# RGD-PIPELINE: ftp-file-extracts # MODULE: annotations-version-1.1.9 (Oct 10, 2019) # GENERATED-ON: 2024/11/30 # PURPOSE: annotations about active Green Monkey objects extracted from RGD database # ONTOLOGY: PW: Pathway Ontology # CONTACT: rgd.data@mcw.edu # FORMAT: tab delimited text # NOTES: multiple values in a single column are separated by '|' # #COLUMN INFORMATION: # #1 RGD_ID unique RGD_ID of the annotated object #2 OBJECT_SYMBOL official symbol of the annotated object #3 OBJECT_NAME official name of the annotated object #4 OBJECT_TYPE annotated object data type: one of ['gene','qtl','strain'] #5 TERM_ACC_ID ontology term accession id #6 TERM_NAME ontology term name #7 QUALIFIER optional qualifier #8 EVIDENCE evidence #9 WITH with info #10 ASPECT aspect #11 REFERENCES db references (Reference RGDID|PUBMED ID) #12 CREATED_DATE created date #13 ASSIGNED_BY assigned by #14 MESH_OMIM_ID MESH:xxx or OMIM:xxx id corresponding to RDO:xxx id found in TERM_ACC_ID column (RGD/CTD Disease Ontology annotations only) #15 CURATION_NOTES curation notes provided by RGD curators #16 ORIGINAL_REFERENCE original reference RGD_ID OBJECT_SYMBOL OBJECT_NAME OBJECT_TYPE TERM_ACC_ID TERM_NAME QUALIFIER EVIDENCE WITH ASPECT REFERENCES CREATED_DATE ASSIGNED_BY MESH_OMIM_ID CURATION_NOTES ORIGINAL_REFERENCE 18337501 GTF2E2 general transcription factor IIE subunit 2 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1320859 W RGD:9068941 20211008 RGD PMID:24120742|REF_RGD_ID:9681721 18337612 WNT9B Wnt family member 9B gene PW:0000008 Wnt signaling pathway ISO RGD:1319983 W RGD:9068941 20211008 RGD 18337612 WNT9B Wnt family member 9B gene PW:0000008 Wnt signaling pathway ISO RGD:1319984 W RGD:9068941 20211008 RGD 18337612 WNT9B Wnt family member 9B gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1319983 W RGD:9068941 20211008 RGD PMID:18765832|REF_RGD_ID:2313743 18337695 NARS1 asparaginyl-tRNA synthetase 1 gene PW:0001417 Canavan disease pathway ISO RGD:1316312 W RGD:9068941 20211008 SMPDB SMP:00175 18337713 RPL29 ribosomal protein L29 gene PW:0000101 translation pathway ISO RGD:737093 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18337713 RPL29 ribosomal protein L29 gene PW:0001066 ribosome biogenesis pathway ISO RGD:737093 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18337963 UBE2M ubiquitin conjugating enzyme E2 M gene PW:0000415 proteasome degradation pathway involving cullin-dependent ubiquitin ligases ISO RGD:1316910 W RGD:9068941 20211008 RGD PMID:15694336|REF_RGD_ID:1559272 18337963 UBE2M ubiquitin conjugating enzyme E2 M gene PW:0000435 neddylation pathway ISO RGD:1316910 W RGD:9068941 20211008 RGD PMID:15694336|REF_RGD_ID:1559272 18337973 CD14 CD14 molecule gene PW:0000020 cardiovascular system disease pathway ISO RGD:1347263 W RGD:9068941 20211008 RGD PMID:15310678|REF_RGD_ID:1580257 18337973 CD14 CD14 molecule gene PW:0000234 innate immune response pathway ISO RGD:1347263 W RGD:9068941 20211008 RGD PMID:15310678|REF_RGD_ID:1580257 18337973 CD14 CD14 molecule gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1347263 W RGD:9068941 20211008 RGD PMID:22119168|REF_RGD_ID:7247704 18338089 GCKR glucokinase regulator gene PW:0000533 glycogen metabolic pathway ISO RGD:2671 W RGD:9068941 20211008 RGD PMID:14627435|REF_RGD_ID:1598592 18338089 GCKR glucokinase regulator gene PW:0000533 glycogen metabolic pathway ISO RGD:69130 W RGD:9068941 20211008 RGD PMID:14627435|REF_RGD_ID:1598592 18338173 POLM DNA polymerase mu gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:1317912 W RGD:9068941 20211008 RGD PMID:20192759|REF_RGD_ID:8662352 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00671 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00431 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00413 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00402 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00686 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00687 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00691 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00408 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00399 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00422 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00426 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00415 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00425 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00423 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00424 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00684 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00393 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00401 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00404 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00688 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00416 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00397 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00409 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00410 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00411 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00412 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00394 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00681 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00395 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002537 lidocaine pharmacokinetics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00620 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00398 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00400 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00677 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00673 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00407 18338229 SCN10A sodium voltage-gated channel alpha subunit 10 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:1349086 W RGD:9068941 20211008 SMPDB SMP:00675 18338306 EIF4E eukaryotic translation initiation factor 4E gene PW:0000180 mTOR signaling pathway ISO RGD:732833 W RGD:9068941 20211008 PID PID:200096 18338306 EIF4E eukaryotic translation initiation factor 4E gene PW:0000580 translation initiation pathway ISO RGD:732833 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18338306 EIF4E eukaryotic translation initiation factor 4E gene PW:0001626 CRM1 export pathway ISO RGD:732833 W RGD:9068941 20211008 RGD PMID:23583578|REF_RGD_ID:9743967 18338409 ACSL6 acyl-CoA synthetase long chain family member 6 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1349836 W RGD:9068941 20211008 RGD PMID:17762044|REF_RGD_ID:2317576 18338434 DGCR8 DGCR8 microprocessor complex subunit gene PW:0000808 microRNA pathway ISO RGD:1314941 W RGD:9068941 20211008 RGD PMID:20661255|REF_RGD_ID:4144851 18338699 STAM signal transducing adaptor molecule gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1320313 W RGD:9068941 20211008 PID PID:200098 18338834 NFKB2 nuclear factor kappa B subunit 2 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1316230 W RGD:9068941 20211008 PID PID:200048 18338834 NFKB2 nuclear factor kappa B subunit 2 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1316230 W RGD:9068941 20211008 RGD PMID:18267068|REF_RGD_ID:2292172 18338834 NFKB2 nuclear factor kappa B subunit 2 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1316230 W RGD:9068941 20211008 PID PID:200045 18338834 NFKB2 nuclear factor kappa B subunit 2 gene PW:0000998 adenosine signaling pathway ISO RGD:1316230 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18338911 HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 gene PW:0001073 spliceosome pathway ISO RGD:1320680 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18338972 SUV39H2 SUV39H2 histone lysine methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1315884 W RGD:9068941 20211008 RGD PMID:22194015|REF_RGD_ID:7242554 18338972 SUV39H2 SUV39H2 histone lysine methyltransferase gene PW:0001338 histone modification pathway ISO RGD:1315884 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18339092 EPN1 epsin 1 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:1342807 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18339119 NFYB nuclear transcription factor Y subunit beta gene PW:0000720 altered p53 signaling pathway ISO RGD:1352074 W RGD:9068941 20211008 RGD PMID:22713868|PMID:23263379|REF_RGD_ID:8663430|REF_RGD_ID:8663431 18339139 KCNB1 potassium voltage-gated channel subfamily B member 1 gene PW:0000674 insulin secretion pathway ISO RGD:2954 W RGD:9068941 20211008 RGD PMID:12830383|REF_RGD_ID:2311121 18339139 KCNB1 potassium voltage-gated channel subfamily B member 1 gene PW:0000674 insulin secretion pathway ISO RGD:732211 W RGD:9068941 20211008 RGD PMID:12830383|REF_RGD_ID:2311121 18339139 KCNB1 potassium voltage-gated channel subfamily B member 1 gene PW:0000674 insulin secretion pathway ISO RGD:732212 W RGD:9068941 20211008 RGD PMID:12830383|REF_RGD_ID:2311121 18339145 L3MBTL1 L3MBTL histone methyl-lysine binding protein 1 gene PW:0001338 histone modification pathway ISO RGD:1344736 W RGD:9068941 20211008 RGD PMID:23642229|REF_RGD_ID:9479074 18339145 L3MBTL1 L3MBTL histone methyl-lysine binding protein 1 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1344736 W RGD:9068941 20211008 RGD PMID:24002223|PMID:24326623|REF_RGD_ID:8661237|REF_RGD_ID:8661242 18339264 FN1 fibronectin 1 gene PW:0000659 syndecan signaling pathway ISO RGD:736627 W RGD:9068941 20211008 PID PID:200134|PID:200192 18339698 BAAT bile acid-CoA:amino acid N-acyltransferase gene PW:0000039 bile acid biosynthetic pathway ISO RGD:735913 W RGD:9068941 20211008 SMPDB SMP:00035 18339698 BAAT bile acid-CoA:amino acid N-acyltransferase gene PW:0001415 Zellweger syndrome pathway ISO RGD:735913 W RGD:9068941 20211008 SMPDB SMP:00316 18339698 BAAT bile acid-CoA:amino acid N-acyltransferase gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:735913 W RGD:9068941 20211008 SMPDB SMP:00315 18339698 BAAT bile acid-CoA:amino acid N-acyltransferase gene PW:0002302 familial hypercholanemia pathway ISO RGD:735913 W RGD:9068941 20211008 SMPDB SMP:00317 18339698 BAAT bile acid-CoA:amino acid N-acyltransferase gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:735913 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18339747 ATP5F1E ATP synthase F1 subunit epsilon gene PW:0000034 electron transport chain pathway ISO RGD:1346801 W RGD:9068941 20211008 SMPDB SMP:00355 18339811 KYNU kynureninase gene PW:0000054 tryptophan metabolic pathway ISO RGD:71061 W RGD:9068941 20211008 RGD PMID:3400092|PMID:6466295|PMID:7236232|REF_RGD_ID:2290312|REF_RGD_ID:2290313|REF_RGD_ID:2303721 18339811 KYNU kynureninase gene PW:0000054 tryptophan metabolic pathway ISO RGD:734173 W RGD:9068941 20211008 SMPDB SMP:00063 18339811 KYNU kynureninase gene PW:0001282 kynurenine metabolic pathway ISO RGD:734173 W RGD:9068941 20211008 RGD PMID:25773161|REF_RGD_ID:11062165 18339842 BBOX1 gamma-butyrobetaine hydroxylase 1 gene PW:0002292 carnitine biosynthetic pathway ISO RGD:732171 W RGD:9068941 20211008 SMPDB SMP:00465 18339899 RPL24 ribosomal protein L24 gene PW:0000101 translation pathway ISO RGD:731426 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18339899 RPL24 ribosomal protein L24 gene PW:0001066 ribosome biogenesis pathway ISO RGD:731426 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18340655 GTF2H4 general transcription factor IIH subunit 4 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1352501 W RGD:9068941 20211008 RGD PMID:21592869|REF_RGD_ID:9681726 18340679 PPP1CC protein phosphatase 1 catalytic subunit gamma gene PW:0000394 dopamine signaling pathway ISO RGD:734001 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18340679 PPP1CC protein phosphatase 1 catalytic subunit gamma gene PW:0000532 glycogen biosynthetic pathway ISO RGD:734001 W RGD:9068941 20211008 RGD PMID:14715909|REF_RGD_ID:2304325 18340679 PPP1CC protein phosphatase 1 catalytic subunit gamma gene PW:0000534 glycogen degradation pathway ISO RGD:734001 W RGD:9068941 20211008 RGD PMID:14715909|REF_RGD_ID:2304325 18340679 PPP1CC protein phosphatase 1 catalytic subunit gamma gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:734001 W RGD:9068941 20211008 PID PID:200196 18340679 PPP1CC protein phosphatase 1 catalytic subunit gamma gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:734001 W RGD:9068941 20211008 RGD PMID:18454172|REF_RGD_ID:7241020 18340833 HCRT hypocretin neuropeptide precursor gene PW:0000583 orexin/hypocretin signaling pathway ISO RGD:2786 W RGD:9068941 20211008 RGD PMID:17299454|REF_RGD_ID:1642016 18340833 HCRT hypocretin neuropeptide precursor gene PW:0000583 orexin/hypocretin signaling pathway ISO RGD:731040 W RGD:9068941 20211008 RGD PMID:17299454|REF_RGD_ID:1642016 18340833 HCRT hypocretin neuropeptide precursor gene PW:0000583 orexin/hypocretin signaling pathway ISO RGD:731041 W RGD:9068941 20211008 RGD PMID:17299454|REF_RGD_ID:1642016 18340833 HCRT hypocretin neuropeptide precursor gene PW:0000585 orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1 ISO RGD:2786 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18340833 HCRT hypocretin neuropeptide precursor gene PW:0000586 orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2 ISO RGD:2786 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18341127 FMO3 flavin containing dimethylaniline monoxygenase 3 gene PW:0000838 tamoxifen pharmacokinetics pathway ISO RGD:734270 W RGD:9068941 20211008 SMPDB SMP:00606 18341127 FMO3 flavin containing dimethylaniline monoxygenase 3 gene PW:0000839 tamoxifen pharmacodynamics pathway ISO RGD:734270 W RGD:9068941 20211008 SMPDB SMP:00471 18341127 FMO3 flavin containing dimethylaniline monoxygenase 3 gene PW:0001449 nicotine pharmacokinetics pathway ISO RGD:734270 W RGD:9068941 20211008 SMPDB SMP:00628 18341127 FMO3 flavin containing dimethylaniline monoxygenase 3 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:734270 W RGD:9068941 20211008 SMPDB SMP:00431 18341148 SPR sepiapterin reductase gene PW:0001612 Segawa syndrome pathway ISO RGD:1346391 W RGD:9068941 20211008 SMPDB SMP:00490 18341148 SPR sepiapterin reductase gene PW:0002105 dopa responsive dystonia pathway ISO RGD:1346391 W RGD:9068941 20211008 SMPDB SMP:00486 18341356 PGM3 phosphoglucomutase 3 gene PW:0000152 amino sugar metabolic pathway ISO RGD:1603410 W RGD:9068941 20211008 SMPDB SMP:00045 18341356 PGM3 phosphoglucomutase 3 gene PW:0000532 glycogen biosynthetic pathway ISO RGD:1603410 W RGD:9068941 20211008 RGD PMID:9549096|REF_RGD_ID:2304188 18341356 PGM3 phosphoglucomutase 3 gene PW:0000534 glycogen degradation pathway ISO RGD:1603410 W RGD:9068941 20211008 RGD PMID:9549096|REF_RGD_ID:2304188 18341356 PGM3 phosphoglucomutase 3 gene PW:0000559 hexosamine biosynthetic pathway ISO RGD:1603410 W RGD:9068941 20211008 RGD PMID:15466941|REF_RGD_ID:1625539 18341356 PGM3 phosphoglucomutase 3 gene PW:0001631 Tay-Sachs disease pathway ISO RGD:1603410 W RGD:9068941 20211008 SMPDB SMP:00390 18341356 PGM3 phosphoglucomutase 3 gene PW:0001702 french type sialuria pathway ISO RGD:1603410 W RGD:9068941 20211008 SMPDB SMP:00216|SMP:00217 18341356 PGM3 phosphoglucomutase 3 gene PW:0002381 sialic acid storage disease pathway ISO RGD:1603410 W RGD:9068941 20211008 SMPDB SMP:00240 18341556 GADD45G growth arrest and DNA damage inducible gamma gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1323436 W RGD:9068941 20211008 PID PID:200018 18341556 GADD45G growth arrest and DNA damage inducible gamma gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1323436 W RGD:9068941 20211008 PID PID:200045 18342078 AHCY adenosylhomocysteinase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:69260 W RGD:9068941 20211008 RGD PMID:11741948|PMID:2292587|REF_RGD_ID:7242932|REF_RGD_ID:730275 18342078 AHCY adenosylhomocysteinase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:731745 W RGD:9068941 20211008 RGD PMID:23073625|REF_RGD_ID:7242425 18342078 AHCY adenosylhomocysteinase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00033 18342078 AHCY adenosylhomocysteinase gene PW:0000133 selenoamino acid metabolic pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00029 18342078 AHCY adenosylhomocysteinase gene PW:0000212 choline metabolic pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00123 18342078 AHCY adenosylhomocysteinase gene PW:0000398 homocysteine metabolic pathway ISO RGD:69260 W RGD:9068941 20211008 RGD PMID:11741948|REF_RGD_ID:730275 18342078 AHCY adenosylhomocysteinase gene PW:0000398 homocysteine metabolic pathway ISO RGD:731745 W RGD:9068941 20211008 RGD PMID:20814827|REF_RGD_ID:7242426 18342078 AHCY adenosylhomocysteinase gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00123 18342078 AHCY adenosylhomocysteinase gene PW:0001841 homocystinuria pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00177 18342078 AHCY adenosylhomocysteinase gene PW:0001868 hypermethioninemia pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00221 18342078 AHCY adenosylhomocysteinase gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00222 18342078 AHCY adenosylhomocysteinase gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00340 18342078 AHCY adenosylhomocysteinase gene PW:0002471 hypermethioninemia pathway ISO RGD:731745 W RGD:9068941 20211008 SMPDB SMP:00341 18342115 TLN1 talin 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1314756 W RGD:9068941 20211008 PID PID:200101 18342115 TLN1 talin 1 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1314756 W RGD:9068941 20211008 RGD PMID:18363565|PMID:23860236|REF_RGD_ID:2300340|REF_RGD_ID:7349373 18342115 TLN1 talin 1 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1550435 W RGD:9068941 20211008 RGD PMID:18363565|REF_RGD_ID:2300340 18342192 HARS2 histidyl-tRNA synthetase 2, mitochondrial gene PW:0000051 histidine metabolic pathway ISO RGD:1352732 W RGD:9068941 20211008 SMPDB SMP:00044 18342192 HARS2 histidyl-tRNA synthetase 2, mitochondrial gene PW:0001978 histidinemia pathway ISO RGD:1352732 W RGD:9068941 20211008 SMPDB SMP:00191 18342225 PEMT phosphatidylethanolamine N-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:3297 W RGD:9068941 20211008 RGD PMID:8344945|REF_RGD_ID:729486 18342225 PEMT phosphatidylethanolamine N-methyltransferase gene PW:0000212 choline metabolic pathway ISO RGD:732310 W RGD:9068941 20211008 SMPDB SMP:00123 18342225 PEMT phosphatidylethanolamine N-methyltransferase gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:732310 W RGD:9068941 20211008 SMPDB SMP:00025 18342225 PEMT phosphatidylethanolamine N-methyltransferase gene PW:0000398 homocysteine metabolic pathway ISO RGD:3297 W RGD:9068941 20211008 RGD PMID:8344945|REF_RGD_ID:729486 18342225 PEMT phosphatidylethanolamine N-methyltransferase gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:732310 W RGD:9068941 20211008 SMPDB SMP:00123 18342502 SH2B3 SH2B adaptor protein 3 gene PW:0000987 erythropoietin signaling pathway ISO RGD:68607 W RGD:9068941 20211008 PID PID:200183 18342625 TRRAP transformation/transcription domain associated protein gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1313479 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18342625 TRRAP transformation/transcription domain associated protein gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1313479 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18342977 IGF1 insulin like growth factor 1 gene PW:0000020 cardiovascular system disease pathway ISO RGD:2868 W RGD:9068941 20211008 RGD PMID:15996002|REF_RGD_ID:1580474 18342977 IGF1 insulin like growth factor 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:2868 W RGD:9068941 20211008 RGD PMID:16083987|REF_RGD_ID:1580473 18342977 IGF1 insulin like growth factor 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:70506 W RGD:9068941 20211008 PID PID:200100 18342977 IGF1 insulin like growth factor 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:70506 W RGD:9068941 20211008 RGD PMID:15862547|PMID:7526037|REF_RGD_ID:12904768|REF_RGD_ID:1626333 18342977 IGF1 insulin like growth factor 1 gene PW:0000510 altered insulin-like growth factor signaling pathway ISO RGD:2868 W RGD:9068941 20211008 RGD PMID:15996002|REF_RGD_ID:1580474 18342977 IGF1 insulin like growth factor 1 gene PW:0000961 ceramide signaling pathway ISO RGD:70506 W RGD:9068941 20211008 PID PID:200119 18342977 IGF1 insulin like growth factor 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:70506 W RGD:9068941 20211008 PID PID:200182 18343082 MDM2 MDM2 proto-oncogene gene PW:0000718 p53 signaling pathway ISO RGD:1313299 W RGD:9068941 20211008 PID PID:200206 18343082 MDM2 MDM2 proto-oncogene gene PW:0000718 p53 signaling pathway ISO RGD:1313299 W RGD:9068941 20211008 RGD PMID:16601750|PMID:19450511|REF_RGD_ID:2316155|REF_RGD_ID:2316156 18343082 MDM2 MDM2 proto-oncogene gene PW:0000720 altered p53 signaling pathway ISO RGD:1313299 W RGD:9068941 20211008 RGD PMID:19165225|PMID:23262034|REF_RGD_ID:2316186|REF_RGD_ID:8663434 18343130 SUFU SUFU negative regulator of hedgehog signaling gene PW:0000122 Hedgehog signaling pathway ISO RGD:1346700 W RGD:9068941 20211008 PID PID:200172 18343130 SUFU SUFU negative regulator of hedgehog signaling gene PW:0000122 Hedgehog signaling pathway ISO RGD:1346700 W RGD:9068941 20211008 RGD PMID:20716670|REF_RGD_ID:5510013 18343157 TIMM9 translocase of inner mitochondrial membrane 9 gene PW:0002138 carrier pathway of mitochondrial protein import ISO RGD:1352655 W RGD:9068941 20211008 RGD PMID:14726512|REF_RGD_ID:10412667 18343157 TIMM9 translocase of inner mitochondrial membrane 9 gene PW:0002140 beta-barrel pathway of mitochondrial protein import ISO RGD:1352655 W RGD:9068941 20211008 RGD PMID:25305573|REF_RGD_ID:10412662 18343302 AMDHD1 amidohydrolase domain containing 1 gene PW:0000051 histidine metabolic pathway ISO RGD:1603900 W RGD:9068941 20211008 SMPDB SMP:00044 18343302 AMDHD1 amidohydrolase domain containing 1 gene PW:0001978 histidinemia pathway ISO RGD:1603900 W RGD:9068941 20211008 SMPDB SMP:00191 18343329 FGFR2 fibroblast growth factor receptor 2 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:2611 W RGD:9068941 20211008 RGD PMID:15292181|REF_RGD_ID:2289848 18343329 FGFR2 fibroblast growth factor receptor 2 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:736865 W RGD:9068941 20211008 PID PID:200220 18343512 PSENEN presenilin enhancer, gamma-secretase subunit gene PW:0000204 Notch signaling pathway ISO RGD:1347919 W RGD:9068941 20211008 PID PID:200015 18343512 PSENEN presenilin enhancer, gamma-secretase subunit gene PW:0000204 Notch signaling pathway ISO RGD:1347919 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18343512 PSENEN presenilin enhancer, gamma-secretase subunit gene PW:0000659 syndecan signaling pathway ISO RGD:1347919 W RGD:9068941 20211008 PID PID:200198 18343693 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:736670 W RGD:9068941 20211008 SMPDB SMP:00025 18343693 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:736670 W RGD:9068941 20211008 SMPDB SMP:00463 18343776 APP amyloid beta precursor protein gene PW:0000658 glypican signaling pathway ISO RGD:736021 W RGD:9068941 20211008 PID PID:200026 18343842 AGTRAP angiotensin II receptor associated protein gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:1359346 W RGD:9068941 20211008 RGD PMID:17875818|REF_RGD_ID:2314353 18343986 DISP1 dispatched RND transporter family member 1 gene PW:0000122 Hedgehog signaling pathway ISO RGD:1317002 W RGD:9068941 20211008 RGD PMID:20635334|REF_RGD_ID:5510026 18344179 CCL2 C-C motif chemokine ligand 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:3645 W RGD:9068941 20211008 RGD PMID:14693680|REF_RGD_ID:1580560 18344179 CCL2 C-C motif chemokine ligand 2 gene PW:0000244 angiotensin II signaling pathway ISO RGD:3645 W RGD:9068941 20211008 RGD PMID:14684844|REF_RGD_ID:1582323 18344179 CCL2 C-C motif chemokine ligand 2 gene PW:0000915 interleukin-23 signaling pathway ISO RGD:731046 W RGD:9068941 20211008 PID PID:200154 18344179 CCL2 C-C motif chemokine ligand 2 gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:731046 W RGD:9068941 20211008 PID PID:200019 18344219 MAPK10 mitogen-activated protein kinase 10 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:733441 W RGD:9068941 20211008 PID PID:200149 18344219 MAPK10 mitogen-activated protein kinase 10 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:3663 W RGD:9068941 20211008 RGD PMID:10051439|PMID:15680699|REF_RGD_ID:2298561|REF_RGD_ID:2298567 18344219 MAPK10 mitogen-activated protein kinase 10 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:733441 W RGD:9068941 20211008 RGD PMID:17306896|REF_RGD_ID:2293875 18344219 MAPK10 mitogen-activated protein kinase 10 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:733441 W RGD:9068941 20211008 PID PID:200020 18344219 MAPK10 mitogen-activated protein kinase 10 gene PW:0000681 FasL mediated signaling pathway ISO RGD:733441 W RGD:9068941 20211008 PID PID:200080 18344289 PPP3R1 protein phosphatase 3 regulatory subunit B, alpha gene PW:0000315 calcineurin signaling pathway ISO RGD:1350432 W RGD:9068941 20211008 RGD PMID:15336966|REF_RGD_ID:1579951 18344289 PPP3R1 protein phosphatase 3 regulatory subunit B, alpha gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1350432 W RGD:9068941 20211008 PID PID:200045 18344428 CDKN1C cyclin dependent kinase inhibitor 1C gene PW:0000088 G1/S transition pathway ISO RGD:1322980 W RGD:9068941 20211008 RGD PMID:10919634|REF_RGD_ID:8694143 18344618 RAB3A RAB3A, member RAS oncogene family gene PW:0000674 insulin secretion pathway ISO RGD:11212 W RGD:9068941 20211008 RGD PMID:19295123|REF_RGD_ID:2311087 18344709 USO1 USO1 vesicle transport factor gene PW:0000387 Arf family mediated signaling pathway ISO RGD:733099 W RGD:9068941 20211008 PID PID:200195 18344822 PEX14 peroxisomal biogenesis factor 14 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:68470 W RGD:9068941 20211008 SMPDB SMP:00052 18344822 PEX14 peroxisomal biogenesis factor 14 gene PW:0002505 adrenoleukodystrophy pathway ISO RGD:68470 W RGD:9068941 20211008 SMPDB SMP:00516 18344822 PEX14 peroxisomal biogenesis factor 14 gene PW:0002506 carnitine-acylcarnitine translocase deficiency ISO RGD:68470 W RGD:9068941 20211008 SMPDB SMP:00517 18344838 SNRPA small nuclear ribonucleoprotein polypeptide A gene PW:0001073 spliceosome pathway ISO RGD:1316600 W RGD:9068941 20211008 RGD PMID:23592432|REF_RGD_ID:9686090 18344933 KDM4C lysine demethylase 4C gene PW:0001338 histone modification pathway ISO RGD:1316776 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18345234 F11 coagulation factor XI gene PW:0000474 coagulation cascade pathway ISO RGD:1309364 W RGD:9068941 20211008 RGD PMID:10048754|REF_RGD_ID:2290183 18345234 F11 coagulation factor XI gene PW:0000474 coagulation cascade pathway ISO RGD:1319673 W RGD:9068941 20211008 RGD PMID:12787532|PMID:26018600|REF_RGD_ID:11342779|REF_RGD_ID:11352277 18345234 F11 coagulation factor XI gene PW:0000731 warfarin pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00268 18345234 F11 coagulation factor XI gene PW:0001600 acenocoumarol pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00269 18345234 F11 coagulation factor XI gene PW:0001637 alteplase pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00280 18345234 F11 coagulation factor XI gene PW:0001655 aminocaproic acid pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00286 18345234 F11 coagulation factor XI gene PW:0001664 anistreplase pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00281 18345234 F11 coagulation factor XI gene PW:0001788 tranexamic acid pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00287 18345234 F11 coagulation factor XI gene PW:0002149 bivalirudin pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00277 18345234 F11 coagulation factor XI gene PW:0002223 aprotinin pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00288 18345234 F11 coagulation factor XI gene PW:0002229 argatroban pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00276 18345234 F11 coagulation factor XI gene PW:0002258 reteplase pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00285 18345234 F11 coagulation factor XI gene PW:0002329 heparin pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00274 18345234 F11 coagulation factor XI gene PW:0002332 enoxaparin pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00272 18345234 F11 coagulation factor XI gene PW:0002437 fondaparinux pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00273 18345234 F11 coagulation factor XI gene PW:0002494 phenindione pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00655 18345234 F11 coagulation factor XI gene PW:0002497 dicoumarol pharmacodynamics pathway ISO RGD:1319673 W RGD:9068941 20211008 SMPDB SMP:00270|SMP:00656 18345352 KIF3A kinesin family member 3A gene PW:0000122 Hedgehog signaling pathway ISO RGD:1352051 W RGD:9068941 20211008 PID PID:200172 18345352 KIF3A kinesin family member 3A gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1352051 W RGD:9068941 20211008 RGD PMID:24613967|REF_RGD_ID:10053654 18345516 CAT catalase gene PW:0000054 tryptophan metabolic pathway ISO RGD:732740 W RGD:9068941 20211008 SMPDB SMP:00063 18345516 CAT catalase gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:732740 W RGD:9068941 20211008 SMPDB SMP:00429 18345679 SLC24A2 solute carrier family 24 member 2 gene PW:0000962 visual phototransduction pathway ISO RGD:730928 W RGD:9068941 20211008 RGD PMID:18690016|REF_RGD_ID:6893550 18345679 SLC24A2 solute carrier family 24 member 2 gene PW:0001139 calcium transport pathway ISO RGD:730928 W RGD:9068941 20211008 RGD PMID:17716241|REF_RGD_ID:7204698 18345679 SLC24A2 solute carrier family 24 member 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:730928 W RGD:9068941 20211008 RGD PMID:17716241|REF_RGD_ID:7204698 18345749 MPHOSPH10 M-phase phosphoprotein 10 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1316939 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18346343 CHRNA1 cholinergic receptor nicotinic alpha 1 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:732599 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18346343 CHRNA1 cholinergic receptor nicotinic alpha 1 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:732600 W RGD:9068941 20211008 RGD PMID:23032192|REF_RGD_ID:8549508 18346622 NOP58 NOP58 ribonucleoprotein gene PW:0001066 ribosome biogenesis pathway ISO RGD:733462 W RGD:9068941 20211008 RGD PMID:22065625|REF_RGD_ID:9999451 18346698 FAU FAU ubiquitin like and ribosomal protein S30 fusion gene PW:0000101 translation pathway ISO RGD:1351680 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18346698 FAU FAU ubiquitin like and ribosomal protein S30 fusion gene PW:0001066 ribosome biogenesis pathway ISO RGD:1351680 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0000031 purine metabolic pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00050 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0000491 vasopressin signaling pathway ISO RGD:736102 W RGD:9068941 20211008 RGD PMID:18431594|REF_RGD_ID:2312656 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:3281 W RGD:9068941 20211008 RGD PMID:11296225|REF_RGD_ID:68716 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:736102 W RGD:9068941 20211008 RGD PMID:17376027|REF_RGD_ID:2312479 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:736102 W RGD:9068941 20211008 RGD PMID:18431594|REF_RGD_ID:2312656 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001590 xanthinuria pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00220 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001591 xanthinuria type I pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00512 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001592 xanthinuria type II pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00513 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00210 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00537 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00203 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00364 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00365 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00428 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002071 dipyridamole pharmacodyamics pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00264 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00427 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00167 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002288 cilostazol pharmacodynamics pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00263 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002294 AICA-ribosuria pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00168 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00430 18346925 LOC103221883 uncharacterized LOC103221883 gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:736102 W RGD:9068941 20211008 SMPDB SMP:00535 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0000962 visual phototransduction pathway ISO RGD:621815 W RGD:9068941 20211008 RGD PMID:12087135|REF_RGD_ID:6893549 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0000962 visual phototransduction pathway ISO RGD:730948 W RGD:9068941 20211008 RGD PMID:12087135|REF_RGD_ID:6893549 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0001139 calcium transport pathway ISO RGD:621815 W RGD:9068941 20211008 RGD PMID:12087135|REF_RGD_ID:6893549 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0001139 calcium transport pathway ISO RGD:730948 W RGD:9068941 20211008 RGD PMID:12087135|REF_RGD_ID:6893549 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:730948 W RGD:9068941 20211008 RGD PMID:22435804|REF_RGD_ID:7204690 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0001495 altered visual phototransduction pathway ISO RGD:730948 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18346986 LOC103246137 cyclic nucleotide gated channel subunit alpha 1 gene PW:0001497 retinitis pigmentosa pathway ISO RGD:730948 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18347130 AKAP9 A-kinase anchoring protein 9 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1349720 W RGD:9068941 20211008 RGD PMID:14715913|PMID:19319965|REF_RGD_ID:2312475|REF_RGD_ID:2312477 18347250 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 gene PW:0002061 mitochondria transport pathway ISO RGD:1351274 W RGD:9068941 20211008 RGD PMID:21936784|PMID:25612908|REF_RGD_ID:10402141|REF_RGD_ID:10402142 18347337 VANGL2 VANGL planar cell polarity protein 2 gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1319788 W RGD:9068941 20211008 RGD PMID:17226800|REF_RGD_ID:2293492 18347496 P2RY12 purinergic receptor P2Y12 gene PW:0001466 clopidogrel pharmacokinetics pathway ISO RGD:1354000 W RGD:9068941 20211008 SMPDB SMP:00610 18347496 P2RY12 purinergic receptor P2Y12 gene PW:0001467 clopidogrel pharmacodynamics pathway ISO RGD:1354000 W RGD:9068941 20211008 SMPDB SMP:00260 18347496 P2RY12 purinergic receptor P2Y12 gene PW:0001732 ticlopidine pharmacokinetics pathway ISO RGD:1354000 W RGD:9068941 20211008 SMPDB SMP:00611 18347496 P2RY12 purinergic receptor P2Y12 gene PW:0001733 ticlopidine pharmacodynamics pathway ISO RGD:1354000 W RGD:9068941 20211008 SMPDB SMP:00261 18347565 ITPK1 inositol-tetrakisphosphate 1-kinase gene PW:0000046 inositol metabolic pathway ISO RGD:1312967 W RGD:9068941 20211008 SMPDB SMP:00011 18347565 ITPK1 inositol-tetrakisphosphate 1-kinase gene PW:0000154 inositol phosphate metabolic pathway ISO RGD:1312967 W RGD:9068941 20211008 SMPDB SMP:00462 18347663 PMS1 PMS1 homolog 1, mismatch repair system component gene PW:0000612 colorectal cancer pathway ISO RGD:1349068 W RGD:9068941 20211008 RGD PMID:11900875|REF_RGD_ID:2306714 18347663 PMS1 PMS1 homolog 1, mismatch repair system component gene PW:0000662 mismatch repair pathway ISO RGD:1349068 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18347663 PMS1 PMS1 homolog 1, mismatch repair system component gene PW:0000668 altered mismatch repair pathway ISO RGD:1349068 W RGD:9068941 20211008 RGD PMID:11900875|REF_RGD_ID:2306714 18347716 GLP1R glucagon like peptide 1 receptor gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:2703 W RGD:9068941 20240829 RGD PMID:10446905|REF_RGD_ID:1598448 18347887 UFD1 ubiquitin recognition factor in ER associated degradation 1 gene PW:0000241 schizophrenia pathway ISO RGD:732948 W RGD:9068941 20211008 RGD PMID:11496370|REF_RGD_ID:1358598 18347906 RPE ribulose-5-phosphate-3-epimerase gene PW:0000045 pentose phosphate pathway ISO RGD:1320609 W RGD:9068941 20211008 SMPDB SMP:00031 18347906 RPE ribulose-5-phosphate-3-epimerase gene PW:0000045 pentose phosphate pathway ISO RGD:1564890 W RGD:9068941 20211008 RGD PMID:2843500|REF_RGD_ID:1599574 18347906 RPE ribulose-5-phosphate-3-epimerase gene PW:0000574 pentose phosphate pathway - non-oxidative phase ISO RGD:1564890 W RGD:9068941 20211008 RGD PMID:12721358|REF_RGD_ID:1641814 18347906 RPE ribulose-5-phosphate-3-epimerase gene PW:0001629 transaldolase deficiency pathway ISO RGD:1320609 W RGD:9068941 20211008 SMPDB SMP:00520 18347906 RPE ribulose-5-phosphate-3-epimerase gene PW:0001704 ribose 5-phosphate isomerase deficiency pathway ISO RGD:1320609 W RGD:9068941 20211008 SMPDB SMP:00519 18348248 PRMT3 protein arginine methyltransferase 3 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1604394 W RGD:9068941 20211008 RGD PMID:21074527|REF_RGD_ID:7242552 18348248 PRMT3 protein arginine methyltransferase 3 gene PW:0000051 histidine metabolic pathway ISO RGD:1604394 W RGD:9068941 20211008 SMPDB SMP:00044 18348248 PRMT3 protein arginine methyltransferase 3 gene PW:0001978 histidinemia pathway ISO RGD:1604394 W RGD:9068941 20211008 SMPDB SMP:00191 18348373 BCHE butyrylcholinesterase gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:732174 W RGD:9068941 20211008 SMPDB SMP:00600 18348373 BCHE butyrylcholinesterase gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:732174 W RGD:9068941 20211008 SMPDB SMP:00433 18348373 BCHE butyrylcholinesterase gene PW:0002559 heroin pharmacokinetics pathway ISO RGD:732174 W RGD:9068941 20211008 SMPDB SMP:00623 18348373 BCHE butyrylcholinesterase gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:732174 W RGD:9068941 20211008 SMPDB SMP:00407 18348418 SF3B4 splicing factor 3b subunit 4 gene PW:0001073 spliceosome pathway ISO RGD:1320131 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18348456 USP16 ubiquitin specific peptidase 16 gene PW:0001338 histone modification pathway ISO RGD:1316236 W RGD:9068941 20211008 RGD PMID:24647359|REF_RGD_ID:9479061 18348456 USP16 ubiquitin specific peptidase 16 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1316236 W RGD:9068941 20211008 RGD PMID:24002223|REF_RGD_ID:8661242 18348507 ADCY10 adenylate cyclase 10 gene PW:0000031 purine metabolic pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00050 18348507 ADCY10 adenylate cyclase 10 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:737484 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18348507 ADCY10 adenylate cyclase 10 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:737485 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18348507 ADCY10 adenylate cyclase 10 gene PW:0001590 xanthinuria pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00220 18348507 ADCY10 adenylate cyclase 10 gene PW:0001591 xanthinuria type I pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00512 18348507 ADCY10 adenylate cyclase 10 gene PW:0001592 xanthinuria type II pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00513 18348507 ADCY10 adenylate cyclase 10 gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00210 18348507 ADCY10 adenylate cyclase 10 gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00537 18348507 ADCY10 adenylate cyclase 10 gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00203 18348507 ADCY10 adenylate cyclase 10 gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00364 18348507 ADCY10 adenylate cyclase 10 gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00365 18348507 ADCY10 adenylate cyclase 10 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00428 18348507 ADCY10 adenylate cyclase 10 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00427 18348507 ADCY10 adenylate cyclase 10 gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00167 18348507 ADCY10 adenylate cyclase 10 gene PW:0002294 AICA-ribosuria pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00168 18348507 ADCY10 adenylate cyclase 10 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00430 18348507 ADCY10 adenylate cyclase 10 gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:737484 W RGD:9068941 20211008 SMPDB SMP:00535 18348577 CASQ1 calsequestrin 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1344349 W RGD:9068941 20211008 RGD PMID:20356453|REF_RGD_ID:7204686 18348621 CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 gene PW:0001962 mitochondrial protein import pathway contributes_to ISO RGD:1312070 W RGD:9068941 20211008 RGD PMID:23109542|REF_RGD_ID:10412671 18348665 STK11 serine/threonine kinase 11 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1308653 W RGD:9068941 20211008 RGD PMID:14511394|PMID:15509864|REF_RGD_ID:1600678|REF_RGD_ID:1600691 18348665 STK11 serine/threonine kinase 11 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1318548 W RGD:9068941 20211008 RGD PMID:15509864|REF_RGD_ID:1600678 18348665 STK11 serine/threonine kinase 11 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1318549 W RGD:9068941 20211008 RGD PMID:15509864|REF_RGD_ID:1600678 18348698 DAAM1 dishevelled associated activator of morphogenesis 1 gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1346826 W RGD:9068941 20211008 RGD PMID:17226800|REF_RGD_ID:2293492 18348698 DAAM1 dishevelled associated activator of morphogenesis 1 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1346826 W RGD:9068941 20211008 PID PID:200020 18349058 CYLD CYLD lysine 63 deubiquitinase gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1319183 W RGD:9068941 20211008 PID PID:200102 18349058 CYLD CYLD lysine 63 deubiquitinase gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1319183 W RGD:9068941 20211008 RGD PMID:21119682|PMID:23312890|REF_RGD_ID:7800734|REF_RGD_ID:7800735 18349058 CYLD CYLD lysine 63 deubiquitinase gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1319183 W RGD:9068941 20211008 PID PID:200031 18349058 CYLD CYLD lysine 63 deubiquitinase gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1319183 W RGD:9068941 20211008 RGD PMID:21119682|PMID:23312890|REF_RGD_ID:7800734|REF_RGD_ID:7800735 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1321367 W RGD:9068941 20211008 PID PID:200018 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1321368 W RGD:9068941 20211008 RGD PMID:12215209|REF_RGD_ID:2296020 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1310457 W RGD:9068941 20211008 RGD PMID:20967881|REF_RGD_ID:5130945 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1321367 W RGD:9068941 20211008 PID PID:200102 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1321367 W RGD:9068941 20211008 RGD PMID:12655295|PMID:23085193|REF_RGD_ID:2292150|REF_RGD_ID:7800730 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1321368 W RGD:9068941 20211008 RGD PMID:12215209|REF_RGD_ID:2296020 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000682 Trail mediated signaling pathway ISO RGD:1321367 W RGD:9068941 20211008 PID PID:200068 18349269 TRAF2 TNF receptor associated factor 2 gene PW:0000961 ceramide signaling pathway ISO RGD:1321367 W RGD:9068941 20211008 PID PID:200119 18349353 RUVBL1 RuvB like AAA ATPase 1 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:68537 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18349507 NOD2 nucleotide binding oligomerization domain containing 2 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1314945 W RGD:9068941 20211008 PID PID:200031 18349507 NOD2 nucleotide binding oligomerization domain containing 2 gene PW:0000817 NOD-like receptor signaling pathway ISO RGD:1306368 W RGD:9068941 20211008 RGD PMID:16973131|REF_RGD_ID:1643119 18349558 DROSHA drosha ribonuclease III gene PW:0000808 microRNA pathway ISO RGD:1605687 W RGD:9068941 20211008 RGD PMID:20661255|REF_RGD_ID:4144851 18349739 OPTN optineurin gene PW:0001842 mitochondrial autophagy pathway ISO RGD:736202 W RGD:9068941 20211008 RGD PMID:25995186|REF_RGD_ID:10401790 18349766 GAST gastrin gene PW:0000769 omeprazole pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00226 18349766 GAST gastrin gene PW:0001836 roxatidine acetate pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00734 18349766 GAST gastrin gene PW:0001845 ranitidine pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00230 18349766 GAST gastrin gene PW:0001848 rabeprazole pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00229 18349766 GAST gastrin gene PW:0001884 pirenzepine pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00246 18349766 GAST gastrin gene PW:0001890 pantoprazole pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00228 18349766 GAST gastrin gene PW:0001906 nizatidine pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00233 18349766 GAST gastrin gene PW:0001965 lansoprazole pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00227 18349766 GAST gastrin gene PW:0002039 famotidine pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00231 18349766 GAST gastrin gene PW:0002112 cimetidine pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00232 18349766 GAST gastrin gene PW:0002184 esomeprazole pharmacodynamics pathway ISO RGD:735826 W RGD:9068941 20211008 SMPDB SMP:00225 18349964 APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 gene PW:0000482 lipoprotein metabolic pathway ISO RGD:736126 W RGD:9068941 20211008 RGD PMID:16011471|REF_RGD_ID:1578416 18350301 CNKSR1 connector enhancer of kinase suppressor of Ras 1 gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:1323565 W RGD:9068941 20211008 RGD PMID:20889352|REF_RGD_ID:5133679 18350301 CNKSR1 connector enhancer of kinase suppressor of Ras 1 gene PW:0000968 interleukin-3 signaling pathway ISO RGD:1323565 W RGD:9068941 20211008 PID PID:200145 18350389 SMOX spermine oxidase gene PW:0000214 polyamine metabolic pathway ISO RGD:1306049 W RGD:9068941 20211008 RGD PMID:15541750|REF_RGD_ID:7244190 18350389 SMOX spermine oxidase gene PW:0000214 polyamine metabolic pathway ISO RGD:1314443 W RGD:9068941 20211008 RGD PMID:13678416|REF_RGD_ID:7244193 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00075 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0000461 cyclooxygenase mediated pathway of arachidonic acid metabolism ISO RGD:731006 W RGD:9068941 20211008 RGD PMID:22679221|PMID:23063076|REF_RGD_ID:8552701|REF_RGD_ID:8552712 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0000762 celecoxib pharmacokinetics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00644 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00096 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0000926 pro-inflammatory cytokine mediated pathway ISO RGD:620349 W RGD:9068941 20211008 RGD MMO:0000166, MMO:0000669, MMO:0000656 PMID:29091898|REF_RGD_ID:15090820 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:731006 W RGD:9068941 20211008 PID PID:200085 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001243 prostanoid biosynthetic pathway ISO RGD:731006 W RGD:9068941 20211008 RGD PMID:22679221|PMID:23063076|REF_RGD_ID:8552701|REF_RGD_ID:8552712 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00590 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00086 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001524 paracetamol drug pathway ISO RGD:731006 W RGD:9068941 20211008 RGD PMID:23719833|REF_RGD_ID:8552695 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001524 paracetamol drug pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00710 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00083 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001665 antipyrine drug pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00692 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00116 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00704 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00706 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00094 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00077 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00120 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00114 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00106 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00109 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00098 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00085 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00084 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00289 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00093 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00696 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00104 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00104 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00601 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00442 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00700 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00709 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00708 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00353 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00705 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00697 18350447 PTGS2 prostaglandin-endoperoxide synthase 2 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:731006 W RGD:9068941 20211008 SMPDB SMP:00698 18350461 APOO apolipoprotein O gene PW:0001962 mitochondrial protein import pathway contributes_to ISO RGD:1603962 W RGD:9068941 20211008 RGD PMID:23109542|REF_RGD_ID:10412671 18350487 LOC103219498 RNA 3'-terminal phosphate cyclase-like protein gene PW:0001066 ribosome biogenesis pathway ISO RGD:1313278 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18350513 PTGIS prostaglandin I2 synthase gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00075 18350513 PTGIS prostaglandin I2 synthase gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00096 18350513 PTGIS prostaglandin I2 synthase gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00086 18350513 PTGIS prostaglandin I2 synthase gene PW:0001524 paracetamol drug pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00710 18350513 PTGIS prostaglandin I2 synthase gene PW:0001534 prostacyclin biosynthetic pathway ISO RGD:3438 W RGD:9068941 20240201 RGD PMID:10073980|PMID:10536678|REF_RGD_ID:401959739|REF_RGD_ID:401960092 18350513 PTGIS prostaglandin I2 synthase gene PW:0001534 prostacyclin biosynthetic pathway ISO RGD:736622 W RGD:9068941 20211008 RGD PMID:22679221|REF_RGD_ID:8552712 18350513 PTGIS prostaglandin I2 synthase gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00083 18350513 PTGIS prostaglandin I2 synthase gene PW:0001665 antipyrine drug pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00692 18350513 PTGIS prostaglandin I2 synthase gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00116 18350513 PTGIS prostaglandin I2 synthase gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00704 18350513 PTGIS prostaglandin I2 synthase gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00706 18350513 PTGIS prostaglandin I2 synthase gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00094 18350513 PTGIS prostaglandin I2 synthase gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00077 18350513 PTGIS prostaglandin I2 synthase gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00120 18350513 PTGIS prostaglandin I2 synthase gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00114 18350513 PTGIS prostaglandin I2 synthase gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00106 18350513 PTGIS prostaglandin I2 synthase gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00109 18350513 PTGIS prostaglandin I2 synthase gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00098 18350513 PTGIS prostaglandin I2 synthase gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00085 18350513 PTGIS prostaglandin I2 synthase gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00084 18350513 PTGIS prostaglandin I2 synthase gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00289 18350513 PTGIS prostaglandin I2 synthase gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00093 18350513 PTGIS prostaglandin I2 synthase gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00696 18350513 PTGIS prostaglandin I2 synthase gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00104 18350513 PTGIS prostaglandin I2 synthase gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00104 18350513 PTGIS prostaglandin I2 synthase gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00700 18350513 PTGIS prostaglandin I2 synthase gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00709 18350513 PTGIS prostaglandin I2 synthase gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00708 18350513 PTGIS prostaglandin I2 synthase gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00353 18350513 PTGIS prostaglandin I2 synthase gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00705 18350513 PTGIS prostaglandin I2 synthase gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00697 18350513 PTGIS prostaglandin I2 synthase gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:736622 W RGD:9068941 20211008 SMPDB SMP:00698 18350687 TIMM10B translocase of inner mitochondrial membrane 10B gene PW:0002138 carrier pathway of mitochondrial protein import ISO RGD:736128 W RGD:9068941 20211008 RGD PMID:14726512|REF_RGD_ID:10412667 18350877 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit gene PW:0001338 histone modification pathway ISO RGD:1313612 W RGD:9068941 20211008 RGD PMID:22663077|REF_RGD_ID:9479053 18350944 RPLP0 ribosomal protein lateral stalk subunit P0 gene PW:0000101 translation pathway ISO RGD:1344368 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18350944 RPLP0 ribosomal protein lateral stalk subunit P0 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1344368 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18350981 TF transferrin gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1342593 W RGD:9068941 20211008 PID PID:200052 18350981 TF transferrin gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1342593 W RGD:9068941 20211008 PID PID:200202 18350981 TF transferrin gene PW:0002631 iron uptake pathway ISO RGD:11406 W RGD:9068941 20211008 RGD PMID:25661197|REF_RGD_ID:11554199 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:1307040 W RGD:9068941 20211008 RGD PMID:9487126|REF_RGD_ID:2293350 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1316000 W RGD:9068941 20211008 PID PID:200149 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1307040 W RGD:9068941 20211203 RGD PMID:17064355|REF_RGD_ID:2298577 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1316000 W RGD:9068941 20211008 RGD PMID:10051439|PMID:17306896|REF_RGD_ID:2293875|REF_RGD_ID:2298561 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1316000 W RGD:9068941 20211008 PID PID:200204 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1316000 W RGD:9068941 20211008 PID PID:200146 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000682 Trail mediated signaling pathway ISO RGD:1316000 W RGD:9068941 20211008 PID PID:200068 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0000961 ceramide signaling pathway ISO RGD:1316000 W RGD:9068941 20211008 PID PID:200119 18351009 MAP2K4 mitogen-activated protein kinase kinase 4 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:1316000 W RGD:9068941 20211008 SMPDB SMP:00358 18351084 ATR ATR serine/threonine kinase gene PW:0000718 p53 signaling pathway ISO RGD:1314047 W RGD:9068941 20211008 PID PID:200206 18351297 POLR1C RNA polymerase I and III subunit C gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1320170 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18351297 POLR1C RNA polymerase I and III subunit C gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1320170 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18351436 CARS1 cysteinyl-tRNA synthetase 1 gene PW:0000049 cysteine metabolic pathway ISO RGD:1321833 W RGD:9068941 20211008 SMPDB SMP:00013 18351436 CARS1 cysteinyl-tRNA synthetase 1 gene PW:0002218 ocular nonnephropathic cystinosis pathway ISO RGD:1321833 W RGD:9068941 20211008 SMPDB SMP:00722 18351436 CARS1 cysteinyl-tRNA synthetase 1 gene PW:0002568 mercaptolactate-cysteine disulfiduria pathway ISO RGD:1321833 W RGD:9068941 20211008 SMPDB SMP:00499 18351752 FZD9 frizzled class receptor 9 gene PW:0000008 Wnt signaling pathway ISO RGD:734068 W RGD:9068941 20211008 RGD 18351814 SNTA1 syntrophin alpha 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00296 18351814 SNTA1 syntrophin alpha 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00379 18351814 SNTA1 syntrophin alpha 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00665 18351814 SNTA1 syntrophin alpha 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00376 18351814 SNTA1 syntrophin alpha 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00375 18351814 SNTA1 syntrophin alpha 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00659 18351814 SNTA1 syntrophin alpha 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00660 18351814 SNTA1 syntrophin alpha 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00323 18351814 SNTA1 syntrophin alpha 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00307 18351814 SNTA1 syntrophin alpha 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00324 18351814 SNTA1 syntrophin alpha 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00380 18351814 SNTA1 syntrophin alpha 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00381 18351814 SNTA1 syntrophin alpha 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00382 18351814 SNTA1 syntrophin alpha 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00366 18351814 SNTA1 syntrophin alpha 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00302 18351814 SNTA1 syntrophin alpha 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00378 18351814 SNTA1 syntrophin alpha 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00332 18351814 SNTA1 syntrophin alpha 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00331 18351814 SNTA1 syntrophin alpha 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00301 18351814 SNTA1 syntrophin alpha 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00325 18351814 SNTA1 syntrophin alpha 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00359 18351814 SNTA1 syntrophin alpha 1 gene PW:0002134 bupranolol drug pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00670 18351814 SNTA1 syntrophin alpha 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00670 18351814 SNTA1 syntrophin alpha 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00300 18351814 SNTA1 syntrophin alpha 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00299 18351814 SNTA1 syntrophin alpha 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00296 18351814 SNTA1 syntrophin alpha 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00298 18351814 SNTA1 syntrophin alpha 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00305 18351814 SNTA1 syntrophin alpha 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00303 18351814 SNTA1 syntrophin alpha 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00306 18351814 SNTA1 syntrophin alpha 1 gene PW:0002297 fosphenytoin pharmacokinetics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00618 18351814 SNTA1 syntrophin alpha 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00326 18351814 SNTA1 syntrophin alpha 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00666 18351814 SNTA1 syntrophin alpha 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00327 18351814 SNTA1 syntrophin alpha 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00329 18351814 SNTA1 syntrophin alpha 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00662 18351814 SNTA1 syntrophin alpha 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00663 18351814 SNTA1 syntrophin alpha 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00328 18351814 SNTA1 syntrophin alpha 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:1316039 W RGD:9068941 20211008 SMPDB SMP:00367 18352438 FSHB follicle stimulating hormone subunit beta gene PW:0001071 follicle-stimulating hormone signaling pathway ISO RGD:69084 W RGD:9068941 20211008 SMPDB SMP:00333 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:731036 W RGD:9068941 20211008 PID PID:200168 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000125 G protein mediated signaling pathway ISO RGD:2062 W RGD:9068941 20211008 RGD PMID:29081032|REF_RGD_ID:13506833 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:2062 W RGD:9068941 20211008 RGD PMID:1403099|REF_RGD_ID:632163 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:16304060|REF_RGD_ID:5133417 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000565 eicosanoid signaling pathway ISO RGD:731036 W RGD:9068941 20211008 PID PID:200082 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000579 somatostatin signaling pathway ISO RGD:2062 W RGD:9068941 20211008 RGD PMID:23073237|REF_RGD_ID:13792788 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000794 epinephrine signaling pathway via adrenergic receptor beta ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:19110970|PMID:19229505|REF_RGD_ID:4140391|REF_RGD_ID:5135529 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000843 acetylcholine signaling pathway via muscarinic acetylcholine receptor ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:23759942|REF_RGD_ID:8549590 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:2062 W RGD:9068941 20211008 RGD PMID:23940634|REF_RGD_ID:13792715 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:19395963|REF_RGD_ID:7207470 18352715 GRK2 G protein-coupled receptor kinase 2 gene PW:0001141 calcium signaling pathway via the calcium-sensing receptor ISO RGD:731036 W RGD:9068941 20211008 RGD PMID:15637145|REF_RGD_ID:7207060 18352740 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1601854 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22960599|REF_RGD_ID:9588243|REF_RGD_ID:9588244 18352825 BRD3 bromodomain containing 3 gene PW:0001338 histone modification pathway ISO RGD:1318974 W RGD:9068941 20211008 RGD PMID:24686119|REF_RGD_ID:9479075 18352999 MAP3K10 mitogen-activated protein kinase kinase kinase 10 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1318115 W RGD:9068941 20211008 PID PID:200018 18352999 MAP3K10 mitogen-activated protein kinase kinase kinase 10 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1318115 W RGD:9068941 20211008 RGD PMID:17306896|REF_RGD_ID:2293875 18353053 CNOT7 CCR4-NOT transcription complex subunit 7 gene PW:0000808 microRNA pathway ISO RGD:1313268 W RGD:9068941 20211008 RGD PMID:23337855|REF_RGD_ID:9850101 18353157 RPL5 ribosomal protein L5 gene PW:0000101 translation pathway ISO RGD:731697 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18353157 RPL5 ribosomal protein L5 gene PW:0000718 p53 signaling pathway ISO RGD:731697 W RGD:9068941 20211008 PID PID:200206 18353157 RPL5 ribosomal protein L5 gene PW:0001066 ribosome biogenesis pathway ISO RGD:731697 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18353173 FKBP4 FKBP prolyl isomerase 4 gene PW:0000507 estrogen signaling pathway ISO RGD:733402 W RGD:9068941 20211008 RGD PMID:18451092|REF_RGD_ID:4892102 18353173 FKBP4 FKBP prolyl isomerase 4 gene PW:0000568 aldosterone signaling pathway ISO RGD:733402 W RGD:9068941 20211008 RGD PMID:21784126|REF_RGD_ID:7421504 18353173 FKBP4 FKBP prolyl isomerase 4 gene PW:0000569 cortisol signaling pathway ISO RGD:733402 W RGD:9068941 20211008 RGD PMID:16610357|REF_RGD_ID:5144125 18353252 PTPRQ protein tyrosine phosphatase receptor type Q gene PW:0001503 auditory mechanotransduction pathway ISO RGD:1345897 W RGD:9068941 20211008 RGD PMID:20624897|REF_RGD_ID:8547669 18353398 CCND1 cyclin D1 gene PW:0000088 G1/S transition pathway ISO RGD:68556 W RGD:9068941 20211008 RGD PMID:10919634|REF_RGD_ID:8694143 18353398 CCND1 cyclin D1 gene PW:0000204 Notch signaling pathway ISO RGD:68556 W RGD:9068941 20211008 PID PID:200015 18353398 CCND1 cyclin D1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:68556 W RGD:9068941 20211008 PID PID:200124 18353819 LSM6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated gene PW:0001073 spliceosome pathway ISO RGD:1345160 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18354038 TLR8 toll like receptor 8 gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1605396 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18354171 DCLRE1C DNA cross-link repair 1C gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:1348428 W RGD:9068941 20211008 RGD PMID:20192759|REF_RGD_ID:8662352 18354461 SGF29 SAGA complex associated factor 29 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1604249 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18354461 SGF29 SAGA complex associated factor 29 gene PW:0001338 histone modification pathway ISO RGD:1604249 W RGD:9068941 20211008 RGD PMID:23642229|PMID:24035451|REF_RGD_ID:9479074|REF_RGD_ID:9479148 18354531 ADRA1B adrenoceptor alpha 1B gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:733119 W RGD:9068941 20211008 RGD PMID:11454900|REF_RGD_ID:1559318 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00133 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00132 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00134 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001880 iminoglycinuria pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00193 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00105 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0001977 Hartnup disease pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00189 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00100 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00115 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00097 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00122 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00088 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00078 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00090 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002214 cystinuria pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00723 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00118 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00135 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00121 18354673 SCNN1A sodium channel epithelial 1 subunit alpha gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:736324 W RGD:9068941 20211008 SMPDB SMP:00108 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0000050 arginine and proline metabolic pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00020 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0001807 gyrate atrophy pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00363 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0001931 hyperprolinemia type I pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00361 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0001932 hyperprolinemia type II pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00360 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0002181 prolidase deficiency pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00207 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0002359 AGAT deficiency pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18355058 PYCR2 pyrroline-5-carboxylate reductase 2 gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:1320768 W RGD:9068941 20211008 SMPDB SMP:00506 18355083 RFK riboflavin kinase gene PW:0000137 riboflavin metabolic pathway ISO RGD:1313443 W RGD:9068941 20211008 SMPDB SMP:00070 18355139 AP2A2 adaptor related protein complex 2 subunit alpha 2 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:735567 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18355267 CTSD cathepsin D gene PW:0000961 ceramide signaling pathway ISO RGD:1351014 W RGD:9068941 20211008 PID PID:200119 18355267 CTSD cathepsin D gene PW:0002401 chaperone mediated autophagy pathway ISO RGD:1351014 W RGD:9068941 20211008 RGD PMID:24323530|PMID:25766616|REF_RGD_ID:10755729|REF_RGD_ID:10755730 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00072 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0000050 arginine and proline metabolic pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00020 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0001807 gyrate atrophy pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00363 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0001931 hyperprolinemia type I pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00361 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0001932 hyperprolinemia type II pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00360 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0001979 homocarnosinosis pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00385 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0002181 prolidase deficiency pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00207 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00136 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0002359 AGAT deficiency pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18355306 ALDH4A1 aldehyde dehydrogenase 4 family member A1 gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:1346272 W RGD:9068941 20211008 SMPDB SMP:00506 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0000141 retinol metabolic pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00074 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00648 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00600 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00433 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00622 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00406 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00590 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00086 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00640 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00336 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00327 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00601 18355415 DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:1316536 W RGD:9068941 20211008 SMPDB SMP:00442 18355455 TIMM21 translocase of inner mitochondrial membrane 21 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1351951 W RGD:9068941 20211008 RGD PMID:25542066|PMID:25633533|REF_RGD_ID:10412658|REF_RGD_ID:10412659 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0000064 propanoate metabolic pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00016 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00032 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001778 propionic acidemia pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00236 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00384 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001810 methylmalonic acidemia pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00200 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001811 methylmalonic aciduria, cobalamin-related pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00201 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001870 maple syrup urine disease pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00199 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001874 isovaleric acidemia pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00523 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00139 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00140 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0002289 malonic aciduria pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00198|SMP:00502 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00138 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18355860 PCCA propionyl-CoA carboxylase subunit alpha gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:736733 W RGD:9068941 20211008 SMPDB SMP:00237 18356182 CAV3 caveolin 3 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1344208 W RGD:9068941 20211008 PID PID:200162 18356254 MIOS meiosis regulator for oocyte development gene PW:0000180 mTOR signaling pathway ISO RGD:1601868 W RGD:9068941 20211008 RGD PMID:24698685|REF_RGD_ID:11535043 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0000141 retinol metabolic pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00074 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00648 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00600 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00433 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00622 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00406 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00590 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00086 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00640 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00336 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00327 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00601 18356289 PDIA4 protein disulfide isomerase family A member 4 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:1605716 W RGD:9068941 20211008 SMPDB SMP:00442 18356368 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 gene PW:0001962 mitochondrial protein import pathway contributes_to ISO RGD:1321163 W RGD:9068941 20211008 RGD PMID:23109542|REF_RGD_ID:10412671 18356385 HSCB HscB mitochondrial iron-sulfur cluster cochaperone gene PW:0002635 mitochondrial iron-sulfur cluster protein biogenesis pathway ISO RGD:1602295 W RGD:9068941 20211008 RGD PMID:25245479|REF_RGD_ID:11554190 18356521 RPL39 ribosomal protein L39 gene PW:0000101 translation pathway ISO RGD:735612 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18356521 RPL39 ribosomal protein L39 gene PW:0001066 ribosome biogenesis pathway ISO RGD:735612 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18356523 FSHR follicle stimulating hormone receptor gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:735571 W RGD:9068941 20211008 SMPDB SMP:00322 18356523 FSHR follicle stimulating hormone receptor gene PW:0001071 follicle-stimulating hormone signaling pathway ISO RGD:735571 W RGD:9068941 20211008 SMPDB SMP:00333 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200188 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:731929 W RGD:9068941 20211008 RGD PMID:17658244|REF_RGD_ID:2298729 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200149 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:731929 W RGD:9068941 20211008 PID PID:200059|PID:200142|PID:200204 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000388 Reelin signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200062 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000388 Reelin signaling pathway ISO RGD:731930 W RGD:9068941 20211008 RGD PMID:12778121|REF_RGD_ID:2324970 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000390 altered Reelin signaling pathway ISO RGD:731930 W RGD:9068941 20211008 RGD PMID:12778121|REF_RGD_ID:2324970 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000565 eicosanoid signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200082 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000658 glypican signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200026 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000659 syndecan signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200198 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000840 protein kinase C (PKC) signaling pathway ISO RGD:731929 W RGD:9068941 20211008 RGD PMID:15380937|REF_RGD_ID:5131492 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000907 interleukin-2 signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200098 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200116 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0000992 E-cadherin signaling pathway ISO RGD:731929 W RGD:9068941 20211008 PID PID:200147 18356632 FYN FYN proto-oncogene, Src family tyrosine kinase gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:731929 W RGD:9068941 20211008 SMPDB SMP:00358 18356725 ATRN attractin gene PW:0000365 melanocortin system pathway ISO RGD:69118 W RGD:9068941 20211008 RGD PMID:20654690|REF_RGD_ID:5144214 18356925 APLF aprataxin and PNKP like factor gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:1344091 W RGD:9068941 20211008 RGD PMID:20192759|REF_RGD_ID:8662352 18356925 APLF aprataxin and PNKP like factor gene PW:0001338 histone modification pathway ISO RGD:1344091 W RGD:9068941 20211008 RGD PMID:23288364|REF_RGD_ID:9068945 18356925 APLF aprataxin and PNKP like factor gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1344091 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0000039 bile acid biosynthetic pathway ISO RGD:1346613 W RGD:9068941 20211008 SMPDB SMP:00035 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0000498 reverse cholesterol transport pathway ISO RGD:1346613 W RGD:9068941 20211008 RGD PMID:16258026|REF_RGD_ID:1600654 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0001093 bile acid signaling pathway ISO RGD:1346613 W RGD:9068941 20211008 RGD PMID:28774887|REF_RGD_ID:15045601 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0001415 Zellweger syndrome pathway ISO RGD:1346613 W RGD:9068941 20211008 SMPDB SMP:00316 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:1346613 W RGD:9068941 20211008 SMPDB SMP:00315 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0002302 familial hypercholanemia pathway ISO RGD:1346613 W RGD:9068941 20211008 SMPDB SMP:00317 18357517 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:1346613 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18357549 SRSF2 serine and arginine rich splicing factor 2 gene PW:0001073 spliceosome pathway ISO RGD:1343626 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18357857 CRX cone-rod homeobox gene PW:0001497 retinitis pigmentosa pathway ISO RGD:733182 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18357878 POLR2G RNA polymerase II subunit G gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:733856 W RGD:9068941 20211008 RGD PMID:22960599|REF_RGD_ID:9588243 18357982 NGEF neuronal guanine nucleotide exchange factor gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1319181 W RGD:9068941 20211008 PID PID:200142 18358006 SH2B2 SH2B adaptor protein 2 gene PW:0000143 insulin signaling pathway ISO RGD:736917 W RGD:9068941 20211008 PID PID:200014 18358006 SH2B2 SH2B adaptor protein 2 gene PW:0000143 insulin signaling pathway ISO RGD:736917 W RGD:9068941 20211008 RGD PMID:17347799|REF_RGD_ID:1625124 18358133 FCF1 FCF1 rRNA-processing protein gene PW:0001066 ribosome biogenesis pathway ISO RGD:1322068 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18358148 IL1RAP interleukin 1 receptor accessory protein gene PW:0000883 interleukin-1 signaling pathway ISO RGD:732294 W RGD:9068941 20211008 RGD PMID:20081871|REF_RGD_ID:5490209 18358225 RPL10 ribosomal protein L10 gene PW:0000101 translation pathway ISO RGD:1350175 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18358225 RPL10 ribosomal protein L10 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1350175 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18358319 BCL2L11 BCL2 like 11 gene PW:0000104 intrinsic apoptotic pathway ISO RGD:734299 W RGD:9068941 20211008 RGD PMID:19641503|REF_RGD_ID:2314029 18358351 PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 gene PW:0001647 sulfite oxidase deficiency pathway ISO RGD:1315952 W RGD:9068941 20211008 SMPDB SMP:00532 18358378 SLC28A2 solute carrier family 28 member 2 gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:732572 W RGD:9068941 20211008 SMPDB SMP:00609 18358378 SLC28A2 solute carrier family 28 member 2 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:732572 W RGD:9068941 20211008 SMPDB SMP:00428 18358378 SLC28A2 solute carrier family 28 member 2 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:732572 W RGD:9068941 20211008 SMPDB SMP:00427 18358378 SLC28A2 solute carrier family 28 member 2 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:732572 W RGD:9068941 20211008 SMPDB SMP:00430 18358604 BDNF brain derived neurotrophic factor gene PW:0000572 brain-derived neurotrophic factor signaling pathway ISO RGD:731027 W RGD:9068941 20211008 RGD PMID:23670594|REF_RGD_ID:11062158 18358616 PRDM9 PR/SET domain 9 gene PW:0001338 histone modification pathway ISO RGD:1349245 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18358919 PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 gene PW:0000388 Reelin signaling pathway ISO RGD:732943 W RGD:9068941 20211008 RGD PMID:17330141|REF_RGD_ID:4107040 18358919 PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 gene PW:0000390 altered Reelin signaling pathway ISO RGD:732943 W RGD:9068941 20211008 RGD PMID:17330141|REF_RGD_ID:4107040 18359171 EPHA6 EPH receptor A6 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1605546 W RGD:9068941 20211008 PID PID:200142 18359369 CRADD CASP2 and RIPK1 domain containing adaptor with death domain gene PW:0000961 ceramide signaling pathway ISO RGD:1322237 W RGD:9068941 20211008 PID PID:200119 18359553 GP9 glycoprotein IX platelet gene PW:0000508 platelet aggregation pathway ISO RGD:1351167 W RGD:9068941 20211008 RGD PMID:11487006|REF_RGD_ID:1580446 18359609 EFNB2 ephrin B2 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1319867 W RGD:9068941 20211008 PID PID:200052|PID:200204 18359618 LRP1 LDL receptor related protein 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1316786 W RGD:9068941 20211008 PID PID:200149 18359711 INO80C INO80 complex subunit C gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1320959 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18359790 PRPF18 pre-mRNA processing factor 18 gene PW:0001073 spliceosome pathway ISO RGD:731692 W RGD:9068941 20211008 RGD PMID:24452469|REF_RGD_ID:9686092 18360144 NEDD4 NEDD4 E3 ubiquitin protein ligase gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:736612 W RGD:9068941 20211008 PID PID:200188 18360185 ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1342953 W RGD:9068941 20211008 SMPDB SMP:00034 18360185 ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 gene PW:0001454 Gaucher's disease pathway ISO RGD:1342953 W RGD:9068941 20211008 SMPDB SMP:00349 18360185 ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 gene PW:0002021 Krabbe disease pathway ISO RGD:1342953 W RGD:9068941 20211008 SMPDB SMP:00348 18360185 ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 gene PW:0002103 Fabry disease pathway ISO RGD:1342953 W RGD:9068941 20211008 SMPDB SMP:00525 18360185 ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1342953 W RGD:9068941 20211008 SMPDB SMP:00347 18360295 ADCY5 adenylate cyclase 5 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:71014 W RGD:9068941 20211008 RGD PMID:17010343|REF_RGD_ID:2315004 18360295 ADCY5 adenylate cyclase 5 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:736882 W RGD:9068941 20211008 RGD PMID:18948702|PMID:26468202|REF_RGD_ID:11041137|REF_RGD_ID:2312469 18360295 ADCY5 adenylate cyclase 5 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:736883 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18360295 ADCY5 adenylate cyclase 5 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:736882 W RGD:9068941 20211008 RGD PMID:26468202|REF_RGD_ID:11041137 18360295 ADCY5 adenylate cyclase 5 gene PW:0000506 endothelin signaling pathway ISO RGD:736882 W RGD:9068941 20211008 PID PID:200005 18360295 ADCY5 adenylate cyclase 5 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:736882 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18360295 ADCY5 adenylate cyclase 5 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:736883 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18360295 ADCY5 adenylate cyclase 5 gene PW:0000676 glucagon signaling pathway ISO RGD:71014 W RGD:9068941 20211008 RGD PMID:10894801|PMID:17010343|REF_RGD_ID:2315004|REF_RGD_ID:2315006 18360295 ADCY5 adenylate cyclase 5 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:736882 W RGD:9068941 20211008 RGD PMID:26468202|REF_RGD_ID:11041137 18360295 ADCY5 adenylate cyclase 5 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:736882 W RGD:9068941 20211008 RGD PMID:26468202|REF_RGD_ID:11041137 18360320 HEATR1 HEAT repeat containing 1 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1605668 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18360404 CTDSP2 CTD small phosphatase 2 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1342553 W RGD:9068941 20211008 PID PID:200144 18360440 SGPP1 sphingosine-1-phosphate phosphatase 1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:1343984 W RGD:9068941 20211008 PID PID:200123 18360511 ELAC2 elaC ribonuclease Z 2 gene PW:0001573 tRNA maturation pathway ISO RGD:1342597 W RGD:9068941 20211008 RGD PMID:21572561|REF_RGD_ID:9685334 18360550 RFC2 replication factor C subunit 2 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1348076 W RGD:9068941 20211008 RGD PMID:23545418|REF_RGD_ID:7246932 18360550 RFC2 replication factor C subunit 2 gene PW:0000662 mismatch repair pathway ISO RGD:1348076 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18360643 RAPGEF2 Rap guanine nucleotide exchange factor 2 gene PW:0000998 adenosine signaling pathway ISO RGD:1315047 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18360959 SRCAP Snf2 related CREBBP activator protein gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1606024 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18361099 MORF4L2 mortality factor 4 like 2 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1347861 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18361139 RPS18 ribosomal protein S18 gene PW:0000101 translation pathway ISO RGD:1342484 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18361139 RPS18 ribosomal protein S18 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1342484 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|PMID:25346433|REF_RGD_ID:10002730|REF_RGD_ID:10002762|REF_RGD_ID:9999448 18361266 PRKG1 protein kinase cGMP-dependent 1 gene PW:0000565 eicosanoid signaling pathway ISO RGD:1322442 W RGD:9068941 20211008 PID PID:200082 18361754 POLR3GL RNA polymerase III subunit GL gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1353647 W RGD:9068941 20211008 RGD PMID:20890107|REF_RGD_ID:9685218 18361804 CPSF4 cleavage and polyadenylation specific factor 4 gene PW:0001332 RNA polymerase II transcription termination pathway ISO RGD:736724 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18361804 CPSF4 cleavage and polyadenylation specific factor 4 gene PW:0001579 3'-end pre-mRNA processing pathway ISO RGD:736724 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18361872 F3 coagulation factor III, tissue factor gene PW:0000474 coagulation cascade pathway ISO RGD:737354 W RGD:9068941 20211008 RGD PMID:12787532|PMID:26018600|REF_RGD_ID:11342779|REF_RGD_ID:11352277 18361872 F3 coagulation factor III, tissue factor gene PW:0000731 warfarin pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00268 18361872 F3 coagulation factor III, tissue factor gene PW:0001600 acenocoumarol pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00269 18361872 F3 coagulation factor III, tissue factor gene PW:0001637 alteplase pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00280 18361872 F3 coagulation factor III, tissue factor gene PW:0001655 aminocaproic acid pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00286 18361872 F3 coagulation factor III, tissue factor gene PW:0001664 anistreplase pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00281 18361872 F3 coagulation factor III, tissue factor gene PW:0001788 tranexamic acid pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00287 18361872 F3 coagulation factor III, tissue factor gene PW:0002149 bivalirudin pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00277 18361872 F3 coagulation factor III, tissue factor gene PW:0002223 aprotinin pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00288 18361872 F3 coagulation factor III, tissue factor gene PW:0002229 argatroban pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00276 18361872 F3 coagulation factor III, tissue factor gene PW:0002258 reteplase pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00285 18361872 F3 coagulation factor III, tissue factor gene PW:0002329 heparin pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00274 18361872 F3 coagulation factor III, tissue factor gene PW:0002332 enoxaparin pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00272 18361872 F3 coagulation factor III, tissue factor gene PW:0002437 fondaparinux pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00273 18361872 F3 coagulation factor III, tissue factor gene PW:0002494 phenindione pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00655 18361872 F3 coagulation factor III, tissue factor gene PW:0002497 dicoumarol pharmacodynamics pathway ISO RGD:737354 W RGD:9068941 20211008 SMPDB SMP:00270|SMP:00656 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:736074 W RGD:9068941 20211008 RGD PMID:16876788|REF_RGD_ID:2316857 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00023 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0000728 statin pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0001586 Wolman disease pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00389 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0001812 mevalonic aciduria pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00112 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0001933 hypercholesterolemia pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00209 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00079 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002106 desmosterolosis pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00386 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00095 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00117 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00107 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00508 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00387 18361979 MVD mevalonate diphosphate decarboxylase gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:736074 W RGD:9068941 20211008 SMPDB SMP:00388 18362204 EHMT2 euchromatic histone lysine methyltransferase 2 gene PW:0001338 histone modification pathway ISO RGD:1605700 W RGD:9068941 20211008 RGD PMID:23200123|PMID:23642229|REF_RGD_ID:7242632|REF_RGD_ID:9479074 18362294 SNTB2 syntrophin beta 2 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00296 18362294 SNTB2 syntrophin beta 2 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00379 18362294 SNTB2 syntrophin beta 2 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00665 18362294 SNTB2 syntrophin beta 2 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00376 18362294 SNTB2 syntrophin beta 2 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00375 18362294 SNTB2 syntrophin beta 2 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00659 18362294 SNTB2 syntrophin beta 2 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00660 18362294 SNTB2 syntrophin beta 2 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00323 18362294 SNTB2 syntrophin beta 2 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00307 18362294 SNTB2 syntrophin beta 2 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00324 18362294 SNTB2 syntrophin beta 2 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00380 18362294 SNTB2 syntrophin beta 2 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00381 18362294 SNTB2 syntrophin beta 2 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00382 18362294 SNTB2 syntrophin beta 2 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00366 18362294 SNTB2 syntrophin beta 2 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00302 18362294 SNTB2 syntrophin beta 2 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00378 18362294 SNTB2 syntrophin beta 2 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00332 18362294 SNTB2 syntrophin beta 2 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00331 18362294 SNTB2 syntrophin beta 2 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00301 18362294 SNTB2 syntrophin beta 2 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00325 18362294 SNTB2 syntrophin beta 2 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00359 18362294 SNTB2 syntrophin beta 2 gene PW:0002134 bupranolol drug pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00670 18362294 SNTB2 syntrophin beta 2 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00670 18362294 SNTB2 syntrophin beta 2 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00300 18362294 SNTB2 syntrophin beta 2 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00299 18362294 SNTB2 syntrophin beta 2 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00296 18362294 SNTB2 syntrophin beta 2 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00298 18362294 SNTB2 syntrophin beta 2 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00305 18362294 SNTB2 syntrophin beta 2 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00303 18362294 SNTB2 syntrophin beta 2 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00306 18362294 SNTB2 syntrophin beta 2 gene PW:0002297 fosphenytoin pharmacokinetics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00618 18362294 SNTB2 syntrophin beta 2 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00326 18362294 SNTB2 syntrophin beta 2 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00666 18362294 SNTB2 syntrophin beta 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00327 18362294 SNTB2 syntrophin beta 2 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00329 18362294 SNTB2 syntrophin beta 2 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00662 18362294 SNTB2 syntrophin beta 2 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00663 18362294 SNTB2 syntrophin beta 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00328 18362294 SNTB2 syntrophin beta 2 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:1318541 W RGD:9068941 20211008 SMPDB SMP:00367 18362334 POLR3A RNA polymerase III subunit A gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1351863 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18362681 ATP7A ATPase copper transporting alpha gene PW:0001508 cisplatin drug pathway ISO RGD:10216 W RGD:9068941 20211008 RGD PMID:22796517|REF_RGD_ID:8548473 18362843 ATP2B2 ATPase plasma membrane Ca2+ transporting 2 gene PW:0001139 calcium transport pathway ISO RGD:736839 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18362843 ATP2B2 ATPase plasma membrane Ca2+ transporting 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:736839 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18362931 TH tyrosine hydroxylase gene PW:0000802 dopamine biosynthetic pathway ISO RGD:733897 W RGD:9068941 20211008 RGD PMID:19342614|REF_RGD_ID:4139904 18362931 TH tyrosine hydroxylase gene PW:0000803 epinephrine biosynthetic pathway ISO RGD:733897 W RGD:9068941 20211008 RGD PMID:19342614|REF_RGD_ID:4139904 18362931 TH tyrosine hydroxylase gene PW:0000804 norepinephrine biosynthetic pathway ISO RGD:733897 W RGD:9068941 20211008 RGD PMID:19342614|REF_RGD_ID:4139904 18362931 TH tyrosine hydroxylase gene PW:0001235 catecholamine biosynthetic pathway ISO RGD:733897 W RGD:9068941 20211008 SMPDB SMP:00012 18362931 TH tyrosine hydroxylase gene PW:0002324 aromatic L-amino acid decarboxylase deficiency pathway ISO RGD:733897 W RGD:9068941 20211008 SMPDB SMP:00170 18363030 SPCS1 signal peptidase complex subunit 1 gene PW:0000139 biotin metabolic pathway ISO RGD:1346470 W RGD:9068941 20211008 SMPDB SMP:00066 18363030 SPCS1 signal peptidase complex subunit 1 gene PW:0002254 biotinidase deficiency pathway ISO RGD:1346470 W RGD:9068941 20211008 SMPDB SMP:00174 18363030 SPCS1 signal peptidase complex subunit 1 gene PW:0002255 holocarboxylase synthetase deficiency pathway ISO RGD:1346470 W RGD:9068941 20211008 SMPDB SMP:00564 18363101 S100G S100 calcium binding protein G gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1344914 W RGD:9068941 20211008 RGD PMID:20943758|REF_RGD_ID:7204685 18363151 MRAP melanocortin 2 receptor accessory protein gene PW:0000365 melanocortin system pathway ISO RGD:1603024 W RGD:9068941 20211008 RGD PMID:20654690|REF_RGD_ID:5144214 18363180 TOMM5 translocase of outer mitochondrial membrane 5 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1347873 W RGD:9068941 20211008 RGD PMID:25542066|PMID:25633533|REF_RGD_ID:10412658|REF_RGD_ID:10412659 18363180 TOMM5 translocase of outer mitochondrial membrane 5 gene PW:0002138 carrier pathway of mitochondrial protein import ISO RGD:1347873 W RGD:9068941 20211008 RGD PMID:25980382|REF_RGD_ID:10412661 18363180 TOMM5 translocase of outer mitochondrial membrane 5 gene PW:0002140 beta-barrel pathway of mitochondrial protein import ISO RGD:1347873 W RGD:9068941 20211008 RGD PMID:25305573|REF_RGD_ID:10412662 18363277 TET1 tet methylcytosine dioxygenase 1 gene PW:0001340 DNA modification pathway ISO RGD:1322209 W RGD:9068941 20211008 RGD PMID:22770212|PMID:24825349|REF_RGD_ID:8695943|REF_RGD_ID:8695944 18363367 HLCS holocarboxylase synthetase gene PW:0000139 biotin metabolic pathway ISO RGD:1320489 W RGD:9068941 20211008 SMPDB SMP:00066 18363367 HLCS holocarboxylase synthetase gene PW:0002254 biotinidase deficiency pathway ISO RGD:1320489 W RGD:9068941 20211008 SMPDB SMP:00174 18363367 HLCS holocarboxylase synthetase gene PW:0002255 holocarboxylase synthetase deficiency pathway ISO RGD:1320489 W RGD:9068941 20211008 SMPDB SMP:00564 18363424 DAPK1 death associated protein kinase 1 gene PW:0000896 type II interferon signaling pathway ISO RGD:1323186 W RGD:9068941 20211008 PID PID:200129 18363491 KYAT3 kynurenine aminotransferase 3 gene PW:0001282 kynurenine metabolic pathway ISO RGD:1359262 W RGD:9068941 20211008 RGD PMID:19826765|REF_RGD_ID:11081066 18363491 KYAT3 kynurenine aminotransferase 3 gene PW:0001282 kynurenine metabolic pathway ISO RGD:1606260 W RGD:9068941 20211008 RGD PMID:19826765|REF_RGD_ID:11081066 18363491 KYAT3 kynurenine aminotransferase 3 gene PW:0001282 kynurenine metabolic pathway ISO RGD:1614927 W RGD:9068941 20211008 RGD PMID:19826765|REF_RGD_ID:11081066 18363516 DIAPH1 diaphanous related formin 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1321771 W RGD:9068941 20211008 PID PID:200182 18363814 ADCY8 adenylate cyclase 8 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:733733 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18363814 ADCY8 adenylate cyclase 8 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:736586 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18363814 ADCY8 adenylate cyclase 8 gene PW:0000506 endothelin signaling pathway ISO RGD:733733 W RGD:9068941 20211008 PID PID:200005 18363814 ADCY8 adenylate cyclase 8 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:733733 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18363814 ADCY8 adenylate cyclase 8 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:736586 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18363849 SMS spermine synthase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1345734 W RGD:9068941 20211008 RGD PMID:23073625|REF_RGD_ID:7242425 18363849 SMS spermine synthase gene PW:0000214 polyamine metabolic pathway ISO RGD:1345734 W RGD:9068941 20211008 RGD PMID:13678416|REF_RGD_ID:7244193 18363849 SMS spermine synthase gene PW:0000216 spermine metabolic pathway ISO RGD:1345734 W RGD:9068941 20211008 RGD PMID:23073625|REF_RGD_ID:7242425 18363849 SMS spermine synthase gene PW:0000216 spermine metabolic pathway ISO RGD:1345734 W RGD:9068941 20211008 SMPDB SMP:00445 18363849 SMS spermine synthase gene PW:0000216 spermine metabolic pathway ISO RGD:1564826 W RGD:9068941 20211008 RGD PMID:2292587|REF_RGD_ID:7242932 18363849 SMS spermine synthase gene PW:0000396 spermidine metabolic pathway ISO RGD:1345734 W RGD:9068941 20211008 SMPDB SMP:00445 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1352615 W RGD:9068941 20211008 PID PID:200036|PID:200202 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0000729 statin pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 RGD PMID:17353665|REF_RGD_ID:2316977 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0000870 gefitinib pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 RGD PMID:19733976|REF_RGD_ID:5135288 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0000874 erlotinib pharmacodynamics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00472 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00600 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00433 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001431 lamivudine pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00649 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 RGD PMID:23462933|REF_RGD_ID:8552693 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00640 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1551496 W RGD:9068941 20211008 RGD PMID:23462933|REF_RGD_ID:8552693 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:631345 W RGD:9068941 20211008 RGD PMID:23462933|REF_RGD_ID:8552693 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 RGD PMID:21048526|REF_RGD_ID:10395261 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00650 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001610 tyrosinemia type III pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00434 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0001770 docetaxel pharmacodynamics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00435 18363937 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) gene PW:0002508 mycophenolic acid pharmacokinetics pathway ISO RGD:1352615 W RGD:9068941 20211008 SMPDB SMP:00652 18364001 MAGOHB mago homolog B, exon junction complex subunit gene PW:0001073 spliceosome pathway ISO RGD:1602707 W RGD:9068941 20211008 RGD PMID:15145352|REF_RGD_ID:9686404 18364025 COL16A1 collagen type XVI alpha 1 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1322191 W RGD:9068941 20211008 PID PID:200156 18364162 DDB2 damage specific DNA binding protein 2 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1320906 W RGD:9068941 20211008 RGD PMID:22572993|REF_RGD_ID:7246920 18364273 RPP40 ribonuclease P/MRP subunit p40 gene PW:0001573 tRNA maturation pathway ISO RGD:1321008 W RGD:9068941 20211008 RGD PMID:19931535|REF_RGD_ID:9685326 18364309 EPHX1 epoxide hydrolase 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:736560 W RGD:9068941 20211008 SMPDB SMP:00327 18364309 EPHX1 epoxide hydrolase 1 gene PW:0002464 carbamazepine pharmacokinetics pathway ISO RGD:736560 W RGD:9068941 20211008 SMPDB SMP:00634 18364797 HHIP hedgehog interacting protein gene PW:0000122 Hedgehog signaling pathway ISO RGD:1354359 W RGD:9068941 20211008 PID PID:200168 18364797 HHIP hedgehog interacting protein gene PW:0000122 Hedgehog signaling pathway ISO RGD:1354359 W RGD:9068941 20211008 RGD PMID:20844013|REF_RGD_ID:5510025 18364942 GNMT glycine N-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:2719 W RGD:9068941 20211008 RGD PMID:15347642|REF_RGD_ID:1359070 18364942 GNMT glycine N-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:732912 W RGD:9068941 20211008 RGD PMID:22342103|PMID:23073625|REF_RGD_ID:7242425|REF_RGD_ID:7242551 18364942 GNMT glycine N-methyltransferase gene PW:0000140 folate metabolic pathway ISO RGD:2719 W RGD:9068941 20211008 RGD PMID:15347642|REF_RGD_ID:1359070 18364942 GNMT glycine N-methyltransferase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:2719 W RGD:9068941 20211008 RGD PMID:8278367|REF_RGD_ID:1545057 18364942 GNMT glycine N-methyltransferase gene PW:0000398 homocysteine metabolic pathway ISO RGD:2719 W RGD:9068941 20211008 RGD PMID:15347642|REF_RGD_ID:1359070 18364942 GNMT glycine N-methyltransferase gene PW:0001670 sarcosinemia pathway ISO RGD:732912 W RGD:9068941 20211008 SMPDB SMP:00244 18364942 GNMT glycine N-methyltransferase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:732912 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18364942 GNMT glycine N-methyltransferase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:732912 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18364942 GNMT glycine N-methyltransferase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:732912 W RGD:9068941 20211008 SMPDB SMP:00179 18365028 PPP3CB protein phosphatase 3 catalytic subunit beta gene PW:0000315 calcineurin signaling pathway ISO RGD:733965 W RGD:9068941 20211008 RGD PMID:15336966|REF_RGD_ID:1579951 18365028 PPP3CB protein phosphatase 3 catalytic subunit beta gene PW:0000394 dopamine signaling pathway ISO RGD:733965 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18365028 PPP3CB protein phosphatase 3 catalytic subunit beta gene PW:0000914 interleukin-12 signaling pathway ISO RGD:733965 W RGD:9068941 20211008 PID PID:200045 18365064 FAF1 Fas associated factor 1 gene PW:0000568 aldosterone signaling pathway ISO RGD:733981 W RGD:9068941 20211008 RGD PMID:21784126|REF_RGD_ID:7421504 18365111 NME4 NME/NM23 nucleoside diphosphate kinase 4 gene PW:0000862 de novo pyrimidine biosynthetic pathway ISO RGD:1318408 W RGD:9068941 20211008 RGD PMID:11768308|REF_RGD_ID:5134680 18365111 NME4 NME/NM23 nucleoside diphosphate kinase 4 gene PW:0001344 cardiolipin metabolic pathway ISO RGD:1318408 W RGD:9068941 20211008 RGD PMID:24769127|REF_RGD_ID:10400850 18365169 TAF1C TATA-box binding protein associated factor, RNA polymerase I subunit C gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1313816 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22960599|REF_RGD_ID:9588243|REF_RGD_ID:9588244 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0000043 pyruvate metabolic pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00060 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0001416 Leigh disease pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00196 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00559 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00212 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00334 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00558 18365292 HAGH hydroxyacylglutathione hydrolase gene PW:0002615 glyoxalase metabolic pathway ISO RGD:736814 W RGD:9068941 20211008 SMPDB SMP:00459 18365384 TRIP10 thyroid hormone receptor interactor 10 gene PW:0000143 insulin signaling pathway ISO RGD:732056 W RGD:9068941 20211008 PID PID:200014 18365384 TRIP10 thyroid hormone receptor interactor 10 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:732056 W RGD:9068941 20211008 PID PID:200196 18365466 MBTPS2 membrane bound transcription factor peptidase, site 2 gene PW:0000753 sterol regulatory element-binding protein signaling pathway ISO RGD:1342985 W RGD:9068941 20211008 RGD PMID:19933148|REF_RGD_ID:2317203 18365493 LOC103224275 glutathione S-transferase Mu 1 gene PW:0000373 glutathione conjugation pathway ISO RGD:736060 W RGD:9068941 20211008 RGD PMID:10720752|REF_RGD_ID:1358120 18365493 LOC103224275 glutathione S-transferase Mu 1 gene PW:0002108 cyclophosphamide pharmacokinetics pathway ISO RGD:736060 W RGD:9068941 20211008 SMPDB SMP:00604 18365493 LOC103224275 glutathione S-transferase Mu 1 gene PW:0002109 cyclophosphamide pharmacodynamics pathway ISO RGD:736060 W RGD:9068941 20211008 SMPDB SMP:00447 18365505 STS steroid sulfatase gene PW:0000778 testosterone biosynthetic pathway ISO RGD:735809 W RGD:9068941 20211008 RGD PMID:21693170|REF_RGD_ID:6893583 18365505 STS steroid sulfatase gene PW:0000781 estradiol biosynthetic pathway ISO RGD:735809 W RGD:9068941 20211008 RGD PMID:21693170|REF_RGD_ID:6893583 18365635 RHO rhodopsin gene PW:0000962 visual phototransduction pathway ISO RGD:731395 W RGD:9068941 20211008 RGD PMID:21704730|REF_RGD_ID:6893536 18365635 RHO rhodopsin gene PW:0001005 retinoid cycle metabolic pathway ISO RGD:731395 W RGD:9068941 20211008 RGD PMID:21704730|REF_RGD_ID:6893536 18365635 RHO rhodopsin gene PW:0001495 altered visual phototransduction pathway ISO RGD:731395 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18365635 RHO rhodopsin gene PW:0001497 retinitis pigmentosa pathway ISO RGD:731395 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18366010 POP5 POP5 homolog, ribonuclease P/MRP subunit gene PW:0001573 tRNA maturation pathway ISO RGD:1323474 W RGD:9068941 20211008 RGD PMID:19931535|REF_RGD_ID:9685326 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00133 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00132 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00134 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001880 iminoglycinuria pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00193 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00105 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0001977 Hartnup disease pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00189 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00100 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00115 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00097 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00122 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00088 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00078 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00090 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002214 cystinuria pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00723 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00118 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00135 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00121 18366050 SLC12A1 solute carrier family 12 member 1 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:731943 W RGD:9068941 20211008 SMPDB SMP:00108 18366092 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1313282 W RGD:9068941 20211008 PID PID:200102 18366092 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1313282 W RGD:9068941 20211008 PID PID:200052 18366092 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 gene PW:0000961 ceramide signaling pathway ISO RGD:1313282 W RGD:9068941 20211008 PID PID:200119 18366240 ADCY2 adenylate cyclase 2 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:734219 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18366240 ADCY2 adenylate cyclase 2 gene PW:0000365 melanocortin system pathway ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00310 18366240 ADCY2 adenylate cyclase 2 gene PW:0000506 endothelin signaling pathway ISO RGD:734219 W RGD:9068941 20211008 PID PID:200005 18366240 ADCY2 adenylate cyclase 2 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:734219 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18366240 ADCY2 adenylate cyclase 2 gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00322 18366240 ADCY2 adenylate cyclase 2 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00308 18366240 ADCY2 adenylate cyclase 2 gene PW:0000998 adenosine signaling pathway ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18366240 ADCY2 adenylate cyclase 2 gene PW:0001070 luteinizing hormone signaling pathway ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00338 18366240 ADCY2 adenylate cyclase 2 gene PW:0001071 follicle-stimulating hormone signaling pathway ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00333 18366240 ADCY2 adenylate cyclase 2 gene PW:0001091 serotonin signaling pathway via receptors engaging G alphas protein family ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00309|SMP:00311|SMP:00312 18366240 ADCY2 adenylate cyclase 2 gene PW:0001530 prostaglandin D2 signaling pathway ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00343 18366240 ADCY2 adenylate cyclase 2 gene PW:0001531 prostaglandin I2 signaling pathway ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00354 18366240 ADCY2 adenylate cyclase 2 gene PW:0002119 histamine signaling pathway, immunological ISO RGD:734219 W RGD:9068941 20211008 SMPDB SMP:00335 18366302 FBXO7 F-box protein 7 gene PW:0000018 Parkinson's disease pathway ISO RGD:1313800 W RGD:9068941 20211008 RGD PMID:26223426|REF_RGD_ID:10450518 18366363 TAF2 TATA-box binding protein associated factor 2 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1353856 W RGD:9068941 20211008 RGD PMID:23146842|REF_RGD_ID:9681723 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0000640 glycolysis pathway ISO RGD:737211 W RGD:9068941 20211008 RGD PMID:18092946|REF_RGD_ID:2302794 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0000640 glycolysis pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00040 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00128 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00563 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00573 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00531 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00562 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0002360 Fanconi syndrome pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00572 18366477 PGAM1 phosphoglycerate mutase 1 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:737211 W RGD:9068941 20211008 SMPDB SMP:00560 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0000064 propanoate metabolic pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00016 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00032 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0000077 beta-alanine metabolic pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00007 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001778 propionic acidemia pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00236 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00384 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001810 methylmalonic acidemia pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00200 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001811 methylmalonic aciduria, cobalamin-related pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00201 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001870 maple syrup urine disease pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00199 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001874 isovaleric acidemia pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00523 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002095 GABA aminotransferase deficiency pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00351 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00139 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00140 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002289 malonic aciduria pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00198|SMP:00502 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00138 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002565 carnosinemia pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00493 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18366713 ALDH6A1 aldehyde dehydrogenase 6 family member A1 gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:1344188 W RGD:9068941 20211008 SMPDB SMP:00237 18366798 CYP8B1 cytochrome P450 family 8 subfamily B member 1 gene PW:0000039 bile acid biosynthetic pathway ISO RGD:736649 W RGD:9068941 20211008 SMPDB SMP:00035 18366798 CYP8B1 cytochrome P450 family 8 subfamily B member 1 gene PW:0001415 Zellweger syndrome pathway ISO RGD:736649 W RGD:9068941 20211008 SMPDB SMP:00316 18366798 CYP8B1 cytochrome P450 family 8 subfamily B member 1 gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:736649 W RGD:9068941 20211008 SMPDB SMP:00315 18366798 CYP8B1 cytochrome P450 family 8 subfamily B member 1 gene PW:0002302 familial hypercholanemia pathway ISO RGD:736649 W RGD:9068941 20211008 SMPDB SMP:00317 18366798 CYP8B1 cytochrome P450 family 8 subfamily B member 1 gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:736649 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18366815 DDX24 DEAD-box helicase 24 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1353174 W RGD:9068941 20211008 RGD PMID:22922795|REF_RGD_ID:10002738 18367023 PDE3B phosphodiesterase 3B gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:732966 W RGD:9068941 20211008 RGD PMID:17376027|REF_RGD_ID:2312479 18367083 DDX46 DEAD-box helicase 46 gene PW:0001073 spliceosome pathway ISO RGD:734266 W RGD:9068941 20211008 RGD PMID:23454554|REF_RGD_ID:9686093 18367277 PELI1 pellino E3 ubiquitin protein ligase 1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1322532 W RGD:9068941 20211008 RGD PMID:20086235|REF_RGD_ID:5490215 18367288 SLC2A3 solute carrier family 2 member 3 gene PW:0000560 facilitative sugar transporter mediated glucose transport pathway ISO RGD:3706 W RGD:9068941 20211008 RGD PMID:15320870|REF_RGD_ID:1642813 18367288 SLC2A3 solute carrier family 2 member 3 gene PW:0000560 facilitative sugar transporter mediated glucose transport pathway ISO RGD:737055 W RGD:9068941 20211008 RGD PMID:15449578|PMID:15466941|REF_RGD_ID:1625539|REF_RGD_ID:1626159 18367334 VAMP7 vesicle associated membrane protein 7 gene PW:0000278 autophagy pathway ISO RGD:1350434 W RGD:9068941 20211008 RGD PMID:20548331|REF_RGD_ID:4892310 18367409 PDHX pyruvate dehydrogenase complex component X gene PW:0000043 pyruvate metabolic pathway ISO RGD:1352009 W RGD:9068941 20211008 RGD PMID:11795479|REF_RGD_ID:2307427 18367448 TSC2 TSC complex subunit 2 gene PW:0000007 mitogen activated protein kinase signaling pathway ISO RGD:3908 W RGD:9068941 20211008 RGD PMID:14612383|REF_RGD_ID:1580517 18367448 TSC2 TSC complex subunit 2 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:736193 W RGD:9068941 20211008 RGD PMID:15150271|REF_RGD_ID:1580097 18367448 TSC2 TSC complex subunit 2 gene PW:0000180 mTOR signaling pathway ISO RGD:3908 W RGD:9068941 20211008 RGD PMID:12869586|REF_RGD_ID:1580520 18367448 TSC2 TSC complex subunit 2 gene PW:0000180 mTOR signaling pathway ISO RGD:736193 W RGD:9068941 20211008 PID PID:200096 18367448 TSC2 TSC complex subunit 2 gene PW:0000180 mTOR signaling pathway ISO RGD:736193 W RGD:9068941 20211008 RGD PMID:16885148|PMID:19339977|PMID:26159692|REF_RGD_ID:11535034|REF_RGD_ID:1625616|REF_RGD_ID:2308795 18367448 TSC2 TSC complex subunit 2 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:3908 W RGD:9068941 20211008 RGD PMID:12511557|REF_RGD_ID:1304267 18367448 TSC2 TSC complex subunit 2 gene PW:0000206 transforming growth factor-beta signaling pathway ISO RGD:736193 W RGD:9068941 20211008 RGD PMID:15066998|REF_RGD_ID:1580519 18367535 RBM22 RNA binding motif protein 22 gene PW:0001073 spliceosome pathway ISO RGD:1314003 W RGD:9068941 20211008 RGD PMID:23742842|REF_RGD_ID:9686094 18367678 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide gene PW:0001073 spliceosome pathway ISO RGD:1314912 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18367706 LIG3 DNA ligase 3 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1320452 W RGD:9068941 20211008 RGD PMID:21601536|REF_RGD_ID:7246935 18367936 GZMB granzyme B gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1353495 W RGD:9068941 20211008 PID PID:200045 18368004 ITGB6 integrin subunit beta 6 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1346382 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18368150 GADD45B growth arrest and DNA damage inducible beta gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1319220 W RGD:9068941 20211008 PID PID:200018 18368150 GADD45B growth arrest and DNA damage inducible beta gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1319220 W RGD:9068941 20211008 PID PID:200045 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000122 Hedgehog signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200172 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200197 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200188 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000394 dopamine signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 RGD PMID:14715913|REF_RGD_ID:2312475 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000565 eicosanoid signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200082 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000659 syndecan signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200156|PID:200192 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00296 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000968 interleukin-3 signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200145 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1344608 W RGD:9068941 20211008 PID PID:200019 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00379 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00665 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00376 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00375 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00659 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00660 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00323 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00307 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00324 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00380 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00381 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00382 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00366 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00302 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00378 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00332 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00331 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00301 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00325 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00359 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002134 bupranolol drug pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00670 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00670 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00300 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00299 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00296 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00298 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00305 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00303 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00306 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00326 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00666 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00327 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00329 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00662 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00663 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00328 18368211 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:1344608 W RGD:9068941 20211008 SMPDB SMP:00367 18368220 ROR2 receptor tyrosine kinase like orphan receptor 2 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1313207 W RGD:9068941 20211008 PID PID:200020 18368262 ENO1 enolase 1 gene PW:0000204 Notch signaling pathway ISO RGD:735808 W RGD:9068941 20211008 PID PID:200015 18368262 ENO1 enolase 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:735808 W RGD:9068941 20211008 PID PID:200202 18368262 ENO1 enolase 1 gene PW:0000640 glycolysis pathway ISO RGD:735808 W RGD:9068941 20211008 RGD PMID:18560153|REF_RGD_ID:2302799 18368262 ENO1 enolase 1 gene PW:0000640 glycolysis pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00040 18368262 ENO1 enolase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:2553 W RGD:9068941 20211008 RGD PMID:2966075|REF_RGD_ID:2302802 18368262 ENO1 enolase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00128 18368262 ENO1 enolase 1 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00563 18368262 ENO1 enolase 1 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18368262 ENO1 enolase 1 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00573 18368262 ENO1 enolase 1 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00531 18368262 ENO1 enolase 1 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00562 18368262 ENO1 enolase 1 gene PW:0002360 Fanconi syndrome pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00572 18368262 ENO1 enolase 1 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:735808 W RGD:9068941 20211008 SMPDB SMP:00560 18368307 SLC22A4 solute carrier family 22 member 4 gene PW:0001510 cisplatin response pathway ISO RGD:621149 W RGD:9068941 20211008 RGD PMID:24278698|REF_RGD_ID:8548480 18368307 SLC22A4 solute carrier family 22 member 4 gene PW:0001510 cisplatin response pathway ISO RGD:733281 W RGD:9068941 20211008 RGD PMID:24278698|REF_RGD_ID:8548480 18368402 PNKP polynucleotide kinase 3'-phosphatase gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:1344743 W RGD:9068941 20211008 RGD PMID:20192759|REF_RGD_ID:8662352 18368464 POLR1F RNA polymerase I subunit F gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1317243 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 PID PID:200102 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 PID PID:200149 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 RGD PMID:17306896|REF_RGD_ID:2293875 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1560043 W RGD:9068941 20211008 RGD PMID:10051439|PMID:15680699|PMID:17064355|REF_RGD_ID:2298561|REF_RGD_ID:2298567|REF_RGD_ID:2298577 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000388 Reelin signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 PID PID:200062 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000681 FasL mediated signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 PID PID:200080 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0000998 adenosine signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18368494 MAP2K7 mitogen-activated protein kinase kinase 7 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:1347407 W RGD:9068941 20211008 SMPDB SMP:00358 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00296 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00379 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00665 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00376 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00375 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00659 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00660 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00323 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00307 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00324 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00380 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00381 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00382 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00366 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00302 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00378 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00332 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00331 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00301 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00325 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00359 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002134 bupranolol drug pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00670 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00670 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00300 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00299 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00296 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00298 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00305 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00303 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00306 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00326 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00666 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00327 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00329 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00662 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00663 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00328 18368523 KCNJ5 potassium inwardly rectifying channel subfamily J member 5 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:1349904 W RGD:9068941 20211008 SMPDB SMP:00367 18368550 DDX5 DEAD-box helicase 5 gene PW:0000507 estrogen signaling pathway ISO RGD:1345493 W RGD:9068941 20211008 RGD PMID:16394250|REF_RGD_ID:5128512 18368631 AK4 adenylate kinase 4 gene PW:0000867 de novo purine biosynthetic pathway ISO RGD:2078 W RGD:9068941 20211008 RGD PMID:16167529|REF_RGD_ID:5490520 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0000031 purine metabolic pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00050 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0000759 gemcitabine pharmacokinetics pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00603 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0000760 gemcitabine pharmacodynamics pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00446 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001590 xanthinuria pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00220 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001591 xanthinuria type I pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00512 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001592 xanthinuria type II pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00513 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00210 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00537 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00203 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00364 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00365 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00428 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00427 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00167 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0002294 AICA-ribosuria pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00168 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00430 18368897 RRM1 ribonucleotide reductase catalytic subunit M1 gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:737409 W RGD:9068941 20211008 SMPDB SMP:00535 18369150 BGLAP bone gamma-carboxyglutamate protein gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:619567 W RGD:9068941 20211008 PID PID:200220 18369535 PLA2G4A phospholipase A2 group IVA gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:735872 W RGD:9068941 20211008 PID PID:200149 18369535 PLA2G4A phospholipase A2 group IVA gene PW:0000461 cyclooxygenase mediated pathway of arachidonic acid metabolism ISO RGD:735872 W RGD:9068941 20211008 RGD PMID:18761105|PMID:22679221|REF_RGD_ID:8552712|REF_RGD_ID:8552898 18369535 PLA2G4A phospholipase A2 group IVA gene PW:0000506 endothelin signaling pathway ISO RGD:735872 W RGD:9068941 20211008 PID PID:200005 18369535 PLA2G4A phospholipase A2 group IVA gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:735872 W RGD:9068941 20211008 SMPDB SMP:00358 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0000060 long term potentiation ISO RGD:68394 W RGD:9068941 20211008 RGD PMID:16141270|REF_RGD_ID:1581430 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0000455 excitatory synaptic transmission pathway ISO RGD:68394 W RGD:9068941 20211008 RGD PMID:16141270|REF_RGD_ID:1581430 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00296 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00379 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00665 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00376 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00375 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00659 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00660 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00323 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00307 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00324 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00380 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00381 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00382 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00366 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00302 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00378 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00332 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00331 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00301 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00325 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00359 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002134 bupranolol drug pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00670 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00670 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00300 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00299 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00296 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00298 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00305 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00303 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00306 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00326 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00666 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00327 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00329 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00662 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00663 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00328 18369655 KCND3 potassium voltage-gated channel subfamily D member 3 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:68576 W RGD:9068941 20211008 SMPDB SMP:00367 18370216 LGR5 leucine rich repeat containing G protein-coupled receptor 5 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1605118 W RGD:9068941 20211008 RGD PMID:23085770|REF_RGD_ID:7365107 18370253 ALDH5A1 aldehyde dehydrogenase 5 family member A1 gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:735245 W RGD:9068941 20211008 SMPDB SMP:00072 18370253 ALDH5A1 aldehyde dehydrogenase 5 family member A1 gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:735245 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18370253 ALDH5A1 aldehyde dehydrogenase 5 family member A1 gene PW:0001979 homocarnosinosis pathway ISO RGD:735245 W RGD:9068941 20211008 SMPDB SMP:00385 18370253 ALDH5A1 aldehyde dehydrogenase 5 family member A1 gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:735245 W RGD:9068941 20211008 SMPDB SMP:00136 18370309 SMYD2 SET and MYND domain containing 2 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1354091 W RGD:9068941 20211008 RGD PMID:22194015|REF_RGD_ID:7242554 18370309 SMYD2 SET and MYND domain containing 2 gene PW:0000718 p53 signaling pathway ISO RGD:1354091 W RGD:9068941 20211008 PID PID:200206 18370309 SMYD2 SET and MYND domain containing 2 gene PW:0000718 p53 signaling pathway ISO RGD:1354091 W RGD:9068941 20211008 RGD PMID:19450511|REF_RGD_ID:2316155 18370309 SMYD2 SET and MYND domain containing 2 gene PW:0001338 histone modification pathway ISO RGD:1354091 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18370335 S100A4 S100 calcium binding protein A4 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:69040 W RGD:9068941 20211008 RGD PMID:17964289|REF_RGD_ID:7204682 18370649 SNX1 sorting nexin 1 gene PW:0002430 retromer-mediated pathway ISO RGD:68962 W RGD:9068941 20211008 RGD PMID:25619244|REF_RGD_ID:10450542 18370805 LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 gene PW:0000180 mTOR signaling pathway ISO RGD:1312775 W RGD:9068941 20211008 RGD PMID:24698685|REF_RGD_ID:11535043 18370835 BLNK B cell linker gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:1347273 W RGD:9068941 20211008 PID PID:200116 18371183 MFN2 mitofusin 2 gene PW:0000009 apoptotic cell death pathway ISO RGD:628843 W RGD:9068941 20230216 RGD PMID:26485208|REF_RGD_ID:12910856 18371183 MFN2 mitofusin 2 gene PW:0001999 mitochondria fusion pathway ISO RGD:732569 W RGD:9068941 20211008 RGD PMID:21683788|PMID:24442478|REF_RGD_ID:10402101|REF_RGD_ID:10402102 18371450 CRP C-reactive protein gene PW:0000503 classical complement pathway ISO RGD:2411 W RGD:9068941 20211008 RGD PMID:16367929|REF_RGD_ID:1580273 18371450 CRP C-reactive protein gene PW:0000516 interleukin-6 signaling pathway ISO RGD:736633 W RGD:9068941 20211008 PID PID:200146 18371568 ATP2C2 ATPase secretory pathway Ca2+ transporting 2 gene PW:0001139 calcium transport pathway ISO RGD:732511 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18371568 ATP2C2 ATPase secretory pathway Ca2+ transporting 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:732511 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18371642 RIF1 replication timing regulatory factor 1 gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:1352449 W RGD:9068941 20211008 RGD PMID:24326623|REF_RGD_ID:8661237 18371642 RIF1 replication timing regulatory factor 1 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1352449 W RGD:9068941 20211008 RGD PMID:24326623|REF_RGD_ID:8661237 18371783 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 gene PW:0000580 translation initiation pathway ISO RGD:1313238 W RGD:9068941 20211008 RGD PMID:22815232|PMID:24499181|REF_RGD_ID:10002776|REF_RGD_ID:10044017 18371860 IFT88 intraflagellar transport 88 gene PW:0000122 Hedgehog signaling pathway ISO RGD:1320207 W RGD:9068941 20211008 PID PID:200172 18372009 APOH apolipoprotein H gene PW:0000474 coagulation cascade pathway ISO RGD:1321637 W RGD:9068941 20211008 RGD PMID:15507263|REF_RGD_ID:1578489 18372060 SHC1 SHC adaptor protein 1 gene PW:0000007 mitogen activated protein kinase signaling pathway ISO RGD:620446 W RGD:9068941 20211008 RGD PMID:12837289|REF_RGD_ID:1304398 18372060 SHC1 SHC adaptor protein 1 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:620446 W RGD:9068941 20211008 RGD PMID:16699171|REF_RGD_ID:1643182 18372060 SHC1 SHC adaptor protein 1 gene PW:0000143 insulin signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200014 18372060 SHC1 SHC adaptor protein 1 gene PW:0000143 insulin signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 RGD PMID:17347799|REF_RGD_ID:1625124 18372060 SHC1 SHC adaptor protein 1 gene PW:0000143 insulin signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 SMPDB SMP:00391 18372060 SHC1 SHC adaptor protein 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 RGD PMID:16829981|REF_RGD_ID:2317988 18372060 SHC1 SHC adaptor protein 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200100 18372060 SHC1 SHC adaptor protein 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200162 18372060 SHC1 SHC adaptor protein 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200220 18372060 SHC1 SHC adaptor protein 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200227 18372060 SHC1 SHC adaptor protein 1 gene PW:0000572 brain-derived neurotrophic factor signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 RGD PMID:23670594|REF_RGD_ID:11062158 18372060 SHC1 SHC adaptor protein 1 gene PW:0000578 scatter factor/hepatocyte growth factor signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 RGD PMID:14685170|PMID:18175071|REF_RGD_ID:1642762|REF_RGD_ID:2299174 18372060 SHC1 SHC adaptor protein 1 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200098 18372060 SHC1 SHC adaptor protein 1 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200022 18372060 SHC1 SHC adaptor protein 1 gene PW:0000968 interleukin-3 signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200145 18372060 SHC1 SHC adaptor protein 1 gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200019 18372060 SHC1 SHC adaptor protein 1 gene PW:0000987 erythropoietin signaling pathway ISO RGD:1346921 W RGD:9068941 20211008 PID PID:200183 18372167 PNPLA4 patatin like phospholipase domain containing 4 gene PW:0000141 retinol metabolic pathway ISO RGD:1346226 W RGD:9068941 20211008 SMPDB SMP:00074 18372167 PNPLA4 patatin like phospholipase domain containing 4 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1346226 W RGD:9068941 20211008 SMPDB SMP:00336 18372210 DCP2 decapping mRNA 2 gene PW:0000808 microRNA pathway ISO RGD:1349747 W RGD:9068941 20211008 RGD PMID:24352420|REF_RGD_ID:9850104 18372272 VAV2 vav guanine nucleotide exchange factor 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1314818 W RGD:9068941 20211008 PID PID:200149 18372272 VAV2 vav guanine nucleotide exchange factor 2 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1314818 W RGD:9068941 20211008 PID PID:200142|PID:200216 18372272 VAV2 vav guanine nucleotide exchange factor 2 gene PW:0000987 erythropoietin signaling pathway ISO RGD:1314818 W RGD:9068941 20211008 PID PID:200183 18372272 VAV2 vav guanine nucleotide exchange factor 2 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1314818 W RGD:9068941 20211008 PID PID:200124 18372444 GRIK1 glutamate ionotropic receptor kainate type subunit 1 gene PW:0000060 long term potentiation ISO RGD:731546 W RGD:9068941 20211008 RGD PMID:10580501|REF_RGD_ID:1642498 18372724 TSEN2 tRNA splicing endonuclease subunit 2 gene PW:0001573 tRNA maturation pathway ISO RGD:1603298 W RGD:9068941 20211008 RGD PMID:25071838|REF_RGD_ID:9685342 18372943 DUSP16 dual specificity phosphatase 16 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1321793 W RGD:9068941 20211008 RGD PMID:20626350|REF_RGD_ID:7240533 18372943 DUSP16 dual specificity phosphatase 16 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1321793 W RGD:9068941 20211008 RGD PMID:17208316|REF_RGD_ID:2293881 18372961 ACTA2 actin alpha 2, smooth muscle gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1348351 W RGD:9068941 20211008 PID PID:200149 18372988 AACS acetoacetyl-CoA synthetase gene PW:0000069 ketone bodies metabolic pathway ISO RGD:732340 W RGD:9068941 20211008 RGD PMID:15877199|REF_RGD_ID:2326093 18373041 SLC47A1 solute carrier family 47 member 1 gene PW:0001489 metformin pharmacokinetics pathway ISO RGD:1605371 W RGD:9068941 20211008 RGD PMID:22722338|REF_RGD_ID:7794727 18373041 SLC47A1 solute carrier family 47 member 1 gene PW:0001510 cisplatin response pathway ISO RGD:1605371 W RGD:9068941 20211008 RGD PMID:24278698|REF_RGD_ID:8548480 18373396 MYO6 myosin VI gene PW:0000992 E-cadherin signaling pathway ISO RGD:1352294 W RGD:9068941 20211008 PID PID:200182 18373396 MYO6 myosin VI gene PW:0001503 auditory mechanotransduction pathway ISO RGD:1352294 W RGD:9068941 20211008 RGD PMID:20624897|PMID:22715884|REF_RGD_ID:8547669|REF_RGD_ID:8547672 18373672 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon gene PW:0000180 mTOR signaling pathway ISO RGD:1350802 W RGD:9068941 20211008 PID PID:200096 18373672 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:1350802 W RGD:9068941 20211008 PID PID:200197 18373672 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:1350802 W RGD:9068941 20211008 PID PID:200100 18373672 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1350802 W RGD:9068941 20211008 PID PID:200149 18373672 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1350802 W RGD:9068941 20211008 PID PID:200227 18373672 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1350802 W RGD:9068941 20211008 PID PID:200196 18373729 KCNJ14 potassium inwardly rectifying channel subfamily J member 14 gene PW:0000274 neuron-to-neuron signaling pathway via the chemical synapse ISO RGD:628872 W RGD:9068941 20211008 RGD PMID:15936845|REF_RGD_ID:1581471 18373785 KCNN3 potassium calcium-activated channel subfamily N member 3 gene PW:0000241 schizophrenia pathway ISO RGD:733381 W RGD:9068941 20211008 RGD PMID:12007452|REF_RGD_ID:1358338 18373785 KCNN3 potassium calcium-activated channel subfamily N member 3 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:733381 W RGD:9068941 20211008 RGD PMID:21942705|REF_RGD_ID:7204683 18373878 CASP1 caspase 1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:735988 W RGD:9068941 20211008 PID PID:200089 18373878 CASP1 caspase 1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:735988 W RGD:9068941 20211008 RGD PMID:19302047|PMID:20303873|REF_RGD_ID:5490210|REF_RGD_ID:5490211 18373878 CASP1 caspase 1 gene PW:0000896 type II interferon signaling pathway ISO RGD:735988 W RGD:9068941 20211008 PID PID:200129 18373897 MDH2 malate dehydrogenase 2 gene PW:0000026 citric acid cycle pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00057 18373897 MDH2 malate dehydrogenase 2 gene PW:0000641 gluconeogenesis pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00128 18373897 MDH2 malate dehydrogenase 2 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00563 18373897 MDH2 malate dehydrogenase 2 gene PW:0001754 pyruvate dehydrogenase E2 deficiency pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00551 18373897 MDH2 malate dehydrogenase 2 gene PW:0001755 pyruvate dehydrogenase E3 deficiency pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00550 18373897 MDH2 malate dehydrogenase 2 gene PW:0001814 mitochondrial complex II deficiency pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00548 18373897 MDH2 malate dehydrogenase 2 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18373897 MDH2 malate dehydrogenase 2 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00573 18373897 MDH2 malate dehydrogenase 2 gene PW:0002098 fumaric aciduria pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00547 18373897 MDH2 malate dehydrogenase 2 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00562 18373897 MDH2 malate dehydrogenase 2 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:733026 W RGD:9068941 20211008 RGD PMID:16368075|PMID:18020963|REF_RGD_ID:11251688|REF_RGD_ID:5129954 18373897 MDH2 malate dehydrogenase 2 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00129 18373897 MDH2 malate dehydrogenase 2 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:733026 W RGD:9068941 20211008 SMPDB SMP:00560 18373928 PTK7 protein tyrosine kinase 7 (inactive) gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1614323 W RGD:9068941 20211008 RGD PMID:17226800|REF_RGD_ID:2293492 18373983 BST1 bone marrow stromal cell antigen 1 gene PW:0001010 niacin metabolic pathway ISO RGD:1342632 W RGD:9068941 20211008 SMPDB SMP:00048 18373983 BST1 bone marrow stromal cell antigen 1 gene PW:0002583 ADP-ribosylation pathway, cyclic ribosylation ISO RGD:1342632 W RGD:9068941 20211008 RGD PMID:23576305|REF_RGD_ID:11250406 18373996 VAMP2 vesicle associated membrane protein 2 gene PW:0000491 vasopressin signaling pathway ISO RGD:735448 W RGD:9068941 20211008 RGD PMID:18431594|REF_RGD_ID:2312656 18373996 VAMP2 vesicle associated membrane protein 2 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:735448 W RGD:9068941 20211008 PID PID:200196 18373996 VAMP2 vesicle associated membrane protein 2 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:735448 W RGD:9068941 20211008 RGD PMID:17717074|PMID:18570632|REF_RGD_ID:2302393|REF_RGD_ID:2302397 18373996 VAMP2 vesicle associated membrane protein 2 gene PW:0000674 insulin secretion pathway ISO RGD:735449 W RGD:9068941 20211008 RGD PMID:19295123|REF_RGD_ID:2311087 18373996 VAMP2 vesicle associated membrane protein 2 gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:735448 W RGD:9068941 20211008 RGD PMID:18431594|REF_RGD_ID:2312656 18374040 SLC28A3 solute carrier family 28 member 3 gene PW:0000759 gemcitabine pharmacokinetics pathway ISO RGD:731872 W RGD:9068941 20211008 SMPDB SMP:00603 18374040 SLC28A3 solute carrier family 28 member 3 gene PW:0000760 gemcitabine pharmacodynamics pathway ISO RGD:731872 W RGD:9068941 20211008 SMPDB SMP:00446 18374040 SLC28A3 solute carrier family 28 member 3 gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:731872 W RGD:9068941 20211008 SMPDB SMP:00609 18374040 SLC28A3 solute carrier family 28 member 3 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:731872 W RGD:9068941 20211008 SMPDB SMP:00428 18374040 SLC28A3 solute carrier family 28 member 3 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:731872 W RGD:9068941 20211008 SMPDB SMP:00427 18374040 SLC28A3 solute carrier family 28 member 3 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:731872 W RGD:9068941 20211008 SMPDB SMP:00430 18374096 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 gene PW:0000387 Arf family mediated signaling pathway ISO RGD:1319955 W RGD:9068941 20211008 PID PID:200195 18374280 BAP1 BRCA1 associated deubiquitinase 1 gene PW:0001338 histone modification pathway ISO RGD:1323652 W RGD:9068941 20211008 RGD PMID:24647359|REF_RGD_ID:9479061 18374361 DUOX2 dual oxidase 2 gene PW:0002521 thyroid hormone biosynthetic pathway ISO RGD:1353863 W RGD:9068941 20211008 SMPDB SMP:00716 18374431 SHB SH2 domain containing adaptor protein B gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1350494 W RGD:9068941 20211008 PID PID:200188 18374431 SHB SH2 domain containing adaptor protein B gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1350494 W RGD:9068941 20211008 RGD PMID:17658244|REF_RGD_ID:2298729 18374431 SHB SH2 domain containing adaptor protein B gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1350494 W RGD:9068941 20211008 PID PID:200162 18374512 SYT1 synaptotagmin 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:3803 W RGD:9068941 20211008 RGD PMID:11751925|REF_RGD_ID:2311146 18374512 SYT1 synaptotagmin 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:736944 W RGD:9068941 20211008 RGD PMID:15534041|REF_RGD_ID:7204679 18374795 EIF3A eukaryotic translation initiation factor 3 subunit A gene PW:0000580 translation initiation pathway ISO RGD:1316362 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18374923 WLS Wnt ligand secretion mediator gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1605334 W RGD:9068941 20211008 RGD PMID:23439944|REF_RGD_ID:7365109 18375281 SNAPC5 small nuclear RNA activating complex polypeptide 5 gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1313202 W RGD:9068941 20211008 RGD PMID:23031840|REF_RGD_ID:9588284 18375354 MED16 mediator complex subunit 16 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1317518 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18375432 SSTR1 somatostatin receptor 1 gene PW:0000579 somatostatin signaling pathway ISO RGD:3762 W RGD:9068941 20211008 RGD PMID:17021051|REF_RGD_ID:1641809 18375454 ATXN7 ataxin 7 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1350255 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18375581 PCGF5 polycomb group ring finger 5 gene PW:0001338 histone modification pathway ISO RGD:1351153 W RGD:9068941 20211008 RGD PMID:23473600|PMID:25065329|REF_RGD_ID:9479058|REF_RGD_ID:9479060 18375603 FABP5 fatty acid binding protein 5 gene PW:0001004 retinoic acid metabolic pathway ISO RGD:736313 W RGD:9068941 20211008 RGD PMID:21621639|REF_RGD_ID:6484672 18375729 EPHB4 EPH receptor B4 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1353692 W RGD:9068941 20211008 PID PID:200052|PID:200204 18375750 RAB11FIP2 RAB11 family interacting protein 2 gene PW:0000491 vasopressin signaling pathway ISO RGD:1344867 W RGD:9068941 20211008 RGD PMID:17156409|PMID:18431594|REF_RGD_ID:2312655|REF_RGD_ID:2312656 18375750 RAB11FIP2 RAB11 family interacting protein 2 gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:1344867 W RGD:9068941 20211008 RGD PMID:18431594|REF_RGD_ID:2312656 18375777 GRPEL1 GrpE like 1, mitochondrial gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1345534 W RGD:9068941 20211008 RGD PMID:25542066|REF_RGD_ID:10412659 18375886 IMP4 IMP U3 small nucleolar ribonucleoprotein 4 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1605599 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:3531 W RGD:9068941 20211008 RGD PMID:16508002|PMID:17310240|PMID:9779826|REF_RGD_ID:1580106|REF_RGD_ID:1626216|REF_RGD_ID:70317 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:737596 W RGD:9068941 20211008 RGD PMID:12835716|PMID:22177953|REF_RGD_ID:1357969|REF_RGD_ID:5686410 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000143 insulin signaling pathway ISO RGD:737596 W RGD:9068941 20211008 SMPDB SMP:00391 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000180 mTOR signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200096 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200197 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200100 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200188 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200149 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000506 endothelin signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200005 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000602 altered extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:737596 W RGD:9068941 20211008 RGD PMID:17126425|REF_RGD_ID:2293882 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000907 interleukin-2 signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200098 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000961 ceramide signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200119 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:737596 W RGD:9068941 20211008 PID PID:200019 18375915 RAF1 Raf-1 proto-oncogene, serine/threonine kinase gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:737596 W RGD:9068941 20211008 SMPDB SMP:00358 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0000047 glycine, serine and threonine metabolic pathway ISO RGD:1308582 W RGD:9068941 20211008 RGD PMID:3110140|REF_RGD_ID:2300383 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0000047 glycine, serine and threonine metabolic pathway ISO RGD:1318437 W RGD:9068941 20211008 RGD PMID:15671219|REF_RGD_ID:1359815 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0000140 folate metabolic pathway ISO RGD:1318437 W RGD:9068941 20211008 RGD PMID:15671219|REF_RGD_ID:1359815 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:1308582 W RGD:9068941 20211008 RGD PMID:3110140|REF_RGD_ID:2300383 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:1318437 W RGD:9068941 20211008 RGD PMID:15671219|PMID:22332074|REF_RGD_ID:1359815|REF_RGD_ID:7242561 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0000440 glycine metabolic pathway ISO RGD:1308582 W RGD:9068941 20211008 RGD PMID:3110140|REF_RGD_ID:2300383 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0001207 folate cycle metabolic pathway ISO RGD:1318437 W RGD:9068941 20211008 RGD PMID:20645850|PMID:22108709|REF_RGD_ID:7242557|REF_RGD_ID:7242560 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0001670 sarcosinemia pathway ISO RGD:1318437 W RGD:9068941 20211008 SMPDB SMP:00244 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1318437 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1318437 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18375947 SHMT2 serine hydroxymethyltransferase 2 gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1318437 W RGD:9068941 20211008 SMPDB SMP:00179 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:2659 W RGD:9068941 20211008 RGD PMID:15533043|REF_RGD_ID:1359081 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0000050 arginine and proline metabolic pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00020 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0000398 homocysteine metabolic pathway ISO RGD:2659 W RGD:9068941 20211008 RGD PMID:15533043|REF_RGD_ID:1359081 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0000404 creatine metabolic pathway ISO RGD:2659 W RGD:9068941 20211008 RGD PMID:12069495|REF_RGD_ID:1359082 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0001670 sarcosinemia pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00244 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0001807 gyrate atrophy pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00363 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0001931 hyperprolinemia type I pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00361 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0001932 hyperprolinemia type II pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00360 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0002181 prolidase deficiency pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00207 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00179 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0002359 AGAT deficiency pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18376282 GAMT guanidinoacetate N-methyltransferase gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:732024 W RGD:9068941 20211008 SMPDB SMP:00506 18376463 ACTN4 actinin alpha 4 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:735302 W RGD:9068941 20211008 PID PID:200149 18376527 ACTR8 actin related protein 8 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1323563 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18376841 ITGB5 integrin subunit beta 5 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1349145 W RGD:9068941 20211008 RGD PMID:17543136|PMID:8799848|REF_RGD_ID:41410438|REF_RGD_ID:5135538 18377116 PGLS 6-phosphogluconolactonase gene PW:0000045 pentose phosphate pathway ISO RGD:1315936 W RGD:9068941 20211008 SMPDB SMP:00031 18377116 PGLS 6-phosphogluconolactonase gene PW:0000573 pentose phosphate pathway - oxidative phase ISO RGD:1307001 W RGD:9068941 20211008 RGD PMID:971315|REF_RGD_ID:2311501 18377116 PGLS 6-phosphogluconolactonase gene PW:0001629 transaldolase deficiency pathway ISO RGD:1315936 W RGD:9068941 20211008 SMPDB SMP:00520 18377116 PGLS 6-phosphogluconolactonase gene PW:0001704 ribose 5-phosphate isomerase deficiency pathway ISO RGD:1315936 W RGD:9068941 20211008 SMPDB SMP:00519 18377191 FGF6 fibroblast growth factor 6 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:732549 W RGD:9068941 20211008 PID PID:200220 18377191 FGF6 fibroblast growth factor 6 gene PW:0000659 syndecan signaling pathway ISO RGD:732549 W RGD:9068941 20211008 PID PID:200134 18377220 MPI mannose phosphate isomerase gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:1349436 W RGD:9068941 20211008 SMPDB SMP:00064 18377220 MPI mannose phosphate isomerase gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:1349436 W RGD:9068941 20211008 SMPDB SMP:00725 18377220 MPI mannose phosphate isomerase gene PW:0002388 fructosuria pathway ISO RGD:1349436 W RGD:9068941 20211008 SMPDB SMP:00561 18377286 ITGAL integrin subunit alpha L gene PW:0000286 integrin mediated signaling pathway ISO RGD:1352170 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18377371 RAB7A RAB7A, member RAS oncogene family gene PW:0000278 autophagy pathway ISO RGD:1351789 W RGD:9068941 20211008 RGD PMID:20548331|REF_RGD_ID:4892310 18377371 RAB7A RAB7A, member RAS oncogene family gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1351789 W RGD:9068941 20211008 PID PID:200045 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00133 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00132 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00134 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001880 iminoglycinuria pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00193 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00105 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0001977 Hartnup disease pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00189 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00100 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00115 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00097 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00122 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00088 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00078 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00090 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002214 cystinuria pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00723 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00118 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00135 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00121 18377395 SLC12A6 solute carrier family 12 member 6 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:1322734 W RGD:9068941 20211008 SMPDB SMP:00108 18377668 WDR82 WD repeat domain 82 gene PW:0001338 histone modification pathway ISO RGD:1604285 W RGD:9068941 20211008 RGD PMID:22663077|REF_RGD_ID:9479053 18377681 KMT5A lysine methyltransferase 5A gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1602807 W RGD:9068941 20211008 RGD PMID:22194015|REF_RGD_ID:7242554 18377681 KMT5A lysine methyltransferase 5A gene PW:0000718 p53 signaling pathway ISO RGD:1602807 W RGD:9068941 20211008 PID PID:200206 18377681 KMT5A lysine methyltransferase 5A gene PW:0001338 histone modification pathway ISO RGD:1602807 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18377799 NUP62 nucleoporin 62 gene PW:0001587 mRNA nuclear export pathway ISO RGD:1349933 W RGD:9068941 20211008 RGD PMID:25184662|REF_RGD_ID:9743947 18377811 STIM2 stromal interaction molecule 2 gene PW:0001139 calcium transport pathway ISO RGD:1312198 W RGD:9068941 20211008 RGD PMID:22914293|REF_RGD_ID:7204692 18377811 STIM2 stromal interaction molecule 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1312198 W RGD:9068941 20211008 RGD PMID:22914293|REF_RGD_ID:7204692 18377858 SLC8A2 solute carrier family 8 member A2 gene PW:0001139 calcium transport pathway ISO RGD:731774 W RGD:9068941 20211008 RGD PMID:17716241|REF_RGD_ID:7204698 18377858 SLC8A2 solute carrier family 8 member A2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:731774 W RGD:9068941 20211008 RGD PMID:17716241|REF_RGD_ID:7204698 18378082 CTNNBL1 catenin beta like 1 gene PW:0001073 spliceosome pathway ISO RGD:1346196 W RGD:9068941 20211008 RGD PMID:23742842|REF_RGD_ID:9686094 18378173 TARBP2 TARBP2 subunit of RISC loading complex gene PW:0000808 microRNA pathway ISO RGD:1316539 W RGD:9068941 20211008 RGD PMID:20661255|REF_RGD_ID:4144851 18378275 PRMT2 protein arginine methyltransferase 2 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1605435 W RGD:9068941 20211008 RGD PMID:21074527|REF_RGD_ID:7242552 18378275 PRMT2 protein arginine methyltransferase 2 gene PW:0001338 histone modification pathway ISO RGD:1605435 W RGD:9068941 20211008 RGD PMID:24583552|REF_RGD_ID:9479047 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:735631 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:735631 W RGD:9068941 20211008 SMPDB SMP:00130 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0000773 aldosterone biosynthetic pathway ISO RGD:735631 W RGD:9068941 20211008 RGD PMID:17926129|REF_RGD_ID:4892309 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0000774 cortisol biosynthetic pathway ISO RGD:735631 W RGD:9068941 20211008 RGD PMID:17926129|REF_RGD_ID:4892309 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0000778 testosterone biosynthetic pathway ISO RGD:735631 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0000781 estradiol biosynthetic pathway ISO RGD:735631 W RGD:9068941 20211008 RGD PMID:17926129|REF_RGD_ID:4892309 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0001479 lipoid congenital adrenal hyperplasia pathway ISO RGD:735631 W RGD:9068941 20211008 SMPDB SMP:00371 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0002166 17-alpha-hydroxylase deficiency pathway ISO RGD:735631 W RGD:9068941 20211008 SMPDB SMP:00372 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0002167 21-alpha-hydroxylase deficiency pathway ISO RGD:735631 W RGD:9068941 20211008 SMPDB SMP:00373 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0002168 11-beta-hydroxylase deficiency pathway ISO RGD:735631 W RGD:9068941 20211008 SMPDB SMP:00575 18378324 CYP11A1 cytochrome P450 family 11 subfamily A member 1 gene PW:0002466 apparent mineralocorticoid excess syndrome pathway ISO RGD:735631 W RGD:9068941 20211008 SMPDB SMP:00717 18378437 FADS2 fatty acid desaturase 2 gene PW:0000523 linoleic acid metabolic pathway ISO RGD:68475 W RGD:9068941 20211008 SMPDB SMP:00018 18378437 FADS2 fatty acid desaturase 2 gene PW:0001158 alpha-linolenic acid metabolic pathway ISO RGD:68475 W RGD:9068941 20211008 SMPDB SMP:00018 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00133 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00132 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00134 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001880 iminoglycinuria pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00193 