:23347876 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat results in increased expression of DNM1L mRNA; Paraquat results in increased expression of DNM1L protein PMID:34811946 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L protein]]; MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L protein]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]] PMID:34811946 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DNM1L mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DNM1L protein PMID:33493553 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20240903 CTD MESH:C056933 fumonisin B1 results in increased expression of DNM1L mRNA PMID:38705344 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C056933 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [fumonisin B1 results in increased expression of DNM1L mRNA] PMID:38705344 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L protein]] PMID:34811946 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:4031 cyclosporin A increases expression EXP E RGD:6480464 20191114 CTD MESH:D016572 Cyclosporine results in increased expression of DNM1L protein PMID:23347876 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:4031 cyclosporin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D016572 Vitamin E inhibits the reaction [Cyclosporine results in increased expression of DNM1L protein] PMID:23347876 13936768 FGD4 FYVE, RhoGEF and PH domain containing 4 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]] PMID:34811946 13936837 ADIPOR2 adiponectin receptor 2 gene CHEBI:16469 17beta-estradiol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased expression of ADIPOR2 protein PMID:28284726 13936837 ADIPOR2 adiponectin receptor 2 gene CHEBI:17347 testosterone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013739 Testosterone results in decreased expression of ADIPOR2 protein PMID:28284726 13936837 ADIPOR2 adiponectin receptor 2 gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of ADIPOR2 protein PMID:28284726 13936837 ADIPOR2 adiponectin receptor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of ADIPOR2 protein PMID:28284726 13936837 ADIPOR2 adiponectin receptor 2 gene CHEBI:5692 hexachlorobenzene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D006581 Hexachlorobenzene results in decreased expression of ADIPOR2 protein PMID:28284726 13936837 ADIPOR2 adiponectin receptor 2 gene CHEBI:81584 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP E RGD:6480464 20191114 CTD MESH:C511295 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ADIPOR2 protein PMID:28284726 13936954 HSP90AA1 heat shock protein 90 alpha family class A member 1 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D005978 [Glutathione co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA PMID:36615853 13936954 HSP90AA1 heat shock protein 90 alpha family class A member 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D010269 [Glutathione co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA PMID:36615853 13936964 PLD3 phospholipase D family member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLD3 mRNA PMID:35307453 13937040 LYPD5 LY6/PLAUR domain containing 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LYPD5 mRNA PMID:35307453 13937049 SKP2 S-phase kinase associated protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SKP2 mRNA PMID:35307453 13937075 TOMT transmembrane O-methyltransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20241224 CTD MESH:C007262 deoxynivalenol results in decreased expression of TOMT mRNA PMID:35307453 13937083 PKD2 polycystin 2, transient receptor potential cation channel gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PKD2 mRNA PMID:35307453 13937150 FBXO5 F-box protein 5 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of FBXO5 mRNA PMID:21852083 13937253 PTPN11 protein tyrosine phosphatase non-receptor type 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PTPN11 mRNA PMID:35307453 13937284 CCDC50 coiled-coil domain containing 50 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC50 mRNA PMID:35307453 13937543 PDE1A phosphodiesterase 1A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PDE1A mRNA PMID:35307453 13937601 XRCC1 X-ray repair cross complementing 1 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20201006 CTD MESH:C025589 ochratoxin A results in increased expression of XRCC1 protein PMID:32454083 13937721 IFT56 intraflagellar transport 56 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFT56 mRNA PMID:35307453 13937758 CYP21A1 cytochrome P450 family 21 subfamily A member 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CYP21A1 mRNA PMID:34933075 13937928 STK33 serine/threonine kinase 33 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STK33 mRNA PMID:35307453 13938173 RFX2 regulatory factor X2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RFX2 mRNA; deoxynivalenol results in decreased expression of RFX2 protein PMID:35307453|PMID:38403181 13938213 S100A8 S100 calcium binding protein A8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100A8 mRNA PMID:35307453 13938213 S100A8 S100 calcium binding protein A8 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of S100A8 mRNA PMID:34933075 13938339 CMKLR2 chemerin chemokine-like receptor 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CMKLR2 mRNA PMID:34933075 13938394 CALCB calcitonin-related polypeptide beta gene CHEBI:17489 3',5'-cyclic AMP increases abundance EXP E RGD:6480464 20191114 CTD MESH:D000242 CALCA protein results in increased abundance of Cyclic AMP PMID:18463244 13938394 CALCB calcitonin-related polypeptide beta gene CHEBI:28619 acrylamide increases expression EXP E RGD:6480464 20191114 CTD MESH:D020106 Acrylamide results in increased expression of CALCA protein PMID:30222996 13938412 E2F1 E2F transcription factor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of E2F1 mRNA PMID:35307453 13938614 NOP56 NOP56 ribonucleoprotein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NOP56 mRNA PMID:35307453 13938670 ISG12(A) putative ISG12(a) protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ISG12(A) mRNA PMID:35307453 13938780 NUPR1 nuclear protein 1, transcriptional regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NUPR1 mRNA PMID:35307453 13938806 TMEM53 transmembrane protein 53 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM53 mRNA PMID:35307453 13938817 PUS7 pseudouridine synthase 7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PUS7 mRNA PMID:35307453 13938846 MAP2K6 mitogen-activated protein kinase kinase 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAP2K6 mRNA PMID:35307453 13938894 TPO thyroid peroxidase gene CHEBI:132103 sodium perchlorate decreases activity EXP E RGD:6480464 20191114 CTD MESH:C031068 sodium perchlorate results in decreased activity of TPO protein PMID:23959146 13938894 TPO thyroid peroxidase gene CHEBI:28869 menadione decreases activity EXP E RGD:6480464 20191114 CTD MESH:D024483 Vitamin K 3 results in decreased activity of TPO protein PMID:11815678 13938894 TPO thyroid peroxidase gene CHEBI:34292 1,3-benzothiazole-2-thiol decreases activity EXP E RGD:6480464 20191114 CTD MESH:C005563 captax results in decreased activity of TPO protein PMID:23959146|PMID:25953703 13938894 TPO thyroid peroxidase gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of TPO mRNA PMID:16896063 13938894 TPO thyroid peroxidase gene CHEBI:45993 benzothiazole decreases activity EXP E RGD:6480464 20191114 CTD MESH:C005465 benzothiazole results in decreased activity of TPO protein PMID:25953703 13938894 TPO thyroid peroxidase gene CHEBI:50673 methimazole decreases activity EXP E RGD:6480464 20191114 CTD MESH:D008713 Methimazole results in decreased activity of TPO protein PMID:23959146 13938894 TPO thyroid peroxidase gene CHEBI:64215 2,3-dimethoxynaphthalene-1,4-dione decreases activity EXP E RGD:6480464 20191114 CTD MESH:C063002 2,3-dimethoxy-1,4-naphthoquinone results in decreased activity of TPO protein PMID:11815678 13938894 TPO thyroid peroxidase gene CHEBI:8502 6-propyl-2-thiouracil decreases activity EXP E RGD:6480464 20191114 CTD MESH:D011441 Propylthiouracil results in decreased activity of TPO protein PMID:23959146 13939000 SPRYD3 SPRY domain containing 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SPRYD3 mRNA PMID:35307453 13939165 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 gene CHEBI:10022 deoxynivalenol increases phosphorylation EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased phosphorylation of PRKAA1 protein PMID:35307453 13939165 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 gene CHEBI:16469 17beta-estradiol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased phosphorylation of and results in increased activity of PRKAA1 protein PMID:15967841 13939165 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PRKAA1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAA1 mRNA PMID:33592257|PMID:34416349 13939165 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PRKAA1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAA1 mRNA PMID:33592257|PMID:34416349 13939256 MOCS3 molybdenum cofactor synthesis 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MOCS3 mRNA PMID:35307453 13939397 LONRF2 LON peptidase N-terminal domain and ring finger 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LONRF2 mRNA PMID:35307453 13939474 ACOX2 acyl-CoA oxidase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACOX2 mRNA PMID:35307453 13939729 FAM110B family with sequence similarity 110 member B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM110B mRNA PMID:35307453 13939765 TCF23 transcription factor 23 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TCF23 mRNA PMID:35307453 13939780 PLA2G6 phospholipase A2 group VI gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLA2G6 mRNA PMID:35307453 13939886 RPL13A ribosomal protein L13a gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of RPL13A mRNA PMID:28069986 13940017 LARP4 La ribonucleoprotein 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LARP4 mRNA PMID:35307453 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RIPK3 mRNA PMID:35307453 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20230307 CTD MESH:D008550 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein] PMID:35665993 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A increases expression EXP E RGD:6480464 20230307 CTD MESH:C020806 tetrabromobisphenol A results in increased expression of RIPK3 mRNA; tetrabromobisphenol A results in increased expression of RIPK3 protein PMID:35665993 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C020806 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein] PMID:35665993 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in increased expression of RIPK3 mRNA; Cadmium Chloride results in increased expression of RIPK3 protein PMID:33626375 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20240903 CTD MESH:C056933 fumonisin B1 results in increased expression of RIPK3 mRNA; fumonisin B1 results in increased expression of RIPK3 protein PMID:38705344 13940123 RIPK3 receptor interacting serine/threonine kinase 3 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C056933 necrostatin-1 inhibits the reaction [fumonisin B1 results in increased expression of RIPK3 mRNA]; necrostatin-1 inhibits the reaction [fumonisin B1 results in increased expression of RIPK3 protein] PMID:38705344 13940164 MYEF2 myelin expression factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MYEF2 mRNA PMID:35307453 13940247 SETD9 SET domain containing 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SETD9 mRNA PMID:35307453 13940303 TCEA3 transcription elongation factor A3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TCEA3 mRNA PMID:35307453 13940339 ZBTB21 zinc finger and BTB domain containing 21 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZBTB21 protein PMID:37257635 13940349 LAX1 lymphocyte transmembrane adaptor 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of LAX1 mRNA PMID:34389318 13940839 CCT7 chaperonin containing TCP1 subunit 7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCT7 mRNA PMID:35307453 13940884 CD3E CD3 epsilon subunit of T-cell receptor complex gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CD3E mRNA PMID:34389318 13940898 MED15 mediator complex subunit 15 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MED15 mRNA PMID:35307453 13941100 TG thyroglobulin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TG mRNA PMID:35307453 13941211 TUBB tubulin beta class I gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in increased expression of TUBB3 mRNA PMID:35307453 13941219 MPST mercaptopyruvate sulfurtransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MPST mRNA PMID:35307453 13941229 CYP3A39 cytochrome P450 3A39 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of CYP3A39 mRNA PMID:34389318 13941229 CYP3A39 cytochrome P450 3A39 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D005978 Glutathione inhibits the reaction [Paraquat results in increased expression of CYP3A39 mRNA] PMID:36615853 13941229 CYP3A39 cytochrome P450 3A39 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in increased expression of CYP3A39 mRNA PMID:36615853 13941229 CYP3A39 cytochrome P450 3A39 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D010269 Glutathione inhibits the reaction [Paraquat results in increased expression of CYP3A39 mRNA] PMID:36615853 13941337 MRPS18B mitochondrial ribosomal protein S18B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS18B mRNA PMID:35307453 13941512 VLDLR very low density lipoprotein receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of VLDLR mRNA; deoxynivalenol results in decreased expression of VLDLR protein PMID:38403181 13941549 ZGRF1 zinc finger GRF-type containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZGRF1 mRNA PMID:35307453 13941592 RGS16 regulator of G protein signaling 16 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of RGS16 mRNA PMID:25455459 13941689 SLC25A19 solute carrier family 25 member 19 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC25A19 mRNA PMID:35307453 13941762 HYOU1 hypoxia up-regulated 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of HYOU1 mRNA; deoxynivalenol results in decreased expression of HYOU1 protein PMID:38403181 13941762 HYOU1 hypoxia up-regulated 1 gene CHEBI:35456 cadmium dichloride decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D019256 HYOU1 results in decreased susceptibility to Cadmium Chloride PMID:17464326 13941762 HYOU1 hypoxia up-regulated 1 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of HYOU1 mRNA PMID:35839969 13941875 TRAPPC5 trafficking protein particle complex subunit 5 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of TRAPPC5 mRNA PMID:28069986 13941889 ATP5PB ATP synthase peripheral stalk-membrane subunit b gene CHEBI:50842 norflurazon decreases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased expression of ATP5PB mRNA PMID:38432436 13942012 ASB9 ankyrin repeat and SOCS box containing 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASB9 mRNA PMID:35307453 13942080 PELI2 pellino E3 ubiquitin protein ligase family member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PELI2 mRNA PMID:35307453 13942090 DCLK1 doublecortin like kinase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DCLK1 mRNA PMID:35307453 13942236 ITGB4 integrin subunit beta 4 gene CHEBI:25434 bis(2-chloroethyl) sulfide affects expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas affects the expression of ITGB4 protein PMID:9285538 13942570 PRICKLE2 prickle planar cell polarity protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRICKLE2 mRNA PMID:35307453 13942801 REXO4 REX4 homolog, 3'-5' exonuclease gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of REXO4 mRNA PMID:35307453 13942872 UBAP1 ubiquitin associated protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBAP1 mRNA PMID:35307453 13942918 ATP7B ATPase copper transporting beta gene CHEBI:17489 3',5'-cyclic AMP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000242 Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein] PMID:21084060 13942918 ATP7B ATPase copper transporting beta gene CHEBI:28694 copper atom affects binding EXP E RGD:6480464 20191114 CTD MESH:D003300 Copper binds to ATP7B protein PMID:21084060 13942918 ATP7B ATPase copper transporting beta gene CHEBI:28694 copper atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003300 Cholera Toxin inhibits the reaction [Copper binds to ATP7B protein]; Colforsin inhibits the reaction [Copper binds to ATP7B protein]; Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein]; PRKACA protein inhibits the reaction [Copper binds to ATP7B protein] PMID:21084060 13942918 ATP7B ATPase copper transporting beta gene CHEBI:30052 copper(0) affects binding EXP E RGD:6480464 20191114 CTD MESH:D003300 Copper binds to ATP7B protein PMID:21084060 13942918 ATP7B ATPase copper transporting beta gene CHEBI:30052 copper(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003300 Cholera Toxin inhibits the reaction [Copper binds to ATP7B protein]; Colforsin inhibits the reaction [Copper binds to ATP7B protein]; Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein]; PRKACA protein inhibits the reaction [Copper binds to ATP7B protein] PMID:21084060 13942918 ATP7B ATPase copper transporting beta gene CHEBI:31429 colforsin daropate hydrochloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005576 Colforsin inhibits the reaction [Copper binds to ATP7B protein] PMID:21084060 13942990 TMEM39A transmembrane protein 39A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM39A mRNA PMID:35307453 13943227 CDC42EP3 CDC42 effector protein 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDC42EP3 mRNA PMID:35307453 13943254 CRPPA CDP-L-ribitol pyrophosphorylase A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CRPPA mRNA PMID:35307453 13943337 TMEM164 transmembrane protein 164 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM164 mRNA PMID:35307453 13943391 PHKA2 phosphorylase kinase regulatory subunit alpha 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PHKA2 mRNA PMID:35307453 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP1A1 mRNA; deoxynivalenol results in decreased expression of CYP1A1 protein PMID:38403181 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CYP1A1 mRNA PMID:35307453|PMID:35381244 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C007262 AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA] PMID:35381244 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl increases activity EXP E RGD:6480464 20191114 CTD MESH:C028451 3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl increases expression EXP E RGD:6480464 20191114 CTD MESH:C028451 3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein PMID:12970578|PMID:19608276 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C028451 alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein] PMID:12970578|PMID:19608276 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CYP1A1 mRNA PMID:34389318 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:16243 quercetin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin results in decreased activity of CYP1A1 protein PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein] PMID:12970578|PMID:19608276 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:18227 sterigmatocystin increases expression EXP E RGD:6480464 20191114 CTD MESH:D013241 Sterigmatocystin results in increased expression of CYP1A1 mRNA PMID:20929267 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:254496 7,12-dimethyltetraphene multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015127 7-ketocholesterol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein]; [Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein PMID:11042205 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP E RGD:6480464 20191114 CTD MESH:D013749 Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA; Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein PMID:16291828|PMID:16431846 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C017947 AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA] PMID:35381244 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:29865 benzo[a]pyrene increases expression EXP E RGD:6480464 20191114 CTD MESH:D001564 Benzo(a)pyrene results in increased expression of CYP1A1 protein PMID:18636242 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001564 7-ketocholesterol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein]; [Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein PMID:11042205 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl increases expression EXP E RGD:6480464 20191114 CTD MESH:C023035 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein PMID:16291828|PMID:19608276|PMID:22521609 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C023035 epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein] PMID:19608276|PMID:22521609 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate decreases activity EXP E RGD:6480464 20191114 CTD MESH:C045651 epigallocatechin gallate results in decreased activity of CYP1A1 protein PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C045651 epigallocatechin gallate results in decreased expression of CYP1A1 mRNA PMID:22521609 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C045651 epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA] PMID:12970578|PMID:22521609 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:64294 7-ketocholesterol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C003001 7-ketocholesterol inhibits the reaction [[Benzo(a)pyrene co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of CYP1A1 protein] PMID:11042205 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:6651 malathion decreases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in decreased expression of CYP1A1 mRNA PMID:31535366 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:76995 alpha-naphthoflavone decreases activity EXP E RGD:6480464 20191114 CTD MESH:C011512 alpha-naphthoflavone results in decreased activity of CYP1A1 protein PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:76995 alpha-naphthoflavone increases expression EXP E RGD:6480464 20191114 CTD MESH:C011512 alpha-naphthoflavone results in increased expression of CYP1A1 mRNA PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:76995 alpha-naphthoflavone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C011512 alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA] PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:77013 beta-naphthoflavone increases activity EXP E RGD:6480464 20191114 CTD MESH:D019324 beta-Naphthoflavone results in increased activity of CYP1A1 protein PMID:12970578|PMID:19464568 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:77013 beta-naphthoflavone increases expression EXP E RGD:6480464 20191114 CTD MESH:D019324 beta-Naphthoflavone results in increased expression of CYP1A1 mRNA; beta-Naphthoflavone results in increased expression of CYP1A1 protein PMID:12970578|PMID:19464568|PMID:19786062 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:77013 beta-naphthoflavone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019324 epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA] PMID:12970578 13943471 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:9171 skatole increases oxidation EXP E RGD:6480464 20191114 CTD MESH:D012862 CYP1A1 protein results in increased oxidation of Skatole PMID:30599194 13943610 HMGN3 high mobility group nucleosomal binding domain 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HMGN3 mRNA; deoxynivalenol results in decreased expression of HMGN3 protein PMID:35307453|PMID:38403181 13943666 LDLR low density lipoprotein receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of LDLR mRNA; deoxynivalenol results in decreased expression of LDLR protein PMID:38403181 13943666 LDLR low density lipoprotein receptor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LDLR mRNA PMID:35307453 13943666 LDLR low density lipoprotein receptor gene CHEBI:177470 Cloprostenol decreases expression EXP E RGD:6480464 20210907 CTD MESH:D003008 Cloprostenol results in decreased expression of LDLR mRNA PMID:15713365 13943666 LDLR low density lipoprotein receptor gene CHEBI:49040 ezetimibe increases expression EXP E RGD:6480464 20191114 CTD MESH:D000069438 Ezetimibe results in increased expression of LDLR mRNA PMID:17130282 13943666 LDLR low density lipoprotein receptor gene CHEBI:49040 ezetimibe multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069438 Simvastatin promotes the reaction [Ezetimibe results in increased expression of LDLR mRNA] PMID:17130282 13943666 LDLR low density lipoprotein receptor gene CHEBI:9150 simvastatin increases expression EXP E RGD:6480464 20191114 CTD MESH:D019821 Simvastatin results in increased expression of LDLR mRNA PMID:17130282 13943666 LDLR low density lipoprotein receptor gene CHEBI:9150 simvastatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019821 Simvastatin promotes the reaction [Ezetimibe results in increased expression of LDLR mRNA] PMID:17130282 13943703 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of PPM1D mRNA PMID:37706587 13943703 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of PPM1D mRNA] PMID:37706587 13943703 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of PPM1D mRNA] PMID:37706587 13943931 CPXM1 carboxypeptidase X, M14 family member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CPXM1 mRNA PMID:35307453 13944055 IFT88 intraflagellar transport 88 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IFT88 mRNA PMID:35307453 13944102 GEN1 GEN1 Holliday junction 5' flap endonuclease gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of GEN1 mRNA PMID:35307453 13944152 ACOD1 aconitate decarboxylase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACOD1 mRNA PMID:35307453 13944167 PLXND1 plexin D1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLXND1 mRNA PMID:35307453 13944240 CREB3L4 cAMP responsive element binding protein 3 like 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CREB3L4 mRNA PMID:35307453 13944350 TMEM9 transmembrane protein 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM9 mRNA PMID:35307453 13944656 CHIC2 cysteine rich hydrophobic domain 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CHIC2 mRNA PMID:35307453 13944803 GTPBP4 GTP binding protein 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GTPBP4 mRNA PMID:35307453 13944850 MRPL46 mitochondrial ribosomal protein L46 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL46 mRNA PMID:35307453 13945231 MFAP5 microfibril associated protein 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MFAP5 mRNA PMID:35307453 13945231 MFAP5 microfibril associated protein 5 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of MFAP5 mRNA PMID:21852083 13945257 GPR182 G protein-coupled receptor 182 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of GPR182 mRNA PMID:34389318 13945270 FOXO1 forkhead box O1 gene CHEBI:17154 nicotinamide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009536 Niacinamide results in increased expression of FOXO1 mRNA PMID:17851734 13945270 FOXO1 forkhead box O1 gene CHEBI:27881 resveratrol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased expression of FOXO1 mRNA PMID:17851734 13945270 FOXO1 forkhead box O1 gene CHEBI:9168 sirolimus affects localization EXP E RGD:6480464 20191114 CTD MESH:D020123 Sirolimus affects the localization of FOXO1 protein PMID:20622751 13945270 FOXO1 forkhead box O1 gene CHEBI:9168 sirolimus increases expression EXP E RGD:6480464 20191114 CTD MESH:D020123 Sirolimus results in increased expression of FOXO1 mRNA; Sirolimus results in increased expression of FOXO1 protein PMID:20622751 13945318 LOC100513296 transmembrane protease serine 11F gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMPRSS11F mRNA PMID:35307453 13945340 PRRT1 proline rich transmembrane protein 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of PRRT1 mRNA PMID:34933075 13945647 BCHE butyrylcholinesterase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BCHE mRNA PMID:35307453 13945647 BCHE butyrylcholinesterase gene CHEBI:17941 diisopropyl fluorophosphate decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007531 Isoflurophate results in decreased activity of BCHE protein PMID:4631366 13945647 BCHE butyrylcholinesterase gene CHEBI:196010 Butyrylcholine increases hydrolysis EXP E RGD:6480464 20231003 CTD MESH:C017100 BCHE protein results in increased hydrolysis of butyrylcholine PMID:4631366 13945647 BCHE butyrylcholinesterase gene CHEBI:27827 paraoxon decreases activity EXP E RGD:6480464 20191114 CTD MESH:D010261 Paraoxon results in decreased activity of BCHE protein PMID:4631366 13945647 BCHE butyrylcholinesterase gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of BCHE mRNA PMID:21852083 13945647 BCHE butyrylcholinesterase gene CHEBI:34690 dichlorvos decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004006 Dichlorvos results in decreased activity of BCHE protein PMID:4631366 13945647 BCHE butyrylcholinesterase gene CHEBI:41055 butyrylthiocholine increases hydrolysis EXP E RGD:6480464 20191114 CTD MESH:D002092 BCHE protein results in increased hydrolysis of Butyrylthiocholine PMID:22407886 13945671 SNX17 sorting nexin 17 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of SNX17 protein PMID:37257635 13945709 SHANK2 SH3 and multiple ankyrin repeat domains 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SHANK2 mRNA PMID:35307453 13945745 ZFTA zinc finger translocation associated gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZFTA mRNA PMID:35307453 13945923 TMEM212 transmembrane protein 212 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM212 mRNA PMID:35307453 13945943 ABCD4 ATP binding cassette subfamily D member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCD4 mRNA PMID:35307453 13945984 TMEM176A transmembrane protein 176A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM176A mRNA PMID:35307453 13946013 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENTPD1 mRNA PMID:35307453 13946013 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of ENTPD1 mRNA PMID:21852083 13946043 PM20D1 peptidase M20 domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PM20D1 mRNA PMID:35307453 13946100 SOX5 SRY-box transcription factor 5 gene CHEBI:10033 warfarin decreases expression EXP E RGD:6480464 20230905 CTD MESH:D014859 Warfarin results in decreased expression of SOX5 mRNA PMID:34520801 13946100 SOX5 SRY-box transcription factor 5 gene CHEBI:10033 warfarin multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D014859 Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]]; LRP6 protein affects the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]; SOX5 protein affects the reaction [Warfarin results in decreased expression of SOX9 mRNA]; SOX5 protein inhibits the reaction [Warfarin promotes the reaction [SOX9 protein binds to RUNX2 promoter]]; SOX5 protein inhibits the reaction [Warfarin results in decreased expression of and affects the localization of SOX9 protein]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]; SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 protein]; SOX5 protein promotes the reaction [Warfarin promotes the reaction [SOX9 protein binds to LRP6 promoter]]; SOX5 protein promotes the reaction [Warfarin results in increased expression of LRP6 protein]; Warfarin promotes the reaction [SOX5 protein binds to SOX9 promoter]; Warfarin results in decreased expression of and affects the localization of SOX5 protein PMID:34520801 13946100 SOX5 SRY-box transcription factor 5 gene CHEBI:31206 ammonium chloride multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D000643 Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]] PMID:34520801 13946375 EYA1 EYA transcriptional coactivator and phosphatase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EYA1 mRNA PMID:35307453 13946603 PDLIM7 PDZ and LIM domain 7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDLIM7 mRNA PMID:35307453 13946857 WDR31 WD repeat domain 31 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WDR31 mRNA PMID:35307453 13946945 CPAMD8 C3 and PZP like alpha-2-macroglobulin domain containing 8 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CPAMD8 mRNA PMID:34933075 13947011 SASS6 SAS-6 centriolar assembly protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of SASS6 mRNA; deoxynivalenol results in increased expression of SASS6 protein PMID:38403181 13947170 PHLDA2 pleckstrin homology like domain family A member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PHLDA2 mRNA PMID:35307453 13947314 HSPG2 heparan sulfate proteoglycan 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of HSPG2 mRNA; deoxynivalenol results in decreased expression of HSPG2 protein PMID:38403181 13947441 ELK3 ETS transcription factor ELK3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ELK3 mRNA PMID:35307453 13947453 N4BP2L2 NEDD4 binding protein 2 like 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of N4BP2L2 mRNA PMID:35307453 13947487 PLCL1 phospholipase C like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLCL1 mRNA PMID:35307453 13947534 WDR4 WD repeat domain 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of WDR4 mRNA PMID:35307453 13947571 DNAH12 dynein axonemal heavy chain 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAH12 mRNA PMID:35307453 13947706 GPR137B G protein-coupled receptor 137B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPR137B mRNA PMID:35307453 13948182 CLDN1 claudin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20210706 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLDN1 mRNA; deoxynivalenol results in decreased expression of CLDN1 protein PMID:32783910|PMID:35381244|PMID:36596350|PMID:37120089|PMID:37442268 13948182 CLDN1 claudin 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20210309 CTD MESH:C007262 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; [deoxynivalenol co-treated with Lipopolysaccharides] results in decreased expression of CLDN1 mRNA; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] PMID:32877744|PMID:35381244|PMID:37120089|PMID:37442268 13948182 CLDN1 claudin 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20210706 CTD MESH:D015025 Zearalenone results in decreased expression of CLDN1 protein PMID:32783910 13948182 CLDN1 claudin 1 gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of CLDN1 protein PMID:37659622 13948182 CLDN1 claudin 1 gene CHEBI:16240 hydrogen peroxide decreases expression EXP E RGD:6480464 20240903 CTD MESH:D006861 Hydrogen Peroxide results in decreased expression of CLDN1 mRNA; Hydrogen Peroxide results in decreased expression of CLDN1 protein PMID:38438008 13948182 CLDN1 claudin 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240903 CTD MESH:D006861 SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein] PMID:38438008 13948182 CLDN1 claudin 1 gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of CLDN1 mRNA; Lipopolysaccharides results in decreased expression of CLDN1 protein PMID:22092031|PMID:32877744|PMID:37271275 13948182 CLDN1 claudin 1 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20210309 CTD MESH:D008070 [deoxynivalenol co-treated with Lipopolysaccharides] results in decreased expression of CLDN1 mRNA; [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA] PMID:32877744|PMID:37271275 13948182 CLDN1 claudin 1 gene CHEBI:16796 melatonin increases expression EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin results in increased expression of CLDN1 protein PMID:37120089 13948182 CLDN1 claudin 1 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] PMID:37120089 13948182 CLDN1 claudin 1 gene CHEBI:17394 N(5)-ethyl-L-glutamine multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C026166 [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA] PMID:37271275|PMID:38438008 13948182 CLDN1 claudin 1 gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA] PMID:37999554 13948182 CLDN1 claudin 1 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein] PMID:36584959 13948182 CLDN1 claudin 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of CLDN1 mRNA PMID:18988085 13948182 CLDN1 claudin 1 gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] PMID:37442268 13948182 CLDN1 claudin 1 gene CHEBI:27744 glyphosate decreases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in decreased expression of CLDN1 mRNA; Glyphosate results in decreased expression of CLDN1 protein PMID:31677563|PMID:36584959 13948182 CLDN1 claudin 1 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein] PMID:36584959 13948182 CLDN1 claudin 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C059514 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of CLDN1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of CLDN1 protein] PMID:37955343 13948182 CLDN1 claudin 1 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C017947 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] PMID:35381244 13948182 CLDN1 claudin 1 gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of CLDN1 protein PMID:36754226 13948182 CLDN1 claudin 1 gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D001564 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of CLDN1 protein]; Sirolimus inhibits the reaction [Benzo(a)pyrene results in decreased expression of CLDN1 protein] PMID:36754226 13948182 CLDN1 claudin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in decreased expression of CLDN1 mRNA; bisphenol A results in decreased expression of CLDN1 protein PMID:37108405|PMID:37999554 13948182 CLDN1 claudin 1 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of CLDN1 protein] PMID:37108405|PMID:37999554 13948182 CLDN1 claudin 1 gene CHEBI:34905 paraquat decreases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in decreased expression of CLDN1 protein PMID:36615853 13948182 CLDN1 claudin 1 gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] PMID:37442268 13948182 CLDN1 claudin 1 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20200211 CTD MESH:C056933 fumonisin B1 results in decreased expression of CLDN1 mRNA; fumonisin B1 results in decreased expression of CLDN1 protein PMID:31557363|PMID:37955343 13948182 CLDN1 claudin 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C056933 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of CLDN1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of CLDN1 protein] PMID:37955343 13948182 CLDN1 claudin 1 gene CHEBI:41500 4-phenylbutyric acid multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C075773 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of CLDN1 protein] PMID:36754226 13948182 CLDN1 claudin 1 gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D018038 Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of CLDN1 protein] PMID:37108405 13948182 CLDN1 claudin 1 gene CHEBI:4948 Evodiamine multiple interactions EXP E RGD:6480464 20250114 CTD MESH:C049639 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 protein] PMID:39305878 13948182 CLDN1 claudin 1 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004178 Diquat results in decreased expression of CLDN1 protein PMID:26338884 13948182 CLDN1 claudin 1 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C093642 [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA] PMID:37271275|PMID:38438008 13948182 CLDN1 claudin 1 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D020123 Sirolimus inhibits the reaction [Benzo(a)pyrene results in decreased expression of CLDN1 protein] PMID:36754226 13948182 CLDN1 claudin 1 gene CHEBI:9381 T-2 toxin decreases expression EXP E RGD:6480464 20250114 CTD MESH:D013605 T-2 Toxin results in decreased expression of CLDN1 mRNA; T-2 Toxin results in decreased expression of CLDN1 protein PMID:39305878 13948182 CLDN1 claudin 1 gene CHEBI:9381 T-2 toxin multiple interactions EXP E RGD:6480464 20250114 CTD MESH:D013605 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 protein] PMID:39305878 13948182 CLDN1 claudin 1 gene CHEBI:9753 troglitazone decreases expression EXP E RGD:6480464 20230502 CTD MESH:C057693 Troglitazone results in decreased expression of CLDN1 mRNA; Troglitazone results in decreased expression of CLDN1 protein PMID:36596350 13948201 OPRD1 opioid receptor delta 1 gene CHEBI:32595 barium(0) affects transport EXP E RGD:6480464 20191114 CTD MESH:D001464 OPRD1 protein affects the transport of Barium PMID:12031848 13948201 OPRD1 opioid receptor delta 1 gene CHEBI:32595 barium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001464 Enkephalin, D-Penicillamine (2,5)- inhibits the reaction [OPRD1 protein results in increased transport of Barium] PMID:12031848 13948201 OPRD1 opioid receptor delta 1 gene CHEBI:73356 DPDPE multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020881 Enkephalin, D-Penicillamine (2,5)- inhibits the reaction [OPRD1 protein results in increased transport of Barium] PMID:12031848 13948259 UTP20 UTP20 small subunit processome component gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UTP20 mRNA PMID:35307453 13948360 INMT indolethylamine N-methyltransferase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of INMT mRNA PMID:35307453 13948372 S100A9 S100 calcium binding protein A9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100A9 mRNA PMID:35307453 13948372 S100A9 S100 calcium binding protein A9 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of S100A9 mRNA PMID:34933075 13948387 ARF6 ADP ribosylation factor 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARF6 mRNA PMID:35307453 13948399 COL9A2 collagen type IX alpha 2 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL9A2 mRNA PMID:35307453 13948622 FBLIM1 filamin binding LIM protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FBLIM1 mRNA PMID:35307453 13948688 TMEM255A transmembrane protein 255A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM255A mRNA PMID:35307453 13948710 CFAP299 cilia and flagella associated protein 299 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP299 mRNA PMID:35307453 13948756 TMEM125 transmembrane protein 125 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM125 mRNA PMID:35307453 13948817 UCP2 uncoupling protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UCP2 mRNA PMID:35307453 13948828 SERF2 small EDRK-rich factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SERF2 mRNA PMID:35307453 13949127 ACOX1 acyl-CoA oxidase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACOX1 mRNA PMID:34416349 13949127 ACOX1 acyl-CoA oxidase 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACOX1 mRNA PMID:34416349 13949127 ACOX1 acyl-CoA oxidase 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of ACOX1 mRNA PMID:16896063|PMID:17437637 13949127 ACOX1 acyl-CoA oxidase 1 gene CHEBI:64243 monosodium L-glutamate increases expression EXP E RGD:6480464 20200317 CTD MESH:D012970 Sodium Glutamate results in increased expression of ACOX1 mRNA PMID:31360149 13949232 DOP1B DOP1 leucine zipper like protein B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DOP1B mRNA PMID:35307453 13949357 KDM2B lysine demethylase 2B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KDM2B mRNA PMID:35307453 13949535 SULF1 sulfatase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SULF1 mRNA PMID:35307453 13949633 ZNF516 zinc finger protein 516 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF516 mRNA PMID:35307453 13949696 CDK2 cyclin dependent kinase 2 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat results in increased expression of CDK2 protein PMID:34811946 13949696 CDK2 cyclin dependent kinase 2 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 MYD88 protein affects the reaction [Paraquat results in increased expression of CDK2 protein] PMID:34811946 13949742 ZFAND4 zinc finger AN1-type containing 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZFAND4 mRNA PMID:35307453 13949772 DNAI3 dynein axonemal intermediate chain 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAI3 mRNA PMID:35307453 13949838 CDC42EP1 CDC42 effector protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDC42EP1 mRNA PMID:35307453 13949850 AKT2 AKT serine/threonine kinase 2 gene CHEBI:50842 norflurazon decreases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased phosphorylation of AKT2 protein PMID:38432436 13949850 AKT2 AKT serine/threonine kinase 2 gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of AKT2 mRNA PMID:31535366 13949904 EMC4 ER membrane protein complex subunit 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of EMC4 protein PMID:37257635 13949914 PURB