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00105 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0001977 Hartnup disease pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00189 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00100 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00115 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00097 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00122 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00088 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00078 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00090 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002214 cystinuria pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00723 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00118 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00135 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00121 18378598 SCNN1B sodium channel epithelial 1 subunit beta gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:734263 W RGD:9068941 20211008 SMPDB SMP:00108 18378658 XRCC6 X-ray repair cross complementing 6 gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:732846 W RGD:9068941 20211008 RGD PMID:20192759|REF_RGD_ID:8662352 18378684 TGFB2 transforming growth factor beta 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:730953 W RGD:9068941 20211008 PID PID:200168 18378684 TGFB2 transforming growth factor beta 2 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:730953 W RGD:9068941 20211008 PID PID:200227 18378684 TGFB2 transforming growth factor beta 2 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:730954 W RGD:9068941 20211008 RGD PMID:15109563|REF_RGD_ID:2298921 18378684 TGFB2 transforming growth factor beta 2 gene PW:0000658 glypican signaling pathway ISO RGD:730953 W RGD:9068941 20211008 PID PID:200026 18378797 MUSK muscle associated receptor tyrosine kinase gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:11021 W RGD:9068941 20211008 RGD PMID:23032192|REF_RGD_ID:8549508 18379101 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B gene PW:0001073 spliceosome pathway ISO RGD:730896 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18379110 RSPO3 R-spondin 3 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1345376 W RGD:9068941 20211008 RGD PMID:23151663|REF_RGD_ID:7365105 18379143 EFNA5 ephrin A5 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1350398 W RGD:9068941 20211008 PID PID:200052|PID:200059|PID:200142 18379173 SLC25A13 solute carrier family 25 member 13 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:1323000 W RGD:9068941 20211008 RGD PMID:16368075|REF_RGD_ID:11251688 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0000455 excitatory synaptic transmission pathway ISO RGD:621704 W RGD:9068941 20211008 RGD PMID:16477151|REF_RGD_ID:1642190 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00671 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00431 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00413 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00402 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00686 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00687 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00691 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001940 methadone pharmacokinetics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00624 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00408 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00399 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00422 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00426 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00415 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00425 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00423 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00424 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00684 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00393 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00401 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00404 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00688 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00416 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00397 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00409 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00410 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00411 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00412 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00394 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00681 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00395 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00398 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00400 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00677 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00673 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00407 18379314 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:733376 W RGD:9068941 20211008 SMPDB SMP:00675 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:2943 W RGD:9068941 20211008 RGD PMID:9487126|REF_RGD_ID:2293350 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200149|PID:200162 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200220 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000360 hypoxia inducible factor pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200202 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000506 endothelin signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200005 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000516 interleukin-6 signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200146 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000883 interleukin-1 signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200089 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000907 interleukin-2 signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200098 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000958 forkhead class A signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200226 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:734356 W RGD:9068941 20211008 PID PID:200211 18379433 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene PW:0000998 adenosine signaling pathway ISO RGD:734356 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0000640 glycolysis pathway ISO RGD:68971 W RGD:9068941 20211008 RGD PMID:18092946|REF_RGD_ID:2302794 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0000640 glycolysis pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00040 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0000641 gluconeogenesis pathway ISO RGD:3313 W RGD:9068941 20211008 RGD PMID:15720133|REF_RGD_ID:2302795 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0000641 gluconeogenesis pathway ISO RGD:68971 W RGD:9068941 20211008 RGD PMID:18092946|REF_RGD_ID:2302794 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0000641 gluconeogenesis pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00128 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00563 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00573 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00531 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00562 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0002360 Fanconi syndrome pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00572 18379655 PGAM2 phosphoglycerate mutase 2 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:68971 W RGD:9068941 20211008 SMPDB SMP:00560 18379679 DPF3 double PHD fingers 3 gene PW:0001338 histone modification pathway ISO RGD:1319176 W RGD:9068941 20211008 RGD PMID:23642229|REF_RGD_ID:9479074 18379679 DPF3 double PHD fingers 3 gene PW:0001406 SWI/SNF family mediated chromatin remodeling pathway ISO RGD:1319176 W RGD:9068941 20211008 RGD PMID:21358755|PMID:23355908|REF_RGD_ID:8694154|REF_RGD_ID:9495920 18379750 PRPF3 pre-mRNA processing factor 3 gene PW:0001073 spliceosome pathway ISO RGD:1321525 W RGD:9068941 20211008 RGD PMID:19239890|REF_RGD_ID:9686089 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0000049 cysteine metabolic pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00013 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0000050 arginine and proline metabolic pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00020 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0000052 tyrosine metabolic pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00006 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:2721 W RGD:9068941 20211008 RGD PMID:2966075|REF_RGD_ID:2302802 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001608 tyrosinemia type I pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00218 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001609 tyrosinemia type II pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00369 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001610 tyrosinemia type III pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00370 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001805 phenylketonuria pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00206 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001807 gyrate atrophy pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00363 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001931 hyperprolinemia type I pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00361 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0001932 hyperprolinemia type II pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00360 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00429 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002181 prolidase deficiency pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00207 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002208 dopamine beta-hydroxylase deficiency pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00498 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002218 ocular nonnephropathic cystinosis pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00722 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002277 alkaptonuria pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00169 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002359 AGAT deficiency pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002380 hawkinsinuria pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00190 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00506 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002568 mercaptolactate-cysteine disulfiduria pathway ISO RGD:735827 W RGD:9068941 20211008 SMPDB SMP:00499 18379781 GOT1 glutamic-oxaloacetic transaminase 1 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:735827 W RGD:9068941 20211008 RGD PMID:16368075|PMID:18020963|REF_RGD_ID:11251688|REF_RGD_ID:5129954 18379826 F7 coagulation factor VII gene PW:0000474 coagulation cascade pathway ISO RGD:1345586 W RGD:9068941 20211008 RGD PMID:12356487|PMID:12787532|PMID:26018600|REF_RGD_ID:11342779|REF_RGD_ID:11352277|REF_RGD_ID:1580376 18379826 F7 coagulation factor VII gene PW:0000474 coagulation cascade pathway ISO RGD:628678 W RGD:9068941 20211008 RGD PMID:10048754|REF_RGD_ID:2290183 18379826 F7 coagulation factor VII gene PW:0000731 warfarin pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00268 18379826 F7 coagulation factor VII gene PW:0001600 acenocoumarol pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00269 18379826 F7 coagulation factor VII gene PW:0001637 alteplase pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00280 18379826 F7 coagulation factor VII gene PW:0001655 aminocaproic acid pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00286 18379826 F7 coagulation factor VII gene PW:0001664 anistreplase pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00281 18379826 F7 coagulation factor VII gene PW:0001788 tranexamic acid pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00287 18379826 F7 coagulation factor VII gene PW:0002149 bivalirudin pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00277 18379826 F7 coagulation factor VII gene PW:0002223 aprotinin pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00288 18379826 F7 coagulation factor VII gene PW:0002229 argatroban pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00276 18379826 F7 coagulation factor VII gene PW:0002258 reteplase pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00285 18379826 F7 coagulation factor VII gene PW:0002329 heparin pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00274 18379826 F7 coagulation factor VII gene PW:0002332 enoxaparin pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00272 18379826 F7 coagulation factor VII gene PW:0002437 fondaparinux pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00273 18379826 F7 coagulation factor VII gene PW:0002494 phenindione pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00655 18379826 F7 coagulation factor VII gene PW:0002497 dicoumarol pharmacodynamics pathway ISO RGD:1345586 W RGD:9068941 20211008 SMPDB SMP:00270|SMP:00656 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:619908 W RGD:9068941 20211008 RGD PMID:16508002|PMID:17310240|REF_RGD_ID:1580106|REF_RGD_ID:1626216 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:735645 W RGD:9068941 20211008 RGD PMID:22177953|REF_RGD_ID:5686410 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000180 mTOR signaling pathway ISO RGD:735645 W RGD:9068941 20211008 PID PID:200096 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:735645 W RGD:9068941 20211008 PID PID:200188 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:735645 W RGD:9068941 20211008 PID PID:200149 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000602 altered extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:735645 W RGD:9068941 20211008 RGD PMID:17126425|PMID:18098337|PMID:20951313|PMID:21277552|REF_RGD_ID:2293882|REF_RGD_ID:2298531|REF_RGD_ID:5133242|REF_RGD_ID:5133243 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000612 colorectal cancer pathway ISO RGD:735645 W RGD:9068941 20211008 RGD PMID:18098337|REF_RGD_ID:2298531 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000705 non-small cell lung carcinoma pathway ISO RGD:735645 W RGD:9068941 20211008 RGD PMID:20951313|PMID:21277552|REF_RGD_ID:5133242|REF_RGD_ID:5133243 18380044 BRAF B-Raf proto-oncogene, serine/threonine kinase gene PW:0000998 adenosine signaling pathway ISO RGD:735645 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18380097 TPCN2 two pore segment channel 2 gene PW:0001139 calcium transport pathway ISO RGD:1323411 W RGD:9068941 20211008 RGD PMID:20018950|REF_RGD_ID:7204697 18380097 TPCN2 two pore segment channel 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1323411 W RGD:9068941 20211008 RGD PMID:20018950|REF_RGD_ID:7204697 18380203 PDE8A phosphodiesterase 8A gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1601777 W RGD:9068941 20211008 RGD PMID:17376027|REF_RGD_ID:2312479 18380285 CSF2RB colony stimulating factor 2 receptor subunit beta gene PW:0000968 interleukin-3 signaling pathway ISO RGD:1348418 W RGD:9068941 20211008 PID PID:200145 18380285 CSF2RB colony stimulating factor 2 receptor subunit beta gene PW:0000969 interleukin-5 signaling pathway ISO RGD:1348418 W RGD:9068941 20211008 PID PID:200107 18380285 CSF2RB colony stimulating factor 2 receptor subunit beta gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1348418 W RGD:9068941 20211008 PID PID:200019 18380367 STIL STIL centriolar assembly protein gene PW:0000122 Hedgehog signaling pathway ISO RGD:1312720 W RGD:9068941 20211008 PID PID:200168 18380409 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:734348 W RGD:9068941 20211008 SMPDB SMP:00463 18380698 CPM carboxypeptidase M gene PW:0000526 kallikrein-kinin cascade pathway ISO RGD:1321490 W RGD:9068941 20211008 RGD PMID:16177542|REF_RGD_ID:7401223 18380773 S1PR3 sphingosine-1-phosphate receptor 3 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:1352881 W RGD:9068941 20211008 PID PID:200046|PID:200123 18380864 MAML2 mastermind like transcriptional coactivator 2 gene PW:0000204 Notch signaling pathway ISO RGD:1313593 W RGD:9068941 20211008 PID PID:200015 18380864 MAML2 mastermind like transcriptional coactivator 2 gene PW:0000204 Notch signaling pathway ISO RGD:1313593 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18380882 AOC1 amine oxidase copper containing 1 gene PW:0000051 histidine metabolic pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00044 18380882 AOC1 amine oxidase copper containing 1 gene PW:0000052 tyrosine metabolic pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00006 18380882 AOC1 amine oxidase copper containing 1 gene PW:0001608 tyrosinemia type I pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00218 18380882 AOC1 amine oxidase copper containing 1 gene PW:0001978 histidinemia pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00191 18380882 AOC1 amine oxidase copper containing 1 gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00429 18380882 AOC1 amine oxidase copper containing 1 gene PW:0002208 dopamine beta-hydroxylase deficiency pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00498 18380882 AOC1 amine oxidase copper containing 1 gene PW:0002277 alkaptonuria pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00169 18380882 AOC1 amine oxidase copper containing 1 gene PW:0002380 hawkinsinuria pathway ISO RGD:732341 W RGD:9068941 20211008 SMPDB SMP:00190 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0000015 Alzheimer's disease pathway ISO RGD:621096 W RGD:9068941 20211008 RGD PMID:11020223|REF_RGD_ID:1302873 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0000144 ubiquitin/proteasome degradation pathway ISO RGD:621096 W RGD:9068941 20211008 RGD PMID:11882492|REF_RGD_ID:724779 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0000294 altered ubiquitin/proteasome degradation pathway ISO RGD:621096 W RGD:9068941 20211008 RGD PMID:11020223|REF_RGD_ID:1302873 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1348630 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1348630 W RGD:9068941 20211008 PID PID:200089 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1348630 W RGD:9068941 20211008 RGD PMID:18535784|PMID:20086235|REF_RGD_ID:5490215|REF_RGD_ID:5490218 18380891 UBE2N ubiquitin conjugating enzyme E2 N gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1348630 W RGD:9068941 20211008 RGD PMID:21533982|PMID:24326623|REF_RGD_ID:8661232|REF_RGD_ID:8661237 18381086 ARRB1 arrestin beta 1 gene PW:0000493 corticotropin-releasing hormone signaling pathway ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:16918397|REF_RGD_ID:5147673 18381086 ARRB1 arrestin beta 1 gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:16304060|REF_RGD_ID:5133417 18381086 ARRB1 arrestin beta 1 gene PW:0000794 epinephrine signaling pathway via adrenergic receptor beta ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:18268361|PMID:19229505|REF_RGD_ID:4140419|REF_RGD_ID:5135529 18381086 ARRB1 arrestin beta 1 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18381086 ARRB1 arrestin beta 1 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18381086 ARRB1 arrestin beta 1 gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:20703892|REF_RGD_ID:7207469 18381086 ARRB1 arrestin beta 1 gene PW:0001141 calcium signaling pathway via the calcium-sensing receptor ISO RGD:2156 W RGD:9068941 20211008 RGD PMID:22192592|REF_RGD_ID:7207059 18381086 ARRB1 arrestin beta 1 gene PW:0001141 calcium signaling pathway via the calcium-sensing receptor ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:15637145|REF_RGD_ID:7207060 18381086 ARRB1 arrestin beta 1 gene PW:0001480 kinin signaling pathway ISO RGD:732370 W RGD:9068941 20211008 RGD PMID:21145390|REF_RGD_ID:7411621 18381244 GJA4 gap junction protein alpha 4 gene PW:0000334 connexin signaling pathway ISO RGD:731518 W RGD:9068941 20211008 RGD PMID:15381756|REF_RGD_ID:1580398 18381259 PRKCA protein kinase C alpha gene PW:0000143 insulin signaling pathway ISO RGD:737062 W RGD:9068941 20211008 RGD PMID:17347799|REF_RGD_ID:1625124 18381259 PRKCA protein kinase C alpha gene PW:0000180 mTOR signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200096 18381259 PRKCA protein kinase C alpha gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200188 18381259 PRKCA protein kinase C alpha gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:737062 W RGD:9068941 20211008 RGD PMID:17658244|REF_RGD_ID:2298729 18381259 PRKCA protein kinase C alpha gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200149 18381259 PRKCA protein kinase C alpha gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200031 18381259 PRKCA protein kinase C alpha gene PW:0000506 endothelin signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200005 18381259 PRKCA protein kinase C alpha gene PW:0000565 eicosanoid signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200082 18381259 PRKCA protein kinase C alpha gene PW:0000659 syndecan signaling pathway ISO RGD:737062 W RGD:9068941 20211008 PID PID:200134 18381259 PRKCA protein kinase C alpha gene PW:0000840 protein kinase C (PKC) signaling pathway ISO RGD:737062 W RGD:9068941 20211008 RGD PMID:19934406|REF_RGD_ID:5131489 18381259 PRKCA protein kinase C alpha gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:737062 W RGD:9068941 20211008 SMPDB SMP:00358 18381313 DCTN4 dynactin subunit 4 gene PW:0002061 mitochondria transport pathway ISO RGD:736897 W RGD:9068941 20211008 RGD PMID:15473859|REF_RGD_ID:10402155 18381480 CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 gene PW:0002139 intermembrane space assembly pathway of mitochondrial protein import ISO RGD:1321831 W RGD:9068941 20211008 RGD PMID:26214018|REF_RGD_ID:10412663 18381531 NOTCH3 notch receptor 3 gene PW:0000204 Notch signaling pathway ISO RGD:620761 W RGD:9068941 20211008 RGD PMID:11971902|PMID:15247148|REF_RGD_ID:2306423|REF_RGD_ID:625426 18381531 NOTCH3 notch receptor 3 gene PW:0000204 Notch signaling pathway ISO RGD:732750 W RGD:9068941 20211008 PID PID:200015 18381531 NOTCH3 notch receptor 3 gene PW:0000204 Notch signaling pathway ISO RGD:732750 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18381531 NOTCH3 notch receptor 3 gene PW:0000340 altered Notch signaling pathway involving the main players ISO RGD:732750 W RGD:9068941 20211008 RGD Mutations are predominantly found in the EGF repeats and clustered within the first five PMID:9388399|REF_RGD_ID:1334441 18381531 NOTCH3 notch receptor 3 gene PW:0000346 CADASIL pathway ISO RGD:732750 W RGD:9068941 20211008 RGD Mutations are predominantly found in the EGF repeats and clustered within the first five PMID:9388399|REF_RGD_ID:1334441 18381791 DVL1 dishevelled segment polarity protein 1 gene PW:0000008 Wnt signaling pathway ISO RGD:733043 W RGD:9068941 20211008 RGD 18381791 DVL1 dishevelled segment polarity protein 1 gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:733043 W RGD:9068941 20211008 RGD PMID:15608632|REF_RGD_ID:1581694 18381791 DVL1 dishevelled segment polarity protein 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:620632 W RGD:9068941 20211008 RGD PMID:16478782|REF_RGD_ID:1581696 18381791 DVL1 dishevelled segment polarity protein 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:733042 W RGD:9068941 20211008 PID PID:200077 18381791 DVL1 dishevelled segment polarity protein 1 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:733042 W RGD:9068941 20211008 PID PID:200020 18381819 UBE2D2 ubiquitin conjugating enzyme E2 D2 gene PW:0000144 ubiquitin/proteasome degradation pathway ISO RGD:1591897 W RGD:9068941 20211008 RGD PMID:8754804|REF_RGD_ID:69394 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00075 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00096 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00086 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001524 paracetamol drug pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00710 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001532 prostaglandin biosynthetic pathway ISO RGD:737546 W RGD:9068941 20211008 RGD PMID:12432932|REF_RGD_ID:8552774 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:737546 W RGD:9068941 20211008 RGD PMID:19442138|PMID:21048526|REF_RGD_ID:10395261|REF_RGD_ID:10395262 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00650 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001612 Segawa syndrome pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00490 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00083 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001665 antipyrine drug pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00692 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00116 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00704 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00706 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00094 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00077 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00120 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00114 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00106 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00109 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00098 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00085 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00084 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00289 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00093 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002105 dopa responsive dystonia pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00486 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00696 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00104 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00104 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00700 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00709 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00708 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00353 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00705 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00697 18381964 LOC103218526 carbonyl reductase [NADPH] 1 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:737546 W RGD:9068941 20211008 SMPDB SMP:00698 18381993 DCP1B decapping mRNA 1B gene PW:0000808 microRNA pathway ISO RGD:1348381 W RGD:9068941 20211008 RGD PMID:24352420|REF_RGD_ID:9850104 18382028 ARID1A AT-rich interaction domain 1A gene PW:0000626 pancreatic cancer pathway ISO RGD:1321437 W RGD:9068941 20211008 RGD PMID:23355908|REF_RGD_ID:8694154 18382028 ARID1A AT-rich interaction domain 1A gene PW:0001406 SWI/SNF family mediated chromatin remodeling pathway ISO RGD:1321437 W RGD:9068941 20211008 RGD PMID:21358755|PMID:23355908|REF_RGD_ID:8694154|REF_RGD_ID:9495920 18382028 ARID1A AT-rich interaction domain 1A gene PW:0001554 altered SWI/SNF family mediated chromatin remodeling pathway ISO RGD:1321437 W RGD:9068941 20211008 RGD PMID:23355908|REF_RGD_ID:8694154 18382172 NR1H4 nuclear receptor subfamily 1 group H member 4 gene PW:0001093 bile acid signaling pathway ISO RGD:734103 W RGD:9068941 20211008 RGD PMID:28774887|REF_RGD_ID:15045601 18382344 RPGR retinitis pigmentosa GTPase regulator gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1352855 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18382363 RPS11 ribosomal protein S11 gene PW:0000101 translation pathway ISO RGD:733888 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18382363 RPS11 ribosomal protein S11 gene PW:0001066 ribosome biogenesis pathway ISO RGD:733888 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18382479 KAT5 lysine acetyltransferase 5 gene PW:0000718 p53 signaling pathway ISO RGD:732354 W RGD:9068941 20211008 PID PID:200206 18382479 KAT5 lysine acetyltransferase 5 gene PW:0000718 p53 signaling pathway ISO RGD:732354 W RGD:9068941 20211008 RGD PMID:19450511|PMID:20679336|REF_RGD_ID:2316155|REF_RGD_ID:8662965 18382479 KAT5 lysine acetyltransferase 5 gene PW:0001338 histone modification pathway ISO RGD:732354 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18382479 KAT5 lysine acetyltransferase 5 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:732354 W RGD:9068941 20211008 RGD PMID:21533982|PMID:23532176|REF_RGD_ID:8661225|REF_RGD_ID:8661232 18382479 KAT5 lysine acetyltransferase 5 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:732354 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18382532 BPGM bisphosphoglycerate mutase gene PW:0000640 glycolysis pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00040 18382532 BPGM bisphosphoglycerate mutase gene PW:0000641 gluconeogenesis pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00128 18382532 BPGM bisphosphoglycerate mutase gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00563 18382532 BPGM bisphosphoglycerate mutase gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18382532 BPGM bisphosphoglycerate mutase gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00573 18382532 BPGM bisphosphoglycerate mutase gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00531 18382532 BPGM bisphosphoglycerate mutase gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00562 18382532 BPGM bisphosphoglycerate mutase gene PW:0002360 Fanconi syndrome pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00572 18382532 BPGM bisphosphoglycerate mutase gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:1605438 W RGD:9068941 20211008 SMPDB SMP:00560 18382822 STRADA STE20 related adaptor alpha gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1551270 W RGD:9068941 20211008 RGD PMID:15509864|REF_RGD_ID:1600678 18382822 STRADA STE20 related adaptor alpha gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1606991 W RGD:9068941 20211008 RGD PMID:15509864|REF_RGD_ID:1600678 18382822 STRADA STE20 related adaptor alpha gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:727905 W RGD:9068941 20211008 RGD PMID:14511394|PMID:15509864|REF_RGD_ID:1600678|REF_RGD_ID:1600691 18382871 WNT1 Wnt family member 1 gene PW:0000008 Wnt signaling pathway ISO RGD:11491 W RGD:9068941 20211008 RGD PMID:9353119|REF_RGD_ID:13208953 18382871 WNT1 Wnt family member 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1344355 W RGD:9068941 20211008 RGD PMID:18765832|PMID:20848229|REF_RGD_ID:13209023|REF_RGD_ID:2313743 18382957 BAZ1A bromodomain adjacent to zinc finger domain 1A gene PW:0001407 ISWI family mediated chromatin remodeling pathway ISO RGD:1314679 W RGD:9068941 20211008 RGD PMID:21358755|REF_RGD_ID:9495920 18383019 DHFR dihydrofolate reductase gene PW:0000032 pyrimidine metabolic pathway ISO RGD:2500 W RGD:9068941 20211008 RGD PMID:11502523|REF_RGD_ID:1298877 18383019 DHFR dihydrofolate reductase gene PW:0000140 folate metabolic pathway ISO RGD:2500 W RGD:9068941 20211008 RGD PMID:11502523|REF_RGD_ID:1298877 18383019 DHFR dihydrofolate reductase gene PW:0000140 folate metabolic pathway ISO RGD:736871 W RGD:9068941 20211008 SMPDB SMP:00053 18383019 DHFR dihydrofolate reductase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:2500 W RGD:9068941 20211008 RGD PMID:11502523|REF_RGD_ID:1298877 18383019 DHFR dihydrofolate reductase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:736871 W RGD:9068941 20211008 RGD PMID:22332074|REF_RGD_ID:7242561 18383019 DHFR dihydrofolate reductase gene PW:0000932 methotrexate pharmacodynamics pathway ISO RGD:736871 W RGD:9068941 20211008 SMPDB SMP:00432 18383019 DHFR dihydrofolate reductase gene PW:0001207 folate cycle metabolic pathway ISO RGD:736871 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18383019 DHFR dihydrofolate reductase gene PW:0001208 altered folate cycle metabolic pathway ISO RGD:736871 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18383019 DHFR dihydrofolate reductase gene PW:0001612 Segawa syndrome pathway ISO RGD:736871 W RGD:9068941 20211008 SMPDB SMP:00490 18383019 DHFR dihydrofolate reductase gene PW:0002105 dopa responsive dystonia pathway ISO RGD:736871 W RGD:9068941 20211008 SMPDB SMP:00486 18383019 DHFR dihydrofolate reductase gene PW:0002236 hereditary folate malabsorption pathway ISO RGD:736871 W RGD:9068941 20211008 SMPDB SMP:00724 18383165 TAF13 TATA-box binding protein associated factor 13 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1313406 W RGD:9068941 20211008 RGD PMID:23146842|REF_RGD_ID:9681723 18383200 SPTBN1 spectrin beta, non-erythrocytic 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1351608 W RGD:9068941 20211008 PID PID:200227 18383310 LIMS2 LIM zinc finger domain containing 2 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1313204 W RGD:9068941 20211008 RGD PMID:16493410|REF_RGD_ID:2300344 18383336 IRF8 interferon regulatory factor 8 gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1351360 W RGD:9068941 20211008 PID PID:200019 18383531 MC5R melanocortin 5 receptor gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:732421 W RGD:9068941 20211008 RGD PMID:20852827|REF_RGD_ID:5144213 18383531 MC5R melanocortin 5 receptor gene PW:0000365 melanocortin system pathway ISO RGD:10886 W RGD:9068941 20211008 RGD PMID:9512481|REF_RGD_ID:1626223 18383531 MC5R melanocortin 5 receptor gene PW:0000365 melanocortin system pathway ISO RGD:732421 W RGD:9068941 20211008 RGD PMID:20852827|REF_RGD_ID:5144213 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0000050 arginine and proline metabolic pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00020 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0000076 urea cycle pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00059 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0001806 ornithine carbamoyltransferase deficiency pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00205 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0001807 gyrate atrophy pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00363 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0001931 hyperprolinemia type I pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00361 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0001932 hyperprolinemia type II pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00360 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002143 citrullinemia pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00001 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002145 argininosuccinic aciduria pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00003 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002181 prolidase deficiency pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00207 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002220 carbamoyl phosphate synthetase I deficiency pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00002 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002290 hyperargininemia pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00357 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002359 AGAT deficiency pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18383680 SLC25A15 solute carrier family 25 member 15 gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:1322973 W RGD:9068941 20211008 SMPDB SMP:00506 18383692 TNKS2 tankyrase 2 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1312811 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18383844 RPL15 ribosomal protein L15 gene PW:0000101 translation pathway ISO RGD:736821 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18383844 RPL15 ribosomal protein L15 gene PW:0001066 ribosome biogenesis pathway ISO RGD:736821 W RGD:9068941 20211008 RGD PMID:23636399|PMID:25346433|REF_RGD_ID:10002762|REF_RGD_ID:9999448 18383899 GTF2E1 general transcription factor IIE subunit 1 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1315703 W RGD:9068941 20211008 RGD PMID:24120742|REF_RGD_ID:9681721 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00296 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00379 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00665 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00376 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00375 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00659 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00660 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00323 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00307 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00324 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00380 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00381 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00382 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00366 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00302 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00378 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00332 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00331 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00301 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00325 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00359 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002134 bupranolol drug pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00670 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00670 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00300 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00299 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00296 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00298 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00305 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00303 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00306 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00326 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00666 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00327 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00329 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00662 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00663 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00328 18383952 KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:736969 W RGD:9068941 20211008 SMPDB SMP:00367 18384025 PTDSS2 phosphatidylserine synthase 2 gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:1317384 W RGD:9068941 20211008 SMPDB SMP:00025 18384085 EIF4A1 eukaryotic translation initiation factor 4A1 gene PW:0000180 mTOR signaling pathway ISO RGD:1354204 W RGD:9068941 20211008 PID PID:200096 18384085 EIF4A1 eukaryotic translation initiation factor 4A1 gene PW:0000580 translation initiation pathway ISO RGD:1354204 W RGD:9068941 20211008 RGD PMID:21427765|PMID:24450646|REF_RGD_ID:10044020|REF_RGD_ID:10044021 18384182 TREX1 three prime repair exonuclease 1 gene PW:0000098 DNA replication pathway ISO RGD:1323748 W RGD:9068941 20211008 RGD PMID:11721054|REF_RGD_ID:1580482 18384182 TREX1 three prime repair exonuclease 1 gene PW:0000384 G2/M DNA damage checkpoint pathway ISO RGD:1323748 W RGD:9068941 20211008 RGD PMID:11721054|REF_RGD_ID:1580482 18384306 MC3R melanocortin 3 receptor gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:1345990 W RGD:9068941 20211008 RGD PMID:20852827|REF_RGD_ID:5144213 18384306 MC3R melanocortin 3 receptor gene PW:0000365 melanocortin system pathway ISO RGD:1345990 W RGD:9068941 20211008 RGD PMID:20852827|REF_RGD_ID:5144213 18384306 MC3R melanocortin 3 receptor gene PW:0000365 melanocortin system pathway ISO RGD:3056 W RGD:9068941 20211008 RGD PMID:8415620|REF_RGD_ID:69884 18384603 UGCG UDP-glucose ceramide glucosyltransferase gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1349188 W RGD:9068941 20211008 SMPDB SMP:00034 18384603 UGCG UDP-glucose ceramide glucosyltransferase gene PW:0001454 Gaucher's disease pathway ISO RGD:1349188 W RGD:9068941 20211008 SMPDB SMP:00349 18384603 UGCG UDP-glucose ceramide glucosyltransferase gene PW:0002021 Krabbe disease pathway ISO RGD:1349188 W RGD:9068941 20211008 SMPDB SMP:00348 18384603 UGCG UDP-glucose ceramide glucosyltransferase gene PW:0002103 Fabry disease pathway ISO RGD:1349188 W RGD:9068941 20211008 SMPDB SMP:00525 18384603 UGCG UDP-glucose ceramide glucosyltransferase gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1349188 W RGD:9068941 20211008 SMPDB SMP:00347 18384677 NAT2 N-acetyltransferase 2 gene PW:0002318 caffeine pharmacokinetics pathway ISO RGD:732527 W RGD:9068941 20211008 SMPDB SMP:00028 18384769 CDC14B cell division cycle 14B gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1322476 W RGD:9068941 20211008 RGD pol II carboxyl-terminal domain (CTD) PMID:22622228|PMID:23837720|REF_RGD_ID:9681737|REF_RGD_ID:9681738 18384837 EDC3 enhancer of mRNA decapping 3 gene PW:0000808 microRNA pathway ISO RGD:1604794 W RGD:9068941 20211008 RGD PMID:24352420|REF_RGD_ID:9850104 18384862 MRGBP MRG domain binding protein gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1318486 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18384871 LEF1 lymphoid enhancer binding factor 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:735736 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18384871 LEF1 lymphoid enhancer binding factor 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:735737 W RGD:9068941 20211008 RGD PMID:10528152|REF_RGD_ID:2301908 18384906 LCT lactase gene PW:0000042 galactose metabolic pathway ISO RGD:1344800 W RGD:9068941 20211008 SMPDB SMP:00043 18384906 LCT lactase gene PW:0001364 lactose degradation pathway ISO RGD:1344800 W RGD:9068941 20211008 SMPDB SMP:00457 18384906 LCT lactase gene PW:0002092 galactosemia pathway ISO RGD:1344800 W RGD:9068941 20211008 SMPDB SMP:00182 18385224 FBL fibrillarin gene PW:0001066 ribosome biogenesis pathway ISO RGD:1313628 W RGD:9068941 20211008 RGD PMID:22065625|REF_RGD_ID:9999451 18385573 LOC103233227 ribosomal protein S6 kinase alpha-4 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:1316377 W RGD:9068941 20211008 RGD PMID:16421520|REF_RGD_ID:2315047 18385573 LOC103233227 ribosomal protein S6 kinase alpha-4 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1316377 W RGD:9068941 20211008 RGD PMID:16421520|REF_RGD_ID:2315047 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000209 Jak-Stat signaling pathway ISO RGD:11351 W RGD:9068941 20211008 RGD PMID:17312100|REF_RGD_ID:1625126 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000209 Jak-Stat signaling pathway ISO RGD:3773 W RGD:9068941 20211008 RGD PMID:11064147|REF_RGD_ID:1624963 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000209 Jak-Stat signaling pathway ISO RGD:737523 W RGD:9068941 20211008 RGD PMID:12039028|PMID:17312100|REF_RGD_ID:1357935|REF_RGD_ID:1625126 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200149 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000907 interleukin-2 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200098 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000912 interleukin-4 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200022 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000914 interleukin-12 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200045 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000915 interleukin-23 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200154 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000916 interleukin-27 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200028 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000968 interleukin-3 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200145 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000969 interleukin-5 signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200107 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200019 18385617 STAT5A signal transducer and activator of transcription 5A gene PW:0000987 erythropoietin signaling pathway ISO RGD:737523 W RGD:9068941 20211008 PID PID:200183 18385812 CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 gene PW:0001139 calcium transport pathway ISO RGD:735859 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18385812 CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:735859 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18385839 SRSF9 serine and arginine rich splicing factor 9 gene PW:0001073 spliceosome pathway ISO RGD:1319864 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18385870 PCDH15 protocadherin related 15 gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1353280 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18385870 PCDH15 protocadherin related 15 gene PW:0001503 auditory mechanotransduction pathway ISO RGD:1353280 W RGD:9068941 20211008 RGD PMID:19804752|PMID:22177415|REF_RGD_ID:8547667|REF_RGD_ID:8547671 18385993 LOC103242767 C-C motif chemokine 3 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:735784 W RGD:9068941 20211008 PID PID:200045 18386174 NFIA nuclear factor I A gene PW:0000958 forkhead class A signaling pathway ISO RGD:69144 W RGD:9068941 20211008 PID PID:200226 18386212 C4BPB complement component 4 binding protein beta gene PW:0000958 forkhead class A signaling pathway ISO RGD:736875 W RGD:9068941 20211008 PID PID:200226 18386325 RPS3 ribosomal protein S3 gene PW:0000101 translation pathway ISO RGD:736568 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18386325 RPS3 ribosomal protein S3 gene PW:0001066 ribosome biogenesis pathway ISO RGD:736568 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18386510 RPS21 ribosomal protein S21 gene PW:0000101 translation pathway ISO RGD:1348628 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18386510 RPS21 ribosomal protein S21 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1348628 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18386541 PRDM16 PR/SET domain 16 gene PW:0001338 histone modification pathway ISO RGD:1353101 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18386608 CTBP1 C-terminal binding protein 1 gene PW:0000204 Notch signaling pathway ISO RGD:732729 W RGD:9068941 20211008 PID PID:200015 18386687 EEF2K eukaryotic elongation factor 2 kinase gene PW:0000180 mTOR signaling pathway ISO RGD:1351780 W RGD:9068941 20211008 PID PID:200096 18386729 NSD3 nuclear receptor binding SET domain protein 3 gene PW:0001338 histone modification pathway ISO RGD:1319069 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18386778 CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 gene PW:0002061 mitochondria transport pathway ISO RGD:1314786 W RGD:9068941 20211008 RGD PMID:15473859|REF_RGD_ID:10402155 18386829 IGFBP3 insulin like growth factor binding protein 3 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:736042 W RGD:9068941 20211008 RGD PMID:15862547|REF_RGD_ID:1626333 18386871 SKIL SKI like proto-oncogene gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1314830 W RGD:9068941 20211008 PID PID:200227 18386895 LAMA1 laminin subunit alpha 1 gene PW:0000658 glypican signaling pathway ISO RGD:1316264 W RGD:9068941 20211008 PID PID:200026 18386895 LAMA1 laminin subunit alpha 1 gene PW:0000659 syndecan signaling pathway ISO RGD:1316264 W RGD:9068941 20211008 PID PID:200134|PID:200192 18386991 TRAF5 TNF receptor associated factor 5 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1605425 W RGD:9068941 20211008 RGD PMID:23085193|REF_RGD_ID:7800730 18387118 DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit gene PW:0000180 mTOR signaling pathway ISO RGD:1323042 W RGD:9068941 20211008 RGD PMID:24698685|REF_RGD_ID:11535043 18387371 PARP11 poly(ADP-ribose) polymerase family member 11 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1344916 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18387396 NOS3 nitric oxide synthase 3 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:735618 W RGD:9068941 20211008 PID PID:200188 18387396 NOS3 nitric oxide synthase 3 gene PW:0000565 eicosanoid signaling pathway ISO RGD:735618 W RGD:9068941 20211008 PID PID:200082 18387396 NOS3 nitric oxide synthase 3 gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:735618 W RGD:9068941 20211008 RGD PMID:19442138|REF_RGD_ID:10395262 18387396 NOS3 nitric oxide synthase 3 gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:735618 W RGD:9068941 20211008 SMPDB SMP:00650 18387535 MICOS10 mitochondrial contact site and cristae organizing system subunit 10 gene PW:0001962 mitochondrial protein import pathway contributes_to ISO RGD:1603802 W RGD:9068941 20211008 RGD PMID:23109542|REF_RGD_ID:10412671 18387660 FGFR1 fibroblast growth factor receptor 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:732290 W RGD:9068941 20211008 PID PID:200220 18387660 FGFR1 fibroblast growth factor receptor 1 gene PW:0000658 glypican signaling pathway ISO RGD:732290 W RGD:9068941 20211008 PID PID:200026 18387660 FGFR1 fibroblast growth factor receptor 1 gene PW:0000659 syndecan signaling pathway ISO RGD:732290 W RGD:9068941 20211008 PID PID:200134 18387660 FGFR1 fibroblast growth factor receptor 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:732290 W RGD:9068941 20211008 PID PID:200209 18387660 FGFR1 fibroblast growth factor receptor 1 gene PW:0001439 cerium oxide nanoparticle response pathway ISO RGD:732290 W RGD:9068941 20211008 RGD PMID:23478040|REF_RGD_ID:7364779 18387958 SRD5A1 steroid 5 alpha-reductase 1 gene PW:0000778 testosterone biosynthetic pathway ISO RGD:736446 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18388049 ARF6 ARF GTPase 6 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:734181 W RGD:9068941 20211008 PID PID:200116 18388049 ARF6 ARF GTPase 6 gene PW:0000992 E-cadherin signaling pathway ISO RGD:734181 W RGD:9068941 20211008 PID PID:200124|PID:200182 18388098 HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 gene PW:0000778 testosterone biosynthetic pathway ISO RGD:1353008 W RGD:9068941 20211008 RGD PMID:15583024|REF_RGD_ID:4889549 18388098 HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 gene PW:0000781 estradiol biosynthetic pathway ISO RGD:1353008 W RGD:9068941 20211008 RGD PMID:15583024|REF_RGD_ID:4889549 18388146 ASF1B anti-silencing function 1B histone chaperone gene PW:0001338 histone modification pathway ISO RGD:1312634 W RGD:9068941 20211008 RGD PMID:23288364|REF_RGD_ID:9068945 18388516 PDE6A phosphodiesterase 6A gene PW:0000962 visual phototransduction pathway ISO RGD:1315676 W RGD:9068941 20211008 RGD PMID:15224133|REF_RGD_ID:6893540 18388516 PDE6A phosphodiesterase 6A gene PW:0001495 altered visual phototransduction pathway ISO RGD:1315676 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18388516 PDE6A phosphodiesterase 6A gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1315676 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18388542 RBP3 retinol binding protein 3 gene PW:0001005 retinoid cycle metabolic pathway ISO RGD:735986 W RGD:9068941 20211008 RGD PMID:21447403|REF_RGD_ID:6893650 18388542 RBP3 retinol binding protein 3 gene PW:0001497 retinitis pigmentosa pathway ISO RGD:735986 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18388542 RBP3 retinol binding protein 3 gene PW:0001498 altered retinoid cycle metabolic pathway ISO RGD:735986 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18388579 SLC27A5 solute carrier family 27 member 5 gene PW:0000039 bile acid biosynthetic pathway ISO RGD:1349953 W RGD:9068941 20211008 SMPDB SMP:00035 18388579 SLC27A5 solute carrier family 27 member 5 gene PW:0001415 Zellweger syndrome pathway ISO RGD:1349953 W RGD:9068941 20211008 SMPDB SMP:00316 18388579 SLC27A5 solute carrier family 27 member 5 gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:1349953 W RGD:9068941 20211008 SMPDB SMP:00315 18388579 SLC27A5 solute carrier family 27 member 5 gene PW:0002302 familial hypercholanemia pathway ISO RGD:1349953 W RGD:9068941 20211008 SMPDB SMP:00317 18388579 SLC27A5 solute carrier family 27 member 5 gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:1349953 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18389062 KIFC3 kinesin family member C3 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1317029 W RGD:9068941 20211008 PID PID:200182 18389108 LOC103239275 serum amyloid A-4 protein gene PW:0000010 lipid metabolic pathway ISO RGD:1316532 W RGD:9068941 20211008 RGD PMID:7775864|REF_RGD_ID:1579981 18389126 SOD2 superoxide dismutase 2 gene PW:0000021 hypertension pathway ISO RGD:3732 W RGD:9068941 20211008 RGD PMID:16716903|REF_RGD_ID:1580833 18389126 SOD2 superoxide dismutase 2 gene PW:0000021 hypertension pathway ISO RGD:730872 W RGD:9068941 20211008 RGD PMID:16716903|REF_RGD_ID:1580833 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:61888 W RGD:9068941 20211008 RGD PMID:17310240|REF_RGD_ID:1626216 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000143 insulin signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 SMPDB SMP:00391 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000180 mTOR signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200096 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200188 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200149 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000506 endothelin signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200005 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200098 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000961 ceramide signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200119 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 PID PID:200019 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0000998 adenosine signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18389136 MAP2K2 mitogen-activated protein kinase kinase 2 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:1343460 W RGD:9068941 20211008 SMPDB SMP:00358 18389781 COL4A3 collagen type IV alpha 3 chain gene PW:0000659 syndecan signaling pathway ISO RGD:736518 W RGD:9068941 20211008 PID PID:200156 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0000076 urea cycle pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00059 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0001806 ornithine carbamoyltransferase deficiency pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00205 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0002143 citrullinemia pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00001 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0002145 argininosuccinic aciduria pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00003 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0002220 carbamoyl phosphate synthetase I deficiency pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00002 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0002290 hyperargininemia pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00357 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:1313056 W RGD:9068941 20211008 RGD PMID:16368075|PMID:18020963|REF_RGD_ID:11251688|REF_RGD_ID:5129954 18389891 SLC25A12 solute carrier family 25 member 12 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:1313056 W RGD:9068941 20211008 SMPDB SMP:00129 18389922 STAT6 signal transducer and activator of transcription 6 gene PW:0000209 Jak-Stat signaling pathway ISO RGD:1319194 W RGD:9068941 20211008 RGD PMID:12039028|PMID:17312100|REF_RGD_ID:1357935|REF_RGD_ID:1625126 18389922 STAT6 signal transducer and activator of transcription 6 gene PW:0000209 Jak-Stat signaling pathway ISO RGD:1319195 W RGD:9068941 20211008 RGD PMID:17312100|REF_RGD_ID:1625126 18389922 STAT6 signal transducer and activator of transcription 6 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1319194 W RGD:9068941 20211008 PID PID:200022 18389922 STAT6 signal transducer and activator of transcription 6 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1319194 W RGD:9068941 20211008 PID PID:200045 18390097 DGAT1 diacylglycerol O-acyltransferase 1 gene PW:0000141 retinol metabolic pathway ISO RGD:731052 W RGD:9068941 20211008 SMPDB SMP:00074 18390097 DGAT1 diacylglycerol O-acyltransferase 1 gene PW:0001585 vitamin A deficiency pathway ISO RGD:731052 W RGD:9068941 20211008 SMPDB SMP:00336 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0000065 butanoate metabolic pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00073 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0000073 lysine degradation pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00037 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00480|SMP:00481|SMP:00482 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0000738 fatty acid beta degradation pathway ISO RGD:69321 W RGD:9068941 20211008 RGD PMID:17491019|REF_RGD_ID:2302227 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0000958 forkhead class A signaling pathway ISO RGD:1351201 W RGD:9068941 20211008 PID PID:200087 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0001668 3-hydroxyacyl-CoA dehydrogenase deficiency pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00568 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0001703 saccharopinuria pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00239|SMP:00528 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0001936 hyperlysinemia pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00527 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0002204 2-aminoadipic 2-oxoadipic aciduria pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00719 18390169 HADH hydroxyacyl-CoA dehydrogenase gene PW:0002306 glutaric aciduria type I pathway ISO RGD:1351201 W RGD:9068941 20211008 SMPDB SMP:00186 18390222 FZD2 frizzled class receptor 2 gene PW:0000008 Wnt signaling pathway ISO RGD:732092 W RGD:9068941 20211008 RGD 18390222 FZD2 frizzled class receptor 2 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:732091 W RGD:9068941 20211008 PID PID:200020 18390227 PDE1B phosphodiesterase 1B gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:735556 W RGD:9068941 20211008 RGD PMID:17376027|REF_RGD_ID:2312479 18390580 GUK1 guanylate kinase 1 gene PW:0000031 purine metabolic pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00050 18390580 GUK1 guanylate kinase 1 gene PW:0001590 xanthinuria pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00220 18390580 GUK1 guanylate kinase 1 gene PW:0001591 xanthinuria type I pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00512 18390580 GUK1 guanylate kinase 1 gene PW:0001592 xanthinuria type II pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00513 18390580 GUK1 guanylate kinase 1 gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00210 18390580 GUK1 guanylate kinase 1 gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00537 18390580 GUK1 guanylate kinase 1 gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00203 18390580 GUK1 guanylate kinase 1 gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00364 18390580 GUK1 guanylate kinase 1 gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00365 18390580 GUK1 guanylate kinase 1 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00428 18390580 GUK1 guanylate kinase 1 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00427 18390580 GUK1 guanylate kinase 1 gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00167 18390580 GUK1 guanylate kinase 1 gene PW:0002294 AICA-ribosuria pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00168 18390580 GUK1 guanylate kinase 1 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00430 18390580 GUK1 guanylate kinase 1 gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:1320084 W RGD:9068941 20211008 SMPDB SMP:00535 18390667 GALC galactosylceramidase gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1347926 W RGD:9068941 20211008 SMPDB SMP:00034 18390667 GALC galactosylceramidase gene PW:0001454 Gaucher's disease pathway ISO RGD:1347926 W RGD:9068941 20211008 SMPDB SMP:00349 18390667 GALC galactosylceramidase gene PW:0002021 Krabbe disease pathway ISO RGD:1347926 W RGD:9068941 20211008 SMPDB SMP:00348 18390667 GALC galactosylceramidase gene PW:0002103 Fabry disease pathway ISO RGD:1347926 W RGD:9068941 20211008 SMPDB SMP:00525 18390667 GALC galactosylceramidase gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1347926 W RGD:9068941 20211008 SMPDB SMP:00347 18391190 PPIH peptidylprolyl isomerase H gene PW:0001073 spliceosome pathway ISO RGD:1347300 W RGD:9068941 20211008 RGD PMID:18544344|REF_RGD_ID:9686376 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00671 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00431 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00413 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00402 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00686 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00687 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00691 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00408 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00399 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001986 imipramine pharmacokinetics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00625 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00422 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00426 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00415 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00425 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002089 desipramine pharmacokinetics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00626 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00423 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00424 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00684 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00393 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00401 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00404 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00688 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00416 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00397 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00409 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00410 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00411 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00412 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002474 venlafaxine pharmacokinetics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00636 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00394 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00681 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00395 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00398 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00400 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00677 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00673 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00407 18391375 SLC6A2 solute carrier family 6 member 2 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:731947 W RGD:9068941 20211008 SMPDB SMP:00675 18391424 CUL3 cullin 3 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1317824 W RGD:9068941 20211008 PID PID:200077 18391424 CUL3 cullin 3 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1317824 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18391424 CUL3 cullin 3 gene PW:0000415 proteasome degradation pathway involving cullin-dependent ubiquitin ligases ISO RGD:1317824 W RGD:9068941 20211008 RGD PMID:15601839|REF_RGD_ID:1559279 18391676 WDR33 WD repeat domain 33 gene PW:0001332 RNA polymerase II transcription termination pathway ISO RGD:1319455 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18391676 WDR33 WD repeat domain 33 gene PW:0001579 3'-end pre-mRNA processing pathway ISO RGD:1319455 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18391766 RIOK2 RIO kinase 2 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1323125 W RGD:9068941 20211008 RGD PMID:24424021|REF_RGD_ID:10002751 18391783 ITGA4 integrin subunit alpha 4 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1348031 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18391783 ITGA4 integrin subunit alpha 4 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1593249 W RGD:9068941 20211008 RGD PMID:11782963|REF_RGD_ID:1302879 18391783 ITGA4 integrin subunit alpha 4 gene PW:0000295 altered integrin mediated signaling pathway ISO RGD:1348031 W RGD:9068941 20211008 RGD PMID:18772397|REF_RGD_ID:5490966 18391783 ITGA4 integrin subunit alpha 4 gene PW:0000295 altered integrin mediated signaling pathway ISO RGD:1593249 W RGD:9068941 20211008 RGD PMID:11782963|REF_RGD_ID:1302879 18391783 ITGA4 integrin subunit alpha 4 gene PW:0000626 pancreatic cancer pathway ISO RGD:1348031 W RGD:9068941 20211008 RGD PMID:18772397|REF_RGD_ID:5490966 18391840 KIF1B kinesin family member 1B gene PW:0002061 mitochondria transport pathway ISO RGD:732615 W RGD:9068941 20211008 RGD PMID:25612908|REF_RGD_ID:10402141 18391964 CD38 CD38 molecule gene PW:0002583 ADP-ribosylation pathway, cyclic ribosylation ISO RGD:735841 W RGD:9068941 20211008 RGD PMID:23576305|REF_RGD_ID:11250406 18392071 SLC29A2 solute carrier family 29 member 2 gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:733577 W RGD:9068941 20211008 SMPDB SMP:00609 18392071 SLC29A2 solute carrier family 29 member 2 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:733577 W RGD:9068941 20211008 SMPDB SMP:00428 18392071 SLC29A2 solute carrier family 29 member 2 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:733577 W RGD:9068941 20211008 SMPDB SMP:00427 18392071 SLC29A2 solute carrier family 29 member 2 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:733577 W RGD:9068941 20211008 SMPDB SMP:00430 18392106 PPP3CA protein phosphatase 3 catalytic subunit alpha gene PW:0000315 calcineurin signaling pathway ISO RGD:730900 W RGD:9068941 20211008 RGD PMID:15336966|REF_RGD_ID:1579951 18392106 PPP3CA protein phosphatase 3 catalytic subunit alpha gene PW:0000394 dopamine signaling pathway ISO RGD:730900 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18392106 PPP3CA protein phosphatase 3 catalytic subunit alpha gene PW:0000914 interleukin-12 signaling pathway ISO RGD:730900 W RGD:9068941 20211008 PID PID:200045 18392219 DRD1 dopamine receptor D1 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:70828 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18392219 DRD1 dopamine receptor D1 gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:70828 W RGD:9068941 20211008 RGD D1-D2 heterodimer PMID:25671228|REF_RGD_ID:11041142 18392219 DRD1 dopamine receptor D1 gene PW:0000394 dopamine signaling pathway ISO RGD:2518 W RGD:9068941 20211008 RGD PMID:17314300|REF_RGD_ID:1625010 18392219 DRD1 dopamine receptor D1 gene PW:0000394 dopamine signaling pathway ISO RGD:70828 W RGD:9068941 20211008 RGD heterodimer coupled to Galphaq PMID:25671228|REF_RGD_ID:11041142 18392219 DRD1 dopamine receptor D1 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:70828 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18392219 DRD1 dopamine receptor D1 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00308 18392219 DRD1 dopamine receptor D1 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00671 18392219 DRD1 dopamine receptor D1 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18392219 DRD1 dopamine receptor D1 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00431 18392219 DRD1 dopamine receptor D1 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00413 18392219 DRD1 dopamine receptor D1 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00402 18392219 DRD1 dopamine receptor D1 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00686 18392219 DRD1 dopamine receptor D1 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00687 18392219 DRD1 dopamine receptor D1 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00691 18392219 DRD1 dopamine receptor D1 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00408 18392219 DRD1 dopamine receptor D1 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00399 18392219 DRD1 dopamine receptor D1 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00422 18392219 DRD1 dopamine receptor D1 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00426 18392219 DRD1 dopamine receptor D1 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00415 18392219 DRD1 dopamine receptor D1 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00425 18392219 DRD1 dopamine receptor D1 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00423 18392219 DRD1 dopamine receptor D1 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00424 18392219 DRD1 dopamine receptor D1 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00684 18392219 DRD1 dopamine receptor D1 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00393 18392219 DRD1 dopamine receptor D1 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00401 18392219 DRD1 dopamine receptor D1 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00404 18392219 DRD1 dopamine receptor D1 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00688 18392219 DRD1 dopamine receptor D1 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00416 18392219 DRD1 dopamine receptor D1 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00397 18392219 DRD1 dopamine receptor D1 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00409 18392219 DRD1 dopamine receptor D1 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00410 18392219 DRD1 dopamine receptor D1 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00411 18392219 DRD1 dopamine receptor D1 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00412 18392219 DRD1 dopamine receptor D1 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00394 18392219 DRD1 dopamine receptor D1 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00681 18392219 DRD1 dopamine receptor D1 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00395 18392219 DRD1 dopamine receptor D1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00398 18392219 DRD1 dopamine receptor D1 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00400 18392219 DRD1 dopamine receptor D1 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00677 18392219 DRD1 dopamine receptor D1 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00673 18392219 DRD1 dopamine receptor D1 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00407 18392219 DRD1 dopamine receptor D1 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:70828 W RGD:9068941 20211008 SMPDB SMP:00675 18392312 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:735560 W RGD:9068941 20211008 PID PID:200202 18392312 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 gene PW:0000640 glycolysis pathway ISO RGD:619776 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18392312 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 gene PW:0000640 glycolysis pathway ISO RGD:735560 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18392355 UHRF2 ubiquitin like with PHD and ring finger domains 2 gene PW:0001340 DNA modification pathway ISO RGD:1320632 W RGD:9068941 20211008 RGD PMID:23324617|REF_RGD_ID:8695954 18392399 IL15RA interleukin 15 receptor subunit alpha gene PW:0000209 Jak-Stat signaling pathway ISO RGD:1305149 W RGD:9068941 20211008 RGD PMID:19747902|REF_RGD_ID:5001122 18392477 IL6 interleukin 6 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1352582 W RGD:9068941 20211008 PID PID:200146 18392477 IL6 interleukin 6 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1352582 W RGD:9068941 20211008 RGD PMID:12773095|PMID:21881215|PMID:22029668|PMID:28186964|REF_RGD_ID:127229952|REF_RGD_ID:1580493|REF_RGD_ID:5686834|REF_RGD_ID:5686839 18392477 IL6 interleukin 6 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:2901 W RGD:9068941 20211008 RGD PMID:23825534|REF_RGD_ID:11062097 18392477 IL6 interleukin 6 gene PW:0000915 interleukin-23 signaling pathway ISO RGD:1352582 W RGD:9068941 20211008 PID PID:200154 18392477 IL6 interleukin 6 gene PW:0000916 interleukin-27 signaling pathway ISO RGD:1352582 W RGD:9068941 20211008 PID PID:200028 18392477 IL6 interleukin 6 gene PW:0000926 pro-inflammatory cytokine mediated pathway ISO RGD:2901 W RGD:9068941 20211008 RGD MMO:0000166, MMO:0000669, MMO:0000656 PMID:29091898|REF_RGD_ID:15090820 18392700 SLC22A8 solute carrier family 22 member 8 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:732952 W RGD:9068941 20211008 SMPDB SMP:00590 18392700 SLC22A8 solute carrier family 22 member 8 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:732952 W RGD:9068941 20211008 SMPDB SMP:00086 18392721 GNA15 G protein subunit alpha 15 gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:619751 W RGD:9068941 20211008 RGD PMID:9685675|REF_RGD_ID:728647 18392721 GNA15 G protein subunit alpha 15 gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:732130 W RGD:9068941 20211008 RGD PMID:11395409|REF_RGD_ID:5131495 18392721 GNA15 G protein subunit alpha 15 gene PW:0000506 endothelin signaling pathway ISO RGD:732130 W RGD:9068941 20211008 PID PID:200005 18392721 GNA15 G protein subunit alpha 15 gene PW:0000565 eicosanoid signaling pathway ISO RGD:732130 W RGD:9068941 20211008 PID PID:200082 18392721 GNA15 G protein subunit alpha 15 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:732130 W RGD:9068941 20211008 PID PID:200046|PID:200123|PID:200211 18392871 RANBP2 RAN binding protein 2 gene PW:0001626 CRM1 export pathway ISO RGD:1351414 W RGD:9068941 20211008 RGD PMID:23583578|REF_RGD_ID:9743967 18392871 RANBP2 RAN binding protein 2 gene PW:0002061 mitochondria transport pathway ISO RGD:1351414 W RGD:9068941 20211008 RGD PMID:25612908|REF_RGD_ID:10402141 18392921 GFER growth factor, augmenter of liver regeneration gene PW:0002139 intermembrane space assembly pathway of mitochondrial protein import ISO RGD:736290 W RGD:9068941 20211008 RGD PMID:26214018|REF_RGD_ID:10412663 18392921 GFER growth factor, augmenter of liver regeneration gene PW:0002637 mitochondrial iron-sulfur cluster export pathway ISO RGD:736290 W RGD:9068941 20211008 RGD PMID:25245479|REF_RGD_ID:11554190 18392931 DDX42 DEAD-box helicase 42 gene PW:0001073 spliceosome pathway ISO RGD:1312619 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18392971 ZFYVE9 zinc finger FYVE-type containing 9 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1321999 W RGD:9068941 20211008 PID PID:200227 18392971 ZFYVE9 zinc finger FYVE-type containing 9 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1321999 W RGD:9068941 20211008 RGD PMID:12809600|REF_RGD_ID:2298922 18393121 ORAI1 ORAI calcium release-activated calcium modulator 1 gene PW:0001139 calcium transport pathway ISO RGD:1606201 W RGD:9068941 20211008 RGD PMID:22914293|REF_RGD_ID:7204692 18393121 ORAI1 ORAI calcium release-activated calcium modulator 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1606201 W RGD:9068941 20211008 RGD PMID:22914293|REF_RGD_ID:7204692 18393567 AGRN agrin gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:10117 W RGD:9068941 20211008 RGD PMID:23032192|REF_RGD_ID:8549508 18393620 EFNA3 ephrin A3 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1352863 W RGD:9068941 20211008 PID PID:200142 18393620 EFNA3 ephrin A3 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:620390 W RGD:9068941 20211008 RGD PMID:10954848|REF_RGD_ID:634739 18393746 SYT7 synaptotagmin 7 gene PW:0000674 insulin secretion pathway ISO RGD:62013 W RGD:9068941 20211008 RGD PMID:17709608|PMID:18713958|REF_RGD_ID:2311143|REF_RGD_ID:2311148 18393746 SYT7 synaptotagmin 7 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:736086 W RGD:9068941 20211008 RGD PMID:15534041|PMID:18713958|REF_RGD_ID:2311148|REF_RGD_ID:7204679 18394113 MDM4 MDM4 regulator of p53 gene PW:0000718 p53 signaling pathway ISO RGD:1319584 W RGD:9068941 20211008 PID PID:200206 18394113 MDM4 MDM4 regulator of p53 gene PW:0000718 p53 signaling pathway ISO RGD:1319584 W RGD:9068941 20211008 RGD PMID:16601750|PMID:19450511|REF_RGD_ID:2316155|REF_RGD_ID:2316156 18394113 MDM4 MDM4 regulator of p53 gene PW:0000720 altered p53 signaling pathway ISO RGD:1319584 W RGD:9068941 20211008 RGD PMID:23262034|REF_RGD_ID:8663434 18394138 RPA3 replication protein A3 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1315635 W RGD:9068941 20211008 RGD PMID:19154342|REF_RGD_ID:7246926 18394138 RPA3 replication protein A3 gene PW:0000662 mismatch repair pathway ISO RGD:1315635 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18394174 BAG4 BAG cochaperone 4 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1350570 W RGD:9068941 20211008 PID PID:200102 18394174 BAG4 BAG cochaperone 4 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1350570 W RGD:9068941 20211008 RGD PMID:12655295|REF_RGD_ID:2292150 18394174 BAG4 BAG cochaperone 4 gene PW:0000961 ceramide signaling pathway ISO RGD:1350570 W RGD:9068941 20211008 PID PID:200119 18394431 AGRP agouti related neuropeptide gene PW:0000365 melanocortin system pathway ISO RGD:2068 W RGD:9068941 20211008 RGD PMID:10875247|REF_RGD_ID:632165 18394431 AGRP agouti related neuropeptide gene PW:0000365 melanocortin system pathway ISO RGD:736333 W RGD:9068941 20211008 RGD PMID:15189116|REF_RGD_ID:1357925 18394431 AGRP agouti related neuropeptide gene PW:0000366 altered melanocortin system pathway ISO RGD:736333 W RGD:9068941 20211008 RGD PMID:15189116|REF_RGD_ID:1357925 18394431 AGRP agouti related neuropeptide gene PW:0000540 obesity pathway ISO RGD:733559 W RGD:9068941 20211008 RGD PMID:15189116|REF_RGD_ID:1357925 18394431 AGRP agouti related neuropeptide gene PW:0000659 syndecan signaling pathway ISO RGD:736333 W RGD:9068941 20211008 PID PID:200198 18394608 PARP14 poly(ADP-ribose) polymerase family member 14 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1344897 W RGD:9068941 20211008 PID PID:200022 18394608 PARP14 poly(ADP-ribose) polymerase family member 14 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1344897 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18394811 GALE UDP-galactose-4-epimerase gene PW:0000042 galactose metabolic pathway ISO RGD:733015 W RGD:9068941 20211008 SMPDB SMP:00043 18394811 GALE UDP-galactose-4-epimerase gene PW:0000055 nucleotide sugar metabolic pathway ISO RGD:733015 W RGD:9068941 20211008 SMPDB SMP:00010 18394811 GALE UDP-galactose-4-epimerase gene PW:0002092 galactosemia pathway ISO RGD:733015 W RGD:9068941 20211008 SMPDB SMP:00182 18394811 GALE UDP-galactose-4-epimerase gene PW:0002093 GALE deficiency pathway ISO RGD:733015 W RGD:9068941 20211008 SMPDB SMP:00496 18394811 GALE UDP-galactose-4-epimerase gene PW:0002094 galactokinase deficiency pathway ISO RGD:733015 W RGD:9068941 20211008 SMPDB SMP:00495 18394853 BNIP3 BCL2 interacting protein 3 gene PW:0000104 intrinsic apoptotic pathway ISO RGD:1350913 W RGD:9068941 20211008 RGD PMID:19641503|REF_RGD_ID:2314029 18394853 BNIP3 BCL2 interacting protein 3 gene PW:0000104 intrinsic apoptotic pathway ISO RGD:620800 W RGD:9068941 20211008 RGD PMID:14972662|REF_RGD_ID:2314028 18394853 BNIP3 BCL2 interacting protein 3 gene PW:0000180 mTOR signaling pathway ISO RGD:1350913 W RGD:9068941 20211008 PID PID:200096 18394853 BNIP3 BCL2 interacting protein 3 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1350913 W RGD:9068941 20211008 PID PID:200202 18394853 BNIP3 BCL2 interacting protein 3 gene PW:0001842 mitochondrial autophagy pathway ISO RGD:1350913 W RGD:9068941 20211008 RGD PMID:23065344|PMID:25840011|REF_RGD_ID:10400888|REF_RGD_ID:10401098 18394901 HMGB1 high mobility group box 1 gene PW:0000662 mismatch repair pathway ISO RGD:1605729 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18394901 HMGB1 high mobility group box 1 gene PW:0000926 pro-inflammatory cytokine mediated pathway ISO RGD:2802 W RGD:9068941 20211008 RGD MMO:0000166, MMO:0000669, MMO:0000656 PMID:29091898|REF_RGD_ID:15090820 18394901 HMGB1 high mobility group box 1 gene PW:0001508 cisplatin drug pathway ISO RGD:1605729 W RGD:9068941 20211008 RGD PMID:20046924|REF_RGD_ID:8548475 18395032 EIF4G1 eukaryotic translation initiation factor 4 gamma 1 gene PW:0000580 translation initiation pathway ISO RGD:1314591 W RGD:9068941 20211008 RGD PMID:22815232|PMID:24499181|REF_RGD_ID:10002776|REF_RGD_ID:10044017 18395244 HACL1 2-hydroxyacyl-CoA lyase 1 gene PW:0001705 Refsum disease pathway ISO RGD:1607054 W RGD:9068941 20211008 SMPDB SMP:00451 18395244 HACL1 2-hydroxyacyl-CoA lyase 1 gene PW:0002564 phytanic acid degradation pathway ISO RGD:1607054 W RGD:9068941 20211008 SMPDB SMP:00450 18395279 MECR mitochondrial trans-2-enoyl-CoA reductase gene PW:0001136 fatty acid elongation pathway ISO RGD:733084 W RGD:9068941 20211008 SMPDB SMP:00054 18395357 SMAD9 SMAD family member 9 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1350114 W RGD:9068941 20211008 PID PID:200144 18395357 SMAD9 SMAD family member 9 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:71004 W RGD:9068941 20211008 RGD PMID:16361357|REF_RGD_ID:1580077 18395418 MIOX myo-inositol oxygenase gene PW:0000046 inositol metabolic pathway ISO RGD:737368 W RGD:9068941 20211008 SMPDB SMP:00011 18395926 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 gene PW:0001073 spliceosome pathway ISO RGD:1318867 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18395991 DYNLRB2 dynein light chain roadblock-type 2 gene PW:0002061 mitochondria transport pathway ISO RGD:1315823 W RGD:9068941 20211008 RGD PMID:21936784|REF_RGD_ID:10402142 18396012 POLR3F RNA polymerase III subunit F gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1315038 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18396077 SOCS4 suppressor of cytokine signaling 4 gene PW:0000209 Jak-Stat signaling pathway ISO RGD:1315155 W RGD:9068941 20211008 RGD PMID:14607831|REF_RGD_ID:1357941 18396338 TUBB1 tubulin beta 1 class VI gene PW:0001610 tyrosinemia type III pathway ISO RGD:1345439 W RGD:9068941 20211008 SMPDB SMP:00434 18396338 TUBB1 tubulin beta 1 class VI gene PW:0001678 vinblastine pharmacodynamics pathway ISO RGD:1345439 W RGD:9068941 20211008 SMPDB SMP:00436 18396338 TUBB1 tubulin beta 1 class VI gene PW:0001680 vincristine pharmacodynamics pathway ISO RGD:1345439 W RGD:9068941 20211008 SMPDB SMP:00437 18396338 TUBB1 tubulin beta 1 class VI gene PW:0001682 vindesine pharmacodynamics pathway ISO RGD:1345439 W RGD:9068941 20211008 SMPDB SMP:00438 18396338 TUBB1 tubulin beta 1 class VI gene PW:0001684 vinorelbine pharmacodynamics pathway ISO RGD:1345439 W RGD:9068941 20211008 SMPDB SMP:00439 18396338 TUBB1 tubulin beta 1 class VI gene PW:0001770 docetaxel pharmacodynamics pathway ISO RGD:1345439 W RGD:9068941 20211008 SMPDB SMP:00435 18396378 COL6A1 collagen type VI alpha 1 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1352880 W RGD:9068941 20211008 PID PID:200156 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0000064 propanoate metabolic pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00016 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00032 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001778 propionic acidemia pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00236 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00384 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001810 methylmalonic acidemia pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00200 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001811 methylmalonic aciduria, cobalamin-related pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00201 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001870 maple syrup urine disease pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00199 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001874 isovaleric acidemia pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00523 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00139 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00140 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0002289 malonic aciduria pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00198|SMP:00502 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00138 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18396439 MCEE methylmalonyl-CoA epimerase gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:1320595 W RGD:9068941 20211008 SMPDB SMP:00237 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0000375 phase I biotransformation pathway via cytochrome P450 ISO RGD:2459 W RGD:9068941 20220128 RGD PMID:6772643|REF_RGD_ID:151347456 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0000730 warfarin pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 RGD PMID:26655108|REF_RGD_ID:11354883 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0000838 tamoxifen pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 RGD PMID:12971802|REF_RGD_ID:5129544 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0001124 axitinib pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 RGD PMID:22170007|REF_RGD_ID:6907361 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0001466 clopidogrel pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00610 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0001467 clopidogrel pharmacodynamics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00260 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00640 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0001986 imipramine pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00625 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00422 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0002311 doxepin pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00641 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0002318 caffeine pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00028 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00327 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0002386 clomipramine pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00639 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0002537 lidocaine pharmacokinetics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00620 18396591 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:735711 W RGD:9068941 20211008 SMPDB SMP:00328|SMP:00398 18396772 IL2RG interleukin 2 receptor subunit gamma gene PW:0000907 interleukin-2 signaling pathway ISO RGD:731533 W RGD:9068941 20211008 PID PID:200098 18396772 IL2RG interleukin 2 receptor subunit gamma gene PW:0000912 interleukin-4 signaling pathway ISO RGD:731533 W RGD:9068941 20211008 PID PID:200022 18396772 IL2RG interleukin 2 receptor subunit gamma gene PW:0000914 interleukin-12 signaling pathway ISO RGD:731533 W RGD:9068941 20211008 PID PID:200045 18396889 OS9 OS9 endoplasmic reticulum lectin gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1605693 W RGD:9068941 20211008 RGD PMID:19364912|REF_RGD_ID:6483358 18396918 PPIB peptidylprolyl isomerase B gene PW:0000141 retinol metabolic pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00074 18396918 PPIB peptidylprolyl isomerase B gene PW:0000659 syndecan signaling pathway ISO RGD:732990 W RGD:9068941 20211008 PID PID:200156 18396918 PPIB peptidylprolyl isomerase B gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00648 18396918 PPIB peptidylprolyl isomerase B gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00600 18396918 PPIB peptidylprolyl isomerase B gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00433 18396918 PPIB peptidylprolyl isomerase B gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00622 18396918 PPIB peptidylprolyl isomerase B gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00406 18396918 PPIB peptidylprolyl isomerase B gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00590 18396918 PPIB peptidylprolyl isomerase B gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00086 18396918 PPIB peptidylprolyl isomerase B gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00640 18396918 PPIB peptidylprolyl isomerase B gene PW:0001585 vitamin A deficiency pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00336 18396918 PPIB peptidylprolyl isomerase B gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00327 18396918 PPIB peptidylprolyl isomerase B gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00601 18396918 PPIB peptidylprolyl isomerase B gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:732990 W RGD:9068941 20211008 SMPDB SMP:00442 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00072 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0000049 cysteine metabolic pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00013 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0000134 glutathione metabolic pathway ISO RGD:619871 W RGD:9068941 20211008 RGD PMID:16137247|PMID:16183645|REF_RGD_ID:1582661|REF_RGD_ID:1582663 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0000134 glutathione metabolic pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00015 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0001979 homocarnosinosis pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00385 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0002019 glutathione synthase deficiency pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00143|SMP:00337 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00136 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0002218 ocular nonnephropathic cystinosis pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00722 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0002562 glutathionuria disease pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00501 18397195 GCLM glutamate-cysteine ligase modifier subunit gene PW:0002568 mercaptolactate-cysteine disulfiduria pathway ISO RGD:731551 W RGD:9068941 20211008 SMPDB SMP:00499 18397303 XRCC2 X-ray repair cross complementing 2 gene PW:0000202 homologous recombination pathway of double-strand break repair ISO RGD:1349181 W RGD:9068941 20211008 RGD PMID:20690856|REF_RGD_ID:8662366 18397369 GGCX gamma-glutamyl carboxylase gene PW:0000731 warfarin pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00268 18397369 GGCX gamma-glutamyl carboxylase gene PW:0001016 vitamin K metabolic pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00464 18397369 GGCX gamma-glutamyl carboxylase gene PW:0001600 acenocoumarol pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00269 18397369 GGCX gamma-glutamyl carboxylase gene PW:0001637 alteplase pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00280 18397369 GGCX gamma-glutamyl carboxylase gene PW:0001655 aminocaproic acid pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00286 18397369 GGCX gamma-glutamyl carboxylase gene PW:0001664 anistreplase pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00281 18397369 GGCX gamma-glutamyl carboxylase gene PW:0001788 tranexamic acid pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00287 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002149 bivalirudin pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00277 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002223 aprotinin pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00288 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002229 argatroban pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00276 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002258 reteplase pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00285 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002329 heparin pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00274 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002332 enoxaparin pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00272 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002437 fondaparinux pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00273 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002494 phenindione pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00655 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002497 dicoumarol pharmacodynamics pathway ISO RGD:68554 W RGD:9068941 20211008 SMPDB SMP:00270|SMP:00656 18397369 GGCX gamma-glutamyl carboxylase gene PW:0002592 vitamin K cycle pathway ISO RGD:68554 W RGD:9068941 20211008 RGD PMID:26663892|REF_RGD_ID:11344916 18397431 MDC1 mediator of DNA damage checkpoint 1 gene PW:0001338 histone modification pathway ISO RGD:1348817 W RGD:9068941 20211008 RGD PMID:23642229|REF_RGD_ID:9479074 18397431 MDC1 mediator of DNA damage checkpoint 1 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1348817 W RGD:9068941 20211008 RGD PMID:21533982|PMID:24002223|REF_RGD_ID:8661232|REF_RGD_ID:8661242 18397479 RANBP3 RAN binding protein 3 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1313698 W RGD:9068941 20211008 PID PID:200077 18397519 PROZ protein Z, vitamin K dependent plasma glycoprotein gene PW:0000474 coagulation cascade pathway ISO RGD:1318570 W RGD:9068941 20211008 RGD PMID:23690629|REF_RGD_ID:11352284 18397681 IRF4 interferon regulatory factor 4 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1317594 W RGD:9068941 20211008 PID PID:200022 18398058 FZD8 frizzled class receptor 8 gene PW:0000008 Wnt signaling pathway ISO RGD:1558526 W RGD:9068941 20211008 RGD 18398123 CNGA4 cyclic nucleotide gated channel subunit alpha 4 gene PW:0001139 calcium transport pathway ISO RGD:1603715 W RGD:9068941 20211008 RGD PMID:12087135|REF_RGD_ID:6893549 18398123 CNGA4 cyclic nucleotide gated channel subunit alpha 4 gene PW:0001139 calcium transport pathway ISO RGD:619844 W RGD:9068941 20211008 RGD PMID:12087135|REF_RGD_ID:6893549 18398123 CNGA4 cyclic nucleotide gated channel subunit alpha 4 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1603715 W RGD:9068941 20211008 RGD PMID:22435804|REF_RGD_ID:7204690 18398227 SCRIB scribble planar cell polarity protein gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1321472 W RGD:9068941 20211008 RGD PMID:17226800|REF_RGD_ID:2293492 18398308 ATF2 activating transcription factor 2 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:732287 W RGD:9068941 20211008 PID PID:200045 18398308 ATF2 activating transcription factor 2 gene PW:0000998 adenosine signaling pathway ISO RGD:732287 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0000769 omeprazole pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00226 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001836 roxatidine acetate pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00734 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001845 ranitidine pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00230 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001848 rabeprazole pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00229 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001884 pirenzepine pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00246 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001890 pantoprazole pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00228 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001906 nizatidine pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00233 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0001965 lansoprazole pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00227 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0002039 famotidine pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00231 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0002112 cimetidine pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00232 18398454 SLC26A3 solute carrier family 26 member 3 gene PW:0002184 esomeprazole pharmacodynamics pathway ISO RGD:1346275 W RGD:9068941 20211008 SMPDB SMP:00225 18399066 TAOK2 TAO kinase 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1351729 W RGD:9068941 20211008 PID PID:200018 18399066 TAOK2 TAO kinase 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1351729 W RGD:9068941 20211008 RGD PMID:20626350|REF_RGD_ID:7240533 18399117 ULK2 unc-51 like autophagy activating kinase 2 gene PW:0000180 mTOR signaling pathway ISO RGD:1320930 W RGD:9068941 20211008 PID PID:200096 18399117 ULK2 unc-51 like autophagy activating kinase 2 gene PW:0000278 autophagy pathway ISO RGD:1320930 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18399262 PDE6C phosphodiesterase 6C gene PW:0000962 visual phototransduction pathway ISO RGD:1320406 W RGD:9068941 20211008 RGD PMID:15224133|REF_RGD_ID:6893540 18399514 SIGIRR single Ig and TIR domain containing gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1604804 W RGD:9068941 20211008 RGD PMID:20081871|REF_RGD_ID:5490209 18399557 CLTA clathrin light chain A gene PW:0000387 Arf family mediated signaling pathway ISO RGD:733774 W RGD:9068941 20211008 PID PID:200195 18399557 CLTA clathrin light chain A gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:733774 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18399896 NADK2 NAD kinase 2, mitochondrial gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:1604237 W RGD:9068941 20211008 RGD PMID:25641397|REF_RGD_ID:11250407 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00296 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001139 calcium transport pathway ISO RGD:731733 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:731733 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00379 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00665 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00376 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00375 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00659 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00660 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00323 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00307 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00324 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00380 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00381 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00382 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00366 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00302 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00378 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00332 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00331 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00301 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00325 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00359 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002134 bupranolol drug pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00670 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00670 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00300 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00299 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00296 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00298 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00305 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00303 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00306 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00326 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00666 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00327 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00329 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00662 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00663 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00328 18400007 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:731733 W RGD:9068941 20211008 SMPDB SMP:00367 18400205 CLIP1 CAP-Gly domain containing linker protein 1 gene PW:0000180 mTOR signaling pathway ISO RGD:69221 W RGD:9068941 20211008 PID PID:200096 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00133 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00132 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00134 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001880 iminoglycinuria pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00193 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00105 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0001977 Hartnup disease pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00189 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00100 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00115 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00097 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00122 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00088 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00078 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00090 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002214 cystinuria pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00723 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00118 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00135 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00121 18400575 SLC38A4 solute carrier family 38 member 4 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:1347009 W RGD:9068941 20211008 SMPDB SMP:00108 18400737 ADAM19 ADAM metallopeptidase domain 19 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:735923 W RGD:9068941 20211008 RGD PMID:15688065|REF_RGD_ID:2317976 18400737 ADAM19 ADAM metallopeptidase domain 19 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:735924 W RGD:9068941 20211008 RGD PMID:15688065|REF_RGD_ID:2317976 18400793 HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 gene PW:0001073 spliceosome pathway ISO RGD:1347066 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18400840 MTA3 metastasis associated 1 family member 3 gene PW:0001409 CHD family mediated chromatin remodeling pathway ISO RGD:1315624 W RGD:9068941 20211008 RGD PMID:24880148|REF_RGD_ID:9585661 18400998 RPLP1 ribosomal protein lateral stalk subunit P1 gene PW:0000101 translation pathway ISO RGD:736952 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18400998 RPLP1 ribosomal protein lateral stalk subunit P1 gene PW:0001066 ribosome biogenesis pathway ISO RGD:736952 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18401026 GDAP1 ganglioside induced differentiation associated protein 1 gene PW:0001998 mitochondria fission pathway ISO RGD:1319106 W RGD:9068941 20211008 RGD PMID:21683788|PMID:24442478|REF_RGD_ID:10402101|REF_RGD_ID:10402102 18401050 PTPN13 protein tyrosine phosphatase non-receptor type 13 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1349944 W RGD:9068941 20211008 PID PID:200204 18401133 HHAT hedgehog acyltransferase gene PW:0000122 Hedgehog signaling pathway ISO RGD:1351064 W RGD:9068941 20211008 PID PID:200168 18401133 HHAT hedgehog acyltransferase gene PW:0000122 Hedgehog signaling pathway ISO RGD:1351064 W RGD:9068941 20211008 RGD PMID:20716670|REF_RGD_ID:5510013 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00064 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000045 pentose phosphate pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00031 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:735815 W RGD:9068941 20211008 PID PID:200202 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000640 glycolysis pathway ISO RGD:735815 W RGD:9068941 20211008 RGD PMID:5251864|REF_RGD_ID:2302796 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000640 glycolysis pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00040 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000641 gluconeogenesis pathway ISO RGD:735815 W RGD:9068941 20211008 RGD PMID:5251864|REF_RGD_ID:2302796 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0000641 gluconeogenesis pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00128 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00563 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0001629 transaldolase deficiency pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00520 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0001704 ribose 5-phosphate isomerase deficiency pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00519 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00573 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00531 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00562 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00725 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0002360 Fanconi syndrome pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00572 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0002388 fructosuria pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00561 18401308 LOC103230584 uncharacterized LOC103230584 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:735815 W RGD:9068941 20211008 SMPDB SMP:00560 18401389 UTP23 UTP23 small subunit processome component gene PW:0001066 ribosome biogenesis pathway ISO RGD:1601941 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18401451 THBS1 thrombospondin 1 gene PW:0000659 syndecan signaling pathway ISO RGD:1345942 W RGD:9068941 20211008 PID PID:200134 18401482 AMDHD2 amidohydrolase domain containing 2 gene PW:0000152 amino sugar metabolic pathway ISO RGD:1603049 W RGD:9068941 20211008 SMPDB SMP:00045 18401482 AMDHD2 amidohydrolase domain containing 2 gene PW:0001631 Tay-Sachs disease pathway ISO RGD:1603049 W RGD:9068941 20211008 SMPDB SMP:00390 18401482 AMDHD2 amidohydrolase domain containing 2 gene PW:0001702 french type sialuria pathway ISO RGD:1603049 W RGD:9068941 20211008 SMPDB SMP:00216|SMP:00217 18401482 AMDHD2 amidohydrolase domain containing 2 gene PW:0002381 sialic acid storage disease pathway ISO RGD:1603049 W RGD:9068941 20211008 SMPDB SMP:00240 18401613 DR1 down-regulator of transcription 1 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1313088 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18401720 PARVA parvin alpha gene PW:0000286 integrin mediated signaling pathway ISO RGD:1352322 W RGD:9068941 20211008 RGD PMID:16493410|REF_RGD_ID:2300344 18401873 FIG4 FIG4 phosphoinositide 5-phosphatase gene PW:0000046 inositol metabolic pathway ISO RGD:1322801 W RGD:9068941 20211008 SMPDB SMP:00011 18401873 FIG4 FIG4 phosphoinositide 5-phosphatase gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:1322801 W RGD:9068941 20211008 SMPDB SMP:00463 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:1350540 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:1350540 W RGD:9068941 20211008 SMPDB SMP:00130 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0000774 cortisol biosynthetic pathway ISO RGD:1350540 W RGD:9068941 20211008 RGD PMID:17926129|REF_RGD_ID:4892309 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0000778 testosterone biosynthetic pathway ISO RGD:1350540 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0000781 estradiol biosynthetic pathway ISO RGD:1350540 W RGD:9068941 20211008 RGD PMID:17926129|REF_RGD_ID:4892309 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0001479 lipoid congenital adrenal hyperplasia pathway ISO RGD:1350540 W RGD:9068941 20211008 SMPDB SMP:00371 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0002166 17-alpha-hydroxylase deficiency pathway ISO RGD:1350540 W RGD:9068941 20211008 SMPDB SMP:00372 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0002167 21-alpha-hydroxylase deficiency pathway ISO RGD:1350540 W RGD:9068941 20211008 SMPDB SMP:00373 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0002168 11-beta-hydroxylase deficiency pathway ISO RGD:1350540 W RGD:9068941 20211008 SMPDB SMP:00575 18401941 CYP17A1 cytochrome P450 family 17 subfamily A member 1 gene PW:0002466 apparent mineralocorticoid excess syndrome pathway ISO RGD:1350540 W RGD:9068941 20211008 SMPDB SMP:00717 18402084 ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1316156 W RGD:9068941 20211008 RGD PMID:22572993|REF_RGD_ID:7246920 18402084 ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1316156 W RGD:9068941 20211008 RGD PMID:21592869|REF_RGD_ID:9681726 18402084 ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit gene PW:0001359 altered nucleotide excision repair pathway ISO RGD:1316156 W RGD:9068941 20211008 RGD PMID:22824526|REF_RGD_ID:7246919 18402290 RAG2 recombination activating 2 gene PW:0001338 histone modification pathway ISO RGD:1313706 W RGD:9068941 20211008 RGD PMID:23642229|REF_RGD_ID:9479074 18402304 APC APC regulator of WNT signaling pathway gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:736624 W RGD:9068941 20211008 PID PID:200077 18402304 APC APC regulator of WNT signaling pathway gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:736624 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18402304 APC APC regulator of WNT signaling pathway gene PW:0000599 altered Wnt signaling, canonical pathway ISO RGD:736624 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18402304 APC APC regulator of WNT signaling pathway gene PW:0000611 endometrial cancer pathway ISO RGD:736624 W RGD:9068941 20211008 RGD PMID:12439748|REF_RGD_ID:13432145 18402304 APC APC regulator of WNT signaling pathway gene PW:0000612 colorectal cancer pathway ISO RGD:736624 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18402360 PPP2R1B protein phosphatase 2 scaffold subunit Abeta gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:1312396 W RGD:9068941 20211008 RGD PMID:23454242|REF_RGD_ID:11535052 18402490 FLAD1 flavin adenine dinucleotide synthetase 1 gene PW:0000137 riboflavin metabolic pathway ISO RGD:1604288 W RGD:9068941 20211008 SMPDB SMP:00070 18402759 LTB4R leukotriene B4 receptor gene PW:0000125 G protein mediated signaling pathway ISO RGD:1550123 W RGD:9068941 20211008 RGD PMID:16043658|REF_RGD_ID:1581956 18402919 SYBU syntabulin gene PW:0002061 mitochondria transport pathway ISO RGD:1604347 W RGD:9068941 20211008 RGD PMID:25612908|REF_RGD_ID:10402141 18403185 RAB2A RAB2A, member RAS oncogene family gene PW:0000159 Rab family mediated signaling pathway ISO RGD:68446 W RGD:9068941 20211008 RGD PMID:17629673|PMID:18171431|PMID:18570632|REF_RGD_ID:2302395|REF_RGD_ID:2302397|REF_RGD_ID:2306494 18403185 RAB2A RAB2A, member RAS oncogene family gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:68446 W RGD:9068941 20211008 RGD PMID:17629673|PMID:17717074|PMID:18570632|REF_RGD_ID:2302393|REF_RGD_ID:2302395|REF_RGD_ID:2302397 18403230 PTHLH parathyroid hormone like hormone gene PW:0000122 Hedgehog signaling pathway ISO RGD:736996 W RGD:9068941 20211008 PID PID:200168 18403312 POLR2K RNA polymerase II, I and III subunit K gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1352672 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18403312 POLR2K RNA polymerase II, I and III subunit K gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1352672 W RGD:9068941 20211008 RGD PMID:22960599|REF_RGD_ID:9588243 18403312 POLR2K RNA polymerase II, I and III subunit K gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1352672 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18403336 ASPA aspartoacylase gene PW:0001417 Canavan disease pathway ISO RGD:1350952 W RGD:9068941 20211008 SMPDB SMP:00175 18403392 NFKBIA NFKB inhibitor alpha gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:735440 W RGD:9068941 20211008 PID PID:200021|PID:200031 18403392 NFKBIA NFKB inhibitor alpha gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:735440 W RGD:9068941 20211008 RGD PMID:18267068|REF_RGD_ID:2292172 18403392 NFKBIA NFKB inhibitor alpha gene PW:0000915 interleukin-23 signaling pathway ISO RGD:735440 W RGD:9068941 20211008 PID PID:200154 18403392 NFKBIA NFKB inhibitor alpha gene PW:0000961 ceramide signaling pathway ISO RGD:735440 W RGD:9068941 20211008 PID PID:200119 18403392 NFKBIA NFKB inhibitor alpha gene PW:0000998 adenosine signaling pathway ISO RGD:735440 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18403461 RUBCN rubicon autophagy regulator gene PW:0000278 autophagy pathway ISO RGD:1353596 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18403706 PYGM glycogen phosphorylase, muscle associated gene PW:0000534 glycogen degradation pathway ISO RGD:3461 W RGD:9068941 20211008 RGD PMID:11692172|REF_RGD_ID:1599897 18403706 PYGM glycogen phosphorylase, muscle associated gene PW:0000534 glycogen degradation pathway ISO RGD:737329 W RGD:9068941 20211008 RGD PMID:11340058|PMID:1544539|REF_RGD_ID:1642822|REF_RGD_ID:2304109 18403815 HIF3A hypoxia inducible factor 3 subunit alpha gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1605351 W RGD:9068941 20211008 RGD PMID:22169972|REF_RGD_ID:6483352 18403815 HIF3A hypoxia inducible factor 3 subunit alpha gene PW:0000360 hypoxia inducible factor pathway ISO RGD:70332 W RGD:9068941 20211008 RGD PMID:11237857|REF_RGD_ID:68201 18403865 LTV1 LTV1 ribosome biogenesis factor gene PW:0001066 ribosome biogenesis pathway ISO RGD:1322627 W RGD:9068941 20211008 RGD PMID:20137954|PMID:24424021|REF_RGD_ID:10002748|REF_RGD_ID:10002751 18403984 ACSM3 acyl-CoA synthetase medium chain family member 3 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:735798 W RGD:9068941 20211008 RGD PMID:17762044|REF_RGD_ID:2317576 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0000042 galactose metabolic pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00043 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0000055 nucleotide sugar metabolic pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00010 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0002072 lactose biosynthetic pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00444 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0002092 galactosemia pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00182 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0002093 GALE deficiency pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00496 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0002094 galactokinase deficiency pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00495 18404048 GALT galactose-1-phosphate uridylyltransferase gene PW:0002467 Glut1 deficiency syndrome pathway ISO RGD:1315126 W RGD:9068941 20211008 SMPDB SMP:00580 18404119 CD36 CD36 molecule (CD36 blood group) gene PW:0000141 retinol metabolic pathway ISO RGD:619554 W RGD:9068941 20211008 RGD PMID:21718801|REF_RGD_ID:6484679 18404165 IGF1R insulin like growth factor 1 receptor gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:2869 W RGD:9068941 20211008 RGD PMID:15272025|PMID:20042609|REF_RGD_ID:1581313|REF_RGD_ID:7242068 18404165 IGF1R insulin like growth factor 1 receptor gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:68997 W RGD:9068941 20211008 PID PID:200100 18404165 IGF1R insulin like growth factor 1 receptor gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:68997 W RGD:9068941 20211008 RGD PMID:15862547|REF_RGD_ID:1626333 18404165 IGF1R insulin like growth factor 1 receptor gene PW:0000992 E-cadherin signaling pathway ISO RGD:68997 W RGD:9068941 20211008 PID PID:200182 18404199 CHIT1 chitinase 1 gene PW:0000152 amino sugar metabolic pathway ISO RGD:1313797 W RGD:9068941 20211008 SMPDB SMP:00045 18404199 CHIT1 chitinase 1 gene PW:0001631 Tay-Sachs disease pathway ISO RGD:1313797 W RGD:9068941 20211008 SMPDB SMP:00390 18404199 CHIT1 chitinase 1 gene PW:0001702 french type sialuria pathway ISO RGD:1313797 W RGD:9068941 20211008 SMPDB SMP:00216|SMP:00217 18404199 CHIT1 chitinase 1 gene PW:0002381 sialic acid storage disease pathway ISO RGD:1313797 W RGD:9068941 20211008 SMPDB SMP:00240 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00133 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00132 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00134 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001880 iminoglycinuria pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00193 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00105 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0001977 Hartnup disease pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00189 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00100 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00115 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00097 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00122 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00088 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00078 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00090 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002214 cystinuria pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00723 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00118 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00135 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00121 18404225 SLC7A8 solute carrier family 7 member 8 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:1345085 W RGD:9068941 20211008 SMPDB SMP:00108 18404316 BMP6 bone morphogenetic protein 6 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1353193 W RGD:9068941 20211008 PID PID:200144 18404360 PCYT1A phosphate cytidylyltransferase 1A, choline gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:737380 W RGD:9068941 20211008 SMPDB SMP:00025 18404360 PCYT1A phosphate cytidylyltransferase 1A, choline gene PW:0001431 lamivudine pharmacokinetics pathway ISO RGD:737380 W RGD:9068941 20211008 SMPDB SMP:00649 18404756 HNRNPC heterogeneous nuclear ribonucleoprotein C gene PW:0001073 spliceosome pathway ISO RGD:1320619 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18404915 FDXR ferredoxin reductase gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:734233 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18404915 FDXR ferredoxin reductase gene PW:0000773 aldosterone biosynthetic pathway ISO RGD:734233 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18404915 FDXR ferredoxin reductase gene PW:0000774 cortisol biosynthetic pathway ISO RGD:734233 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18404915 FDXR ferredoxin reductase gene PW:0000778 testosterone biosynthetic pathway ISO RGD:734233 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18404915 FDXR ferredoxin reductase gene PW:0000781 estradiol biosynthetic pathway ISO RGD:734233 W RGD:9068941 20211008 RGD PMID:18821018|REF_RGD_ID:2325883 18404915 FDXR ferredoxin reductase gene PW:0002635 mitochondrial iron-sulfur cluster protein biogenesis pathway ISO RGD:734233 W RGD:9068941 20211008 RGD PMID:25245479|REF_RGD_ID:11554190 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:11933257|REF_RGD_ID:1535021 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00033 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000140 folate metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:11933257|REF_RGD_ID:1535021 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000140 folate metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00053 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:11933257|PMID:22332074|REF_RGD_ID:1535021|REF_RGD_ID:7242561 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000398 homocysteine metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:20814827|REF_RGD_ID:7242426 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000399 remethylation pathway of homocysteine metabolism - cobalamin dependent ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:20814827|REF_RGD_ID:7242426 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0000932 methotrexate pharmacodynamics pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00432 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0001207 folate cycle metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0001208 altered folate cycle metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0001209 altered folate mediated one-carbon metabolic pathway ISO RGD:733483 W RGD:9068941 20211008 RGD PMID:22353665|REF_RGD_ID:7242562 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0001841 homocystinuria pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00177 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0001868 hypermethioninemia pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00221 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0002236 hereditary folate malabsorption pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00724 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00222 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00340 18404977 MTHFR methylenetetrahydrofolate reductase gene PW:0002471 hypermethioninemia pathway ISO RGD:733483 W RGD:9068941 20211008 SMPDB SMP:00341 18405067 GP5 glycoprotein V platelet gene PW:0000508 platelet aggregation pathway ISO RGD:736629 W RGD:9068941 20211008 RGD PMID:11487006|REF_RGD_ID:1580446 18405147 ERBB3 erb-b2 receptor tyrosine kinase 3 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:69323 W RGD:9068941 20211008 RGD PMID:14711829|REF_RGD_ID:2289958 18405147 ERBB3 erb-b2 receptor tyrosine kinase 3 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:69323 W RGD:9068941 20211008 RGD Neuregulin stimulation of glucose transport in muscle cells PMID:15007074|REF_RGD_ID:1642700 18405147 ERBB3 erb-b2 receptor tyrosine kinase 3 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:733426 W RGD:9068941 20211008 PID PID:200159 18405147 ERBB3 erb-b2 receptor tyrosine kinase 3 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:733426 W RGD:9068941 20211008 RGD PMID:16829981|PMID:18519747|REF_RGD_ID:2317965|REF_RGD_ID:2317988 18405147 ERBB3 erb-b2 receptor tyrosine kinase 3 gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:733426 W RGD:9068941 20211008 RGD PMID:20889352|REF_RGD_ID:5133679 18405355 SLC18A3 solute carrier family 18 member A3 gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:732691 W RGD:9068941 20211008 RGD PMID:23677775|REF_RGD_ID:8549504 18405355 SLC18A3 solute carrier family 18 member A3 gene PW:0000843 acetylcholine signaling pathway via muscarinic acetylcholine receptor ISO RGD:732691 W RGD:9068941 20211008 RGD PMID:23677775|REF_RGD_ID:8549504 18405487 SRR serine racemase gene PW:0001670 sarcosinemia pathway ISO RGD:1352406 W RGD:9068941 20211008 SMPDB SMP:00244 18405487 SRR serine racemase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1352406 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18405487 SRR serine racemase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1352406 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18405487 SRR serine racemase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1352406 W RGD:9068941 20211008 SMPDB SMP:00179 18405512 LDLR low density lipoprotein receptor gene PW:0000518 atherosclerosis pathway ISO RGD:735594 W RGD:9068941 20211008 RGD PMID:12969990|REF_RGD_ID:1581826 18405554 WNT3 Wnt family member 3 gene PW:0000008 Wnt signaling pathway ISO RGD:1344120 W RGD:9068941 20211008 RGD 18405554 WNT3 Wnt family member 3 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1344120 W RGD:9068941 20211008 RGD PMID:18765832|REF_RGD_ID:2313743 18405567 CNOT6 CCR4-NOT transcription complex subunit 6 gene PW:0000808 microRNA pathway ISO RGD:1347023 W RGD:9068941 20211008 RGD PMID:23337855|REF_RGD_ID:9850101 18405603 PPP3CC protein phosphatase 3 catalytic subunit gamma gene PW:0000315 calcineurin signaling pathway ISO RGD:1347828 W RGD:9068941 20211008 RGD PMID:15336966|REF_RGD_ID:1579951 18405603 PPP3CC protein phosphatase 3 catalytic subunit gamma gene PW:0000394 dopamine signaling pathway ISO RGD:1347828 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18405791 ATG3 autophagy related 3 gene PW:0000278 autophagy pathway ISO RGD:1353416 W RGD:9068941 20211008 RGD PMID:15325588|PMID:20034776|REF_RGD_ID:1643329|REF_RGD_ID:4889529 18405791 ATG3 autophagy related 3 gene PW:0000278 autophagy pathway ISO RGD:708464 W RGD:9068941 20211008 RGD PMID:17110912|REF_RGD_ID:1643237 18405852 WASHC4 WASH complex subunit 4 gene PW:0002430 retromer-mediated pathway ISO RGD:1603694 W RGD:9068941 20211008 RGD PMID:25619244|REF_RGD_ID:10450542 18405969 IL1B interleukin 1 beta gene PW:0000883 interleukin-1 signaling pathway ISO RGD:730981 W RGD:9068941 20211008 PID PID:200089 18405969 IL1B interleukin 1 beta gene PW:0000883 interleukin-1 signaling pathway ISO RGD:730981 W RGD:9068941 20211008 RGD PMID:20081871|REF_RGD_ID:5490209 18405969 IL1B interleukin 1 beta gene PW:0000896 type II interferon signaling pathway ISO RGD:730981 W RGD:9068941 20211008 PID PID:200129 18405969 IL1B interleukin 1 beta gene PW:0000914 interleukin-12 signaling pathway ISO RGD:730981 W RGD:9068941 20211008 PID PID:200045 18405969 IL1B interleukin 1 beta gene PW:0000915 interleukin-23 signaling pathway ISO RGD:730981 W RGD:9068941 20211008 PID PID:200154 18405969 IL1B interleukin 1 beta gene PW:0000916 interleukin-27 signaling pathway ISO RGD:730981 W RGD:9068941 20211008 PID PID:200028 18405969 IL1B interleukin 1 beta gene PW:0000926 pro-inflammatory cytokine mediated pathway ISO RGD:2891 W RGD:9068941 20211008 RGD MMO:0000166, MMO:0000669, MMO:0000656 PMID:29091898|REF_RGD_ID:15090820 18405984 ADSL adenylosuccinate lyase gene PW:0000031 purine metabolic pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00050 18405984 ADSL adenylosuccinate lyase gene PW:0000867 de novo purine biosynthetic pathway ISO RGD:1316916 W RGD:9068941 20211008 RGD PMID:20005278|REF_RGD_ID:5135488 18405984 ADSL adenylosuccinate lyase gene PW:0001417 Canavan disease pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00175 18405984 ADSL adenylosuccinate lyase gene PW:0001590 xanthinuria pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00220 18405984 ADSL adenylosuccinate lyase gene PW:0001591 xanthinuria type I pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00512 18405984 ADSL adenylosuccinate lyase gene PW:0001592 xanthinuria type II pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00513 18405984 ADSL adenylosuccinate lyase gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00210 18405984 ADSL adenylosuccinate lyase gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00537 18405984 ADSL adenylosuccinate lyase gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00203 18405984 ADSL adenylosuccinate lyase gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00364 18405984 ADSL adenylosuccinate lyase gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00365 18405984 ADSL adenylosuccinate lyase gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00428 18405984 ADSL adenylosuccinate lyase gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00427 18405984 ADSL adenylosuccinate lyase gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00167 18405984 ADSL adenylosuccinate lyase gene PW:0002294 AICA-ribosuria pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00168 18405984 ADSL adenylosuccinate lyase gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00430 18405984 ADSL adenylosuccinate lyase gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:1316916 W RGD:9068941 20211008 SMPDB SMP:00535 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00296 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00671 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00379 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001300 trehalose degradation pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00467 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001364 lactose degradation pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00457 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00431 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00413 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00133 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00665 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00376 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00375 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00659 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00132 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00134 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00660 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00323 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00307 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00402 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00324 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001880 iminoglycinuria pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00193 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00686 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00380 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00381 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00382 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00366 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00687 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00691 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00105 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00302 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00408 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00399 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00378 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001977 Hartnup disease pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00189 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00422 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00332 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00100 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00115 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00426 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00331 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00415 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00097 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00301 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00425 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00325 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00359 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00423 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00424 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00122 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002134 bupranolol drug pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00670 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00670 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00088 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00300 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00299 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00296 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00078 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00684 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00393 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00090 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002214 cystinuria pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00723 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00298 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00305 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00401 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00404 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00118 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00303 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00306 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00135 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00688 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00326 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00666 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00121 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00327 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00329 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00416 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00108 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00662 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00397 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00409 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00410 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00411 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00412 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00394 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00663 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00681 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00395 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00328|SMP:00398 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00400 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00677 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00673 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00407 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00675 18405998 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:733031 W RGD:9068941 20211008 SMPDB SMP:00367 18406056 EXOC4 exocyst complex component 4 gene PW:0000143 insulin signaling pathway ISO RGD:1353036 W RGD:9068941 20211008 PID PID:200014 18406056 EXOC4 exocyst complex component 4 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1353036 W RGD:9068941 20211008 PID PID:200182 18406087 FLCN folliculin gene PW:0000180 mTOR signaling pathway ISO RGD:1604509 W RGD:9068941 20211008 RGD PMID:27076075|REF_RGD_ID:11535042 18406122 G6PD glucose-6-phosphate dehydrogenase gene PW:0000045 pentose phosphate pathway ISO RGD:2645 W RGD:9068941 20211008 RGD PMID:2843500|REF_RGD_ID:1599574 18406122 G6PD glucose-6-phosphate dehydrogenase gene PW:0000045 pentose phosphate pathway ISO RGD:736474 W RGD:9068941 20211008 SMPDB SMP:00031 18406122 G6PD glucose-6-phosphate dehydrogenase gene PW:0000573 pentose phosphate pathway - oxidative phase ISO RGD:736474 W RGD:9068941 20211008 RGD PMID:15466941|REF_RGD_ID:1625539 18406122 G6PD glucose-6-phosphate dehydrogenase gene PW:0001629 transaldolase deficiency pathway ISO RGD:736474 W RGD:9068941 20211008 SMPDB SMP:00520 18406122 G6PD glucose-6-phosphate dehydrogenase gene PW:0001704 ribose 5-phosphate isomerase deficiency pathway ISO RGD:736474 W RGD:9068941 20211008 SMPDB SMP:00519 18406197 RPL11 ribosomal protein L11 gene PW:0000101 translation pathway ISO RGD:1318594 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18406197 RPL11 ribosomal protein L11 gene PW:0000718 p53 signaling pathway ISO RGD:1318594 W RGD:9068941 20211008 PID PID:200206 18406197 RPL11 ribosomal protein L11 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1318594 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18406277 HK1 hexokinase 1 gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00064 18406277 HK1 hexokinase 1 gene PW:0000042 galactose metabolic pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00043 18406277 HK1 hexokinase 1 gene PW:0000152 amino sugar metabolic pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00045 18406277 HK1 hexokinase 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:737450 W RGD:9068941 20211008 PID PID:200202 18406277 HK1 hexokinase 1 gene PW:0000640 glycolysis pathway ISO RGD:2796 W RGD:9068941 20230114 RGD PMID:4353083|PMID:9540816|REF_RGD_ID:2302784|REF_RGD_ID:2302851 18406277 HK1 hexokinase 1 gene PW:0001631 Tay-Sachs disease pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00390 18406277 HK1 hexokinase 1 gene PW:0001702 french type sialuria pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00216|SMP:00217 18406277 HK1 hexokinase 1 gene PW:0002092 galactosemia pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00182 18406277 HK1 hexokinase 1 gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00725 18406277 HK1 hexokinase 1 gene PW:0002381 sialic acid storage disease pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00240 18406277 HK1 hexokinase 1 gene PW:0002388 fructosuria pathway ISO RGD:737450 W RGD:9068941 20211008 SMPDB SMP:00561 18406317 PDGFRA platelet derived growth factor receptor alpha gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:730916 W RGD:9068941 20211008 PID PID:200162|PID:200201 18406457 TYMP thymidine phosphorylase gene PW:0000032 pyrimidine metabolic pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00046 18406457 TYMP thymidine phosphorylase gene PW:0001603 beta-ureidopropionase deficiency pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00172 18406457 TYMP thymidine phosphorylase gene PW:0001605 orotic aciduria 1 pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00219 18406457 TYMP thymidine phosphorylase gene PW:0002132 capecitabine pharmacokinetics pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00607 18406457 TYMP thymidine phosphorylase gene PW:0002133 capecitabine pharmacodynamics pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00469 18406457 TYMP thymidine phosphorylase gene PW:0002211 dihydropyrimidinase deficiency pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00178 18406457 TYMP thymidine phosphorylase gene PW:0002365 mitochondrial neurogastrointestinal encephalopathy syndrome pathway ISO RGD:1313979 W RGD:9068941 20211008 SMPDB SMP:00202 18406889 RUNX2 RUNX family transcription factor 2 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1348975 W RGD:9068941 20211008 PID PID:200220 18406889 RUNX2 RUNX family transcription factor 2 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1348975 W RGD:9068941 20211008 RGD PMID:16322555|PMID:18061509|REF_RGD_ID:2302137|REF_RGD_ID:5143919 18406934 HNF1A HNF1 homeobox A gene PW:0000958 forkhead class A signaling pathway ISO RGD:737153 W RGD:9068941 20211008 PID PID:200087 18407027 RPL10A ribosomal protein L10a gene PW:0000101 translation pathway ISO RGD:732410 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18407027 RPL10A ribosomal protein L10a gene PW:0001066 ribosome biogenesis pathway ISO RGD:732410 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18407173 CNOT1 CCR4-NOT transcription complex subunit 1 gene PW:0000808 microRNA pathway ISO RGD:1602129 W RGD:9068941 20211008 RGD PMID:23337855|REF_RGD_ID:9850101 18407241 RPL26 ribosomal protein L26 gene PW:0000101 translation pathway ISO RGD:1321610 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18407241 RPL26 ribosomal protein L26 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1321610 W RGD:9068941 20211008 RGD PMID:23636399|PMID:25346433|REF_RGD_ID:10002762|REF_RGD_ID:9999448 18407648 STIM1 stromal interaction molecule 1 gene PW:0001139 calcium transport pathway ISO RGD:1315668 W RGD:9068941 20211008 RGD PMID:22914293|REF_RGD_ID:7204692 18407648 STIM1 stromal interaction molecule 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1315668 W RGD:9068941 20211008 RGD PMID:22914293|REF_RGD_ID:7204692 18407762 CUL7 cullin 7 gene PW:0000415 proteasome degradation pathway involving cullin-dependent ubiquitin ligases ISO RGD:1314380 W RGD:9068941 20211008 RGD PMID:12481031|REF_RGD_ID:1559286 18407762 CUL7 cullin 7 gene PW:0000435 neddylation pathway ISO RGD:1314380 W RGD:9068941 20211008 RGD PMID:15021886|REF_RGD_ID:1559277 18407812 LRRC7 leucine rich repeat containing 7 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:1349743 W RGD:9068941 20211008 RGD PMID:22717267|REF_RGD_ID:7240705 18408002 JAK1 Janus kinase 1 gene PW:0000209 Jak-Stat signaling pathway ISO RGD:69056 W RGD:9068941 20211008 RGD PMID:12087100|REF_RGD_ID:1299183 18408002 JAK1 Janus kinase 1 gene PW:0000209 Jak-Stat signaling pathway ISO RGD:69102 W RGD:9068941 20211008 RGD PMID:12039028|PMID:17312100|REF_RGD_ID:1357935|REF_RGD_ID:1625126 18408002 JAK1 Janus kinase 1 gene PW:0000209 Jak-Stat signaling pathway ISO RGD:69103 W RGD:9068941 20211008 RGD PMID:17312100|REF_RGD_ID:1625126 18408002 JAK1 Janus kinase 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:69102 W RGD:9068941 20211008 PID PID:200162 18408002 JAK1 Janus kinase 1 gene PW:0000368 Non-Stat, Jak dependent pathway ISO RGD:69102 W RGD:9068941 20211008 RGD PMID:12884916|REF_RGD_ID:1357942 18408002 JAK1 Janus kinase 1 gene PW:0000515 Interleukin-10 signaling pathway ISO RGD:69102 W RGD:9068941 20211008 RGD PMID:21115385|REF_RGD_ID:5688379 18408002 JAK1 Janus kinase 1 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:69102 W RGD:9068941 20211008 PID PID:200146 18408002 JAK1 Janus kinase 1 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:69102 W RGD:9068941 20211008 RGD PMID:21881215|REF_RGD_ID:5686839 18408002 JAK1 Janus kinase 1 gene PW:0000896 type II interferon signaling pathway ISO RGD:69102 W RGD:9068941 20211008 PID PID:200129 18408002 JAK1 Janus kinase 1 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:69102 W RGD:9068941 20211008 PID PID:200098 18408002 JAK1 Janus kinase 1 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:69102 W RGD:9068941 20211008 PID PID:200022 18408002 JAK1 Janus kinase 1 gene PW:0000916 interleukin-27 signaling pathway ISO RGD:69102 W RGD:9068941 20211008 PID PID:200028 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:733234 W RGD:9068941 20211008 RGD PMID:23841840|REF_RGD_ID:8549585 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00296 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0000856 acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family ISO RGD:733234 W RGD:9068941 20211008 RGD PMID:23841840|REF_RGD_ID:8549585 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00379 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00665 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00376 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00375 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00659 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00660 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00323 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00307 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00324 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00380 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00381 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00382 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00366 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00302 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00378 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00332 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00331 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00301 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00325 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00359 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002134 bupranolol drug pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00670 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00670 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00300 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00299 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00296 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00298 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00305 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00303 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00306 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00326 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00666 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00327 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00329 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00662 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00663 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00328 18408031 CHRM2 cholinergic receptor muscarinic 2 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:733234 W RGD:9068941 20211008 SMPDB SMP:00367 18408110 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1321121 W RGD:9068941 20211008 PID PID:200149 18408110 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 gene PW:0000718 p53 signaling pathway ISO RGD:1321121 W RGD:9068941 20211008 PID PID:200206 18408110 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 gene PW:0000718 p53 signaling pathway ISO RGD:1321121 W RGD:9068941 20211008 RGD PMID:20679336|REF_RGD_ID:8662965 18408110 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 gene PW:0000720 altered p53 signaling pathway ISO RGD:1321121 W RGD:9068941 20211008 RGD PMID:22713868|REF_RGD_ID:8663430 18408251 NANOG Nanog homeobox gene PW:0001340 DNA modification pathway ISO RGD:1347686 W RGD:9068941 20211008 RGD PMID:24825349|REF_RGD_ID:8695944 18408345 HK3 hexokinase 3 gene PW:0000640 glycolysis pathway ISO RGD:2798 W RGD:9068941 20211008 RGD PMID:9540816|REF_RGD_ID:2302784 18408372 TFPI tissue factor pathway inhibitor gene PW:0000474 coagulation cascade pathway ISO RGD:1344546 W RGD:9068941 20211008 RGD PMID:12787532|PMID:26018600|REF_RGD_ID:11342779|REF_RGD_ID:11352277 18408372 TFPI tissue factor pathway inhibitor gene PW:0000659 syndecan signaling pathway ISO RGD:1344546 W RGD:9068941 20211008 PID PID:200134 18408395 TAF15 TATA-box binding protein associated factor 15 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1320016 W RGD:9068941 20211008 RGD PMID:23146842|REF_RGD_ID:9681723 18408676 RPL28 ribosomal protein L28 gene PW:0000101 translation pathway ISO RGD:733961 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18408676 RPL28 ribosomal protein L28 gene PW:0001066 ribosome biogenesis pathway ISO RGD:733961 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18408721 TTF1 transcription termination factor 1 gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1558173 W RGD:9068941 20211008 RGD PMID:23092677|REF_RGD_ID:9588249 18408769 GRHPR glyoxylate and hydroxypyruvate reductase gene PW:0000043 pyruvate metabolic pathway ISO RGD:1318860 W RGD:9068941 20211008 SMPDB SMP:00060 18408769 GRHPR glyoxylate and hydroxypyruvate reductase gene PW:0001416 Leigh disease pathway ISO RGD:1318860 W RGD:9068941 20211008 SMPDB SMP:00196 18408769 GRHPR glyoxylate and hydroxypyruvate reductase gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:1318860 W RGD:9068941 20211008 SMPDB SMP:00559 18408769 GRHPR glyoxylate and hydroxypyruvate reductase gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:1318860 W RGD:9068941 20211008 SMPDB SMP:00212 18408769 GRHPR glyoxylate and hydroxypyruvate reductase gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:1318860 W RGD:9068941 20211008 SMPDB SMP:00334 18408769 GRHPR glyoxylate and hydroxypyruvate reductase gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:1318860 W RGD:9068941 20211008 SMPDB SMP:00558 18408818 ADK adenosine kinase gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:737582 W RGD:9068941 20211008 SMPDB SMP:00609 18408818 ADK adenosine kinase gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:737582 W RGD:9068941 20211008 SMPDB SMP:00428 18408818 ADK adenosine kinase gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:737582 W RGD:9068941 20211008 SMPDB SMP:00427 18408818 ADK adenosine kinase gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:737582 W RGD:9068941 20211008 SMPDB SMP:00430 18408883 PINK1 PTEN induced kinase 1 gene PW:0000018 Parkinson's disease pathway ISO RGD:1314001 W RGD:9068941 20211008 RGD PMID:24735649|PMID:25639775|PMID:26223426|REF_RGD_ID:10450518|REF_RGD_ID:10450521|REF_RGD_ID:10450527 18408883 PINK1 PTEN induced kinase 1 gene PW:0001842 mitochondrial autophagy pathway ISO RGD:1314001 W RGD:9068941 20211008 RGD PMID:23065344|PMID:25840011|PMID:25995186|REF_RGD_ID:10400888|REF_RGD_ID:10401098|REF_RGD_ID:10401790 18408883 PINK1 PTEN induced kinase 1 gene PW:0001958 altered mitochondrial autophagy pathway ISO RGD:1314001 W RGD:9068941 20211008 RGD PMID:24735649|REF_RGD_ID:10450527 18408883 PINK1 PTEN induced kinase 1 gene PW:0001961 mitochondria dynamics pathway ISO RGD:1305769 W RGD:9068941 20211008 RGD PMID:21613270|REF_RGD_ID:12903967 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000022 cardiomyopathy pathway ISO RGD:1552419 W RGD:9068941 20211008 RGD PMID:15722372|REF_RGD_ID:1582275 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:620666 W RGD:9068941 20211008 RGD PMID:16183734|REF_RGD_ID:2298758 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:732805 W RGD:9068941 20211008 PID PID:200018 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:732805 W RGD:9068941 20211008 RGD PMID:17481747|REF_RGD_ID:2293891 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:732805 W RGD:9068941 20211008 PID PID:200188 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:732805 W RGD:9068941 20211008 PID PID:200146 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000681 FasL mediated signaling pathway ISO RGD:732805 W RGD:9068941 20211008 PID PID:200080 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:732805 W RGD:9068941 20211008 PID PID:200089 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:732805 W RGD:9068941 20211008 PID PID:200045 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0000998 adenosine signaling pathway ISO RGD:732805 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18409036 MAP2K6 mitogen-activated protein kinase kinase 6 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:732805 W RGD:9068941 20211008 SMPDB SMP:00358 18409144 LOC103216037 cadherin-23 gene PW:0001497 retinitis pigmentosa pathway ISO RGD:733851 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18409144 LOC103216037 cadherin-23 gene PW:0001503 auditory mechanotransduction pathway ISO RGD:733851 W RGD:9068941 20211008 RGD PMID:19804752|PMID:22177415|REF_RGD_ID:8547667|REF_RGD_ID:8547671 18409353 RPS13 ribosomal protein S13 gene PW:0000101 translation pathway ISO RGD:737303 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18409353 RPS13 ribosomal protein S13 gene PW:0001066 ribosome biogenesis pathway ISO RGD:737303 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18409539 ST13 ST13 Hsp70 interacting protein gene PW:0000564 androgen signaling pathway ISO RGD:733794 W RGD:9068941 20211008 RGD PMID:16356826|REF_RGD_ID:2326084 18409539 ST13 ST13 Hsp70 interacting protein gene PW:0002401 chaperone mediated autophagy pathway ISO RGD:733794 W RGD:9068941 20211008 RGD PMID:25724482|REF_RGD_ID:10755685 18409644 CTSL cathepsin L gene PW:0002401 chaperone mediated autophagy pathway ISO RGD:736036 W RGD:9068941 20211008 RGD PMID:24323530|REF_RGD_ID:10755730 18409721 RPP25 ribonuclease P and MRP subunit p25 gene PW:0001573 tRNA maturation pathway ISO RGD:1313231 W RGD:9068941 20211008 RGD PMID:19931535|REF_RGD_ID:9685326 18409745 PDGFC platelet derived growth factor C gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:68605 W RGD:9068941 20211008 PID PID:200201 18409768 RPS6KA1 ribosomal protein S6 kinase A1 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:732451 W RGD:9068941 20211008 RGD PMID:16421520|REF_RGD_ID:2315047 18409768 RPS6KA1 ribosomal protein S6 kinase A1 gene PW:0000180 mTOR signaling pathway ISO RGD:732451 W RGD:9068941 20211008 PID PID:200096 18409768 RPS6KA1 ribosomal protein S6 kinase A1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:732451 W RGD:9068941 20211008 PID PID:200220 18409768 RPS6KA1 ribosomal protein S6 kinase A1 gene PW:0000998 adenosine signaling pathway ISO RGD:732451 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18409856 COL8A1 collagen type VIII alpha 1 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1319668 W RGD:9068941 20211008 PID PID:200156 18410001 LOC103219433 nuclear factor 1 B-type gene PW:0000958 forkhead class A signaling pathway ISO RGD:733820 W RGD:9068941 20211008 PID PID:200226 18410070 FADS1 fatty acid desaturase 1 gene PW:0000523 linoleic acid metabolic pathway ISO RGD:1344024 W RGD:9068941 20211008 SMPDB SMP:00018 18410070 FADS1 fatty acid desaturase 1 gene PW:0001158 alpha-linolenic acid metabolic pathway ISO RGD:1344024 W RGD:9068941 20211008 SMPDB SMP:00018 18410291 TP53BP2 tumor protein p53 binding protein 2 gene PW:0000718 p53 signaling pathway ISO RGD:1313500 W RGD:9068941 20211008 RGD PMID:20679336|REF_RGD_ID:8662965 18410431 RBMX RNA binding motif protein X-linked gene PW:0001073 spliceosome pathway ISO RGD:1349812 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18410457 LOC103241092 tyrosine-protein kinase ZAP-70 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:1349191 W RGD:9068941 20211008 PID PID:200116 18410577 CYP1B1 cytochrome P450 family 1 subfamily B member 1 gene PW:0000375 phase I biotransformation pathway via cytochrome P450 ISO RGD:2460 W RGD:9068941 20211008 RGD PMID:7744798|REF_RGD_ID:728267 18410589 SETD7 SET domain containing 7, histone lysine methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1606498 W RGD:9068941 20211008 RGD PMID:22194015|REF_RGD_ID:7242554 18410589 SETD7 SET domain containing 7, histone lysine methyltransferase gene PW:0000718 p53 signaling pathway ISO RGD:1606498 W RGD:9068941 20211008 PID PID:200206 18410589 SETD7 SET domain containing 7, histone lysine methyltransferase gene PW:0000718 p53 signaling pathway ISO RGD:1606498 W RGD:9068941 20211008 RGD PMID:19450511|REF_RGD_ID:2316155 18410589 SETD7 SET domain containing 7, histone lysine methyltransferase gene PW:0001338 histone modification pathway ISO RGD:1606498 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18410589 SETD7 SET domain containing 7, histone lysine methyltransferase gene PW:0002292 carnitine biosynthetic pathway ISO RGD:1606498 W RGD:9068941 20211008 SMPDB SMP:00465 18410692 SIRT1 sirtuin 1 gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1318374 W RGD:9068941 20211008 RGD PMID:24022641|REF_RGD_ID:9588250 18410692 SIRT1 sirtuin 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1318374 W RGD:9068941 20211008 PID PID:200036 18410692 SIRT1 sirtuin 1 gene PW:0000718 p53 signaling pathway ISO RGD:1318374 W RGD:9068941 20211008 RGD PMID:19450511|REF_RGD_ID:2316155 18410692 SIRT1 sirtuin 1 gene PW:0001338 histone modification pathway ISO RGD:1318374 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18410692 SIRT1 sirtuin 1 gene PW:0002584 Sirtuin mediated pathway ISO RGD:1318374 W RGD:9068941 20211008 RGD PMID:26785480|REF_RGD_ID:11100032 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:621283 W RGD:9068941 20211008 RGD PMID:15845641|REF_RGD_ID:1359026 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 RGD PMID:20814827|PMID:23073625|REF_RGD_ID:7242425|REF_RGD_ID:7242426 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00033 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000140 folate metabolic pathway ISO RGD:621283 W RGD:9068941 20211008 RGD PMID:15845641|REF_RGD_ID:1359026 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:621283 W RGD:9068941 20211008 RGD PMID:15845641|REF_RGD_ID:1359026 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 RGD PMID:20814827|REF_RGD_ID:7242426 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000212 choline metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00123 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000399 remethylation pathway of homocysteine metabolism - cobalamin dependent ISO RGD:621283 W RGD:9068941 20211008 RGD PMID:15845641|REF_RGD_ID:1359026 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000399 remethylation pathway of homocysteine metabolism - cobalamin dependent ISO RGD:731933 W RGD:9068941 20211008 RGD PMID:20814827|REF_RGD_ID:7242426 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00123 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0001207 folate cycle metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0001208 altered folate cycle metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0001209 altered folate mediated one-carbon metabolic pathway ISO RGD:731933 W RGD:9068941 20211008 RGD PMID:22353665|REF_RGD_ID:7242562 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0001841 homocystinuria pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00177 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0001868 hypermethioninemia pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00221 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00222 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00340 18410732 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase gene PW:0002471 hypermethioninemia pathway ISO RGD:731933 W RGD:9068941 20211008 SMPDB SMP:00341 18410865 PTCH2 patched 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:1604843 W RGD:9068941 20211008 PID PID:200168 18410865 PTCH2 patched 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:1604843 W RGD:9068941 20211008 RGD PMID:20635334|PMID:20716670|REF_RGD_ID:5510013|REF_RGD_ID:5510026 18410950 RARB retinoic acid receptor beta gene PW:0001014 retinoic acid signaling pathway ISO RGD:737497 W RGD:9068941 20211008 RGD PMID:17132850|PMID:17320364|PMID:19471584|REF_RGD_ID:6484674|REF_RGD_ID:6484676|REF_RGD_ID:6484731 18410965 CALM1 calmodulin 1 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:735369 W RGD:9068941 20211008 PID PID:200018 18410965 CALM1 calmodulin 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:735369 W RGD:9068941 20211008 PID PID:200188 18410965 CALM1 calmodulin 1 gene PW:0000534 glycogen degradation pathway ISO RGD:735369 W RGD:9068941 20211008 RGD PMID:10487978|REF_RGD_ID:2305981 18410965 CALM1 calmodulin 1 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:735369 W RGD:9068941 20211008 RGD PMID:16054095|REF_RGD_ID:2311420 18410965 CALM1 calmodulin 1 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:735369 W RGD:9068941 20211008 PID PID:200196 18410965 CALM1 calmodulin 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00296 18410965 CALM1 calmodulin 1 gene PW:0000896 type II interferon signaling pathway ISO RGD:735369 W RGD:9068941 20211008 PID PID:200129 18410965 CALM1 calmodulin 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:735369 W RGD:9068941 20211008 PID PID:200209 18410965 CALM1 calmodulin 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:735369 W RGD:9068941 20211008 RGD PMID:10884684|PMID:18083096|REF_RGD_ID:7204676|REF_RGD_ID:7204677 18410965 CALM1 calmodulin 1 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:735369 W RGD:9068941 20211008 RGD PMID:22717267|PMID:23091085|REF_RGD_ID:7240705|REF_RGD_ID:7240708 18410965 CALM1 calmodulin 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00379 18410965 CALM1 calmodulin 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00665 18410965 CALM1 calmodulin 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00376 18410965 CALM1 calmodulin 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00375 18410965 CALM1 calmodulin 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00659 18410965 CALM1 calmodulin 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00660 18410965 CALM1 calmodulin 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00323 18410965 CALM1 calmodulin 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00307 18410965 CALM1 calmodulin 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00324 18410965 CALM1 calmodulin 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00380 18410965 CALM1 calmodulin 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00381 18410965 CALM1 calmodulin 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00382 18410965 CALM1 calmodulin 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00366 18410965 CALM1 calmodulin 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00302 18410965 CALM1 calmodulin 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00378 18410965 CALM1 calmodulin 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00332 18410965 CALM1 calmodulin 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00331 18410965 CALM1 calmodulin 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00301 18410965 CALM1 calmodulin 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00325 18410965 CALM1 calmodulin 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00359 18410965 CALM1 calmodulin 1 gene PW:0002134 bupranolol drug pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00670 18410965 CALM1 calmodulin 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00670 18410965 CALM1 calmodulin 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00300 18410965 CALM1 calmodulin 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00299 18410965 CALM1 calmodulin 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00296 18410965 CALM1 calmodulin 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00298 18410965 CALM1 calmodulin 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00305 18410965 CALM1 calmodulin 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00303 18410965 CALM1 calmodulin 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00306 18410965 CALM1 calmodulin 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00326 18410965 CALM1 calmodulin 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00666 18410965 CALM1 calmodulin 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00327 18410965 CALM1 calmodulin 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00329 18410965 CALM1 calmodulin 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00662 18410965 CALM1 calmodulin 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00663 18410965 CALM1 calmodulin 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00328 18410965 CALM1 calmodulin 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:735369 W RGD:9068941 20211008 SMPDB SMP:00367 18411184 NFE2L2 NFE2 like bZIP transcription factor 2 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:734431 W RGD:9068941 20211008 RGD PMID:24647116|PMID:25937177|PMID:26419687|REF_RGD_ID:11530066|REF_RGD_ID:11535066|REF_RGD_ID:11535070 18411184 NFE2L2 NFE2 like bZIP transcription factor 2 gene PW:0000378 oxidative stress response pathway ISO RGD:620360 W RGD:9068941 20211008 RGD PMID:29091898|REF_RGD_ID:15090820 18411196 CALCOCO1 calcium binding and coiled-coil domain 1 gene PW:0000507 estrogen signaling pathway ISO RGD:731717 W RGD:9068941 20211008 RGD PMID:16394250|REF_RGD_ID:5128512 18411409 CASP7 caspase 7 gene PW:0000104 intrinsic apoptotic pathway ISO RGD:1298347 W RGD:9068941 20211008 RGD PMID:17082813|REF_RGD_ID:2314187 18411409 CASP7 caspase 7 gene PW:0000106 extrinsic apoptotic pathway ISO RGD:1298347 W RGD:9068941 20211008 RGD PMID:17082813|REF_RGD_ID:2314187 18411409 CASP7 caspase 7 gene PW:0000134 glutathione metabolic pathway ISO RGD:1298347 W RGD:9068941 20211008 SMPDB SMP:00015 18411409 CASP7 caspase 7 gene PW:0000681 FasL mediated signaling pathway ISO RGD:1298347 W RGD:9068941 20211008 RGD PMID:19239902|REF_RGD_ID:4143196 18411409 CASP7 caspase 7 gene PW:0000682 Trail mediated signaling pathway ISO RGD:1298347 W RGD:9068941 20211008 RGD PMID:19961901|REF_RGD_ID:4143171 18411409 CASP7 caspase 7 gene PW:0002019 glutathione synthase deficiency pathway ISO RGD:1298347 W RGD:9068941 20211008 SMPDB SMP:00143|SMP:00337 18411409 CASP7 caspase 7 gene PW:0002562 glutathionuria disease pathway ISO RGD:1298347 W RGD:9068941 20211008 SMPDB SMP:00501 18411533 CARNS1 carnosine synthase 1 gene PW:0000051 histidine metabolic pathway ISO RGD:2301770 W RGD:9068941 20211008 SMPDB SMP:00044 18411533 CARNS1 carnosine synthase 1 gene PW:0001978 histidinemia pathway ISO RGD:2301770 W RGD:9068941 20211008 SMPDB SMP:00191 18411614 PALB2 partner and localizer of BRCA2 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1605949 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18411630 LOC103234962 caspase recruitment domain-containing protein 8 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1351599 W RGD:9068941 20211008 RGD PMID:19302047|REF_RGD_ID:5490210 18411887 MED13L mediator complex subunit 13L gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1314183 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18411947 EIF3H eukaryotic translation initiation factor 3 subunit H gene PW:0000580 translation initiation pathway ISO RGD:1351668 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18412284 ETFB electron transfer flavoprotein subunit beta gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1347524 W RGD:9068941 20211008 RGD PMID:14728676|REF_RGD_ID:2317589 18412468 MAFG MAF bZIP transcription factor G gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1352039 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18412620 NUDT16L1 nudix hydrolase 16 like 1 gene PW:0000659 syndecan signaling pathway ISO RGD:1342997 W RGD:9068941 20211008 PID PID:200134 18412689 THTPA thiamine triphosphatase gene PW:0000136 thiamine metabolic pathway ISO RGD:1344933 W RGD:9068941 20211008 SMPDB SMP:00076 18412805 IGFALS insulin like growth factor binding protein acid labile subunit gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:68640 W RGD:9068941 20211008 RGD PMID:15862547|REF_RGD_ID:1626333 18412858 PDE6G phosphodiesterase 6G gene PW:0000962 visual phototransduction pathway ISO RGD:735391 W RGD:9068941 20211008 RGD PMID:15224133|REF_RGD_ID:6893540 18412858 PDE6G phosphodiesterase 6G gene PW:0001495 altered visual phototransduction pathway ISO RGD:735391 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18412858 PDE6G phosphodiesterase 6G gene PW:0001497 retinitis pigmentosa pathway ISO RGD:735391 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18412875 RPL19 ribosomal protein L19 gene PW:0000101 translation pathway ISO RGD:734460 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18412875 RPL19 ribosomal protein L19 gene PW:0001066 ribosome biogenesis pathway ISO RGD:734460 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18413044 TCF7L1 transcription factor 7 like 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1323252 W RGD:9068941 20211008 RGD PMID:10528152|REF_RGD_ID:2301908 18413138 MED21 mediator complex subunit 21 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1320392 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18413233 EIF3F eukaryotic translation