purine rich element binding protein B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PURB mRNA PMID:35307453 13949933 TBC1D9 TBC1 domain family member 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TBC1D9 mRNA PMID:35307453 13949976 PBK PDZ binding kinase gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of PBK mRNA PMID:35307453 13949976 PBK PDZ binding kinase gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of PBK mRNA] PMID:21852083 13950093 ZXDC ZXD family zinc finger C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZXDC mRNA PMID:35307453 13950207 MKS1 MKS transition zone complex subunit 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MKS1 mRNA PMID:35307453 13950249 DENND2D DENN domain containing 2D gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DENND2D mRNA PMID:35307453 13950311 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CRISPLD2 mRNA PMID:35307453 13950311 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CRISPLD2 mRNA PMID:21852083 13950330 C3H16orf96 chromosome 3 C16orf96 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C3H16ORF96 mRNA PMID:35307453 13950379 SPATA18 spermatogenesis associated 18 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPATA18 mRNA PMID:35307453 13950626 PPP1R16A protein phosphatase 1 regulatory subunit 16A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPT mRNA PMID:35307453 13950626 PPP1R16A protein phosphatase 1 regulatory subunit 16A gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in increased activity of GPT protein] PMID:37999554 13950626 PPP1R16A protein phosphatase 1 regulatory subunit 16A gene CHEBI:33216 bisphenol A increases activity EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased activity of GPT protein PMID:37999554 13950626 PPP1R16A protein phosphatase 1 regulatory subunit 16A gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in increased activity of GPT protein] PMID:37999554 13950626 PPP1R16A protein phosphatase 1 regulatory subunit 16A gene CHEBI:64163 diquat increases activity EXP E RGD:6480464 20240903 CTD MESH:D004178 Diquat results in increased activity of GPT protein PMID:38567716 13950894 EFNA5 ephrin A5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EFNA5 mRNA PMID:35307453 13950910 DLG2 discs large MAGUK scaffold protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DLG2 mRNA PMID:35307453 13950910 DLG2 discs large MAGUK scaffold protein 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of DLG2 mRNA PMID:34933075 13951052 FNBP4 formin binding protein 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of FNBP4 mRNA; deoxynivalenol results in increased expression of FNBP4 protein PMID:38403181 13951187 MRPL18 mitochondrial ribosomal protein L18 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL18 mRNA PMID:35307453 13951300 AGPS alkylglycerone phosphate synthase gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of AGPS mRNA PMID:28069986 13951332 BCL3 BCL3 transcription coactivator gene CHEBI:16240 hydrogen peroxide decreases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in decreased expression of BCL3 mRNA PMID:37706587 13951332 BCL3 BCL3 transcription coactivator gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL3 mRNA] PMID:37706587 13951332 BCL3 BCL3 transcription coactivator gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL3 mRNA] PMID:37706587 13951510 SLC25A48 solute carrier family 25 member 48 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of SLC25A48 mRNA PMID:34933075 13951571 GRID2 glutamate ionotropic receptor delta type subunit 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of GRID2 mRNA PMID:34933075 13951601 CCR6 C-C motif chemokine receptor 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of CCR6 mRNA PMID:23326479 13951640 RGS8 regulator of G protein signaling 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RGS8 mRNA PMID:35307453 13951690 MSI2 musashi RNA binding protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MSI2 mRNA PMID:35307453 13951690 MSI2 musashi RNA binding protein 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of MSI2 mRNA] PMID:21852083 13951749 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of EZH2 mRNA PMID:26988607 13951806 ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADAMTS15 mRNA PMID:35307453 13952036 AKAP17A A-kinase anchoring protein 17A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AKAP17B mRNA PMID:35307453 13952138 CAPS calcyphosine gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CAPS mRNA PMID:35307453 13952205 MYO15B myosin XVB gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYO15B mRNA PMID:35307453 13952279 RIPK2 receptor interacting serine/threonine kinase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RIPK2 mRNA PMID:35307453 13952366 ABCA4 ATP binding cassette subfamily A member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCA4 mRNA PMID:35307453 13952499 C1S complement C1s gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of C1S mRNA PMID:22497863 13952578 FBXO4 F-box protein 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FBXO4 mRNA PMID:35307453 13952675 MAP2 microtubule associated protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAP2 mRNA PMID:35307453 13952949 CEBPD CCAAT enhancer binding protein delta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CEBPD mRNA PMID:35307453 13952949 CEBPD CCAAT enhancer binding protein delta gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CEBPD mRNA PMID:21852083 13953062 GLRX3 glutaredoxin 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GLRX3 mRNA PMID:35307453 13953237 ALPK1 alpha kinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALPK1 mRNA PMID:35307453 13953255 NLRC3 NLR family CARD domain containing 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NLRC3 mRNA PMID:35307453 13953255 NLRC3 NLR family CARD domain containing 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of NLRC3 mRNA PMID:34933075 13953314 IL34 interleukin 34 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL34 mRNA PMID:35307453 13953591 SLC9C1 solute carrier family 9 member C1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC9C1 mRNA PMID:35307453 13953661 KLF6 KLF transcription factor 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KLF6 mRNA PMID:35307453 13953669 ARID5A AT-rich interaction domain 5A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARID5A mRNA PMID:35307453 13953722 NAMPT nicotinamide phosphoribosyltransferase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NAMPT mRNA PMID:35307453 13953809 GLCCI1 glucocorticoid induced 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GLCCI1 mRNA PMID:35307453 13953979 RRP7A ribosomal RNA processing 7 homolog A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RRP7A mRNA PMID:35307453 13953997 BMPR1B bone morphogenetic protein receptor type 1B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BMPR1B mRNA PMID:35307453 13954110 PLA2G4E phospholipase A2 group IVE gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLA2G4E mRNA PMID:35307453 13954144 TAOK3 TAO kinase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TAOK3 mRNA PMID:35307453 13954199 ARHGAP28 Rho GTPase activating protein 28 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARHGAP28 mRNA; deoxynivalenol results in increased expression of ARHGAP28 protein PMID:35307453|PMID:38403181 13954283 CTH cystathionine gamma-lyase gene CHEBI:16236 ethanol increases activity EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased activity of CTH protein PMID:16792574 13954283 CTH cystathionine gamma-lyase gene CHEBI:16236 ethanol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000431 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of CTH protein PMID:16792574 13954283 CTH cystathionine gamma-lyase gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005492 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of CTH protein PMID:16792574 13954377 NRSN1 neurensin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NRSN1 mRNA PMID:35307453 13954556 ZNF704 zinc finger protein 704 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF704 mRNA PMID:35307453 13954605 DTNB dystrobrevin beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DTNB mRNA PMID:35307453 13954699 SFXN2 sideroflexin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SFXN2 mRNA PMID:35307453 13954847 SLITRK2 SLIT and NTRK like family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLITRK2 mRNA PMID:35307453 13954900 OXCT1 3-oxoacid CoA-transferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of OXCT1 mRNA PMID:35307453 13954964 KIF19 kinesin family member 19 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIF19 mRNA PMID:35307453 13955038 YARS2 tyrosyl-tRNA synthetase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of YARS2 mRNA PMID:35307453 13955051 STAM signal transducing adaptor molecule gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STAM mRNA PMID:35307453 13955160 IL9R interleukin 9 receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL9R mRNA PMID:35307453 13955274 LIPA lipase A, lysosomal acid type gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LIPA mRNA PMID:35307453 13955299 KITLG KIT ligand gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KITLG mRNA PMID:35307453 13955321 ATM ATM serine/threonine kinase gene CHEBI:10022 deoxynivalenol increases phosphorylation EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol results in increased phosphorylation of ATM protein PMID:38104654 13955321 ATM ATM serine/threonine kinase gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20240806 CTD MESH:C007262 ATM protein promotes the reaction [deoxynivalenol results in increased phosphorylation of CHEK2 protein]; Caffeine inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATM protein] PMID:38104654 13955321 ATM ATM serine/threonine kinase gene CHEBI:27732 caffeine multiple interactions EXP E RGD:6480464 20240806 CTD MESH:D002110 Caffeine inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATM protein] PMID:38104654 13955480 CYC1 cytochrome c1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CYC1 mRNA PMID:35307453 13955511 TMEM151A transmembrane protein 151A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM151A mRNA PMID:35307453 13955517 SLC8B1 solute carrier family 8 member B1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC8B1 mRNA PMID:35307453 13955555 KIAA1549 KIAA1549 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIAA1549 mRNA PMID:35307453 13955605 BMP8B bone morphogenetic protein 8b gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BMP8B mRNA PMID:35307453 13955656 KATNAL2 katanin catalytic subunit A1 like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KATNAL2 mRNA PMID:35307453 13955682 AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AGPAT4 mRNA PMID:35307453 13955872 UBE2C ubiquitin conjugating enzyme E2 C gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of UBE2C mRNA PMID:21852083 13955889 NFAT5 nuclear factor of activated T cells 5 gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of NFAT5 mRNA PMID:21391292 13955985 DZANK1 double zinc ribbon and ankyrin repeat domains 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DZANK1 mRNA PMID:35307453 13956042 LOC100516084 cytoplasmic tRNA 2-thiolation protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CTU1 mRNA PMID:35307453 13956140 GNRHR2 gonadotropin releasing hormone receptor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GNRHR2 mRNA PMID:35307453 13956236 FOXO4 forkhead box O4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FOXO4 mRNA PMID:35307453 13956337 CILP2 cartilage intermediate layer protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CILP2 mRNA PMID:35307453 13956414 CLHC1 clathrin heavy chain linker domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLHC1 mRNA PMID:35307453 13956479 PROM2 prominin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PROM2 mRNA PMID:35307453 13956671 PHKG2 phosphorylase kinase catalytic subunit gamma 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PHKG2 mRNA PMID:35307453 13956727 SGTB small glutamine rich tetratricopeptide repeat co-chaperone beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SGTB mRNA PMID:35307453 13956781 MFN1 mitofusin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20200714 CTD MESH:C007262 deoxynivalenol results in decreased expression of MFN1 protein PMID:32302720 13956781 MFN1 mitofusin 1 gene CHEBI:15428 glycine multiple interactions EXP E RGD:6480464 20240402 CTD MESH:D005998 Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 protein] PMID:35839969 13956781 MFN1 mitofusin 1 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA] PMID:36584959 13956781 MFN1 mitofusin 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN1 protein PMID:33493553|PMID:33592257 13956781 MFN1 mitofusin 1 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of MFN1 mRNA PMID:36584959 13956781 MFN1 mitofusin 1 gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA] PMID:36584959 13956781 MFN1 mitofusin 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN1 protein PMID:33493553|PMID:33592257 13956781 MFN1 mitofusin 1 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of MFN1 mRNA; monobutyl phthalate results in decreased expression of MFN1 protein PMID:35839969 13956781 MFN1 mitofusin 1 gene CHEBI:88522 Monobutylphthalate multiple interactions EXP E RGD:6480464 20240402 CTD MESH:C028577 Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 protein] PMID:35839969 13956884 STK17A serine/threonine kinase 17a gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STK17A mRNA PMID:35307453 13956957 RNF186 ring finger protein 186 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of RNF186 mRNA PMID:34933075 13956991 SLC7A1 solute carrier family 7 member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC7A1 mRNA PMID:35307453 13956991 SLC7A1 solute carrier family 7 member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20210406 CTD MESH:C006780 bisphenol A results in increased expression of SLC7A1 mRNA PMID:32710935 13956991 SLC7A1 solute carrier family 7 member 1 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20210706 CTD MESH:C056933 fumonisin B1 results in decreased expression of SLC7A1 mRNA PMID:33443779 13957040 EXD3 exonuclease 3'-5' domain containing 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EXD3 mRNA PMID:35307453 13957064 YIF1A Yip1 interacting factor homolog A, membrane trafficking protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of YIF1A mRNA PMID:35307453 13957089 LPL lipoprotein lipase gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of LPL mRNA] PMID:21852083 13957283 LSG1 large 60S subunit nuclear export GTPase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LSG1 mRNA PMID:35307453 13957389 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BUB1B mRNA PMID:35307453 13957473 PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PYROXD2 mRNA PMID:35307453 13957641 SUSD2 sushi domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SUSD2 mRNA PMID:35307453 13957734 RCN2 reticulocalbin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RCN2 mRNA PMID:35307453 13957825 ESRP2 epithelial splicing regulatory protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ESRP2 mRNA PMID:35307453 13958022 GPR119 G protein-coupled receptor 119 gene CHEBI:64243 monosodium L-glutamate affects expression EXP E RGD:6480464 20200317 CTD MESH:D012970 Sodium Glutamate affects the expression of GPR119 mRNA PMID:31360149 13958022 GPR119 G protein-coupled receptor 119 gene CHEBI:64243 monosodium L-glutamate multiple interactions EXP E RGD:6480464 20200317 CTD MESH:D012970 Dietary Fats affects the reaction [Sodium Glutamate affects the expression of GPR119 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of GPR119 mRNA] PMID:31360149 13958158 KLF11 KLF transcription factor 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KLF11 mRNA PMID:35307453 13958192 KLF10 KLF transcription factor 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KLF10 mRNA PMID:35307453 13958304 TSPAN12 tetraspanin 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TSPAN12 mRNA PMID:35307453 13958347 EML2 EMAP like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EML2 mRNA PMID:35307453 13958420 G6PD glucose-6-phosphate dehydrogenase gene CHEBI:34905 paraquat affects activity EXP E RGD:6480464 20191114 CTD MESH:D010269 Paraquat affects the activity of G6PD protein PMID:11814328 13958481 IL4I1 interleukin 4 induced 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IL4I1 mRNA PMID:35307453 13958536 ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ST3GAL3 mRNA PMID:35307453 13958588 ERP27 endoplasmic reticulum protein 27 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ERP27 mRNA PMID:35307453 13958698 TMEM59 transmembrane protein 59 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM59 mRNA PMID:35307453 13958725 ARFGAP1 ADP ribosylation factor GTPase activating protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARFGAP1 mRNA PMID:35307453 13958766 ENKUR enkurin, TRPC channel interacting protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENKUR mRNA PMID:35307453 13958796 SERPINI1 serpin family I member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SERPINI1 mRNA PMID:35307453 13958910 BGN biglycan gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BGN mRNA PMID:35307453 13958926 NGF nerve growth factor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NGF mRNA PMID:35307453 13958956 METRNL meteorin like, glial cell differentiation regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of METRNL mRNA PMID:35307453 13958985 GAA alpha glucosidase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GAA mRNA PMID:35307453 13959074 MELTF melanotransferrin gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of MELTF mRNA PMID:35307453 13959150 UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UAP1L1 mRNA PMID:35307453 13959177 PHF7 PHD finger protein 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PHF7 mRNA PMID:35307453 13959317 ZCCHC8 zinc finger CCHC-type containing 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZCCHC8 mRNA PMID:35307453 13959489 EXOSC10 exosome component 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EXOSC10 mRNA PMID:35307453 13959540 GSR glutathione-disulfide reductase gene CHEBI:10022 deoxynivalenol decreases activity EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased activity of GSR protein PMID:29109043 13959540 GSR glutathione-disulfide reductase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GSR mRNA PMID:35307453 13959540 GSR glutathione-disulfide reductase gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007262 Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]] PMID:29109043 13959540 GSR glutathione-disulfide reductase gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015025 Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]] PMID:29109043 13959540 GSR glutathione-disulfide reductase gene CHEBI:16236 ethanol increases activity EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased activity of GSR protein PMID:16792574 13959540 GSR glutathione-disulfide reductase gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of GSR mRNA PMID:16792574 13959540 GSR glutathione-disulfide reductase gene CHEBI:16236 ethanol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000431 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSR protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSR mRNA PMID:16792574 13959540 GSR glutathione-disulfide reductase gene CHEBI:27470 folic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:D005492 Folic Acid deficiency results in increased activity of GSR protein PMID:16792574 13959540 GSR glutathione-disulfide reductase gene CHEBI:27470 folic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D005492 Folic Acid deficiency results in increased expression of GSR mRNA PMID:16792574 13959540 GSR glutathione-disulfide reductase gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005492 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSR protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSR mRNA PMID:16792574 13959540 GSR glutathione-disulfide reductase gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]] PMID:29109043 13959540 GSR glutathione-disulfide reductase gene CHEBI:34905 paraquat affects activity EXP E RGD:6480464 20191114 CTD MESH:D010269 Paraquat affects the activity of GSR protein PMID:11814328 13959540 GSR glutathione-disulfide reductase gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C056933 Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]] PMID:29109043 13959585 DSCC1 DNA replication and sister chromatid cohesion 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DSCC1 mRNA PMID:35307453 13959693 DNAJC15 DnaJ heat shock protein family (Hsp40) member C15 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DNAJC15 mRNA PMID:35307453 13959710 TICAM2 toll like receptor adaptor molecule 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TICAM2 mRNA PMID:35307453 13959832 GCHFR GTP cyclohydrolase I feedback regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GCHFR mRNA PMID:35307453 13959839 CLU clusterin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLU mRNA PMID:35307453 13959839 CLU clusterin gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of CLU mRNA PMID:28069986 13959839 CLU clusterin gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of CLU mRNA PMID:18988085 13959839 CLU clusterin gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol promotes the reaction [Dietary Fats results in increased expression of CLU mRNA] PMID:21852083 13960009 CSTF2 cleavage stimulation factor subunit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CSTF2 mRNA PMID:35307453 13960040 NSA2 NSA2 ribosome biogenesis factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NSA2 mRNA PMID:35307453 13960175 PAQR5 progestin and adipoQ receptor family member 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PAQR5 mRNA PMID:35307453 13960385 TLN2 talin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TLN2 mRNA PMID:35307453 13960701 CXCL14 C-X-C motif chemokine ligand 14 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CXCL14 mRNA PMID:35307453 13960701 CXCL14 C-X-C motif chemokine ligand 14 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of CXCL14 mRNA PMID:34933075 13960701 CXCL14 C-X-C motif chemokine ligand 14 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CXCL14 mRNA PMID:34389318 13960878 ABCA7 ATP binding cassette subfamily A member 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCA7 mRNA PMID:35307453 13960993 CUTC cutC copper transporter gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CUTC mRNA PMID:35307453 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20221206 CTD MESH:C007262 deoxynivalenol results in increased expression of NFKB1 mRNA PMID:35314294 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:15379 dioxygen affects localization EXP E RGD:6480464 20191114 CTD MESH:D010100 Oxygen deficiency affects the localization of NFKB1 protein PMID:9728040 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:18050 L-glutamine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D005973 Glutamine inhibits the reaction [bisphenol A results in increased expression of NFKB1 mRNA] PMID:38154151 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NFKB1 mRNA PMID:33592257|PMID:34416349 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of NFKB1 mRNA PMID:31677563|PMID:35388968 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of NFKB1 mRNA PMID:38154151 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Glutamine inhibits the reaction [bisphenol A results in increased expression of NFKB1 mRNA] PMID:38154151 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NFKB1 mRNA PMID:33592257|PMID:34416349 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20200714 CTD MESH:C056933 fumonisin B1 results in increased expression of NFKB1 mRNA; fumonisin B1 results in increased expression of NFKB1 protein PMID:32198028 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20200714 CTD MESH:C056933 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of NFKB1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [fumonisin B1 results in increased expression of NFKB1 protein] PMID:32198028 13961142 NFKB1 nuclear factor kappa B subunit 1 gene CHEBI:77732 cadmium nitrate affects expression EXP E RGD:6480464 20191114 CTD MESH:C035196 cadmium nitrate affects the expression of NFKB1 mRNA PMID:29421334 13961167 KLK7 kallikrein related peptidase 7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KLK7 mRNA PMID:35307453 13961258 EGFR epidermal growth factor receptor gene CHEBI:16240 hydrogen peroxide decreases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in decreased expression of EGFR mRNA PMID:37706587 13961258 EGFR epidermal growth factor receptor gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of EGFR mRNA] PMID:37706587 13961258 EGFR epidermal growth factor receptor gene CHEBI:16336 hyaluronic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006820 EGFR protein affects the chemical synthesis of and affects the localization of Hyaluronic Acid PMID:21520325 13961258 EGFR epidermal growth factor receptor gene CHEBI:17026 progesterone affects chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:D011374 EGFR protein affects the chemical synthesis of Progesterone PMID:21520325 13961258 EGFR epidermal growth factor receptor gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of EGFR mRNA] PMID:37706587 13961335 TESK2 testis associated actin remodelling kinase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TESK2 mRNA PMID:35307453 13961418 LOC100512977 KDEL motif-containing protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EXPH5 mRNA PMID:35307453 13961607 SNRPN small nuclear ribonucleoprotein polypeptide N gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SNRPN mRNA PMID:35307453 13961838 EHD1 EH domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EHD1 mRNA PMID:35307453 13961886 SHMT1 serine hydroxymethyltransferase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of SHMT1 mRNA] PMID:21852083 13961994 XPO5 exportin 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of XPO5 mRNA; bisphenol A results in decreased expression of XPO5 protein PMID:31266599 13961994 XPO5 exportin 5 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006780 [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of XPO5 protein PMID:31266599 13961994 XPO5 exportin 5 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C020806 tetrabromobisphenol A results in decreased expression of XPO5 protein PMID:31266599 13961994 XPO5 exportin 5 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C020806 [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 protein PMID:31266599 13961994 XPO5 exportin 5 gene CHEBI:35004 Tetrachlorobisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C041181 tetrachlorodian results in decreased expression of XPO5 mRNA; tetrachlorodian results in decreased expression of XPO5 protein PMID:31266599 13961994 XPO5 exportin 5 gene CHEBI:35004 Tetrachlorobisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C041181 [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrachlorodian] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrachlorodian] results in decreased expression of XPO5 protein PMID:31266599 13962072 NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 gene CHEBI:50842 norflurazon decreases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased expression of NDUFS2 mRNA PMID:38432436 13962094 ACAT2 acetyl-CoA acetyltransferase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACAT2 mRNA PMID:35307453 13962107 AKAP11 A-kinase anchoring protein 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AKAP11 mRNA PMID:35307453 13962166 OAF out at first homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of OAF mRNA PMID:35307453 13962403 MVD mevalonate diphosphate decarboxylase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MVD mRNA PMID:35307453 13962421 TBC1D2 TBC1 domain family member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TBC1D2 mRNA PMID:35307453 13962552 ACBD3 acyl-CoA binding domain containing 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACBD3 mRNA PMID:35307453 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of HSD17B1 mRNA PMID:28069986 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:16422 androst-4-ene-3,17-dione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000735 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Androstenedione] results in increased activity of HSD17B1 protein PMID:16151981 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:34202 2,2',4,4',5,5'-hexachlorobiphenyl decreases activity EXP E RGD:6480464 20191114 CTD MESH:C014024 2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of HSD17B1 protein PMID:16151981 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:34202 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C014024 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Androstenedione] results in increased activity of HSD17B1 protein PMID:16151981 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl decreases activity EXP E RGD:6480464 20191114 CTD MESH:C023035 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of HSD17B1 protein PMID:16151981 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:5692 hexachlorobenzene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D006581 Hexachlorobenzene results in decreased expression of HSD17B1 protein PMID:21296658 13962593 HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 gene CHEBI:81584 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP E RGD:6480464 20191114 CTD MESH:C511295 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of HSD17B1 protein PMID:21871953 13962642 HSPB1 heat shock protein family B (small) member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HSPB1 mRNA PMID:35307453 13962642 HSPB1 heat shock protein family B (small) member 1 gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased expression of HSP27 protein PMID:12915104 13962647 SLA-8 MHC class I antigen 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLA-8 mRNA PMID:35307453 13962721 PSMB2 proteasome 20S subunit beta 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMB2 mRNA PMID:35307453 13962801 SARS1 seryl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SARS1 mRNA PMID:35307453 13962925 ADAM11 ADAM metallopeptidase domain 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADAM11 mRNA PMID:35307453 13963117 DCTN4 dynactin subunit 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DCTN4 mRNA PMID:35307453 13963117 DCTN4 dynactin subunit 4 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA]; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA] PMID:34811946 13963117 DCTN4 dynactin subunit 4 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA] PMID:34811946 13963117 DCTN4 dynactin subunit 4 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA] PMID:34811946 13963222 RPGRIP1L RPGRIP1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RPGRIP1L mRNA PMID:35307453 13963339 CDC42BPA CDC42 binding protein kinase alpha gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CDC42BPA mRNA PMID:21852083 13963561 ERI3 ERI1 exoribonuclease family member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ERI3 mRNA PMID:35307453 13963634 PRSS27 serine protease 27 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PRSS27 mRNA PMID:35307453 13963846 RALB RAS like proto-oncogene B gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of RALB mRNA PMID:34389318 13963878 ZBTB33 zinc finger and BTB domain containing 33 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZBTB33 mRNA PMID:35307453 13963919 GPATCH4 G-patch domain containing 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GPATCH4 mRNA PMID:35307453 13963971 SLC44A3 solute carrier family 44 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC44A3 mRNA PMID:35307453 13964011 MOGAT2 monoacylglycerol O-acyltransferase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MOGAT2 mRNA PMID:35307453 13964249 KIAA2012 KIAA2012 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIAA2012 mRNA PMID:35307453 13964683 BBS1 Bardet-Biedl syndrome 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BBS1 mRNA PMID:35307453 13964748 CFAP95 cilia and flagella associated protein 95 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP95 mRNA PMID:35307453 13964818 ALDH1L2 aldehyde dehydrogenase 1 family member L2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALDH1L2 mRNA PMID:35307453 13964845 SDC1 syndecan 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SDC1 mRNA PMID:35307453 13964845 SDC1 syndecan 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of SDC1 protein PMID:37257635 13964865 RGS14 regulator of G protein signaling 14 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RGS14 mRNA PMID:35307453 13964892 SH2D3A SH2 domain containing 3A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SH2D3A mRNA PMID:35307453 13964972 MYH7B myosin heavy chain 7B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYH7B mRNA PMID:35307453 13965036 RAB38 RAB38, member RAS oncogene family gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of RAB38 mRNA PMID:21852083 13965100 LYZ lysozyme gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LYZ mRNA PMID:35307453 13965115 URB2 URB2 ribosome biogenesis homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of URB2 mRNA PMID:35307453 13965129 PDLIM1 PDZ and LIM domain 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDLIM1 mRNA PMID:35307453 13965199 GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GNPTAB mRNA PMID:35307453 13965268 H2BC21 H2B clustered histone 21 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of H2BC21 mRNA PMID:35307453 13965298 CYP2D6 cytochrome P450 family 2 subfamily D member 6 gene CHEBI:17933 calcidiol increases hydroxylation EXP E RGD:6480464 20210209 CTD MESH:D002112 CYP2D6 protein results in increased hydroxylation of Calcifediol PMID:11880238 13965298 CYP2D6 cytochrome P450 family 2 subfamily D member 6 gene CHEBI:223316 (+)-artemisinin increases expression EXP E RGD:6480464 20241001 CTD MESH:C031327 artemisinin results in increased expression of CYP2D6 mRNA PMID:24176340 13965298 CYP2D6 cytochrome P450 family 2 subfamily D member 6 gene CHEBI:27300 vitamin D increases hydroxylation EXP E RGD:6480464 20210209 CTD MESH:D014807 CYP2D6 protein results in increased hydroxylation of Vitamin D PMID:11880238 13965298 CYP2D6 cytochrome P450 family 2 subfamily D member 6 gene CHEBI:31186 alfacalcidol increases hydroxylation EXP E RGD:6480464 20210209 CTD MESH:C008088 CYP2D6 protein results in increased hydroxylation of alfacalcidol PMID:11880238 13965298 CYP2D6 cytochrome P450 family 2 subfamily D member 6 gene CHEBI:6358 lactucin increases expression EXP E RGD:6480464 20241001 CTD MESH:C516715 lactucin results in increased expression of CYP2D6 mRNA PMID:24176340 13965298 CYP2D6 cytochrome P450 family 2 subfamily D member 6 gene CHEBI:9055 scoparone increases expression EXP E RGD:6480464 20241001 CTD MESH:C018145 scoparone results in increased expression of CYP2D6 mRNA PMID:24176340 13965737 EPHA7 EPH receptor A7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EPHA7 mRNA PMID:35307453 13965793 PLSCR4 phospholipid scramblase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLSCR4 mRNA PMID:35307453 13965880 ANO5 anoctamin 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ANO5 mRNA PMID:35307453 13965915 NEMP1 nuclear envelope integral membrane protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NEMP1 mRNA PMID:35307453 13965986 ARSA arylsulfatase A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARSA mRNA PMID:35307453 13966093 OGDH oxoglutarate dehydrogenase gene CHEBI:18291 manganese atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008345 Manganese inhibits the reaction [Calcium results in increased activity of OGDH protein] PMID:20800605 13966093 OGDH oxoglutarate dehydrogenase gene CHEBI:22984 calcium atom increases activity EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in increased activity of OGDH protein PMID:20800605 13966093 OGDH oxoglutarate dehydrogenase gene CHEBI:22984 calcium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 Manganese inhibits the reaction [Calcium results in increased activity of OGDH protein] PMID:20800605 13966093 OGDH oxoglutarate dehydrogenase gene CHEBI:29320 calcium(0) increases activity EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in increased activity of OGDH protein PMID:20800605 13966093 OGDH oxoglutarate dehydrogenase gene CHEBI:29320 calcium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 Manganese inhibits the reaction [Calcium results in increased activity of OGDH protein] PMID:20800605 13966093 OGDH oxoglutarate dehydrogenase gene CHEBI:35154 manganese(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008345 Manganese inhibits the reaction [Calcium results in increased activity of OGDH protein] PMID:20800605 13966178 VPS9D1 VPS9 domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VPS9D1 mRNA PMID:35307453 13966324 CCR5 C-C motif chemokine receptor 5 gene CHEBI:15553 prostaglandin F2alpha increases expression EXP E RGD:6480464 20191114 CTD MESH:D015237 Dinoprost results in increased expression of CCR5 mRNA PMID:21505051 13966324 CCR5 C-C motif chemokine receptor 5 gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015237 epostane promotes the reaction [Dinoprost results in increased expression of CCR5 mRNA] PMID:21505051 13966324 CCR5 C-C motif chemokine receptor 5 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of CCR5 mRNA PMID:27617619 13966324 CCR5 C-C motif chemokine receptor 5 gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of CCR5 mRNA PMID:18790026 13966336 STAR steroidogenic acute regulatory protein gene CHEBI:177470 Cloprostenol decreases expression EXP E RGD:6480464 20210907 CTD MESH:D003008 Cloprostenol results in decreased expression of STAR mRNA; Cloprostenol results in decreased expression of STAR protein PMID:15713365 13966336 STAR steroidogenic acute regulatory protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of STAR mRNA PMID:29544186 13966336 STAR steroidogenic acute regulatory protein gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006780 [bisphenol A co-treated with fisetin] results in decreased expression of STAR mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of STAR mRNA] PMID:29544186 13966336 STAR steroidogenic acute regulatory protein gene CHEBI:42567 fisetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C017875 [bisphenol A co-treated with fisetin] results in decreased expression of STAR mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of STAR mRNA] PMID:29544186 13966347 MRTFA myocardin related transcription factor A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRTFA mRNA PMID:35307453 13966425 CNN3 calponin 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CNN3 mRNA PMID:35307453 13966448 ZC3H15 zinc finger CCCH-type containing 15 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZC3H15 mRNA PMID:35307453 13966564 PSMC2 proteasome 26S subunit, ATPase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMC2 mRNA PMID:35307453 13966638 SIRT1 sirtuin 1 gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20230704 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of SIRT1 protein PMID:36549457 13966638 SIRT1 sirtuin 1 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D008070 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]]; Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein] PMID:36549457 13966638 SIRT1 sirtuin 1 gene CHEBI:17154 nicotinamide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009536 Niacinamide results in decreased expression of SIRT1 mRNA PMID:17851734 13966638 SIRT1 sirtuin 1 gene CHEBI:27881 resveratrol increases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in increased expression of SIRT1 mRNA; Resveratrol results in increased expression of SIRT1 protein PMID:17037214|PMID:17851734|PMID:23065251 13966638 SIRT1 sirtuin 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C059514 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]]; Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein] PMID:36549457 13966638 SIRT1 sirtuin 1 gene CHEBI:90369 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C550547 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]] PMID:36549457 13966748 APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of APEX2 mRNA PMID:35307453 13966938 SLIT3 slit guidance ligand 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLIT3 mRNA; deoxynivalenol results in decreased expression of SLIT3 protein PMID:38403181 13966938 SLIT3 slit guidance ligand 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of SLIT3 mRNA PMID:34933075 13966984 DNAJC17 DnaJ heat shock protein family (Hsp40) member C17 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DNAJC17 mRNA PMID:35307453 13967072 TRPV4 transient receptor potential cation channel subfamily V member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRPV4 mRNA PMID:35307453 13967299 CDH6 cadherin 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDH6 mRNA PMID:35307453 13967344 HAUS1 HAUS augmin like complex subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HAUS1 mRNA PMID:35307453 13967454 LRRC51 leucine rich repeat containing 51 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LRRC51 mRNA PMID:35307453 13967466 TMEM11 transmembrane protein 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM11 mRNA PMID:35307453 13967501 MARS1 methionyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MARS1 mRNA PMID:35307453 13967576 EPS8L2 EPS8 signaling adaptor L2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EPS8L2 mRNA PMID:35307453 13967629 ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ST8SIA1 mRNA PMID:35307453 13967731 CDON cell adhesion associated, oncogene regulated gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDON mRNA PMID:35307453 13967864 KLHDC3 kelch domain containing 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KLHDC3 mRNA PMID:35307453 13968041 ZNF436 zinc finger protein 436 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of ZNF436 mRNA PMID:34389318 13968062 RUFY1 RUN and FYVE domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RUFY1 mRNA PMID:35307453 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:10106 zearalenone affects expression EXP E RGD:6480464 20200519 CTD MESH:D015025 Zearalenone affects the expression of KEAP1 protein PMID:31760079 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20200519 CTD MESH:D015025 Zearalenone results in decreased expression of KEAP1 mRNA PMID:31760079 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in increased expression of KEAP1 mRNA] PMID:37999554 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:27744 glyphosate decreases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in decreased expression of KEAP1 mRNA PMID:35388968 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of KEAP1 mRNA PMID:37999554 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in increased expression of KEAP1 mRNA] PMID:37999554 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:4948 Evodiamine decreases expression EXP E RGD:6480464 20250114 CTD MESH:C049639 evodiamine results in decreased expression of KEAP1 protein PMID:39305878 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:4948 Evodiamine multiple interactions EXP E RGD:6480464 20250114 CTD MESH:C049639 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of KEAP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of KEAP1 protein] PMID:39305878 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:9381 T-2 toxin decreases expression EXP E RGD:6480464 20250114 CTD MESH:D013605 T-2 Toxin results in decreased expression of KEAP1 protein PMID:39305878 13968169 KEAP1 kelch like ECH associated protein 1 gene CHEBI:9381 T-2 toxin multiple interactions EXP E RGD:6480464 20250114 CTD MESH:D013605 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of KEAP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of KEAP1 protein] PMID:39305878 13968195 LOC100524373 platelet factor 4 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20250128 CTD MESH:D009151 Mustard Gas results in increased expression of PF4 mRNA PMID:18988085 13968196 CFH complement factor H gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFH mRNA PMID:35307453 13968197 MEIS2 Meis homeobox 