initiation factor 3 subunit F gene PW:0000580 translation initiation pathway ISO RGD:1314535 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18413369 CLP1 cleavage factor polyribonucleotide kinase subunit 1 gene PW:0001332 RNA polymerase II transcription termination pathway ISO RGD:1602724 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18413369 CLP1 cleavage factor polyribonucleotide kinase subunit 1 gene PW:0001573 tRNA maturation pathway ISO RGD:1602724 W RGD:9068941 20211008 RGD PMID:25071838|REF_RGD_ID:9685342 18413369 CLP1 cleavage factor polyribonucleotide kinase subunit 1 gene PW:0001579 3'-end pre-mRNA processing pathway ISO RGD:1602724 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18413376 COL13A1 collagen type XIII alpha 1 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1607090 W RGD:9068941 20211008 PID PID:200156 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00296 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00379 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00665 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00376 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00375 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00659 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00660 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00323 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00307 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00324 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00380 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00381 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00382 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00366 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00302 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00378 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00332 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00331 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00301 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00325 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00359 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002134 bupranolol drug pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00670 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00670 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00300 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00299 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00296 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00298 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00305 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00303 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00306 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00326 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00666 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00327 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00329 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00662 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00663 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00328 18413468 TNNT3 troponin T3, fast skeletal type gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:737137 W RGD:9068941 20211008 SMPDB SMP:00367 18413568 SLC1A4 solute carrier family 1 member 4 gene PW:0000076 urea cycle pathway ISO RGD:1345199 W RGD:9068941 20211008 SMPDB SMP:00059 18413568 SLC1A4 solute carrier family 1 member 4 gene PW:0001806 ornithine carbamoyltransferase deficiency pathway ISO RGD:1345199 W RGD:9068941 20211008 SMPDB SMP:00205 18413568 SLC1A4 solute carrier family 1 member 4 gene PW:0002143 citrullinemia pathway ISO RGD:1345199 W RGD:9068941 20211008 SMPDB SMP:00001 18413568 SLC1A4 solute carrier family 1 member 4 gene PW:0002145 argininosuccinic aciduria pathway ISO RGD:1345199 W RGD:9068941 20211008 SMPDB SMP:00003 18413568 SLC1A4 solute carrier family 1 member 4 gene PW:0002220 carbamoyl phosphate synthetase I deficiency pathway ISO RGD:1345199 W RGD:9068941 20211008 SMPDB SMP:00002 18413568 SLC1A4 solute carrier family 1 member 4 gene PW:0002290 hyperargininemia pathway ISO RGD:1345199 W RGD:9068941 20211008 SMPDB SMP:00357 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00075 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0000462 lipoxygenase mediated pathway of arachidonic acid metabolism ISO RGD:2096 W RGD:9068941 20211008 RGD PMID:15107407|REF_RGD_ID:1578311 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0000462 lipoxygenase mediated pathway of arachidonic acid metabolism ISO RGD:732775 W RGD:9068941 20211008 RGD PMID:17517102|REF_RGD_ID:2313910 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0000464 leukotriene metabolic pathway ISO RGD:2096 W RGD:9068941 20211008 RGD PMID:7665580|REF_RGD_ID:39128168 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0000464 leukotriene metabolic pathway ISO RGD:732775 W RGD:9068941 20211008 RGD PMID:17517102|REF_RGD_ID:2313910 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00096 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00086 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001524 paracetamol drug pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00710 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00083 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001665 antipyrine drug pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00692 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00116 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00704 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00706 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00094 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00077 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00120 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00114 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00106 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00109 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00098 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00085 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00084 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00289 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00093 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00696 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00104 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00104 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00700 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00709 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00708 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00353 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00705 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00697 18413804 ALOX5 arachidonate 5-lipoxygenase gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:732775 W RGD:9068941 20211008 SMPDB SMP:00698 18413827 WNT7A Wnt family member 7A gene PW:0000008 Wnt signaling pathway ISO RGD:69159 W RGD:9068941 20211008 RGD 18413827 WNT7A Wnt family member 7A gene PW:0000008 Wnt signaling pathway ISO RGD:69160 W RGD:9068941 20211008 RGD 18413827 WNT7A Wnt family member 7A gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:3258 W RGD:9068941 20211008 RGD PMID:16164600|REF_RGD_ID:1601222 18413827 WNT7A Wnt family member 7A gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:69159 W RGD:9068941 20211008 RGD PMID:18765832|REF_RGD_ID:2313743 18413827 WNT7A Wnt family member 7A gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:69079 W RGD:9068941 20211008 RGD PMID:18567805|REF_RGD_ID:4107045 18413868 CDK9 cyclin dependent kinase 9 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1346548 W RGD:9068941 20211008 RGD pol II carboxyl-terminal domain (CTD) PMID:22622228|PMID:23837720|REF_RGD_ID:9681737|REF_RGD_ID:9681738 18413868 CDK9 cyclin dependent kinase 9 gene PW:0001331 RNA polymerase II transcription elongation pathway ISO RGD:1346548 W RGD:9068941 20211008 RGD PMID:24050178|REF_RGD_ID:9681735 18413879 MRM2 mitochondrial rRNA methyltransferase 2 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1314273 W RGD:9068941 20211008 RGD PMID:11827451|REF_RGD_ID:1359074 18413953 KMT2D lysine methyltransferase 2D gene PW:0001338 histone modification pathway ISO RGD:1350607 W RGD:9068941 20211008 RGD PMID:22663077|PMID:23200123|REF_RGD_ID:7242632|REF_RGD_ID:9479053 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000043 pyruvate metabolic pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00060 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000058 fatty acid metabolic pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00051 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000064 propanoate metabolic pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00016 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000065 butanoate metabolic pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00073 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000069 ketone bodies metabolic pathway ISO RGD:737017 W RGD:9068941 20211008 RGD PMID:15877199|REF_RGD_ID:2326093 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000069 ketone bodies metabolic pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00071 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00032 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000073 lysine degradation pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00037 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00480 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001416 Leigh disease pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00196 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001594 very long-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00540 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001627 trifunctional protein deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00545 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001667 short-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00235 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001668 3-hydroxyacyl-CoA dehydrogenase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00568 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001703 saccharopinuria pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00239|SMP:00528 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00559 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00212 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00334 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001778 propionic acidemia pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00236 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00558 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00384 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001810 methylmalonic acidemia pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00200 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001811 methylmalonic aciduria, cobalamin-related pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00201 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001869 medium chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00542 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001870 maple syrup urine disease pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00199 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001874 isovaleric acidemia pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00523 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0001936 hyperlysinemia pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00527 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002204 2-aminoadipic 2-oxoadipic aciduria pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00719 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002206 ethylmalonic encephalopathy pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00181 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00139 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00140 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002289 malonic aciduria pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00198|SMP:00502 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002306 glutaric aciduria type I pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00185|SMP:00186 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00138 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002549 succinyl-CoA:3-oxoacid transferase deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00569 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002574 carnitine palmitoyltransferase I deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00538 18414087 ACAT1 acetyl-CoA acetyltransferase 1 gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:737017 W RGD:9068941 20211008 SMPDB SMP:00237 18414204 COL2A1 collagen type II alpha 1 chain gene PW:0000659 syndecan signaling pathway ISO RGD:734037 W RGD:9068941 20211008 PID PID:200156 18414271 ELL3 elongation factor for RNA polymerase II 3 gene PW:0001331 RNA polymerase II transcription elongation pathway ISO RGD:1320517 W RGD:9068941 20211008 RGD PMID:22895430|REF_RGD_ID:9681740 18414406 GMPR guanosine monophosphate reductase gene PW:0000031 purine metabolic pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00050 18414406 GMPR guanosine monophosphate reductase gene PW:0001590 xanthinuria pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00220 18414406 GMPR guanosine monophosphate reductase gene PW:0001591 xanthinuria type I pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00512 18414406 GMPR guanosine monophosphate reductase gene PW:0001592 xanthinuria type II pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00513 18414406 GMPR guanosine monophosphate reductase gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00210 18414406 GMPR guanosine monophosphate reductase gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00537 18414406 GMPR guanosine monophosphate reductase gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00203 18414406 GMPR guanosine monophosphate reductase gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00364 18414406 GMPR guanosine monophosphate reductase gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00365 18414406 GMPR guanosine monophosphate reductase gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00428 18414406 GMPR guanosine monophosphate reductase gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00427 18414406 GMPR guanosine monophosphate reductase gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00167 18414406 GMPR guanosine monophosphate reductase gene PW:0002294 AICA-ribosuria pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00168 18414406 GMPR guanosine monophosphate reductase gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00430 18414406 GMPR guanosine monophosphate reductase gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:733310 W RGD:9068941 20211008 SMPDB SMP:00535 18414457 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta gene PW:0000180 mTOR signaling pathway ISO RGD:734393 W RGD:9068941 20211008 PID PID:200096 18414457 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:734393 W RGD:9068941 20211008 PID PID:200197 18414457 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:734393 W RGD:9068941 20211008 PID PID:200149 18414457 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:734393 W RGD:9068941 20211008 PID PID:200196 18414467 WASL WASP like actin nucleation promoting factor gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1347655 W RGD:9068941 20211008 PID PID:200101 18414467 WASL WASP like actin nucleation promoting factor gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1347655 W RGD:9068941 20211008 PID PID:200149 18414467 WASL WASP like actin nucleation promoting factor gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1347655 W RGD:9068941 20211008 PID PID:200052 18414854 LRP4 LDL receptor related protein 4 gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:1331974 W RGD:9068941 20211008 RGD PMID:23032192|REF_RGD_ID:8549508 18415176 RAD51B RAD51 paralog B gene PW:0000202 homologous recombination pathway of double-strand break repair ISO RGD:1344706 W RGD:9068941 20211008 RGD PMID:20690856|REF_RGD_ID:8662366 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000047 glycine, serine and threonine metabolic pathway ISO RGD:1312011 W RGD:9068941 20211008 RGD PMID:3110140|REF_RGD_ID:2300383 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000047 glycine, serine and threonine metabolic pathway ISO RGD:1323770 W RGD:9068941 20211008 RGD PMID:15671219|REF_RGD_ID:1359815 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00033 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000140 folate metabolic pathway ISO RGD:1323770 W RGD:9068941 20211008 RGD PMID:15671219|REF_RGD_ID:1359815 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:1312011 W RGD:9068941 20211008 RGD PMID:3110140|REF_RGD_ID:2300383 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:1323770 W RGD:9068941 20211008 RGD PMID:15671219|PMID:22332074|REF_RGD_ID:1359815|REF_RGD_ID:7242561 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0000440 glycine metabolic pathway ISO RGD:1312011 W RGD:9068941 20211008 RGD PMID:3110140|REF_RGD_ID:2300383 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0001207 folate cycle metabolic pathway ISO RGD:1323770 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0001670 sarcosinemia pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00244 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0001841 homocystinuria pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00177 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0001868 hypermethioninemia pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00221 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00179 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0002292 carnitine biosynthetic pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00465 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00222 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00340 18415297 SHMT1 serine hydroxymethyltransferase 1 gene PW:0002471 hypermethioninemia pathway ISO RGD:1323770 W RGD:9068941 20211008 SMPDB SMP:00341 18415328 SF3B2 splicing factor 3b subunit 2 gene PW:0001073 spliceosome pathway ISO RGD:1316185 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18415447 EDN1 endothelin 1 gene PW:0000024 inflammatory response pathway ISO RGD:2532 W RGD:9068941 20211008 RGD PMID:20409845|REF_RGD_ID:4892591 18415447 EDN1 endothelin 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:730848 W RGD:9068941 20211008 PID PID:200202 18415447 EDN1 endothelin 1 gene PW:0000506 endothelin signaling pathway ISO RGD:730848 W RGD:9068941 20211008 PID PID:200005 18415447 EDN1 endothelin 1 gene PW:0000506 endothelin signaling pathway ISO RGD:730848 W RGD:9068941 20211008 RGD PMID:15124920|REF_RGD_ID:1580323 18415461 PDE4A phosphodiesterase 4A gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:737080 W RGD:9068941 20211008 RGD PMID:17376027|REF_RGD_ID:2312479 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:732809 W RGD:9068941 20211008 SMPDB SMP:00064 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000640 glycolysis pathway ISO RGD:11083 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000640 glycolysis pathway ISO RGD:3307 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000640 glycolysis pathway ISO RGD:732809 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:11083 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:3307 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:732809 W RGD:9068941 20211008 RGD PMID:15170386|REF_RGD_ID:2302793 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:732809 W RGD:9068941 20211008 SMPDB SMP:00725 18415891 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene PW:0002388 fructosuria pathway ISO RGD:732809 W RGD:9068941 20211008 SMPDB SMP:00561 18415942 PRICKLE1 prickle planar cell polarity protein 1 gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1618248 W RGD:9068941 20211008 RGD PMID:17226800|REF_RGD_ID:2293492 18415978 PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 gene PW:0000143 insulin signaling pathway ISO RGD:1353016 W RGD:9068941 20211008 SMPDB SMP:00391 18415978 PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1353016 W RGD:9068941 20211008 PID PID:200149 18415978 PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1353016 W RGD:9068941 20211008 PID PID:200142 18415978 PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 gene PW:0000565 eicosanoid signaling pathway ISO RGD:1353016 W RGD:9068941 20211008 PID PID:200082 18415978 PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:1353016 W RGD:9068941 20211008 PID PID:200116 18416023 CHRM4 cholinergic receptor muscarinic 4 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:68976 W RGD:9068941 20211008 RGD PMID:23841840|REF_RGD_ID:8549585 18416023 CHRM4 cholinergic receptor muscarinic 4 gene PW:0000856 acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family ISO RGD:68976 W RGD:9068941 20211008 RGD PMID:23841840|REF_RGD_ID:8549585 18416032 GPT glutamic--pyruvic transaminase gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00072 18416032 GPT glutamic--pyruvic transaminase gene PW:0000076 urea cycle pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00059 18416032 GPT glutamic--pyruvic transaminase gene PW:0000438 alanine metabolic pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00055 18416032 GPT glutamic--pyruvic transaminase gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18416032 GPT glutamic--pyruvic transaminase gene PW:0001775 pyruvate carboxylase deficiency pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00350 18416032 GPT glutamic--pyruvic transaminase gene PW:0001782 primary hyperoxaluria type 1 pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00352 18416032 GPT glutamic--pyruvic transaminase gene PW:0001806 ornithine carbamoyltransferase deficiency pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00205 18416032 GPT glutamic--pyruvic transaminase gene PW:0001979 homocarnosinosis pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00385 18416032 GPT glutamic--pyruvic transaminase gene PW:0002143 citrullinemia pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00001 18416032 GPT glutamic--pyruvic transaminase gene PW:0002145 argininosuccinic aciduria pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00003 18416032 GPT glutamic--pyruvic transaminase gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00136 18416032 GPT glutamic--pyruvic transaminase gene PW:0002220 carbamoyl phosphate synthetase I deficiency pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00002 18416032 GPT glutamic--pyruvic transaminase gene PW:0002290 hyperargininemia pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00357 18416032 GPT glutamic--pyruvic transaminase gene PW:0002548 lactic acidosis pathway ISO RGD:734191 W RGD:9068941 20211008 SMPDB SMP:00313 18416087 PARP8 poly(ADP-ribose) polymerase family member 8 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1350347 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18416398 ATG9B autophagy related 9B gene PW:0000278 autophagy pathway ISO RGD:1352218 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18416479 RHOQ ras homolog family member Q gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:1345983 W RGD:9068941 20211008 RGD PMID:24613967|REF_RGD_ID:10053654 18416479 RHOQ ras homolog family member Q gene PW:0000143 insulin signaling pathway ISO RGD:1345983 W RGD:9068941 20211008 PID PID:200014 18416479 RHOQ ras homolog family member Q gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1345983 W RGD:9068941 20211008 PID PID:200196 18416479 RHOQ ras homolog family member Q gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1345983 W RGD:9068941 20211008 RGD PMID:24613967|REF_RGD_ID:10053654 18416650 MDN1 midasin AAA ATPase 1 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1314985 W RGD:9068941 20211008 RGD PMID:21763358|REF_RGD_ID:10002739 18416847 PTGDR prostaglandin D2 receptor gene PW:0000565 eicosanoid signaling pathway ISO RGD:1349248 W RGD:9068941 20211008 PID PID:200082 18416847 PTGDR prostaglandin D2 receptor gene PW:0001530 prostaglandin D2 signaling pathway ISO RGD:1349248 W RGD:9068941 20211008 SMPDB SMP:00343 18417015 UBE2G1 ubiquitin conjugating enzyme E2 G1 gene PW:0000015 Alzheimer's disease pathway ISO RGD:620392 W RGD:9068941 20211008 RGD PMID:11020223|REF_RGD_ID:1302873 18417015 UBE2G1 ubiquitin conjugating enzyme E2 G1 gene PW:0000144 ubiquitin/proteasome degradation pathway ISO RGD:620392 W RGD:9068941 20211008 RGD PMID:10329663|REF_RGD_ID:634475 18417015 UBE2G1 ubiquitin conjugating enzyme E2 G1 gene PW:0000294 altered ubiquitin/proteasome degradation pathway ISO RGD:620392 W RGD:9068941 20211008 RGD PMID:11020223|REF_RGD_ID:1302873 18417052 SMARCA1 SNF2 related chromatin remodeling ATPase 1 gene PW:0001407 ISWI family mediated chromatin remodeling pathway ISO RGD:1350342 W RGD:9068941 20211008 RGD PMID:21358755|REF_RGD_ID:9495920 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00075 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00096 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00086 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001524 paracetamol drug pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00710 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00083 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001665 antipyrine drug pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00692 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00116 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00704 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00706 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00094 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00077 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00120 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00114 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00106 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00109 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00098 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00085 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00084 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00289 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00093 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00696 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00104 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00104 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00700 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00709 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00708 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00353 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00705 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00697 18417228 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:1319774 W RGD:9068941 20211008 SMPDB SMP:00698 18417299 ARNT aryl hydrocarbon receptor nuclear translocator gene PW:0000360 hypoxia inducible factor pathway ISO RGD:732739 W RGD:9068941 20211008 PID PID:200036|PID:200202 18417299 ARNT aryl hydrocarbon receptor nuclear translocator gene PW:0000360 hypoxia inducible factor pathway ISO RGD:732739 W RGD:9068941 20211008 RGD PMID:22169972|REF_RGD_ID:6483352 18417299 ARNT aryl hydrocarbon receptor nuclear translocator gene PW:0000370 aryl hydrocarbon receptor signaling pathway ISO RGD:10189 W RGD:9068941 20211008 RGD PMID:1317062|REF_RGD_ID:41410437 18417300 PSEN2 presenilin 2 gene PW:0000015 Alzheimer's disease pathway ISO RGD:733569 W RGD:9068941 20211008 RGD DNA:missense mutation:cds:p.N141I (human) PMID:10976645|REF_RGD_ID:9743900 18417300 PSEN2 presenilin 2 gene PW:0000204 Notch signaling pathway ISO RGD:733569 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18417300 PSEN2 presenilin 2 gene PW:0000341 altered Notch signaling pathway involving the macromolecules modifying the main players ISO RGD:733569 W RGD:9068941 20211008 RGD C. elegans transgenics expressing wild-type and mutant PSEN2 PMID:16474849|REF_RGD_ID:2302525 18417328 HIRA histone cell cycle regulator gene PW:0001338 histone modification pathway ISO RGD:1346310 W RGD:9068941 20211008 RGD PMID:23288364|REF_RGD_ID:9068945 18417554 HDAC5 histone deacetylase 5 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:1604649 W RGD:9068941 20211008 RGD PMID:21255680|REF_RGD_ID:7241019 18417554 HDAC5 histone deacetylase 5 gene PW:0001338 histone modification pathway ISO RGD:1604649 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18417692 IL23R interleukin 23 receptor gene PW:0000915 interleukin-23 signaling pathway ISO RGD:1351657 W RGD:9068941 20211008 PID PID:200154 18417715 MIPEP mitochondrial intermediate peptidase gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1344343 W RGD:9068941 20211008 RGD PMID:22172993|REF_RGD_ID:10412669 18417738 MS4A2 membrane spanning 4-domains A2 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:1350065 W RGD:9068941 20211008 SMPDB SMP:00358 18417875 PVALB parvalbumin gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:735961 W RGD:9068941 20211008 RGD PMID:20943758|REF_RGD_ID:7204685 18418115 MAOB monoamine oxidase B gene PW:0000018 Parkinson's disease pathway ISO RGD:732580 W RGD:9068941 20211008 RGD PMID:9129714|REF_RGD_ID:1358484 18418115 MAOB monoamine oxidase B gene PW:0002117 citalopram pharmacokinetics pathway ISO RGD:732580 W RGD:9068941 20211008 SMPDB SMP:00627 18418115 MAOB monoamine oxidase B gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:732580 W RGD:9068941 20211008 SMPDB SMP:00424 18418263 KMT2A lysine methyltransferase 2A gene PW:0001338 histone modification pathway ISO RGD:1347719 W RGD:9068941 20211008 RGD PMID:22663077|PMID:23200123|REF_RGD_ID:7242632|REF_RGD_ID:9479053 18418263 KMT2A lysine methyltransferase 2A gene PW:0001340 DNA modification pathway ISO RGD:1347719 W RGD:9068941 20211008 RGD PMID:23697932|REF_RGD_ID:9479164 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0000141 retinol metabolic pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00074 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1321409 W RGD:9068941 20211008 PID PID:200146 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00648 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00600 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00433 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00622 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00406 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00590 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00086 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00640 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00336 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00327 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00601 18418320 HSP90B1 heat shock protein 90 beta family member 1 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:1321409 W RGD:9068941 20211008 SMPDB SMP:00442 18418603 SF3B1 splicing factor 3b subunit 1 gene PW:0001073 spliceosome pathway ISO RGD:1346641 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18418830 HPSE heparanase gene PW:0000659 syndecan signaling pathway ISO RGD:736250 W RGD:9068941 20211008 PID PID:200156 18418865 CCND2 cyclin D2 gene PW:0000088 G1/S transition pathway ISO RGD:730903 W RGD:9068941 20211008 RGD PMID:10919634|REF_RGD_ID:8694143 18418913 TCF7L2 transcription factor 7 like 2 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1317787 W RGD:9068941 20211008 RGD PMID:10528152|REF_RGD_ID:2301908 18418913 TCF7L2 transcription factor 7 like 2 gene PW:0000599 altered Wnt signaling, canonical pathway ISO RGD:1317786 W RGD:9068941 20211008 RGD PMID:18772397|REF_RGD_ID:5490966 18418913 TCF7L2 transcription factor 7 like 2 gene PW:0000626 pancreatic cancer pathway ISO RGD:1317786 W RGD:9068941 20211008 RGD PMID:18772397|REF_RGD_ID:5490966 18418932 IL10 interleukin 10 gene PW:0000515 Interleukin-10 signaling pathway ISO RGD:2886 W RGD:9068941 20211008 RGD PMID:19428551|REF_RGD_ID:2311043 18418932 IL10 interleukin 10 gene PW:0000515 Interleukin-10 signaling pathway ISO RGD:735591 W RGD:9068941 20211008 RGD PMID:15032600|PMID:21115385|REF_RGD_ID:1580494|REF_RGD_ID:5688379 18418932 IL10 interleukin 10 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:735591 W RGD:9068941 20211008 PID PID:200022 18419149 FLNC filamin C gene PW:0000286 integrin mediated signaling pathway ISO RGD:1558082 W RGD:9068941 20211008 RGD PMID:23719537|REF_RGD_ID:7364738 18419302 UVRAG UV radiation resistance associated gene PW:0000278 autophagy pathway ISO RGD:1317170 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18419597 SF1 splicing factor 1 gene PW:0001073 spliceosome pathway ISO RGD:1346504 W RGD:9068941 20211008 RGD PMID:19239890|REF_RGD_ID:9686089 18419638 NF1 neurofibromin 1 gene PW:0000659 syndecan signaling pathway ISO RGD:737471 W RGD:9068941 20211008 PID PID:200192 18419638 NF1 neurofibromin 1 gene PW:0000958 forkhead class A signaling pathway ISO RGD:737471 W RGD:9068941 20211008 PID PID:200087 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00133 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00132 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00134 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001880 iminoglycinuria pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00193 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00105 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0001977 Hartnup disease pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00189 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00100 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00115 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00097 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00122 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00088 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00078 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00090 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002214 cystinuria pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00723 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00118 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00135 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00121 18419741 SLC12A3 solute carrier family 12 member 3 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:733325 W RGD:9068941 20211008 SMPDB SMP:00108 18419805 RPA4 replication protein A4 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1350001 W RGD:9068941 20211008 RGD PMID:19154342|REF_RGD_ID:7246926 18419805 RPA4 replication protein A4 gene PW:0000662 mismatch repair pathway ISO RGD:1350001 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18420054 PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:737169 W RGD:9068941 20211008 RGD PMID:20801214|REF_RGD_ID:7794756 18420054 PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:631363 W RGD:9068941 20211008 RGD PMID:18454172|REF_RGD_ID:7241020 18420054 PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:737169 W RGD:9068941 20211008 RGD PMID:18454172|REF_RGD_ID:7241020 18420262 DNMBP dynamin binding protein gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:1349665 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18420297 PDE11A phosphodiesterase 11A gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:737612 W RGD:9068941 20211008 RGD PMID:17376027|REF_RGD_ID:2312479 18420397 TBK1 TANK binding kinase 1 gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1313752 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18420498 PAM16 presequence translocase associated motor 16 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1603048 W RGD:9068941 20211008 RGD PMID:25542066|REF_RGD_ID:10412659 18420855 NASP nuclear autoantigenic sperm protein gene PW:0001338 histone modification pathway ISO RGD:1605124 W RGD:9068941 20211008 RGD PMID:23288364|REF_RGD_ID:9068945 18420939 GJA5 gap junction protein alpha 5 gene PW:0000334 connexin signaling pathway ISO RGD:736164 W RGD:9068941 20211008 RGD PMID:15381756|REF_RGD_ID:1580398 18420959 SF3A3 splicing factor 3a subunit 3 gene PW:0001073 spliceosome pathway ISO RGD:1318668 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0000050 arginine and proline metabolic pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00020 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0001807 gyrate atrophy pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00363 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0001931 hyperprolinemia type I pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00361 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0001932 hyperprolinemia type II pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00360 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0002181 prolidase deficiency pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00207 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0002359 AGAT deficiency pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18421012 EPRS1 glutamyl-prolyl-tRNA synthetase 1 gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:1322145 W RGD:9068941 20211008 SMPDB SMP:00506 18421087 IL3RA interleukin 3 receptor subunit alpha gene PW:0000968 interleukin-3 signaling pathway ISO RGD:1348134 W RGD:9068941 20211008 PID PID:200145 18421106 LOC103221104 cystathionine beta-synthase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00033 18421106 LOC103221104 cystathionine beta-synthase gene PW:0000133 selenoamino acid metabolic pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00029 18421106 LOC103221104 cystathionine beta-synthase gene PW:0000400 transsulfuration pathway of homocysteine metabolism ISO RGD:737316 W RGD:9068941 20211008 RGD PMID:20162368|REF_RGD_ID:7242427 18421106 LOC103221104 cystathionine beta-synthase gene PW:0000400 transsulfuration pathway of homocysteine metabolism ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00455 18421106 LOC103221104 cystathionine beta-synthase gene PW:0001670 sarcosinemia pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00244 18421106 LOC103221104 cystathionine beta-synthase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18421106 LOC103221104 cystathionine beta-synthase gene PW:0001841 homocystinuria pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00177|SMP:00515 18421106 LOC103221104 cystathionine beta-synthase gene PW:0001868 hypermethioninemia pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00221 18421106 LOC103221104 cystathionine beta-synthase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18421106 LOC103221104 cystathionine beta-synthase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00179 18421106 LOC103221104 cystathionine beta-synthase gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00222 18421106 LOC103221104 cystathionine beta-synthase gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00340 18421106 LOC103221104 cystathionine beta-synthase gene PW:0002471 hypermethioninemia pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00341 18421106 LOC103221104 cystathionine beta-synthase gene PW:0002561 cystathioninuria pathway ISO RGD:737316 W RGD:9068941 20211008 SMPDB SMP:00514 18421133 LRPPRC leucine rich pentatricopeptide repeat containing gene PW:0001626 CRM1 export pathway ISO RGD:1315270 W RGD:9068941 20211008 RGD PMID:23583578|REF_RGD_ID:9743967 18421465 BOK BCL2 family apoptosis regulator BOK gene PW:0000104 intrinsic apoptotic pathway ISO RGD:70984 W RGD:9068941 20211008 RGD PMID:9356461|REF_RGD_ID:70678 18421465 BOK BCL2 family apoptosis regulator BOK gene PW:0000104 intrinsic apoptotic pathway ISO RGD:737138 W RGD:9068941 20211008 RGD PMID:17322918|REF_RGD_ID:2313975 18421670 LPP LIM domain containing preferred translocation partner in lipoma gene PW:0000992 E-cadherin signaling pathway ISO RGD:1321494 W RGD:9068941 20211008 PID PID:200182 18421695 GOSR2 golgi SNAP receptor complex member 2 gene PW:0000387 Arf family mediated signaling pathway ISO RGD:731739 W RGD:9068941 20211008 PID PID:200195 18421847 ADORA2B adenosine A2b receptor gene PW:0000998 adenosine signaling pathway ISO RGD:731019 W RGD:9068941 20211008 SMPDB SMP:00321 18421930 SUOX sulfite oxidase gene PW:0001647 sulfite oxidase deficiency pathway ISO RGD:733312 W RGD:9068941 20211008 SMPDB SMP:00532 18421980 GSTP1 glutathione S-transferase pi 1 gene PW:0000373 glutathione conjugation pathway ISO RGD:2758 W RGD:9068941 20211008 RGD PMID:11018474|PMID:15110098|REF_RGD_ID:1357965|REF_RGD_ID:1641942 18421980 GSTP1 glutathione S-transferase pi 1 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:732257 W RGD:9068941 20211008 SMPDB SMP:00640 18421994 ZBTB16 zinc finger and BTB domain containing 16 gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:1352454 W RGD:9068941 20211008 RGD PMID:20889352|REF_RGD_ID:5133679 18422023 NCK2 NCK adaptor protein 2 gene PW:0000143 insulin signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200014 18422023 NCK2 NCK adaptor protein 2 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200101 18422023 NCK2 NCK adaptor protein 2 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200100 18422023 NCK2 NCK adaptor protein 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200188 18422023 NCK2 NCK adaptor protein 2 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 RGD PMID:16493410|REF_RGD_ID:2300344 18422023 NCK2 NCK adaptor protein 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200149 18422023 NCK2 NCK adaptor protein 2 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200204 18422023 NCK2 NCK adaptor protein 2 gene PW:0000388 Reelin signaling pathway ISO RGD:1314306 W RGD:9068941 20211008 PID PID:200062 18422035 LTA4H leukotriene A4 hydrolase gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00075 18422035 LTA4H leukotriene A4 hydrolase gene PW:0000462 lipoxygenase mediated pathway of arachidonic acid metabolism ISO RGD:1322731 W RGD:9068941 20211008 RGD PMID:17517102|REF_RGD_ID:2313910 18422035 LTA4H leukotriene A4 hydrolase gene PW:0000464 leukotriene metabolic pathway ISO RGD:1322731 W RGD:9068941 20211008 RGD PMID:17517102|REF_RGD_ID:2313910 18422035 LTA4H leukotriene A4 hydrolase gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00096 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00086 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001524 paracetamol drug pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00710 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00083 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001665 antipyrine drug pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00692 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00116 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00704 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00706 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00094 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00077 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00120 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00114 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00106 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00109 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00098 18422035 LTA4H leukotriene A4 hydrolase gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00085 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00084 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00289 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00093 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00696 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00104 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00104 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00700 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00709 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00708 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00353 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00705 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00697 18422035 LTA4H leukotriene A4 hydrolase gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:1322731 W RGD:9068941 20211008 SMPDB SMP:00698 18422069 GRK1 G protein-coupled receptor kinase 1 gene PW:0000962 visual phototransduction pathway ISO RGD:1345543 W RGD:9068941 20211008 RGD PMID:21903131|REF_RGD_ID:6893555 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:619845 W RGD:9068941 20211008 RGD PMID:20445128|REF_RGD_ID:4892084 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:619845 W RGD:9068941 20211008 RGD PMID:20445128|REF_RGD_ID:4892084 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:735664 W RGD:9068941 20211008 RGD PMID:19767412|REF_RGD_ID:5128698 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0000507 estrogen signaling pathway ISO RGD:619845 W RGD:9068941 20211008 RGD PMID:20445128|REF_RGD_ID:4892084 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0000507 estrogen signaling pathway ISO RGD:735664 W RGD:9068941 20211008 RGD PMID:19274700|PMID:19767412|REF_RGD_ID:4892064|REF_RGD_ID:5128698 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0000854 serotonin signaling pathway ISO RGD:619845 W RGD:9068941 20211008 RGD PMID:19095043|REF_RGD_ID:39939084 18422123 GPER1 G protein-coupled estrogen receptor 1 gene PW:0001511 bisphenol A response pathway ISO RGD:735664 W RGD:9068941 20211008 RGD PMID:22927406|PMID:24382480|REF_RGD_ID:8547944|REF_RGD_ID:8548497 18422132 ACSL3 acyl-CoA synthetase long chain family member 3 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1602231 W RGD:9068941 20211008 RGD PMID:17762044|REF_RGD_ID:2317576 18422151 HGS hepatocyte growth factor-regulated tyrosine kinase substrate gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:733649 W RGD:9068941 20211008 PID PID:200188 18422151 HGS hepatocyte growth factor-regulated tyrosine kinase substrate gene PW:0000278 autophagy pathway ISO RGD:733649 W RGD:9068941 20211008 RGD PMID:19535733|REF_RGD_ID:4892619 18422151 HGS hepatocyte growth factor-regulated tyrosine kinase substrate gene PW:0000278 autophagy pathway ISO RGD:733650 W RGD:9068941 20211008 RGD PMID:19535733|REF_RGD_ID:4892619 18422338 PPP1R3D protein phosphatase 1 regulatory subunit 3D gene PW:0000532 glycogen biosynthetic pathway ISO RGD:1586306 W RGD:9068941 20211008 RGD PMID:11716774|REF_RGD_ID:2306167 18422338 PPP1R3D protein phosphatase 1 regulatory subunit 3D gene PW:0000534 glycogen degradation pathway ISO RGD:1586306 W RGD:9068941 20211008 RGD PMID:11716774|REF_RGD_ID:2306167 18422338 PPP1R3D protein phosphatase 1 regulatory subunit 3D gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1315049 W RGD:9068941 20211008 RGD PMID:21782450|REF_RGD_ID:7794757 18422343 RPP38 ribonuclease P/MRP subunit p38 gene PW:0001573 tRNA maturation pathway ISO RGD:1316690 W RGD:9068941 20211008 RGD PMID:19931535|REF_RGD_ID:9685326 18422455 CYP4B1 cytochrome P450 family 4 subfamily B member 1 gene PW:0000375 phase I biotransformation pathway via cytochrome P450 ISO RGD:2480 W RGD:9068941 20211008 RGD PMID:8248926|PMID:9310344|REF_RGD_ID:1626415|REF_RGD_ID:1626420 18422476 KDM3A lysine demethylase 3A gene PW:0001338 histone modification pathway ISO RGD:1346048 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18422727 TSEN54 tRNA splicing endonuclease subunit 54 gene PW:0001573 tRNA maturation pathway ISO RGD:1602635 W RGD:9068941 20211008 RGD PMID:25071838|REF_RGD_ID:9685342 18422916 PTN pleiotrophin gene PW:0000659 syndecan signaling pathway ISO RGD:736479 W RGD:9068941 20211008 PID PID:200198 18423200 UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 gene PW:0000101 translation pathway ISO RGD:68482 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18423200 UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 gene PW:0001066 ribosome biogenesis pathway ISO RGD:68482 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18423303 PLCD1 phospholipase C delta 1 gene PW:0000125 G protein mediated signaling pathway ISO RGD:3346 W RGD:9068941 20211008 RGD PMID:8663582|REF_RGD_ID:2301018 18423334 PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial gene PW:0000641 gluconeogenesis pathway ISO RGD:1311112 W RGD:9068941 20211008 RGD PMID:11440903|PMID:2966075|PMID:4353083|PMID:6049928|REF_RGD_ID:2302802|REF_RGD_ID:2302851|REF_RGD_ID:2302970|REF_RGD_ID:2302971 18423334 PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial gene PW:0000641 gluconeogenesis pathway ISO RGD:1322394 W RGD:9068941 20211008 RGD PMID:18613815|REF_RGD_ID:2302809 18423358 MSH3 mutS homolog 3 gene PW:0000662 mismatch repair pathway ISO RGD:1353031 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18423451 POLE4 DNA polymerase epsilon 4, accessory subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1317190 W RGD:9068941 20211008 RGD PMID:12806123|REF_RGD_ID:7246936 18423475 IGF2R insulin like growth factor 2 receptor gene PW:0000492 renin-angiotensin cascade pathway ISO RGD:2871 W RGD:9068941 20211008 RGD PMID:11247783|PMID:16672920|REF_RGD_ID:1581738|REF_RGD_ID:1581739 18423475 IGF2R insulin like growth factor 2 receptor gene PW:0000492 renin-angiotensin cascade pathway ISO RGD:732660 W RGD:9068941 20211008 RGD PMID:16672920|REF_RGD_ID:1581739 18423553 SLCO4C1 solute carrier organic anion transporter family member 4C1 gene PW:0000383 multispecific organic anion transporter mediated transport pathway ISO RGD:1303048 W RGD:9068941 20211008 RGD PMID:14993604|REF_RGD_ID:1303977 18423590 VDR vitamin D receptor gene PW:0000720 altered p53 signaling pathway ISO RGD:619561 W RGD:9068941 20211008 RGD PMID:22713868|REF_RGD_ID:8663430 18423697 OPLAH 5-oxoprolinase, ATP-hydrolysing gene PW:0000134 glutathione metabolic pathway ISO RGD:733077 W RGD:9068941 20211008 SMPDB SMP:00015 18423697 OPLAH 5-oxoprolinase, ATP-hydrolysing gene PW:0002019 glutathione synthase deficiency pathway ISO RGD:733077 W RGD:9068941 20211008 SMPDB SMP:00143|SMP:00337 18423697 OPLAH 5-oxoprolinase, ATP-hydrolysing gene PW:0002562 glutathionuria disease pathway ISO RGD:733077 W RGD:9068941 20211008 SMPDB SMP:00501 18423763 TAF8 TATA-box binding protein associated factor 8 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1318181 W RGD:9068941 20211008 RGD PMID:23146842|REF_RGD_ID:9681723 18423796 RNF111 ring finger protein 111 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1320805 W RGD:9068941 20211008 PID PID:200227 18423871 NHERF2 NHERF family PDZ scaffold protein 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:733001 W RGD:9068941 20211008 PID PID:200149 18423871 NHERF2 NHERF family PDZ scaffold protein 2 gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:733001 W RGD:9068941 20211008 RGD PMID:21777186|REF_RGD_ID:7207465 18423930 DVL2 dishevelled segment polarity protein 2 gene PW:0000008 Wnt signaling pathway ISO RGD:1320220 W RGD:9068941 20211008 RGD 18423930 DVL2 dishevelled segment polarity protein 2 gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1320220 W RGD:9068941 20211008 RGD PMID:17226800|REF_RGD_ID:2293492 18423930 DVL2 dishevelled segment polarity protein 2 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1320219 W RGD:9068941 20211008 PID PID:200077 18423930 DVL2 dishevelled segment polarity protein 2 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1320219 W RGD:9068941 20211008 PID PID:200020 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:735459 W RGD:9068941 20211008 RGD PMID:16876788|REF_RGD_ID:2316857 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00023 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0000728 statin pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0001586 Wolman disease pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00389 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0001812 mevalonic aciduria pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00112 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0001933 hypercholesterolemia pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00209 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00079 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002106 desmosterolosis pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00386 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00095 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00117 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00107 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00508 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00387 18424294 IDI1 isopentenyl-diphosphate delta isomerase 1 gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:735459 W RGD:9068941 20211008 SMPDB SMP:00388 18424458 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 gene PW:0000039 bile acid biosynthetic pathway ISO RGD:734010 W RGD:9068941 20211008 SMPDB SMP:00035 18424458 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 gene PW:0001415 Zellweger syndrome pathway ISO RGD:734010 W RGD:9068941 20211008 SMPDB SMP:00316 18424458 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:734010 W RGD:9068941 20211008 SMPDB SMP:00315 18424458 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 gene PW:0002302 familial hypercholanemia pathway ISO RGD:734010 W RGD:9068941 20211008 SMPDB SMP:00317 18424458 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:734010 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18424658 AADAT aminoadipate aminotransferase gene PW:0000054 tryptophan metabolic pathway ISO RGD:1606004 W RGD:9068941 20211008 SMPDB SMP:00063 18424658 AADAT aminoadipate aminotransferase gene PW:0000054 tryptophan metabolic pathway ISO RGD:2948 W RGD:9068941 20211008 RGD PMID:3400092|PMID:6466295|REF_RGD_ID:2290312|REF_RGD_ID:2290313 18424658 AADAT aminoadipate aminotransferase gene PW:0000073 lysine degradation pathway ISO RGD:1606004 W RGD:9068941 20211008 SMPDB SMP:00037 18424658 AADAT aminoadipate aminotransferase gene PW:0001282 kynurenine metabolic pathway ISO RGD:1606004 W RGD:9068941 20211008 RGD PMID:19826765|REF_RGD_ID:11081066 18424658 AADAT aminoadipate aminotransferase gene PW:0001282 kynurenine metabolic pathway ISO RGD:2948 W RGD:9068941 20211008 RGD PMID:19826765|REF_RGD_ID:11081066 18424658 AADAT aminoadipate aminotransferase gene PW:0001282 kynurenine metabolic pathway ISO RGD:735758 W RGD:9068941 20211008 RGD PMID:19826765|REF_RGD_ID:11081066 18424658 AADAT aminoadipate aminotransferase gene PW:0001703 saccharopinuria pathway ISO RGD:1606004 W RGD:9068941 20211008 SMPDB SMP:00239|SMP:00528 18424658 AADAT aminoadipate aminotransferase gene PW:0001936 hyperlysinemia pathway ISO RGD:1606004 W RGD:9068941 20211008 SMPDB SMP:00527 18424658 AADAT aminoadipate aminotransferase gene PW:0002204 2-aminoadipic 2-oxoadipic aciduria pathway ISO RGD:1606004 W RGD:9068941 20211008 SMPDB SMP:00719 18424658 AADAT aminoadipate aminotransferase gene PW:0002306 glutaric aciduria type I pathway ISO RGD:1606004 W RGD:9068941 20211008 SMPDB SMP:00186 18424755 ACTR1A actin related protein 1A gene PW:0002061 mitochondria transport pathway ISO RGD:1315973 W RGD:9068941 20211008 RGD PMID:15473859|REF_RGD_ID:10402155 18424920 SIRT2 sirtuin 2 gene PW:0001338 histone modification pathway ISO RGD:733995 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18424920 SIRT2 sirtuin 2 gene PW:0002584 Sirtuin mediated pathway ISO RGD:733995 W RGD:9068941 20211008 RGD PMID:26785480|REF_RGD_ID:11100032 18425134 HNRNPK heterogeneous nuclear ribonucleoprotein K gene PW:0001073 spliceosome pathway ISO RGD:733485 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18425182 H2AFY core histone macro-H2A.1 gene PW:0001338 histone modification pathway ISO RGD:731902 W RGD:9068941 20211008 RGD PMID:24696452|REF_RGD_ID:9074213 18425381 TALDO1 transaldolase 1 gene PW:0000045 pentose phosphate pathway ISO RGD:620674 W RGD:9068941 20211008 RGD PMID:2843500|REF_RGD_ID:1599574 18425381 TALDO1 transaldolase 1 gene PW:0000045 pentose phosphate pathway ISO RGD:733188 W RGD:9068941 20211008 SMPDB SMP:00031 18425381 TALDO1 transaldolase 1 gene PW:0000574 pentose phosphate pathway - non-oxidative phase ISO RGD:620674 W RGD:9068941 20211008 RGD PMID:12721358|PMID:8477719|REF_RGD_ID:1641803|REF_RGD_ID:1641814 18425381 TALDO1 transaldolase 1 gene PW:0001629 transaldolase deficiency pathway ISO RGD:733188 W RGD:9068941 20211008 SMPDB SMP:00520 18425381 TALDO1 transaldolase 1 gene PW:0001704 ribose 5-phosphate isomerase deficiency pathway ISO RGD:733188 W RGD:9068941 20211008 SMPDB SMP:00519 18425434 NNMT nicotinamide N-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1320034 W RGD:9068941 20211008 RGD PMID:15922112|REF_RGD_ID:1359084 18425434 NNMT nicotinamide N-methyltransferase gene PW:0000398 homocysteine metabolic pathway ISO RGD:1320034 W RGD:9068941 20211008 RGD PMID:15922112|REF_RGD_ID:1359084 18425434 NNMT nicotinamide N-methyltransferase gene PW:0001010 niacin metabolic pathway ISO RGD:1320034 W RGD:9068941 20211008 SMPDB SMP:00048 18425452 YY1 YY1 transcription factor gene PW:0000180 mTOR signaling pathway ISO RGD:736235 W RGD:9068941 20211008 PID PID:200096 18425452 YY1 YY1 transcription factor gene PW:0000204 Notch signaling pathway ISO RGD:736235 W RGD:9068941 20211008 PID PID:200015 18425452 YY1 YY1 transcription factor gene PW:0000718 p53 signaling pathway ISO RGD:736235 W RGD:9068941 20211008 PID PID:200206 18425452 YY1 YY1 transcription factor gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:736235 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18425496 CPSF6 cleavage and polyadenylation specific factor 6 gene PW:0001332 RNA polymerase II transcription termination pathway ISO RGD:1312196 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18425496 CPSF6 cleavage and polyadenylation specific factor 6 gene PW:0001579 3'-end pre-mRNA processing pathway ISO RGD:1312196 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18425584 EXOC5 exocyst complex component 5 gene PW:0000143 insulin signaling pathway ISO RGD:731494 W RGD:9068941 20211008 PID PID:200014 18425611 PSAT1 phosphoserine aminotransferase 1 gene PW:0001670 sarcosinemia pathway ISO RGD:1607031 W RGD:9068941 20211008 SMPDB SMP:00244 18425611 PSAT1 phosphoserine aminotransferase 1 gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1607031 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18425611 PSAT1 phosphoserine aminotransferase 1 gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1607031 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18425611 PSAT1 phosphoserine aminotransferase 1 gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1607031 W RGD:9068941 20211008 SMPDB SMP:00179 18425835 SNAPC4 small nuclear RNA activating complex polypeptide 4 gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1319171 W RGD:9068941 20211008 RGD PMID:23031840|REF_RGD_ID:9588284 18425903 HTT huntingtin gene PW:0000017 Huntington's disease pathway ISO RGD:68472 W RGD:9068941 20211008 RGD PMID:21163446|PMID:26938440|REF_RGD_ID:11062152|REF_RGD_ID:11062153 18426003 TADA3 transcriptional adaptor 3 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1314884 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18426210 GNB1 G protein subunit beta 1 gene PW:0000122 Hedgehog signaling pathway ISO RGD:732785 W RGD:9068941 20211008 PID PID:200172 18426210 GNB1 G protein subunit beta 1 gene PW:0000230 G protein mediated signaling pathway via Galpha12/Galpha13 family ISO RGD:2718 W RGD:9068941 20211008 RGD PMID:9092554|REF_RGD_ID:1582440 18426210 GNB1 G protein subunit beta 1 gene PW:0000365 melanocortin system pathway ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00310 18426210 GNB1 G protein subunit beta 1 gene PW:0000565 eicosanoid signaling pathway ISO RGD:732785 W RGD:9068941 20211008 PID PID:200082 18426210 GNB1 G protein subunit beta 1 gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00322 18426210 GNB1 G protein subunit beta 1 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00308 18426210 GNB1 G protein subunit beta 1 gene PW:0000962 visual phototransduction pathway ISO RGD:732785 W RGD:9068941 20211008 RGD PMID:22074925|REF_RGD_ID:6893539 18426210 GNB1 G protein subunit beta 1 gene PW:0000998 adenosine signaling pathway ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18426210 GNB1 G protein subunit beta 1 gene PW:0001070 luteinizing hormone signaling pathway ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00338 18426210 GNB1 G protein subunit beta 1 gene PW:0001071 follicle-stimulating hormone signaling pathway ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00333 18426210 GNB1 G protein subunit beta 1 gene PW:0001091 serotonin signaling pathway via receptors engaging G alphas protein family ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00309|SMP:00311|SMP:00312 18426210 GNB1 G protein subunit beta 1 gene PW:0001530 prostaglandin D2 signaling pathway ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00343 18426210 GNB1 G protein subunit beta 1 gene PW:0001531 prostaglandin I2 signaling pathway ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00354 18426210 GNB1 G protein subunit beta 1 gene PW:0002119 histamine signaling pathway, immunological ISO RGD:732785 W RGD:9068941 20211008 SMPDB SMP:00335 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00133 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00132 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00134 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001880 iminoglycinuria pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00193 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00105 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0001977 Hartnup disease pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00189 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00100 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00115 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00097 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00122 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00088 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00078 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00090 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002214 cystinuria pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00723 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00118 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00135 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00121 18426442 SLC3A1 solute carrier family 3 member 1 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:1345624 W RGD:9068941 20211008 SMPDB SMP:00108 18426556 HK2 hexokinase 2 gene PW:0000151 starch and sucrose metabolic pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00058 18426556 HK2 hexokinase 2 gene PW:0000306 altered galactose metabolic pathway ISO RGD:2797 W RGD:9068941 20211008 RGD PMID:7622509|REF_RGD_ID:632917 18426556 HK2 hexokinase 2 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:733090 W RGD:9068941 20211008 PID PID:200202 18426556 HK2 hexokinase 2 gene PW:0000640 glycolysis pathway ISO RGD:2797 W RGD:9068941 20211008 RGD PMID:9540816|REF_RGD_ID:2302784 18426556 HK2 hexokinase 2 gene PW:0000640 glycolysis pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00040 18426556 HK2 hexokinase 2 gene PW:0000641 gluconeogenesis pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00128 18426556 HK2 hexokinase 2 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00563 18426556 HK2 hexokinase 2 gene PW:0001648 congenital sucrase-isomaltase deficiency pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00557 18426556 HK2 hexokinase 2 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18426556 HK2 hexokinase 2 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00573 18426556 HK2 hexokinase 2 gene PW:0001994 glycogen storage disease type III pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00553 18426556 HK2 hexokinase 2 gene PW:0001995 glycogen storage disease type IV pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00554 18426556 HK2 hexokinase 2 gene PW:0001996 glycogen storage disease type VI pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00555 18426556 HK2 hexokinase 2 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00531 18426556 HK2 hexokinase 2 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00562 18426556 HK2 hexokinase 2 gene PW:0002360 Fanconi syndrome pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00572 18426556 HK2 hexokinase 2 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:733090 W RGD:9068941 20211008 SMPDB SMP:00560 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:736081 W RGD:9068941 20211008 RGD PMID:11454900|REF_RGD_ID:1559318 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00671 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00431 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00413 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00402 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00686 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00687 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00691 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00408 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00399 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00422 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00426 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00415 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00425 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00423 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00424 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00684 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00393 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00401 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00404 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00688 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00416 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00397 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00409 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00410 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00411 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00412 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00394 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00681 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00395 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00398 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00400 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00677 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00673 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00407 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00675 18426972 ADRA1A adrenoceptor alpha 1A gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:736081 W RGD:9068941 20211008 SMPDB SMP:00367 18427007 ELAVL1 ELAV like RNA binding protein 1 gene PW:0001626 CRM1 export pathway ISO RGD:1318543 W RGD:9068941 20211008 RGD PMID:23583578|REF_RGD_ID:9743967 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00034 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00025 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0001156 glycerolipid metabolic pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00039 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0001454 Gaucher's disease pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00349 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0001876 plasmalogen metabolic pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00479 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0001877 plasmalogen biosynthetic pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00479 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0002018 glycerol kinase deficiency pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00187 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0002021 Krabbe disease pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00348 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0002103 Fabry disease pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00525 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0002212 D-glycericacidemia pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00529 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00347 18427364 PLPP1 phospholipid phosphatase 1 gene PW:0002557 familial lipoprotein lipase deficiency pathway ISO RGD:1344834 W RGD:9068941 20211008 SMPDB SMP:00530 18427384 SRSF3 serine and arginine rich splicing factor 3 gene PW:0001073 spliceosome pathway ISO RGD:1319459 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18427399 MOCS2 molybdenum cofactor synthesis 2 gene PW:0000427 molybdenum cofactor biosynthetic pathway ISO RGD:1347583 W RGD:9068941 20211008 RGD PMID:16784786|REF_RGD_ID:1625104 18427538 ARPC2 actin related protein 2/3 complex subunit 2 gene PW:0000159 Rab family mediated signaling pathway ISO RGD:1305848 W RGD:9068941 20211008 RGD PMID:20739464|REF_RGD_ID:10054052 18427538 ARPC2 actin related protein 2/3 complex subunit 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1314126 W RGD:9068941 20211008 PID PID:200149 18427538 ARPC2 actin related protein 2/3 complex subunit 2 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1305848 W RGD:9068941 20211008 RGD PMID:20739464|REF_RGD_ID:10054052 18427650 UCHL5 ubiquitin C-terminal hydrolase L5 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1313432 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000143 insulin signaling pathway ISO RGD:1310949 W RGD:9068941 20211008 RGD PMID:12891559|REF_RGD_ID:1299201 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000143 insulin signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200014 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000143 insulin signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 SMPDB SMP:00391 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000158 Ras family mediated signaling pathway ISO RGD:1310949 W RGD:9068941 20211008 RGD PMID:15728722|REF_RGD_ID:1581104 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000169 nerve growth factor signaling pathway ISO RGD:1310949 W RGD:9068941 20211008 RGD PMID:15728722|REF_RGD_ID:1581104 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1310949 W RGD:9068941 20211008 RGD PMID:8577724|REF_RGD_ID:1581110 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200101 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 RGD PMID:16829981|REF_RGD_ID:2317988 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200100 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200149|PID:200162 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200220 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200227 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200146 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1322140 W RGD:9068941 20221027 RGD PMID:22029668|PMID:9815779|REF_RGD_ID:155631264|REF_RGD_ID:5686834 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200098 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200019 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0000987 erythropoietin signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 PID PID:200183 18427864 SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:1322140 W RGD:9068941 20211008 SMPDB SMP:00358 18427974 MED24 mediator complex subunit 24 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1348876 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18428053 HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1317966 W RGD:9068941 20211008 PID PID:200036 18428053 HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1317966 W RGD:9068941 20211008 RGD PMID:14597660|PMID:19364912|PMID:22169972|REF_RGD_ID:1334466|REF_RGD_ID:6483352|REF_RGD_ID:6483358 18428179 MED12 mediator complex subunit 12 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1350145 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18428351 SETD1B SET domain containing 1B, histone lysine methyltransferase gene PW:0001338 histone modification pathway ISO RGD:1602124 W RGD:9068941 20211008 RGD PMID:22663077|PMID:23200123|REF_RGD_ID:7242632|REF_RGD_ID:9479053 18428469 DDIT4 DNA damage inducible transcript 4 gene PW:0000180 mTOR signaling pathway ISO RGD:1346554 W RGD:9068941 20211008 PID PID:200096 18428487 TTR transthyretin gene PW:0000958 forkhead class A signaling pathway ISO RGD:737331 W RGD:9068941 20211008 PID PID:200087 18428487 TTR transthyretin gene PW:0001004 retinoic acid metabolic pathway ISO RGD:737331 W RGD:9068941 20211008 RGD PMID:21782034|REF_RGD_ID:6484671 18428726 VEGFA vascular endothelial growth factor A gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:619991 W RGD:9068941 20220519 RGD PMID:17272396|REF_RGD_ID:152177689 18428726 VEGFA vascular endothelial growth factor A gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:619991 W RGD:9068941 20211008 RGD PMID:12181492|PMID:15785231|PMID:16160062|PMID:18614764|REF_RGD_ID:1626621|REF_RGD_ID:2301848|REF_RGD_ID:2301956|REF_RGD_ID:625593 18428726 VEGFA vascular endothelial growth factor A gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:731072 W RGD:9068941 20211008 RGD PMID:15563310|PMID:16633338|PMID:18221855|REF_RGD_ID:1334463|REF_RGD_ID:2292019|REF_RGD_ID:2298727 18428726 VEGFA vascular endothelial growth factor A gene PW:0000351 altered vascular endothelial growth factor signaling pathway involving the main players ISO RGD:731072 W RGD:9068941 20211008 RGD PMID:18221855|REF_RGD_ID:2292019 18428726 VEGFA vascular endothelial growth factor A gene PW:0000353 altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression ISO RGD:731072 W RGD:9068941 20211008 RGD PMID:18221855|REF_RGD_ID:2292019 18428726 VEGFA vascular endothelial growth factor A gene PW:0000360 hypoxia inducible factor pathway ISO RGD:731072 W RGD:9068941 20211008 PID PID:200036|PID:200202 18428726 VEGFA vascular endothelial growth factor A gene PW:0000658 glypican signaling pathway ISO RGD:731072 W RGD:9068941 20211008 PID PID:200026 18428726 VEGFA vascular endothelial growth factor A gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:731072 W RGD:9068941 20211008 PID PID:200046|PID:200085 18428726 VEGFA vascular endothelial growth factor A gene PW:0001122 bevacizumab pharmacodynamics pathway ISO RGD:731072 W RGD:9068941 20211008 SMPDB SMP:00420 18428962 CALM2 calmodulin 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:736342 W RGD:9068941 20211008 PID PID:200018 18428962 CALM2 calmodulin 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:736342 W RGD:9068941 20211008 PID PID:200188 18428962 CALM2 calmodulin 2 gene PW:0000534 glycogen degradation pathway ISO RGD:736342 W RGD:9068941 20211008 RGD PMID:10487978|REF_RGD_ID:2305981 18428962 CALM2 calmodulin 2 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:736342 W RGD:9068941 20211008 RGD PMID:16054095|REF_RGD_ID:2311420 18428962 CALM2 calmodulin 2 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:736342 W RGD:9068941 20211008 PID PID:200196 18428962 CALM2 calmodulin 2 gene PW:0000896 type II interferon signaling pathway ISO RGD:736342 W RGD:9068941 20211008 PID PID:200129 18428962 CALM2 calmodulin 2 gene PW:0000993 N-cadherin signaling pathway ISO RGD:736342 W RGD:9068941 20211008 PID PID:200209 18428962 CALM2 calmodulin 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:736342 W RGD:9068941 20211008 RGD PMID:10884684|PMID:18083096|REF_RGD_ID:7204676|REF_RGD_ID:7204677 18428962 CALM2 calmodulin 2 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:736342 W RGD:9068941 20211008 RGD PMID:22717267|PMID:23091085|REF_RGD_ID:7240705|REF_RGD_ID:7240708 18428977 SRF serum response factor gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1321393 W RGD:9068941 20211008 PID PID:200149|PID:200162 18429000 LIMA1 LIM domain and actin binding 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1602328 W RGD:9068941 20211008 PID PID:200182 18429061 MAP3K12 mitogen-activated protein kinase kinase kinase 12 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:737536 W RGD:9068941 20211008 RGD PMID:17306896|REF_RGD_ID:2293875 18429092 AGT angiotensinogen gene PW:0000060 long term potentiation ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:11282364|REF_RGD_ID:1582105 18429092 AGT angiotensinogen gene PW:0000244 angiotensin II signaling pathway ISO RGD:10118 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18429092 AGT angiotensinogen gene PW:0000244 angiotensin II signaling pathway ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18429092 AGT angiotensinogen gene PW:0000244 angiotensin II signaling pathway ISO RGD:731070 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18429092 AGT angiotensinogen gene PW:0000245 angiotensin signaling pathway ISO RGD:731070 W RGD:9068941 20211008 RGD PMID:12676165|REF_RGD_ID:1566511 18429092 AGT angiotensinogen gene PW:0000299 myocardial infarction pathway ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:21167013|REF_RGD_ID:5129191 18429092 AGT angiotensinogen gene PW:0000457 angiotensin III signaling pathway ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:11295571|REF_RGD_ID:1582124 18429092 AGT angiotensinogen gene PW:0000458 angiotensin IV signaling pathway ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:11282364|REF_RGD_ID:1582105 18429092 AGT angiotensinogen gene PW:0000492 renin-angiotensin cascade pathway ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:11282364|PMID:12242043|REF_RGD_ID:1581651|REF_RGD_ID:1582105 18429092 AGT angiotensinogen gene PW:0000492 renin-angiotensin cascade pathway ISO RGD:731070 W RGD:9068941 20211008 RGD PMID:15638741|REF_RGD_ID:1581742 18429092 AGT angiotensinogen gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:10118 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18429092 AGT angiotensinogen gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18429092 AGT angiotensinogen gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:731070 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18429092 AGT angiotensinogen gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:10118 W RGD:9068941 20211008 RGD PMID:16286564|PMID:16286568|REF_RGD_ID:1582434|REF_RGD_ID:1582435 18429092 AGT angiotensinogen gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:16286564|PMID:16286568|REF_RGD_ID:1582434|REF_RGD_ID:1582435 18429092 AGT angiotensinogen gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:731070 W RGD:9068941 20211008 RGD PMID:16286564|PMID:16286568|PMID:22949090|REF_RGD_ID:1582434|REF_RGD_ID:1582435|REF_RGD_ID:7401256 18429092 AGT angiotensinogen gene PW:0000529 angiotensin (1-7) signaling pathway ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:15951342|REF_RGD_ID:1581938 18429092 AGT angiotensinogen gene PW:0000530 angiotensin III signaling pathway via AT1 receptor ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:11100981|REF_RGD_ID:1582152 18429092 AGT angiotensinogen gene PW:0000531 angiotensin III signaling pathway via AT2 receptor ISO RGD:2069 W RGD:9068941 20211008 RGD PMID:16380540|REF_RGD_ID:1582118 18429092 AGT angiotensinogen gene PW:0001464 losartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00162 18429092 AGT angiotensinogen gene PW:0001689 valsartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00165 18429092 AGT angiotensinogen gene PW:0001709 enalapril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00148 18429092 AGT angiotensinogen gene PW:0001712 ramipril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00154 18429092 AGT angiotensinogen gene PW:0001715 quinapril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00153 18429092 AGT angiotensinogen gene PW:0001718 perindopril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00152 18429092 AGT angiotensinogen gene PW:0001720 lisinopril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00150 18429092 AGT angiotensinogen gene PW:0001724 benazepril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00145 18429092 AGT angiotensinogen gene PW:0001727 trandolapril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00157 18429092 AGT angiotensinogen gene PW:0001730 cilazapril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00147 18429092 AGT angiotensinogen gene PW:0001798 telmisartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00164 18429092 AGT angiotensinogen gene PW:0001827 spirapril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00156 18429092 AGT angiotensinogen gene PW:0001909 olmesartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00163 18429092 AGT angiotensinogen gene PW:0001984 irbesartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00161 18429092 AGT angiotensinogen gene PW:0002024 fosinopril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00149 18429092 AGT angiotensinogen gene PW:0002027 forasartsn pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00160 18429092 AGT angiotensinogen gene PW:0002060 eprosartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00159 18429092 AGT angiotensinogen gene PW:0002127 captopril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00146 18429092 AGT angiotensinogen gene PW:0002130 candesartan pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00158 18429092 AGT angiotensinogen gene PW:0002165 moexipril pharmacodynamics pathway ISO RGD:731070 W RGD:9068941 20211008 SMPDB SMP:00151 18429144 DDX56 DEAD-box helicase 56 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1349129 W RGD:9068941 20211008 RGD PMID:22922795|REF_RGD_ID:10002738 18429375 CTNNA1 catenin alpha 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1348842 W RGD:9068941 20211008 PID PID:200188 18429375 CTNNA1 catenin alpha 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1348842 W RGD:9068941 20211008 PID PID:200124|PID:200147|PID:200182 18429375 CTNNA1 catenin alpha 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:1348842 W RGD:9068941 20211008 PID PID:200209 18429478 JMJD1C jumonji domain containing 1C gene PW:0001338 histone modification pathway ISO RGD:1320591 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18429578 PSPH phosphoserine phosphatase gene PW:0001670 sarcosinemia pathway ISO RGD:1318726 W RGD:9068941 20211008 SMPDB SMP:00244 18429578 PSPH phosphoserine phosphatase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1318726 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18429578 PSPH phosphoserine phosphatase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1318726 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18429578 PSPH phosphoserine phosphatase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1318726 W RGD:9068941 20211008 SMPDB SMP:00179 18429590 CALM3 calmodulin 3 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:737387 W RGD:9068941 20211008 PID PID:200018 18429590 CALM3 calmodulin 3 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:737387 W RGD:9068941 20211008 PID PID:200188 18429590 CALM3 calmodulin 3 gene PW:0000534 glycogen degradation pathway ISO RGD:737387 W RGD:9068941 20211008 RGD PMID:10487978|REF_RGD_ID:2305981 18429590 CALM3 calmodulin 3 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:737387 W RGD:9068941 20211008 RGD PMID:16054095|REF_RGD_ID:2311420 18429590 CALM3 calmodulin 3 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:737387 W RGD:9068941 20211008 PID PID:200196 18429590 CALM3 calmodulin 3 gene PW:0000896 type II interferon signaling pathway ISO RGD:737387 W RGD:9068941 20211008 PID PID:200129 18429590 CALM3 calmodulin 3 gene PW:0000993 N-cadherin signaling pathway ISO RGD:737387 W RGD:9068941 20211008 PID PID:200209 18429590 CALM3 calmodulin 3 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:737387 W RGD:9068941 20211008 RGD PMID:10884684|PMID:18083096|REF_RGD_ID:7204676|REF_RGD_ID:7204677 18429590 CALM3 calmodulin 3 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:737387 W RGD:9068941 20211008 RGD PMID:22717267|PMID:23091085|REF_RGD_ID:7240705|REF_RGD_ID:7240708 18429648 CAVIN1 caveolae associated protein 1 gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1317018 W RGD:9068941 20211008 RGD PMID:23092677|REF_RGD_ID:9588249 18429654 DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 gene PW:0002401 chaperone mediated autophagy pathway ISO RGD:1312336 W RGD:9068941 20211008 RGD PMID:25724482|REF_RGD_ID:10755685 18429684 RRAGC Ras related GTP binding C gene PW:0000180 mTOR signaling pathway ISO RGD:1323384 W RGD:9068941 20211008 PID PID:200096 18429684 RRAGC Ras related GTP binding C gene PW:0000180 mTOR signaling pathway ISO RGD:1323384 W RGD:9068941 20211008 RGD PMID:19339977|PMID:24698685|REF_RGD_ID:11535043|REF_RGD_ID:2308795 18429755 WNT8A Wnt family member 8A gene PW:0000008 Wnt signaling pathway ISO RGD:1314861 W RGD:9068941 20211008 RGD 18429755 WNT8A Wnt family member 8A gene PW:0000008 Wnt signaling pathway ISO RGD:1314862 W RGD:9068941 20211008 RGD 18429755 WNT8A Wnt family member 8A gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1314861 W RGD:9068941 20211008 RGD PMID:18765832|REF_RGD_ID:2313743 18429814 ZBTB38 zinc finger and BTB domain containing 38 gene PW:0001340 DNA modification pathway ISO RGD:1603531 W RGD:9068941 20211008 RGD PMID:23324617|REF_RGD_ID:8695954 18429854 OAT ornithine aminotransferase gene PW:0000050 arginine and proline metabolic pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00020 18429854 OAT ornithine aminotransferase gene PW:0001807 gyrate atrophy pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00363 18429854 OAT ornithine aminotransferase gene PW:0001931 hyperprolinemia type I pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00361 18429854 OAT ornithine aminotransferase gene PW:0001932 hyperprolinemia type II pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00360 18429854 OAT ornithine aminotransferase gene PW:0002181 prolidase deficiency pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00207 18429854 OAT ornithine aminotransferase gene PW:0002215 guanidinoacetate methyltransferase deficiency pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00188|SMP:00504 18429854 OAT ornithine aminotransferase gene PW:0002359 AGAT deficiency pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00362|SMP:00507 18429854 OAT ornithine aminotransferase gene PW:0002563 ornithine translocase deficiency pathway ISO RGD:1350711 W RGD:9068941 20211008 SMPDB SMP:00506 18429991 AKAP13 A-kinase anchoring protein 13 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:736118 W RGD:9068941 20211008 RGD PMID:14715913|PMID:19319965|REF_RGD_ID:2312475|REF_RGD_ID:2312477 18430095 RAP1B RAP1B, member of RAS oncogene family gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:736930 W RGD:9068941 20211008 PID PID:200149 18430095 RAP1B RAP1B, member of RAS oncogene family gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:736930 W RGD:9068941 20211008 PID PID:200052 18430095 RAP1B RAP1B, member of RAS oncogene family gene PW:0000896 type II interferon signaling pathway ISO RGD:736930 W RGD:9068941 20211008 PID PID:200129 18430095 RAP1B RAP1B, member of RAS oncogene family gene PW:0000992 E-cadherin signaling pathway ISO RGD:736930 W RGD:9068941 20211008 PID PID:200124 18430150 PAM peptidylglycine alpha-amidating monooxygenase gene PW:0000365 melanocortin system pathway ISO RGD:735807 W RGD:9068941 20211008 RGD PMID:11874690|REF_RGD_ID:1357926 18430194 AGO4 argonaute RISC component 4 gene PW:0000808 microRNA pathway ISO RGD:1312105 W RGD:9068941 20211008 RGD PMID:20484662|REF_RGD_ID:4144862 18430240 AQP5 aquaporin 5 gene PW:0000419 water transport pathway ISO RGD:70371 W RGD:9068941 20211008 RGD PMID:19096774|REF_RGD_ID:2312795 18430240 AQP5 aquaporin 5 gene PW:0000992 E-cadherin signaling pathway ISO RGD:70371 W RGD:9068941 20211008 PID PID:200182 18430293 AICDA activation induced cytidine deaminase gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1347771 W RGD:9068941 20211008 PID PID:200022 18430430 NUP37 nucleoporin 37 gene PW:0001587 mRNA nuclear export pathway ISO RGD:1317159 W RGD:9068941 20211008 RGD PMID:25184662|REF_RGD_ID:9743947 18430481 UROC1 urocanate hydratase 1 gene PW:0000051 histidine metabolic pathway ISO RGD:1347314 W RGD:9068941 20211008 SMPDB SMP:00044 18430481 UROC1 urocanate hydratase 1 gene PW:0001978 histidinemia pathway ISO RGD:1347314 W RGD:9068941 20211008 SMPDB SMP:00191 18430542 TFF1 trefoil factor 1 gene PW:0000958 forkhead class A signaling pathway ISO RGD:1344671 W RGD:9068941 20211008 PID PID:200226 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0000058 fatty acid metabolic pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00051 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00032 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:620482 W RGD:9068941 20211008 RGD PMID:11879205|REF_RGD_ID:2317624 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00480|SMP:00481|SMP:00482 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001136 fatty acid elongation pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00054 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001594 very long-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00540 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001627 trifunctional protein deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00545 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001667 short-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00235 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001668 3-hydroxyacyl-CoA dehydrogenase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00568 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001778 propionic acidemia pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00236 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00384 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001810 methylmalonic acidemia pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00200 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001869 medium chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00542 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001870 maple syrup urine disease pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00199 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001874 isovaleric acidemia pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00523 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002206 ethylmalonic encephalopathy pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00181 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00139 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00140 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002306 glutaric aciduria type I pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00185 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00138 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002574 carnitine palmitoyltransferase I deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00538 18430629 ACAA2 acetyl-CoA acyltransferase 2 gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:733990 W RGD:9068941 20211008 SMPDB SMP:00237 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0000032 pyrimidine metabolic pathway ISO RGD:621218 W RGD:9068941 20211008 RGD PMID:7626590|REF_RGD_ID:1624989 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0000032 pyrimidine metabolic pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00046 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0000077 beta-alanine metabolic pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00007 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0001603 beta-ureidopropionase deficiency pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00172 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0001605 orotic aciduria 1 pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00219 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0002095 GABA aminotransferase deficiency pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00351 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0002211 dihydropyrimidinase deficiency pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00178 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0002365 mitochondrial neurogastrointestinal encephalopathy syndrome pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00202 18430743 DPYD dihydropyrimidine dehydrogenase gene PW:0002565 carnosinemia pathway ISO RGD:731730 W RGD:9068941 20211008 SMPDB SMP:00493 18430937 RPS19 ribosomal protein S19 gene PW:0000101 translation pathway ISO RGD:68661 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18430937 RPS19 ribosomal protein S19 gene PW:0001066 ribosome biogenesis pathway ISO RGD:68661 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23439679|PMID:23636399|PMID:25346433|REF_RGD_ID:10002730|REF_RGD_ID:10002762|REF_RGD_ID:9999448|REF_RGD_ID:9999449 18430997 LOC103243033 histone H3.3A gene PW:0001338 histone modification pathway ISO RGD:733608 W RGD:9068941 20211008 RGD PMID:24614311|REF_RGD_ID:9075965 18431239 PHKG2 phosphorylase kinase catalytic subunit gamma 2 gene PW:0000534 glycogen degradation pathway ISO RGD:732798 W RGD:9068941 20211008 RGD PMID:10487978|REF_RGD_ID:2305981 18431252 EGLN1 egl-9 family hypoxia inducible factor 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:735297 W RGD:9068941 20211008 RGD PMID:14597660|REF_RGD_ID:1334466 18431252 EGLN1 egl-9 family hypoxia inducible factor 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:631375 W RGD:9068941 20211008 RGD PMID:12876291|PMID:14597660|REF_RGD_ID:1334466|REF_RGD_ID:727754 18431252 EGLN1 egl-9 family hypoxia inducible factor 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:735297 W RGD:9068941 20211008 PID PID:200036|PID:200202 18431252 EGLN1 egl-9 family hypoxia inducible factor 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:735297 W RGD:9068941 20211008 RGD PMID:19364912|PMID:20396958|REF_RGD_ID:6483358|REF_RGD_ID:6483503 18431325 FNIP2 folliculin interacting protein 2 gene PW:0000180 mTOR signaling pathway ISO RGD:2292121 W RGD:9068941 20211008 RGD PMID:27076075|REF_RGD_ID:11535042 18431371 RPS27A ribosomal protein S27a gene PW:0000101 translation pathway ISO RGD:736388 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18431371 RPS27A ribosomal protein S27a gene PW:0001066 ribosome biogenesis pathway ISO RGD:736388 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18432190 PTGES3 prostaglandin E synthase 3 gene PW:0000507 estrogen signaling pathway ISO RGD:1606321 W RGD:9068941 20211008 RGD PMID:18451092|REF_RGD_ID:4892102 18432190 PTGES3 prostaglandin E synthase 3 gene PW:0000568 aldosterone signaling pathway ISO RGD:1606321 W RGD:9068941 20211008 RGD PMID:21784126|REF_RGD_ID:7421504 18432190 PTGES3 prostaglandin E synthase 3 gene PW:0000569 cortisol signaling pathway ISO RGD:1606321 W RGD:9068941 20211008 RGD PMID:16610357|REF_RGD_ID:5144125 18432190 PTGES3 prostaglandin E synthase 3 gene PW:0001532 prostaglandin biosynthetic pathway ISO RGD:1606321 W RGD:9068941 20211008 RGD PMID:22679221|PMID:23063076|REF_RGD_ID:8552701|REF_RGD_ID:8552712 18432451 APOOL apolipoprotein O like gene PW:0001962 mitochondrial protein import pathway contributes_to ISO RGD:1351827 W RGD:9068941 20211008 RGD PMID:23109542|REF_RGD_ID:10412671 18432607 TNFRSF1B TNF receptor superfamily member 1B gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1298224 W RGD:9068941 20211008 PID PID:200102 18432607 TNFRSF1B TNF receptor superfamily member 1B gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1298224 W RGD:9068941 20211008 RGD PMID:12655295|REF_RGD_ID:2292150 18432921 CTNNB1 catenin beta 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:70487 W RGD:9068941 20211008 RGD PMID:16478782|PMID:20042609|REF_RGD_ID:1581696|REF_RGD_ID:7242068 18432921 CTNNB1 catenin beta 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:733705 W RGD:9068941 20211008 PID PID:200077 18432921 CTNNB1 catenin beta 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:733705 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18432921 CTNNB1 catenin beta 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:733705 W RGD:9068941 20211008 PID PID:200188 18432921 CTNNB1 catenin beta 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:733705 W RGD:9068941 20211008 PID PID:200227 18432921 CTNNB1 catenin beta 1 gene PW:0000599 altered Wnt signaling, canonical pathway ISO RGD:733705 W RGD:9068941 20211008 RGD PMID:18432252|PMID:19078924|REF_RGD_ID:2293188|REF_RGD_ID:4143515 18432921 CTNNB1 catenin beta 1 gene PW:0000611 endometrial cancer pathway ISO RGD:733705 W RGD:9068941 20211008 RGD PMID:19078924|REF_RGD_ID:4143515 18432921 CTNNB1 catenin beta 1 gene PW:0000612 colorectal cancer pathway ISO RGD:733705 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18432921 CTNNB1 catenin beta 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:733705 W RGD:9068941 20211008 PID PID:200124|PID:200147|PID:200182 18432921 CTNNB1 catenin beta 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:733705 W RGD:9068941 20211008 PID PID:200209 18432974 SRSF5 serine and arginine rich splicing factor 5 gene PW:0001073 spliceosome pathway ISO RGD:734021 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18433027 AKAP3 A-kinase anchoring protein 3 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1348905 W RGD:9068941 20211008 RGD PMID:14715913|PMID:19319965|REF_RGD_ID:2312475|REF_RGD_ID:2312477 18433055 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene PW:0000054 tryptophan metabolic pathway ISO RGD:730870 W RGD:9068941 20211008 SMPDB SMP:00063 18433055 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene PW:0000375 phase I biotransformation pathway via cytochrome P450 ISO RGD:2458 W RGD:9068941 20211008 RGD PMID:12464257|REF_RGD_ID:727674 18433055 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene PW:0000375 phase I biotransformation pathway via cytochrome P450 ISO RGD:730870 W RGD:9068941 20211008 RGD PMID:12464257|REF_RGD_ID:727674 18433055 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene PW:0000730 warfarin pharmacokinetics pathway ISO RGD:730870 W RGD:9068941 20211008 RGD PMID:26655108|REF_RGD_ID:11354883 18433055 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene PW:0000838 tamoxifen pharmacokinetics pathway ISO RGD:730870 W RGD:9068941 20211008 RGD PMID:12971802|REF_RGD_ID:5129544 18433055 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene PW:0000870 gefitinib pharmacokinetics pathway ISO RGD:730870 W RGD:9068941 20211008 RGD PMID:19733976|REF_RGD_ID:5135288 18433154 ERN1 endoplasmic reticulum to nucleus signaling 1 gene PW:0000379 endoplasmic reticulum stress - the unfolded protein response pathway ISO RGD:1605125 W RGD:9068941 20211008 RGD PMID:22733998|REF_RGD_ID:10450872 18433324 MED12L mediator complex subunit 12L gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1352033 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18433519 PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1346928 W RGD:9068941 20211008 PID PID:200149 18433519 PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1346928 W RGD:9068941 20211008 PID PID:200142 18433519 PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 gene PW:0000565 eicosanoid signaling pathway ISO RGD:1346928 W RGD:9068941 20211008 PID PID:200082 18433519 PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:1346928 W RGD:9068941 20211008 PID PID:200116 18433585 ASRGL1 asparaginase and isoaspartyl peptidase 1 gene PW:0001417 Canavan disease pathway ISO RGD:1343525 W RGD:9068941 20211008 SMPDB SMP:00175 18433957 APOC3 apolipoprotein C3 gene PW:0000482 lipoprotein metabolic pathway ISO RGD:737569 W RGD:9068941 20211008 RGD PMID:10073946|REF_RGD_ID:1578471 18433957 APOC3 apolipoprotein C3 gene PW:0000484 altered lipoprotein metabolic pathway ISO RGD:737569 W RGD:9068941 20211008 RGD PMID:10073946|REF_RGD_ID:1578471 18434041 PRPF6 pre-mRNA processing factor 6 gene PW:0001073 spliceosome pathway ISO RGD:1316097 W RGD:9068941 20211008 RGD PMID:19239890|REF_RGD_ID:9686089 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00133 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00132 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00134 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001880 iminoglycinuria pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00193 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00105 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0001977 Hartnup disease pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00189 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00100 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00115 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00097 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00122 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00088 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00078 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00090 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002214 cystinuria pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00723 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00118 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00135 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00121 18434169 SLC7A9 solute carrier family 7 member 9 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:734403 W RGD:9068941 20211008 SMPDB SMP:00108 18434240 AXIN2 axin 2 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1349667 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18434240 AXIN2 axin 2 gene PW:0000599 altered Wnt signaling, canonical pathway ISO RGD:1349667 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18434240 AXIN2 axin 2 gene PW:0000611 endometrial cancer pathway ISO RGD:1349667 W RGD:9068941 20211008 RGD PMID:25144715|REF_RGD_ID:13432159 18434240 AXIN2 axin 2 gene PW:0000612 colorectal cancer pathway ISO RGD:1349667 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18434278 DRD5 dopamine receptor D5 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:731837 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18434278 DRD5 dopamine receptor D5 gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:731837 W RGD:9068941 20211008 RGD PMID:25671228|REF_RGD_ID:11041142 18434278 DRD5 dopamine receptor D5 gene PW:0000394 dopamine signaling pathway ISO RGD:731837 W RGD:9068941 20211008 RGD PMID:25671228|REF_RGD_ID:11041142 18434278 DRD5 dopamine receptor D5 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:731837 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18434410 PDK4 pyruvate dehydrogenase kinase 4 gene PW:0000043 pyruvate metabolic pathway ISO RGD:69113 W RGD:9068941 20211008 RGD PMID:11795479|PMID:17310282|REF_RGD_ID:2307427|REF_RGD_ID:2307428 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:70500 W RGD:9068941 20211008 RGD PMID:12097495|PMID:16955078|PMID:17310240|REF_RGD_ID:1626216|REF_RGD_ID:628468|REF_RGD_ID:8553011 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:732502 W RGD:9068941 20211008 RGD PMID:12835716|REF_RGD_ID:1357969 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000143 insulin signaling pathway ISO RGD:732502 W RGD:9068941 20211008 SMPDB SMP:00391 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200101 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000180 mTOR signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200096 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200188 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200149 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:732502 W RGD:9068941 20211008 PID PID:200052 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200220 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200144 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000506 endothelin signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200005 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000659 syndecan signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200156|PID:200192 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000682 Trail mediated signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200068 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000896 type II interferon signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200129 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200098 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200046|PID:200054|PID:200085|PID:200211 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000961 ceramide signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200119 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:732502 W RGD:9068941 20211008 PID PID:200019 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0000998 adenosine signaling pathway ISO RGD:732502 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18434429 MAPK1 mitogen-activated protein kinase 1 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:732502 W RGD:9068941 20211008 SMPDB SMP:00358 18434728 PSEN1 presenilin 1 gene PW:0000204 Notch signaling pathway ISO RGD:3425 W RGD:9068941 20211008 RGD PMID:12736250|REF_RGD_ID:724403 18434728 PSEN1 presenilin 1 gene PW:0000204 Notch signaling pathway ISO RGD:731724 W RGD:9068941 20211008 PID PID:200015 18434728 PSEN1 presenilin 1 gene PW:0000204 Notch signaling pathway ISO RGD:731724 W RGD:9068941 20211008 RGD PMID:14986688|PMID:17761886|REF_RGD_ID:1334462|REF_RGD_ID:2302204 18434728 PSEN1 presenilin 1 gene PW:0000659 syndecan signaling pathway ISO RGD:731724 W RGD:9068941 20211008 PID PID:200198 18435015 DYNLL2 dynein light chain LC8-type 2 gene PW:0002061 mitochondria transport pathway ISO RGD:730979 W RGD:9068941 20211008 RGD PMID:21936784|REF_RGD_ID:10402142 18435147 PPARGC1A PPARG coactivator 1 alpha gene PW:0000180 mTOR signaling pathway ISO RGD:1342674 W RGD:9068941 20211008 PID PID:200096 18435147 PPARGC1A PPARG coactivator 1 alpha gene PW:0000568 aldosterone signaling pathway ISO RGD:1342674 W RGD:9068941 20211008 RGD PMID:21784126|REF_RGD_ID:7421504 18435446 TREH trehalase gene PW:0001300 trehalose degradation pathway ISO RGD:736593 W RGD:9068941 20211008 SMPDB SMP:00467 18435579 GLDC glycine decarboxylase gene PW:0001207 folate cycle metabolic pathway ISO RGD:1318561 W RGD:9068941 20211008 RGD PMID:20645850|REF_RGD_ID:7242560 18435579 GLDC glycine decarboxylase gene PW:0001670 sarcosinemia pathway ISO RGD:1318561 W RGD:9068941 20211008 SMPDB SMP:00244 18435579 GLDC glycine decarboxylase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1318561 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18435579 GLDC glycine decarboxylase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1318561 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18435579 GLDC glycine decarboxylase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1318561 W RGD:9068941 20211008 SMPDB SMP:00179 18435613 RPL37 ribosomal protein L37 gene PW:0000101 translation pathway ISO RGD:731374 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18435613 RPL37 ribosomal protein L37 gene PW:0001066 ribosome biogenesis pathway ISO RGD:731374 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18435777 SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:1343139 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18435859 MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component gene PW:0002636 cytosolic iron-sulfur cluster protein assembly pathway ISO RGD:1354311 W RGD:9068941 20211008 RGD PMID:25245479|PMID:25583461|REF_RGD_ID:11554190|REF_RGD_ID:11554192 18435904 TNNT2 troponin T2, cardiac type gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00296 18435904 TNNT2 troponin T2, cardiac type gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00379 18435904 TNNT2 troponin T2, cardiac type gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00665 18435904 TNNT2 troponin T2, cardiac type gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00376 18435904 TNNT2 troponin T2, cardiac type gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00375 18435904 TNNT2 troponin T2, cardiac type gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00659 18435904 TNNT2 troponin T2, cardiac type gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00660 18435904 TNNT2 troponin T2, cardiac type gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00323 18435904 TNNT2 troponin T2, cardiac type gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00307 18435904 TNNT2 troponin T2, cardiac type gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00324 18435904 TNNT2 troponin T2, cardiac type gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00380 18435904 TNNT2 troponin T2, cardiac type gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00381 18435904 TNNT2 troponin T2, cardiac type gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00382 18435904 TNNT2 troponin T2, cardiac type gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00366 18435904 TNNT2 troponin T2, cardiac type gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00302 18435904 TNNT2 troponin T2, cardiac type gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00378 18435904 TNNT2 troponin T2, cardiac type gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00332 18435904 TNNT2 troponin T2, cardiac type gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00331 18435904 TNNT2 troponin T2, cardiac type gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00301 18435904 TNNT2 troponin T2, cardiac type gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00325 18435904 TNNT2 troponin T2, cardiac type gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00359 18435904 TNNT2 troponin T2, cardiac type gene PW:0002134 bupranolol drug pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00670 18435904 TNNT2 troponin T2, cardiac type gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00670 18435904 TNNT2 troponin T2, cardiac type gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00300 18435904 TNNT2 troponin T2, cardiac type gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00299 18435904 TNNT2 troponin T2, cardiac type gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00296 18435904 TNNT2 troponin T2, cardiac type gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00298 18435904 TNNT2 troponin T2, cardiac type gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00305 18435904 TNNT2 troponin T2, cardiac type gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00303 18435904 TNNT2 troponin T2, cardiac type gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00306 18435904 TNNT2 troponin T2, cardiac type gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00326 18435904 TNNT2 troponin T2, cardiac type gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00666 18435904 TNNT2 troponin T2, cardiac type gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00327 18435904 TNNT2 troponin T2, cardiac type gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00329 18435904 TNNT2 troponin T2, cardiac type gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00662 18435904 TNNT2 troponin T2, cardiac type gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00663 18435904 TNNT2 troponin T2, cardiac type gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00328 18435904 TNNT2 troponin T2, cardiac type gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:732398 W RGD:9068941 20211008 SMPDB SMP:00367 18436068 CRABP1 cellular retinoic acid binding protein 1 gene PW:0001004 retinoic acid metabolic pathway ISO RGD:1345653 W RGD:9068941 20211008 RGD PMID:21621639|REF_RGD_ID:6484672 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0000031 purine metabolic pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00050 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001590 xanthinuria pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00220 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001591 xanthinuria type I pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00512 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001592 xanthinuria type II pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00513 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00210 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00537 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00203 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00364 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00365 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00428 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00427 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00167 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0002294 AICA-ribosuria pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00168 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00430 18436092 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:1343601 W RGD:9068941 20211008 SMPDB SMP:00535 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000061 long term depression ISO RGD:70982 W RGD:9068941 20211008 RGD PMID:17329210|REF_RGD_ID:1641844 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000122 Hedgehog signaling pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200172 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000122 Hedgehog signaling pathway ISO RGD:733891 W RGD:9068941 20211008 RGD PMID:20635334|REF_RGD_ID:5510026 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:70982 W RGD:9068941 20211008 RGD PMID:16478782|PMID:20042609|REF_RGD_ID:1581696|REF_RGD_ID:7242068 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200077 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:733891 W RGD:9068941 20211008 RGD PMID:18432252|REF_RGD_ID:2293188 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200197 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200144 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:733891 W RGD:9068941 20211008 RGD PMID:25937177|REF_RGD_ID:11535070 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000388 Reelin signaling pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200062 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000532 glycogen biosynthetic pathway ISO RGD:733891 W RGD:9068941 20211008 RGD PMID:17530463|REF_RGD_ID:2306093 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200196 18436134 GSK3B glycogen synthase kinase 3 beta gene PW:0000718 p53 signaling pathway ISO RGD:733891 W RGD:9068941 20211008 PID PID:200206 18436341 LOC103231895 serine/threonine-protein kinase A-Raf gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:1348364 W RGD:9068941 20211008 RGD PMID:22177953|REF_RGD_ID:5686410 18436520 PIM1 Pim-1 proto-oncogene, serine/threonine kinase gene PW:0000968 interleukin-3 signaling pathway ISO RGD:737516 W RGD:9068941 20211008 PID PID:200145 18436520 PIM1 Pim-1 proto-oncogene, serine/threonine kinase gene PW:0000969 interleukin-5 signaling pathway ISO RGD:737516 W RGD:9068941 20211008 PID PID:200107 18436520 PIM1 Pim-1 proto-oncogene, serine/threonine kinase gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:737516 W RGD:9068941 20211008 PID PID:200019 18436554 SKP2 S-phase kinase associated protein 2 gene PW:0000204 Notch signaling pathway ISO RGD:1607086 W RGD:9068941 20211008 PID PID:200015 18436554 SKP2 S-phase kinase associated protein 2 gene PW:0000718 p53 signaling pathway ISO RGD:1607086 W RGD:9068941 20211008 PID PID:200206 18436584 RPP30 ribonuclease P/MRP subunit p30 gene PW:0001573 tRNA maturation pathway ISO RGD:1321878 W RGD:9068941 20211008 RGD PMID:19931535|REF_RGD_ID:9685326 18436735 CHEK1 checkpoint kinase 1 gene PW:0000384 G2/M DNA damage checkpoint pathway ISO RGD:620545 W RGD:9068941 20211008 RGD PMID:11278490|REF_RGD_ID:2316109 18436735 CHEK1 checkpoint kinase 1 gene PW:0000718 p53 signaling pathway ISO RGD:732292 W RGD:9068941 20211008 PID PID:200206 18436735 CHEK1 checkpoint kinase 1 gene PW:0000718 p53 signaling pathway ISO RGD:732292 W RGD:9068941 20211008 RGD PMID:16601750|PMID:19450511|REF_RGD_ID:2316155|REF_RGD_ID:2316156 18436777 TOMM22 translocase of outer mitochondrial membrane 22 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1342792 W RGD:9068941 20211008 RGD PMID:25542066|PMID:25633533|REF_RGD_ID:10412658|REF_RGD_ID:10412659 18436777 TOMM22 translocase of outer mitochondrial membrane 22 gene PW:0002138 carrier pathway of mitochondrial protein import ISO RGD:1342792 W RGD:9068941 20211008 RGD PMID:25980382|REF_RGD_ID:10412661 18436777 TOMM22 translocase of outer mitochondrial membrane 22 gene PW:0002140 beta-barrel pathway of mitochondrial protein import ISO RGD:1342792 W RGD:9068941 20211008 RGD PMID:25305573|REF_RGD_ID:10412662 18436908 CHRNB3 cholinergic receptor nicotinic beta 3 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:1347400 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000122 Hedgehog signaling pathway ISO RGD:730824 W RGD:9068941 20211008 PID PID:200172 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:730824 W RGD:9068941 20211008 PID PID:200101 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:2713 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:730824 W RGD:9068941 20211008 RGD PMID:23759942|REF_RGD_ID:8549590 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000506 endothelin signaling pathway ISO RGD:730824 W RGD:9068941 20211008 PID PID:200005 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000586 orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2 ISO RGD:2713 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000856 acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family ISO RGD:730824 W RGD:9068941 20211008 RGD PMID:23759942|REF_RGD_ID:8549590 18436921 GNAI1 G protein subunit alpha i1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:730824 W RGD:9068941 20211008 PID PID:200046|PID:200054|PID:200076|PID:200085|PID:200123|PID:200211 18436936 POLR2H RNA polymerase II, I and III subunit H gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1314889 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18436936 POLR2H RNA polymerase II, I and III subunit H gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1314889 W RGD:9068941 20211008 RGD PMID:22960599|REF_RGD_ID:9588243 18436936 POLR2H RNA polymerase II, I and III subunit H gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1314889 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18437097 COL4A6 collagen type IV alpha 6 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1343037 W RGD:9068941 20211008 PID PID:200156 18437173 LRP8 LDL receptor related protein 8 gene PW:0000388 Reelin signaling pathway ISO RGD:1313932 W RGD:9068941 20211008 PID PID:200062 18437173 LRP8 LDL receptor related protein 8 gene PW:0000388 Reelin signaling pathway ISO RGD:1313932 W RGD:9068941 20211008 RGD PMID:19846452|REF_RGD_ID:2324974 18437173 LRP8 LDL receptor related protein 8 gene PW:0000390 altered Reelin signaling pathway ISO RGD:1313932 W RGD:9068941 20211008 RGD PMID:19846452|REF_RGD_ID:2324974 18437284 HMBS hydroxymethylbilane synthase gene PW:0000218 heme biosynthetic pathway ISO RGD:2801 W RGD:9068941 20211008 RGD PMID:1781034|PMID:593266|PMID:6694518|PMID:6712591|PMID:6893114|REF_RGD_ID:2301704|REF_RGD_ID:25330343|REF_RGD_ID:25440495|REF_RGD_ID:26884337|REF_RGD_ID:26923963 18437284 HMBS hydroxymethylbilane synthase gene PW:0000218 heme biosynthetic pathway ISO RGD:733095 W RGD:9068941 20211008 RGD PMID:16839620|PMID:26785297|REF_RGD_ID:11554188|REF_RGD_ID:4144542 18437284 HMBS hydroxymethylbilane synthase gene PW:0001785 variegate porphyria pathway ISO RGD:733095 W RGD:9068941 20211008 SMPDB SMP:00346 18437284 HMBS hydroxymethylbilane synthase gene PW:0001981 hereditary coproporphyria pathway ISO RGD:733095 W RGD:9068941 20211008 SMPDB SMP:00342 18437284 HMBS hydroxymethylbilane synthase gene PW:0002017 acute intermittent porphyria pathway ISO RGD:733095 W RGD:9068941 20211008 SMPDB SMP:00344 18437284 HMBS hydroxymethylbilane synthase gene PW:0002216 erythropoietic porphyria pathway ISO RGD:733095 W RGD:9068941 20211008 SMPDB SMP:00345 18437284 HMBS hydroxymethylbilane synthase gene PW:0002285 porphyrin metabolic pathway ISO RGD:733095 W RGD:9068941 20211008 SMPDB SMP:00024 18437547 NUDT21 nudix hydrolase 21 gene PW:0001332 RNA polymerase II transcription termination pathway ISO RGD:1313996 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18437547 NUDT21 nudix hydrolase 21 gene PW:0001579 3'-end pre-mRNA processing pathway ISO RGD:1313996 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18437587 ITGB1 integrin subunit beta 1 gene PW:0000286 integrin mediated signaling pathway ISO RGD:2927 W RGD:9068941 20211008 RGD PMID:12639933|REF_RGD_ID:1625134 18437587 ITGB1 integrin subunit beta 1 gene PW:0000286 integrin mediated signaling pathway ISO RGD:736631 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18437587 ITGB1 integrin subunit beta 1 gene PW:0000302 glomerulonephritis pathway ISO RGD:2927 W RGD:9068941 20211008 RGD PMID:10504498|REF_RGD_ID:633055 18437587 ITGB1 integrin subunit beta 1 gene PW:0000388 Reelin signaling pathway ISO RGD:733764 W RGD:9068941 20211008 RGD PMID:15583703|REF_RGD_ID:2325851 18437587 ITGB1 integrin subunit beta 1 gene PW:0000388 Reelin signaling pathway ISO RGD:736631 W RGD:9068941 20211008 PID PID:200062 18437587 ITGB1 integrin subunit beta 1 gene PW:0000390 altered Reelin signaling pathway ISO RGD:733764 W RGD:9068941 20211008 RGD PMID:15583703|REF_RGD_ID:2325851 18437587 ITGB1 integrin subunit beta 1 gene PW:0000659 syndecan signaling pathway ISO RGD:736631 W RGD:9068941 20211008 PID PID:200134|PID:200192 18437638 DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 gene PW:0002061 mitochondria transport pathway ISO RGD:1344148 W RGD:9068941 20211008 RGD PMID:21936784|REF_RGD_ID:10402142 18437802 EFNB1 ephrin B1 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:2540 W RGD:9068941 20211008 RGD PMID:12139920|REF_RGD_ID:727396 18437802 EFNB1 ephrin B1 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:737327 W RGD:9068941 20211008 PID PID:200052|PID:200204 18437857 RPL36 ribosomal protein L36 gene PW:0000101 translation pathway ISO RGD:736673 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18437857 RPL36 ribosomal protein L36 gene PW:0001066 ribosome biogenesis pathway ISO RGD:736673 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18437871 PARK7 Parkinsonism associated deglycase gene PW:0000018 Parkinson's disease pathway ISO RGD:1344212 W RGD:9068941 20211008 RGD PMID:23766857|REF_RGD_ID:10450523 18437871 PARK7 Parkinsonism associated deglycase gene PW:0000206 transforming growth factor-beta signaling pathway ISO RGD:621808 W RGD:9068941 20220128 RGD PMID:29069575|REF_RGD_ID:151347449 18437901 TGFBR1 transforming growth factor beta receptor 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:3852 W RGD:9068941 20211008 RGD PMID:18684975|REF_RGD_ID:2302517 18437901 TGFBR1 transforming growth factor beta receptor 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:733386 W RGD:9068941 20211008 PID PID:200227 18437901 TGFBR1 transforming growth factor beta receptor 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:733386 W RGD:9068941 20211008 RGD PMID:12809600|REF_RGD_ID:2298922 18437901 TGFBR1 transforming growth factor beta receptor 1 gene PW:0000612 colorectal cancer pathway ISO RGD:733386 W RGD:9068941 20211008 RGD PMID:17613544|REF_RGD_ID:2306282 18437901 TGFBR1 transforming growth factor beta receptor 1 gene PW:0000614 altered transforming growth factor-beta Smad dependent signaling pathway ISO RGD:733386 W RGD:9068941 20211008 RGD PMID:17613544|PMID:18313409|REF_RGD_ID:2299005|REF_RGD_ID:2306282 18437901 TGFBR1 transforming growth factor beta receptor 1 gene PW:0000658 glypican signaling pathway ISO RGD:733386 W RGD:9068941 20211008 PID PID:200026 18437925 SNRPF small nuclear ribonucleoprotein polypeptide F gene PW:0001073 spliceosome pathway ISO RGD:1313451 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18438097 NAPRT nicotinate phosphoribosyltransferase gene PW:0001375 nicotinamide adenine dinucleotide biosynthesis, the salvage pathway ISO RGD:1602193 W RGD:9068941 20211008 RGD PMID:20007326|REF_RGD_ID:11099972 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0000174 metabolic syndrome X pathway ISO RGD:2803 W RGD:9068941 20211008 RGD PMID:19461650|REF_RGD_ID:5508692 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:731579 W RGD:9068941 20211008 RGD PMID:16876788|REF_RGD_ID:2316857 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00023 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0000728 statin pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 RGD PMID:18563955|REF_RGD_ID:4892116 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0000728 statin pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0001586 Wolman disease pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00389 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0001812 mevalonic aciduria pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00112 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0001933 hypercholesterolemia pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00209 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00079 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002106 desmosterolosis pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00386 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00095 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00117 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00107 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00508 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00387 18438138 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:731579 W RGD:9068941 20211008 SMPDB SMP:00388 18438185 FRZB frizzled related protein gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1322704 W RGD:9068941 20211008 RGD PMID:23085770|REF_RGD_ID:7365107 18438281 UBA3 ubiquitin like modifier activating enzyme 3 gene PW:0000415 proteasome degradation pathway involving cullin-dependent ubiquitin ligases ISO RGD:621084 W RGD:9068941 20211008 RGD PMID:11818503|REF_RGD_ID:634396 18438281 UBA3 ubiquitin like modifier activating enzyme 3 gene PW:0000435 neddylation pathway ISO RGD:621084 W RGD:9068941 20211008 RGD PMID:11818503|REF_RGD_ID:634396 18438324 EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 gene PW:0000379 endoplasmic reticulum stress - the unfolded protein response pathway ISO RGD:1354090 W RGD:9068941 20211008 RGD PMID:22733998|REF_RGD_ID:10450872 18438583 HNRNPM heterogeneous nuclear ribonucleoprotein M gene PW:0001073 spliceosome pathway ISO RGD:731710 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18438777 TRPV6 transient receptor potential cation channel subfamily V member 6 gene PW:0001139 calcium transport pathway ISO RGD:731367 W RGD:9068941 20211008 RGD PMID:20716668|REF_RGD_ID:7204689 18438777 TRPV6 transient receptor potential cation channel subfamily V member 6 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:731367 W RGD:9068941 20211008 RGD PMID:20716668|REF_RGD_ID:7204689 18438807 LCP2 lymphocyte cytosolic protein 2 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:732713 W RGD:9068941 20211008 SMPDB SMP:00358 18438876 GLS2 glutaminase 2 gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00072 18438876 GLS2 glutaminase 2 gene PW:0000076 urea cycle pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00059 18438876 GLS2 glutaminase 2 gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18438876 GLS2 glutaminase 2 gene PW:0001806 ornithine carbamoyltransferase deficiency pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00205 18438876 GLS2 glutaminase 2 gene PW:0001979 homocarnosinosis pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00385 18438876 GLS2 glutaminase 2 gene PW:0002143 citrullinemia pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00001 18438876 GLS2 glutaminase 2 gene PW:0002145 argininosuccinic aciduria pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00003 18438876 GLS2 glutaminase 2 gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00136 18438876 GLS2 glutaminase 2 gene PW:0002220 carbamoyl phosphate synthetase I deficiency pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00002 18438876 GLS2 glutaminase 2 gene PW:0002290 hyperargininemia pathway ISO RGD:1604019 W RGD:9068941 20211008 SMPDB SMP:00357 18438936 DCTN5 dynactin subunit 5 gene PW:0002061 mitochondria transport pathway ISO RGD:1603378 W RGD:9068941 20211008 RGD PMID:15473859|REF_RGD_ID:10402155 18439182 MTUS1 microtubule associated scaffold protein 1 gene PW:0000528 angiotensin II signaling pathway via AT2 receptor ISO RGD:1343554 W RGD:9068941 20211008 RGD PMID:20889352|REF_RGD_ID:5133679 18439232 CD3D CD3d molecule gene PW:0000914 interleukin-12 signaling pathway ISO RGD:736987 W RGD:9068941 20211008 PID PID:200045 18439415 POLE DNA polymerase epsilon, catalytic subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1348983 W RGD:9068941 20211008 RGD PMID:12806123|PMID:21601536|REF_RGD_ID:7246935|REF_RGD_ID:7246936 18439415 POLE DNA polymerase epsilon, catalytic subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1348983 W RGD:9068941 20211008 SMPDB SMP:00478 18439553 ATP2C1 ATPase secretory pathway Ca2+ transporting 1 gene PW:0001139 calcium transport pathway ISO RGD:733912 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18439553 ATP2C1 ATPase secretory pathway Ca2+ transporting 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:733912 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18439732 PARP12 poly(ADP-ribose) polymerase family member 12 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1318511 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18440006 CACNA1F calcium voltage-gated channel subunit alpha1 F gene PW:0001139 calcium transport pathway ISO RGD:731992 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18440006 CACNA1F calcium voltage-gated channel subunit alpha1 F gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:731992 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0000031 purine metabolic pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00050 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0000867 de novo purine biosynthetic pathway ISO RGD:1321450 W RGD:9068941 20211008 RGD PMID:10218106|REF_RGD_ID:5143930 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001590 xanthinuria pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00220 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001591 xanthinuria type I pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00512 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001592 xanthinuria type II pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00513 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00210 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00537 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00203 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00364 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00365 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00428 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00427 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00167 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0002294 AICA-ribosuria pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00168 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00430 18440340 ADSS2 adenylosuccinate synthase 2 gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:1321450 W RGD:9068941 20211008 SMPDB SMP:00535 18440449 PPP2R3A protein phosphatase 2 regulatory subunit B''alpha gene PW:0000394 dopamine signaling pathway ISO RGD:1315869 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18440709 TPI1 triosephosphate isomerase 1 gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00064 18440709 TPI1 triosephosphate isomerase 1 gene PW:0000640 glycolysis pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00040 18440709 TPI1 triosephosphate isomerase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00128 18440709 TPI1 triosephosphate isomerase 1 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00563 18440709 TPI1 triosephosphate isomerase 1 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18440709 TPI1 triosephosphate isomerase 1 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00573 18440709 TPI1 triosephosphate isomerase 1 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00531 18440709 TPI1 triosephosphate isomerase 1 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00562 18440709 TPI1 triosephosphate isomerase 1 gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00725 18440709 TPI1 triosephosphate isomerase 1 gene PW:0002360 Fanconi syndrome pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00572 18440709 TPI1 triosephosphate isomerase 1 gene PW:0002388 fructosuria pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00561 18440709 TPI1 triosephosphate isomerase 1 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:737023 W RGD:9068941 20211008 SMPDB SMP:00560 18440750 SIRT3 sirtuin 3 gene PW:0001338 histone modification pathway ISO RGD:1318106 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18440750 SIRT3 sirtuin 3 gene PW:0002584 Sirtuin mediated pathway ISO RGD:1318106 W RGD:9068941 20211008 RGD PMID:26785480|REF_RGD_ID:11100032 18440937 FGF1 fibroblast growth factor 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:735698 W RGD:9068941 20211008 PID PID:200220 18441041 PPP2R5D protein phosphatase 2 regulatory subunit B'delta gene PW:0000394 dopamine signaling pathway ISO RGD:1315410 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18441041 PPP2R5D protein phosphatase 2 regulatory subunit B'delta gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1315410 W RGD:9068941 20211008 PID PID:200098 18441187 NEU3 neuraminidase 3 gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1347886 W RGD:9068941 20211008 SMPDB SMP:00034 18441187 NEU3 neuraminidase 3 gene PW:0001454 Gaucher's disease pathway ISO RGD:1347886 W RGD:9068941 20211008 SMPDB SMP:00349 18441187 NEU3 neuraminidase 3 gene PW:0002021 Krabbe disease pathway ISO RGD:1347886 W RGD:9068941 20211008 SMPDB SMP:00348 18441187 NEU3 neuraminidase 3 gene PW:0002103 Fabry disease pathway ISO RGD:1347886 W RGD:9068941 20211008 SMPDB SMP:00525 18441187 NEU3 neuraminidase 3 gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1347886 W RGD:9068941 20211008 SMPDB SMP:00347 18441229 PGK1 phosphoglycerate kinase 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1353723 W RGD:9068941 20211008 PID PID:200036|PID:200202 18441229 PGK1 phosphoglycerate kinase 1 gene PW:0000640 glycolysis pathway ISO RGD:619878 W RGD:9068941 20211008 RGD PMID:3091090|PMID:6405813|REF_RGD_ID:2302859|REF_RGD_ID:2302860 18441229 PGK1 phosphoglycerate kinase 1 gene PW:0000641 gluconeogenesis pathway ISO RGD:619878 W RGD:9068941 20211008 RGD PMID:15720133|PMID:3091090|REF_RGD_ID:2302795|REF_RGD_ID:2302860 18441229 PGK1 phosphoglycerate kinase 1 gene PW:0001431 lamivudine pharmacokinetics pathway ISO RGD:1353723 W RGD:9068941 20211008 SMPDB SMP:00649 18441311 VEGFB vascular endothelial growth factor B gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1343221 W RGD:9068941 20211008 RGD PMID:16633338|REF_RGD_ID:2298727 18441399 BECN1 beclin 1 gene PW:0000046 inositol metabolic pathway ISO RGD:733440 W RGD:9068941 20211008 SMPDB SMP:00011 18441399 BECN1 beclin 1 gene PW:0000278 autophagy pathway ISO RGD:620190 W RGD:9068941 20211008 RGD PMID:16697404|REF_RGD_ID:1643194 18441399 BECN1 beclin 1 gene PW:0000278 autophagy pathway ISO RGD:733440 W RGD:9068941 20211008 RGD PMID:15325588|PMID:20034776|REF_RGD_ID:1643329|REF_RGD_ID:4889529 18441399 BECN1 beclin 1 gene PW:0001842 mitochondrial autophagy pathway ISO RGD:733440 W RGD:9068941 20211008 RGD PMID:23065344|REF_RGD_ID:10401098 18441399 BECN1 beclin 1 gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:733440 W RGD:9068941 20211008 SMPDB SMP:00463 18441448 LOC103247994 DNA-binding protein inhibitor ID-1 gene PW:0000968 interleukin-3 signaling pathway ISO RGD:736819 W RGD:9068941 20211008 PID PID:200145 18441516 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1603623 W RGD:9068941 20211008 PID PID:200144 18441516 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1603623 W RGD:9068941 20211008 PID PID:200227 18441516 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1603623 W RGD:9068941 20211008 RGD PMID:12809600|REF_RGD_ID:2298922 18441595 DICER1 dicer 1, ribonuclease III gene PW:0000808 microRNA pathway ISO RGD:1319699 W RGD:9068941 20211008 RGD PMID:20661255|REF_RGD_ID:4144851 18441692 LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated gene PW:0001073 spliceosome pathway ISO RGD:1314318 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00296 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00671 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00379 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001300 trehalose degradation pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00467 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001364 lactose degradation pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00457 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00431 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00413 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00133 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00665 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00376 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00375 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00659 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00132 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00134 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00660 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00323 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00307 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00402 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00324 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001880 iminoglycinuria pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00193 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00686 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00380 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00381 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00382 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00366 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00687 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00691 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00105 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00302 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00408 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00399 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00378 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001977 Hartnup disease pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00189 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00422 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00332 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00100 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00115 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00426 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00331 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00415 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00097 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00301 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00425 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00325 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00359 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00423 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00424 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00122 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002134 bupranolol drug pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00670 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00670 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00088 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00300 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00299 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00296 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00078 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00684 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00393 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00090 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002214 cystinuria pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00723 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00298 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00305 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00401 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00404 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00118 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00303 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00306 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00135 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00688 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00326 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00666 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00121 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00327 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00329 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00416 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00108 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00662 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00397 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00409 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00410 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00411 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00412 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00394 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00663 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00681 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00395 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00328|SMP:00398 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00400 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00677 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00673 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00407 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00675 18441796 ATP1B1 ATPase Na+/K+ transporting subunit beta 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:735774 W RGD:9068941 20211008 SMPDB SMP:00367 18441806 SETD1A SET domain containing 1A, histone lysine methyltransferase gene PW:0001338 histone modification pathway ISO RGD:1605414 W RGD:9068941 20211008 RGD PMID:22663077|PMID:23200123|REF_RGD_ID:7242632|REF_RGD_ID:9479053 18441883 GLRX5 glutaredoxin 5 gene PW:0002635 mitochondrial iron-sulfur cluster protein biogenesis pathway ISO RGD:1318119 W RGD:9068941 20211008 RGD PMID:25245479|REF_RGD_ID:11554190 18441964 SLC22A16 solute carrier family 22 member 16 gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:1344136 W RGD:9068941 20211008 RGD PMID:21048526|REF_RGD_ID:10395261 18441964 SLC22A16 solute carrier family 22 member 16 gene PW:0001565 doxorubicin pharmacokinetics pathway ISO RGD:1344136 W RGD:9068941 20211008 SMPDB SMP:00650 18442025 PPP2R2B protein phosphatase 2 regulatory subunit Bbeta gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1352838 W RGD:9068941 20211008 PID PID:200149 18442070 SLC18A2 solute carrier family 18 member A2 gene PW:0000802 dopamine biosynthetic pathway ISO RGD:3694 W RGD:9068941 20211008 RGD PMID:19903816|REF_RGD_ID:5128868 18442070 SLC18A2 solute carrier family 18 member A2 gene PW:0000803 epinephrine biosynthetic pathway ISO RGD:3694 W RGD:9068941 20211008 RGD PMID:19903816|REF_RGD_ID:5128868 18442070 SLC18A2 solute carrier family 18 member A2 gene PW:0000804 norepinephrine biosynthetic pathway ISO RGD:3694 W RGD:9068941 20211008 RGD PMID:19903816|REF_RGD_ID:5128868 18442264 STEAP3 STEAP3 metalloreductase gene PW:0002631 iron uptake pathway ISO RGD:1605372 W RGD:9068941 20211008 RGD PMID:25661197|REF_RGD_ID:11554199 18442448 DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease gene PW:0001066 ribosome biogenesis pathway ISO RGD:1312206 W RGD:9068941 20211008 RGD PMID:25346433|REF_RGD_ID:9999448 18442557 SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 gene PW:0001073 spliceosome pathway ISO RGD:1316126 W RGD:9068941 20211008 RGD PMID:23592432|REF_RGD_ID:9686090 18442704 CDC37 cell division cycle 37, HSP90 cochaperone gene PW:0000840 protein kinase C (PKC) signaling pathway ISO RGD:732258 W RGD:9068941 20211008 RGD PMID:19934406|REF_RGD_ID:5131489 18442764 SNAPC3 small nuclear RNA activating complex polypeptide 3 gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1313043 W RGD:9068941 20211008 RGD PMID:23031840|REF_RGD_ID:9588284 18443053 PDE6B phosphodiesterase 6B gene PW:0000962 visual phototransduction pathway ISO RGD:1322283 W RGD:9068941 20211008 RGD PMID:15224133|REF_RGD_ID:6893540 18443053 PDE6B phosphodiesterase 6B gene PW:0001495 altered visual phototransduction pathway ISO RGD:1322283 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18443053 PDE6B phosphodiesterase 6B gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1322283 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18443216 LEP leptin gene PW:0000357 energy homeostasis pathway ISO RGD:3000 W RGD:9068941 20211008 RGD PMID:12058043|REF_RGD_ID:625499 18443216 LEP leptin gene PW:0000357 energy homeostasis pathway ISO RGD:69123 W RGD:9068941 20211008 RGD PMID:12079865|REF_RGD_ID:1357909 18443216 LEP leptin gene PW:0000357 energy homeostasis pathway ISO RGD:69124 W RGD:9068941 20211008 RGD PMID:17010638|REF_RGD_ID:1625125 18443216 LEP leptin gene PW:0000359 altered energy homeostasis pathway ISO RGD:3000 W RGD:9068941 20211008 RGD PMID:11102451|REF_RGD_ID:61790 18443216 LEP leptin gene PW:0000359 altered energy homeostasis pathway ISO RGD:69123 W RGD:9068941 20211008 RGD PMID:15703762|REF_RGD_ID:1357910 18443216 LEP leptin gene PW:0000360 hypoxia inducible factor pathway ISO RGD:69123 W RGD:9068941 20211008 PID PID:200202 18443216 LEP leptin gene PW:0000363 leptin system pathway ISO RGD:3000 W RGD:9068941 20211008 RGD PMID:11102451|PMID:9070213|PMID:9618284|REF_RGD_ID:2290293|REF_RGD_ID:2290294|REF_RGD_ID:61790 18443216 LEP leptin gene PW:0000363 leptin system pathway ISO RGD:69123 W RGD:9068941 20211008 RGD PMID:12079865|REF_RGD_ID:1357909 18443216 LEP leptin gene PW:0000363 leptin system pathway ISO RGD:69124 W RGD:9068941 20211008 RGD PMID:17010638|REF_RGD_ID:1625125 18443216 LEP leptin gene PW:0000364 altered leptin system pathway ISO RGD:3000 W RGD:9068941 20211008 RGD PMID:11102451|REF_RGD_ID:61790 18443216 LEP leptin gene PW:0000364 altered leptin system pathway ISO RGD:69123 W RGD:9068941 20211008 RGD PMID:15703762|REF_RGD_ID:1357910 18443734 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1345835 W RGD:9068941 20211008 PID PID:200149 18443734 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 gene PW:0000961 ceramide signaling pathway ISO RGD:1345835 W RGD:9068941 20211008 PID PID:200119 18443834 DRD2 dopamine receptor D2 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:10486 W RGD:9068941 20211008 RGD PMID:12121979|REF_RGD_ID:1581445 18443834 DRD2 dopamine receptor D2 gene PW:0000228 G protein mediated signaling pathway via Galphai family ISO RGD:736796 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18443834 DRD2 dopamine receptor D2 gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:736796 W RGD:9068941 20211008 RGD D1-D2 heterodimer PMID:25671228|REF_RGD_ID:11041142 18443834 DRD2 dopamine receptor D2 gene PW:0000394 dopamine signaling pathway ISO RGD:2520 W RGD:9068941 20211008 RGD PMID:12121979|PMID:16490190|PMID:17314300|REF_RGD_ID:1581445|REF_RGD_ID:1625010|REF_RGD_ID:1625068 18443834 DRD2 dopamine receptor D2 gene PW:0000394 dopamine signaling pathway ISO RGD:736796 W RGD:9068941 20211008 RGD heterodimer coupled to Galphaq PMID:25671228|REF_RGD_ID:11041142 18443834 DRD2 dopamine receptor D2 gene PW:0000455 excitatory synaptic transmission pathway ISO RGD:2520 W RGD:9068941 20211008 RGD PMID:17314300|REF_RGD_ID:1625010 18443834 DRD2 dopamine receptor D2 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:736796 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0000058 fatty acid metabolic pathway ISO RGD:620512 W RGD:9068941 20211008 RGD PMID:1730633|REF_RGD_ID:1600572 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0000058 fatty acid metabolic pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00051 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0000738 fatty acid beta degradation pathway ISO RGD:733877 W RGD:9068941 20211008 RGD PMID:10816122|REF_RGD_ID:2317625 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0000738 fatty acid beta degradation pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00481|SMP:00482 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0001136 fatty acid elongation pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00054 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0001452 valproic acid pharmacokinetics pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00635 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0001594 very long-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00540 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0001627 trifunctional protein deficiency pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00545 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0001667 short-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00235 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0001869 medium chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00542 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0002206 ethylmalonic encephalopathy pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00181 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0002306 glutaric aciduria type I pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00185 18444213 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha gene PW:0002574 carnitine palmitoyltransferase I deficiency pathway ISO RGD:733877 W RGD:9068941 20211008 SMPDB SMP:00538 18444268 ETF1 eukaryotic translation termination factor 1 gene PW:0000582 translation termination pathway ISO RGD:1313906 W RGD:9068941 20211008 RGD PMID:22751155|REF_RGD_ID:10044026 18444566 ALDH1A2 aldehyde dehydrogenase 1 family member A2 gene PW:0000141 retinol metabolic pathway ISO RGD:620250 W RGD:9068941 20211008 RGD PMID:12547725|REF_RGD_ID:1576367 18444566 ALDH1A2 aldehyde dehydrogenase 1 family member A2 gene PW:0000141 retinol metabolic pathway ISO RGD:734163 W RGD:9068941 20211008 SMPDB SMP:00074 18444566 ALDH1A2 aldehyde dehydrogenase 1 family member A2 gene PW:0001004 retinoic acid metabolic pathway ISO RGD:620250 W RGD:9068941 20211008 RGD PMID:15950969|PMID:21138835|PMID:21621639|REF_RGD_ID:6484672|REF_RGD_ID:6771322|REF_RGD_ID:6771354 18444566 ALDH1A2 aldehyde dehydrogenase 1 family member A2 gene PW:0001004 retinoic acid metabolic pathway ISO RGD:734163 W RGD:9068941 20211008 RGD PMID:21621639|REF_RGD_ID:6484672 18444566 ALDH1A2 aldehyde dehydrogenase 1 family member A2 gene PW:0001585 vitamin A deficiency pathway ISO RGD:734163 W RGD:9068941 20211008 SMPDB SMP:00336 18444670 POLR2L RNA polymerase II, I and III subunit L gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1349201 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18444670 POLR2L RNA polymerase II, I and III subunit L gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1349201 W RGD:9068941 20211008 RGD PMID:22960599|REF_RGD_ID:9588243 18444670 POLR2L RNA polymerase II, I and III subunit L gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1349201 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18444678 WASF2 WASP family member 2 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1316411 W RGD:9068941 20211008 PID PID:200149 18444678 WASF2 WASP family member 2 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1316411 W RGD:9068941 20211008 PID PID:200124 18444742 ABCB11 ATP binding cassette subfamily B member 11 gene PW:0000729 statin pharmacokinetics pathway ISO RGD:619930 W RGD:9068941 20211008 RGD PMID:15901796|REF_RGD_ID:1598579 18444742 ABCB11 ATP binding cassette subfamily B member 11 gene PW:0000729 statin pharmacokinetics pathway ISO RGD:730944 W RGD:9068941 20211008 RGD PMID:15901796|PMID:17353665|REF_RGD_ID:1598579|REF_RGD_ID:2316977 18444784 EP300 E1A binding protein p300 gene PW:0000204 Notch signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 PID PID:200015 18444784 EP300 E1A binding protein p300 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1348463 W RGD:9068941 20211008 PID PID:200036|PID:200202 18444784 EP300 E1A binding protein p300 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1348463 W RGD:9068941 20211008 RGD PMID:19364912|PMID:20396958|REF_RGD_ID:6483358|REF_RGD_ID:6483503 18444784 EP300 E1A binding protein p300 gene PW:0000507 estrogen signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 RGD PMID:16394250|REF_RGD_ID:5128512 18444784 EP300 E1A binding protein p300 gene PW:0000564 androgen signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 RGD PMID:17163421|REF_RGD_ID:2326123 18444784 EP300 E1A binding protein p300 gene PW:0000569 cortisol signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 RGD PMID:11306337|REF_RGD_ID:5147892 18444784 EP300 E1A binding protein p300 gene PW:0000718 p53 signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 PID PID:200206 18444784 EP300 E1A binding protein p300 gene PW:0000896 type II interferon signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 PID PID:200129 18444784 EP300 E1A binding protein p300 gene PW:0000958 forkhead class A signaling pathway ISO RGD:1348463 W RGD:9068941 20211008 PID PID:200226 18444784 EP300 E1A binding protein p300 gene PW:0001338 histone modification pathway ISO RGD:1348463 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18444945 SFTPD surfactant protein D gene PW:0000423 surfactant homeostasis pathway ISO RGD:11287 W RGD:9068941 20211008 RGD PMID:10666121|REF_RGD_ID:4144056 18444945 SFTPD surfactant protein D gene PW:0000423 surfactant homeostasis pathway ISO RGD:3667 W RGD:9068941 20211008 RGD PMID:10666121|REF_RGD_ID:4144056 18444945 SFTPD surfactant protein D gene PW:0000958 forkhead class A signaling pathway ISO RGD:735702 W RGD:9068941 20211008 PID PID:200226 18445088 ALAD aminolevulinate dehydratase gene PW:0000218 heme biosynthetic pathway ISO RGD:736545 W RGD:9068941 20211008 RGD PMID:16839620|PMID:26785297|REF_RGD_ID:11554188|REF_RGD_ID:4144542 18445088 ALAD aminolevulinate dehydratase gene PW:0001785 variegate porphyria pathway ISO RGD:736545 W RGD:9068941 20211008 SMPDB SMP:00346 18445088 ALAD aminolevulinate dehydratase gene PW:0001981 hereditary coproporphyria pathway ISO RGD:736545 W RGD:9068941 20211008 SMPDB SMP:00342 18445088 ALAD aminolevulinate dehydratase gene PW:0002017 acute intermittent porphyria pathway ISO RGD:736545 W RGD:9068941 20211008 SMPDB SMP:00344 18445088 ALAD aminolevulinate dehydratase gene PW:0002216 erythropoietic porphyria pathway ISO RGD:736545 W RGD:9068941 20211008 SMPDB SMP:00345 18445088 ALAD aminolevulinate dehydratase gene PW:0002285 porphyrin metabolic pathway ISO RGD:736545 W RGD:9068941 20211008 SMPDB SMP:00024 18445241 ULK1 unc-51 like autophagy activating kinase 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1344835 W RGD:9068941 20211008 PID PID:200096 18445241 ULK1 unc-51 like autophagy activating kinase 1 gene PW:0000278 autophagy pathway ISO RGD:1344835 W RGD:9068941 20211008 RGD PMID:15325588|PMID:20034776|REF_RGD_ID:1643329|REF_RGD_ID:4889529 18445241 ULK1 unc-51 like autophagy activating kinase 1 gene PW:0001842 mitochondrial autophagy pathway ISO RGD:1344835 W RGD:9068941 20211008 RGD PMID:25840011|REF_RGD_ID:10400888 18445536 SLC5A7 solute carrier family 5 member 7 gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:1348839 W RGD:9068941 20211008 RGD PMID:23677775|REF_RGD_ID:8549504 18445536 SLC5A7 solute carrier family 5 member 7 gene PW:0000843 acetylcholine signaling pathway via muscarinic acetylcholine receptor ISO RGD:1348839 W RGD:9068941 20211008 RGD PMID:23677775|REF_RGD_ID:8549504 18445555 TNRC6B trinucleotide repeat containing adaptor 6B gene PW:0000808 microRNA pathway ISO RGD:1350349 W RGD:9068941 20211008 RGD PMID:20484662|REF_RGD_ID:4144862 18445611 RAB23 RAB23, member RAS oncogene family gene PW:0000122 Hedgehog signaling pathway ISO RGD:1315728 W RGD:9068941 20211008 PID PID:200172 18445823 MAML1 mastermind like transcriptional coactivator 1 gene PW:0000204 Notch signaling pathway ISO RGD:1318517 W RGD:9068941 20211008 PID PID:200015 18445823 MAML1 mastermind like transcriptional coactivator 1 gene PW:0000204 Notch signaling pathway ISO RGD:1318517 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18445951 MTX1 metaxin 1 gene PW:0002140 beta-barrel pathway of mitochondrial protein import ISO RGD:1351611 W RGD:9068941 20211008 RGD PMID:25305573|REF_RGD_ID:10412662 18446235 CHRD chordin gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1348275 W RGD:9068941 20211008 PID PID:200144 18446327 SLC9A1 solute carrier family 9 member A1 gene PW:0000506 endothelin signaling pathway ISO RGD:736585 W RGD:9068941 20211008 PID PID:200005 18446520 CTSB cathepsin B gene PW:0002401 chaperone mediated autophagy pathway ISO RGD:734437 W RGD:9068941 20211008 RGD PMID:24323530|REF_RGD_ID:10755730 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0000052 tyrosine metabolic pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00006 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0000054 tryptophan metabolic pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00063 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0001282 kynurenine metabolic pathway ISO RGD:731775 W RGD:9068941 20211008 RGD PMID:25773161|REF_RGD_ID:11062165 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0001608 tyrosinemia type I pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00218 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00429 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0002208 dopamine beta-hydroxylase deficiency pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00498 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0002277 alkaptonuria pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00169 18446855 HAAO 3-hydroxyanthranilate 3,4-dioxygenase gene PW:0002380 hawkinsinuria pathway ISO RGD:731775 W RGD:9068941 20211008 SMPDB SMP:00190 18446872 OLR1 oxidized low density lipoprotein receptor 1 gene PW:0000244 angiotensin II signaling pathway ISO RGD:620515 W RGD:9068941 20211008 RGD PMID:12661921|REF_RGD_ID:1580992 18446896 ITGA7 integrin subunit alpha 7 gene PW:0000286 integrin mediated signaling pathway ISO RGD:71022 W RGD:9068941 20211008 RGD PMID:1315319|REF_RGD_ID:70774 18446896 ITGA7 integrin subunit alpha 7 gene PW:0000286 integrin mediated signaling pathway ISO RGD:734343 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18447272 DUOX1 dual oxidase 1 gene PW:0002521 thyroid hormone biosynthetic pathway ISO RGD:1345114 W RGD:9068941 20211008 SMPDB SMP:00716 18447419 DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 gene PW:0000018 Parkinson's disease pathway ISO RGD:1320495 W RGD:9068941 20211008 RGD PMID:25302295|PMID:25639775|REF_RGD_ID:10450521|REF_RGD_ID:10450553 18447419 DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:1320495 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18447419 DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 gene PW:0002433 altered clathrin-dependent synaptic vesicle endocytosis ISO RGD:1320495 W RGD:9068941 20211008 RGD PMID:25302295|REF_RGD_ID:10450553 18447571 FBXO11 F-box protein 11 gene PW:0000718 p53 signaling pathway ISO RGD:1348534 W RGD:9068941 20211008 PID PID:200206 18447692 SPOP speckle type BTB/POZ protein gene PW:0000122 Hedgehog signaling pathway ISO RGD:1323163 W RGD:9068941 20211008 PID PID:200172 18447771 HJURP Holliday junction recognition protein gene PW:0001338 histone modification pathway ISO RGD:2292108 W RGD:9068941 20211008 RGD PMID:23288364|REF_RGD_ID:9068945 18447833 HNF1B HNF1 homeobox B gene PW:0000958 forkhead class A signaling pathway ISO RGD:69136 W RGD:9068941 20211008 PID PID:200087 18447968 CMAS cytidine monophosphate N-acetylneuraminic acid synthetase gene PW:0000152 amino sugar metabolic pathway ISO RGD:1322088 W RGD:9068941 20211008 SMPDB SMP:00045 18447968 CMAS cytidine monophosphate N-acetylneuraminic acid synthetase gene PW:0001631 Tay-Sachs disease pathway ISO RGD:1322088 W RGD:9068941 20211008 SMPDB SMP:00390 18447968 CMAS cytidine monophosphate N-acetylneuraminic acid synthetase gene PW:0001702 french type sialuria pathway ISO RGD:1322088 W RGD:9068941 20211008 SMPDB SMP:00216|SMP:00217 18447968 CMAS cytidine monophosphate N-acetylneuraminic acid synthetase gene PW:0002381 sialic acid storage disease pathway ISO RGD:1322088 W RGD:9068941 20211008 SMPDB SMP:00240 18447988 ATP5MC2 ATP synthase membrane subunit c locus 2 gene PW:0000034 electron transport chain pathway ISO RGD:736098 W RGD:9068941 20211008 SMPDB SMP:00355 18448130 MAP1LC3C microtubule associated protein 1 light chain 3 gamma gene PW:0000278 autophagy pathway ISO RGD:1606859 W RGD:9068941 20211008 RGD PMID:20562859|REF_RGD_ID:4890444 18448264 AP2S1 adaptor related protein complex 2 subunit sigma 1 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:732482 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18448274 FTMT ferritin mitochondrial gene PW:0000592 iron storage pathway ISO RGD:1348564 W RGD:9068941 20211008 RGD PMID:25661197|REF_RGD_ID:11554199 18448274 FTMT ferritin mitochondrial gene PW:0001785 variegate porphyria pathway ISO RGD:1348564 W RGD:9068941 20211008 SMPDB SMP:00346 18448274 FTMT ferritin mitochondrial gene PW:0001981 hereditary coproporphyria pathway ISO RGD:1348564 W RGD:9068941 20211008 SMPDB SMP:00342 18448274 FTMT ferritin mitochondrial gene PW:0002017 acute intermittent porphyria pathway ISO RGD:1348564 W RGD:9068941 20211008 SMPDB SMP:00344 18448274 FTMT ferritin mitochondrial gene PW:0002216 erythropoietic porphyria pathway ISO RGD:1348564 W RGD:9068941 20211008 SMPDB SMP:00345 18448274 FTMT ferritin mitochondrial gene PW:0002285 porphyrin metabolic pathway ISO RGD:1348564 W RGD:9068941 20211008 SMPDB SMP:00024 18448292 CD40LG CD40 ligand gene PW:0000540 obesity pathway ISO RGD:1615151 W RGD:9068941 20211008 RGD PMID:21817098|REF_RGD_ID:5490592 18448292 CD40LG CD40 ligand gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1352959 W RGD:9068941 20211008 PID PID:200022 18448399 PCYT2 phosphate cytidylyltransferase 2, ethanolamine gene PW:0001431 lamivudine pharmacokinetics pathway ISO RGD:736348 W RGD:9068941 20211008 SMPDB SMP:00649 18448607 GRK5 G protein-coupled receptor kinase 5 gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:1348499 W RGD:9068941 20211008 RGD PMID:16304060|REF_RGD_ID:5133417 18448607 GRK5 G protein-coupled receptor kinase 5 gene PW:0000794 epinephrine signaling pathway via adrenergic receptor beta ISO RGD:1348499 W RGD:9068941 20211008 RGD PMID:19110970|PMID:19229505|REF_RGD_ID:4140391|REF_RGD_ID:5135529 18448607 GRK5 G protein-coupled receptor kinase 5 gene PW:0000843 acetylcholine signaling pathway via muscarinic acetylcholine receptor ISO RGD:62277 W RGD:9068941 20211008 RGD PMID:19478075|REF_RGD_ID:8549592 18448607 GRK5 G protein-coupled receptor kinase 5 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:1348499 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18448607 GRK5 G protein-coupled receptor kinase 5 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:1348499 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18448985 CPSF7 cleavage and polyadenylation specific factor 7 gene PW:0001332 RNA polymerase II transcription termination pathway ISO RGD:1602680 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18448985 CPSF7 cleavage and polyadenylation specific factor 7 gene PW:0001579 3'-end pre-mRNA processing pathway ISO RGD:1602680 W RGD:9068941 20211008 RGD PMID:21957020|PMID:24243805|REF_RGD_ID:9681741|REF_RGD_ID:9681742 18449114 QKI QKI, KH domain containing RNA binding gene PW:0001073 spliceosome pathway ISO RGD:1319346 W RGD:9068941 20211008 RGD PMID:23385723|REF_RGD_ID:9686381 18449145 USH1C USH1 protein network component harmonin gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1604645 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18449145 USH1C USH1 protein network component harmonin gene PW:0001503 auditory mechanotransduction pathway ISO RGD:1604645 W RGD:9068941 20211008 RGD PMID:19804752|PMID:22177415|REF_RGD_ID:8547667|REF_RGD_ID:8547671 18449207 TRADD TNFRSF1A associated via death domain gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1350695 W RGD:9068941 20211008 PID PID:200102 18449207 TRADD TNFRSF1A associated via death domain gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1350695 