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MEIS2 mRNA PMID:35307453 13968246 GOLIM4 golgi integral membrane protein 4 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of GOLIM4 mRNA; Resveratrol inhibits the reaction [Dietary Fats results in decreased expression of GOLIM4 mRNA] PMID:21852083 13968397 LGALS12 galectin 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LGALS12 mRNA PMID:35307453 13968458 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PMAIP1 mRNA PMID:35307453 13968458 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMAIP1 mRNA PMID:33891997 13968458 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMAIP1 mRNA PMID:33891997 13968509 PLBD2 phospholipase B domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLBD2 mRNA PMID:35307453 13968565 MTRF1L mitochondrial translation release factor 1 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MTRF1L mRNA PMID:35307453 13968859 TCERG1 transcription elongation regulator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TCERG1 mRNA PMID:35307453 13968905 ACSM3 acyl-CoA synthetase medium chain family member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACSM3 mRNA PMID:35307453 13968935 TRPT1 tRNA phosphotransferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRPT1 mRNA PMID:35307453 13968935 TRPT1 tRNA phosphotransferase 1 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of TRPT1 mRNA PMID:28069986 13969080 PDK1 pyruvate dehydrogenase kinase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PDK1 mRNA PMID:34416349 13969080 PDK1 pyruvate dehydrogenase kinase 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PDK1 mRNA PMID:34416349 13969080 PDK1 pyruvate dehydrogenase kinase 1 gene CHEBI:4357 deguelin multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C107676 deguelin results in increased expression of and results in increased phosphorylation of PDK1 protein PMID:37353039 13969165 ZNF428 zinc finger protein 428 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF428 mRNA; deoxynivalenol results in decreased expression of ZNF428 protein PMID:35307453|PMID:37257635 13969182 TICRR TOPBP1 interacting checkpoint and replication regulator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TICRR mRNA PMID:35307453 13969423 CYBA cytochrome b-245 alpha chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYBA mRNA PMID:35307453 13969502 PTGER3 prostaglandin E receptor 3 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in increased expression of PTGER3 mRNA PMID:33626375 13969559 PRLR prolactin receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRLR mRNA PMID:35307453 13969559 PRLR prolactin receptor gene CHEBI:16469 17beta-estradiol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased expression of PRLR protein alternative form PMID:18492821 13969760 TLCD1 TLC domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TLCD1 mRNA PMID:35307453 13970081 LRP2BP LRP2 binding protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LRP2BP mRNA PMID:35307453 13970153 DNAH11 dynein axonemal heavy chain 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAH11 mRNA PMID:35307453 13970309 SLC9A1 solute carrier family 9 member A1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC9A1 protein PMID:37257635 13970309 SLC9A1 solute carrier family 9 member A1 gene CHEBI:28179 benzamide decreases activity EXP E RGD:6480464 20191114 CTD MESH:C037689 benzamide analog results in decreased activity of SLC9A1 protein PMID:17724433 13970366 F3 coagulation factor III, tissue factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of F3 mRNA PMID:37257635 13970366 F3 coagulation factor III, tissue factor gene CHEBI:16469 17beta-estradiol affects expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol affects the expression of F3 mRNA; Estradiol affects the expression of F3 protein PMID:15964915 13970366 F3 coagulation factor III, tissue factor gene CHEBI:8772 raloxifene affects expression EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride affects the expression of F3 protein PMID:15964915 13970443 IKZF2 IKAROS family zinc finger 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IKZF2 mRNA PMID:35307453 13970601 LRRC42 leucine rich repeat containing 42 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LRRC42 mRNA PMID:35307453 13970636 RSL1D1 ribosomal L1 domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RSL1D1 mRNA PMID:35307453 13970706 SPEN spen family transcriptional repressor gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of SPEN mRNA PMID:21852083 13970725 E2F2 E2F transcription factor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of E2F2 mRNA PMID:35307453 13970741 STIP1 stress induced phosphoprotein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STIP1 mRNA PMID:35307453 13970893 MFSD2A MFSD2 lysolipid transporter A, lysophospholipid gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MFSD2A mRNA PMID:35307453 13970989 LRRC47 leucine rich repeat containing 47 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LRRC47 mRNA PMID:35307453 13971001 MCCC2 methylcrotonyl-CoA carboxylase subunit 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MCCC2 mRNA PMID:35307453 13971068 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SYNCRIP mRNA PMID:35307453 13971267 DYNC2H1 dynein cytoplasmic 2 heavy chain 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of DYNC2H1 mRNA PMID:21852083 13971844 CLSTN2 calsyntenin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CLSTN2 mRNA PMID:35307453 13971865 F2RL2 coagulation factor II thrombin receptor like 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of F2RL2 mRNA PMID:35307453 13971923 MRPS11 mitochondrial ribosomal protein S11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS11 mRNA PMID:35307453 13971939 FERMT1 FERM domain containing kindlin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FERMT1 mRNA PMID:35307453 13971977 COL4A1 collagen type IV alpha 1 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL4A1 mRNA PMID:35307453 13971977 COL4A1 collagen type IV alpha 1 chain gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COL4A1 mRNA PMID:34416349 13971977 COL4A1 collagen type IV alpha 1 chain gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COL4A1 mRNA PMID:34416349 13972038 TLR10 toll like receptor 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TLR10 mRNA PMID:35307453 13972086 LOC100519808 TRPM8 channel-associated factor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of TCAF1 mRNA; deoxynivalenol results in decreased expression of TCAF1 protein PMID:38403181 13972196 RBIS ribosomal biogenesis factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RBIS mRNA PMID:35307453 13972209 AGA aspartylglucosaminidase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AGA mRNA PMID:35307453 13972249 KCNIP1 potassium voltage-gated channel interacting protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KCNIP1 mRNA PMID:35307453 13972281 ATP2B4 ATPase plasma membrane Ca2+ transporting 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATP2B4 mRNA PMID:35307453 13972330 PARVB parvin beta gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in decreased expression of PARVB mRNA] PMID:21852083 13972400 CHN1 chimerin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of CHN2 mRNA PMID:35307453 13972400 CHN1 chimerin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CHN1 mRNA PMID:35307453 13972605 CLCN5 chloride voltage-gated channel 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLCN5 mRNA PMID:35307453 13972635 TYRO3 TYRO3 protein tyrosine kinase gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of TYRO3 mRNA PMID:18988085 13972635 TYRO3 TYRO3 protein tyrosine kinase gene CHEBI:29224 dibromine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in decreased expression of TYRO3 mRNA PMID:18790026 13972663 SPINK4 serine peptidase inhibitor Kazal type 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPINK4 mRNA PMID:35307453 13972686 CRYL1 crystallin lambda 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CRYL1 mRNA PMID:35307453 13972842 GMDS GDP-mannose 4,6-dehydratase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GMDS mRNA PMID:35307453 13972880 AP1S2 adaptor related protein complex 1 subunit sigma 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AP1S2 mRNA PMID:35307453 13972954 PPIG peptidylprolyl isomerase G gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPIG mRNA PMID:35307453 13972997 PAX9 paired box 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PAX9 mRNA PMID:35307453 13973167 KIFC2 kinesin family member C2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIFC2 mRNA PMID:35307453 13973208 SCN4A sodium voltage-gated channel alpha subunit 4 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of SCN4A mRNA PMID:34933075 13973321 CCNYL1 cyclin Y like 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCNYL1 mRNA PMID:35307453 13973343 ADA2 adenosine deaminase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADA2 mRNA PMID:35307453 13973357 WNT10B Wnt family member 10B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in decreased expression of WNT10B protein PMID:37257635 13973683 AVPR1A vasopressin receptor 1A gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of AVPR1A mRNA PMID:34933075 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:10022 deoxynivalenol increases phosphorylation EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased phosphorylation of EIF2A protein PMID:37442268 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 GSK2656157 inhibits the reaction [deoxynivalenol results in increased phosphorylation of EIF2A protein]; Selenium analog inhibits the reaction [deoxynivalenol results in increased phosphorylation of EIF2A protein] PMID:37442268 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:131923 salubrinal increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C496827 salubrinal results in increased phosphorylation of EIF2A protein PMID:17464326 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:139047 GSK2656157 multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C000597302 GSK2656157 inhibits the reaction [deoxynivalenol results in increased phosphorylation of EIF2A protein] PMID:37442268 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:16170 mercury(0) increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased phosphorylation of EIF2A protein PMID:16759985 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:22977 cadmium atom increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased phosphorylation of EIF2A protein PMID:16759985 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2A mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2A protein PMID:33891997 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:25195 mercury atom increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased phosphorylation of EIF2A protein PMID:16759985 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased phosphorylation of EIF2A protein] PMID:37442268 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:31823 mercury dichloride increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased phosphorylation of EIF2A protein PMID:16759985 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:35456 cadmium dichloride increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased phosphorylation of EIF2A protein PMID:16759985|PMID:17464326 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2A mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2A protein PMID:33891997 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased phosphorylation of EIF2A protein] PMID:37442268 13973733 EIF2A eukaryotic translation initiation factor 2A gene CHEBI:50842 norflurazon increases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in increased phosphorylation of EIF2A protein PMID:38432436 13973857 EXTL1 exostosin like glycosyltransferase 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of EXTL1 mRNA PMID:34933075 13973872 RHEBL1 RHEB like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RHEBL1 mRNA PMID:35307453 13974012 SPTLC3 serine palmitoyltransferase long chain base subunit 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPTLC3 mRNA PMID:35307453 13974303 CYBRD1 cytochrome b reductase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYBRD1 mRNA PMID:35307453 13974332 HNF4A hepatocyte nuclear factor 4 alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HNF4A mRNA PMID:35307453 13974372 SGO1 shugoshin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SGO1 mRNA PMID:35307453 13974586 CNOT10 CCR4-NOT transcription complex subunit 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CNOT10 mRNA PMID:35307453 13974679 KDM5C lysine demethylase 5C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KDM5C mRNA PMID:35307453 13974679 KDM5C lysine demethylase 5C gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of KDM5C mRNA PMID:34389318 13974745 CCT8 chaperonin containing TCP1 subunit 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCT8 mRNA PMID:35307453 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of AKT1 mRNA; deoxynivalenol results in decreased expression of AKT1 protein PMID:16099139|PMID:32229166 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:10022 deoxynivalenol decreases phosphorylation EXP E RGD:6480464 20200714 CTD MESH:C007262 deoxynivalenol results in decreased phosphorylation of AKT1 protein PMID:32229166|PMID:37120089 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] PMID:37120089 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20200714 CTD MESH:D008070 [Flavones co-treated with Lipopolysaccharides] results in increased phosphorylation of AKT1 protein PMID:31669396 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:16469 17beta-estradiol increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased phosphorylation of AKT1 protein PMID:17348974 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] PMID:37120089 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AKT1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of AKT1 protein PMID:33493553 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:24043 flavones multiple interactions EXP E RGD:6480464 20200714 CTD MESH:D047309 [Flavones co-treated with Lipopolysaccharides] results in increased phosphorylation of AKT1 protein PMID:31669396 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:29678 sodium arsenite decreases expression EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in decreased expression of AKT1 protein PMID:12760830 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:29678 sodium arsenite increases degradation EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in increased degradation of AKT1 protein PMID:16239170 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C017947 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of AKT1 protein]; sodium arsenite results in decreased expression of and results in increased phosphorylation of AKT1 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] PMID:16239170 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:3093 bifenthrin affects phosphorylation EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin affects the phosphorylation of AKT1 protein PMID:33901951 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:31767 lead diacetate increases expression EXP E RGD:6480464 20191114 CTD MESH:C008261 lead acetate results in increased expression of AKT1 mRNA PMID:29273543 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:32234 titanium dioxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C009495 titanium dioxide results in increased phosphorylation of AKT1 protein PMID:23380242 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A decreases expression EXP E RGD:6480464 20230307 CTD MESH:C020806 tetrabromobisphenol A results in decreased expression of AKT1 mRNA; tetrabromobisphenol A results in decreased expression of AKT1 protein PMID:35665993 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:34440 4-nonylphenol affects phosphorylation EXP E RGD:6480464 20240604 CTD MESH:C041594 4-nonylphenol affects the phosphorylation of AKT1 protein PMID:38246476 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AKT1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of AKT1 protein PMID:33493553 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:35549 perfluorooctanoic acid decreases phosphorylation EXP E RGD:6480464 20240604 CTD MESH:C023036 perfluorooctanoic acid results in decreased phosphorylation of AKT1 protein PMID:38145882 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:39329 etoxazole affects phosphorylation EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole affects the phosphorylation of AKT1 protein PMID:31744678 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:39329 etoxazole multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C508136 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein] PMID:31744678 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:39483 sodium dichromate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C016104 sodium bichromate results in decreased expression of AKT1 protein PMID:12760830 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:4357 deguelin multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C107676 deguelin results in increased expression of and results in increased phosphorylation of AKT1 protein PMID:37353039 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:50091 S-nitrosoglutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D026422 AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] PMID:11514583 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:50842 norflurazon decreases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased phosphorylation of AKT1 protein PMID:38432436 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:52289 wortmannin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C009687 Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] PMID:16239170 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:65329 LY294002 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] PMID:16239170|PMID:31744678 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:75142 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP E RGD:6480464 20191114 CTD MESH:C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKT1 protein PMID:16239170 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:75142 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of AKT1 protein] PMID:16239170 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:7719 ochratoxin A decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased phosphorylation of AKT1 protein PMID:30287338 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:8772 raloxifene decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride results in decreased phosphorylation of AKT1 protein PMID:17348974 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C432165 pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of AKT1 protein] PMID:31744678 13974772 AKT1 AKT serine/threonine kinase 1 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C093642 SB 203580 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein] PMID:31744678 13974773 SLC2A13 solute carrier family 2 member 13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC2A13 mRNA PMID:35307453 13974834 PIGX phosphatidylinositol glycan anchor biosynthesis class X gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PIGX mRNA PMID:35307453 13974874 FAM81A family with sequence similarity 81 member A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM81A mRNA PMID:35307453 13974953 ZNF296 zinc finger protein 296 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF296 mRNA PMID:35307453 13975221 TMPRSS5 transmembrane serine protease 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMPRSS5 mRNA PMID:35307453 13975473 CYP2C49 cytochrome P450 2C49 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of CYP2C49 mRNA PMID:34389318 13975473 CYP2C49 cytochrome P450 2C49 gene CHEBI:2533 alachlor decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:C000188 CYP2C49 protein results in decreased susceptibility to alachlor PMID:16315095 13975473 CYP2C49 cytochrome P450 2C49 gene CHEBI:50842 norflurazon multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C008677 CYP2C49 protein results in increased metabolism of and results in decreased susceptibility to norflurazone PMID:16315095 13975473 CYP2C49 cytochrome P450 2C49 gene CHEBI:63956 isoxaben decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:C057467 CYP2C49 protein results in decreased susceptibility to isoxaben PMID:16315095 13975473 CYP2C49 cytochrome P450 2C49 gene CHEBI:81981 chlorotoluron decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:C007033 CYP2C49 protein results in decreased susceptibility to chlortoluron PMID:16315095 13975504 AQP11 aquaporin 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AQP11 mRNA PMID:35307453 13975510 MMP17 matrix metallopeptidase 17 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MMP17 mRNA PMID:35307453 13975525 BACE1 beta-secretase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BACE1 mRNA PMID:35307453 13975579 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PIK3CD mRNA PMID:35307453 13975755 FER1L5 fer-1 like family member 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FER1L5 mRNA PMID:35307453 13975819 TPGS2 tubulin polyglutamylase complex subunit 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TPGS2 mRNA PMID:35307453 13975856 WDR81 WD repeat domain 81 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WDR81 mRNA PMID:35307453 13975896 CDH2 cadherin 2 gene CHEBI:27915 melamine decreases expression EXP E RGD:6480464 20191114 CTD MESH:C011907 melamine results in decreased expression of CDH2 protein PMID:30055240 13975986 GFRA1 GDNF family receptor alpha 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GFRA1 mRNA PMID:35307453 13976016 RMND5A required for meiotic nuclear division 5 homolog A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RMND5A mRNA PMID:35307453 13976253 WBP1L WW domain binding protein 1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WBP1L mRNA PMID:35307453 13976401 THOC6 THO complex subunit 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of THOC6 mRNA PMID:35307453 13976475 P2RY2 purinergic receptor P2Y2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of P2RY2 mRNA PMID:35307453 13976493 CANT1 calcium activated nucleotidase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CANT1 mRNA PMID:35307453 13976603 FGG fibrinogen gamma chain gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of FGG mRNA PMID:34389318 13976645 CXCL12 C-X-C motif chemokine ligand 12 gene CHEBI:39329 etoxazole increases expression EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole results in increased expression of CXCL12 mRNA PMID:31744678 13976730 PARP8 poly(ADP-ribose) polymerase family member 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PARP8 mRNA PMID:35307453 13976806 SPN sialophorin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SPN mRNA PMID:35307453 13976834 EPYC epiphycan gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of EPYC mRNA PMID:34933075 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:17489 3',5'-cyclic AMP increases abundance EXP E RGD:6480464 20191114 CTD MESH:D000242 GNRH1 protein results in increased abundance of Cyclic AMP PMID:15833593 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:17489 3',5'-cyclic AMP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000242 [Cobalt binds to GNRH1 protein] which results in increased abundance of Cyclic AMP PMID:15833593 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:27638 cobalt atom affects binding EXP E RGD:6480464 20191114 CTD MESH:D003035 Cobalt binds to GNRH1 protein PMID:15833593 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:27638 cobalt atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003035 [Cobalt binds to GNRH1 protein] which results in increased abundance of Cyclic AMP; [Cobalt binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:15833593 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:28112 nickel atom affects binding EXP E RGD:6480464 20191114 CTD MESH:D009532 Nickel binds to GNRH1 protein PMID:16892001 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:28112 nickel atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009532 [Nickel binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:16892001 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:28694 copper atom affects binding EXP E RGD:6480464 20191114 CTD MESH:D003300 Copper binds to GNRH1 protein PMID:16892001 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:28694 copper atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003300 [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:16892001 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:30052 copper(0) affects binding EXP E RGD:6480464 20191114 CTD MESH:D003300 Copper binds to GNRH1 protein PMID:16892001 13976848 GNRH1 gonadotropin releasing hormone 1 gene CHEBI:30052 copper(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003300 [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein PMID:16892001 13976868 SCARF2 scavenger receptor class F member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCARF2 mRNA PMID:35307453 13976902 P2RX5 purinergic receptor P2X 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of P2RX5 mRNA PMID:35307453 13976992 CHL1 cell adhesion molecule L1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CHL1 mRNA PMID:35307453 13977176 GOLT1B golgi transport 1B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GOLT1B mRNA PMID:35307453 13977465 COLEC12 collectin subfamily member 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COLEC12 mRNA PMID:35307453 13977482 EGR2 early growth response 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EGR2 mRNA PMID:35307453 13977493 RHOU ras homolog family member U gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of RHOU mRNA PMID:21852083 13977508 MPV17L MPV17 mitochondrial inner membrane protein like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MPV17L mRNA PMID:35307453 13977616 ITM2A integral membrane protein 2A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITM2A mRNA PMID:35307453 13977844 CDRT4 CMT1A duplicated region transcript 4 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CDRT4 mRNA PMID:34933075 13977934 HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HSD17B6 mRNA PMID:35307453 13977947 FLRT3 fibronectin leucine rich transmembrane protein 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FLRT3 mRNA PMID:35307453 13977963 CABYR calcium binding tyrosine phosphorylation regulated gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of CABYR mRNA PMID:35307453 13978120 ARHGAP24 Rho GTPase activating protein 24 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARHGAP24 mRNA PMID:35307453 13978269 LDLRAP1 low density lipoprotein receptor adaptor protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of LDLRAP1 mRNA; deoxynivalenol results in decreased expression of LDLRAP1 protein PMID:38403181 13978286 MAOB monoamine oxidase B gene CHEBI:23924 enzyme inhibitor decreases activity EXP E RGD:6480464 20210608 CTD MESH:D004791 Enzyme Inhibitors results in decreased activity of MAOB protein PMID:33359020 13978286 MAOB monoamine oxidase B gene CHEBI:7930 Pargyline decreases activity EXP E RGD:6480464 20210608 CTD MESH:D010293 Pargyline analog results in decreased activity of MAOB protein PMID:33359020 13978286 MAOB monoamine oxidase B gene CHEBI:8354 pralidoxime decreases activity EXP E RGD:6480464 20191114 CTD MESH:C028797 pralidoxime results in decreased activity of MAOB protein PMID:21195145 13978286 MAOB monoamine oxidase B gene CHEBI:8863 Riluzole decreases activity EXP E RGD:6480464 20210608 CTD MESH:D019782 Riluzole analog results in decreased activity of MAOB protein PMID:33359020 13978320 ACO1 aconitase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACO1 mRNA PMID:35307453 13978320 ACO1 aconitase 1 gene CHEBI:34905 paraquat decreases activity EXP E RGD:6480464 20191114 CTD MESH:D010269 Paraquat results in decreased activity of ACO1 protein PMID:11814328 13978320 ACO1 aconitase 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of ACO1 mRNA PMID:17363680 13978391 HCAR2 hydroxycarboxylic acid receptor 2 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of HCAR2 mRNA PMID:35307453 13978522 EFHC1 EF-hand domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EFHC1 mRNA PMID:35307453 13978587 EIF3J eukaryotic translation initiation factor 3 subunit J gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF3J mRNA; deoxynivalenol results in increased expression of EIF3J protein PMID:35307453|PMID:38403181 13978692 HSD17B14 hydroxysteroid 17-beta dehydrogenase 14 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of HSD17B14 mRNA PMID:28069986 13978856 CPED1 cadherin like and PC-esterase domain containing 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CPED1 mRNA PMID:34933075 13979142 IST1 IST1 factor associated with ESCRT-III gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IST1 mRNA PMID:35307453 13979177 CDK18 cyclin dependent kinase 18 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDK18 mRNA PMID:35307453 13979233 MRPL41 mitochondrial ribosomal protein L41 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL41 mRNA PMID:35307453 13979359 ADGRF4 adhesion G protein-coupled receptor F4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADGRF4 mRNA PMID:35307453 13979422 MRPS30 mitochondrial ribosomal protein S30 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS30 mRNA PMID:35307453 13979489 HEXD hexosaminidase D gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HEXD mRNA PMID:35307453 13979537 CORO2A coronin 2A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CORO2A mRNA PMID:35307453 13979565 SGK2 serum/glucocorticoid regulated kinase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SGK2 mRNA PMID:35307453 13979565 SGK2 serum/glucocorticoid regulated kinase 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of SGK2 mRNA PMID:34933075 13979822 RBM14 RNA binding motif protein 14 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RBM14 mRNA PMID:35307453 13980010 GADD45B growth arrest and DNA damage inducible beta gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of GADD45B mRNA PMID:37706587 13980010 GADD45B growth arrest and DNA damage inducible beta gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of GADD45B mRNA] PMID:37706587 13980010 GADD45B growth arrest and DNA damage inducible beta gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of GADD45B mRNA] PMID:37706587 13980024 GNAI2 G protein subunit alpha i2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of GNAI2 mRNA PMID:25455459 13980048 SAMD15 sterile alpha motif domain containing 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SAMD15 mRNA PMID:35307453 13980136 NFYC nuclear transcription factor Y subunit gamma gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NFYC mRNA PMID:35307453 13980251 VNN1 vanin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VNN1 mRNA PMID:35307453 13980328 PPRC1 PPARG related coactivator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPRC1 mRNA PMID:35307453 13980328 PPRC1 PPARG related coactivator 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of PPRC1 mRNA PMID:27617619 13980370 PPCS phosphopantothenoylcysteine synthetase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPCS mRNA PMID:35307453 13980419 SH2D6 SH2 domain containing 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SH2D6 mRNA PMID:35307453 13980621 EIF4E eukaryotic translation initiation factor 4E gene CHEBI:10022 deoxynivalenol decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased phosphorylation of EIF4E protein PMID:16099139 13980621 EIF4E eukaryotic translation initiation factor 4E gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF4E mRNA; deoxynivalenol results in increased expression of EIF4E protein PMID:35307453|PMID:38403181 13980648 TTC12 tetratricopeptide repeat domain 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TTC12 mRNA PMID:35307453 13980875 IL7 interleukin 7 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL7 mRNA PMID:33592257 13980875 IL7 interleukin 7 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL7 mRNA PMID:33592257 13980897 CDCP2 CUB domain containing protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDCP2 mRNA PMID:35307453 13980907 MYOM2 myomesin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYOM2 mRNA PMID:35307453 13981040 CCNE1 cyclin E1 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of CCNE1 mRNA PMID:37706587 13981040 CCNE1 cyclin E1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CCNE1 mRNA] PMID:37706587 13981040 CCNE1 cyclin E1 gene CHEBI:3093 bifenthrin decreases expression EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin results in decreased expression of CCNE1 mRNA PMID:33901951 13981040 CCNE1 cyclin E1 gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CCNE1 mRNA] PMID:37706587 13981040 CCNE1 cyclin E1 gene CHEBI:39329 etoxazole decreases expression EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole results in decreased expression of CCNE1 mRNA PMID:31744678 13981040 CCNE1 cyclin E1 gene CHEBI:6078 ivermectin decreases expression EXP E RGD:6480464 20201103 CTD MESH:D007559 Ivermectin results in decreased expression of CCNE1 mRNA PMID:31400776 13981124 PEBP4 phosphatidylethanolamine binding protein 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PEBP4 mRNA PMID:35307453 13981669 DTX4 deltex E3 ubiquitin ligase 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DTX4 mRNA PMID:35307453 13981850 NEDD9 neural precursor cell expressed, developmentally down-regulated 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NEDD9 mRNA PMID:35307453 13981875 ACSL4 acyl-CoA synthetase long chain family member 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ACSL4 mRNA PMID:35307453 13982068 FANCB FA complementation group B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FANCB mRNA PMID:35307453 13982157 REXO2 RNA exonuclease 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of REXO2 mRNA PMID:35307453 13982306 TOB1 transducer of ERBB2, 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TOB1 mRNA PMID:35307453 13982454 RORC RAR related orphan receptor C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RORC mRNA PMID:35307453 13982502 HRH2 histamine receptor H2 gene CHEBI:18295 histamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006632 [Histamine affects the activity of HRH2 protein] which affects the secretion of Chlorides PMID:12665126 13982566 PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PIK3R6 mRNA PMID:35307453 13982668 BTBD2 BTB domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of BTBD2 mRNA; deoxynivalenol results in decreased expression of BTBD2 protein PMID:38403181 13982780 ECH1 enoyl-CoA hydratase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ECH1 mRNA PMID:35307453 13982814 IGSF9B immunoglobulin superfamily member 9B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IGSF9B mRNA PMID:35307453 13982814 IGSF9B immunoglobulin superfamily member 9B gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of IGSF9B mRNA PMID:34933075 13982910 SH3TC2 SH3 domain and tetratricopeptide repeats 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SH3TC2 mRNA PMID:35307453 13982940 PDLIM5 PDZ and LIM domain 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDLIM5 mRNA PMID:35307453 13983052 FAXDC2 fatty acid hydroxylase domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAXDC2 mRNA PMID:35307453 13983217 CFL1 cofilin 1 gene CHEBI:88522 Monobutylphthalate decreases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in decreased expression of CFL1 mRNA PMID:35839969 13983522 BTG2 BTG anti-proliferation factor 2 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of BTG2 mRNA PMID:34389318 13983696 ADARB1 adenosine deaminase RNA specific B1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADARB1 mRNA PMID:35307453 13983745 CDKL2 cyclin dependent kinase like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDKL2 mRNA PMID:35307453 13983784 TRPM4 transient receptor potential cation channel subfamily M member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRPM4 mRNA PMID:35307453 13983845 MS4A7 membrane spanning 4-domains A7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MS4A7 mRNA PMID:35307453 13983943 METTL27 methyltransferase like 27 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of METTL27 mRNA PMID:35307453 13984048 ARMC9 armadillo repeat containing 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ARMC9 mRNA PMID:35307453 13984340 TP53INP1 tumor protein p53 inducible nuclear protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TP53INP1 mRNA PMID:35307453 13984371 LTBP1 latent transforming growth factor beta binding protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of LTBP1 mRNA; deoxynivalenol results in decreased expression of LTBP1 protein PMID:38403181 13984414 STING1 stimulator of interferon response cGAMP interactor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STING1 mRNA PMID:35307453 13984451 RND2 Rho family GTPase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RND2 mRNA PMID:35307453 13984474 TGFBR2 transforming growth factor beta receptor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TGFBR2 mRNA PMID:35307453 13984474 TGFBR2 transforming growth factor beta receptor 2 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in increased expression of TGFBR2 mRNA PMID:33626375 13984496 FAM186B family with sequence similarity 186 member B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM186B mRNA PMID:35307453 13984535 FAM107B family with sequence similarity 107 member B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM107B mRNA PMID:35307453 13984625 PLIN2 perilipin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLIN2 mRNA PMID:35307453 13984625 PLIN2 perilipin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of PLIN2 mRNA; deoxynivalenol results in increased expression of PLIN2 protein PMID:38403181 13984625 PLIN2 perilipin 2 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D008550 Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 protein] PMID:31535366 13984625 PLIN2 perilipin 2 gene CHEBI:6651 malathion decreases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in decreased expression of PLIN2 mRNA; Malathion results in decreased expression of PLIN2 protein PMID:31535366 13984625 PLIN2 perilipin 2 gene CHEBI:6651 malathion multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D008294 Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 protein] PMID:31535366 13984694 ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of ADAMTS20 mRNA PMID:34933075 13984772 BPI bactericidal permeability increasing protein gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of BPI mRNA PMID:34389318 13985013 CTDSPL CTD small phosphatase like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTDSPL mRNA PMID:35307453 13985345 OSBPL9 oxysterol binding protein like 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of OSBPL9 mRNA PMID:35307453 13985465 ZFR zinc finger RNA binding protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZFR mRNA PMID:35307453 13985505 LOC100511937 phosphatidylinositol 3-kinase regulatory subunit gamma gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20210525 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of PIK3R3 mRNA PMID:21852083 13985558 SMIM24 small integral membrane protein 24 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SMIM24 mRNA PMID:35307453 13985595 TADA2A transcriptional adaptor 2A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TADA2A mRNA PMID:35307453 13985653 TRIM11 tripartite motif containing 11 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRIM11 mRNA PMID:35307453 13985704 SLA-DOB MHC class II, DO beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HLA-DOB mRNA PMID:35307453 13985852 CYP26A1 cytochrome P450 family 26 subfamily A member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP26A1 mRNA PMID:35307453 13985927 IZUMO4 IZUMO family member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IZUMO4 mRNA PMID:35307453 13985980 ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARAP3 mRNA PMID:35307453 13986036 ALDOA aldolase, fructose-bisphosphate A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ALDOA mRNA PMID:35307453 13986123 DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAJC27 mRNA PMID:35307453 13986205 ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENPP4 mRNA PMID:35307453 13986317 LIN7A lin-7 homolog A, crumbs cell polarity complex component gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LIN7A mRNA PMID:35307453 13986341 F2 coagulation factor II, thrombin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of F2 mRNA PMID:35307453 13986550 SYMPK symplekin scaffold protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SYMPK mRNA PMID:35307453 13986591 METTL5 methyltransferase 5, N6-adenosine gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of METTL5 mRNA PMID:35307453 13986774 EXOSC2 exosome component 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EXOSC2 mRNA PMID:35307453 13986926 SH2B2 SH2B adaptor protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SH2B2 mRNA PMID:35307453 13986982 IL20RA interleukin 20 receptor subunit alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL20RA mRNA PMID:35307453 13987059 CHST3 carbohydrate sulfotransferase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CHST3 mRNA PMID:35307453 13987258 MRM3 mitochondrial rRNA methyltransferase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRM3 mRNA PMID:35307453 13987295 TRIM29 tripartite motif containing 29 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRIM29 mRNA PMID:35307453 13987295 TRIM29 tripartite motif containing 29 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of TRIM29 mRNA PMID:34933075 13987331 SERTAD4 SERTA domain containing 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SERTAD4 mRNA PMID:35307453 13987386 TMEM131 transmembrane protein 131 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM131 mRNA PMID:35307453 13987476 COX11 cytochrome c oxidase copper chaperone COX11 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of COX11 mRNA PMID:21852083 13987522 CDC42EP5 CDC42 effector protein 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDC42EP5 mRNA PMID:35307453 13987553 ENPEP glutamyl aminopeptidase gene CHEBI:2624 amastatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C016977 amastatin inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame] PMID:8141778 13987553 ENPEP glutamyl aminopeptidase gene CHEBI:2877 aspartame increases hydrolysis EXP E RGD:6480464 20191114 CTD MESH:D001218 ENPEP protein results in increased hydrolysis of Aspartame PMID:8141778 13987553 ENPEP glutamyl aminopeptidase gene CHEBI:2877 aspartame multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001218 1,10-phenanthroline inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; amastatin inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] PMID:8141778 13987553 ENPEP glutamyl aminopeptidase gene CHEBI:3312 calcium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002122 Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] PMID:8141778 13987553 ENPEP glutamyl aminopeptidase gene CHEBI:44975 1,10-phenanthroline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025205 1,10-phenanthroline inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame] PMID:8141778 13987624 ARPP21 cAMP regulated phosphoprotein 21 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARPP21 mRNA PMID:35307453 13987624 ARPP21 cAMP regulated phosphoprotein 21 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of ARPP21 mRNA] PMID:21852083 13987681 CORO1B coronin 1B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CORO1B mRNA PMID:35307453 13987696 TIMM50 translocase of inner mitochondrial membrane 50 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TIMM50 mRNA PMID:35307453 13987740 ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of ADAMTS3 mRNA PMID:34933075 13987766 ZSCAN10 zinc finger and SCAN domain containing 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZSCAN10 mRNA PMID:35307453 13988066 ZNF618 zinc finger protein 618 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF618 mRNA PMID:35307453 13988091 CAPN1 calpain 1 gene CHEBI:15379 dioxygen increases activity EXP E RGD:6480464 20191114 CTD MESH:D010100 Oxygen deficiency results in increased activity of CAPN1 protein PMID:9728040 13988091 CAPN1 calpain 1 gene CHEBI:15379 dioxygen increases expression EXP E RGD:6480464 20191114 CTD MESH:D010100 Oxygen deficiency results in increased expression of CAPN1 mRNA PMID:9728040 13988091 CAPN1 calpain 1 gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of CAPN1 mRNA] PMID:9728040 13988091 CAPN1 calpain 1 gene CHEBI:16480 nitric oxide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009569 Nitric Oxide results in decreased expression of CAPN1 mRNA PMID:9728040 13988091 CAPN1 calpain 1 gene CHEBI:27666 actinomycin D multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003609 Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of CAPN1 mRNA] PMID:9728040 13988091 CAPN1 calpain 1 gene CHEBI:33101 nitrogen dioxide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009585 Nitrogen Dioxide results in decreased expression of CAPN1 mRNA PMID:9728040 13988138 PDGFRB platelet derived growth factor receptor beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PDGFRB mRNA; deoxynivalenol results in decreased expression of PDGFRB protein PMID:35307453|PMID:38403181 13988249 DUS3L dihydrouridine synthase 3 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DUS3L mRNA PMID:35307453 13988276 SYTL4 synaptotagmin like 4 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of SYTL4 mRNA PMID:21852083 13988324 EHD4 EH domain containing 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EHD4 mRNA PMID:35307453 13988496 ALDH1L1 aldehyde dehydrogenase 1 family member L1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALDH1L1 mRNA PMID:35307453 13988665 SCNN1B sodium channel epithelial 1 subunit beta gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCNN1B mRNA PMID:35307453 13988711 MT-CO3 mitochondrially encoded cytochrome c oxidase III gene CHEBI:6651 malathion affects expression EXP E RGD:6480464 20191114 CTD MESH:D008294 Malathion affects the expression of COX3 mRNA PMID:17454254 13988747 HPX hemopexin gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of HPX mRNA PMID:34389318 13988795 NUP88 nucleoporin 88 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NUP88 mRNA PMID:35307453 13988827 RNF214 ring finger protein 214 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RNF214 mRNA PMID:35307453 13988887 GLRX glutaredoxin gene CHEBI:22977 cadmium atom decreases activity EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in decreased activity of GLRX protein PMID:16785314 13988887 GLRX glutaredoxin gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 GLRX protein inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; IDH2 protein inhibits the reaction [Cadmium results in decreased activity of GLRX protein]; oxalomalic acid promotes the reaction [Cadmium results in decreased activity of GLRX protein] PMID:16785314 13988887 GLRX glutaredoxin gene CHEBI:30926 3-oxalomalic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C015407 oxalomalic acid promotes the reaction [Cadmium Chloride results in decreased activity of GLRX protein]; oxalomalic acid promotes the reaction [Cadmium results in decreased activity of GLRX protein] PMID:16785314 13988887 GLRX glutaredoxin gene CHEBI:35456 cadmium dichloride decreases activity EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in decreased activity of GLRX protein PMID:16785314 13988887 GLRX glutaredoxin gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 GLRX protein inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; IDH2 protein inhibits the reaction [Cadmium Chloride results in decreased activity of GLRX protein]; oxalomalic acid promotes the reaction [Cadmium Chloride results in decreased activity of GLRX protein] PMID:16785314 13989199 SYTL1 synaptotagmin like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SYTL1 mRNA PMID:35307453 13989249 GPR137 G protein-coupled receptor 137 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPR137 mRNA PMID:35307453 13989417 PPP2R5A protein phosphatase 2 regulatory subunit B'alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PPP2R5A mRNA PMID:35307453 13989529 MID1 midline 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MID1 mRNA PMID:35307453 13989570 IL11RA interleukin 11 receptor subunit alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL11RA mRNA PMID:35307453 13989755 TOMM6 translocase of outer mitochondrial membrane 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230411 CTD MESH:C007262 deoxynivalenol results in increased expression of TOMM6 mRNA PMID:35307453 13989759 MUC13 mucin 13, cell surface associated gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MUC13 mRNA PMID:35307453 13989774 CRIM1 cysteine rich transmembrane BMP regulator 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of CRIM1 mRNA; deoxynivalenol results in decreased expression of CRIM1 protein PMID:38403181 13989802 PRKCD protein kinase C delta gene CHEBI:29678 sodium arsenite increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in increased phosphorylation of PRKCD protein PMID:15089098 13989802 PRKCD protein kinase C delta gene CHEBI:37537 phorbol 13-acetate 12-myristate increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein PMID:15089098 13989858 KPTN kaptin, actin binding protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KPTN mRNA PMID:35307453 13989957 IL22RA1 interleukin 22 receptor subunit alpha 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IL22RA1 mRNA PMID:35307453 13989957 IL22RA1 interleukin 22 receptor subunit alpha 1 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of IL22RA1 mRNA PMID:34933075 13990006 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of H6PD mRNA PMID:35307453 13990156 KTI12 KTI12 chromatin associated homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KTI12 mRNA PMID:35307453 13990166 ZNF862 zinc finger protein 862 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF862 mRNA PMID:35307453 13990200 ARF4 ADP ribosylation factor 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARF4 mRNA PMID:35307453 13990213 PTGR1 prostaglandin reductase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTGR1 mRNA PMID:35307453 13990380 ADAM12 ADAM metallopeptidase domain 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADAM12 mRNA PMID:35307453 13990728 ZNF385A zinc finger protein 385A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF385A mRNA PMID:35307453 13990779 SERPINB8 serpin family B member 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SERPINB8 mRNA PMID:35307453 13990817 FJX1 four-jointed box kinase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FJX1 mRNA PMID:35307453 13990851 EIF2B3 eukaryotic translation initiation factor 2B subunit gamma gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF2B3 mRNA PMID:35307453 13990873 PCTP phosphatidylcholine transfer protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCTP mRNA PMID:35307453 13990906 NAGS N-acetylglutamate synthase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NAGS mRNA PMID:35307453 13990963 NUP205 nucleoporin 205 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NUP205 mRNA PMID:35307453 13991106 TRPM5 transient receptor potential cation channel subfamily M member 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TRPM5 mRNA PMID:35307453 13991270 ACOT13 acyl-CoA thioesterase 13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACOT13 mRNA PMID:35307453 13991376 TOP2A DNA topoisomerase II alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TOP2A mRNA PMID:35307453 13991376 TOP2A DNA topoisomerase II alpha gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of TOP2A mRNA PMID:21852083 13991584 WFDC1 WAP four-disulfide core domain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WFDC1 mRNA PMID:35307453 13991584 WFDC1 WAP four-disulfide core domain 1 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of WFDC1 mRNA PMID:28069986 13991690 CIP2A cellular inhibitor of PP2A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CIP2A mRNA PMID:35307453 13991790 CACNA1E calcium voltage-gated channel subunit alpha1 E gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CACNA1E mRNA PMID:34933075 13991860 CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CROCC2 mRNA PMID:35307453 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GCLC mRNA PMID:35307453 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:10106 zearalenone affects expression EXP E RGD:6480464 20200519 CTD MESH:D015025 Zearalenone affects the expression of GCLC protein PMID:31760079 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20200519 CTD MESH:D015025 Zearalenone results in increased expression of GCLC mRNA PMID:31760079 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:16236 ethanol increases activity EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased activity of GCLC protein PMID:16792574 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of GCLC mRNA PMID:16792574 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:16236 ethanol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000431 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GCLC protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GCLC mRNA PMID:16792574 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLC mRNA] PMID:37999554 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GCLC mRNA PMID:33493553 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005492 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GCLC protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GCLC mRNA PMID:16792574 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:27584 aldosterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D000450 Aldosterone results in increased expression of GCLC protein PMID:24512358 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002945 Buthionine Sulfoximine inhibits the reaction [sulforaphane inhibits the reaction [Cisplatin results in decreased activity of GCLC protein]]; sulforaphane inhibits the reaction [Cisplatin results in decreased activity of GCLC protein] PMID:20732396 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:28714 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases activity EXP E RGD:6480464 20191114 CTD MESH:D019328 Buthionine Sulfoximine results in decreased activity of GCLC protein PMID:20732396 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:28714 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019328 Buthionine Sulfoximine inhibits the reaction [sulforaphane inhibits the reaction [Cisplatin results in decreased activity of GCLC protein]] PMID:20732396 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:30621 diarsenic trioxide increases activity EXP E RGD:6480464 20191114 CTD MESH:C006632 Arsenic Trioxide results in increased activity of GCLC protein PMID:18801422 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:30621 diarsenic trioxide increases expression EXP E RGD:6480464 20191114 CTD MESH:C006632 Arsenic Trioxide results in increased expression of GCLC mRNA PMID:18801422 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of GCLC mRNA PMID:37999554 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLC mRNA] PMID:37999554 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:34247 2,6-di-tert-butyl-4-methylphenol increases expression EXP E RGD:6480464 20191114 CTD MESH:D002084 Butylated Hydroxytoluene results in increased expression of GCLC mRNA PMID:9535746 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GCLC mRNA PMID:33493553 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:47807 sulforaphane increases activity EXP E RGD:6480464 20191114 CTD MESH:C016766 sulforaphane results in increased activity of GCLC protein PMID:20732396 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:47807 sulforaphane increases expression EXP E RGD:6480464 20191114 CTD MESH:C016766 sulforaphane results in increased expression of GCLC mRNA PMID:18547363 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:47807 sulforaphane multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C016766 Buthionine Sulfoximine inhibits the reaction [sulforaphane inhibits the reaction [Cisplatin results in decreased activity of GCLC protein]]; ochratoxin A inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]; sulforaphane inhibits the reaction [Cisplatin results in decreased activity of GCLC protein] PMID:18547363|PMID:20732396 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:49900 arsenous acid increases activity EXP E RGD:6480464 20191114 CTD MESH:C032793 Arsenic Trioxide results in increased activity of GCLC protein PMID:18801422 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:49900 arsenous acid increases expression EXP E RGD:6480464 20191114 CTD MESH:C032793 Arsenic Trioxide results in increased expression of GCLC mRNA PMID:18801422 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of GCLC mRNA PMID:18547363 13991983 GCLC glutamate-cysteine ligase catalytic subunit gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA] PMID:18547363 13992179 DDX47 DEAD-box helicase 47 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX47 mRNA PMID:35307453 13992195 TNNI1 troponin I1, slow skeletal type gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TNNI1 mRNA PMID:35307453 13992195 TNNI1 troponin I1, slow skeletal type gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of TNNI1 mRNA PMID:34933075 13992286 FMNL3 formin like 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FMNL3 mRNA PMID:35307453 13992400 EIF4G1 eukaryotic translation initiation factor 4 gamma 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF4G1 mRNA PMID:35307453 13992498 MORN4 MORN repeat containing 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MORN4 mRNA PMID:35307453 13992577 MIR744 microRNA mir-744 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20201006 CTD MESH:D015025 Zearalenone results in increased expression of MIR744 mRNA PMID:32439583 13992580 UPK3A uroplakin 3A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UPK3A mRNA PMID:35307453 13992710 GIMD1 GIMAP family P-loop NTPase domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GIMD1 mRNA PMID:35307453 13992830 SLC29A3 solute carrier family 29 member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC29A3 mRNA PMID:35307453 13992843 SLC37A4 solute carrier family 37 member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC37A4 mRNA PMID:35307453 13993177 SLC5A4 solute carrier family 5 member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC5A4 mRNA PMID:35307453 13993290 RAD51B RAD51 paralog B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAD51B mRNA PMID:35307453 13993421 SCNN1A sodium channel epithelial 1 subunit alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCNN1A mRNA PMID:35307453 13993588 SNX24 sorting nexin 24 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SNX24 mRNA PMID:35307453 13993651 TIMP2 TIMP metallopeptidase inhibitor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TIMP2 mRNA PMID:35307453 13993651 TIMP2 TIMP metallopeptidase inhibitor 2 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of TIMP2 mRNA PMID:28069986 13993651 TIMP2 TIMP metallopeptidase inhibitor 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 protein PMID:34416349 13993651 TIMP2 TIMP metallopeptidase inhibitor 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 protein PMID:34416349 13993651 TIMP2 TIMP metallopeptidase inhibitor 2 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased expression of TIMP2 mRNA PMID:14994279 13993672 HAVCR1 hepatitis A virus cellular receptor 1 gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20231003 CTD MESH:D005839 Gentamicins results in increased expression of HAVCR1 mRNA PMID:28372472 13993672 HAVCR1 hepatitis A virus cellular receptor 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C056933 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of HAVCR1 mRNA PMID:33905761 13993672 HAVCR1 hepatitis A virus cellular receptor 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C025589 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of HAVCR1 mRNA PMID:33905761 13993750 MTUS1 microtubule associated scaffold protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MTUS1 mRNA PMID:35307453 13993989 KAT8 lysine acetyltransferase 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KAT8 mRNA PMID:35307453 13994006 ZNF24 zinc finger protein 24 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of ZNF24 mRNA PMID:34389318 13994024 PCED1A PC-esterase domain containing 1A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCED1A mRNA PMID:35307453 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased expression of MYD88 mRNA; Lipopolysaccharides results in increased expression of MYD88 protein PMID:28528741 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008070 ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]; ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] PMID:28528741 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:18050 L-glutamine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D005973 Glutamine inhibits the reaction [bisphenol A results in increased expression of MYD88 mRNA] PMID:38154151 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of MYD88 mRNA PMID:38154151 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Glutamine inhibits the reaction [bisphenol A results in increased expression of MYD88 mRNA] PMID:38154151 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat results in increased expression of MYD88 protein PMID:34811946 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:34905 paraquat increases response to substance EXP E RGD:6480464 20230905 CTD MESH:D010269 MYD88 protein results in increased susceptibility to Paraquat PMID:34811946 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the activity of CAT protein]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 mRNA]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of MKI67 protein]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of TOMM20 protein]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L protein]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of PARP1 protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the phosphorylation of TP53 protein]]; [MYD88 protein affects the susceptibility to Paraquat] which affects the activity of CAT protein; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 mRNA; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 protein; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 protein; MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]; MYD88 protein affects the reaction [Paraquat affects the expression of OPA1 protein]; MYD88 protein affects the reaction [Paraquat results in decreased expression of BCL2 protein]; MYD88 protein affects the reaction [Paraquat results in decreased expression of BCL2L1 mRNA]; MYD88 protein affects the reaction [Paraquat results in decreased expression of MKI67 protein]; MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]; MYD88 protein affects the reaction [Paraquat results in decreased expression of TOMM20 protein]; MYD88 protein affects the reaction [Paraquat results in decreased phosphorylation of MTOR protein]; MYD88 protein affects the reaction [Paraquat results in increased activity of and results in increased cleavage of CASP3 protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of CASP3 mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of CDK2 protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of PARP1 protein]; Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]; Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]; Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]; Paraquat affects the reaction [MYD88 protein affects the phosphorylation of TP53 protein]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of OPA1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]] PMID:34811946 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the activity of CAT protein]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 mRNA]; 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of MKI67 protein]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of TOMM20 protein]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L protein]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]; 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of PARP1 protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the phosphorylation of TP53 protein]] PMID:34811946 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA]; ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] PMID:28528741 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:77732 cadmium nitrate affects expression EXP E RGD:6480464 20191114 CTD MESH:C035196 cadmium nitrate affects the expression of MYD88 mRNA PMID:29421334 13994040 MYD88 MYD88 innate immune signal transduction adaptor gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of OPA1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]] PMID:34811946 13994193 SIRPA signal regulatory protein alpha gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SIRPA mRNA PMID:35307453 13994193 SIRPA signal regulatory protein alpha gene CHEBI:16412 lipopolysaccharide affects expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides affects the expression of SIRPA mRNA PMID:21645290 13994299 RHOF ras homolog family member F, filopodia associated gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RHOF mRNA PMID:35307453 13994418 ZNF800 zinc finger protein 800 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF800 mRNA PMID:35307453 13994465 PRAP1 proline rich acidic protein 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of PRAP1 mRNA PMID:34389318 13994510 CLDN2 claudin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLDN2 mRNA PMID:35307453 13994648 CTNNB1 catenin beta 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTNNB1 protein PMID:30690062 13994648 CTNNB1 catenin beta 1 gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of CTNNB1 protein PMID:37659622 13994648 CTNNB1 catenin beta 1 gene CHEBI:17270 glycerol 2-phosphate multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C031463 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] PMID:30481989 13994648 CTNNB1 catenin beta 1 gene CHEBI:29073 L-ascorbic acid multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D001205 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] PMID:30481989 13994648 CTNNB1 catenin beta 1 gene CHEBI:3441 carvedilol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased expression of CTNNB1 mRNA PMID:16824628 13994648 CTNNB1 catenin beta 1 gene CHEBI:3441 carvedilol increases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in increased expression of CTNNB1 protein PMID:16824628 13994648 CTNNB1 catenin beta 1 gene CHEBI:34578 Bisphenol A diglycidyl ether multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C019273 bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] PMID:30481989 13994648 CTNNB1 catenin beta 1 gene CHEBI:41879 dexamethasone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D003907 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] PMID:30481989 13994648 CTNNB1 catenin beta 1 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C057693 Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] PMID:30481989 13994713 CLEC4F C-type lectin domain family 4 member F gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLEC4F mRNA PMID:35307453 13994723 GK glycerol kinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GK mRNA PMID:35307453 13994825 EIF2B2 eukaryotic translation initiation factor 2B subunit beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EIF2B2 mRNA PMID:35307453 13994938 NEURL1 neuralized E3 ubiquitin protein ligase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NEURL1 mRNA PMID:35307453 13994938 NEURL1 neuralized E3 ubiquitin protein ligase 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of NEURL1 mRNA PMID:34389318 13994981 DLC1 DLC1 Rho GTPase activating protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DLC1 mRNA PMID:35307453 13995064 SAL1 salivary lipocalin gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of SAL1 mRNA PMID:34389318 13995096 ATXN2 ataxin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ATXN2 mRNA PMID:35307453 13995670 GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GABRG3 mRNA PMID:35307453 13995684 ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ADAMTS6 mRNA PMID:35307453 13995712 ADGB androglobin gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of ADGB mRNA PMID:21852083 13995779 RNH1 ribonuclease/angiogenin inhibitor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RNH1 mRNA PMID:35307453 13995989 UQCRC2 ubiquinol-cytochrome c reductase core protein 2 gene CHEBI:50842 norflurazon decreases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased expression of UQCRC2 mRNA PMID:38432436 13996018 DNAH5 dynein axonemal heavy chain 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAH5 mRNA PMID:35307453 13996106 MKI67 marker of proliferation Ki-67 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MKI67 mRNA PMID:35307453 13996106 MKI67 marker of proliferation Ki-67 gene CHEBI:34905 paraquat decreases expression EXP E RGD:6480464 20230905 CTD MESH:D010269 Paraquat results in decreased expression of MKI67 protein PMID:34811946 13996106 MKI67 marker of proliferation Ki-67 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of MKI67 protein]]; MYD88 protein affects the reaction [Paraquat results in decreased expression of MKI67 protein] PMID:34811946 13996106 MKI67 marker of proliferation Ki-67 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of MKI67 protein]] PMID:34811946 13996301 ELL elongation factor for RNA polymerase II gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ELL mRNA PMID:35307453 13996321 DPM1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DPM1 mRNA PMID:35307453 13996417 NRL neural retina leucine zipper gene CHEBI:15367 all-trans-retinoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased expression of NRL protein PMID:16854989 13996475 UBASH3B ubiquitin associated and SH3 domain containing B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of UBASH3B mRNA PMID:35307453 13996506 EXOSC8 exosome component 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EXOSC8 mRNA PMID:35307453 13996581 ADGRL1 adhesion G protein-coupled receptor L1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADGRL1 mRNA PMID:35307453 13996716 NPHP1 nephrocystin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NPHP1 mRNA PMID:35307453 13996745 TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TANC2 mRNA PMID:35307453 13996871 RASGRP1 RAS guanyl releasing protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RASGRP1 mRNA PMID:35307453 13996871 RASGRP1 RAS guanyl releasing protein 1 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of RASGRP1 mRNA PMID:34933075 13996918 IQGAP1 IQ motif containing GTPase activating protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IQGAP1 mRNA PMID:35307453 13997029 COX4I1 cytochrome c oxidase subunit 4I1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COX4 mRNA PMID:34416349 13997029 COX4I1 cytochrome c oxidase subunit 4I1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COX4 mRNA PMID:34416349 13997397 KIRREL1 kirre like nephrin family adhesion molecule 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KIRREL1 mRNA PMID:35307453 13997432 ANXA1 annexin A1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of ANXA1 mRNA PMID:18988085 13997449 ADCY4 adenylate cyclase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADCY4 mRNA PMID:35307453 13997589 GEMIN5 gem nuclear organelle associated protein 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GEMIN5 mRNA PMID:35307453 13997696 EPCIP exosomal polycystin 1 interacting protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C007262 deoxynivalenol results in decreased expression of EPCIP mRNA PMID:35307453 13998194 TRPV2 transient receptor potential cation channel subfamily V member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRPV2 mRNA PMID:35307453 13998224 TMSB15B thymosin beta 15B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMSB15B mRNA PMID:35307453 13998257 BRIX1 biogenesis of ribosomes BRX1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BRIX1 mRNA PMID:35307453 13998315 RPF2 ribosome production factor 2 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RPF2 mRNA PMID:35307453 13998416 FUCA1 alpha-L-fucosidase 1 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of FUCA1 mRNA PMID:28069986 13998429 CALCOCO1 calcium binding and coiled-coil domain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CALCOCO1 mRNA PMID:35307453 13998429 CALCOCO1 calcium binding and coiled-coil domain 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CALCOCO1 mRNA PMID:34389318 13998465 MAPK6 mitogen-activated protein kinase 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MAPK6 mRNA PMID:35307453 13998465 MAPK6 mitogen-activated protein kinase 6 gene CHEBI:29678 sodium arsenite increases expression EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in increased expression of MAPK6 protein PMID:12760830 13998502 MPLKIP M-phase specific PLK1 interacting protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MPLKIP mRNA PMID:35307453 13998636 AATF apoptosis antagonizing transcription factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AATF mRNA PMID:35307453 13998732 CFAP99 cilia and flagella associated protein 99 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP99 mRNA PMID:35307453 13998772 LOC100627175 GRAM domain containing 2-like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GRAMD2A mRNA PMID:35307453 13998826 RUNDC3B RUN domain containing 3B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RUNDC3B mRNA PMID:35307453 13998900 DEGS2 delta 4-desaturase, sphingolipid 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DEGS2 mRNA PMID:35307453 13998900 DEGS2 delta 4-desaturase, sphingolipid 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of DEGS2 mRNA PMID:34933075 13998923 PRTG protogenin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRTG mRNA PMID:35307453 13998950 PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PIK3R5 mRNA PMID:35307453 13999079 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EIF4EBP2 mRNA PMID:35307453 13999103 GALNS galactosamine (N-acetyl)-6-sulfatase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GALNS mRNA PMID:35307453 13999214 FAM83A family with sequence similarity 83 member A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAM83A mRNA PMID:35307453 13999222 SIGIRR single Ig and TIR domain containing gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SIGIRR mRNA PMID:35307453 13999394 SLC2A7 solute carrier family 2 member 7 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of SLC2A7 mRNA PMID:34933075 13999452 ZBTB18 zinc finger and BTB domain containing 18 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZBTB18 mRNA PMID:35307453 13999522 CNTRL centriolin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CNTRL mRNA PMID:35307453 13999589 CTSZ cathepsin Z gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTSZ mRNA PMID:35307453 13999658 SNX16 sorting nexin 16 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of SNX16 mRNA; deoxynivalenol results in increased expression of SNX16 protein PMID:38403181 13999754 SMC1A structural maintenance of chromosomes 1A gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of SMC1A mRNA PMID:35839969 13999991 PAQR6 progestin and adipoQ receptor family member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PAQR6 mRNA PMID:35307453 14000091 ECE1 endothelin converting enzyme 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ECE1 mRNA PMID:35307453 14000113 RHOBTB1 Rho related BTB domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RHOBTB1 mRNA PMID:35307453 14000221 C9H11orf97 chromosome 9 C11orf97 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C9H11ORF97 mRNA PMID:35307453 14000240 CEP20 centrosomal protein 20 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CEP20 mRNA PMID:35307453 14000280 RAD51 RAD51 recombinase gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20201006 CTD MESH:C025589 ochratoxin A results in increased expression of RAD51 protein PMID:32454083 14000400 PLA2G1B phospholipase A2 group IB gene CHEBI:15365 acetylsalicylic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001241 Aspirin promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] PMID:10706128 14000400 PLA2G1B phospholipase A2 group IB gene CHEBI:15551 prostaglandin E2 increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:D015232 PLA2G1B protein results in increased chemical synthesis of Dinoprostone PMID:10706128 14000400 PLA2G1B phospholipase A2 group IB gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015237 [epostane co-treated with Dinoprost] results in increased expression of PLA2G1B mRNA PMID:20739670 14000400 PLA2G1B phospholipase A2 group IB gene CHEBI:6736 melittin increases activity EXP E RGD:6480464 20191114 CTD MESH:D008555 Melitten results in increased activity of PLA2G1B protein PMID:9092818 14000400 PLA2G1B phospholipase A2 group IB gene CHEBI:9352 sulindac multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013467 Sulindac promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] PMID:10706128 14000413 KIAA1671 KIAA1671 ortholog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KIAA1671 mRNA PMID:35307453 14000434 KCNQ5 potassium voltage-gated channel subfamily Q member 5 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KCNQ5 mRNA PMID:35307453 14000510 CAVIN2 caveolae associated protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CAVIN2 mRNA PMID:35307453 14000510 CAVIN2 caveolae associated protein 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CAVIN2 mRNA PMID:21852083 14000791 RYR1 ryanodine receptor 1 gene CHEBI:133663 thymol sulfate(1-) increases activity EXP E RGD:6480464 20191114 CTD MESH:D013943 Thymol results in increased activity of RYR1 protein PMID:17641978 14000791 RYR1 ryanodine receptor 1 gene CHEBI:22984 calcium atom increases activity EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in increased activity of RYR1 protein PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:22984 calcium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [Dantrolene inhibits the reaction [Calcium results in increased activity of RYR1 protein]] which results in decreased secretion of Calcium; Dantrolene inhibits the reaction [Calcium results in increased activity of RYR1 protein] PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:27607 thymol increases activity EXP E RGD:6480464 20191114 CTD MESH:D013943 Thymol results in increased activity of RYR1 protein PMID:17641978 14000791 RYR1 ryanodine receptor 1 gene CHEBI:27732 caffeine increases activity EXP E RGD:6480464 20191114 CTD MESH:D002110 Caffeine results in increased activity of RYR1 protein; Caffeine results in increased activity of RYR1 protein mutant form PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:27732 caffeine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002110 Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]]; Dantrolene inhibits the reaction [Caffeine results in increased activity of RYR1 protein mutant form]; Dantrolene inhibits the reaction [Caffeine results in increased activity of RYR1 protein] PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:29320 calcium(0) increases activity EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in increased activity of RYR1 protein PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:29320 calcium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [Dantrolene inhibits the reaction [Calcium results in increased activity of RYR1 protein]] which results in decreased secretion of Calcium; Dantrolene inhibits the reaction [Calcium results in increased activity of RYR1 protein] PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:33324 strontium atom increases activity EXP E RGD:6480464 20191114 CTD MESH:D013324 Strontium results in increased activity of RYR1 protein PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:33324 strontium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013324 Dantrolene inhibits the reaction [Strontium promotes the reaction [Ryanodine binds to RYR1 protein]]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein] PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:3440 carvacrol increases activity EXP E RGD:6480464 20191114 CTD MESH:C073316 carvacrol results in increased activity of RYR1 protein PMID:17641978 14000791 RYR1 ryanodine receptor 1 gene CHEBI:4317 dantrolene decreases activity EXP E RGD:6480464 20191114 CTD MESH:D003620 Dantrolene results in decreased activity of RYR1 protein PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:4317 dantrolene multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003620 5'-adenylyl (beta,gamma-methylene)diphosphonate affects the reaction [Dantrolene results in decreased activity of RYR1 protein]; [Dantrolene inhibits the reaction [Calcium results in increased activity of RYR1 protein]] which results in decreased secretion of Calcium; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]]; Dantrolene inhibits the reaction [Caffeine results in increased activity of RYR1 protein mutant form]; Dantrolene inhibits the reaction [Caffeine results in increased activity of RYR1 protein]; Dantrolene inhibits the reaction [Calcium results in increased activity of RYR1 protein]; Dantrolene inhibits the reaction [Ryanodine binds to RYR1 protein mutant form]; Dantrolene inhibits the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Strontium promotes the reaction [Ryanodine binds to RYR1 protein]] PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:8925 ryanodine affects binding EXP E RGD:6480464 20191114 CTD MESH:D012433 Ryanodine binds to RYR1 protein; Ryanodine binds to RYR1 protein mutant form PMID:11278295 14000791 RYR1 ryanodine receptor 1 gene CHEBI:8925 ryanodine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012433 5'-adenylyl (beta,gamma-methylene)diphosphonate affects the reaction [Ryanodine binds to RYR1 protein]; Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein mutant form]]; Dantrolene inhibits the reaction [Caffeine promotes the reaction [Ryanodine binds to RYR1 protein]]; Dantrolene inhibits the reaction [Ryanodine binds to RYR1 protein mutant form]; Dantrolene inhibits the reaction [Ryanodine binds to RYR1 protein]; Dantrolene inhibits the reaction [Strontium promotes the reaction [Ryanodine binds to RYR1 protein]]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein] PMID:11278295 14000900 ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ST8SIA4 mRNA PMID:35307453 14001031 LGMN legumain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LGMN mRNA PMID:35307453 14001064 STX1A syntaxin 1A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STX1A mRNA PMID:35307453 14001092 RPS6KA1 ribosomal protein S6 kinase A1 gene CHEBI:29678 sodium arsenite decreases expression EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in decreased expression of RPS6KA1 protein PMID:12760830 14001092 RPS6KA1 ribosomal protein S6 kinase A1 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D007559 pyrazolanthrone inhibits the reaction [Ivermectin results in decreased phosphorylation of RPS6KA1 protein]; U 0126 promotes the reaction [Ivermectin results in decreased phosphorylation of RPS6KA1 protein] PMID:31400776 14001092 RPS6KA1 ribosomal protein S6 kinase A1 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Ivermectin results in decreased phosphorylation of RPS6KA1 protein] PMID:31400776 14001172 HSPBP1 HSPA (Hsp70) binding protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HSPBP1 mRNA PMID:35307453 14001190 CTNNA1 catenin alpha 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of CTNNA1 mRNA PMID:21852083 14001297 DDIT4L DNA damage inducible transcript 4 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DDIT4L mRNA PMID:35307453 14001331 PDE10A phosphodiesterase 10A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PDE10A mRNA PMID:35307453 14001331 PDE10A phosphodiesterase 10A gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of PDE10A mRNA PMID:34933075 14001362 RPUSD2 RNA pseudouridine synthase domain containing 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RPUSD2 mRNA PMID:35307453 14001432 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of AASDHPPT mRNA; deoxynivalenol results in increased expression of AASDHPPT protein PMID:38403181 14001448 ASIC2 acid sensing ion channel subunit 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASIC2 mRNA PMID:35307453 14001508 AIF1 allograft inflammatory factor 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of AIF1 mRNA PMID:18988085 14001556 AKAP3 A-kinase anchoring protein 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AKAP3 mRNA PMID:35307453 14001667 KANSL1L KAT8 regulatory NSL complex subunit 1 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KANSL1L mRNA PMID:35307453 14001699 ATG9A autophagy related 9A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATG9A mRNA PMID:35307453 14001799 DBN1 drebrin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DBN1 mRNA PMID:35307453 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of STAT3 mRNA PMID:23326479 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:22977 cadmium atom increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased phosphorylation of STAT3 protein PMID:21783819 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of STAT3 protein] PMID:21783819 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:50131 5-aza-2'-deoxycytidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C014347 Decitabine inhibits the reaction [ochratoxin A results in increased phosphorylation of STAT3 protein] PMID:30923867 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:7719 ochratoxin A increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased phosphorylation of STAT3 protein PMID:30923867 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 Decitabine inhibits the reaction [ochratoxin A results in increased phosphorylation of STAT3 protein]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL3 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of OGG1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in increased expression of H2AX protein] PMID:30923867 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:77732 cadmium nitrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C035196 cadmium nitrate results in decreased expression of STAT3 mRNA PMID:29421334 14001826 STAT3 signal transducer and activator of transcription 3 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C093642 SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of STAT3 protein] PMID:21783819 14001950 TRMT10A tRNA methyltransferase 10A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRMT10A mRNA PMID:35307453 14002127 MAP7D2 MAP7 domain containing 2 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of MAP7D2 mRNA PMID:35839969 14002267 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDKAL1 mRNA PMID:35307453 14002267 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of CDKAL1 mRNA PMID:21852083 14002390 SLC5A2 solute carrier family 5 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC5A2 mRNA PMID:35307453 14002530 DARS1 aspartyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DARS1 mRNA PMID:35307453 14002530 DARS1 aspartyl-tRNA synthetase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of DARS1 mRNA PMID:21852083 14002575 DRC3 dynein regulatory complex subunit 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DRC3 mRNA PMID:35307453 14002749 SEC23A SEC23 homolog A, COPII coat complex component gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SEC23A mRNA PMID:35307453 14002811 WDR12 WD repeat domain 12 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of WDR12 mRNA PMID:35307453 14002832 RYR2 ryanodine receptor 2 gene CHEBI:8925 ryanodine affects binding EXP E RGD:6480464 20191114 CTD MESH:D012433 Ryanodine binds to RYR2 protein PMID:11278295 14002943 LAPTM5 lysosomal protein transmembrane 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LAPTM5 mRNA PMID:35307453 14003119 ABCC9 ATP binding cassette subfamily C member 9 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of ABCC9 mRNA PMID:34933075 14003443 PTMA prothymosin alpha gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of PTMA mRNA PMID:14994279 14003514 EFEMP2 EGF containing fibulin extracellular matrix protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EFEMP2 mRNA PMID:35307453 14003532 SLCO2B1 solute carrier organic anion transporter family member 2B1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLCO2B1 mRNA PMID:35307453 14003738 ENSA endosulfine alpha gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ENSA mRNA PMID:35307453 14003758 GTF2F1 general transcription factor IIF subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GTF2F1 mRNA PMID:35307453 14003889 PPP1R14B protein phosphatase 1 regulatory inhibitor subunit 14B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R14B mRNA PMID:35307453 14004011 PCP4L1 Purkinje cell protein 4 like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCP4L1 mRNA PMID:35307453 14004481 TMEM33 transmembrane protein 33 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of TMEM33 mRNA PMID:34389318 14004590 JADE2 jade family PHD finger 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of JADE2 mRNA PMID:35307453 14004590 JADE2 jade family PHD finger 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of JADE2 mRNA PMID:34933075 14004708 BBOF1 basal body orientation factor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BBOF1 mRNA PMID:35307453 14004824 PTEN phosphatase and tensin homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTEN mRNA PMID:35307453 14004824 PTEN phosphatase and tensin homolog gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20230307 CTD MESH:D008550 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein] PMID:35665993 14004824 PTEN phosphatase and tensin homolog gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A increases expression EXP E RGD:6480464 20230307 CTD MESH:C020806 tetrabromobisphenol A results in increased expression of PTEN mRNA; tetrabromobisphenol A results in increased expression of PTEN protein PMID:35665993 14004824 PTEN phosphatase and tensin homolog gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C020806 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein] PMID:35665993 14004824 PTEN phosphatase and tensin homolog gene CHEBI:34440 4-nonylphenol increases expression EXP E RGD:6480464 20240604 CTD MESH:C041594 4-nonylphenol results in increased expression of PTEN protein PMID:38246476 14004824 PTEN phosphatase and tensin homolog gene CHEBI:4357 deguelin multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C107676 deguelin results in increased expression of and results in increased phosphorylation of PTEN protein PMID:37353039 14004945 GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GALNT18 mRNA PMID:35307453 14004975 GJB5 gap junction protein beta 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GJB5 mRNA PMID:35307453 14004989 INHCA inhibitor of carbonic anhydrase gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of PICA mRNA PMID:18988085 14005014 SERPING1 serpin family G member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SERPING1 mRNA PMID:35307453 14005136 NEK2 NIMA related kinase 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of NEK2 mRNA PMID:21852083 14005153 COX17 cytochrome c oxidase copper chaperone COX17 gene CHEBI:23414 copper(II) sulfate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019327 Copper Sulfate results in decreased expression of COX17 mRNA PMID:22585802 14005235 MRPS18A mitochondrial ribosomal protein S18A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS18A mRNA PMID:35307453 14005476 KIT KIT proto-oncogene, receptor tyrosine kinase gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of KIT mRNA PMID:26386189 14005635 EFR3A EFR3 homolog A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EFR3A mRNA PMID:35307453 14005698 RAE1 ribonucleic acid export 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RAE1 mRNA PMID:35307453 14005993 TCEA2 transcription elongation factor A2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TCEA2 mRNA PMID:35307453 14006067 TTC1 tetratricopeptide repeat domain 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TTC1 mRNA PMID:35307453 14006545 VPS50 VPS50 subunit of EARP/GARPII complex gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VPS50 mRNA PMID:35307453 14006786 CALR3 calreticulin 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CALR3 mRNA PMID:35307453 14006804 IQCG IQ motif containing G gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IQCG mRNA PMID:35307453 14006822 TBCC tubulin folding cofactor C gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TBCC mRNA PMID:35307453 14006837 GAS2L1 growth arrest specific 2 like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GAS2L1 mRNA PMID:35307453 14006985 LIPE lipase E, hormone sensitive type gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LIPE mRNA PMID:35307453 14007033 LTV1 LTV1 ribosome biogenesis factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LTV1 mRNA PMID:35307453 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAPK1 protein modified form PMID:26988607 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:10022 deoxynivalenol increases activity EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased activity of MAPK1 protein PMID:19674540 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:10022 deoxynivalenol increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol analog results in increased phosphorylation of MAPK1 protein; deoxynivalenol results in increased phosphorylation of MAPK1 protein PMID:22859312 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:135697 sarpogrelate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C064294 sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein] PMID:11426759 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C028451 3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK1 protein PMID:20406653 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C028451 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of MAPK1 protein] PMID:20406653 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16240 hydrogen peroxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein PMID:11325585|PMID:21798251 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] PMID:21798251 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16412 lipopolysaccharide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased phosphorylation of MAPK1 protein PMID:28528741 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008070 ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] PMID:28528741 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of MAPK1 mRNA PMID:32423882 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:17688 (S)-nicotine decreases phosphorylation EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased phosphorylation of MAPK1 protein PMID:32423882 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of MAPK1 mRNA PMID:32423882 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:18723 nicotine decreases phosphorylation EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased phosphorylation of MAPK1 protein PMID:32423882 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:207229 dihydroartemisinin decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C039060 artenimol results in decreased phosphorylation of MAPK1 protein PMID:29309768 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein PMID:10356984 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:27915 melamine increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C011907 melamine results in increased phosphorylation of MAPK1 protein PMID:30055240 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:2825 aristolochic acid A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C000228 aristolochic acid I results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [aristolochic acid I results in increased phosphorylation of and results in increased activity of MAPK1 protein] PMID:21658425 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:28790 serotonin increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D012701 Serotonin results in increased phosphorylation of MAPK1 protein PMID:11426759 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:28790 serotonin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012701 sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein] PMID:11426759 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:3093 bifenthrin increases phosphorylation EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin results in increased phosphorylation of MAPK1 protein PMID:33901951 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:32234 titanium dioxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C009495 titanium dioxide results in increased phosphorylation of MAPK1 protein PMID:23380242 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C023035 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein PMID:20406653 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:37537 phorbol 13-acetate 12-myristate increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein PMID:11325585 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:38221 fumonisin B1 increases phosphorylation EXP E RGD:6480464 20200211 CTD MESH:C056933 fumonisin B1 results in increased phosphorylation of MAPK1 protein PMID:31557363 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:39329 etoxazole increases phosphorylation EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole results in increased phosphorylation of MAPK1 protein PMID:31744678 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:39329 etoxazole multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C508136 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein] PMID:31744678 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:48843 disodium selenite increases expression EXP E RGD:6480464 20191114 CTD MESH:D018038 Sodium Selenite results in increased expression of MAPK1 protein PMID:17342738 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:5078 flavonol increases expression EXP E RGD:6480464 20191114 CTD MESH:C041477 3-hydroxyflavone results in increased expression of MAPK1 protein PMID:21126572 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:50842 norflurazon decreases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased phosphorylation of MAPK1 protein PMID:38432436 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D007559 pyrazolanthrone inhibits the reaction [Ivermectin results in decreased phosphorylation of MAPK1 protein]; U 0126 promotes the reaction [Ivermectin results in decreased phosphorylation of MAPK1 protein] PMID:31400776 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:65329 LY294002 multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C085911 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein PMID:31744678 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:68889 hydroxytyrosol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C005975 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] PMID:21798251 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:7719 ochratoxin A increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased phosphorylation of MAPK1 protein PMID:28699257 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] PMID:28528741 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:8228 pioglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C060836 Pioglitazone promotes the reaction [Troglitazone results in increased phosphorylation of MAPK1 protein] PMID:17065204 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C432165 [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; pyrazolanthrone inhibits the reaction [Ivermectin results in decreased phosphorylation of MAPK1 protein] PMID:31400776|PMID:31744678 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20201103 CTD MESH:C093642 SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein] PMID:31744678 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:9753 troglitazone increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone results in increased phosphorylation of MAPK1 protein PMID:17065204 14007049 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 Pioglitazone promotes the reaction [Troglitazone results in increased phosphorylation of MAPK1 protein] PMID:17065204 14007236 ANXA8 annexin A8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in increased expression of ANXA8 mRNA PMID:35307453 14007236 ANXA8 annexin A8 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20250128 CTD MESH:D015025 Zearalenone results in increased expression of ANXA8 mRNA PMID:34933075 14007236 ANXA8 annexin A8 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20250128 CTD MESH:D000431 Ethanol results in increased expression of ANXA8 mRNA PMID:28069986 14007258 DTD2 D-aminoacyl-tRNA deacylase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DTD2 mRNA PMID:35307453 14007274 SPTBN5 spectrin beta, non-erythrocytic 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPTBN5 mRNA PMID:35307453 14007350 THBS1 thrombospondin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of THBS1 mRNA; deoxynivalenol results in increased expression of THBS1 protein PMID:35307453|PMID:37257635 14007350 THBS1 thrombospondin 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of THBS1 mRNA PMID:25455459 14007500 NHS NHS actin remodeling regulator gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NHS mRNA PMID:35307453 14007685 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene CHEBI:1296 20-hydroxycholesterol increases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C025813 CYP7A1 protein results in increased metabolism of 20-hydroxycholesterol PMID:10882719 14007685 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene CHEBI:17703 26-hydroxycholesterol increases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C076996 CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol PMID:10882719 14007685 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene CHEBI:29224 dibromine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in decreased expression of CYP7A1 mRNA PMID:21391292 14007685 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene CHEBI:34310 (24S)-24-hydroxycholesterol increases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C044563 CYP7A1 protein results in increased metabolism of 24-hydroxycholesterol PMID:11013305 14007685 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene CHEBI:42977 25-hydroxycholesterol increases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C007997 CYP7A1 protein results in increased metabolism of 25-hydroxycholesterol PMID:10882719 14007685 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene CHEBI:76591 (25R)-cholest-5-ene-3beta,26-diol increases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C076996 CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol PMID:10882719 14007710 ATP6V0C ATPase H+ transporting V0 subunit c gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATP6V0C mRNA PMID:35307453 14007717 STPG2 sperm tail PG-rich repeat containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STPG2 mRNA PMID:35307453 14007733 RBL2 RB transcriptional corepressor like 2 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of RBL2 mRNA PMID:34389318 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VCAM1 mRNA PMID:35307453 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl increases expression EXP E RGD:6480464 20191114 CTD MESH:C028451 3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein PMID:19608276|PMID:20406653 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:1367 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C028451 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA] PMID:19608276|PMID:20406653 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA] PMID:15051824|PMID:19608276 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:17351 linoleic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D019787 Linoleic Acid results in increased expression of VCAM1 mRNA PMID:15051824|PMID:18155686 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:17351 linoleic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019787 [Linoleic Acid co-treated with Polychlorinated Biphenyls] results in increased expression of VCAM1 protein; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA]; prolinedithiocarbamate inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA] PMID:15051824|PMID:18155686 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of VCAM1 mRNA PMID:18988085 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:27363 zinc atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015032 [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA]] PMID:15226458 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:27432 alpha-linolenic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017962 alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA]; alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 protein] PMID:18155686 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:2781 apocynin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C056165 acetovanillone inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:30185 zinc(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015032 [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA]] PMID:15226458 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:30187 aluminium oxide increases expression EXP E RGD:6480464 20191114 CTD MESH:D000537 Aluminum Oxide results in increased expression of VCAM1 mRNA; Aluminum Oxide results in increased expression of VCAM1 protein PMID:18456438 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:32234 titanium dioxide increases expression EXP E RGD:6480464 20191114 CTD MESH:C009495 titanium dioxide results in increased expression of VCAM1 mRNA; titanium dioxide results in increased expression of VCAM1 protein PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:32234 titanium dioxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C009495 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]; acetovanillone inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]; epigallocatechin gallate inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]; prolinedithiocarbamate inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]; pyrazolanthrone inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]; SB 203580 inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl increases expression EXP E RGD:6480464 20191114 CTD MESH:C023035 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein PMID:20406653|PMID:22521609|PMID:24709675 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C023035 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; NFE2L2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA] PMID:20406653|PMID:22521609|PMID:24709675 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:37537 phorbol 13-acetate 12-myristate increases expression EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein PMID:16797888 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C045651 epigallocatechin gallate results in decreased expression of VCAM1 mRNA PMID:22521609 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:4806 (-)-epigallocatechin 3-gallate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C045651 epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; epigallocatechin gallate inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; epigallocatechin gallate inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] PMID:22521609|PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:50992 1,3-thiazolidine-2,4-dione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C089946 [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA]] PMID:15226458 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:65329 LY294002 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:88217 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C044387 [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA] PMID:15226458 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C093642 SB 203580 inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA] PMID:23380242 14007778 VCAM1 vascular cell adhesion molecule 1 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020123 Sirolimus inhibits the reaction [Zymosan analog results in increased expression of VCAM1 protein] PMID:16797888 14007864 PTPN12 protein tyrosine phosphatase non-receptor type 12 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PTPN12 mRNA PMID:35307453 14007939 TEKT1 tektin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TEKT1 mRNA PMID:35307453 14007963 BEND6 BEN domain containing 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BEND6 mRNA PMID:35307453 14008028 CPA1 carboxypeptidase A1 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of CPA1 mRNA PMID:34933075 14008028 CPA1 carboxypeptidase A1 gene CHEBI:27363 zinc atom increases activity EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased activity of CPA1 protein PMID:17093223 14008028 CPA1 carboxypeptidase A1 gene CHEBI:30185 zinc(0) increases activity EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased activity of CPA1 protein PMID:17093223 14008028 CPA1 carboxypeptidase A1 gene CHEBI:36560 zinc oxide increases activity EXP E RGD:6480464 20191114 CTD MESH:D015034 Zinc Oxide results in increased activity of CPA1 protein PMID:17093223 14008134 PLXDC1 plexin domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLXDC1 mRNA; deoxynivalenol results in decreased expression of PLXDC1 protein PMID:38403181 14008134 PLXDC1 plexin domain containing 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of PLXDC1 mRNA PMID:34933075 14008284 ESR1 estrogen receptor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ESR1 mRNA PMID:35307453 14008284 ESR1 estrogen receptor 1 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of ESR1 mRNA PMID:22484360 14008284 ESR1 estrogen receptor 1 gene CHEBI:16469 17beta-estradiol affects expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol affects the expression of ESR1 protein PMID:15653758|PMID:16680078 14008284 ESR1 estrogen receptor 1 gene CHEBI:16469 17beta-estradiol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in decreased expression of ESR1 protein; Estradiol results in decreased expression of ESR1 protein alternative form PMID:16431846|PMID:17348974 14008284 ESR1 estrogen receptor 1 gene CHEBI:28088 genistein decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019833 Genistein results in decreased expression of ESR1 protein PMID:22443950 14008284 ESR1 estrogen receptor 1 gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013749 Tetrachlorodibenzodioxin results in decreased expression of ESR1 mRNA; Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein PMID:16431846 14008284 ESR1 estrogen receptor 1 gene CHEBI:28197 daidzein increases expression EXP E RGD:6480464 20191114 CTD MESH:C004742 daidzein results in increased expression of ESR1 mRNA PMID:19617652 14008284 ESR1 estrogen receptor 1 gene CHEBI:34372 4,4'-sulfonyldiphenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C543008 bisphenol S results in decreased expression of ESR1 mRNA PMID:28352085 14008284 ESR1 estrogen receptor 1 gene CHEBI:34372 4,4'-sulfonyldiphenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C543008 bisphenol S results in increased expression of ESR1 protein PMID:28352085 14008284 ESR1 estrogen receptor 1 gene CHEBI:41774 tamoxifen affects binding EXP E RGD:6480464 20191114 CTD MESH:D013629 Tamoxifen metabolite binds to ESR1 protein PMID:16790557 14008284 ESR1 estrogen receptor 1 gene CHEBI:81584 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP E RGD:6480464 20191114 CTD MESH:C511295 2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR1 protein PMID:24956591 14008284 ESR1 estrogen receptor 1 gene CHEBI:8772 raloxifene affects binding EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride metabolite binds to ESR1 protein PMID:16790557 14008284 ESR1 estrogen receptor 1 gene CHEBI:8772 raloxifene affects expression EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride affects the expression of ESR1 protein PMID:15653758|PMID:16680078 14008284 ESR1 estrogen receptor 1 gene CHEBI:8772 raloxifene decreases expression EXP E RGD:6480464 20191114 CTD MESH:D020849 Raloxifene Hydrochloride results in decreased expression of ESR1 protein alternative form PMID:17348974 14008386 DNALI1 dynein axonemal light intermediate chain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNALI1 mRNA PMID:35307453 14008478 KLHL14 kelch like family member 14 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KLHL14 mRNA PMID:35307453 14008531 MCCD1 mitochondrial coiled-coil domain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MCCD1 mRNA PMID:35307453 14008631 SCD5 stearoyl-CoA desaturase 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SCD5 mRNA PMID:35307453 14008700 JMJD8 jumonji domain containing 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of JMJD8 mRNA PMID:35307453 14008789 GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GALNT11 mRNA PMID:35307453 14008826 RAB6A RAB6A, member RAS oncogene family gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RAB6A mRNA PMID:35307453 14009021 SLC39A10 solute carrier family 39 member 10 gene CHEBI:27363 zinc atom decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in decreased expression of SLC39A10 mRNA PMID:16804107 14009021 SLC39A10 solute carrier family 39 member 10 gene CHEBI:27363 zinc atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased expression of SLC39A10 mRNA PMID:16804107 14009021 SLC39A10 solute carrier family 39 member 10 gene CHEBI:30185 zinc(0) decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in decreased expression of SLC39A10 mRNA PMID:16804107 14009021 SLC39A10 solute carrier family 39 member 10 gene CHEBI:30185 zinc(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased expression of SLC39A10 mRNA PMID:16804107 14009021 SLC39A10 solute carrier family 39 member 10 gene CHEBI:35176 zinc sulfate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019287 Zinc Sulfate results in decreased expression of SLC39A10 mRNA PMID:16804107 14009021 SLC39A10 solute carrier family 39 member 10 gene CHEBI:35176 zinc sulfate increases expression EXP E RGD:6480464 20191114 CTD MESH:D019287 Zinc Sulfate results in increased expression of SLC39A10 mRNA PMID:16804107 14009150 RASA1 RAS p21 protein activator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RASA1 mRNA PMID:35307453 14009190 CCDC103 coiled-coil domain containing 103 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC103 mRNA PMID:35307453 14009375 BNC1 basonuclin zinc finger protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BNC1 mRNA PMID:35307453 14009444 C2H11orf86 chromosome 2 C11orf86 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C2H11ORF86 mRNA PMID:35307453 14009460 RFT1 RFT1 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RFT1 mRNA PMID:35307453 14009541 RLBP1 retinaldehyde binding protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RLBP1 mRNA PMID:35307453 14009678 EMP3 epithelial membrane protein 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EMP3 mRNA PMID:35307453 14009735 ENKD1 enkurin domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENKD1 mRNA PMID:35307453 14009800 USP6NL USP6 N-terminal like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of USP6NL mRNA PMID:35307453 14010053 CFAP58 cilia and flagella associated protein 58 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CFAP58 mRNA PMID:35307453 14010075 AMH anti-Mullerian hormone gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AMH mRNA PMID:35307453 14010075 AMH anti-Mullerian hormone gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of AMH mRNA PMID:32423882 14010075 AMH anti-Mullerian hormone gene CHEBI:17688 (S)-nicotine decreases secretion EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased secretion of AMH protein PMID:32423882 14010075 AMH anti-Mullerian hormone gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of AMH mRNA PMID:32423882 14010075 AMH anti-Mullerian hormone gene CHEBI:18723 nicotine decreases secretion EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased secretion of AMH protein PMID:32423882 14010075 AMH anti-Mullerian hormone gene CHEBI:31767 lead diacetate decreases expression EXP E RGD:6480464 20191114 CTD MESH:C008261 lead acetate results in decreased expression of AMH mRNA PMID:29273543 14010075 AMH anti-Mullerian hormone gene CHEBI:31767 lead diacetate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C008261 lead acetate results in decreased expression of and results in decreased secretion of AMH protein PMID:29273543 14010100 CCDC74B coiled-coil domain containing 74B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC74B mRNA PMID:35307453 14010117 SLC2A11 solute carrier family 2 member 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC2A11 mRNA PMID:35307453 14010215 HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20210803 CTD MESH:D002994 Clofibrate results in increased expression of HMGCS2 mRNA PMID:17363680 14010293 CNPY3 canopy FGF signaling regulator 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CNPY3 mRNA PMID:35307453 14010317 HES4 hes family bHLH transcription factor 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HES4 mRNA PMID:35307453 14010412 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of MTHFD1 mRNA; deoxynivalenol results in decreased expression of MTHFD1 protein PMID:38403181 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of GSTA1 mRNA PMID:35307453 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20250128 CTD MESH:D015025 Zearalenone results in decreased expression of GSTA1 mRNA PMID:34933075 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20250128 CTD MESH:D000431 Ethanol results in increased expression of GSTA1 mRNA PMID:16792574 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:16236 ethanol multiple interactions EXP E RGD:6480464 20250128 CTD MESH:D000431 [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSTA1 mRNA PMID:16792574 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20250128 CTD MESH:D005978 [Glutathione co-treated with Paraquat] results in increased expression of GSTA2 mRNA; Glutathione inhibits the reaction [Paraquat results in decreased expression of GSTA1 mRNA] PMID:36615853 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:27470 folic acid increases expression EXP E RGD:6480464 20250128 CTD MESH:D005492 Folic Acid deficiency results in increased expression of GSTA1 mRNA PMID:16792574 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20250128 CTD MESH:D005492 [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSTA1 mRNA PMID:16792574 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:34905 paraquat decreases expression EXP E RGD:6480464 20250128 CTD MESH:D010269 Paraquat results in decreased expression of GSTA1 mRNA PMID:36615853 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20250128 CTD MESH:D010269 [Glutathione co-treated with Paraquat] results in increased expression of GSTA2 mRNA; Glutathione inhibits the reaction [Paraquat results in decreased expression of GSTA1 mRNA] PMID:36615853 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:47807 sulforaphane increases expression EXP E RGD:6480464 20250128 CTD MESH:C016766 sulforaphane results in increased expression of GSTA1 mRNA PMID:18547363 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:47807 sulforaphane multiple interactions EXP E RGD:6480464 20250128 CTD MESH:C016766 ochratoxin A inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA] PMID:18547363 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:6651 malathion decreases expression EXP E RGD:6480464 20250128 CTD MESH:D008294 Malathion results in decreased expression of GSTA1 mRNA PMID:31535366 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20250128 CTD MESH:C025589 ochratoxin A results in decreased expression of GSTA1 mRNA PMID:18547363 14010548 LOC106504562 glutathione S-transferase alpha M14 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20250128 CTD MESH:C025589 ochratoxin A inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA] PMID:18547363 14010557 CDH23 cadherin related 23 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDH23 mRNA PMID:35307453 14010709 MYOF myoferlin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MYOF mRNA PMID:35307453 14010939 SDE2 SDE2 telomere maintenance homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SDE2 mRNA PMID:35307453 14011019 FMOD fibromodulin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FMOD mRNA PMID:35307453 14011036 METTL2A methyltransferase 2A, tRNA N3-cytidine gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of METTL2A mRNA PMID:35307453 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:17234 glucose increases transport EXP E RGD:6480464 20191114 CTD MESH:D005947 SLC2A1 protein results in increased transport of Glucose PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:17276 phloretin increases expression EXP E RGD:6480464 20191114 CTD MESH:D010693 Phloretin results in increased expression of SLC2A1 mRNA; Phloretin results in increased expression of SLC2A1 protein PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:17276 phloretin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010693 Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]; Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 protein] PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:17634 D-glucose increases transport EXP E RGD:6480464 20191114 CTD MESH:D005947 SLC2A1 protein results in increased transport of Glucose PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:2639 amiloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000584 Amiloride promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA] PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:27881 resveratrol increases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in increased expression of SLC2A1 protein PMID:21575630 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:4031 cyclosporin A decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D016572 SLC2A1 protein results in decreased susceptibility to Cyclosporine PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:4031 cyclosporin A increases expression EXP E RGD:6480464 20191114 CTD MESH:D016572 Cyclosporine results in increased expression of SLC2A1 mRNA; Cyclosporine results in increased expression of SLC2A1 protein PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:4031 cyclosporin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D016572 Amiloride promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]; Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA]; Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 protein] PMID:12081571 14011054 SLC2A1 solute carrier family 2 member 1 gene CHEBI:42758 aldehydo-D-glucose increases transport EXP E RGD:6480464 20191114 CTD MESH:D005947 SLC2A1 protein results in increased transport of Glucose PMID:12081571 14011139 ESPN espin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ESPN mRNA PMID:35307453 14011169 POLR3E RNA polymerase III subunit E gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of POLR3E mRNA PMID:35307453 14011210 NOL10 nucleolar protein 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NOL10 mRNA PMID:35307453 14011235 MNS1 meiosis specific nuclear structural 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MNS1 mRNA PMID:35307453 14011297 ZBTB46 zinc finger and BTB domain containing 46 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZBTB46 mRNA PMID:35307453 14011312 C6H1orf210 chromosome 6 C1orf210 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C6H1ORF210 mRNA PMID:35307453 14011486 KRI1 KRI1 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KRI1 mRNA PMID:35307453 14011578 PAK6 p21 (RAC1) activated kinase 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PAK6 mRNA PMID:35307453 14011578 PAK6 p21 (RAC1) activated kinase 6 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of PAK6 mRNA PMID:34933075 14011620 DNAI4 dynein axonemal intermediate chain 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAI4 mRNA PMID:35307453 14011640 FREM1 FRAS1 related extracellular matrix 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FREM1 mRNA PMID:35307453 14011738 VIL1 villin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VIL1 mRNA PMID:35307453 14011785 CS citrate synthase gene CHEBI:8863 Riluzole decreases activity EXP E RGD:6480464 20210608 CTD MESH:D019782 Riluzole analog results in decreased activity of CS protein PMID:33359020 14011851 AMMECR1L AMMECR1 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AMMECR1L mRNA PMID:35307453 14012190 NAB2 NGFI-A binding protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NAB2 mRNA PMID:35307453 14012233 TYSND1 trypsin like peroxisomal matrix peptidase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TYSND1 mRNA; deoxynivalenol results in decreased expression of TYSND1 protein PMID:35307453|PMID:37257635 14012246 SMN1 survival of motor neuron 1, telomeric gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SMN1 mRNA PMID:35307453 14012266 DRC12 dynein regulatory complex subunit 12 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DRC12 mRNA PMID:35307453 14012390 FAM161A FAM161 centrosomal protein A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM161A mRNA PMID:35307453 14012509 PDE5A phosphodiesterase 5A gene CHEBI:16356 3',5'-cyclic GMP increases degradation EXP E RGD:6480464 20191114 CTD MESH:D006152 PDE5 protein results in increased degradation of Cyclic GMP PMID:18669600 14012552 RGS12 regulator of G protein signaling 12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RGS12 mRNA PMID:35307453 14012577 PLEKHG4 pleckstrin homology and RhoGEF domain containing G4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLEKHG4 mRNA PMID:35307453 14012750 MATN1 matrilin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MATN1 mRNA PMID:35307453 14012872 CXCL11 C-X-C motif chemokine ligand 11 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CXCL11 mRNA PMID:34389318 14012872 CXCL11 C-X-C motif chemokine ligand 11 gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of CXCL11 mRNA PMID:22497863 14012892 AQP3 aquaporin 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20210406 CTD MESH:C006780 bisphenol A results in decreased expression of AQP3 mRNA PMID:32710935 14012974 ZSWIM7 zinc finger SWIM-type containing 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZSWIM7 mRNA PMID:35307453 14013004 FAM3C FAM3 metabolism regulating signaling molecule C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM3C mRNA PMID:35307453 14013095 GAS1 growth arrest specific 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of GAS1 mRNA] PMID:21852083 14013219 CCL14 C-C motif chemokine ligand 14 gene CHEBI:3093 bifenthrin decreases expression EXP E RGD:6480464 20210706 CTD MESH:C099952 bifenthrin results in decreased expression of CCL14 mRNA PMID:33901951 14013226 USH1G USH1 protein network component sans gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of USH1G mRNA PMID:35307453 14013617 MGST1 microsomal glutathione S-transferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MGST1 mRNA PMID:35307453 14013677 CDC25B cell division cycle 25B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDC25B mRNA PMID:35307453 14013769 COL11A2 collagen type XI alpha 2 chain gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of COL11A2 mRNA PMID:35307453 14013864 HDAC1 histone deacetylase 1 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased expression of HDAC1 mRNA; ochratoxin A results in increased expression of HDAC1 protein PMID:29080797 14013864 HDAC1 histone deacetylase 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 Panobinostat inhibits the reaction [ochratoxin A results in increased expression of HDAC1 mRNA]; Panobinostat inhibits the reaction [ochratoxin A results in increased expression of HDAC1 protein] PMID:29080797 14013864 HDAC1 histone deacetylase 1 gene CHEBI:85990 panobinostat multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C496932 Panobinostat inhibits the reaction [ochratoxin A results in increased expression of HDAC1 mRNA]; Panobinostat inhibits the reaction [ochratoxin A results in increased expression of HDAC1 protein] PMID:29080797 14013963 TP53 tumor protein p53 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007262 [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA; Acetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]; deoxynivalenol results in decreased expression of and results in decreased phosphorylation of TP53 protein; fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA] PMID:29109043|PMID:38104654 14013963 TP53 tumor protein p53 gene CHEBI:10033 warfarin increases expression EXP E RGD:6480464 20191114 CTD MESH:D014859 Warfarin results in increased expression of TP53 mRNA PMID:29358327 14013963 TP53 tumor protein p53 gene CHEBI:10033 warfarin increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D014859 TP53 protein results in increased susceptibility to Warfarin PMID:29358327 14013963 TP53 tumor protein p53 gene CHEBI:10033 warfarin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014859 [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of CDKN1A protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of EP300 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of SNAI2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein]; SNAI2 protein promotes the reaction [TP53 protein results in increased susceptibility to Warfarin]; Warfarin promotes the reaction [TP53 protein binds to SNAI2 promoter]; Warfarin results in increased expression of and results in decreased acetylation of TP53 protein PMID:29358327 14013963 TP53 tumor protein p53 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of TP53 mRNA PMID:29109043 14013963 TP53 tumor protein p53 gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015025 Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]; Acetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]; fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA]; Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA] PMID:29109043 14013963 TP53 tumor protein p53 gene CHEBI:16796 melatonin decreases expression EXP E RGD:6480464 20201103 CTD MESH:D008550 Melatonin results in decreased expression of TP53 mRNA PMID:31535366 14013963 TP53 tumor protein p53 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D008550 Melatonin inhibits the reaction [Malathion results in increased expression of TP53 mRNA] PMID:31535366 14013963 TP53 tumor protein p53 gene CHEBI:17026 progesterone decreases secretion EXP E RGD:6480464 20191114 CTD MESH:D011374 TP53 protein results in decreased secretion of Progesterone PMID:22151798 14013963 TP53 tumor protein p53 gene CHEBI:17026 progesterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011374 [TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone PMID:22151798 14013963 TP53 tumor protein p53 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of TP53 protein PMID:9302645 14013963 TP53 tumor protein p53 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in increased expression of and results in increased acetylation of TP53 protein PMID:23065251 14013963 TP53 tumor protein p53 gene CHEBI:27899 cisplatin increases expression EXP E RGD:6480464 20191114 CTD MESH:D002945 Cisplatin results in increased expression of TP53 PMID:12712633|PMID:20603111 14013963 TP53 tumor protein p53 gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002945 mangostin inhibits the reaction [Cisplatin results in increased expression of TP53] PMID:20603111 14013963 TP53 tumor protein p53 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]; Acetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]] PMID:29109043 14013963 TP53 tumor protein p53 gene CHEBI:29678 sodium arsenite increases expression EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in increased expression of TP53 PMID:13129816 14013963 TP53 tumor protein p53 gene CHEBI:30621 diarsenic trioxide increases expression EXP E RGD:6480464 20191114 CTD MESH:C006632 Arsenic Trioxide results in increased expression of TP53 PMID:13129816 14013963 TP53 tumor protein p53 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of TP53 protein PMID:28819136 14013963 TP53 tumor protein p53 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the phosphorylation of TP53 protein]]; Paraquat affects the reaction [MYD88 protein affects the phosphorylation of TP53 protein] PMID:34811946 14013963 TP53 tumor protein p53 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20191114 CTD MESH:C056933 fumonisin B1 results in increased expression of TP53 mRNA PMID:29109043 14013963 