W RGD:9068941 20211008 RGD PMID:12655295|REF_RGD_ID:2292150 18449207 TRADD TNFRSF1A associated via death domain gene PW:0000682 Trail mediated signaling pathway ISO RGD:1350695 W RGD:9068941 20211008 PID PID:200068 18449207 TRADD TNFRSF1A associated via death domain gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1350695 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18449207 TRADD TNFRSF1A associated via death domain gene PW:0000961 ceramide signaling pathway ISO RGD:1350695 W RGD:9068941 20211008 PID PID:200119 18449226 PTH parathyroid hormone gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:3440 W RGD:9068941 20211008 RGD PMID:9054374|REF_RGD_ID:7207455 18449226 PTH parathyroid hormone gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:69107 W RGD:9068941 20211008 RGD PMID:19395963|PMID:21777186|REF_RGD_ID:7207465|REF_RGD_ID:7207470 18449242 XRCC5 X-ray repair cross complementing 5 gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:733855 W RGD:9068941 20211008 RGD PMID:20192759|REF_RGD_ID:8662352 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0000052 tyrosine metabolic pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00006 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0001608 tyrosinemia type I pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00218 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0001609 tyrosinemia type II pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00369 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0001610 tyrosinemia type III pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00370 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0001805 phenylketonuria pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00206 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00429 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0002208 dopamine beta-hydroxylase deficiency pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00498 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0002277 alkaptonuria pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00169 18449296 HGD homogentisate 1,2-dioxygenase gene PW:0002380 hawkinsinuria pathway ISO RGD:1318713 W RGD:9068941 20211008 SMPDB SMP:00190 18449891 VPS35 VPS35 retromer complex component gene PW:0000018 Parkinson's disease pathway ISO RGD:1350372 W RGD:9068941 20211008 RGD PMID:25619244|PMID:25639775|PMID:25701813|PMID:26223426|REF_RGD_ID:10450518|REF_RGD_ID:10450521|REF_RGD_ID:10450542|REF_RGD_ID:10450845 18449891 VPS35 VPS35 retromer complex component gene PW:0002430 retromer-mediated pathway ISO RGD:1350372 W RGD:9068941 20211008 RGD PMID:25619244|PMID:25701813|REF_RGD_ID:10450542|REF_RGD_ID:10450845 18449891 VPS35 VPS35 retromer complex component gene PW:0002431 altered retromer-mediated pathway ISO RGD:1350372 W RGD:9068941 20211008 RGD PMID:25619244|PMID:25701813|REF_RGD_ID:10450542|REF_RGD_ID:10450845 18450074 XRCC1 X-ray repair cross complementing 1 gene PW:0000129 base excision repair pathway ISO RGD:732968 W RGD:9068941 20211008 RGD PMID:16221808|REF_RGD_ID:1578408 18450074 XRCC1 X-ray repair cross complementing 1 gene PW:0000130 nucleotide excision repair pathway ISO RGD:732968 W RGD:9068941 20211008 RGD PMID:21601536|REF_RGD_ID:7246935 18450132 SMARCD2 SWI/SNF related BAF chromatin remodeling complex subunit D2 gene PW:0001406 SWI/SNF family mediated chromatin remodeling pathway ISO RGD:734113 W RGD:9068941 20211008 RGD PMID:21358755|PMID:23355908|REF_RGD_ID:8694154|REF_RGD_ID:9495920 18450230 CHRNA5 cholinergic receptor nicotinic alpha 5 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:734445 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18450394 S100B S100 calcium binding protein B gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:737117 W RGD:9068941 20211008 RGD PMID:17964289|REF_RGD_ID:7204682 18450416 NCOA4 nuclear receptor coactivator 4 gene PW:0000590 iron homeostasis pathway ISO RGD:1348400 W RGD:9068941 20211008 RGD PMID:25661197|PMID:26725301|REF_RGD_ID:11554199|REF_RGD_ID:11556274 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0000034 electron transport chain pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00355 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0000640 glycolysis pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00040 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0000641 gluconeogenesis pathway ISO RGD:2661 W RGD:9068941 20211008 RGD PMID:15720133|REF_RGD_ID:2302795 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0000641 gluconeogenesis pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00128 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00563 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00573 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00531 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00562 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0002360 Fanconi syndrome pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00572 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00124 18450451 GAPDH glyceraldehyde-3-phosphate dehydrogenase gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:735871 W RGD:9068941 20211008 SMPDB SMP:00560 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00075 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0000462 lipoxygenase mediated pathway of arachidonic acid metabolism ISO RGD:1313295 W RGD:9068941 20211008 RGD PMID:12432922|REF_RGD_ID:1578309 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00096 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0000915 interleukin-23 signaling pathway ISO RGD:1313295 W RGD:9068941 20211008 PID PID:200154 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00086 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001524 paracetamol drug pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00710 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00083 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001665 antipyrine drug pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00692 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00116 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00704 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00706 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00094 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00077 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00120 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00114 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00106 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00109 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00098 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00085 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00084 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00289 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00093 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00696 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00104 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00104 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00700 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00709 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00708 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00353 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00705 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00697 18450464 ALOX12B arachidonate 12-lipoxygenase, 12R type gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:1313295 W RGD:9068941 20211008 SMPDB SMP:00698 18450489 PARD6B par-6 family cell polarity regulator beta gene PW:0000840 protein kinase C (PKC) signaling pathway ISO RGD:1317848 W RGD:9068941 20211008 RGD PMID:16525119|REF_RGD_ID:5132275 18450633 ITPKA inositol-trisphosphate 3-kinase A gene PW:0000046 inositol metabolic pathway ISO RGD:732603 W RGD:9068941 20211008 SMPDB SMP:00011 18450633 ITPKA inositol-trisphosphate 3-kinase A gene PW:0000154 inositol phosphate metabolic pathway ISO RGD:732603 W RGD:9068941 20211008 SMPDB SMP:00462 18450740 NUP153 nucleoporin 153 gene PW:0001587 mRNA nuclear export pathway ISO RGD:731840 W RGD:9068941 20211008 RGD PMID:25184662|REF_RGD_ID:9743947 18450783 ATG5 autophagy related 5 gene PW:0000278 autophagy pathway ISO RGD:1353398 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18450783 ATG5 autophagy related 5 gene PW:0000278 autophagy pathway ISO RGD:1359580 W RGD:9068941 20211008 RGD PMID:18059433|REF_RGD_ID:2301217 18451021 INMT indolethylamine N-methyltransferase gene PW:0000054 tryptophan metabolic pathway ISO RGD:1316407 W RGD:9068941 20211008 SMPDB SMP:00063 18451031 COQ5 coenzyme Q5, methyltransferase gene PW:0000142 ubiquinone biosynthetic pathway ISO RGD:1604266 W RGD:9068941 20211008 SMPDB SMP:00065 18451287 RPL27 ribosomal protein L27 gene PW:0000101 translation pathway ISO RGD:735597 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18451287 RPL27 ribosomal protein L27 gene PW:0001066 ribosome biogenesis pathway ISO RGD:735597 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18451354 RAB33B RAB33B, member RAS oncogene family gene PW:0000278 autophagy pathway ISO RGD:1318074 W RGD:9068941 20211008 RGD PMID:20548331|REF_RGD_ID:4892310 18451365 GTF3C6 general transcription factor IIIC subunit 6 gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1316627 W RGD:9068941 20211008 RGD PMID:23031840|REF_RGD_ID:9588284 18451403 GALK1 galactokinase 1 gene PW:0000042 galactose metabolic pathway ISO RGD:1313365 W RGD:9068941 20211008 SMPDB SMP:00043 18451403 GALK1 galactokinase 1 gene PW:0000055 nucleotide sugar metabolic pathway ISO RGD:1313365 W RGD:9068941 20211008 SMPDB SMP:00010 18451403 GALK1 galactokinase 1 gene PW:0002092 galactosemia pathway ISO RGD:1313365 W RGD:9068941 20211008 SMPDB SMP:00182 18451403 GALK1 galactokinase 1 gene PW:0002093 GALE deficiency pathway ISO RGD:1313365 W RGD:9068941 20211008 SMPDB SMP:00496 18451403 GALK1 galactokinase 1 gene PW:0002094 galactokinase deficiency pathway ISO RGD:1313365 W RGD:9068941 20211008 SMPDB SMP:00495 18451457 SUPT3H SPT3 homolog, SAGA and STAGA complex component gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1313449 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18451590 MED27 mediator complex subunit 27 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1349942 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18451617 DOT1L DOT1 like histone lysine methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1315376 W RGD:9068941 20211008 RGD PMID:12628190|PMID:22194015|REF_RGD_ID:1359080|REF_RGD_ID:7242554 18451617 DOT1L DOT1 like histone lysine methyltransferase gene PW:0001338 histone modification pathway ISO RGD:1315376 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18451713 RPL37A ribosomal protein L37a gene PW:0000101 translation pathway ISO RGD:1317728 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18451713 RPL37A ribosomal protein L37a gene PW:0001066 ribosome biogenesis pathway ISO RGD:1317728 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18451744 NUP133 nucleoporin 133 gene PW:0001587 mRNA nuclear export pathway ISO RGD:1317249 W RGD:9068941 20211008 RGD PMID:25184662|REF_RGD_ID:9743947 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0000073 lysine degradation pathway ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00037 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0000212 choline metabolic pathway ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00123 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00123 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0001703 saccharopinuria pathway ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00239|SMP:00528 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0001936 hyperlysinemia pathway ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00527 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0002204 2-aminoadipic 2-oxoadipic aciduria pathway ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00719 18451849 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene PW:0002306 glutaric aciduria type I pathway ISO RGD:1318489 W RGD:9068941 20211008 SMPDB SMP:00186 18451908 EPB41 erythrocyte membrane protein band 4.1 gene PW:0000659 syndecan signaling pathway ISO RGD:1605128 W RGD:9068941 20211008 PID PID:200192 18451981 PABPC1 poly(A) binding protein cytoplasmic 1 gene PW:0000580 translation initiation pathway ISO RGD:1349848 W RGD:9068941 20211008 RGD PMID:22815232|PMID:24499181|REF_RGD_ID:10002776|REF_RGD_ID:10044017 18451981 PABPC1 poly(A) binding protein cytoplasmic 1 gene PW:0000808 microRNA pathway ISO RGD:1349848 W RGD:9068941 20211008 RGD PMID:23337855|REF_RGD_ID:9850101 18452460 MED14 mediator complex subunit 14 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1343127 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18452460 MED14 mediator complex subunit 14 gene PW:0000569 cortisol signaling pathway ISO RGD:1343127 W RGD:9068941 20211008 RGD PMID:11306337|REF_RGD_ID:5147892 18452562 CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 gene PW:0001139 calcium transport pathway ISO RGD:68558 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18452562 CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:68558 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18452604 OAZ2 ornithine decarboxylase antizyme 2 gene PW:0000214 polyamine metabolic pathway ISO RGD:1344023 W RGD:9068941 20211008 RGD PMID:21849468|REF_RGD_ID:7244195 18452811 MAFK MAF bZIP transcription factor K gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1350091 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0001004 retinoic acid metabolic pathway ISO RGD:1352960 W RGD:9068941 20211008 RGD PMID:21621639|REF_RGD_ID:6484672 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00600 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00433 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0002132 capecitabine pharmacokinetics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00607 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0002133 capecitabine pharmacodynamics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00469 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0002508 mycophenolic acid pharmacokinetics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00652 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0002559 heroin pharmacokinetics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00623 18452878 LOC103233018 liver carboxylesterase 1 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:1352960 W RGD:9068941 20211008 SMPDB SMP:00407 18453024 SLC5A1 solute carrier family 5 member 1 gene PW:0000561 sodium-glucose cotransporter mediated glucose transport pathway ISO RGD:732146 W RGD:9068941 20211008 RGD PMID:15449578|PMID:15466941|REF_RGD_ID:1625539|REF_RGD_ID:1626159 18453024 SLC5A1 solute carrier family 5 member 1 gene PW:0001300 trehalose degradation pathway ISO RGD:732146 W RGD:9068941 20211008 SMPDB SMP:00467 18453024 SLC5A1 solute carrier family 5 member 1 gene PW:0001364 lactose degradation pathway ISO RGD:732146 W RGD:9068941 20211008 SMPDB SMP:00457 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00023 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0000728 statin pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0001586 Wolman disease pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00389 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0001812 mevalonic aciduria pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00112 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0001933 hypercholesterolemia pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00209 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00079 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002106 desmosterolosis pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00386 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00095 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00117 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00107 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00508 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00387 18453050 GGPS1 geranylgeranyl diphosphate synthase 1 gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:1343459 W RGD:9068941 20211008 SMPDB SMP:00388 18453134 CABP4 calcium binding protein 4 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1314493 W RGD:9068941 20211008 RGD PMID:20668007|REF_RGD_ID:7204681 18453225 GNAZ G protein subunit alpha z gene PW:0000122 Hedgehog signaling pathway ISO RGD:733341 W RGD:9068941 20211008 PID PID:200172 18453225 GNAZ G protein subunit alpha z gene PW:0000506 endothelin signaling pathway ISO RGD:733341 W RGD:9068941 20211008 PID PID:200005 18453225 GNAZ G protein subunit alpha z gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:733341 W RGD:9068941 20211008 PID PID:200046|PID:200054|PID:200076|PID:200085|PID:200123|PID:200211 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0000064 propanoate metabolic pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00016 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00032 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001778 propionic acidemia pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00236 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00384 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001810 methylmalonic acidemia pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00200 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001811 methylmalonic aciduria, cobalamin-related pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00201 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001870 maple syrup urine disease pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00199 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001874 isovaleric acidemia pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00523 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00139 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00140 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0002289 malonic aciduria pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00198|SMP:00502 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00138 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18453300 PCCB propionyl-CoA carboxylase subunit beta gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:731965 W RGD:9068941 20211008 SMPDB SMP:00237 18453486 CHRNA2 cholinergic receptor nicotinic alpha 2 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:735907 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18453518 CASP5 caspase 5 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1351672 W RGD:9068941 20211008 RGD PMID:20303873|REF_RGD_ID:5490211 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0000043 pyruvate metabolic pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00060 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0000049 cysteine metabolic pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00013 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0000641 gluconeogenesis pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00128 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001416 Leigh disease pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00196 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00563 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00559 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00212 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00334 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00558 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00573 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00562 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0002218 ocular nonnephropathic cystinosis pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00722 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0002568 mercaptolactate-cysteine disulfiduria pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00499 18453578 LDHAL6A lactate dehydrogenase A like 6A gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:1345599 W RGD:9068941 20211008 SMPDB SMP:00560 18453596 ERC1 ELKS/RAB6-interacting/CAST family member 1 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1604628 W RGD:9068941 20211008 PID PID:200031 18453596 ERC1 ELKS/RAB6-interacting/CAST family member 1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1604628 W RGD:9068941 20211008 PID PID:200089 18453710 MYD88 MYD88 innate immune signal transduction adaptor gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1345144 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18453710 MYD88 MYD88 innate immune signal transduction adaptor gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1345144 W RGD:9068941 20211008 PID PID:200089 18453710 MYD88 MYD88 innate immune signal transduction adaptor gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1345144 W RGD:9068941 20211008 RGD PMID:18535784|PMID:20086235|REF_RGD_ID:5490215|REF_RGD_ID:5490218 18453719 SLC7A2 solute carrier family 7 member 2 gene PW:0000073 lysine degradation pathway ISO RGD:68562 W RGD:9068941 20211008 SMPDB SMP:00037 18453719 SLC7A2 solute carrier family 7 member 2 gene PW:0001703 saccharopinuria pathway ISO RGD:68562 W RGD:9068941 20211008 SMPDB SMP:00239|SMP:00528 18453719 SLC7A2 solute carrier family 7 member 2 gene PW:0001936 hyperlysinemia pathway ISO RGD:68562 W RGD:9068941 20211008 SMPDB SMP:00527 18453719 SLC7A2 solute carrier family 7 member 2 gene PW:0002204 2-aminoadipic 2-oxoadipic aciduria pathway ISO RGD:68562 W RGD:9068941 20211008 SMPDB SMP:00719 18453719 SLC7A2 solute carrier family 7 member 2 gene PW:0002306 glutaric aciduria type I pathway ISO RGD:68562 W RGD:9068941 20211008 SMPDB SMP:00186 18453907 GNAQ G protein subunit alpha q gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:620770 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18453907 GNAQ G protein subunit alpha q gene PW:0000229 G protein mediated signaling pathway via Galphaq family ISO RGD:731425 W RGD:9068941 20211008 RGD PMID:11395409|PMID:14624682|PMID:23759942|REF_RGD_ID:1579891|REF_RGD_ID:5131495|REF_RGD_ID:8549590 18453907 GNAQ G protein subunit alpha q gene PW:0000491 vasopressin signaling pathway ISO RGD:731425 W RGD:9068941 20211008 RGD PMID:14624682|REF_RGD_ID:1579891 18453907 GNAQ G protein subunit alpha q gene PW:0000494 oxytocin signaling pathway ISO RGD:731425 W RGD:9068941 20211008 RGD PMID:14624682|REF_RGD_ID:1579891 18453907 GNAQ G protein subunit alpha q gene PW:0000506 endothelin signaling pathway ISO RGD:731425 W RGD:9068941 20211008 PID PID:200005 18453907 GNAQ G protein subunit alpha q gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:731425 W RGD:9068941 20211008 RGD PMID:16141358|REF_RGD_ID:1581847 18453907 GNAQ G protein subunit alpha q gene PW:0000565 eicosanoid signaling pathway ISO RGD:731425 W RGD:9068941 20211008 PID PID:200082 18453907 GNAQ G protein subunit alpha q gene PW:0000585 orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1 ISO RGD:620770 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18453907 GNAQ G protein subunit alpha q gene PW:0000586 orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2 ISO RGD:620770 W RGD:9068941 20211008 RGD PMID:12890892|REF_RGD_ID:1642020 18453907 GNAQ G protein subunit alpha q gene PW:0000712 vasopressin signaling pathway via receptor type 1 ISO RGD:731425 W RGD:9068941 20211008 RGD PMID:14624682|REF_RGD_ID:1579891 18453907 GNAQ G protein subunit alpha q gene PW:0000855 acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family ISO RGD:731425 W RGD:9068941 20211008 RGD PMID:23759942|REF_RGD_ID:8549590 18453907 GNAQ G protein subunit alpha q gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:731425 W RGD:9068941 20211008 PID PID:200046|PID:200123|PID:200211 18453935 GJC1 gap junction protein gamma 1 gene PW:0000334 connexin signaling pathway ISO RGD:1350984 W RGD:9068941 20211008 RGD PMID:15381756|REF_RGD_ID:1580398 18453945 PARP15 poly(ADP-ribose) polymerase family member 15 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1353381 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18454042 RICTOR RPTOR independent companion of MTOR complex 2 gene PW:0000180 mTOR signaling pathway ISO RGD:1307224 W RGD:9068941 20211008 RGD PMID:17110594|REF_RGD_ID:2307383 18454042 RICTOR RPTOR independent companion of MTOR complex 2 gene PW:0000180 mTOR signaling pathway ISO RGD:1604194 W RGD:9068941 20211008 PID PID:200096 18454042 RICTOR RPTOR independent companion of MTOR complex 2 gene PW:0000180 mTOR signaling pathway ISO RGD:1604194 W RGD:9068941 20211008 RGD PMID:16885148|PMID:19339977|PMID:22500797|REF_RGD_ID:11535033|REF_RGD_ID:1625616|REF_RGD_ID:2308795 18454042 RICTOR RPTOR independent companion of MTOR complex 2 gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:1604194 W RGD:9068941 20211008 PID PID:200197 18454433 EBP EBP cholestenol delta-isomerase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:1345811 W RGD:9068941 20211008 RGD PMID:12668600|PMID:16876788|REF_RGD_ID:2316857|REF_RGD_ID:2316868 18454433 EBP EBP cholestenol delta-isomerase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00023 18454433 EBP EBP cholestenol delta-isomerase gene PW:0000728 statin pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18454433 EBP EBP cholestenol delta-isomerase gene PW:0001586 Wolman disease pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18454433 EBP EBP cholestenol delta-isomerase gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18454433 EBP EBP cholestenol delta-isomerase gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00389 18454433 EBP EBP cholestenol delta-isomerase gene PW:0001812 mevalonic aciduria pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18454433 EBP EBP cholestenol delta-isomerase gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00112 18454433 EBP EBP cholestenol delta-isomerase gene PW:0001933 hypercholesterolemia pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00209 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00079 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002106 desmosterolosis pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00386 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00095 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00117 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00107 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00508 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00387 18454433 EBP EBP cholestenol delta-isomerase gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:1345811 W RGD:9068941 20211008 SMPDB SMP:00388 18454451 SLC24A5 solute carrier family 24 member 5 gene PW:0001139 calcium transport pathway ISO RGD:1321543 W RGD:9068941 20211008 RGD PMID:17716241|REF_RGD_ID:7204698 18454451 SLC24A5 solute carrier family 24 member 5 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1321543 W RGD:9068941 20211008 RGD PMID:17716241|REF_RGD_ID:7204698 18454478 SIAH2 siah E3 ubiquitin protein ligase 2 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:734303 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18454478 SIAH2 siah E3 ubiquitin protein ligase 2 gene PW:0000507 estrogen signaling pathway ISO RGD:734303 W RGD:9068941 20211008 RGD PMID:16394250|REF_RGD_ID:5128512 18454723 MYCBP MYC binding protein gene PW:0000204 Notch signaling pathway ISO RGD:1315945 W RGD:9068941 20211008 PID PID:200015 18454791 ADAM12 ADAM metallopeptidase domain 12 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1317265 W RGD:9068941 20211008 RGD PMID:15688065|REF_RGD_ID:2317976 18454791 ADAM12 ADAM metallopeptidase domain 12 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1317266 W RGD:9068941 20211008 RGD PMID:15688065|REF_RGD_ID:2317976 18454791 ADAM12 ADAM metallopeptidase domain 12 gene PW:0000204 Notch signaling pathway ISO RGD:1317265 W RGD:9068941 20211008 PID PID:200015 18454791 ADAM12 ADAM metallopeptidase domain 12 gene PW:0000659 syndecan signaling pathway ISO RGD:1317265 W RGD:9068941 20211008 PID PID:200134 18455059 ALDOB aldolase, fructose-bisphosphate B gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:737371 W RGD:9068941 20211008 SMPDB SMP:00064 18455059 ALDOB aldolase, fructose-bisphosphate B gene PW:0000640 glycolysis pathway ISO RGD:737371 W RGD:9068941 20211008 RGD PMID:5251864|REF_RGD_ID:2302796 18455059 ALDOB aldolase, fructose-bisphosphate B gene PW:0000641 gluconeogenesis pathway ISO RGD:737371 W RGD:9068941 20211008 RGD PMID:5251864|REF_RGD_ID:2302796 18455059 ALDOB aldolase, fructose-bisphosphate B gene PW:0000958 forkhead class A signaling pathway ISO RGD:737371 W RGD:9068941 20211008 PID PID:200087 18455059 ALDOB aldolase, fructose-bisphosphate B gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:737371 W RGD:9068941 20211008 SMPDB SMP:00725 18455059 ALDOB aldolase, fructose-bisphosphate B gene PW:0002388 fructosuria pathway ISO RGD:737371 W RGD:9068941 20211008 SMPDB SMP:00561 18455075 DAGLA diacylglycerol lipase alpha gene PW:0000993 N-cadherin signaling pathway ISO RGD:1343376 W RGD:9068941 20211008 PID PID:200209 18455124 MAPK12 mitogen-activated protein kinase 12 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:731716 W RGD:9068941 20211008 RGD PMID:17481747|REF_RGD_ID:2293891 18455155 CDK7 cyclin dependent kinase 7 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:734279 W RGD:9068941 20211008 RGD pol II carboxyl-terminal domain (CTD) PMID:22622228|PMID:23837720|REF_RGD_ID:9681737|REF_RGD_ID:9681738 18455155 CDK7 cyclin dependent kinase 7 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:734279 W RGD:9068941 20211008 RGD PMID:21592869|REF_RGD_ID:9681726 18455234 HDC histidine decarboxylase gene PW:0000051 histidine metabolic pathway ISO RGD:736253 W RGD:9068941 20211008 SMPDB SMP:00044 18455234 HDC histidine decarboxylase gene PW:0001978 histidinemia pathway ISO RGD:736253 W RGD:9068941 20211008 SMPDB SMP:00191 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00296 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001139 calcium transport pathway ISO RGD:68989 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:68989 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00379 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00665 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00376 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00375 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00659 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00660 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00323 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00307 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00324 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00380 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00381 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00382 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00366 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00302 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00378 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00332 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00331 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00301 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00325 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00359 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002134 bupranolol drug pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00670 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00670 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00300 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00299 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00296 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00298 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00305 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00303 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00306 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00326 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00666 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00327 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00329 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00662 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00663 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00328 18455312 CACNA1G calcium voltage-gated channel subunit alpha1 G gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:68989 W RGD:9068941 20211008 SMPDB SMP:00367 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00296 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001139 calcium transport pathway ISO RGD:732978 W RGD:9068941 20211008 RGD PMID:19133301|REF_RGD_ID:7204693 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:732978 W RGD:9068941 20211008 RGD PMID:19133301|REF_RGD_ID:7204693 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00379 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00665 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00376 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00375 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00659 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00660 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00323 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00307 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00324 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00380 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00381 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00382 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00366 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00302 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00378 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00332 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00331 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00301 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00325 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00359 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002134 bupranolol drug pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00670 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00670 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00300 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00299 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00296 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00298 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00305 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00303 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00306 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00326 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00666 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00327 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00329 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00662 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00663 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00328 18455527 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:732978 W RGD:9068941 20211008 SMPDB SMP:00367 18455618 PRCP prolylcarboxypeptidase gene PW:0000526 kallikrein-kinin cascade pathway ISO RGD:1317272 W RGD:9068941 20211008 RGD PMID:18396440|REF_RGD_ID:7401224 18455641 YBX1 Y-box binding protein 1 gene PW:0000718 p53 signaling pathway ISO RGD:732883 W RGD:9068941 20211008 RGD PMID:20679336|REF_RGD_ID:8662965 18455641 YBX1 Y-box binding protein 1 gene PW:0001508 cisplatin drug pathway ISO RGD:732883 W RGD:9068941 20211008 RGD PMID:20046924|REF_RGD_ID:8548475 18455762 AVP arginine vasopressin gene PW:0000491 vasopressin signaling pathway ISO RGD:2184 W RGD:9068941 20211008 RGD PMID:12942143|PMID:18299204|PMID:18431594|REF_RGD_ID:1358326|REF_RGD_ID:2301920|REF_RGD_ID:2312656 18455762 AVP arginine vasopressin gene PW:0000491 vasopressin signaling pathway ISO RGD:68968 W RGD:9068941 20211008 RGD PMID:14624682|PMID:18431594|REF_RGD_ID:1579891|REF_RGD_ID:2312656 18455762 AVP arginine vasopressin gene PW:0000712 vasopressin signaling pathway via receptor type 1 ISO RGD:68968 W RGD:9068941 20211008 RGD PMID:14624682|REF_RGD_ID:1579891 18455762 AVP arginine vasopressin gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:2184 W RGD:9068941 20211008 RGD PMID:18431594|REF_RGD_ID:2312656 18455762 AVP arginine vasopressin gene PW:0000713 vasopressin signaling pathway via receptor type 2 ISO RGD:68968 W RGD:9068941 20211008 RGD PMID:14624682|PMID:18431594|REF_RGD_ID:1579891|REF_RGD_ID:2312656 18455862 ADORA2A adenosine A2a receptor gene PW:0000360 hypoxia inducible factor pathway ISO RGD:730999 W RGD:9068941 20211008 PID PID:200036 18455862 ADORA2A adenosine A2a receptor gene PW:0000998 adenosine signaling pathway ISO RGD:730999 W RGD:9068941 20211008 SMPDB SMP:00320 18456184 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:1602218 W RGD:9068941 20211008 RGD PMID:21070840|PMID:21301225|REF_RGD_ID:7240706|REF_RGD_ID:7240707 18456431 TOMM70 translocase of outer mitochondrial membrane 70 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1343038 W RGD:9068941 20211008 RGD PMID:25542066|PMID:25633533|REF_RGD_ID:10412658|REF_RGD_ID:10412659 18456431 TOMM70 translocase of outer mitochondrial membrane 70 gene PW:0002138 carrier pathway of mitochondrial protein import ISO RGD:1343038 W RGD:9068941 20211008 RGD PMID:25980382|REF_RGD_ID:10412661 18456431 TOMM70 translocase of outer mitochondrial membrane 70 gene PW:0002140 beta-barrel pathway of mitochondrial protein import ISO RGD:1343038 W RGD:9068941 20211008 RGD PMID:25305573|REF_RGD_ID:10412662 18456431 TOMM70 translocase of outer mitochondrial membrane 70 gene PW:0002141 alpha-helical insertion pathway of mitochondrial protein import ISO RGD:1343038 W RGD:9068941 20211008 RGD PMID:25633533|REF_RGD_ID:10412658 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000560 facilitative sugar transporter mediated glucose transport pathway ISO RGD:730861 W RGD:9068941 20211008 RGD PMID:15449578|REF_RGD_ID:1626159 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000640 glycolysis pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00040 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000641 gluconeogenesis pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00128 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000674 insulin secretion pathway ISO RGD:11306 W RGD:9068941 20211008 RGD PMID:18774732|REF_RGD_ID:2311061 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000674 insulin secretion pathway ISO RGD:3705 W RGD:9068941 20211008 RGD PMID:18774732|REF_RGD_ID:2311061 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000674 insulin secretion pathway ISO RGD:730861 W RGD:9068941 20211008 RGD PMID:18774732|REF_RGD_ID:2311061 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000725 potassium channel inhibitors pharmacodynamics pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00453|SMP:00454 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0000958 forkhead class A signaling pathway ISO RGD:730861 W RGD:9068941 20211008 PID PID:200087 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0001300 trehalose degradation pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00467 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0001364 lactose degradation pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00457 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00563 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00573 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0001997 glycogen storage disease type VII pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00531 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0002008 gliclazide pharmacodynamics pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00461 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0002011 glyburide pharmacodynamics pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00460 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00562 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0002360 Fanconi syndrome pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00572 18456447 SLC2A2 solute carrier family 2 member 2 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:730861 W RGD:9068941 20211008 SMPDB SMP:00560 18456478 MSRB2 methionine sulfoxide reductase B2 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1345900 W RGD:9068941 20211008 SMPDB SMP:00033 18456478 MSRB2 methionine sulfoxide reductase B2 gene PW:0001841 homocystinuria pathway ISO RGD:1345900 W RGD:9068941 20211008 SMPDB SMP:00177 18456478 MSRB2 methionine sulfoxide reductase B2 gene PW:0001868 hypermethioninemia pathway ISO RGD:1345900 W RGD:9068941 20211008 SMPDB SMP:00221 18456478 MSRB2 methionine sulfoxide reductase B2 gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:1345900 W RGD:9068941 20211008 SMPDB SMP:00222 18456478 MSRB2 methionine sulfoxide reductase B2 gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:1345900 W RGD:9068941 20211008 SMPDB SMP:00340 18456478 MSRB2 methionine sulfoxide reductase B2 gene PW:0002471 hypermethioninemia pathway ISO RGD:1345900 W RGD:9068941 20211008 SMPDB SMP:00341 18456493 DLC1 DLC1 Rho GTPase activating protein gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:68416 W RGD:9068941 20211008 RGD PMID:7835339|REF_RGD_ID:68218 18456518 KDM1B lysine demethylase 1B gene PW:0001338 histone modification pathway ISO RGD:1321760 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18456548 DDB1 damage specific DNA binding protein 1 gene PW:0000130 nucleotide excision repair pathway ISO RGD:734016 W RGD:9068941 20211008 RGD PMID:22572993|REF_RGD_ID:7246920 18456548 DDB1 damage specific DNA binding protein 1 gene PW:0001359 altered nucleotide excision repair pathway ISO RGD:734016 W RGD:9068941 20211008 RGD PMID:22824526|REF_RGD_ID:7246919 18456597 KEAP1 kelch like ECH associated protein 1 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1605110 W RGD:9068941 20211008 RGD PMID:24647116|PMID:26419687|REF_RGD_ID:11530066|REF_RGD_ID:11535066 18456597 KEAP1 kelch like ECH associated protein 1 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:621619 W RGD:9068941 20241031 RGD PMID:20026152|REF_RGD_ID:6902900 18456755 PHC1 polyhomeotic homolog 1 gene PW:0001338 histone modification pathway ISO RGD:1319414 W RGD:9068941 20211008 RGD PMID:23473600|PMID:25065329|REF_RGD_ID:9479058|REF_RGD_ID:9479060 18456791 IL12RB2 interleukin 12 receptor subunit beta 2 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1346577 W RGD:9068941 20211008 PID PID:200045 18456791 IL12RB2 interleukin 12 receptor subunit beta 2 gene PW:0000916 interleukin-27 signaling pathway ISO RGD:1346577 W RGD:9068941 20211008 PID PID:200028 18456849 PCGF6 polycomb group ring finger 6 gene PW:0001338 histone modification pathway ISO RGD:1353848 W RGD:9068941 20211008 RGD PMID:23473600|PMID:25065329|REF_RGD_ID:9479058|REF_RGD_ID:9479060 18456927 ARPC3 actin related protein 2/3 complex subunit 3 gene PW:0000159 Rab family mediated signaling pathway ISO RGD:1323728 W RGD:9068941 20211008 RGD PMID:20739464|REF_RGD_ID:10054052 18456927 ARPC3 actin related protein 2/3 complex subunit 3 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1323728 W RGD:9068941 20211008 PID PID:200149 18456927 ARPC3 actin related protein 2/3 complex subunit 3 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1323728 W RGD:9068941 20211008 RGD PMID:20739464|REF_RGD_ID:10054052 18456952 ARHGEF7 Rho guanine nucleotide exchange factor 7 gene PW:0000998 adenosine signaling pathway ISO RGD:736143 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18457099 LOC103242911 nucleoside diphosphate kinase B gene PW:0000862 de novo pyrimidine biosynthetic pathway ISO RGD:1346564 W RGD:9068941 20211008 RGD PMID:11768308|REF_RGD_ID:5134680 18457099 LOC103242911 nucleoside diphosphate kinase B gene PW:0001617 adefovir pharmacokinetics pathway ISO RGD:1346564 W RGD:9068941 20211008 SMPDB SMP:00629 18457099 LOC103242911 nucleoside diphosphate kinase B gene PW:0001772 tenofovir pharmacokinetics pathway ISO RGD:1346564 W RGD:9068941 20211008 SMPDB SMP:00630 18457099 LOC103242911 nucleoside diphosphate kinase B gene PW:0002072 lactose biosynthetic pathway ISO RGD:1346564 W RGD:9068941 20211008 SMPDB SMP:00444 18457099 LOC103242911 nucleoside diphosphate kinase B gene PW:0002467 Glut1 deficiency syndrome pathway ISO RGD:1346564 W RGD:9068941 20211008 SMPDB SMP:00580 18457354 CAPN1 calpain 1 gene PW:0000183 the proteolytic pathway involving calcium-dependent proteases ISO RGD:2267 W RGD:9068941 20211008 RGD PMID:17429681|REF_RGD_ID:1626249 18457567 RAB13 RAB13, member RAS oncogene family gene PW:0000159 Rab family mediated signaling pathway ISO RGD:620880 W RGD:9068941 20211008 RGD PMID:24598362|REF_RGD_ID:10053653 18457567 RAB13 RAB13, member RAS oncogene family gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:620880 W RGD:9068941 20211008 RGD PMID:24598362|REF_RGD_ID:10053653 18457580 SYF2 SYF2 pre-mRNA splicing factor gene PW:0001073 spliceosome pathway ISO RGD:1603674 W RGD:9068941 20211008 RGD PMID:23742842|REF_RGD_ID:9686094 18457741 LOC103233229 cadherin-1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:737413 W RGD:9068941 20211008 PID PID:200220 18457741 LOC103233229 cadherin-1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:737413 W RGD:9068941 20211008 PID PID:200124|PID:200147|PID:200182 18457761 AKAP11 A-kinase anchoring protein 11 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:2079 W RGD:9068941 20211008 RGD PMID:18385542|REF_RGD_ID:2312637 18457761 AKAP11 A-kinase anchoring protein 11 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:736276 W RGD:9068941 20211008 RGD PMID:14715913|PMID:19319965|REF_RGD_ID:2312475|REF_RGD_ID:2312477 18457987 NUP98 nucleoporin 98 and 96 precursor gene PW:0001587 mRNA nuclear export pathway ISO RGD:733793 W RGD:9068941 20211008 RGD PMID:25184662|REF_RGD_ID:9743947 18457987 NUP98 nucleoporin 98 and 96 precursor gene PW:0001626 CRM1 export pathway ISO RGD:733793 W RGD:9068941 20211008 RGD PMID:23583578|REF_RGD_ID:9743967 18458245 EIF3M eukaryotic translation initiation factor 3 subunit M gene PW:0000580 translation initiation pathway ISO RGD:1607072 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18458262 IMMP1L inner mitochondrial membrane peptidase subunit 1 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1601711 W RGD:9068941 20211008 RGD PMID:22172993|REF_RGD_ID:10412669 18458375 MMP7 matrix metallopeptidase 7 gene PW:0000659 syndecan signaling pathway ISO RGD:736005 W RGD:9068941 20211008 PID PID:200156 18458438 BMS1 BMS1 ribosome biogenesis factor gene PW:0001066 ribosome biogenesis pathway ISO RGD:1345685 W RGD:9068941 20211008 RGD PMID:24550520|REF_RGD_ID:9999445 18458645 RPL30 ribosomal protein L30 gene PW:0000101 translation pathway ISO RGD:731558 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18458645 RPL30 ribosomal protein L30 gene PW:0001066 ribosome biogenesis pathway ISO RGD:731558 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18458733 PLB1 phospholipase B1 gene PW:0000141 retinol metabolic pathway ISO RGD:1346755 W RGD:9068941 20211008 RGD PMID:21718801|REF_RGD_ID:6484679 18458733 PLB1 phospholipase B1 gene PW:0000141 retinol metabolic pathway ISO RGD:621565 W RGD:9068941 20211008 RGD PMID:21718801|PMID:8117729|REF_RGD_ID:6484679|REF_RGD_ID:6903951 18458863 ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 gene PW:0001139 calcium transport pathway ISO RGD:731640 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18458863 ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:731640 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18458895 EPAS1 endothelial PAS domain protein 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:68594 W RGD:9068941 20211008 PID PID:200036 18458895 EPAS1 endothelial PAS domain protein 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:68594 W RGD:9068941 20211008 RGD PMID:20396958|PMID:22169972|REF_RGD_ID:6483352|REF_RGD_ID:6483503 18459082 F2RL2 coagulation factor II thrombin receptor like 2 gene PW:0000143 insulin signaling pathway ISO RGD:1348825 W RGD:9068941 20211008 PID PID:200014 18459082 F2RL2 coagulation factor II thrombin receptor like 2 gene PW:0002610 protease mediated signaling via protease-activated receptor 3 ISO RGD:1348825 W RGD:9068941 20211008 RGD PMID:27126649|REF_RGD_ID:11352286 18459173 STK36 serine/threonine kinase 36 gene PW:0000122 Hedgehog signaling pathway ISO RGD:1316442 W RGD:9068941 20211008 PID PID:200172 18459335 FGF9 fibroblast growth factor 9 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:2610 W RGD:9068941 20211008 RGD PMID:15231666|REF_RGD_ID:1304345 18459335 FGF9 fibroblast growth factor 9 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:735806 W RGD:9068941 20211008 PID PID:200220 18459425 AP1B1 adaptor related protein complex 1 subunit beta 1 gene PW:0000958 forkhead class A signaling pathway ISO RGD:1350470 W RGD:9068941 20211008 PID PID:200226 18459491 RPL38 ribosomal protein L38 gene PW:0000101 translation pathway ISO RGD:1313682 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18459491 RPL38 ribosomal protein L38 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1313682 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18459654 GPC5 glypican 5 gene PW:0000122 Hedgehog signaling pathway ISO RGD:1318835 W RGD:9068941 20211008 RGD PMID:20231458|REF_RGD_ID:5510027 18459829 SNRNP200 small nuclear ribonucleoprotein U5 subunit 200 gene PW:0001073 spliceosome pathway ISO RGD:1351534 W RGD:9068941 20211008 RGD PMID:23454554|PMID:23592432|REF_RGD_ID:9686090|REF_RGD_ID:9686093 18460077 ERCC4 ERCC excision repair 4, endonuclease catalytic subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1312517 W RGD:9068941 20211008 RGD PMID:19154342|REF_RGD_ID:7246926 18460077 ERCC4 ERCC excision repair 4, endonuclease catalytic subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1312517 W RGD:9068941 20211008 SMPDB SMP:00478 18460077 ERCC4 ERCC excision repair 4, endonuclease catalytic subunit gene PW:0001359 altered nucleotide excision repair pathway ISO RGD:1312517 W RGD:9068941 20211008 RGD PMID:22824526|REF_RGD_ID:7246919 18460077 ERCC4 ERCC excision repair 4, endonuclease catalytic subunit gene PW:0001359 altered nucleotide excision repair pathway ISO RGD:1312517 W RGD:9068941 20211008 RGD in silico assessment of alteration of DNA-protein, protein-protein interactions and observed reduction of DNA repair capacity in the context of nucleotide excision repair pathway for SNP PMID:24004570|REF_RGD_ID:9588971 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0000039 bile acid biosynthetic pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00035 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00130 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0001415 Zellweger syndrome pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00316 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00315 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0001479 lipoid congenital adrenal hyperplasia pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00371 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0002166 17-alpha-hydroxylase deficiency pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00372 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0002167 21-alpha-hydroxylase deficiency pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00373 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0002168 11-beta-hydroxylase deficiency pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00575 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0002302 familial hypercholanemia pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00317 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0002466 apparent mineralocorticoid excess syndrome pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00717 18460132 AKR1D1 aldo-keto reductase family 1 member D1 gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:736637 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18460153 PPP1R3B protein phosphatase 1 regulatory subunit 3B gene PW:0000532 glycogen biosynthetic pathway ISO RGD:1344962 W RGD:9068941 20211008 RGD PMID:14715909|REF_RGD_ID:2304325 18460153 PPP1R3B protein phosphatase 1 regulatory subunit 3B gene PW:0000532 glycogen biosynthetic pathway ISO RGD:621600 W RGD:9068941 20211008 RGD PMID:11716774|PMID:7720853|REF_RGD_ID:2304267|REF_RGD_ID:2306167 18460153 PPP1R3B protein phosphatase 1 regulatory subunit 3B gene PW:0000534 glycogen degradation pathway ISO RGD:1344962 W RGD:9068941 20211008 RGD PMID:14715909|REF_RGD_ID:2304325 18460153 PPP1R3B protein phosphatase 1 regulatory subunit 3B gene PW:0000534 glycogen degradation pathway ISO RGD:621600 W RGD:9068941 20211008 RGD PMID:11716774|PMID:7720853|REF_RGD_ID:2304267|REF_RGD_ID:2306167 18460162 SST somatostatin gene PW:0000579 somatostatin signaling pathway ISO RGD:3761 W RGD:9068941 20211008 RGD PMID:17021051|REF_RGD_ID:1641809 18460162 SST somatostatin gene PW:0000579 somatostatin signaling pathway ISO RGD:734231 W RGD:9068941 20211008 RGD PMID:17021051|REF_RGD_ID:1641809 18460162 SST somatostatin gene PW:0000579 somatostatin signaling pathway ISO RGD:737256 W RGD:9068941 20211008 RGD PMID:17021051|REF_RGD_ID:1641809 18460162 SST somatostatin gene PW:0000769 omeprazole pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00226 18460162 SST somatostatin gene PW:0001836 roxatidine acetate pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00734 18460162 SST somatostatin gene PW:0001845 ranitidine pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00230 18460162 SST somatostatin gene PW:0001848 rabeprazole pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00229 18460162 SST somatostatin gene PW:0001884 pirenzepine pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00246 18460162 SST somatostatin gene PW:0001890 pantoprazole pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00228 18460162 SST somatostatin gene PW:0001906 nizatidine pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00233 18460162 SST somatostatin gene PW:0001965 lansoprazole pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00227 18460162 SST somatostatin gene PW:0002039 famotidine pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00231 18460162 SST somatostatin gene PW:0002112 cimetidine pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00232 18460162 SST somatostatin gene PW:0002184 esomeprazole pharmacodynamics pathway ISO RGD:734231 W RGD:9068941 20211008 SMPDB SMP:00225 18460210 PELI2 pellino E3 ubiquitin protein ligase family member 2 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1353013 W RGD:9068941 20211008 RGD PMID:20086235|REF_RGD_ID:5490215 18460319 TPM1 tropomyosin 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00296 18460319 TPM1 tropomyosin 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00379 18460319 TPM1 tropomyosin 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00665 18460319 TPM1 tropomyosin 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00376 18460319 TPM1 tropomyosin 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00375 18460319 TPM1 tropomyosin 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00659 18460319 TPM1 tropomyosin 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00660 18460319 TPM1 tropomyosin 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00323 18460319 TPM1 tropomyosin 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00307 18460319 TPM1 tropomyosin 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00324 18460319 TPM1 tropomyosin 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00380 18460319 TPM1 tropomyosin 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00381 18460319 TPM1 tropomyosin 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00382 18460319 TPM1 tropomyosin 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00366 18460319 TPM1 tropomyosin 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00302 18460319 TPM1 tropomyosin 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00378 18460319 TPM1 tropomyosin 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00332 18460319 TPM1 tropomyosin 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00331 18460319 TPM1 tropomyosin 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00301 18460319 TPM1 tropomyosin 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00325 18460319 TPM1 tropomyosin 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00359 18460319 TPM1 tropomyosin 1 gene PW:0002134 bupranolol drug pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00670 18460319 TPM1 tropomyosin 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00670 18460319 TPM1 tropomyosin 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00300 18460319 TPM1 tropomyosin 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00299 18460319 TPM1 tropomyosin 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00296 18460319 TPM1 tropomyosin 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00298 18460319 TPM1 tropomyosin 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00305 18460319 TPM1 tropomyosin 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00303 18460319 TPM1 tropomyosin 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00306 18460319 TPM1 tropomyosin 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00326 18460319 TPM1 tropomyosin 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00666 18460319 TPM1 tropomyosin 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00327 18460319 TPM1 tropomyosin 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00329 18460319 TPM1 tropomyosin 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00662 18460319 TPM1 tropomyosin 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00663 18460319 TPM1 tropomyosin 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00328 18460319 TPM1 tropomyosin 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:737098 W RGD:9068941 20211008 SMPDB SMP:00367 18460431 AKAP1 A-kinase anchoring protein 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1343676 W RGD:9068941 20211008 PID PID:200188 18460431 AKAP1 A-kinase anchoring protein 1 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1343676 W RGD:9068941 20211008 RGD PMID:14715913|PMID:19319965|REF_RGD_ID:2312475|REF_RGD_ID:2312477 18460546 GYS2 glycogen synthase 2 gene PW:0000151 starch and sucrose metabolic pathway ISO RGD:733991 W RGD:9068941 20211008 SMPDB SMP:00058 18460546 GYS2 glycogen synthase 2 gene PW:0000532 glycogen biosynthetic pathway ISO RGD:2773 W RGD:9068941 20211008 RGD PMID:15138155|PMID:6449198|REF_RGD_ID:1582633|REF_RGD_ID:1642743 18460546 GYS2 glycogen synthase 2 gene PW:0000532 glycogen biosynthetic pathway ISO RGD:733991 W RGD:9068941 20211008 RGD PMID:12297270|REF_RGD_ID:2304106 18460546 GYS2 glycogen synthase 2 gene PW:0000533 glycogen metabolic pathway ISO RGD:2773 W RGD:9068941 20211008 RGD PMID:15138155|REF_RGD_ID:1582633 18460546 GYS2 glycogen synthase 2 gene PW:0001648 congenital sucrase-isomaltase deficiency pathway ISO RGD:733991 W RGD:9068941 20211008 SMPDB SMP:00557 18460546 GYS2 glycogen synthase 2 gene PW:0001994 glycogen storage disease type III pathway ISO RGD:733991 W RGD:9068941 20211008 SMPDB SMP:00553 18460546 GYS2 glycogen synthase 2 gene PW:0001995 glycogen storage disease type IV pathway ISO RGD:733991 W RGD:9068941 20211008 SMPDB SMP:00554 18460546 GYS2 glycogen synthase 2 gene PW:0001996 glycogen storage disease type VI pathway ISO RGD:733991 W RGD:9068941 20211008 SMPDB SMP:00555 18460567 FST follistatin gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:734008 W RGD:9068941 20211008 PID PID:200144 18460628 ADCY1 adenylate cyclase 1 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:1319601 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18460628 ADCY1 adenylate cyclase 1 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:1319602 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18460628 ADCY1 adenylate cyclase 1 gene PW:0000506 endothelin signaling pathway ISO RGD:1319601 W RGD:9068941 20211008 PID PID:200005 18460628 ADCY1 adenylate cyclase 1 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1319601 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18460628 ADCY1 adenylate cyclase 1 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1319602 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18460724 SNAP91 synaptosome associated protein 91 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:731271 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18460806 EIF4H eukaryotic translation initiation factor 4H gene PW:0000580 translation initiation pathway ISO RGD:1347903 W RGD:9068941 20211008 RGD PMID:21427765|REF_RGD_ID:10044021 18460876 PMM1 phosphomannomutase 1 gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:1322064 W RGD:9068941 20211008 SMPDB SMP:00064 18460876 PMM1 phosphomannomutase 1 gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:1322064 W RGD:9068941 20211008 SMPDB SMP:00725 18460876 PMM1 phosphomannomutase 1 gene PW:0002388 fructosuria pathway ISO RGD:1322064 W RGD:9068941 20211008 SMPDB SMP:00561 18460919 BAD BCL2 associated agonist of cell death gene PW:0000104 intrinsic apoptotic pathway ISO RGD:733062 W RGD:9068941 20211008 RGD PMID:15632274|REF_RGD_ID:1579966 18460919 BAD BCL2 associated agonist of cell death gene PW:0000104 intrinsic apoptotic pathway ISO RGD:735541 W RGD:9068941 20211008 RGD PMID:19641503|REF_RGD_ID:2314029 18460919 BAD BCL2 associated agonist of cell death gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:735541 W RGD:9068941 20211008 PID PID:200197 18460919 BAD BCL2 associated agonist of cell death gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:735541 W RGD:9068941 20211008 PID PID:200100 18460919 BAD BCL2 associated agonist of cell death gene PW:0000611 endometrial cancer pathway ISO RGD:735541 W RGD:9068941 20211008 RGD PMID:12790783|REF_RGD_ID:13432162 18460919 BAD BCL2 associated agonist of cell death gene PW:0000961 ceramide signaling pathway ISO RGD:735541 W RGD:9068941 20211008 PID PID:200119 18460919 BAD BCL2 associated agonist of cell death gene PW:0000998 adenosine signaling pathway ISO RGD:735541 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18460946 QPRT quinolinate phosphoribosyltransferase gene PW:0001010 niacin metabolic pathway ISO RGD:1321139 W RGD:9068941 20211008 SMPDB SMP:00048 18460946 QPRT quinolinate phosphoribosyltransferase gene PW:0001276 de novo nicotinamide adenine dinucleotide biosynthetic pathway ISO RGD:1321139 W RGD:9068941 20211008 RGD PMID:20007326|REF_RGD_ID:11099972 18461080 PPOX protoporphyrinogen oxidase gene PW:0000218 heme biosynthetic pathway ISO RGD:1310543 W RGD:9068941 20211008 RGD PMID:3663105|REF_RGD_ID:1599180 18461080 PPOX protoporphyrinogen oxidase gene PW:0000218 heme biosynthetic pathway ISO RGD:1321506 W RGD:9068941 20211008 RGD PMID:16839620|PMID:26785297|REF_RGD_ID:11554188|REF_RGD_ID:4144542 18461080 PPOX protoporphyrinogen oxidase gene PW:0001785 variegate porphyria pathway ISO RGD:1321506 W RGD:9068941 20211008 SMPDB SMP:00346 18461080 PPOX protoporphyrinogen oxidase gene PW:0001981 hereditary coproporphyria pathway ISO RGD:1321506 W RGD:9068941 20211008 SMPDB SMP:00342 18461080 PPOX protoporphyrinogen oxidase gene PW:0002017 acute intermittent porphyria pathway ISO RGD:1321506 W RGD:9068941 20211008 SMPDB SMP:00344 18461080 PPOX protoporphyrinogen oxidase gene PW:0002216 erythropoietic porphyria pathway ISO RGD:1321506 W RGD:9068941 20211008 SMPDB SMP:00345 18461080 PPOX protoporphyrinogen oxidase gene PW:0002285 porphyrin metabolic pathway ISO RGD:1321506 W RGD:9068941 20211008 SMPDB SMP:00024 18461103 TET2 tet methylcytosine dioxygenase 2 gene PW:0001340 DNA modification pathway ISO RGD:1606790 W RGD:9068941 20211008 RGD PMID:22770212|PMID:24825349|REF_RGD_ID:8695943|REF_RGD_ID:8695944 18461164 MED19 mediator complex subunit 19 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1344644 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18461174 PRMT5 protein arginine methyltransferase 5 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1319178 W RGD:9068941 20211008 RGD PMID:15866169|PMID:21074527|REF_RGD_ID:1359044|REF_RGD_ID:7242552 18461174 PRMT5 protein arginine methyltransferase 5 gene PW:0000398 homocysteine metabolic pathway ISO RGD:1319178 W RGD:9068941 20211008 RGD PMID:15866169|REF_RGD_ID:1359044 18461174 PRMT5 protein arginine methyltransferase 5 gene PW:0000718 p53 signaling pathway ISO RGD:1319178 W RGD:9068941 20211008 PID PID:200206 18461174 PRMT5 protein arginine methyltransferase 5 gene PW:0001338 histone modification pathway ISO RGD:1319178 W RGD:9068941 20211008 RGD PMID:24583552|REF_RGD_ID:9479047 18461352 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:732613 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18461352 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene PW:0001449 nicotine pharmacokinetics pathway ISO RGD:732613 W RGD:9068941 20211008 SMPDB SMP:00628 18461352 CHRNA3 cholinergic receptor nicotinic alpha 3 subunit gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:732613 W RGD:9068941 20211008 SMPDB SMP:00431 18461444 DNM1 dynamin 1 gene PW:0000204 Notch signaling pathway ISO RGD:733748 W RGD:9068941 20211008 PID PID:200015 18461444 DNM1 dynamin 1 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:733748 W RGD:9068941 20211008 PID PID:200052|PID:200204 18461444 DNM1 dynamin 1 gene PW:0000565 eicosanoid signaling pathway ISO RGD:733748 W RGD:9068941 20211008 PID PID:200082 18461444 DNM1 dynamin 1 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:733748 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0000042 galactose metabolic pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00043 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0000055 nucleotide sugar metabolic pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00010 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0000151 starch and sucrose metabolic pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00058 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0001648 congenital sucrase-isomaltase deficiency pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00557 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0001994 glycogen storage disease type III pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00553 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0001995 glycogen storage disease type IV pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00554 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0001996 glycogen storage disease type VI pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00555 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0002072 lactose biosynthetic pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00444 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0002092 galactosemia pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00182 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0002093 GALE deficiency pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00496 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0002094 galactokinase deficiency pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00495 18461525 UGP2 UDP-glucose pyrophosphorylase 2 gene PW:0002467 Glut1 deficiency syndrome pathway ISO RGD:1320978 W RGD:9068941 20211008 SMPDB SMP:00580 18461604 PC pyruvate carboxylase gene PW:0000026 citric acid cycle pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00057 18461604 PC pyruvate carboxylase gene PW:0000043 pyruvate metabolic pathway ISO RGD:3262 W RGD:9068941 20211008 RGD PMID:15507531|REF_RGD_ID:1601554 18461604 PC pyruvate carboxylase gene PW:0000043 pyruvate metabolic pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00060 18461604 PC pyruvate carboxylase gene PW:0000438 alanine metabolic pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00055 18461604 PC pyruvate carboxylase gene PW:0000641 gluconeogenesis pathway ISO RGD:3262 W RGD:9068941 20211008 RGD PMID:4353083|PMID:5773282|PMID:6049928|REF_RGD_ID:2302851|REF_RGD_ID:2302971|REF_RGD_ID:2302972 18461604 PC pyruvate carboxylase gene PW:0000641 gluconeogenesis pathway ISO RGD:733418 W RGD:9068941 20211008 RGD PMID:18613815|REF_RGD_ID:2302809 18461604 PC pyruvate carboxylase gene PW:0000641 gluconeogenesis pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00128 18461604 PC pyruvate carboxylase gene PW:0001416 Leigh disease pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00196 18461604 PC pyruvate carboxylase gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00563 18461604 PC pyruvate carboxylase gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00559 18461604 PC pyruvate carboxylase gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00212 18461604 PC pyruvate carboxylase gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00334 18461604 PC pyruvate carboxylase gene PW:0001754 pyruvate dehydrogenase E2 deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00551 18461604 PC pyruvate carboxylase gene PW:0001755 pyruvate dehydrogenase E3 deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00550 18461604 PC pyruvate carboxylase gene PW:0001775 pyruvate carboxylase deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00350 18461604 PC pyruvate carboxylase gene PW:0001782 primary hyperoxaluria type 1 pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00352 18461604 PC pyruvate carboxylase gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00558 18461604 PC pyruvate carboxylase gene PW:0001814 mitochondrial complex II deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00548 18461604 PC pyruvate carboxylase gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18461604 PC pyruvate carboxylase gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00573 18461604 PC pyruvate carboxylase gene PW:0002098 fumaric aciduria pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00547 18461604 PC pyruvate carboxylase gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00562 18461604 PC pyruvate carboxylase gene PW:0002548 lactic acidosis pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00313 18461604 PC pyruvate carboxylase gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:733418 W RGD:9068941 20211008 SMPDB SMP:00560 18461935 AFDN afadin, adherens junction formation factor gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:731514 W RGD:9068941 20211008 PID PID:200149 18462235 TNFSF11 TNF superfamily member 11 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1347343 W RGD:9068941 20211008 PID PID:200146 18462253 COL4A4 collagen type IV alpha 4 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1313332 W RGD:9068941 20211008 PID PID:200156 18462345 COPA COPI coat complex subunit alpha gene PW:0000387 Arf family mediated signaling pathway ISO RGD:1321477 W RGD:9068941 20211008 PID PID:200195 18462462 SLC34A3 solute carrier family 34 member 3 gene PW:0001183 phosphate transport pathway ISO RGD:1348656 W RGD:9068941 20211008 RGD PMID:21778753|REF_RGD_ID:7207819 18462540 POLE3 DNA polymerase epsilon 3, accessory subunit gene PW:0000130 nucleotide excision repair pathway ISO RGD:1344068 W RGD:9068941 20211008 RGD PMID:12806123|REF_RGD_ID:7246936 18462540 POLE3 DNA polymerase epsilon 3, accessory subunit gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1344068 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18462540 POLE3 DNA polymerase epsilon 3, accessory subunit gene PW:0001407 ISWI family mediated chromatin remodeling pathway ISO RGD:1344068 W RGD:9068941 20211008 RGD PMID:21358755|REF_RGD_ID:9495920 18462548 SRRM1 serine and arginine repetitive matrix 1 gene PW:0001073 spliceosome pathway ISO RGD:1322619 W RGD:9068941 20211008 RGD PMID:15145352|PMID:17537823|REF_RGD_ID:9686091|REF_RGD_ID:9686404 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1344181 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0000507 estrogen signaling pathway ISO RGD:1344181 W RGD:9068941 20211008 RGD PMID:16394250|REF_RGD_ID:5128512 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0000564 androgen signaling pathway ISO RGD:1344181 W RGD:9068941 20211008 RGD PMID:17163421|REF_RGD_ID:2326123 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0000569 cortisol signaling pathway ISO RGD:1344181 W RGD:9068941 20211008 RGD PMID:11306337|PMID:19818358|REF_RGD_ID:5144138|REF_RGD_ID:5147892 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0000839 tamoxifen pharmacodynamics pathway ISO RGD:1344181 W RGD:9068941 20211008 RGD PMID:16822624|REF_RGD_ID:5130718 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0000958 forkhead class A signaling pathway ISO RGD:1344181 W RGD:9068941 20211008 PID PID:200226 18462609 NCOA3 nuclear receptor coactivator 3 gene PW:0001014 retinoic acid signaling pathway ISO RGD:1344181 W RGD:9068941 20211008 RGD PMID:19471584|REF_RGD_ID:6484676 18462649 RPL32 ribosomal protein L32 gene PW:0000101 translation pathway ISO RGD:1347014 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18462649 RPL32 ribosomal protein L32 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1347014 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18462790 RLBP1 retinaldehyde binding protein 1 gene PW:0001005 retinoid cycle metabolic pathway ISO RGD:1320101 W RGD:9068941 20211008 RGD PMID:20188572|REF_RGD_ID:6903223 18462790 RLBP1 retinaldehyde binding protein 1 gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1320101 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18462790 RLBP1 retinaldehyde binding protein 1 gene PW:0001498 altered retinoid cycle metabolic pathway ISO RGD:1320101 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18462855 HMGN1 high mobility group nucleosome binding domain 1 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1317138 W RGD:9068941 20211008 RGD PMID:22824526|REF_RGD_ID:7246919 18462910 PRKACG protein kinase cAMP-activated catalytic subunit gamma gene PW:0000394 dopamine signaling pathway ISO RGD:1345258 W RGD:9068941 20211008 RGD PMID:21927600|REF_RGD_ID:11041163 18462910 PRKACG protein kinase cAMP-activated catalytic subunit gamma gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1345258 W RGD:9068941 20211008 RGD PMID:14715913|REF_RGD_ID:2312475 18462910 PRKACG protein kinase cAMP-activated catalytic subunit gamma gene PW:0000968 interleukin-3 signaling pathway ISO RGD:1345258 W RGD:9068941 20211008 PID PID:200145 18462910 PRKACG protein kinase cAMP-activated catalytic subunit gamma gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:1345258 W RGD:9068941 20211008 PID PID:200019 18462953 MADD MAP kinase activating death domain gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:732838 W RGD:9068941 20211008 PID PID:200102 18462953 MADD MAP kinase activating death domain gene PW:0000961 ceramide signaling pathway ISO RGD:732838 W RGD:9068941 20211008 PID PID:200119 18463102 CIAO1 cytosolic iron-sulfur assembly component 1 gene PW:0002636 cytosolic iron-sulfur cluster protein assembly pathway ISO RGD:1354495 W RGD:9068941 20211008 RGD PMID:25245479|PMID:25583461|REF_RGD_ID:11554190|REF_RGD_ID:11554192 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00023 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0000728 statin pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0001586 Wolman disease pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00389 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0001812 mevalonic aciduria pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00112 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0001933 hypercholesterolemia pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00209 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00079 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002106 desmosterolosis pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00386 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00095 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00117 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00107 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00508 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00387 18463297 SOAT1 sterol O-acyltransferase 1 gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:731038 W RGD:9068941 20211008 SMPDB SMP:00388 18463480 INO80B INO80 complex subunit B gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1347975 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18463657 IL2 interleukin 2 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:730858 W RGD:9068941 20211008 PID PID:200098 18463657 IL2 interleukin 2 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:730858 W RGD:9068941 20211008 PID PID:200045 18463657 IL2 interleukin 2 gene PW:0000915 interleukin-23 signaling pathway ISO RGD:730858 W RGD:9068941 20211008 PID PID:200154 18463657 IL2 interleukin 2 gene PW:0000916 interleukin-27 signaling pathway ISO RGD:730858 W RGD:9068941 20211008 PID PID:200028 18463775 FXN frataxin gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1604403 W RGD:9068941 20211008 PID PID:200036 18463844 LOC103219520 splicing factor U2AF 35 kDa subunit-like protein gene PW:0001073 spliceosome pathway ISO RGD:1349504 W RGD:9068941 20211008 RGD PMID:19239890|REF_RGD_ID:9686089 18464117 IL17RD interleukin 17 receptor D gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1353408 W RGD:9068941 20211008 PID PID:200220 18464149 BTC betacellulin gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:620275 W RGD:9068941 20211008 RGD PMID:11564606|REF_RGD_ID:2324625 18464149 BTC betacellulin gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:736353 W RGD:9068941 20211008 PID PID:200159 18464149 BTC betacellulin gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:736353 W RGD:9068941 20211008 RGD PMID:15982853|REF_RGD_ID:2317963 18464319 POLR2F RNA polymerase II, I and III subunit F gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:734063 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18464319 POLR2F RNA polymerase II, I and III subunit F gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:734063 W RGD:9068941 20211008 RGD PMID:22960599|REF_RGD_ID:9588243 18464319 POLR2F RNA polymerase II, I and III subunit F gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:734063 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18464333 RB1CC1 RB1 inducible coiled-coil 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1319644 W RGD:9068941 20211008 PID PID:200096 18464333 RB1CC1 RB1 inducible coiled-coil 1 gene PW:0000278 autophagy pathway ISO RGD:1319644 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18464406 HAL histidine ammonia-lyase gene PW:0000051 histidine metabolic pathway ISO RGD:68517 W RGD:9068941 20211008 SMPDB SMP:00044 18464406 HAL histidine ammonia-lyase gene PW:0001978 histidinemia pathway ISO RGD:68517 W RGD:9068941 20211008 SMPDB SMP:00191 18464522 COX15 COX15, cytochrome c oxidase assembly homolog gene PW:0001785 variegate porphyria pathway ISO RGD:1323821 W RGD:9068941 20211008 SMPDB SMP:00346 18464522 COX15 COX15, cytochrome c oxidase assembly homolog gene PW:0001981 hereditary coproporphyria pathway ISO RGD:1323821 W RGD:9068941 20211008 SMPDB SMP:00342 18464522 COX15 COX15, cytochrome c oxidase assembly homolog gene PW:0002017 acute intermittent porphyria pathway ISO RGD:1323821 W RGD:9068941 20211008 SMPDB SMP:00344 18464522 COX15 COX15, cytochrome c oxidase assembly homolog gene PW:0002216 erythropoietic porphyria pathway ISO RGD:1323821 W RGD:9068941 20211008 SMPDB SMP:00345 18464522 COX15 COX15, cytochrome c oxidase assembly homolog gene PW:0002285 porphyrin metabolic pathway ISO RGD:1323821 W RGD:9068941 20211008 SMPDB SMP:00024 18464867 RAB8B RAB8B, member RAS oncogene family gene PW:0000159 Rab family mediated signaling pathway ISO RGD:1350755 W RGD:9068941 20211008 RGD PMID:18570632|REF_RGD_ID:2302397 18464867 RAB8B RAB8B, member RAS oncogene family gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1350755 W RGD:9068941 20211008 RGD PMID:18570632|REF_RGD_ID:2302397 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 PID PID:200018 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 RGD PMID:17481747|REF_RGD_ID:2293891 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 PID PID:200188 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 PID PID:200146 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000565 eicosanoid signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 PID PID:200082 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000681 FasL mediated signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 PID PID:200080 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 PID PID:200098 18464882 MAPK11 mitogen-activated protein kinase 11 gene PW:0000998 adenosine signaling pathway ISO RGD:1319634 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18464950 CSNK1G2 casein kinase 1 gamma 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:734368 W RGD:9068941 20211008 PID PID:200172 18464950 CSNK1G2 casein kinase 1 gamma 2 gene PW:0000718 p53 signaling pathway ISO RGD:734368 W RGD:9068941 20211008 PID PID:200206 18465436 SHF Src homology 2 domain containing F gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1602197 W RGD:9068941 20211008 PID PID:200162 18465526 ITGAX integrin subunit alpha X gene PW:0000286 integrin mediated signaling pathway ISO RGD:1348968 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18465570 KLK3 kallikrein related peptidase 3 gene PW:0000958 forkhead class A signaling pathway ISO RGD:1343198 W RGD:9068941 20211008 PID PID:200226 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0000141 retinol metabolic pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00074 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00648 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00600 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00433 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00622 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00406 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00590 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00086 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00640 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00336 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00327 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00601 18465594 PDIA2 protein disulfide isomerase family A member 2 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:1313029 W