TP53 tumor protein p53 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C056933 [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]; fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA]; Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA] PMID:29109043 14013963 TP53 tumor protein p53 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the phosphorylation of TP53 protein]] PMID:34811946 14013963 TP53 tumor protein p53 gene CHEBI:46195 paracetamol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000082 Acetaminophen results in decreased expression of TP53 protein PMID:16330492 14013963 TP53 tumor protein p53 gene CHEBI:49900 arsenous acid increases expression EXP E RGD:6480464 20191114 CTD MESH:C032793 Arsenic Trioxide results in increased expression of TP53 PMID:13129816 14013963 TP53 tumor protein p53 gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of TP53 mRNA PMID:31535366 14013963 TP53 tumor protein p53 gene CHEBI:6651 malathion multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D008294 Melatonin inhibits the reaction [Malathion results in increased expression of TP53 mRNA] PMID:31535366 14013963 TP53 tumor protein p53 gene CHEBI:67547 alpha-mangostin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C021053 mangostin inhibits the reaction [Cisplatin results in increased expression of TP53] PMID:20603111 14013963 TP53 tumor protein p53 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased expression of TP53 protein PMID:28710020|PMID:32454083 14013963 TP53 tumor protein p53 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 NFE2L2 protein affects the reaction [ochratoxin A results in increased expression of TP53 protein] PMID:28710020 14014130 CBR4 carbonyl reductase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CBR4 mRNA PMID:35307453 14014302 ABCB6 ATP binding cassette subfamily B member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCB6 mRNA PMID:35307453 14014459 SPRTN SprT-like N-terminal domain gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SPRTN mRNA PMID:35307453 14014475 MYLK myosin light chain kinase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MYLK mRNA PMID:35307453 14014475 MYLK myosin light chain kinase gene CHEBI:22984 calcium atom affects uptake EXP E RGD:6480464 20191114 CTD MESH:D002118 MYLK protein affects the uptake of Calcium PMID:9506478 14014475 MYLK myosin light chain kinase gene CHEBI:22984 calcium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [ML 7 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium; [ML 9 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium PMID:9506478 14014475 MYLK myosin light chain kinase gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of MYLK mRNA PMID:21852083 14014475 MYLK myosin light chain kinase gene CHEBI:29320 calcium(0) affects uptake EXP E RGD:6480464 20191114 CTD MESH:D002118 MYLK protein affects the uptake of Calcium PMID:9506478 14014475 MYLK myosin light chain kinase gene CHEBI:29320 calcium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [ML 7 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium; [ML 9 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium PMID:9506478 14014475 MYLK myosin light chain kinase gene CHEBI:78761 ML-7 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C070571 [ML 7 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium PMID:9506478 14014661 LRRC59 leucine rich repeat containing 59 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of LRRC59 mRNA PMID:35307453 14014689 REPS1 RALBP1 associated Eps domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of REPS1 mRNA PMID:35307453 14014924 DCUN1D1 defective in cullin neddylation 1 domain containing 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of DCUN1D1 mRNA PMID:34389318 14014973 MPP7 MAGUK p55 scaffold protein 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MPP7 mRNA PMID:35307453 14015111 ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of ADAMTS8 mRNA PMID:28069986 14015124 CLEC4G C-type lectin domain family 4 member G gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLEC4G mRNA PMID:35307453 14015124 CLEC4G C-type lectin domain family 4 member G gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CLEC4G mRNA PMID:34933075 14015196 PANK1 pantothenate kinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PANK1 mRNA PMID:35307453 14015249 RELL2 RELT like 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RELL2 mRNA PMID:35307453 14015280 TGFB3 transforming growth factor beta 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TGFB3 mRNA PMID:35307453 14015310 ESM1 endothelial cell specific molecule 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ESM1 mRNA PMID:35307453 14015674 GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of GALNT12 mRNA PMID:35307453 14015674 GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 gene CHEBI:10106 zearalenone affects expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone affects the expression of GALNT12 mRNA PMID:34933075 14015773 C6H19orf12 chromosome 6 C19orf12 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C6H19ORF12 mRNA PMID:35307453 14015817 ENO2 enolase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENO2 mRNA PMID:35307453 14015899 SF3A1 splicing factor 3a subunit 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SF3A1 mRNA PMID:35307453 14015922 SLC25A35 solute carrier family 25 member 35 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC25A35 mRNA PMID:35307453 14016043 CPN1 carboxypeptidase N subunit 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CPN1 mRNA PMID:35307453 14016244 NPR1 natriuretic peptide receptor 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NPR1 mRNA PMID:35307453 14016270 PLD1 phospholipase D1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLD1 mRNA PMID:35307453 14016425 NAGA alpha-N-acetylgalactosaminidase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NAGA mRNA; deoxynivalenol results in decreased expression of NAGA protein PMID:35307453|PMID:38403181 14016624 DLG4 discs large MAGUK scaffold protein 4 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of DLG4 mRNA PMID:34933075 14016674 TRMT61A tRNA methyltransferase 61A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRMT61A mRNA PMID:35307453 14016676 VWA1 von Willebrand factor A domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of VWA1 mRNA PMID:35307453 14016792 ALDOC aldolase, fructose-bisphosphate C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ALDOC mRNA PMID:35307453 14017018 FAM20A FAM20A golgi associated secretory pathway pseudokinase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAM20A mRNA PMID:35307453 14017175 RCAN1 regulator of calcineurin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RCAN1 mRNA PMID:35307453 14017175 RCAN1 regulator of calcineurin 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20200331 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of RCAN1 mRNA PMID:21852083 14017212 FCER1A Fc epsilon receptor Ia gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of FCER1A mRNA PMID:21852083 14017360 VGF VGF nerve growth factor inducible gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VGF mRNA PMID:35307453 14017390 GARS1 glycyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GARS1 mRNA PMID:35307453 14017493 MGAM2 maltase-glucoamylase 2 (putative) gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MGAM2 mRNA PMID:35307453 14017553 PSMD10 proteasome 26S subunit, non-ATPase 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMD10 mRNA PMID:35307453 14017567 NEIL1 nei like DNA glycosylase 1 gene CHEBI:50131 5-aza-2'-deoxycytidine increases expression EXP E RGD:6480464 20191114 CTD MESH:C014347 Decitabine results in increased expression of NEIL1 mRNA PMID:30923867 14017567 NEIL1 nei like DNA glycosylase 1 gene CHEBI:50131 5-aza-2'-deoxycytidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C014347 Decitabine inhibits the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA] PMID:30923867 14017567 NEIL1 nei like DNA glycosylase 1 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of NEIL1 mRNA PMID:30923867 14017567 NEIL1 nei like DNA glycosylase 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]; Decitabine inhibits the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA]; STAT3 protein affects the reaction [ochratoxin A results in decreased expression of NEIL1 mRNA] PMID:30923867 14017605 TMEM8B transmembrane protein 8B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM8B mRNA PMID:35307453 14017701 LGALS8 galectin 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LGALS8 mRNA PMID:35307453 14017802 CBL Cbl proto-oncogene gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CBL mRNA; deoxynivalenol results in increased expression of CBL protein PMID:35307453|PMID:38403181 14018019 ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of ANKS1A mRNA PMID:34389318 14018078 AARS2 alanyl-tRNA synthetase 2, mitochondrial gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AARS2 mRNA PMID:35307453 14018181 FAM221A family with sequence similarity 221 member A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FAM221A mRNA PMID:35307453 14018211 ITGAL integrin subunit alpha L gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ITGAL mRNA PMID:35307453 14018336 TPM1 tropomyosin 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of TPM1 mRNA; deoxynivalenol results in decreased expression of TPM1 protein PMID:38403181 14018443 SLC1A7 solute carrier family 1 member 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC1A7 mRNA PMID:35307453 14018514 TVP23A trans-golgi network vesicle protein 23 homolog A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TVP23A mRNA PMID:35307453 14018743 APITD1 apoptosis-inducing, TAF9-like domain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CENPS mRNA PMID:35307453 14018743 APITD1 apoptosis-inducing, TAF9-like domain 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CENPS mRNA PMID:35307453 14018791 PALM2AKAP2 PALM2-AKAP2 fusion gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PALM2AKAP2 mRNA PMID:35307453 14018791 PALM2AKAP2 PALM2-AKAP2 fusion gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of PALM2AKAP2 mRNA] PMID:21852083 14018806 TOM1L2 target of myb1 like 2 membrane trafficking protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TOM1L2 mRNA PMID:35307453 14018891 PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PREX1 mRNA PMID:35307453 14019358 TFRC transferrin receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TFRC mRNA PMID:35307453 14019445 ATG14 autophagy related 14 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of ATG14 mRNA PMID:35839969 14019459 PRKCB protein kinase C beta gene CHEBI:37537 phorbol 13-acetate 12-myristate decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein PMID:15089098 14019642 PSMD6 proteasome 26S subunit, non-ATPase 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PSMD6 mRNA PMID:35307453 14019821 STX1B syntaxin 1B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STX1B mRNA PMID:35307453 14019838 SLC27A2 solute carrier family 27 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC27A2 mRNA PMID:35307453 14019955 USP54 ubiquitin specific peptidase 54 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of USP54 mRNA PMID:35307453 14020178 CCN2 cellular communication network factor 2 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of CCN2 mRNA PMID:27617619 14020199 BLOC1S2 biogenesis of lysosomal organelles complex 1 subunit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BLOC1S2 mRNA PMID:35307453 14020259 MPI mannose phosphate isomerase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MPI mRNA PMID:35307453 14020433 CHP2 calcineurin like EF-hand protein 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CHP2 mRNA PMID:34933075 14020451 CCL5 C-C motif chemokine ligand 5 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of CCL5 mRNA PMID:18988085 14020555 SEC61G SEC61 translocon subunit gamma gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SEC61G mRNA PMID:35307453 14020766 WNT9B Wnt family member 9B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WNT9B mRNA PMID:35307453 14020890 PEG10 paternally expressed 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PEG10 mRNA PMID:35307453 14020915 VPS72 vacuolar protein sorting 72 homolog gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VPS72 mRNA PMID:35307453 14021082 NHERF2 NHERF family PDZ scaffold protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230207 CTD MESH:C007262 deoxynivalenol results in decreased expression of NHERF2 mRNA PMID:35307453 14021154 RFC1 replication factor C subunit 1 gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of RFC1 mRNA PMID:34389318 14021250 TMEM200C transmembrane protein 200C gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of TMEM200C mRNA PMID:34933075 14021257 PRSS22 serine protease 22 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRSS22 mRNA PMID:35307453 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:15553 prostaglandin F2alpha increases secretion EXP E RGD:6480464 20191114 CTD MESH:D015237 GHRL protein results in increased secretion of Dinoprost PMID:19528263 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015237 STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost] PMID:19528263 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:16581 pregnenolone decreases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D011284 GHRL protein results in decreased metabolism of Pregnenolone PMID:22341706 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:17026 progesterone decreases secretion EXP E RGD:6480464 20191114 CTD MESH:D011374 GHRL protein results in decreased secretion of Progesterone PMID:19528263 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:17026 progesterone increases secretion EXP E RGD:6480464 20191114 CTD MESH:D011374 GHRL protein results in increased secretion of Progesterone PMID:17904772 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:17026 progesterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011374 Aminoglutethimide promotes the reaction [GHRL protein results in decreased secretion of Progesterone]; GHRL protein results in decreased chemical synthesis of and results in decreased secretion of Progesterone; STAT1 protein inhibits the reaction [GHRL protein results in decreased secretion of Progesterone] PMID:19528263|PMID:22341706 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:2654 aminoglutethimide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000616 Aminoglutethimide promotes the reaction [GHRL protein results in decreased secretion of Progesterone] PMID:22341706 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:7872 oxytocin increases secretion EXP E RGD:6480464 20191114 CTD MESH:D010121 GHRL protein results in increased secretion of Oxytocin PMID:19528263 14021273 GHRL ghrelin and obestatin prepropeptide gene CHEBI:7872 oxytocin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010121 STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Oxytocin] PMID:19528263 14021347 EAF2 ELL associated factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of EAF2 mRNA PMID:35307453 14021365 OCLN occludin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of OCLN mRNA; deoxynivalenol results in decreased expression of OCLN protein PMID:25701311|PMID:33817499|PMID:35307453|PMID:35381244|PMID:36596350|PMID:37120089|PMID:37442268 14021365 OCLN occludin gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20210309 CTD MESH:C007262 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein]]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN protein]; MAP1LC3B protein affects the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN protein]]; Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein] PMID:32877744|PMID:35381244|PMID:37120089|PMID:37442268 14021365 OCLN occludin gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of OCLN protein PMID:37659622 14021365 OCLN occludin gene CHEBI:146195 3-acetyldeoxynivalenol multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C043247 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in decreased expression of OCLN protein] PMID:37659622 14021365 OCLN occludin gene CHEBI:16240 hydrogen peroxide decreases expression EXP E RGD:6480464 20240903 CTD MESH:D006861 Hydrogen Peroxide results in decreased expression of OCLN mRNA; Hydrogen Peroxide results in decreased expression of OCLN protein PMID:38438008 14021365 OCLN occludin gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240903 CTD MESH:D006861 SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN protein]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN protein] PMID:38438008 14021365 OCLN occludin gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20210309 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of OCLN mRNA; Lipopolysaccharides results in decreased expression of OCLN protein PMID:32877744|PMID:37271275 14021365 OCLN occludin gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20210309 CTD MESH:D008070 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN protein]]; [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN protein]; MAP1LC3B protein affects the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in decreased expression of OCLN protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA] PMID:32877744|PMID:37271275 14021365 OCLN occludin gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] PMID:37120089 14021365 OCLN occludin gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D005978 Glutathione inhibits the reaction [Paraquat results in decreased expression of OCLN protein] PMID:36615853 14021365 OCLN occludin gene CHEBI:17394 N(5)-ethyl-L-glutamine multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C026166 [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN protein]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA] PMID:37271275|PMID:38438008 14021365 OCLN occludin gene CHEBI:17688 (S)-nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of OCLN mRNA PMID:32423882 14021365 OCLN occludin gene CHEBI:18723 nicotine decreases expression EXP E RGD:6480464 20200915 CTD MESH:D009538 Nicotine results in decreased expression of OCLN mRNA PMID:32423882 14021365 OCLN occludin gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] PMID:37442268 14021365 OCLN occludin gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C059514 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of OCLN mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of OCLN protein] PMID:37955343 14021365 OCLN occludin gene CHEBI:27915 melamine decreases expression EXP E RGD:6480464 20191114 CTD MESH:C011907 melamine results in decreased expression of OCLN protein PMID:30055240 14021365 OCLN occludin gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C017947 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein] PMID:35381244 14021365 OCLN occludin gene CHEBI:29865 benzo[a]pyrene decreases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in decreased expression of OCLN protein PMID:36754226 14021365 OCLN occludin gene CHEBI:29865 benzo[a]pyrene multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D001564 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of OCLN protein] PMID:36754226 14021365 OCLN occludin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in decreased expression of OCLN protein PMID:37108405 14021365 OCLN occludin gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Sodium Selenite affects the reaction [bisphenol A results in decreased expression of OCLN protein] PMID:37108405 14021365 OCLN occludin gene CHEBI:34905 paraquat decreases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in decreased expression of OCLN protein PMID:36615853 14021365 OCLN occludin gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D010269 Glutathione inhibits the reaction [Paraquat results in decreased expression of OCLN protein] PMID:36615853 14021365 OCLN occludin gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] PMID:37442268 14021365 OCLN occludin gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20200211 CTD MESH:C056933 fumonisin B1 results in decreased expression of OCLN mRNA; fumonisin B1 results in decreased expression of OCLN protein PMID:31557363|PMID:37955343 14021365 OCLN occludin gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C056933 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of OCLN mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of OCLN protein] PMID:37955343 14021365 OCLN occludin gene CHEBI:41500 4-phenylbutyric acid multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C075773 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of OCLN protein] PMID:36754226 14021365 OCLN occludin gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D018038 Sodium Selenite affects the reaction [bisphenol A results in decreased expression of OCLN protein] PMID:37108405 14021365 OCLN occludin gene CHEBI:4948 Evodiamine multiple interactions EXP E RGD:6480464 20250114 CTD MESH:C049639 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN protein] PMID:39305878 14021365 OCLN occludin gene CHEBI:64163 diquat increases expression EXP E RGD:6480464 20191114 CTD MESH:D004178 Diquat results in increased expression of OCLN protein PMID:26338884 14021365 OCLN occludin gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C093642 [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN protein]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA] PMID:37271275|PMID:38438008 14021365 OCLN occludin gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D020123 Sirolimus inhibits the reaction [3-acetyldeoxynivalenol results in decreased expression of OCLN protein] PMID:37659622 14021365 OCLN occludin gene CHEBI:9381 T-2 toxin decreases expression EXP E RGD:6480464 20250114 CTD MESH:D013605 T-2 Toxin results in decreased expression of OCLN mRNA; T-2 Toxin results in decreased expression of OCLN protein PMID:39305878 14021365 OCLN occludin gene CHEBI:9381 T-2 toxin multiple interactions EXP E RGD:6480464 20250114 CTD MESH:D013605 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN protein] PMID:39305878 14021365 OCLN occludin gene CHEBI:9753 troglitazone increases expression EXP E RGD:6480464 20230502 CTD MESH:C057693 Troglitazone results in increased expression of OCLN mRNA PMID:36596350 14021468 RHBDL1 rhomboid like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RHBDL1 mRNA PMID:35307453 14021549 SOX6 SRY-box transcription factor 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SOX6 mRNA PMID:35307453 14021932 ZMYND10 zinc finger MYND-type containing 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZMYND10 mRNA PMID:35307453 14022065 ATP6V1G2 ATPase H+ transporting V1 subunit G2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ATP6V1G2 mRNA PMID:35307453 14022065 ATP6V1G2 ATPase H+ transporting V1 subunit G2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of ATP6V1G2 mRNA PMID:21852083 14022084 WDR64 WD repeat domain 64 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of WDR64 mRNA PMID:35307453 14022184 PRSS8 serine protease 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRSS8 mRNA PMID:35307453 14022255 SHISA8 shisa family member 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SHISA8 mRNA PMID:35307453 14022302 TMEM132C transmembrane protein 132C gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM132C mRNA PMID:35307453 14022507 C18H7orf57 chromosome 18 C7orf57 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230307 CTD MESH:C007262 deoxynivalenol results in decreased expression of C18H7ORF57 mRNA PMID:35307453 14022553 IFFO2 intermediate filament family orphan 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of IFFO2 mRNA PMID:35307453 14022569 TWF2 twinfilin actin binding protein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TWF2 mRNA PMID:35307453 14022642 CCDC146 coiled-coil domain containing 146 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC146 mRNA PMID:35307453 14022794 SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 gene CHEBI:10106 zearalenone affects expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone affects the expression of SPOCK1 mRNA PMID:34933075 14022817 AP1S3 adaptor related protein complex 1 subunit sigma 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AP1S3 mRNA PMID:35307453 14022833 YARS1 tyrosyl-tRNA synthetase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of YARS1 mRNA PMID:35307453 14022857 NRGN neurogranin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NRGN mRNA PMID:35307453 14022877 RASIP1 Ras interacting protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RASIP1 mRNA PMID:35307453 14022893 TNXB tenascin XB gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of TNXB mRNA PMID:18988085 14022993 PCK1 phosphoenolpyruvate carboxykinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCK1 mRNA PMID:35307453 14022993 PCK1 phosphoenolpyruvate carboxykinase 1 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of PCK1 mRNA; ochratoxin A results in decreased expression of PCK1 protein PMID:3753873 14023064 CAPS2 calcyphosine 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CAPS2 mRNA PMID:35307453 14023138 TLE2 TLE family member 2, transcriptional corepressor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TLE2 mRNA PMID:35307453 14023177 MAP3K7CL MAP3K7 C-terminal like gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of MAP3K7CL mRNA PMID:34933075 14023286 CRELD2 cysteine rich with EGF like domains 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CRELD2 mRNA PMID:35307453 14023348 DNAJC12 DnaJ heat shock protein family (Hsp40) member C12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAJC12 mRNA PMID:35307453 14023381 ACTB actin beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of ACTB mRNA PMID:26417708 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol results in increased expression of BAX protein PMID:38104654 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:146195 3-acetyldeoxynivalenol increases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in increased expression of BAX protein PMID:37659622 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:15428 glycine multiple interactions EXP E RGD:6480464 20240402 CTD MESH:D005998 Glycine inhibits the reaction [monobutyl phthalate results in increased expression of BAX mRNA] PMID:35839969 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:15866 2-deoxy-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003847 [Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] PMID:25087994 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of BAX mRNA PMID:37706587|PMID:38438008 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] PMID:37706587|PMID:38438008 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] PMID:25087994 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20200714 CTD MESH:D008070 Lipopolysaccharides results in increased expression of BAX protein PMID:31669396 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20200714 CTD MESH:D008070 Flavones inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein] PMID:31669396 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20230307 CTD MESH:D008550 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein] PMID:35665993 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:17394 N(5)-ethyl-L-glutamine multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C026166 theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] PMID:38438008 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20230606 CTD MESH:D001622 [Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA PMID:36584959 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20191114 CTD MESH:D005839 Gentamicins results in increased expression of BAX protein modified form PMID:16569831 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:207229 dihydroartemisinin increases expression EXP E RGD:6480464 20191114 CTD MESH:C039060 artenimol results in increased expression of BAX mRNA PMID:29309768 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in increased expression of BAX protein PMID:19135140 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of BAX protein]; Selenium inhibits the reaction [Cadmium results in increased expression of BAX protein] PMID:19135140|PMID:33493553 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:24043 flavones multiple interactions EXP E RGD:6480464 20200714 CTD MESH:D047309 Flavones inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein] PMID:31669396 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27363 zinc atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased expression of BAX protein PMID:11781163 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012643 Selenium inhibits the reaction [Cadmium results in increased expression of BAX protein] PMID:19135140 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:2762 antimycin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000968 [Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] PMID:25087994 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of BAX mRNA PMID:36584959 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27744 glyphosate multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C010974 [Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA PMID:36584959 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27881 resveratrol increases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in increased expression of BAX protein PMID:23065251 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C059514 Resveratrol inhibits the reaction [fumonisin B1 results in increased expression of BAX protein] PMID:37955343 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27899 cisplatin affects localization EXP E RGD:6480464 20191114 CTD MESH:D002945 Cisplatin affects the localization of BAX protein PMID:16316343 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002945 Bezafibrate inhibits the reaction [Cisplatin affects the localization of BAX protein] PMID:16316343 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of BAX protein] PMID:19135140|PMID:33905761 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:29865 benzo[a]pyrene increases expression EXP E RGD:6480464 20230704 CTD MESH:D001564 Benzo(a)pyrene results in increased expression of BAX protein PMID:36754226 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:30185 zinc(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased expression of BAX protein PMID:11781163 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in increased expression of BAX mRNA; bisphenol A results in increased expression of BAX protein PMID:37108405|PMID:38845341 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA] PMID:37108405|PMID:38845341 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A increases expression EXP E RGD:6480464 20230307 CTD MESH:C020806 tetrabromobisphenol A results in increased expression of BAX mRNA; tetrabromobisphenol A results in increased expression of BAX protein PMID:35665993 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C020806 Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein] PMID:35665993 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:33234 vitamin E multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D024502 Vitamin E inhibits the reaction [Cyclosporine affects the localization of BAX protein] PMID:19523970 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:34631 chlorpyrifos increases expression EXP E RGD:6480464 20231205 CTD MESH:D004390 Chlorpyrifos results in increased expression of BAX mRNA PMID:34399389|PMID:38565334 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:35176 zinc sulfate increases expression EXP E RGD:6480464 20191114 CTD MESH:D019287 Zinc Sulfate results in increased expression of BAX mRNA PMID:28803810 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:35176 zinc sulfate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019287 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BAX mRNA] PMID:28803810 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in increased expression of BAX protein PMID:26607349 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX protein; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein] PMID:26607349|PMID:33493553 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012643 Selenium inhibits the reaction [Cadmium results in increased expression of BAX protein] PMID:19135140 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of BAX mRNA PMID:17437637 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] PMID:37706587 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20211012 CTD MESH:C056933 fumonisin B1 results in increased expression of BAX mRNA; fumonisin B1 results in increased expression of BAX protein PMID:33905761|PMID:36397609|PMID:37955343 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C056933 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in increased expression of BAX protein] PMID:33905761|PMID:36397609|PMID:37955343 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025946 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BAX mRNA] PMID:28803810 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:39329 etoxazole increases expression EXP E RGD:6480464 20201103 CTD MESH:C508136 etoxazole results in increased expression of BAX protein PMID:31744678 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:4027 cyclophosphamide increases expression EXP E RGD:6480464 20240109 CTD MESH:D003520 Cyclophosphamide results in increased expression of BAX mRNA PMID:37980972 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:4027 cyclophosphamide multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D003520 Panobinostat inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA] PMID:37980972 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:4031 cyclosporin A affects localization EXP E RGD:6480464 20191114 CTD MESH:D016572 Cyclosporine affects the localization of BAX protein PMID:19523970 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:4031 cyclosporin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D016572 Vitamin E inhibits the reaction [Cyclosporine affects the localization of BAX protein] PMID:19523970 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:47612 bezafibrate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001629 Bezafibrate inhibits the reaction [Cisplatin affects the localization of BAX protein] PMID:16316343 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:48843 disodium selenite affects expression EXP E RGD:6480464 20191114 CTD MESH:D018038 Sodium Selenite affects the expression of BAX mRNA PMID:17342738 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:48843 disodium selenite multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D018038 Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAX protein] PMID:26607349|PMID:37108405 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of BAX mRNA PMID:31535366 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20211012 CTD MESH:C025589 ochratoxin A results in increased expression of BAX mRNA; ochratoxin A results in increased expression of BAX protein PMID:33905761|PMID:36397609 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C025589 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA; [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX protein]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA] PMID:33905761|PMID:36397609 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:80774 tauroursodeoxycholic acid multiple interactions EXP E RGD:6480464 20241105 CTD MESH:C031655 ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA] PMID:38845341 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:85990 panobinostat multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C496932 Panobinostat inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA] PMID:37980972 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of BAX mRNA PMID:35839969 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:88522 Monobutylphthalate multiple interactions EXP E RGD:6480464 20240402 CTD MESH:C028577 Glycine inhibits the reaction [monobutyl phthalate results in increased expression of BAX mRNA] PMID:35839969 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX mRNA] PMID:33905761 14023413 BAX BCL2 associated X, apoptosis regulator gene CHEBI:90705 SB 203580 multiple interactions EXP E RGD:6480464 20240903 CTD MESH:C093642 SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] PMID:38438008 14023426 PRM2 protamine 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of PRM2 mRNA PMID:25455459 14023531 ABCC3 ATP binding cassette subfamily C member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABCC3 mRNA; deoxynivalenol results in decreased expression of ABCC3 protein PMID:38403181 14023640 CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CACNG6 mRNA PMID:35307453 14023700 SLC22A5 solute carrier family 22 member 5 gene CHEBI:16347 (R)-carnitine increases uptake EXP E RGD:6480464 20191114 CTD MESH:D002331 SLC22A5 protein results in increased uptake of Carnitine PMID:16826461 14023700 SLC22A5 solute carrier family 22 member 5 gene CHEBI:165622 CAR(3:0(Me2)) decreases activity EXP E RGD:6480464 20201208 CTD MESH:C054040 pivaloylcarnitine results in decreased activity of SLC22A5 protein PMID:16826461 14023700 SLC22A5 solute carrier family 22 member 5 gene CHEBI:57589 O-acetyl-L-carnitine increases uptake EXP E RGD:6480464 20191114 CTD MESH:D000108 SLC22A5 protein results in increased uptake of Acetylcarnitine PMID:16826461 14023817 TMEM156 transmembrane protein 156 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TMEM156 mRNA PMID:35307453 14023869 CDYL chromodomain Y like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDYL mRNA PMID:35307453 14024130 TFR2 transferrin receptor 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TFR2 mRNA PMID:35307453 14024343 TRMT1L tRNA methyltransferase 1 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TRMT1L mRNA PMID:35307453 14024367 ADGRL2 adhesion G protein-coupled receptor L2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADGRL2 mRNA PMID:35307453 14024523 GLOD5 glyoxalase domain containing 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GLOD5 mRNA PMID:35307453 14024531 VRK2 VRK serine/threonine kinase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VRK2 mRNA PMID:35307453 14024559 GRB7 growth factor receptor bound protein 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GRB7 mRNA PMID:35307453 14024625 STOX1 storkhead box 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STOX1 mRNA PMID:35307453 14024638 METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of METTL3 mRNA PMID:35307453 14024689 DUSP1 dual specificity phosphatase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DUSP1 mRNA; deoxynivalenol results in increased expression of DUSP1 protein PMID:35307453|PMID:38403181 14024689 DUSP1 dual specificity phosphatase 1 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of DUSP1 mRNA PMID:34389318 14024689 DUSP1 dual specificity phosphatase 1 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20240604 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of DUSP1 mRNA PMID:37706587 14024689 DUSP1 dual specificity phosphatase 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D006861 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of DUSP1 mRNA] PMID:37706587 14024689 DUSP1 dual specificity phosphatase 1 gene CHEBI:37659 oleanolic acid multiple interactions EXP E RGD:6480464 20240604 CTD MESH:D009828 Oleanolic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of DUSP1 mRNA] PMID:37706587 14024785 LRRC56 leucine rich repeat containing 56 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LRRC56 mRNA PMID:35307453 14024815 DNAJC24 DnaJ heat shock protein family (Hsp40) member C24 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DNAJC24 mRNA PMID:35307453 14024943 FAIM2 Fas apoptotic inhibitory molecule 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAIM2 mRNA PMID:35307453 14024960 PDCD4 programmed cell death 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PDCD4 mRNA PMID:35307453 14025049 DOCK8 dedicator of cytokinesis 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DOCK8 mRNA PMID:35307453 14025119 CDCA8 cell division cycle associated 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDCA8 mRNA PMID:35307453 14025134 SLC39A2 solute carrier family 39 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC39A2 mRNA PMID:35307453 14025215 NEK11 NIMA related kinase 11 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NEK11 mRNA PMID:35307453 14025247 SLC1A1 solute carrier family 1 member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC1A1 mRNA PMID:35307453 14025247 SLC1A1 solute carrier family 1 member 1 gene CHEBI:33709 amino acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D000596 Amino Acids results in increased expression of SLC1A1 mRNA; Amino Acids results in increased expression of SLC1A1 protein PMID:26338884 14025247 SLC1A1 solute carrier family 1 member 1 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20210706 CTD MESH:C056933 fumonisin B1 results in decreased expression of SLC1A1 mRNA PMID:33443779 14025264 NR1D1 nuclear receptor subfamily 1 group D member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NR1D1 mRNA PMID:35307453 14025447 AHCTF1 AT-hook containing transcription factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AHCTF1 mRNA PMID:35307453 14025494 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 gene CHEBI:16412 lipopolysaccharide affects expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides affects the expression of SMARCA4 mRNA PMID:21645290 14025586 PPP2CB protein phosphatase 2 catalytic subunit beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP2CB mRNA PMID:35307453 14025684 NAV1 neuron navigator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NAV1 mRNA PMID:35307453 14025880 PLCH2 phospholipase C eta 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PLCH2 mRNA PMID:35307453 14025967 PCSK6 proprotein convertase subtilisin/kexin type 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PCSK6 mRNA PMID:35307453 14026012 MYO5B myosin VB gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYO5B mRNA PMID:35307453 14026215 CCAR1 cell division cycle and apoptosis regulator 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCAR1 mRNA PMID:35307453 14026473 RRAS2 RAS related 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RRAS2 mRNA PMID:35307453 14026645 KAT14 lysine acetyltransferase 14 gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of KAT14 mRNA PMID:35839969 14026698 MYL9 myosin light chain 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYL9 mRNA; deoxynivalenol results in decreased expression of MYL9 protein PMID:35307453|PMID:38403181 14026698 MYL9 myosin light chain 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230404 CTD MESH:C007262 deoxynivalenol results in increased expression of MYL12A mRNA PMID:35307453 14026698 MYL9 myosin light chain 9 gene CHEBI:15422 ATP decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D000255 Adenosine Triphosphate results in decreased phosphorylation of MYL9 protein PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:15422 ATP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000255 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein] PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:16335 adenosine decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D000241 Adenosine results in decreased phosphorylation of MYL9 protein PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:16335 adenosine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000241 8-phenyltheophylline inhibits the reaction [Adenosine results in decreased phosphorylation of MYL9 protein] PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:22984 calcium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [Calcium co-treated with 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid] results in decreased phosphorylation of MYL9 protein PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:29320 calcium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [Calcium co-treated with 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid] results in decreased phosphorylation of MYL9 protein PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:41791 calyculin a increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C059041 calyculin A results in increased phosphorylation of MYL9 protein PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:41791 calyculin a multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059041 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein] PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:60888 BAPTA multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025603 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; [Calcium co-treated with 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid] results in decreased phosphorylation of MYL9 protein PMID:10942722 14026698 MYL9 myosin light chain 9 gene CHEBI:78761 ML-7 decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:C070571 ML 7 results in decreased phosphorylation of MYL9 protein PMID:10942722 14026723 SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SUPT6H mRNA PMID:35307453 14026882 ZNF79 zinc finger protein 79 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of ZNF79 mRNA PMID:34389318 14027027 RPAP3 RNA polymerase II associated protein 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RPAP3 mRNA PMID:35307453 14027146 KIF20A kinesin family member 20A gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of KIF20A mRNA PMID:34389318 14027195 NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NAA15 mRNA PMID:35307453 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GAPDH mRNA PMID:35307453 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of GAPDH mRNA PMID:18988085 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012643 Selenium inhibits the reaction [Paraquat results in decreased activity of GAPDH protein] PMID:17055214 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:32139 sodium hydrogencarbonate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017693 [Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein PMID:26582256 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:3312 calcium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002122 [Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein PMID:26582256 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:34905 paraquat decreases activity EXP E RGD:6480464 20191114 CTD MESH:D010269 Paraquat results in decreased activity of GAPDH protein PMID:11814328|PMID:17055214 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010269 Selenium inhibits the reaction [Paraquat results in decreased activity of GAPDH protein] PMID:17055214 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012643 Selenium inhibits the reaction [Paraquat results in decreased activity of GAPDH protein] PMID:17055214 14027225 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene CHEBI:75249 potassium chromate decreases activity EXP E RGD:6480464 20191114 CTD MESH:C027373 potassium chromate(VI) results in decreased activity of GAPDH protein PMID:26582256 14027338 ARID3B AT-rich interaction domain 3B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ARID3B mRNA PMID:35307453 14027357 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NR1I2 mRNA PMID:35307453 14027538 ZC3H12D zinc finger CCCH-type containing 12D gene CHEBI:10022 deoxynivalenol affects expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol affects the expression of ZC3H12D mRNA PMID:35307453 14027555 EREG epiregulin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EREG mRNA PMID:35307453 14027591 VDAC2 voltage dependent anion channel 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of VDAC2 mRNA PMID:35307453 14027609 LAMA3 laminin subunit alpha 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of LAMA3 mRNA PMID:37257635 14027736 MT3 metallothionein 3 gene CHEBI:18421 superoxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013481 MT3 protein binds to and affects the metabolism of Superoxides PMID:12680700 14027736 MT3 metallothionein 3 gene CHEBI:25434 bis(2-chloroethyl) sulfide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in decreased expression of MT3 mRNA PMID:18988085 14027736 MT3 metallothionein 3 gene CHEBI:27363 zinc atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015032 MT3 protein binds to and affects the abundance of Zinc PMID:12405537 14027736 MT3 metallothionein 3 gene CHEBI:29191 hydroxyl multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017665 MT3 protein binds to and affects the metabolism of Hydroxyl Radical PMID:12680700 14027736 MT3 metallothionein 3 gene CHEBI:30185 zinc(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015032 MT3 protein binds to and affects the abundance of Zinc PMID:12405537 14027744 GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GPAT2 mRNA PMID:35307453 14027814 CBX6 chromobox 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CBX6 mRNA PMID:35307453 14027826 TMEM140 transmembrane protein 140 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM140 mRNA PMID:35307453 14027854 TNFSF9 TNF superfamily member 9 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TNFSF9 mRNA PMID:35307453 14027866 APOH apolipoprotein H gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of APOH mRNA PMID:34389318 14027935 BECN1 beclin 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of BECN1 mRNA; deoxynivalenol results in increased expression of BECN1 protein PMID:35381244|PMID:37120089 14027935 BECN1 beclin 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; Melatonin inhibits the reaction [deoxynivalenol results in increased expression of BECN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA] PMID:35381244|PMID:37120089 14027935 BECN1 beclin 1 gene CHEBI:146195 3-acetyldeoxynivalenol decreases expression EXP E RGD:6480464 20240109 CTD MESH:C043247 3-acetyldeoxynivalenol results in decreased expression of BECN1 protein PMID:37659622 14027935 BECN1 beclin 1 gene CHEBI:16796 melatonin increases expression EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin results in increased expression of BECN1 protein PMID:37120089 14027935 BECN1 beclin 1 gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D008550 Melatonin inhibits the reaction [deoxynivalenol results in increased expression of BECN1 protein] PMID:37120089 14027935 BECN1 beclin 1 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20240430 CTD MESH:C017947 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA] PMID:35381244 14027935 BECN1 beclin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of BECN1 mRNA PMID:28819136 14027935 BECN1 beclin 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA; Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]] PMID:34811946 14027935 BECN1 beclin 1 gene CHEBI:35176 zinc sulfate increases expression EXP E RGD:6480464 20191114 CTD MESH:D019287 Zinc Sulfate results in increased expression of BECN1 protein PMID:28803810 14027935 BECN1 beclin 1 gene CHEBI:35176 zinc sulfate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019287 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BECN1 protein] PMID:28803810 14027935 BECN1 beclin 1 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025946 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; 3-methyladenine affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BECN1 protein] PMID:28803810|PMID:34811946 14027935 BECN1 beclin 1 gene CHEBI:50842 norflurazon increases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in increased expression of BECN1 protein PMID:38432436 14027935 BECN1 beclin 1 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in increased expression of BECN1 protein PMID:30287338 14027935 BECN1 beclin 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C025589 BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of CASP3 protein]; BECN1 protein affects the reaction [ochratoxin A results in increased cleavage of PARP1 protein] PMID:30287338 14027935 BECN1 beclin 1 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]] PMID:34811946 14028047 H2BC5 H2B clustered histone 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of H2BC5 mRNA PMID:35307453 14028053 MRPL40 mitochondrial ribosomal protein L40 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL40 mRNA PMID:35307453 14028103 GLT6D1 glycosyltransferase 6 domain containing 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of GLT6D1 mRNA PMID:34933075 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:104872 rolipram decreases activity EXP E RGD:6480464 20191114 CTD MESH:D020889 Rolipram results in decreased activity of ADCYAP1 protein alternative form PMID:16847435 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 [Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein; Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein] PMID:28506824 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:16526 carbon dioxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002245 [Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein; Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein] PMID:28506824 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:17688 (S)-nicotine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009538 Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein] PMID:28506824 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:18723 nicotine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009538 Nicotine inhibits the reaction [[Carbon Dioxide co-treated with Oxygen deficiency] results in decreased expression of ADCYAP1 protein] PMID:28506824 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:31429 colforsin daropate hydrochloride decreases activity EXP E RGD:6480464 20191114 CTD MESH:D005576 Colforsin results in decreased activity of ADCYAP1 protein alternative form PMID:16847435 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of ADCYAP1 protein PMID:29569701 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:3374 capsaicin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002211 Capsaicin inhibits the reaction [ADCYAP1 protein alternative form results in decreased susceptibility to 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] PMID:14662737 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:90630 omega-conotoxin GVIA multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020866 omega-Conotoxin GVIA inhibits the reaction [ADCYAP1 protein alternative form results in decreased susceptibility to 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] PMID:14662737 14028124 ADCYAP1 adenylate cyclase activating polypeptide 1 gene CHEBI:91215 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C095284 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [ADCYAP1 protein alternative form results in decreased susceptibility to 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] PMID:14662737 14028181 PDE6C phosphodiesterase 6C gene CHEBI:16356 3',5'-cyclic GMP increases degradation EXP E RGD:6480464 20191114 CTD MESH:D006152 PDE6C protein results in increased degradation of Cyclic GMP PMID:18669600 14028346 PTGER4 prostaglandin E receptor 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTGER4 mRNA PMID:35307453 14028468 MCOLN3 mucolipin TRP cation channel 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MCOLN3 mRNA PMID:35307453 14028486 SLC36A2 solute carrier family 36 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC36A2 mRNA PMID:35307453 14028514 SLC50A1 solute carrier family 50 member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC50A1 mRNA PMID:35307453 14028643 AK1 adenylate kinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AK1 mRNA PMID:35307453 14028770 MRPL1 mitochondrial ribosomal protein L1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPL1 mRNA PMID:35307453 14028891 COL14A1 collagen type XIV alpha 1 chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of COL14A1 mRNA; deoxynivalenol results in decreased expression of COL14A1 protein PMID:35307453|PMID:38403181 14028891 COL14A1 collagen type XIV alpha 1 chain gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of COL14A1 mRNA PMID:21852083 14028969 FOXN1 forkhead box N1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FOXN1 mRNA PMID:35307453 14028999 CLXN calaxin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230404 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLXN mRNA PMID:35307453 14029082 BMI1 BMI1 proto-oncogene, polycomb ring finger gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in decreased expression of BMI1 protein PMID:30690062 14029165 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYP27A1 mRNA PMID:35307453 14029265 HCFC1 host cell factor C1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HCFC1 mRNA PMID:35307453 14029299 ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ST3GAL1 mRNA PMID:35307453 14029431 APLP2 amyloid beta precursor like protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of APLP2 mRNA PMID:35307453 14029458 LRRC25 leucine rich repeat containing 25 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LRRC25 mRNA PMID:35307453 14029705 MIOX myo-inositol oxygenase gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of MIOX mRNA PMID:28069986 14029807 MAFF MAF bZIP transcription factor F gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MAFF mRNA PMID:35307453 14030086 PHLDA1 pleckstrin homology like domain family A member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PHLDA1 mRNA PMID:35307453 14030120 FADS3 fatty acid desaturase 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FADS3 mRNA PMID:35307453 14030196 ZNF365 zinc finger protein 365 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF365 mRNA PMID:35307453 14030335 CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CASTOR1 mRNA PMID:35307453 14030368 DUSP14 dual specificity phosphatase 14 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DUSP14 mRNA PMID:35307453 14030381 HRH1 histamine receptor H1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HRH1 mRNA PMID:35307453 14030600 TAMALIN trafficking regulator and scaffold protein tamalin gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TAMALIN mRNA PMID:35307453 14030621 PIR pirin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PIR mRNA PMID:35307453 14030646 FAH fumarylacetoacetate hydrolase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FAH mRNA PMID:35307453 14030666 SLC18A3 solute carrier family 18 member A3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of SLC18A3 protein PMID:29558425|PMID:29577965 14030881 DCAF4 DDB1 and CUL4 associated factor 4 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DCAF4 mRNA PMID:35307453 14030945 PPP1R8 protein phosphatase 1 regulatory subunit 8 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R8 mRNA PMID:35307453 14031249 DRD3 dopamine receptor D3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DRD3 mRNA PMID:35307453 14031273 ARID1B AT-rich interaction domain 1B gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of ARID1B mRNA PMID:21852083 14031352 EPO erythropoietin gene CHEBI:27899 cisplatin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002945 [Cisplatin co-treated with EPO protein] results in increased cleavage of CASP3 protein PMID:21497595 14031361 STEAP1 STEAP family member 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of STEAP1 mRNA PMID:35307453 14031391 PTN pleiotrophin gene CHEBI:18376 dermatan sulfate affects binding EXP E RGD:6480464 20191114 CTD MESH:D003871 [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein PMID:14699094 14031391 PTN pleiotrophin gene CHEBI:37397 chondroitin sulfate affects binding EXP E RGD:6480464 20191114 CTD MESH:D002809 [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein PMID:14699094 14031420 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:6076 itraconazole multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017964 Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] PMID:21056966 14031420 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:64482 phosphatidylcholine increases export EXP E RGD:6480464 20191114 CTD MESH:D010713 ABCB4 protein results in increased export of Phosphatidylcholines PMID:21056966 14031420 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:64482 phosphatidylcholine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010713 Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] PMID:21056966 14031420 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:77733 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014700 Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] PMID:21056966 14031420 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:94366 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017964 Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] PMID:21056966 14031420 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:9948 verapamil multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014700 Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] PMID:21056966 14031561 TIMP1 TIMP metallopeptidase inhibitor 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TIMP1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TIMP1 protein PMID:34416349 14031561 TIMP1 TIMP metallopeptidase inhibitor 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of TIMP1 mRNA PMID:18988085 14031561 TIMP1 TIMP metallopeptidase inhibitor 1 gene CHEBI:29224 dibromine increases expression EXP E RGD:6480464 20191114 CTD MESH:D001966 Bromine results in increased expression of TIMP1 mRNA PMID:21391292 14031561 TIMP1 TIMP metallopeptidase inhibitor 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TIMP1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TIMP1 protein PMID:34416349 14031769 PPP1R10 protein phosphatase 1 regulatory subunit 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R10 mRNA PMID:35307453 14031887 EDN3 endothelin 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EDN3 mRNA PMID:35307453 14031977 RASEF RAS and EF-hand domain containing gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RASEF mRNA PMID:35307453 14032128 AP4S1 adaptor related protein complex 4 subunit sigma 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AP4S1 mRNA PMID:35307453 14032220 NMRK1 nicotinamide riboside kinase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NMRK1 mRNA PMID:35307453 14032275 CDH18 cadherin 18 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDH18 mRNA PMID:35307453 14032394 EFHD1 EF-hand domain family member D1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of EFHD1 mRNA PMID:35307453 14032407 ACADM acyl-CoA dehydrogenase medium chain gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACADM mRNA PMID:34416349 14032407 ACADM acyl-CoA dehydrogenase medium chain gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACADM mRNA PMID:34416349 14032423 RAB15 RAB15, member RAS oncogene family gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RAB15 mRNA PMID:35307453 14032449 H2AC19 H2A clustered histone 19 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of H2AC19 mRNA PMID:35307453 14032472 AQP6 aquaporin 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AQP6 mRNA PMID:35307453 14032485 DPP4 dipeptidyl peptidase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DPP4 mRNA PMID:35307453 14032537 CPT1A carnitine palmitoyltransferase 1A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CPT1A mRNA PMID:35307453 14032537 CPT1A carnitine palmitoyltransferase 1A gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of CPT1A mRNA PMID:34389318 14032537 CPT1A carnitine palmitoyltransferase 1A gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CPT1A mRNA PMID:34416349 14032537 CPT1A carnitine palmitoyltransferase 1A gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CPT1A mRNA PMID:34416349 14032537 CPT1A carnitine palmitoyltransferase 1A gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of CPT1A mRNA PMID:16896063|PMID:17363680 14032601 MFSD1 major facilitator superfamily domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MFSD1 mRNA PMID:35307453 14032625 ZNF462 zinc finger protein 462 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of ZNF462 mRNA PMID:21852083 14032859 PATL1 PAT1 homolog 1, processing body mRNA decay factor gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PATL1 mRNA PMID:35307453 14032893 GALE UDP-galactose-4-epimerase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GALE mRNA PMID:35307453 14032954 CAPN8 calpain 8 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CAPN8 mRNA PMID:35307453 14033043 SFTA2 surfactant associated 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SFTA2 mRNA PMID:35307453 14033404 MRPS31 mitochondrial ribosomal protein S31 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MRPS31 mRNA PMID:35307453 14033439 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GGA2 mRNA PMID:35307453 14033567 TMEM134 transmembrane protein 134 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM134 mRNA PMID:35307453 14033619 S100A12 S100 calcium binding protein A12 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S100A12 mRNA PMID:35307453 14033619 S100A12 S100 calcium binding protein A12 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of S100A12 mRNA PMID:34933075 14033642 CACNA1H calcium voltage-gated channel subunit alpha1 H gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CACNA1H mRNA PMID:34933075 14033741 DSG2 desmoglein 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DSG2 mRNA PMID:35307453 14033760 WDR43 WD repeat domain 43 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of WDR43 mRNA PMID:35307453 14033782 FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FCGR1A mRNA PMID:35307453 14033782 FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of FCGR1A mRNA PMID:34389318 14033949 LRRC75A leucine rich repeat containing 75A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LRRC75A mRNA PMID:35307453 14034078 CARS2 cysteinyl-tRNA synthetase 2, mitochondrial gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CARS2 mRNA PMID:35307453 14034180 ASB15 ankyrin repeat and SOCS box containing 15 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASB15 mRNA PMID:35307453 14034259 HPS3 HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HPS3 mRNA PMID:35307453 14034383 PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 gene CHEBI:22984 calcium atom decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in decreased phosphorylation of PDHA1 protein modified form PMID:16489745 14034383 PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 gene CHEBI:22984 calcium atom increases activity EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in increased activity of PDHA1 protein PMID:16489745 14034383 PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 gene CHEBI:29320 calcium(0) decreases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in decreased phosphorylation of PDHA1 protein modified form PMID:16489745 14034383 PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 gene CHEBI:29320 calcium(0) increases activity EXP E RGD:6480464 20191114 CTD MESH:D002118 Calcium results in increased activity of PDHA1 protein PMID:16489745 14034439 TLR3 toll like receptor 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of TLR3 mRNA; deoxynivalenol results in decreased expression of TLR3 protein PMID:38403181 14034439 TLR3 toll like receptor 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of TLR3 mRNA PMID:25455459 14034449 AZIN1 antizyme inhibitor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AZIN1 mRNA PMID:35307453 14034556 POU5F1 POU class 5 homeobox 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of POU5F1 mRNA; bisphenol A results in decreased expression of POU5F1 protein PMID:28819136 14034556 POU5F1 POU class 5 homeobox 1 gene CHEBI:4027 cyclophosphamide decreases expression EXP E RGD:6480464 20240109 CTD MESH:D003520 Cyclophosphamide results in decreased expression of POU5F1 mRNA PMID:37980972 14034556 POU5F1 POU class 5 homeobox 1 gene CHEBI:4027 cyclophosphamide multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D003520 Panobinostat inhibits the reaction [Cyclophosphamide results in decreased expression of POU5F1 mRNA] PMID:37980972 14034556 POU5F1 POU class 5 homeobox 1 gene CHEBI:85990 panobinostat multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C496932 Panobinostat inhibits the reaction [Cyclophosphamide results in decreased expression of POU5F1 mRNA] PMID:37980972 14034574 HIVEP1 HIVEP zinc finger 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HIVEP1 mRNA PMID:35307453 14034736 CD163 CD163 molecule gene CHEBI:34745 Estradiol 17beta-cyclopentylpropionate increases expression EXP E RGD:6480464 20191114 CTD MESH:C007630 estradiol 17 beta-cypionate results in increased expression of CD163 mRNA PMID:22497863 14034944 TK2 thymidine kinase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TK2 mRNA PMID:35307453 14035129 FOSL2 FOS like 2, AP-1 transcription factor subunit gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FOSL2 mRNA PMID:35307453 14035151 CCN1 cellular communication network factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CCN1 mRNA PMID:35307453 14035151 CCN1 cellular communication network factor 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of CCN1 mRNA PMID:27617619 14035380 RBM27 RNA binding motif protein 27 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RBM27 mRNA PMID:35307453 14035411 BST1 bone marrow stromal cell antigen 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BST1 mRNA PMID:35307453 14035505 CCDC88B coiled-coil domain containing 88B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC88B mRNA PMID:35307453 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SPP1 mRNA PMID:35307453 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:16469 17beta-estradiol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in decreased expression of SPP1 protein PMID:15713688 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:17270 glycerol 2-phosphate multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C031463 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] PMID:30481989 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of SPP1 mRNA PMID:18988085 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of SPP1 mRNA PMID:21852083 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:29073 L-ascorbic acid multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D001205 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] PMID:30481989 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:34578 Bisphenol A diglycidyl ether multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C019273 bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] PMID:30481989 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20211012 CTD MESH:C056933 fumonisin B1 results in increased expression of SPP1 mRNA PMID:33905761 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C056933 fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of SPP1 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of SPP1 mRNA] PMID:33905761 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:41879 dexamethasone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D003907 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; bisphenol A diglycidyl ether promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] PMID:30481989 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:50842 norflurazon decreases expression EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased expression of SPP1 mRNA PMID:38432436 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20211012 CTD MESH:C025589 ochratoxin A results in increased expression of SPP1 mRNA PMID:33905761 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C025589 fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of SPP1 mRNA]; ochratoxin A promotes the reaction [fumonisin B1 results in increased expression of SPP1 mRNA] PMID:33905761 14035682 SPP1 secreted phosphoprotein 1 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C057693 Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] PMID:30481989 14035738 CCDC198 coiled-coil domain containing 198 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CCDC198 mRNA PMID:35307453 14035796 MAFG MAF bZIP transcription factor G gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MAFG mRNA PMID:35307453 14035839 CRABP1 cellular retinoic acid binding protein 1 gene CHEBI:17026 progesterone affects expression EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone affects the expression of CRABP1 protein PMID:11833939 14035952 BCLAF1 BCL2 associated transcription factor 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BCLAF1 mRNA PMID:35307453 14036006 THUMPD1 THUMP domain containing 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of THUMPD1 mRNA; deoxynivalenol results in increased expression of THUMPD1 protein PMID:35307453|PMID:38403181 14036260 NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of NAALAD2 mRNA PMID:28069986 14036405 S1PR5 sphingosine-1-phosphate receptor 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of S1PR5 mRNA PMID:35307453 14036484 DUSP26 dual specificity phosphatase 26 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DUSP26 mRNA PMID:35307453 14036659 PRR7 proline rich 7, synaptic gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRR7 mRNA PMID:35307453 14037166 ACAA2 acetyl-CoA acyltransferase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACAA2 mRNA PMID:35307453 14037257 CDCA2 cell division cycle associated 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDCA2 mRNA PMID:35307453 14037583 LOC100624218 MORN repeat-containing protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MORN1 mRNA PMID:35307453 14037894 SERPINB7 serpin family B member 7 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SERPINB7 mRNA PMID:35307453 14037973 FEZF1 FEZ family zinc finger 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of FEZF1 mRNA PMID:35307453 14038048 ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENTPD2 mRNA PMID:35307453 14038049 ACYP2 acylphosphatase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACYP2 mRNA PMID:35307453 14038221 RGS20 regulator of G protein signaling 20 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RGS20 mRNA PMID:35307453 14038230 TTC13 tetratricopeptide repeat domain 13 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TTC13 mRNA PMID:35307453 14038555 NIPAL3 NIPA like domain containing 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NIPAL3 mRNA PMID:35307453 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of NOS2 mRNA PMID:25701311 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of NOS2 mRNA PMID:23727178 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of NOS2 mRNA PMID:23727178 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:15891 taurine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D013654 Taurine inhibits the reaction [ochratoxin A results in decreased expression of INOS mRNA] PMID:36281498 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] PMID:21375526 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:16412 lipopolysaccharide affects expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides affects the expression of NOS2 mRNA; Lipopolysaccharides affects the expression of NOS2 protein PMID:12893242 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:16480 nitric oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009569 Resveratrol inhibits the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide] PMID:20825639 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:17234 glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of NOS2 protein PMID:16949779 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:17234 glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] PMID:16949779 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:17634 D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of NOS2 protein PMID:16949779 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:17634 D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] PMID:16949779 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOS2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOS2 protein PMID:33592257|PMID:34416349 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:229959 mogroside V multiple interactions EXP E RGD:6480464 20240409 CTD MESH:C041740 mogroside V inhibits the reaction [Particulate Matter results in increased expression of NOS2 mRNA] PMID:35134483 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:27744 glyphosate increases expression EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in increased expression of NOS2 mRNA PMID:35388968 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:27881 resveratrol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased expression of NOS2 protein PMID:20825639 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide] PMID:20825639 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D000111 Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of INOS mRNA] PMID:36281498 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in increased expression of NOS2 mRNA; Cadmium Chloride results in increased expression of NOS2 protein PMID:33626375 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOS2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOS2 protein PMID:33592257|PMID:34416349 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:42758 aldehydo-D-glucose increases expression EXP E RGD:6480464 20191114 CTD MESH:D005947 Glucose results in increased expression of NOS2 protein PMID:16949779 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:42758 aldehydo-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] PMID:16949779 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:4670 dobutamine affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D004280 NOS2 protein affects the susceptibility to Dobutamine PMID:20141602 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20230502 CTD MESH:C025589 ochratoxin A results in increased expression of INOS mRNA PMID:36281498 14038749 NOS2 nitric oxide synthase 2 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C025589 Acetylcysteine inhibits the reaction [ochratoxin A results in increased expression of INOS mRNA]; Taurine inhibits the reaction [ochratoxin A results in decreased expression of INOS mRNA] PMID:36281498 14038799 SURF2 surfeit 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SURF2 mRNA PMID:35307453 14039044 HSPB6 heat shock protein family B (small) member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HSPB6 mRNA PMID:35307453 14039133 PGM2 phosphoglucomutase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in increased expression of PGM2 mRNA; deoxynivalenol results in increased expression of PGM2 protein PMID:38403181 14039183 IL2 interleukin 2 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007262 [Zearalenone co-treated with deoxynivalenol] results in decreased expression of IL2 mRNA PMID:18296887 14039183 IL2 interleukin 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of IL2 mRNA PMID:34933075 14039183 IL2 interleukin 2 gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015025 [Zearalenone co-treated with deoxynivalenol] results in decreased expression of IL2 mRNA PMID:18296887 14039183 IL2 interleukin 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL2 mRNA PMID:33592257 14039183 IL2 interleukin 2 gene CHEBI:35456 cadmium dichloride increases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in increased expression of IL2 mRNA PMID:33626375 14039183 IL2 interleukin 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL2 mRNA PMID:33592257 14039183 IL2 interleukin 2 gene CHEBI:7719 ochratoxin A decreases secretion EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased secretion of IL2 protein PMID:28699257 14039555 PTPRC protein tyrosine phosphatase receptor type C gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of PTPRC mRNA PMID:34389318 14039629 KCNH3 potassium voltage-gated channel subfamily H member 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KCNH3 mRNA PMID:35307453 14039654 TTLL9 tubulin tyrosine ligase like 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TTLL9 mRNA PMID:35307453 14039673 WAPL WAPL cohesin release factor gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of WAPL mRNA PMID:34389318 14039784 ZWILCH zwilch kinetochore protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZWILCH mRNA PMID:35307453 14039818 EP300 E1A binding protein p300 gene CHEBI:10033 warfarin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014859 [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of EP300 protein PMID:29358327 14039992 CORO6 coronin 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CORO6 mRNA PMID:35307453 14040083 USP19 ubiquitin specific peptidase 19 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of USP19 mRNA PMID:35307453 14040177 DDX46 DEAD-box helicase 46 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX46 mRNA PMID:35307453 14040383 IRF7 interferon regulatory factor 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of IRF7 mRNA; deoxynivalenol results in decreased expression of IRF7 protein PMID:38403181 14040383 IRF7 interferon regulatory factor 7 gene CHEBI:3638 chloroquine multiple interactions EXP E RGD:6480464 20200331 CTD MESH:D002738 Chloroquine inhibits the reaction [SZU-101 results in increased expression of IRF7 mRNA] PMID:27079946 14040540 UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of UGT1A6 mRNA PMID:35307453 14040567 SYNPO2L synaptopodin 2 like gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SYNPO2L mRNA PMID:35307453 14040583 HYAL4 hyaluronidase 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of HYAL4 mRNA PMID:35307453 14040609 SH2D2A SH2 domain containing 2A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SH2D2A mRNA PMID:35307453 14040722 MTF2 metal response element binding transcription factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MTF2 mRNA PMID:35307453 14040834 OSR2 odd-skipped related transciption factor 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of OSR2 mRNA PMID:34933075 14040853 PTPRU protein tyrosine phosphatase receptor type U gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PTPRU mRNA PMID:35307453 14040924 CD209 CD209 molecule gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of CD209 mRNA PMID:34933075 14041279 ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ENPP3 mRNA PMID:35307453 14041438 SORD sorbitol dehydrogenase gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SORD mRNA PMID:35307453 14041438 SORD sorbitol dehydrogenase gene CHEBI:6651 malathion increases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in increased expression of SORD mRNA PMID:31535366 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IDH2 mRNA; deoxynivalenol results in decreased expression of IDH2 protein PMID:35307453 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005978 Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:18320 1,4-dithiothreitol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004229 Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:22977 cadmium atom affects binding EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium binds to IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:22977 cadmium atom affects folding EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium affects the folding of IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:22977 cadmium atom decreases activity EXP E RGD:6480464 20191114 CTD MESH:D002104 Cadmium results in decreased activity of IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:22977 cadmium atom decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D002104 IDH2 protein results in decreased susceptibility to Cadmium PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002104 [oxalomalic acid results in decreased activity of IDH2 protein] which results in increased susceptibility to Cadmium; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium results in decreased activity of IDH2 protein]; IDH2 protein inhibits the reaction [Cadmium results in decreased activity of GLRX protein] PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in decreased expression of IDH2 mRNA PMID:21852083 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:30926 3-oxalomalic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:C015407 oxalomalic acid results in decreased activity of IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:30926 3-oxalomalic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C015407 [oxalomalic acid results in decreased activity of IDH2 protein] which results in increased susceptibility to Cadmium; [oxalomalic acid results in decreased activity of IDH2 protein] which results in increased susceptibility to Cadmium Chloride PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:35456 cadmium dichloride affects binding EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride binds to IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:35456 cadmium dichloride affects folding EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride affects the folding of IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:35456 cadmium dichloride decreases activity EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in decreased activity of IDH2 protein PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:35456 cadmium dichloride decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D019256 IDH2 protein results in decreased susceptibility to Cadmium Chloride PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019256 [oxalomalic acid results in decreased activity of IDH2 protein] which results in increased susceptibility to Cadmium Chloride; Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; IDH2 protein inhibits the reaction [Cadmium Chloride results in decreased activity of GLRX protein] PMID:16785314 14041463 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:42106 L-1,4-dithiothreitol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004229 Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] PMID:16785314 14041486 BLVRB biliverdin reductase B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of BLVRB mRNA PMID:35307453 14041514 INTS12 integrator complex subunit 12 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of INTS12 mRNA PMID:35307453 14041581 AMPH amphiphysin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AMPH mRNA PMID:35307453 14041729 ZNF277 zinc finger protein 277 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZNF277 mRNA PMID:35307453 14041751 ZP3 zona pellucida glycoprotein 3 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of ZP3 mRNA PMID:26386189 14041751 ZP3 zona pellucida glycoprotein 3 gene CHEBI:10106 zearalenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015025 Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of ZP3 mRNA] PMID:26386189 14041751 ZP3 zona pellucida glycoprotein 3 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of ZP3 mRNA] PMID:26386189 14041896 BUB1 BUB1 mitotic checkpoint serine/threonine kinase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BUB1 mRNA PMID:35307453 14041929 ERO1A endoplasmic reticulum oxidoreductase 1 alpha gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ERO1A mRNA PMID:35307453 14041929 ERO1A endoplasmic reticulum oxidoreductase 1 alpha gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ERO1A mRNA PMID:33891997 14041929 ERO1A endoplasmic reticulum oxidoreductase 1 alpha gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20211012 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ERO1A mRNA PMID:33891997 14041988 PERM1 PPARGC1 and ESRR induced regulator, muscle 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PERM1 mRNA PMID:35307453 14042125 ABHD1 abhydrolase domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ABHD1 mRNA PMID:35307453 14042221 IL23R interleukin 23 receptor gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of IL23R mRNA PMID:34933075 14042450 HLX H2.0 like homeobox gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HLX mRNA PMID:35307453 14042587 ELFN2 extracellular leucine rich repeat and fibronectin type III domain containing 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ELFN2 mRNA PMID:35307453 14042628 F12 coagulation factor XII gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of F12 mRNA PMID:35307453 14042628 F12 coagulation factor XII gene CHEBI:16134 ammonia decreases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in decreased expression of F12 mRNA PMID:34389318 14042757 DCX doublecortin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DCX mRNA PMID:35307453 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230502 CTD MESH:C007262 deoxynivalenol results in decreased expression of PPARG mRNA; deoxynivalenol results in decreased expression of PPARG protein PMID:36596350 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPARG mRNA PMID:35307453 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20230502 CTD MESH:C007262 [Rosiglitazone co-treated with deoxynivalenol] results in decreased expression of PPARG protein; [Troglitazone co-treated with deoxynivalenol] results in decreased expression of PPARG protein; PPARG protein affects the reaction [Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; PPARG protein affects the reaction [Rosiglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; T 0070907 inhibits the reaction [[Rosiglitazone co-treated with deoxynivalenol] results in decreased expression of PPARG protein]; T 0070907 inhibits the reaction [[Troglitazone co-treated with deoxynivalenol] results in decreased expression of PPARG protein] PMID:36596350 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein] PMID:15051824 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:16796 melatonin multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D008550 Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG protein] PMID:31535366 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:17154 nicotinamide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009536 Niacinamide results in increased expression of PPARG mRNA PMID:17851734 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:17270 glycerol 2-phosphate multiple interactions EXP E RGD:6480464 20191210 CTD MESH:C031463 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] PMID:30481989 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:17351 linoleic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:D019787 Linoleic Acid results in increased activity of PPARG protein PMID:15051824 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:17351 linoleic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019787 PPARG protein promotes the reaction [Linoleic Acid results in increased activity of RELA protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein]; Vitamin E inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein] PMID:14519784|PMID:15051824 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:27363 zinc atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased expression of PPARG mRNA PMID:14519784 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:27363 zinc atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015032 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of and results in increased activity of PPARG protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of PPARG mRNA]; Zinc results in increased expression of and results in increased activity of PPARG protein PMID:14519784 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:27881 resveratrol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased expression of PPARG mRNA; Resveratrol results in decreased expression of PPARG protein PMID:17851734|PMID:21575630 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Dietary Fats results in decreased expression of PPARG protein] PMID:21739664 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:29073 L-ascorbic acid multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D001205 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] PMID:30481989 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:30185 zinc(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D015032 Zinc results in increased expression of PPARG mRNA PMID:14519784 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:30185 zinc(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015032 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of and results in increased activity of PPARG protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of PPARG mRNA]; Zinc results in increased expression of and results in increased activity of PPARG protein PMID:14519784 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:33234 vitamin E multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D024502 Vitamin E inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein] PMID:15051824 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:34578 Bisphenol A diglycidyl ether multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C019273 bisphenol A diglycidyl ether binds to and results in decreased activity of PPARG protein; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Troglitazone results in increased activity of PPARG protein] PMID:14506076|PMID:14519784|PMID:30481989 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:41879 dexamethasone increases expression EXP E RGD:6480464 20191114 CTD MESH:D003907 Dexamethasone results in increased expression of PPARG PMID:19852296 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:41879 dexamethasone multiple interactions EXP E RGD:6480464 20191210 CTD MESH:D003907 [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; bisphenol A diglycidyl ether inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] PMID:30481989 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:50992 1,3-thiazolidine-2,4-dione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C089946 2,4-thiazolidinedione binds to and results in increased activity of PPARG protein PMID:14519784 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:6651 malathion decreases expression EXP E RGD:6480464 20201103 CTD MESH:D008294 Malathion results in decreased expression of PPARG mRNA; Malathion results in decreased expression of PPARG protein PMID:31535366 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:6651 malathion multiple interactions EXP E RGD:6480464 20201103 CTD MESH:D008294 Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG protein] PMID:31535366 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:75261 arotinoid acid decreases expression EXP E RGD:6480464 20191114 CTD MESH:C038864 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased expression of PPARG mRNA PMID:15583048 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:8228 pioglitazone increases activity EXP E RGD:6480464 20191114 CTD MESH:C060836 Pioglitazone results in increased activity of PPARG protein PMID:17065204 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:8228 pioglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C060836 Troglitazone inhibits the reaction [Pioglitazone results in increased activity of PPARG protein] PMID:17065204 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:88217 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C044387 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of and results in increased activity of PPARG protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of PPARG mRNA] PMID:14519784 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:9753 troglitazone decreases expression EXP E RGD:6480464 20230502 CTD MESH:C057693 Troglitazone results in decreased expression of PPARG mRNA; Troglitazone results in decreased expression of PPARG protein PMID:36596350 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:9753 troglitazone increases activity EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone results in increased activity of PPARG protein PMID:14506076 14042986 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 [Troglitazone co-treated with deoxynivalenol] results in decreased expression of PPARG protein; bisphenol A diglycidyl ether inhibits the reaction [Troglitazone results in increased activity of PPARG protein]; PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN3 protein]]; PPARG protein affects the reaction [Troglitazone inhibits the reaction [deoxynivalenol results in decreased expression of CLDN4 protein]]; T 0070907 inhibits the reaction [[Troglitazone co-treated with deoxynivalenol] results in decreased expression of PPARG protein]; Troglitazone inhibits the reaction [Pioglitazone results in increased activity of PPARG protein]; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] PMID:14506076|PMID:17065204|PMID:30481989|PMID:36596350 14043058 NFKBIB NFKB inhibitor beta gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NFKBIB mRNA PMID:35307453 14043072 LMAN2L lectin, mannose binding 2 like gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LMAN2L mRNA PMID:35307453 14043101 INS insulin gene CHEBI:134261 alpha-(methylamino)isobutyric acid increases uptake EXP E RGD:6480464 20191114 CTD MESH:C017911 INS protein results in increased uptake of 2-(methylamino)isobutyric acid PMID:1928324 14043101 INS insulin gene CHEBI:134261 alpha-(methylamino)isobutyric acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C017911 Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]]; oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid] PMID:1928324 14043101 INS insulin gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of INS protein PMID:9185964 14043101 INS insulin gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008070 GH1 protein inhibits the reaction [Lipopolysaccharides results in decreased expression of INS protein] PMID:9185964 14043101 INS insulin gene CHEBI:16422 androst-4-ene-3,17-dione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000735 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; [LHB protein co-treated with INS protein] results in increased abundance of Androstenedione; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione] PMID:11889176 14043101 INS insulin gene CHEBI:17234 glucose increases transport EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein results in increased transport of Glucose PMID:8048502 14043101 INS insulin gene CHEBI:17234 glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] PMID:20622751|PMID:8048502|PMID:8699633 14043101 INS insulin gene CHEBI:17347 testosterone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013739 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; [LHB protein co-treated with INS protein] results in increased abundance of Testosterone; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone] PMID:11889176 14043101 INS insulin gene CHEBI:17634 D-glucose increases transport EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein results in increased transport of Glucose PMID:8048502 14043101 INS insulin gene CHEBI:17634 D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] PMID:20622751|PMID:8048502|PMID:8699633 14043101 INS insulin gene CHEBI:27485 prostaglandin J2 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C037112 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA] PMID:11889176 14043101 INS insulin gene CHEBI:28073 chromium atom decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002857 Chromium results in decreased expression of INS protein PMID:7628956 14043101 INS insulin gene CHEBI:42758 aldehydo-D-glucose increases transport EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein results in increased transport of Glucose PMID:8048502 14043101 INS insulin gene CHEBI:42758 aldehydo-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] PMID:20622751|PMID:8048502|PMID:8699633 14043101 INS insulin gene CHEBI:50369 tris(picolinato)chromium decreases expression EXP E RGD:6480464 20191114 CTD MESH:C079689 chromium tripicolinate results in decreased expression of INS protein PMID:7628956 14043101 INS insulin gene CHEBI:64198 dimercaprol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004112 Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]] PMID:1928324 14043101 INS insulin gene CHEBI:75253 phenylarsine oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C029341 Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid] PMID:1928324|PMID:8048502 14043101 INS insulin gene CHEBI:9168 sirolimus decreases expression EXP E RGD:6480464 20191114 CTD MESH:D020123 Sirolimus results in decreased expression of INS mRNA; Sirolimus results in decreased expression of INS protein PMID:20622751 14043101 INS insulin gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020123 Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] PMID:20622751 14043101 INS insulin gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 protein modified form] PMID:11889176 14043135 PLCD3 phospholipase C delta 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PLCD3 mRNA PMID:35307453 14043181 MFSD3 major facilitator superfamily domain containing 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MFSD3 mRNA PMID:35307453 14043218 CLPSL2 colipase like 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CLPSL2 mRNA PMID:35307453 14043276 AKT3 AKT serine/threonine kinase 3 gene CHEBI:50842 norflurazon decreases phosphorylation EXP E RGD:6480464 20240903 CTD MESH:C008677 norflurazone results in decreased phosphorylation of AKT3 protein PMID:38432436 14043378 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol results in decreased expression of CDKN1A mRNA; deoxynivalenol results in decreased expression of CDKN1A protein PMID:38104654 14043378 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CDKN1A mRNA PMID:35307453 14043378 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:10033 warfarin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014859 [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of CDKN1A protein PMID:29358327 14043378 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of CDKN1A mRNA PMID:27617619 14043378 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in increased expression of CDKN1A protein PMID:28819136 14043378 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:46195 paracetamol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000082 Acetaminophen results in decreased expression of CDKN1A protein PMID:16330492 14043408 TOX thymocyte selection associated high mobility group box gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TOX mRNA PMID:35307453 14043494 ADGRV1 adhesion G protein-coupled receptor V1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ADGRV1 mRNA PMID:35307453 14043606 LCN2 lipocalin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LCN2 mRNA PMID:35307453 14043606 LCN2 lipocalin 2 gene CHEBI:38221 fumonisin B1 increases expression EXP E RGD:6480464 20240903 CTD MESH:C056933 fumonisin B1 results in increased expression of LCN2 mRNA PMID:38705344 14043606 LCN2 lipocalin 2 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C056933 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of LCN2 mRNA; necrostatin-1 inhibits the reaction [fumonisin B1 results in increased expression of LCN2 mRNA] PMID:33905761|PMID:38705344 14043606 LCN2 lipocalin 2 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20211012 CTD MESH:C025589 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of LCN2 mRNA PMID:33905761 14043922 CEP170 centrosomal protein 170 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CEP170 mRNA PMID:35307453 14044060 GZMK granzyme K gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GZMK mRNA PMID:35307453 14044069 AEN apoptosis enhancing nuclease gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AEN mRNA PMID:35307453 14044077 CMTM7 CKLF like MARVEL transmembrane domain containing 7 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CMTM7 mRNA PMID:35307453 14044217 TMEM248 transmembrane protein 248 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMEM248 mRNA PMID:35307453 14044243 RBBP8NL RBBP8 N-terminal like gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in increased expression of RBBP8NL mRNA PMID:34933075 14044419 CTSB cathepsin B gene CHEBI:17026 progesterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone results in increased expression of CTSB mRNA PMID:20107207 14044419 CTSB cathepsin B gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013749 Tetrachlorodibenzodioxin results in decreased expression of CTSB mRNA PMID:16291828 14044419 CTSB cathepsin B gene CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP E RGD:6480464 20191114 CTD MESH:C023035 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CTSB mRNA PMID:16291828 14044419 CTSB cathepsin B gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of CTSB mRNA PMID:16896063 14044626 REG3G regenerating islet-derived 3 gamma gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of REG3G mRNA PMID:35307453 14044757 SAP18 Sin3A associated protein 18 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SAP18 mRNA PMID:35307453 14044801 ZNHIT6 zinc finger HIT-type containing 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNHIT6 mRNA PMID:35307453 14044858 GCFC2 GC-rich sequence DNA-binding factor 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GCFC2 mRNA PMID:35307453 14044917 AKIRIN2 akirin 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of AKIRIN2 mRNA PMID:35307453 14044932 SLC7A4 solute carrier family 7 member 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC7A4 mRNA PMID:35307453 14044932 SLC7A4 solute carrier family 7 member 4 gene CHEBI:16236 ethanol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased expression of SLC7A4 mRNA PMID:28069986 14045003 RGS9 regulator of G protein signaling 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RGS9 mRNA PMID:35307453 14045078 TES testin LIM domain protein gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TES mRNA PMID:35307453 14045293 SH3YL1 SH3 and SYLF domain containing 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SH3YL1 mRNA PMID:35307453 14045384 RHBDD2 rhomboid domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of RHBDD2 mRNA PMID:35307453 14045548 GSTA4 glutathione S-transferase alpha 4 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GSTA4 mRNA PMID:35307453 14045563 SOD1 superoxide dismutase 1 gene CHEBI:10022 deoxynivalenol increases activity EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased activity of SOD1 protein PMID:37442268 14045563 SOD1 superoxide dismutase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20240806 CTD MESH:C007262 deoxynivalenol results in increased expression of SOD1 protein PMID:38104654 14045563 SOD1 superoxide dismutase 1 gene CHEBI:10022 deoxynivalenol multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C007262 Selenium analog inhibits the reaction [deoxynivalenol results in increased activity of SOD1 protein] PMID:37442268 14045563 SOD1 superoxide dismutase 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of SOD1 mRNA PMID:23727178 14045563 SOD1 superoxide dismutase 1 gene CHEBI:144353 diethyldithiocarbamic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004050 Ditiocarb results in decreased activity of SOD1 protein PMID:11861319 14045563 SOD1 superoxide dismutase 1 gene CHEBI:144353 diethyldithiocarbamic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004050 SOD1 protein affects the susceptibility to [Ditiocarb co-treated with 6-anilino-5,8-quinolinedione] PMID:11861319 14045563 SOD1 superoxide dismutase 1 gene CHEBI:15354 choline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002794 [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA PMID:29129240 14045563 SOD1 superoxide dismutase 1 gene CHEBI:16236 ethanol decreases activity EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in decreased activity of SOD1 protein PMID:16792574 14045563 SOD1 superoxide dismutase 1 gene CHEBI:16236 ethanol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000431 [Ethanol co-treated with Folic Acid deficiency] results in decreased activity of SOD1 protein PMID:16792574 14045563 SOD1 superoxide dismutase 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 [sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide PMID:12530527 14045563 SOD1 superoxide dismutase 1 gene CHEBI:16412 lipopolysaccharide decreases expression EXP E RGD:6480464 20230704 CTD MESH:D008070 Lipopolysaccharides results in decreased expression of SOD1 mRNA PMID:36549457 14045563 SOD1 superoxide dismutase 1 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20230704 CTD MESH:D008070 Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD1 mRNA] PMID:36549457 14045563 SOD1 superoxide dismutase 1 gene CHEBI:17439 cyanocob(III)alamin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014805 [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA PMID:29129240 14045563 SOD1 superoxide dismutase 1 gene CHEBI:17750 glycine betaine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001622 [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA PMID:29129240 14045563 SOD1 superoxide dismutase 1 gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20231031 CTD MESH:D002104 Cadmium results in increased expression of SOD1 mRNA PMID:37207789 14045563 SOD1 superoxide dismutase 1 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SOD1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SOD1 mRNA; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of SOD1 mRNA] PMID:33493553|PMID:34416349|PMID:37207789 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27363 zinc atom multiple interactions EXP E RGD:6480464 20210907 CTD MESH:D015032 [Zinc binds to alpha-hydroxy-gamma-methylmercaptobutyric acid] inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA] PMID:32280687 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27470 folic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D005492 Folic Acid deficiency results in decreased activity of SOD1 protein PMID:16792574 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005492 [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA; [Ethanol co-treated with Folic Acid deficiency] results in decreased activity of SOD1 protein PMID:16792574|PMID:29129240 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27568 selenium atom multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased activity of SOD1 protein] PMID:37442268 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27584 aldosterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D000450 Aldosterone results in increased expression of SOD1 protein PMID:24512358 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27744 glyphosate decreases activity EXP E RGD:6480464 20240206 CTD MESH:C010974 Glyphosate results in decreased activity of SOD1 protein PMID:35388968 14045563 SOD1 superoxide dismutase 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20230704 CTD MESH:C059514 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of SOD1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of SOD1 protein]; Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD1 mRNA] PMID:36549457|PMID:37955343 14045563 SOD1 superoxide dismutase 1 gene CHEBI:29678 sodium arsenite increases activity EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in increased activity of SOD1 protein PMID:12530527 14045563 SOD1 superoxide dismutase 1 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C017947 [sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide PMID:12530527 14045563 SOD1 superoxide dismutase 1 gene CHEBI:30185 zinc(0) multiple interactions EXP E RGD:6480464 20210907 CTD MESH:D015032 [Zinc binds to alpha-hydroxy-gamma-methylmercaptobutyric acid] inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA] PMID:32280687 14045563 SOD1 superoxide dismutase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of SOD1 mRNA PMID:29129240 14045563 SOD1 superoxide dismutase 1 gene CHEBI:34631 chlorpyrifos decreases expression EXP E RGD:6480464 20231205 CTD MESH:D004390 Chlorpyrifos results in decreased expression of SOD1 mRNA PMID:34399389|PMID:38565334 14045563 SOD1 superoxide dismutase 1 gene CHEBI:34905 paraquat increases expression EXP E RGD:6480464 20230704 CTD MESH:D010269 Paraquat results in increased expression of SOD1 mRNA PMID:36615853 14045563 SOD1 superoxide dismutase 1 gene CHEBI:34905 paraquat multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D010269 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA]; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA; [MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 protein; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA] PMID:34811946 14045563 SOD1 superoxide dismutase 1 gene CHEBI:35176 zinc sulfate multiple interactions EXP E RGD:6480464 20210907 CTD MESH:D019287 Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA] PMID:32280687 14045563 SOD1 superoxide dismutase 1 gene CHEBI:35456 cadmium dichloride decreases expression EXP E RGD:6480464 20210504 CTD MESH:D019256 Cadmium Chloride results in decreased expression of SOD1 mRNA PMID:33626375 14045563 SOD1 superoxide dismutase 1 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SOD1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SOD1 mRNA PMID:33493553|PMID:34416349 14045563 SOD1 superoxide dismutase 1 gene CHEBI:36904 elemental selenium multiple interactions EXP E RGD:6480464 20231031 CTD MESH:D012643 Selenium analog inhibits the reaction [deoxynivalenol results in increased activity of SOD1 protein] PMID:37442268 14045563 SOD1 superoxide dismutase 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of SOD1 mRNA PMID:17437637 14045563 SOD1 superoxide dismutase 1 gene CHEBI:38221 fumonisin B1 decreases expression EXP E RGD:6480464 20240604 CTD MESH:C056933 fumonisin B1 results in decreased expression of SOD1 mRNA; fumonisin B1 results in decreased expression of SOD1 protein PMID:37955343 14045563 SOD1 superoxide dismutase 1 gene CHEBI:38221 fumonisin B1 multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C056933 Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of SOD1 mRNA]; Resveratrol inhibits the reaction [fumonisin B1 results in decreased expression of SOD1 protein] PMID:37955343 14045563 SOD1 superoxide dismutase 1 gene CHEBI:38635 3-methyladenine multiple interactions EXP E RGD:6480464 20230905 CTD MESH:C025946 3-methyladenine affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA] PMID:34811946 14045563 SOD1 superoxide dismutase 1 gene CHEBI:4027 cyclophosphamide decreases expression EXP E RGD:6480464 20240109 CTD MESH:D003520 Cyclophosphamide results in decreased expression of SOD1 mRNA PMID:37980972 14045563 SOD1 superoxide dismutase 1 gene CHEBI:4027 cyclophosphamide multiple interactions EXP E RGD:6480464 20240109 CTD MESH:D003520 Panobinostat inhibits the reaction [Cyclophosphamide results in decreased expression of SOD1 mRNA] PMID:37980972 14045563 SOD1 superoxide dismutase 1 gene CHEBI:64163 diquat decreases expression EXP E RGD:6480464 20210907 CTD MESH:D004178 Diquat results in decreased expression of SOD1 mRNA PMID:32280687|PMID:38567716 14045563 SOD1 superoxide dismutase 1 gene CHEBI:64163 diquat multiple interactions EXP E RGD:6480464 20210907 CTD MESH:D004178 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA]; [Zinc binds to alpha-hydroxy-gamma-methylmercaptobutyric acid] inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA]; Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA] PMID:32280687|PMID:38567716 14045563 SOD1 superoxide dismutase 1 gene CHEBI:7719 ochratoxin A decreases activity EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased activity of SOD1 protein PMID:18547704 14045563 SOD1 superoxide dismutase 1 gene CHEBI:78677 6-anilino-5,8-quinolinedione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C041715 SOD1 protein affects the susceptibility to [Ditiocarb co-treated with 6-anilino-5,8-quinolinedione] PMID:11861319 14045563 SOD1 superoxide dismutase 1 gene CHEBI:80774 tauroursodeoxycholic acid multiple interactions EXP E RGD:6480464 20231031 CTD MESH:C031655 ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of SOD1 mRNA] PMID:37207789 14045563 SOD1 superoxide dismutase 1 gene CHEBI:85990 panobinostat multiple interactions EXP E RGD:6480464 20240109 CTD MESH:C496932 Panobinostat inhibits the reaction [Cyclophosphamide results in decreased expression of SOD1 mRNA] PMID:37980972 14045563 SOD1 superoxide dismutase 1 gene CHEBI:9168 sirolimus multiple interactions EXP E RGD:6480464 20230905 CTD MESH:D020123 Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA] PMID:34811946 14045624 CCL24 C-C motif chemokine ligand 24 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCL24 mRNA PMID:34416349 14045624 CCL24 C-C motif chemokine ligand 24 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCL24 mRNA PMID:34416349 14045661 NOX1 NADPH oxidase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of NOX1 mRNA PMID:35307453 14045661 NOX1 NADPH oxidase 1 gene CHEBI:17561 L-cysteine multiple interactions EXP E RGD:6480464 20240206 CTD MESH:D003545 Cysteine inhibits the reaction [bisphenol A results in decreased expression of NOX1 mRNA] PMID:37999554 14045661 NOX1 NADPH oxidase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20240206 CTD MESH:C006780 bisphenol A results in decreased expression of NOX1 mRNA PMID:37999554 14045661 NOX1 NADPH oxidase 1 gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20240206 CTD MESH:C006780 Cysteine inhibits the reaction [bisphenol A results in decreased expression of NOX1 mRNA] PMID:37999554 14045709 MYH3 myosin heavy chain 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of MYH3 mRNA PMID:35307453 14045921 ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ST3GAL5 mRNA PMID:35307453 14045981 GLT8D2 glycosyltransferase 8 domain containing 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of GLT8D2 mRNA PMID:35307453 14046212 KATNIP katanin interacting protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KATNIP mRNA PMID:35307453 14046285 TMC1 transmembrane channel like 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of TMC1 mRNA PMID:35307453 14046333 CCL19 C-C motif chemokine ligand 19 gene CHEBI:25434 bis(2-chloroethyl) sulfide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009151 Mustard Gas results in increased expression of CCL19 mRNA PMID:18988085 14046346 DDX21 DExD-box helicase 21 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX21 mRNA PMID:35307453 14046594 ERAP2 endoplasmic reticulum aminopeptidase 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ERAP2 mRNA PMID:35307453 14046846 DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DYNC1I1 mRNA PMID:35307453 14046960 RLIM ring finger protein, LIM domain interacting gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RLIM mRNA PMID:35307453 14047051 NKX2-2 NK2 homeobox 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NKX2-2 mRNA PMID:35307453 14047160 ZNF598 zinc finger protein 598, E3 ubiquitin ligase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF598 mRNA PMID:35307453 14047280 GATA6 GATA binding protein 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GATA6 mRNA PMID:35307453 14047306 CEP72 centrosomal protein 72 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CEP72 mRNA PMID:35307453 14047361 MYPOP Myb related transcription factor, partner of profilin gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of MYPOP mRNA PMID:35307453 14047372 PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PYROXD1 mRNA PMID:35307453 14047424 STX10 syntaxin 10 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of STX10 mRNA PMID:35307453 14047441 DAD1 defender against cell death 1 gene CHEBI:7719 ochratoxin A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C025589 ochratoxin A results in decreased expression of DAD1 mRNA PMID:14994279 14047448 CYSRT1 cysteine rich tail 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CYSRT1 mRNA PMID:35307453 14047481 CTSH cathepsin H gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CTSH mRNA PMID:35307453 14047686 FOXA2 forkhead box A2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FOXA2 mRNA PMID:35307453 14047786 OSMR oncostatin M receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of OSMR mRNA PMID:35307453 14047858 ANP32E acidic nuclear phosphoprotein 32 family member E gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20231031 CTD MESH:C007262 deoxynivalenol results in increased expression of ANP32E protein PMID:37257635 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C006780 bisphenol A results in decreased expression of DICER1 mRNA; bisphenol A results in decreased expression of DICER1 protein PMID:31266599 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:33216 bisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006780 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in decreased expression of DICER1 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of DICER1 mRNA PMID:31266599 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C020806 tetrabromobisphenol A results in decreased expression of DICER1 mRNA; tetrabromobisphenol A results in decreased expression of DICER1 protein PMID:31266599 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:33217 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C020806 [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 protein PMID:31266599 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:35004 Tetrachlorobisphenol A decreases expression EXP E RGD:6480464 20191114 CTD MESH:C041181 tetrachlorodian results in decreased expression of DICER1 mRNA PMID:31266599 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:35004 Tetrachlorobisphenol A increases expression EXP E RGD:6480464 20191114 CTD MESH:C041181 tetrachlorodian results in increased expression of DICER1 protein PMID:31266599 14047912 DICER1 dicer 1, ribonuclease III gene CHEBI:35004 Tetrachlorobisphenol A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C041181 [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrachlorodian] results in decreased expression of DICER1 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrachlorodian] results in increased expression of DICER1 protein PMID:31266599 14048037 KCNIP2 potassium voltage-gated channel interacting protein 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of KCNIP2 mRNA PMID:35307453 14048072 PPP1R12A protein phosphatase 1 regulatory subunit 12A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PPP1R12A mRNA PMID:35307453 14048173 BMPER BMP binding endothelial regulator gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of BMPER mRNA PMID:35307453 14048348 DDX50 DExD-box helicase 50 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of DDX50 mRNA PMID:35307453 14048391 ASRGL1 asparaginase and isoaspartyl peptidase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ASRGL1 mRNA PMID:35307453 14048391 ASRGL1 asparaginase and isoaspartyl peptidase 1 gene CHEBI:16134 ammonia increases expression EXP E RGD:6480464 20220308 CTD MESH:D000641 Ammonia results in increased expression of ASRGL1 mRNA PMID:34389318 14048406 CIB2 calcium and integrin binding family member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of CIB2 mRNA PMID:35307453 14048438 UROC1 urocanate hydratase 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of UROC1 mRNA PMID:35307453 14048634 NEFH neurofilament heavy chain gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NEFH mRNA PMID:35307453 14048634 NEFH neurofilament heavy chain gene CHEBI:88522 Monobutylphthalate increases expression EXP E RGD:6480464 20240402 CTD MESH:C028577 monobutyl phthalate results in increased expression of NEFH mRNA PMID:35839969 14048673 HK2 hexokinase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HK2 mRNA PMID:35307453 14048673 HK2 hexokinase 2 gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 mRNA PMID:34416349 14048673 HK2 hexokinase 2 gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20220111 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 mRNA PMID:34416349 14048673 HK2 hexokinase 2 gene CHEBI:4670 dobutamine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004280 Dobutamine results in decreased expression of HK2 protein PMID:19944370 14048703 PPBP pro-platelet basic protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PPBP mRNA PMID:35307453 14048703 PPBP pro-platelet basic protein gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Dietary Fats co-treated with Resveratrol] results in increased expression of PPBP mRNA PMID:21852083 14048722 PRRT3 proline rich transmembrane protein 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRRT3 mRNA PMID:35307453 14048761 HSPA6 heat shock protein family A (Hsp70) member 6 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HSPA6 mRNA PMID:35307453 14048775 CPM carboxypeptidase M gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of CPM mRNA PMID:35307453 14048794 TNS1 tensin 1 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20220705 CTD MESH:D015025 Zearalenone results in decreased expression of TNS1 mRNA PMID:34933075 14048832 HTR2B 5-hydroxytryptamine receptor 2B gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of HTR2B mRNA PMID:35307453 14048849 C17H20orf173 chromosome 17 C20orf173 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of C17H20ORF173 mRNA PMID:35307453 14048916 ISCU iron-sulfur cluster assembly enzyme gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of ISCU mRNA; deoxynivalenol results in decreased expression of ISCU protein PMID:38403181 14048925 IQCD IQ motif containing D gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of IQCD mRNA PMID:35307453 14048970 AMN1 antagonist of mitotic exit network 1 homolog gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of AMN1 mRNA PMID:35307453 14049014 ACSM2B acyl-CoA synthetase medium chain family member 2B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20250128 CTD MESH:C007262 deoxynivalenol results in decreased expression of ACSM2B mRNA PMID:35307453 14049297 LTBP3 latent transforming growth factor beta binding protein 3 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of LTBP3 mRNA PMID:35307453 14049354 TNIP3 TNFAIP3 interacting protein 3 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TNIP3 mRNA PMID:35307453 14049390 PIGR polymeric immunoglobulin receptor gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PIGR mRNA PMID:35307453 14049434 SLC43A2 solute carrier family 43 member 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC43A2 mRNA PMID:35307453 14049518 SUOX sulfite oxidase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SUOX mRNA PMID:35307453 14049537 SLC6A6 solute carrier family 6 member 6 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of SLC6A6 mRNA PMID:35307453 14049592 SETDB1 SET domain bifurcated histone lysine methyltransferase 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20191114 CTD MESH:C007262 deoxynivalenol results in increased expression of SETDB1 mRNA PMID:26988607 14049648 PKNOX2 PBX/knotted 1 homeobox 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PKNOX2 mRNA PMID:35307453 14049682 GSS glutathione synthetase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of GSS mRNA PMID:35307453 14049682 GSS glutathione synthetase gene CHEBI:16236 ethanol increases activity EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased activity of GSS protein PMID:16792574 14049682 GSS glutathione synthetase gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of GSS mRNA PMID:16792574 14049682 GSS glutathione synthetase gene CHEBI:16236 ethanol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000431 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSS protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSS mRNA PMID:16792574 14049682 GSS glutathione synthetase gene CHEBI:27470 folic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005492 [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSS protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSS mRNA PMID:16792574 14049797 NRP2 neuropilin 2 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of NRP2 mRNA PMID:35307453 14049829 TMEM98 transmembrane protein 98 gene CHEBI:16236 ethanol increases expression EXP E RGD:6480464 20191114 CTD MESH:D000431 Ethanol results in increased expression of TMEM98 mRNA PMID:28069986 14049847 SLC9B1 solute carrier family 9 member B1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of SLC9B1 mRNA PMID:35307453 14049869 RAB2B RAB2B, member RAS oncogene family gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of RAB2B mRNA PMID:35307453 14049884 ERC2 ELKS/RAB6-interacting/CAST family member 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ERC2 mRNA PMID:35307453 14050448 TEX10 testis expressed 10 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of TEX10 mRNA PMID:35307453 14050467 PRXL2B peroxiredoxin like 2B gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of PRXL2B mRNA PMID:35307453 14050487 SP110 SP110 nuclear body protein gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20240903 CTD MESH:C007262 deoxynivalenol results in decreased expression of SP110 mRNA; deoxynivalenol results in decreased expression of SP110 protein PMID:38403181 14050649 ZBP1 Z-DNA binding protein 1 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of ZBP1 mRNA PMID:35307453 14050710 FYN FYN proto-oncogene, Src family tyrosine kinase gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FYN mRNA PMID:35307453 14050758 MFF mitochondrial fission factor gene CHEBI:22977 cadmium atom multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D002104 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFF mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFF protein PMID:33493553 14050758 MFF mitochondrial fission factor gene CHEBI:35456 cadmium dichloride multiple interactions EXP E RGD:6480464 20210504 CTD MESH:D019256 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFF mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFF protein PMID:33493553 14050836 KMT2A lysine methyltransferase 2A gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of KMT2A mRNA PMID:35307453 14050902 FUBP1 far upstream element binding protein 1 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of FUBP1 mRNA PMID:35307453 14051022 DNAAF9 dynein axonemal assembly factor 9 gene CHEBI:10022 deoxynivalenol decreases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in decreased expression of DNAAF9 mRNA PMID:35307453 14051071 ZNF783 zinc finger protein 783 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of ZNF783 mRNA PMID:35307453 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:10022 deoxynivalenol increases expression EXP E RGD:6480464 20230117 CTD MESH:C007262 deoxynivalenol results in increased expression of PTGS2 mRNA PMID:35307453 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:10106 zearalenone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in decreased expression of PTGS2 mRNA PMID:23727178 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:10106 zearalenone increases expression EXP E RGD:6480464 20191114 CTD MESH:D015025 Zearalenone results in increased expression of PTGS2 mRNA PMID:23727178 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:15365 acetylsalicylic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001241 Aspirin promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] PMID:10706128 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:15428 glycine multiple interactions EXP E RGD:6480464 20200804 CTD MESH:D005998 [Folic Acid co-treated with Glycine] results in increased expression of PTGS2 PMID:14662146 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:15551 prostaglandin E2 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015232 [Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; alpha-Linolenic Acid inhibits the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Linoleic Acid promotes the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Polychlorinated Biphenyls promotes the reaction [[Linoleic Acid results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Resveratrol inhibits the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone] PMID:18155686|PMID:20825639 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:15553 prostaglandin F2alpha multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015237 [epostane co-treated with Dinoprost] results in increased expression of PTGS2 mRNA PMID:20739670 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:15891 taurine multiple interactions EXP E RGD:6480464 20230502 CTD MESH:D013654 Taurine inhibits the reaction [ochratoxin A results in decreased expression of PTGS2 mRNA] PMID:36281498 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:16112 chlorogenic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002726 Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] PMID:27861533 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased expression of PTGS2 mRNA PMID:26180592|PMID:27861533 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008070 3',4',5'-trimethoxyflavone analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Apigenin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] PMID:26180592|PMID:27861533 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:16469 17beta-estradiol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol results in increased expression of PTGS2 mRNA PMID:21705055 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:16469 17beta-estradiol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004958 Fulvestrant inhibits the reaction [Estradiol results in increased expression of PTGS2 mRNA] PMID:21705055 14051082 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:1723