RGD:9068941 20211008 SMPDB SMP:00442 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0000141 retinol metabolic pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00074 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00648 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00600 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00433 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00622 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00406 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00590 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00086 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00640 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00336 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00327 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00601 18465705 PDIA6 protein disulfide isomerase family A member 6 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:1354298 W RGD:9068941 20211008 SMPDB SMP:00442 18465734 BHLHE41 basic helix-loop-helix family member e41 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:731061 W RGD:9068941 20211008 PID PID:200202 18465789 RPL13 ribosomal protein L13 gene PW:0000101 translation pathway ISO RGD:732066 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18465789 RPL13 ribosomal protein L13 gene PW:0001066 ribosome biogenesis pathway ISO RGD:732066 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18465799 EDNRA endothelin receptor type A gene PW:0000024 inflammatory response pathway ISO RGD:2535 W RGD:9068941 20211008 RGD PMID:20409845|REF_RGD_ID:4892591 18465799 EDNRA endothelin receptor type A gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:2535 W RGD:9068941 20211008 RGD PMID:16543720|REF_RGD_ID:4892323 18465799 EDNRA endothelin receptor type A gene PW:0000506 endothelin signaling pathway ISO RGD:2535 W RGD:9068941 20211008 RGD PMID:20409845|REF_RGD_ID:4892591 18465799 EDNRA endothelin receptor type A gene PW:0000506 endothelin signaling pathway ISO RGD:737537 W RGD:9068941 20211008 PID PID:200005 18465893 PYGL glycogen phosphorylase L gene PW:0000151 starch and sucrose metabolic pathway ISO RGD:731803 W RGD:9068941 20211008 SMPDB SMP:00058 18465893 PYGL glycogen phosphorylase L gene PW:0000533 glycogen metabolic pathway ISO RGD:620687 W RGD:9068941 20211008 RGD PMID:15138155|REF_RGD_ID:1582633 18465893 PYGL glycogen phosphorylase L gene PW:0000534 glycogen degradation pathway ISO RGD:620687 W RGD:9068941 20211008 RGD PMID:15138155|PMID:16125296|REF_RGD_ID:1582633|REF_RGD_ID:1601233 18465893 PYGL glycogen phosphorylase L gene PW:0000534 glycogen degradation pathway ISO RGD:731803 W RGD:9068941 20211008 RGD PMID:11340058|PMID:1544539|REF_RGD_ID:1642822|REF_RGD_ID:2304109 18465893 PYGL glycogen phosphorylase L gene PW:0001648 congenital sucrase-isomaltase deficiency pathway ISO RGD:731803 W RGD:9068941 20211008 SMPDB SMP:00557 18465893 PYGL glycogen phosphorylase L gene PW:0001994 glycogen storage disease type III pathway ISO RGD:731803 W RGD:9068941 20211008 SMPDB SMP:00553 18465893 PYGL glycogen phosphorylase L gene PW:0001995 glycogen storage disease type IV pathway ISO RGD:731803 W RGD:9068941 20211008 SMPDB SMP:00554 18465893 PYGL glycogen phosphorylase L gene PW:0001996 glycogen storage disease type VI pathway ISO RGD:731803 W RGD:9068941 20211008 SMPDB SMP:00555 18466037 COL8A2 collagen type VIII alpha 2 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1313058 W RGD:9068941 20211008 PID PID:200156 18466262 TWIST1 twist family bHLH transcription factor 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1349130 W RGD:9068941 20211008 PID PID:200036 18466369 ATP5PF ATP synthase peripheral stalk subunit F6 gene PW:0000958 forkhead class A signaling pathway ISO RGD:735304 W RGD:9068941 20211008 PID PID:200226 18466402 NSMAF neutral sphingomyelinase activation associated factor gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1352100 W RGD:9068941 20211008 PID PID:200102 18466402 NSMAF neutral sphingomyelinase activation associated factor gene PW:0000961 ceramide signaling pathway ISO RGD:1352100 W RGD:9068941 20211008 PID PID:200119 18466599 NRG4 neuregulin 4 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1606150 W RGD:9068941 20211008 PID PID:200159 18466599 NRG4 neuregulin 4 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:1606150 W RGD:9068941 20211008 RGD PMID:18519747|REF_RGD_ID:2317965 18467196 ROMO1 reactive oxygen species modulator 1 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1349152 W RGD:9068941 20211008 RGD PMID:25542066|PMID:25633533|REF_RGD_ID:10412658|REF_RGD_ID:10412659 18467279 GNAT2 G protein subunit alpha transducin 2 gene PW:0000962 visual phototransduction pathway ISO RGD:1319893 W RGD:9068941 20211008 RGD PMID:22074925|REF_RGD_ID:6893539 18467323 CTDSP1 CTD small phosphatase 1 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1313770 W RGD:9068941 20211008 RGD pol II carboxyl-terminal domain (CTD) PMID:22622228|PMID:23837720|REF_RGD_ID:9681737|REF_RGD_ID:9681738 18467323 CTDSP1 CTD small phosphatase 1 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1313770 W RGD:9068941 20211008 PID PID:200144 18467790 CYTH2 cytohesin 2 gene PW:0000387 Arf family mediated signaling pathway ISO RGD:737071 W RGD:9068941 20211008 PID PID:200195 18467790 CYTH2 cytohesin 2 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:737071 W RGD:9068941 20211008 PID PID:200116 18467909 CEBPD CCAAT enhancer binding protein delta gene PW:0000516 interleukin-6 signaling pathway ISO RGD:736554 W RGD:9068941 20211008 PID PID:200146 18467909 CEBPD CCAAT enhancer binding protein delta gene PW:0000958 forkhead class A signaling pathway ISO RGD:736554 W RGD:9068941 20211008 PID PID:200087 18467915 NRK Nik related kinase gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1344667 W RGD:9068941 20211008 PID PID:200102 18467955 PPIL1 peptidylprolyl isomerase like 1 gene PW:0001073 spliceosome pathway ISO RGD:1319281 W RGD:9068941 20211008 RGD PMID:18544344|PMID:23742842|REF_RGD_ID:9686094|REF_RGD_ID:9686376 18468177 ORC1 origin recognition complex subunit 1 gene PW:0001338 histone modification pathway ISO RGD:1350406 W RGD:9068941 20211008 RGD PMID:23642229|REF_RGD_ID:9479074 18468222 NDP norrin cystine knot growth factor NDP gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1343189 W RGD:9068941 20211008 RGD PMID:23085770|REF_RGD_ID:7365107 18468321 LOC103248766 fasciculation and elongation protein zeta-1 gene PW:0002061 mitochondria transport pathway ISO RGD:732377 W RGD:9068941 20211008 RGD PMID:25612908|REF_RGD_ID:10402141 18468338 HNRNPU heterogeneous nuclear ribonucleoprotein U gene PW:0001073 spliceosome pathway ISO RGD:731482 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18468626 CCN2 cellular communication network factor 2 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:731013 W RGD:9068941 20211008 PID PID:200227 18468726 POLR2C RNA polymerase II subunit C gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1315832 W RGD:9068941 20211008 RGD PMID:22960599|REF_RGD_ID:9588243 18469032 TUT4 terminal uridylyl transferase 4 gene PW:0000808 microRNA pathway ISO RGD:1320865 W RGD:9068941 20211008 RGD PMID:23622238|REF_RGD_ID:9850106 18469120 IL17F interleukin 17F gene PW:0000915 interleukin-23 signaling pathway ISO RGD:1322840 W RGD:9068941 20211008 PID PID:200154 18469294 DDX18 DEAD-box helicase 18 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1348568 W RGD:9068941 20211008 RGD PMID:22922795|REF_RGD_ID:10002738 18469340 TGFB3 transforming growth factor beta 3 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:735686 W RGD:9068941 20211008 PID PID:200227 18469340 TGFB3 transforming growth factor beta 3 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:735686 W RGD:9068941 20211008 RGD PMID:12809600|REF_RGD_ID:2298922 18469340 TGFB3 transforming growth factor beta 3 gene PW:0000658 glypican signaling pathway ISO RGD:735686 W RGD:9068941 20211008 PID PID:200026 18469351 WNT7B Wnt family member 7B gene PW:0000008 Wnt signaling pathway ISO RGD:1322906 W RGD:9068941 20211008 RGD 18469351 WNT7B Wnt family member 7B gene PW:0000008 Wnt signaling pathway ISO RGD:1322907 W RGD:9068941 20211008 RGD 18469351 WNT7B Wnt family member 7B gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1311441 W RGD:9068941 20211008 RGD PMID:18177422|REF_RGD_ID:2292645 18469351 WNT7B Wnt family member 7B gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1322907 W RGD:9068941 20211008 RGD PMID:15608632|REF_RGD_ID:1581694 18469351 WNT7B Wnt family member 7B gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1322906 W RGD:9068941 20211008 RGD PMID:18765832|REF_RGD_ID:2313743 18469351 WNT7B Wnt family member 7B gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1322907 W RGD:9068941 20211008 RGD PMID:15923619|REF_RGD_ID:2293491 18469351 WNT7B Wnt family member 7B gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:3258 W RGD:9068941 20211008 RGD PMID:16164600|REF_RGD_ID:1601222 18469575 SFRP5 secreted frizzled related protein 5 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1321235 W RGD:9068941 20211008 RGD PMID:23085770|REF_RGD_ID:7365107 18469598 MFAP2 microfibril associated protein 2 gene PW:0000204 Notch signaling pathway ISO RGD:1314413 W RGD:9068941 20211008 PID PID:200015 18469688 SMARCE1 SWI/SNF related BAF chromatin remodeling complex subunit E1 gene PW:0001406 SWI/SNF family mediated chromatin remodeling pathway ISO RGD:1313743 W RGD:9068941 20211008 RGD PMID:21358755|PMID:23355908|REF_RGD_ID:8694154|REF_RGD_ID:9495920 18470023 PRKCE protein kinase C epsilon gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:736442 W RGD:9068941 20211008 PID PID:200149 18470023 PRKCE protein kinase C epsilon gene PW:0000506 endothelin signaling pathway ISO RGD:736442 W RGD:9068941 20211008 PID PID:200005 18470023 PRKCE protein kinase C epsilon gene PW:0000565 eicosanoid signaling pathway ISO RGD:736442 W RGD:9068941 20211008 PID PID:200082 18470023 PRKCE protein kinase C epsilon gene PW:0000840 protein kinase C (PKC) signaling pathway ISO RGD:736442 W RGD:9068941 20211008 RGD PMID:19934406|REF_RGD_ID:5131489 18470023 PRKCE protein kinase C epsilon gene PW:0000907 interleukin-2 signaling pathway ISO RGD:736442 W RGD:9068941 20211008 PID PID:200098 18470233 RGS6 regulator of G protein signaling 6 gene PW:0000843 acetylcholine signaling pathway via muscarinic acetylcholine receptor ISO RGD:736971 W RGD:9068941 20211008 RGD PMID:22685433|REF_RGD_ID:8549594 18470381 INPP4B inositol polyphosphate-4-phosphatase type II B gene PW:0000154 inositol phosphate metabolic pathway ISO RGD:734292 W RGD:9068941 20211008 SMPDB SMP:00462 18470381 INPP4B inositol polyphosphate-4-phosphatase type II B gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:734292 W RGD:9068941 20211008 SMPDB SMP:00463 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0000383 multispecific organic anion transporter mediated transport pathway ISO RGD:69338 W RGD:9068941 20211008 RGD PMID:9228014|REF_RGD_ID:68822 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00590 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00086 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00133 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00132 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00134 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001880 iminoglycinuria pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00193 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00105 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0001977 Hartnup disease pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00189 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00100 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00115 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00097 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00122 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00088 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00078 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00090 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002214 cystinuria pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00723 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00118 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00135 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00121 18470533 SLC22A6 solute carrier family 22 member 6 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:619572 W RGD:9068941 20211008 SMPDB SMP:00108 18470587 SGMS1 sphingomyelin synthase 1 gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1352309 W RGD:9068941 20211008 SMPDB SMP:00034 18470587 SGMS1 sphingomyelin synthase 1 gene PW:0001454 Gaucher's disease pathway ISO RGD:1352309 W RGD:9068941 20211008 SMPDB SMP:00349 18470587 SGMS1 sphingomyelin synthase 1 gene PW:0002021 Krabbe disease pathway ISO RGD:1352309 W RGD:9068941 20211008 SMPDB SMP:00348 18470587 SGMS1 sphingomyelin synthase 1 gene PW:0002103 Fabry disease pathway ISO RGD:1352309 W RGD:9068941 20211008 SMPDB SMP:00525 18470587 SGMS1 sphingomyelin synthase 1 gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1352309 W RGD:9068941 20211008 SMPDB SMP:00347 18470724 RGMB repulsive guidance molecule BMP co-receptor b gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1350725 W RGD:9068941 20211008 PID PID:200144 18470736 GNAL G protein subunit alpha L gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:1349997 W RGD:9068941 20211008 RGD PMID:24144882|REF_RGD_ID:11041135 18470736 GNAL G protein subunit alpha L gene PW:0000506 endothelin signaling pathway ISO RGD:1349997 W RGD:9068941 20211008 PID PID:200005 18470736 GNAL G protein subunit alpha L gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:1349997 W RGD:9068941 20211008 RGD PMID:24144882|REF_RGD_ID:11041135 18471307 GMDS GDP-mannose 4,6-dehydratase gene PW:0000041 fructose and mannose metabolic pathway ISO RGD:1322234 W RGD:9068941 20211008 SMPDB SMP:00064 18471307 GMDS GDP-mannose 4,6-dehydratase gene PW:0002101 hereditary fructose intolerance syndrome pathway ISO RGD:1322234 W RGD:9068941 20211008 SMPDB SMP:00725 18471307 GMDS GDP-mannose 4,6-dehydratase gene PW:0002388 fructosuria pathway ISO RGD:1322234 W RGD:9068941 20211008 SMPDB SMP:00561 18471368 RAPSN receptor associated protein of the synapse gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:1314836 W RGD:9068941 20211008 RGD PMID:23032192|REF_RGD_ID:8549508 18471395 KCNJ12 potassium inwardly rectifying channel subfamily J member 12 gene PW:0000274 neuron-to-neuron signaling pathway via the chemical synapse ISO RGD:621660 W RGD:9068941 20211008 RGD PMID:15936845|REF_RGD_ID:1581471 18471525 ARRB2 arrestin beta 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:731570 W RGD:9068941 20211008 PID PID:200168|PID:200172 18471525 ARRB2 arrestin beta 2 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:731570 W RGD:9068941 20211008 PID PID:200227 18471525 ARRB2 arrestin beta 2 gene PW:0000493 corticotropin-releasing hormone signaling pathway ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:16918397|REF_RGD_ID:5147673 18471525 ARRB2 arrestin beta 2 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:731570 W RGD:9068941 20211008 PID PID:200021 18471525 ARRB2 arrestin beta 2 gene PW:0000527 angiotensin II signaling pathway via AT1 receptor ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:16304060|REF_RGD_ID:5133417 18471525 ARRB2 arrestin beta 2 gene PW:0000565 eicosanoid signaling pathway ISO RGD:731570 W RGD:9068941 20211008 PID PID:200082 18471525 ARRB2 arrestin beta 2 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:731570 W RGD:9068941 20211008 PID PID:200020 18471525 ARRB2 arrestin beta 2 gene PW:0000794 epinephrine signaling pathway via adrenergic receptor beta ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:18268361|PMID:19229505|REF_RGD_ID:4140419|REF_RGD_ID:5135529 18471525 ARRB2 arrestin beta 2 gene PW:0000851 dopamine signaling pathway via D1 family of receptors ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18471525 ARRB2 arrestin beta 2 gene PW:0000852 dopamine signaling pathway via D2 family of receptors ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:21303898|REF_RGD_ID:11041134 18471525 ARRB2 arrestin beta 2 gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:20703892|REF_RGD_ID:7207469 18471525 ARRB2 arrestin beta 2 gene PW:0001141 calcium signaling pathway via the calcium-sensing receptor ISO RGD:2157 W RGD:9068941 20211008 RGD PMID:22192592|REF_RGD_ID:7207059 18471525 ARRB2 arrestin beta 2 gene PW:0001141 calcium signaling pathway via the calcium-sensing receptor ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:15637145|REF_RGD_ID:7207060 18471525 ARRB2 arrestin beta 2 gene PW:0001480 kinin signaling pathway ISO RGD:731570 W RGD:9068941 20211008 RGD PMID:21145390|REF_RGD_ID:7411621 18471583 MYBL1 MYB proto-oncogene like 1 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1315840 W RGD:9068941 20211008 PID PID:200022 18471608 CD55 CD55 molecule (Cromer blood group) gene PW:0000502 complement system pathway ISO RGD:620651 W RGD:9068941 20211008 RGD PMID:10929073|REF_RGD_ID:2326180 18471642 APRT adenine phosphoribosyltransferase gene PW:0000031 purine metabolic pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00050 18471642 APRT adenine phosphoribosyltransferase gene PW:0001590 xanthinuria pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00220 18471642 APRT adenine phosphoribosyltransferase gene PW:0001591 xanthinuria type I pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00512 18471642 APRT adenine phosphoribosyltransferase gene PW:0001592 xanthinuria type II pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00513 18471642 APRT adenine phosphoribosyltransferase gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00210 18471642 APRT adenine phosphoribosyltransferase gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00537 18471642 APRT adenine phosphoribosyltransferase gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00203 18471642 APRT adenine phosphoribosyltransferase gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00364 18471642 APRT adenine phosphoribosyltransferase gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00365 18471642 APRT adenine phosphoribosyltransferase gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00428 18471642 APRT adenine phosphoribosyltransferase gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00427 18471642 APRT adenine phosphoribosyltransferase gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00167 18471642 APRT adenine phosphoribosyltransferase gene PW:0002294 AICA-ribosuria pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00168 18471642 APRT adenine phosphoribosyltransferase gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00430 18471642 APRT adenine phosphoribosyltransferase gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:1317133 W RGD:9068941 20211008 SMPDB SMP:00535 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:735555 W RGD:9068941 20211008 RGD PMID:16876788|REF_RGD_ID:2316857 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00023 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0000728 statin pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0000776 ketone bodies biosynthetic pathway ISO RGD:70970 W RGD:9068941 20211008 RGD PMID:9893938|REF_RGD_ID:2326134 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0000958 forkhead class A signaling pathway ISO RGD:735555 W RGD:9068941 20211008 PID PID:200087 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0001586 Wolman disease pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00389 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0001812 mevalonic aciduria pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00112 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0001933 hypercholesterolemia pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00209 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00079 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002106 desmosterolosis pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00386 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00095 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00117 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00107 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00508 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00387 18471698 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:735555 W RGD:9068941 20211008 SMPDB SMP:00388 18471807 CEPT1 choline/ethanolamine phosphotransferase 1 gene PW:0001876 plasmalogen metabolic pathway ISO RGD:1345389 W RGD:9068941 20211008 SMPDB SMP:00479 18471807 CEPT1 choline/ethanolamine phosphotransferase 1 gene PW:0001877 plasmalogen biosynthetic pathway ISO RGD:1345389 W RGD:9068941 20211008 SMPDB SMP:00479 18471836 GCGR glucagon receptor gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:2669 W RGD:9068941 20211008 RGD PMID:17010343|REF_RGD_ID:2315004 18471836 GCGR glucagon receptor gene PW:0000676 glucagon signaling pathway ISO RGD:2669 W RGD:9068941 20211008 RGD PMID:15687107|PMID:17010343|REF_RGD_ID:1625210|REF_RGD_ID:2315004 18471892 DHRS3 dehydrogenase/reductase 3 gene PW:0000141 retinol metabolic pathway ISO RGD:1313699 W RGD:9068941 20211008 SMPDB SMP:00074 18471892 DHRS3 dehydrogenase/reductase 3 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1313699 W RGD:9068941 20211008 SMPDB SMP:00336 18471987 COL4A5 collagen type IV alpha 5 chain gene PW:0000659 syndecan signaling pathway ISO RGD:1351504 W RGD:9068941 20211008 PID PID:200156 18472068 TRAK2 trafficking kinesin protein 2 gene PW:0002061 mitochondria transport pathway ISO RGD:1352646 W RGD:9068941 20211008 RGD PMID:25612908|REF_RGD_ID:10402141 18472200 SFRP1 secreted frizzled related protein 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:735754 W RGD:9068941 20211008 RGD PMID:23085770|REF_RGD_ID:7365107 18472211 MDH1 malate dehydrogenase 1 gene PW:0000043 pyruvate metabolic pathway ISO RGD:732327 W RGD:9068941 20211008 SMPDB SMP:00060 18472211 MDH1 malate dehydrogenase 1 gene PW:0001416 Leigh disease pathway ISO RGD:732327 W RGD:9068941 20211008 SMPDB SMP:00196 18472211 MDH1 malate dehydrogenase 1 gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:732327 W RGD:9068941 20211008 SMPDB SMP:00559 18472211 MDH1 malate dehydrogenase 1 gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:732327 W RGD:9068941 20211008 SMPDB SMP:00212 18472211 MDH1 malate dehydrogenase 1 gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:732327 W RGD:9068941 20211008 SMPDB SMP:00334 18472211 MDH1 malate dehydrogenase 1 gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:732327 W RGD:9068941 20211008 SMPDB SMP:00558 18472211 MDH1 malate dehydrogenase 1 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:732327 W RGD:9068941 20211008 RGD PMID:16368075|PMID:18020963|REF_RGD_ID:11251688|REF_RGD_ID:5129954 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00133 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00132 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00134 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001880 iminoglycinuria pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00193 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00105 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0001977 Hartnup disease pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00189 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00100 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00115 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00097 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00122 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00088 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00078 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00090 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002214 cystinuria pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00723 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00118 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00135 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00121 18472327 SCNN1G sodium channel epithelial 1 subunit gamma gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:732847 W RGD:9068941 20211008 SMPDB SMP:00108 18472747 PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 gene PW:0000043 pyruvate metabolic pathway ISO RGD:1351234 W RGD:9068941 20211008 RGD PMID:11795479|REF_RGD_ID:2307427 18472816 SGPL1 sphingosine-1-phosphate lyase 1 gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1347742 W RGD:9068941 20211008 SMPDB SMP:00034 18472816 SGPL1 sphingosine-1-phosphate lyase 1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:1347742 W RGD:9068941 20211008 PID PID:200123 18472816 SGPL1 sphingosine-1-phosphate lyase 1 gene PW:0001454 Gaucher's disease pathway ISO RGD:1347742 W RGD:9068941 20211008 SMPDB SMP:00349 18472816 SGPL1 sphingosine-1-phosphate lyase 1 gene PW:0002021 Krabbe disease pathway ISO RGD:1347742 W RGD:9068941 20211008 SMPDB SMP:00348 18472816 SGPL1 sphingosine-1-phosphate lyase 1 gene PW:0002103 Fabry disease pathway ISO RGD:1347742 W RGD:9068941 20211008 SMPDB SMP:00525 18472816 SGPL1 sphingosine-1-phosphate lyase 1 gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1347742 W RGD:9068941 20211008 SMPDB SMP:00347 18472840 EIF4B eukaryotic translation initiation factor 4B gene PW:0000180 mTOR signaling pathway ISO RGD:1315118 W RGD:9068941 20211008 PID PID:200096 18472840 EIF4B eukaryotic translation initiation factor 4B gene PW:0000580 translation initiation pathway ISO RGD:1315118 W RGD:9068941 20211008 RGD PMID:21427765|REF_RGD_ID:10044021 18472868 TXNL4A thioredoxin like 4A gene PW:0001073 spliceosome pathway ISO RGD:1347193 W RGD:9068941 20211008 RGD PMID:19239890|REF_RGD_ID:9686089 18472892 CHPT1 choline phosphotransferase 1 gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:1349185 W RGD:9068941 20211008 SMPDB SMP:00025 18472892 CHPT1 choline phosphotransferase 1 gene PW:0001431 lamivudine pharmacokinetics pathway ISO RGD:1349185 W RGD:9068941 20211008 SMPDB SMP:00649 18472911 CH25H cholesterol 25-hydroxylase gene PW:0000039 bile acid biosynthetic pathway ISO RGD:1321560 W RGD:9068941 20211008 SMPDB SMP:00035 18472911 CH25H cholesterol 25-hydroxylase gene PW:0001415 Zellweger syndrome pathway ISO RGD:1321560 W RGD:9068941 20211008 SMPDB SMP:00316 18472911 CH25H cholesterol 25-hydroxylase gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:1321560 W RGD:9068941 20211008 SMPDB SMP:00315 18472911 CH25H cholesterol 25-hydroxylase gene PW:0002302 familial hypercholanemia pathway ISO RGD:1321560 W RGD:9068941 20211008 SMPDB SMP:00317 18472911 CH25H cholesterol 25-hydroxylase gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:1321560 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18472939 PLG plasminogen gene PW:0000481 fibrinolysis pathway ISO RGD:1343043 W RGD:9068941 20211008 RGD PMID:26149056|REF_RGD_ID:11352249 18472939 PLG plasminogen gene PW:0000659 syndecan signaling pathway ISO RGD:1343043 W RGD:9068941 20211008 PID PID:200134 18472939 PLG plasminogen gene PW:0000731 warfarin pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00268 18472939 PLG plasminogen gene PW:0001600 acenocoumarol pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00269 18472939 PLG plasminogen gene PW:0001637 alteplase pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00280 18472939 PLG plasminogen gene PW:0001655 aminocaproic acid pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00286 18472939 PLG plasminogen gene PW:0001664 anistreplase pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00281 18472939 PLG plasminogen gene PW:0001788 tranexamic acid pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00287 18472939 PLG plasminogen gene PW:0002149 bivalirudin pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00277 18472939 PLG plasminogen gene PW:0002223 aprotinin pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00288 18472939 PLG plasminogen gene PW:0002229 argatroban pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00276 18472939 PLG plasminogen gene PW:0002258 reteplase pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00285 18472939 PLG plasminogen gene PW:0002329 heparin pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00274 18472939 PLG plasminogen gene PW:0002332 enoxaparin pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00272 18472939 PLG plasminogen gene PW:0002437 fondaparinux pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00273 18472939 PLG plasminogen gene PW:0002494 phenindione pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00655 18472939 PLG plasminogen gene PW:0002497 dicoumarol pharmacodynamics pathway ISO RGD:1343043 W RGD:9068941 20211008 SMPDB SMP:00270|SMP:00656 18472972 BCL3 BCL3 transcription coactivator gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1314971 W RGD:9068941 20211008 PID PID:200021 18473141 POP1 POP1 homolog, ribonuclease P/MRP subunit gene PW:0001573 tRNA maturation pathway ISO RGD:1318482 W RGD:9068941 20211008 RGD PMID:19931535|REF_RGD_ID:9685326 18473480 ICAM1 intercellular adhesion molecule 1 gene PW:0000565 eicosanoid signaling pathway ISO RGD:69659 W RGD:9068941 20211008 PID PID:200082 18473480 ICAM1 intercellular adhesion molecule 1 gene PW:0000926 pro-inflammatory cytokine mediated pathway ISO RGD:2857 W RGD:9068941 20211008 RGD MMO:0000166, MMO:0000669, MMO:0000656 PMID:29091898|REF_RGD_ID:15090820 18473541 ARL6 ARF like GTPase 6 gene PW:0000387 Arf family mediated signaling pathway ISO RGD:1313618 W RGD:9068941 20211008 RGD PMID:15314642|REF_RGD_ID:1578724 18473599 CALB1 calbindin 1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:732083 W RGD:9068941 20211008 RGD PMID:20943758|REF_RGD_ID:7204685 18473646 USH1G USH1 protein network component sans gene PW:0001497 retinitis pigmentosa pathway ISO RGD:1312053 W RGD:9068941 20211008 RGD PMID:20212494|REF_RGD_ID:8547536 18473646 USH1G USH1 protein network component sans gene PW:0001503 auditory mechanotransduction pathway ISO RGD:1312053 W RGD:9068941 20211008 RGD PMID:22177415|REF_RGD_ID:8547671 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 PID PID:200018 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 PID PID:200102 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 RGD PMID:21135871|REF_RGD_ID:5490225 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 PID PID:200144 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 PID PID:200227 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 RGD PMID:21135871|REF_RGD_ID:5490225 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1319911 W RGD:9068941 20211008 PID PID:200020 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 RGD PMID:20940366|REF_RGD_ID:5685016 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 PID PID:200089 18473823 TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1319911 W RGD:9068941 20211008 RGD PMID:18535784|PMID:20086235|REF_RGD_ID:5490215|REF_RGD_ID:5490218 18473956 RPL12 ribosomal protein L12 gene PW:0000101 translation pathway ISO RGD:1314871 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18473956 RPL12 ribosomal protein L12 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1314871 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18473998 DOK2 docking protein 2 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:1322166 W RGD:9068941 20211008 PID PID:200098 18473998 DOK2 docking protein 2 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:1322166 W RGD:9068941 20211008 PID PID:200022 18474159 LDHD lactate dehydrogenase D gene PW:0000043 pyruvate metabolic pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00060 18474159 LDHD lactate dehydrogenase D gene PW:0001416 Leigh disease pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00196 18474159 LDHD lactate dehydrogenase D gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00559 18474159 LDHD lactate dehydrogenase D gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00212 18474159 LDHD lactate dehydrogenase D gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00334 18474159 LDHD lactate dehydrogenase D gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00558 18474159 LDHD lactate dehydrogenase D gene PW:0002615 glyoxalase metabolic pathway ISO RGD:1317689 W RGD:9068941 20211008 SMPDB SMP:00459 18474225 LOC103223672 low affinity immunoglobulin gamma Fc region receptor II-b gene PW:0001142 clathrin-mediated endocytosis pathway ISO RGD:631331 W RGD:9068941 20211008 RGD PMID:17680646|REF_RGD_ID:9588617 18474335 UBE2V1 ubiquitin conjugating enzyme E2 V1 gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1346082 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18474335 UBE2V1 ubiquitin conjugating enzyme E2 V1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1346082 W RGD:9068941 20211008 PID PID:200089 18474335 UBE2V1 ubiquitin conjugating enzyme E2 V1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:1346082 W RGD:9068941 20211008 RGD PMID:18535784|PMID:20086235|REF_RGD_ID:5490215|REF_RGD_ID:5490218 18474398 SLC25A28 solute carrier family 25 member 28 gene PW:0002631 iron uptake pathway ISO RGD:1312988 W RGD:9068941 20211008 RGD PMID:25661197|REF_RGD_ID:11554199 18474543 ACAD9 acyl-CoA dehydrogenase family member 9 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1348095 W RGD:9068941 20211008 RGD PMID:14728676|REF_RGD_ID:2317589 18474806 MAT1A methionine adenosyltransferase 1A gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:3050 W RGD:9068941 20211008 RGD PMID:2292587|PMID:9202427|REF_RGD_ID:1359039|REF_RGD_ID:7242932 18474806 MAT1A methionine adenosyltransferase 1A gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:732753 W RGD:9068941 20211008 RGD PMID:23073625|REF_RGD_ID:7242425 18475046 RFC1 replication factor C subunit 1 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1353491 W RGD:9068941 20211008 RGD PMID:23545418|REF_RGD_ID:7246932 18475046 RFC1 replication factor C subunit 1 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1353491 W RGD:9068941 20211008 SMPDB SMP:00478 18475046 RFC1 replication factor C subunit 1 gene PW:0000662 mismatch repair pathway ISO RGD:1353491 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18475046 RFC1 replication factor C subunit 1 gene PW:0000681 FasL mediated signaling pathway ISO RGD:1353491 W RGD:9068941 20211008 PID PID:200080 18475080 NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic gene PW:0002636 cytosolic iron-sulfur cluster protein assembly pathway ISO RGD:1312953 W RGD:9068941 20211008 RGD PMID:25245479|PMID:25583461|REF_RGD_ID:11554190|REF_RGD_ID:11554192 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200102 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200021|PID:200031|PID:200048 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:730892 W RGD:9068941 20211008 RGD PMID:18267068|REF_RGD_ID:2292172 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:730893 W RGD:9068941 20211008 RGD PMID:23975431|REF_RGD_ID:40902973 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000883 interleukin-1 signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200089 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000914 interleukin-12 signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200045 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000915 interleukin-23 signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200154 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000926 pro-inflammatory cytokine mediated pathway ISO RGD:70498 W RGD:9068941 20211008 RGD MMO:0000166, MMO:0000669, MMO:0000656 PMID:29091898|REF_RGD_ID:15090820 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000961 ceramide signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200119 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000987 erythropoietin signaling pathway ISO RGD:730892 W RGD:9068941 20211008 PID PID:200183 18475268 NFKB1 nuclear factor kappa B subunit 1 gene PW:0000998 adenosine signaling pathway ISO RGD:730892 W RGD:9068941 20211008 SMPDB SMP:00320|SMP:00321 18475354 EIF3D eukaryotic translation initiation factor 3 subunit D gene PW:0000580 translation initiation pathway ISO RGD:1352969 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18475608 IRS1 insulin receptor substrate 1 gene PW:0000143 insulin signaling pathway ISO RGD:10816 W RGD:9068941 20211008 RGD PMID:23055040|REF_RGD_ID:7248547 18475608 IRS1 insulin receptor substrate 1 gene PW:0000143 insulin signaling pathway ISO RGD:2922 W RGD:9068941 20211008 RGD PMID:12850498|PMID:16445997|REF_RGD_ID:1580595|REF_RGD_ID:1581310 18475608 IRS1 insulin receptor substrate 1 gene PW:0000143 insulin signaling pathway ISO RGD:733473 W RGD:9068941 20211008 PID PID:200014 18475608 IRS1 insulin receptor substrate 1 gene PW:0000143 insulin signaling pathway ISO RGD:733473 W RGD:9068941 20211008 RGD PMID:23055040|REF_RGD_ID:7248547 18475608 IRS1 insulin receptor substrate 1 gene PW:0000143 insulin signaling pathway ISO RGD:733473 W RGD:9068941 20211008 SMPDB SMP:00391 18475608 IRS1 insulin receptor substrate 1 gene PW:0000180 mTOR signaling pathway ISO RGD:733473 W RGD:9068941 20211008 PID PID:200096 18475608 IRS1 insulin receptor substrate 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:2922 W RGD:9068941 20211008 RGD PMID:15272025|REF_RGD_ID:1581313 18475608 IRS1 insulin receptor substrate 1 gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:733473 W RGD:9068941 20211008 PID PID:200100 18475608 IRS1 insulin receptor substrate 1 gene PW:0000363 leptin system pathway ISO RGD:10816 W RGD:9068941 20211008 RGD PMID:15316008|REF_RGD_ID:2302071 18475608 IRS1 insulin receptor substrate 1 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:733473 W RGD:9068941 20211008 PID PID:200098 18475608 IRS1 insulin receptor substrate 1 gene PW:0000912 interleukin-4 signaling pathway ISO RGD:733473 W RGD:9068941 20211008 PID PID:200022 18475608 IRS1 insulin receptor substrate 1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:733473 W RGD:9068941 20211008 PID PID:200211 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0000034 electron transport chain pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00355 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00025 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0001156 glycerolipid metabolic pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00039 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0002018 glycerol kinase deficiency pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00187 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0002212 D-glycericacidemia pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00529 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0002557 familial lipoprotein lipase deficiency pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00530 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:737186 W RGD:9068941 20211008 RGD PMID:16368075|PMID:18020963|REF_RGD_ID:11251688|REF_RGD_ID:5129954 18475749 GPD2 glycerol-3-phosphate dehydrogenase 2 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:737186 W RGD:9068941 20211008 SMPDB SMP:00124 18475997 KAT14 lysine acetyltransferase 14 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1319928 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18476021 PALM2AKAP2 PALM2 and AKAP2 fusion gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:1603446 W RGD:9068941 20211008 RGD PMID:14715913|PMID:19319965|REF_RGD_ID:2312475|REF_RGD_ID:2312477 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000214 polyamine metabolic pathway ISO RGD:3227 W RGD:9068941 20211008 RGD PMID:10430362|REF_RGD_ID:1578320 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000214 polyamine metabolic pathway ISO RGD:731324 W RGD:9068941 20211008 RGD PMID:13678416|REF_RGD_ID:7244193 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000216 spermine metabolic pathway ISO RGD:3227 W RGD:9068941 20211008 RGD PMID:10430362|PMID:1415709|PMID:2292587|REF_RGD_ID:1578320|REF_RGD_ID:7242912|REF_RGD_ID:7242932 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000216 spermine metabolic pathway ISO RGD:731324 W RGD:9068941 20211008 SMPDB SMP:00445 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000226 putrescine metabolic pathway ISO RGD:3227 W RGD:9068941 20211008 RGD PMID:10430362|REF_RGD_ID:1578320 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000396 spermidine metabolic pathway ISO RGD:3227 W RGD:9068941 20211008 RGD PMID:10430362|PMID:1415709|PMID:2292587|REF_RGD_ID:1578320|REF_RGD_ID:7242912|REF_RGD_ID:7242932 18476074 ODC1 ornithine decarboxylase 1 gene PW:0000396 spermidine metabolic pathway ISO RGD:731324 W RGD:9068941 20211008 SMPDB SMP:00445 18476152 SFRP2 secreted frizzled related protein 2 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1345643 W RGD:9068941 20211008 RGD PMID:23085770|REF_RGD_ID:7365107 18476372 SUCLG2 succinate-CoA ligase GDP-forming subunit beta gene PW:0000026 citric acid cycle pathway ISO RGD:1305008 W RGD:9068941 20211008 RGD PMID:17403370|REF_RGD_ID:2306915 18476372 SUCLG2 succinate-CoA ligase GDP-forming subunit beta gene PW:0000026 citric acid cycle pathway ISO RGD:1312779 W RGD:9068941 20211008 SMPDB SMP:00057 18476372 SUCLG2 succinate-CoA ligase GDP-forming subunit beta gene PW:0001754 pyruvate dehydrogenase E2 deficiency pathway ISO RGD:1312779 W RGD:9068941 20211008 SMPDB SMP:00551 18476372 SUCLG2 succinate-CoA ligase GDP-forming subunit beta gene PW:0001755 pyruvate dehydrogenase E3 deficiency pathway ISO RGD:1312779 W RGD:9068941 20211008 SMPDB SMP:00550 18476372 SUCLG2 succinate-CoA ligase GDP-forming subunit beta gene PW:0001814 mitochondrial complex II deficiency pathway ISO RGD:1312779 W RGD:9068941 20211008 SMPDB SMP:00548 18476372 SUCLG2 succinate-CoA ligase GDP-forming subunit beta gene PW:0002098 fumaric aciduria pathway ISO RGD:1312779 W RGD:9068941 20211008 SMPDB SMP:00547 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0000058 fatty acid metabolic pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00051 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1342971 W RGD:9068941 20211008 RGD PMID:17762044|REF_RGD_ID:2317576 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00052|SMP:00482 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0001594 very long-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00540 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0001627 trifunctional protein deficiency pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00545 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0001667 short-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00235 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0001869 medium chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00542 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0002206 ethylmalonic encephalopathy pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00181 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0002306 glutaric aciduria type I pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00185 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0002505 adrenoleukodystrophy pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00516 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0002506 carnitine-acylcarnitine translocase deficiency ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00517 18476439 ACSL1 acyl-CoA synthetase long chain family member 1 gene PW:0002574 carnitine palmitoyltransferase I deficiency pathway ISO RGD:1342971 W RGD:9068941 20211008 SMPDB SMP:00538 18476636 PARP9 poly(ADP-ribose) polymerase family member 9 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1347584 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18476667 IMMT inner membrane mitochondrial protein gene PW:0001962 mitochondrial protein import pathway contributes_to ISO RGD:1321729 W RGD:9068941 20211008 RGD PMID:23109542|REF_RGD_ID:10412671 18476716 LSM4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated gene PW:0001073 spliceosome pathway ISO RGD:1315632 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18476964 ACTN1 actinin alpha 1 gene PW:0000659 syndecan signaling pathway ISO RGD:736411 W RGD:9068941 20211008 PID PID:200134 18476964 ACTN1 actinin alpha 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:736411 W RGD:9068941 20211008 PID PID:200182 18477008 ZZZ3 zinc finger ZZ-type containing 3 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1351388 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18477079 MGAM maltase-glucoamylase gene PW:0000151 starch and sucrose metabolic pathway ISO RGD:1318097 W RGD:9068941 20211008 SMPDB SMP:00058 18477079 MGAM maltase-glucoamylase gene PW:0001648 congenital sucrase-isomaltase deficiency pathway ISO RGD:1318097 W RGD:9068941 20211008 SMPDB SMP:00557 18477079 MGAM maltase-glucoamylase gene PW:0001994 glycogen storage disease type III pathway ISO RGD:1318097 W RGD:9068941 20211008 SMPDB SMP:00553 18477079 MGAM maltase-glucoamylase gene PW:0001995 glycogen storage disease type IV pathway ISO RGD:1318097 W RGD:9068941 20211008 SMPDB SMP:00554 18477079 MGAM maltase-glucoamylase gene PW:0001996 glycogen storage disease type VI pathway ISO RGD:1318097 W RGD:9068941 20211008 SMPDB SMP:00555 18477200 POMC proopiomelanocortin gene PW:0000359 altered energy homeostasis pathway ISO RGD:1352097 W RGD:9068941 20211008 RGD PMID:11874690|REF_RGD_ID:1357926 18477200 POMC proopiomelanocortin gene PW:0000365 melanocortin system pathway ISO RGD:1352097 W RGD:9068941 20211008 RGD PMID:11874690|PMID:15189116|REF_RGD_ID:1357925|REF_RGD_ID:1357926 18477200 POMC proopiomelanocortin gene PW:0000365 melanocortin system pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00310 18477200 POMC proopiomelanocortin gene PW:0000366 altered melanocortin system pathway ISO RGD:1352097 W RGD:9068941 20211008 RGD PMID:11874690|PMID:15189116|REF_RGD_ID:1357925|REF_RGD_ID:1357926 18477200 POMC proopiomelanocortin gene PW:0000540 obesity pathway ISO RGD:1352097 W RGD:9068941 20211008 RGD PMID:15189116|REF_RGD_ID:1357925 18477200 POMC proopiomelanocortin gene PW:0000659 syndecan signaling pathway ISO RGD:1352097 W RGD:9068941 20211008 PID PID:200198 18477200 POMC proopiomelanocortin gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00671 18477200 POMC proopiomelanocortin gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18477200 POMC proopiomelanocortin gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00431 18477200 POMC proopiomelanocortin gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00413 18477200 POMC proopiomelanocortin gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00402 18477200 POMC proopiomelanocortin gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00686 18477200 POMC proopiomelanocortin gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00687 18477200 POMC proopiomelanocortin gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00691 18477200 POMC proopiomelanocortin gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00408 18477200 POMC proopiomelanocortin gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00399 18477200 POMC proopiomelanocortin gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00422 18477200 POMC proopiomelanocortin gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00426 18477200 POMC proopiomelanocortin gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00415 18477200 POMC proopiomelanocortin gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00425 18477200 POMC proopiomelanocortin gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00423 18477200 POMC proopiomelanocortin gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00424 18477200 POMC proopiomelanocortin gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00684 18477200 POMC proopiomelanocortin gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00393 18477200 POMC proopiomelanocortin gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00401 18477200 POMC proopiomelanocortin gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00404 18477200 POMC proopiomelanocortin gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00688 18477200 POMC proopiomelanocortin gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00416 18477200 POMC proopiomelanocortin gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00397 18477200 POMC proopiomelanocortin gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00409 18477200 POMC proopiomelanocortin gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00410 18477200 POMC proopiomelanocortin gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00411 18477200 POMC proopiomelanocortin gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00412 18477200 POMC proopiomelanocortin gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00394 18477200 POMC proopiomelanocortin gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00681 18477200 POMC proopiomelanocortin gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00395 18477200 POMC proopiomelanocortin gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00398 18477200 POMC proopiomelanocortin gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00400 18477200 POMC proopiomelanocortin gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00677 18477200 POMC proopiomelanocortin gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00673 18477200 POMC proopiomelanocortin gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00407 18477200 POMC proopiomelanocortin gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:1352097 W RGD:9068941 20211008 SMPDB SMP:00675 18477335 FGF19 fibroblast growth factor 19 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1344909 W RGD:9068941 20211008 PID PID:200220 18477455 PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B gene PW:0000394 dopamine signaling pathway ISO RGD:1347073 W RGD:9068941 20211008 RGD PMID:21303898|PMID:21927600|REF_RGD_ID:11041134|REF_RGD_ID:11041163 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0000052 tyrosine metabolic pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00006 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0001608 tyrosinemia type I pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00218 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0001609 tyrosinemia type II pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00369 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0001610 tyrosinemia type III pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00370 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0001805 phenylketonuria pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00206 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00429 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0002208 dopamine beta-hydroxylase deficiency pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00498 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0002277 alkaptonuria pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00169 18477960 HPD 4-hydroxyphenylpyruvate dioxygenase gene PW:0002380 hawkinsinuria pathway ISO RGD:731782 W RGD:9068941 20211008 SMPDB SMP:00190 18478174 TMEM67 transmembrane protein 67 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1316347 W RGD:9068941 20230706 RGD PMID:26035863|REF_RGD_ID:329950577 18478384 AWAT1 acyl-CoA wax alcohol acyltransferase 1 gene PW:0000141 retinol metabolic pathway ISO RGD:1346796 W RGD:9068941 20211008 SMPDB SMP:00074 18478384 AWAT1 acyl-CoA wax alcohol acyltransferase 1 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1346796 W RGD:9068941 20211008 SMPDB SMP:00336 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000058 fatty acid metabolic pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00051 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000064 propanoate metabolic pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00016 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00032 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000738 fatty acid beta degradation pathway ISO RGD:2012 W RGD:9068941 20211008 RGD PMID:3968063|REF_RGD_ID:2317678 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000738 fatty acid beta degradation pathway ISO RGD:735259 W RGD:9068941 20211008 RGD PMID:14728676|REF_RGD_ID:2317589 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000738 fatty acid beta degradation pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00481 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0000958 forkhead class A signaling pathway ISO RGD:735259 W RGD:9068941 20211008 PID PID:200087 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001594 very long-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00540 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001627 trifunctional protein deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00545 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001667 short-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00235 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001778 propionic acidemia pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00236 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00384 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001810 methylmalonic acidemia pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00200 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001811 methylmalonic aciduria, cobalamin-related pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00201 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001869 medium chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00542 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001870 maple syrup urine disease pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00199 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001874 isovaleric acidemia pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00523 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002206 ethylmalonic encephalopathy pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00181 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00139 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00140 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002289 malonic aciduria pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00198|SMP:00502 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002306 glutaric aciduria type I pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00185 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00138 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002574 carnitine palmitoyltransferase I deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00538 18478638 ACADM acyl-CoA dehydrogenase medium chain gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:735259 W RGD:9068941 20211008 SMPDB SMP:00237 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000170 epidermal growth factor/neuregulin signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200101 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200188 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:735936 W RGD:9068941 20211008 RGD PMID:17658244|REF_RGD_ID:2298729 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200149|PID:200162 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:735936 W RGD:9068941 20211008 PID PID:200142 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200220 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000578 scatter factor/hepatocyte growth factor signaling pathway ISO RGD:735936 W RGD:9068941 20211008 RGD PMID:14685170|PMID:18175071|REF_RGD_ID:1642762|REF_RGD_ID:2299174 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200054|PID:200085 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200116 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000987 erythropoietin signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200183 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200147 18478863 PLCG1 phospholipase C gamma 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:735936 W RGD:9068941 20211008 PID PID:200209 18478863 PLCG1 phospholipase C gamma 1 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:735936 W RGD:9068941 20211008 SMPDB SMP:00358 18479010 RBKS ribokinase gene PW:0000045 pentose phosphate pathway ISO RGD:1320751 W RGD:9068941 20211008 SMPDB SMP:00031 18479010 RBKS ribokinase gene PW:0001629 transaldolase deficiency pathway ISO RGD:1320751 W RGD:9068941 20211008 SMPDB SMP:00520 18479010 RBKS ribokinase gene PW:0001704 ribose 5-phosphate isomerase deficiency pathway ISO RGD:1320751 W RGD:9068941 20211008 SMPDB SMP:00519 18479029 SLC8B1 solute carrier family 8 member B1 gene PW:0001139 calcium transport pathway ISO RGD:1349643 W RGD:9068941 20211008 RGD PMID:22850819|REF_RGD_ID:7204696 18479029 SLC8B1 solute carrier family 8 member B1 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1349643 W RGD:9068941 20211008 RGD PMID:22850819|REF_RGD_ID:7204696 18479055 ATXN7L3 ataxin 7 like 3 gene PW:0001274 RNA polymerase II transcription initiation pathway ISO RGD:1342958 W RGD:9068941 20211008 RGD PMID:22426530|REF_RGD_ID:9681728 18479103 ARNT2 aryl hydrocarbon receptor nuclear translocator 2 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:736413 W RGD:9068941 20211008 RGD PMID:22169972|REF_RGD_ID:6483352 18479103 ARNT2 aryl hydrocarbon receptor nuclear translocator 2 gene PW:0000370 aryl hydrocarbon receptor signaling pathway ISO RGD:2154 W RGD:9068941 20211008 RGD PMID:12859947|REF_RGD_ID:631760 18479183 HNRNPL heterogeneous nuclear ribonucleoprotein L gene PW:0001073 spliceosome pathway ISO RGD:737263 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18479214 ALDH1B1 aldehyde dehydrogenase 1 family member B1 gene PW:0002065 disulfiram pharmacodynamics pathway ISO RGD:1315525 W RGD:9068941 20211008 SMPDB SMP:00429 18479312 RPTOR regulatory associated protein of MTOR complex 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1311784 W RGD:9068941 20211008 RGD PMID:17110594|REF_RGD_ID:2307383 18479312 RPTOR regulatory associated protein of MTOR complex 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1603019 W RGD:9068941 20211008 PID PID:200096 18479312 RPTOR regulatory associated protein of MTOR complex 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1603019 W RGD:9068941 20211008 RGD PMID:16885148|PMID:19339977|PMID:22500797|REF_RGD_ID:11535033|REF_RGD_ID:1625616|REF_RGD_ID:2308795 18479419 FIS1 fission, mitochondrial 1 gene PW:0001998 mitochondria fission pathway ISO RGD:1315413 W RGD:9068941 20211008 RGD PMID:21683788|PMID:24442478|REF_RGD_ID:10402101|REF_RGD_ID:10402102 18479509 PELO pelota mRNA surveillance and ribosome rescue factor gene PW:0000582 translation termination pathway ISO RGD:1343336 W RGD:9068941 20211008 RGD PMID:23031510|REF_RGD_ID:10044034 18479797 PGF placental growth factor gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1347328 W RGD:9068941 20211008 RGD PMID:16633338|REF_RGD_ID:2298727 18479797 PGF placental growth factor gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:619850 W RGD:9068941 20211008 RGD PMID:7706320|REF_RGD_ID:633657 18479870 ATG13 autophagy related 13 gene PW:0000180 mTOR signaling pathway ISO RGD:1602498 W RGD:9068941 20211008 PID PID:200096 18479870 ATG13 autophagy related 13 gene PW:0000278 autophagy pathway ISO RGD:1602498 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18479987 MEAF6 MYST/Esa1 associated factor 6 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1604318 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18480068 HLX H2.0 like homeobox gene PW:0000914 interleukin-12 signaling pathway ISO RGD:1323685 W RGD:9068941 20211008 PID PID:200045 18480198 CGA glycoprotein hormones, alpha polypeptide gene PW:0001070 luteinizing hormone signaling pathway ISO RGD:1348590 W RGD:9068941 20211008 SMPDB SMP:00338 18480198 CGA glycoprotein hormones, alpha polypeptide gene PW:0001071 follicle-stimulating hormone signaling pathway ISO RGD:1348590 W RGD:9068941 20211008 SMPDB SMP:00333 18480358 LOC103232876 acetylserotonin O-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:708472 W RGD:9068941 20211008 RGD PMID:12198599|REF_RGD_ID:1359073 18480358 LOC103232876 acetylserotonin O-methyltransferase gene PW:0000054 tryptophan metabolic pathway ISO RGD:1353638 W RGD:9068941 20211008 SMPDB SMP:00063 18480422 SQLE squalene epoxidase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:736675 W RGD:9068941 20211008 RGD PMID:16876788|REF_RGD_ID:2316857 18480422 SQLE squalene epoxidase gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00023 18480422 SQLE squalene epoxidase gene PW:0000728 statin pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18480422 SQLE squalene epoxidase gene PW:0001586 Wolman disease pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18480422 SQLE squalene epoxidase gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18480422 SQLE squalene epoxidase gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00389 18480422 SQLE squalene epoxidase gene PW:0001812 mevalonic aciduria pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18480422 SQLE squalene epoxidase gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00112 18480422 SQLE squalene epoxidase gene PW:0001933 hypercholesterolemia pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00209 18480422 SQLE squalene epoxidase gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00079 18480422 SQLE squalene epoxidase gene PW:0002106 desmosterolosis pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00386 18480422 SQLE squalene epoxidase gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00095 18480422 SQLE squalene epoxidase gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00117 18480422 SQLE squalene epoxidase gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00107 18480422 SQLE squalene epoxidase gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00508 18480422 SQLE squalene epoxidase gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00387 18480422 SQLE squalene epoxidase gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:736675 W RGD:9068941 20211008 SMPDB SMP:00388 18480437 CAMK2A calcium/calmodulin dependent protein kinase II alpha gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:736752 W RGD:9068941 20211008 PID PID:200220 18480437 CAMK2A calcium/calmodulin dependent protein kinase II alpha gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:736752 W RGD:9068941 20211008 PID PID:200227 18480437 CAMK2A calcium/calmodulin dependent protein kinase II alpha gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:736752 W RGD:9068941 20211008 PID PID:200020 18480437 CAMK2A calcium/calmodulin dependent protein kinase II alpha gene PW:0000896 type II interferon signaling pathway ISO RGD:736752 W RGD:9068941 20211008 PID PID:200129 18480437 CAMK2A calcium/calmodulin dependent protein kinase II alpha gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:736752 W RGD:9068941 20211008 RGD PMID:22334212|PMID:22717267|REF_RGD_ID:7240704|REF_RGD_ID:7240705 18480645 OGG1 8-oxoguanine DNA glycosylase gene PW:0000129 base excision repair pathway ISO RGD:1353911 W RGD:9068941 20211008 RGD PMID:16221808|REF_RGD_ID:1578408 18480719 SLC39A13 solute carrier family 39 member 13 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:1551989 W RGD:9068941 20211008 RGD PMID:18985159|REF_RGD_ID:11553861 18480743 EIF2B4 eukaryotic translation initiation factor 2B subunit delta gene PW:0000580 translation initiation pathway ISO RGD:733707 W RGD:9068941 20211008 RGD PMID:22815232|REF_RGD_ID:10044017 18480827 SSB small RNA binding exonuclease protection factor La gene PW:0001573 tRNA maturation pathway ISO RGD:1348902 W RGD:9068941 20211008 RGD PMID:21572561|REF_RGD_ID:9685334 18480843 RPS16 ribosomal protein S16 gene PW:0000101 translation pathway ISO RGD:737248 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18480843 RPS16 ribosomal protein S16 gene PW:0001066 ribosome biogenesis pathway ISO RGD:737248 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18481039 TPH1 tryptophan hydroxylase 1 gene PW:0000054 tryptophan metabolic pathway ISO RGD:735482 W RGD:9068941 20211008 SMPDB SMP:00063 18481207 GNAT1 G protein subunit alpha transducin 1 gene PW:0000962 visual phototransduction pathway ISO RGD:1312271 W RGD:9068941 20211008 RGD PMID:22074925|REF_RGD_ID:6893539 18481276 EGLN2 egl-9 family hypoxia inducible factor 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:631376 W RGD:9068941 20211008 RGD PMID:12876291|REF_RGD_ID:727754 18481276 EGLN2 egl-9 family hypoxia inducible factor 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:736328 W RGD:9068941 20211008 RGD PMID:14597660|PMID:15563310|REF_RGD_ID:1334463|REF_RGD_ID:1334466 18481276 EGLN2 egl-9 family hypoxia inducible factor 2 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:736328 W RGD:9068941 20211008 PID PID:200036 18481276 EGLN2 egl-9 family hypoxia inducible factor 2 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:736328 W RGD:9068941 20211008 RGD PMID:14597660|PMID:20396958|REF_RGD_ID:1334466|REF_RGD_ID:6483503 18481560 ABCD1 ATP binding cassette subfamily D member 1 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1352747 W RGD:9068941 20211008 SMPDB SMP:00052 18481560 ABCD1 ATP binding cassette subfamily D member 1 gene PW:0001705 Refsum disease pathway ISO RGD:1352747 W RGD:9068941 20211008 SMPDB SMP:00451 18481560 ABCD1 ATP binding cassette subfamily D member 1 gene PW:0002505 adrenoleukodystrophy pathway ISO RGD:1352747 W RGD:9068941 20211008 SMPDB SMP:00516 18481560 ABCD1 ATP binding cassette subfamily D member 1 gene PW:0002506 carnitine-acylcarnitine translocase deficiency ISO RGD:1352747 W RGD:9068941 20211008 SMPDB SMP:00517 18481560 ABCD1 ATP binding cassette subfamily D member 1 gene PW:0002564 phytanic acid degradation pathway ISO RGD:1352747 W RGD:9068941 20211008 SMPDB SMP:00450 18481632 RBM28 RNA binding motif protein 28 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1322736 W RGD:9068941 20211008 RGD PMID:23439679|REF_RGD_ID:9999449 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0000768 omeprazole pharmacokinetics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00613 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0000769 omeprazole pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00226 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001836 roxatidine acetate pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00734 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001845 ranitidine pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00230 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001847 rabeprazole pharmacokinetics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00616 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001848 rabeprazole pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00229 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001884 pirenzepine pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00246 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001889 pantoprazole pharmacokinetics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00615 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001890 pantoprazole pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00228 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001906 nizatidine pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00233 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001964 lansoprazole pharmacokinetics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00614 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0001965 lansoprazole pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00227 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0002039 famotidine pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00231 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0002112 cimetidine pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00232 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0002183 esomeprazole pharmacokinetics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00612 18481655 ATP4A ATPase H+/K+ transporting subunit alpha gene PW:0002184 esomeprazole pharmacodynamics pathway ISO RGD:734000 W RGD:9068941 20211008 SMPDB SMP:00225 18482670 FURIN furin, paired basic amino acid cleaving enzyme gene PW:0000204 Notch signaling pathway ISO RGD:1323167 W RGD:9068941 20211008 PID PID:200015 18482670 FURIN furin, paired basic amino acid cleaving enzyme gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1323167 W RGD:9068941 20211008 PID PID:200202 18482670 FURIN furin, paired basic amino acid cleaving enzyme gene PW:0000658 glypican signaling pathway ISO RGD:1323167 W RGD:9068941 20211008 PID PID:200225 18482819 SRSF10 serine and arginine rich splicing factor 10 gene PW:0001073 spliceosome pathway ISO RGD:1322327 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18482888 MLST8 MTOR associated protein, LST8 homolog gene PW:0000180 mTOR signaling pathway ISO RGD:736229 W RGD:9068941 20211008 PID PID:200096 18482888 MLST8 MTOR associated protein, LST8 homolog gene PW:0000180 mTOR signaling pathway ISO RGD:736229 W RGD:9068941 20211008 RGD PMID:12718876|PMID:19339977|PMID:22500797|REF_RGD_ID:11535033|REF_RGD_ID:1626104|REF_RGD_ID:2308795 18482888 MLST8 MTOR associated protein, LST8 homolog gene PW:0000232 phosphatidylinositol 3-kinase-Akt signaling pathway ISO RGD:736229 W RGD:9068941 20211008 PID PID:200197 18483010 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 gene PW:0001073 spliceosome pathway ISO RGD:1321287 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0000454 cholesterol biosynthetic pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00023 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0000728 statin pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00082|SMP:00089|SMP:00092|SMP:00099|SMP:00111|SMP:00119|SMP:00131 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0001586 Wolman disease pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00319|SMP:00511 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0001624 nitrogenous bisphosphonate pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00079|SMP:00095|SMP:00112|SMP:00117 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0001650 Smith-Lemli-Opitz Syndrome pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00389 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0001812 mevalonic aciduria pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00509|SMP:00510 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0001838 risedronate pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00112 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0001933 hypercholesterolemia pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00209 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002002 ibandronate pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00079 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002106 desmosterolosis pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00386 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002174 alendronate pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00095 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002177 pamidronate pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00117 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002270 zoledronate pharmacodynamics pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00107 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002347 cholesterol ester storage disease pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00508 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002439 congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00387 18483167 MSMO1 methylsterol monooxygenase 1 gene PW:0002591 X-linked dominant chondrodysplasia punctata 2 pathway ISO RGD:737148 W RGD:9068941 20211008 SMPDB SMP:00388 18483297 ARID1B AT-rich interaction domain 1B gene PW:0000626 pancreatic cancer pathway ISO RGD:1316702 W RGD:9068941 20211008 RGD PMID:23355908|REF_RGD_ID:8694154 18483297 ARID1B AT-rich interaction domain 1B gene PW:0001406 SWI/SNF family mediated chromatin remodeling pathway ISO RGD:1316702 W RGD:9068941 20211008 RGD PMID:21358755|PMID:23355908|REF_RGD_ID:8694154|REF_RGD_ID:9495920 18483297 ARID1B AT-rich interaction domain 1B gene PW:0001554 altered SWI/SNF family mediated chromatin remodeling pathway ISO RGD:1316702 W RGD:9068941 20211008 RGD PMID:23355908|REF_RGD_ID:8694154 18483391 RNF4 ring finger protein 4 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:737478 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18483391 RNF4 ring finger protein 4 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:737478 W RGD:9068941 20211008 RGD PMID:24002223|REF_RGD_ID:8661242 18483415 CASQ2 calsequestrin 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:737298 W RGD:9068941 20211008 RGD PMID:20356453|REF_RGD_ID:7204686 18483572 CHRNG cholinergic receptor nicotinic gamma subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:732695 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18483572 CHRNG cholinergic receptor nicotinic gamma subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:737384 W RGD:9068941 20211008 RGD PMID:23032192|REF_RGD_ID:8549508 18483630 FABP3 fatty acid binding protein 3 gene PW:0000286 integrin mediated signaling pathway ISO RGD:69087 W RGD:9068941 20211008 RGD PMID:23719537|REF_RGD_ID:7364738 18483748 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1309727 W RGD:9068941 20211008 RGD PMID:12024021|REF_RGD_ID:2302280 18483748 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1320222 W RGD:9068941 20211008 RGD PMID:17481747|REF_RGD_ID:2293891 18483748 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1320222 W RGD:9068941 20211008 RGD PMID:17726577|REF_RGD_ID:2293880 18483839 RBP2 retinol binding protein 2 gene PW:0000141 retinol metabolic pathway ISO RGD:734415 W RGD:9068941 20211008 RGD PMID:21718801|REF_RGD_ID:6484679 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00296 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00671 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:734096 W RGD:9068941 20211008 RGD PMID:20668007|REF_RGD_ID:7204681 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00379 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00431 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00413 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00665 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00376 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00375 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00659 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00660 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00323 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00307 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00402 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00324 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00686 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00380 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00381 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00382 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00366 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00687 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00691 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00302 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00408 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00399 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00378 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00422 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00332 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00426 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00331 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00415 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00301 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00425 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00325 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00359 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00423 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00424 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002134 bupranolol drug pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00670 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00670 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00300 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00299 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00296 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00684 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00393 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00298 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00305 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00401 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00404 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00303 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00306 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00688 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00326 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00666 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00327 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00329 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00416 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00662 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00397 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00409 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00410 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00411 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00412 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00394 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00663 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00681 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00395 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00328|SMP:00398 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00400 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00677 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00673 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00407 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00675 18483868 KCNIP2 potassium voltage-gated channel interacting protein 2 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:734096 W RGD:9068941 20211008 SMPDB SMP:00367 18483894 TFPT TCF3 fusion partner gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:733579 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18484052 GPX1 glutathione peroxidase 1 gene PW:0000134 glutathione metabolic pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00015 18484052 GPX1 glutathione peroxidase 1 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00075 18484052 GPX1 glutathione peroxidase 1 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00096 18484052 GPX1 glutathione peroxidase 1 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00086 18484052 GPX1 glutathione peroxidase 1 gene PW:0001524 paracetamol drug pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00710 18484052 GPX1 glutathione peroxidase 1 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00083 18484052 GPX1 glutathione peroxidase 1 gene PW:0001665 antipyrine drug pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00692 18484052 GPX1 glutathione peroxidase 1 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00116 18484052 GPX1 glutathione peroxidase 1 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00704 18484052 GPX1 glutathione peroxidase 1 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00706 18484052 GPX1 glutathione peroxidase 1 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00094 18484052 GPX1 glutathione peroxidase 1 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00077 18484052 GPX1 glutathione peroxidase 1 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00120 18484052 GPX1 glutathione peroxidase 1 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00114 18484052 GPX1 glutathione peroxidase 1 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00106 18484052 GPX1 glutathione peroxidase 1 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00109 18484052 GPX1 glutathione peroxidase 1 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00098 18484052 GPX1 glutathione peroxidase 1 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00085 18484052 GPX1 glutathione peroxidase 1 gene PW:0002019 glutathione synthase deficiency pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00143|SMP:00337 18484052 GPX1 glutathione peroxidase 1 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00084 18484052 GPX1 glutathione peroxidase 1 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00289 18484052 GPX1 glutathione peroxidase 1 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00093 18484052 GPX1 glutathione peroxidase 1 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00696 18484052 GPX1 glutathione peroxidase 1 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00104 18484052 GPX1 glutathione peroxidase 1 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00104 18484052 GPX1 glutathione peroxidase 1 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00700 18484052 GPX1 glutathione peroxidase 1 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00709 18484052 GPX1 glutathione peroxidase 1 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00708 18484052 GPX1 glutathione peroxidase 1 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00353 18484052 GPX1 glutathione peroxidase 1 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00705 18484052 GPX1 glutathione peroxidase 1 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00697 18484052 GPX1 glutathione peroxidase 1 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00698 18484052 GPX1 glutathione peroxidase 1 gene PW:0002562 glutathionuria disease pathway ISO RGD:737005 W RGD:9068941 20211008 SMPDB SMP:00501 18484165 PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 gene PW:0000046 inositol metabolic pathway ISO RGD:1323457 W RGD:9068941 20211008 SMPDB SMP:00011 18484165 PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 gene PW:0000278 autophagy pathway ISO RGD:1323457 W RGD:9068941 20211008 RGD PMID:20034776|REF_RGD_ID:4889529 18484165 PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:1323457 W RGD:9068941 20211008 SMPDB SMP:00463 18484189 VPS26B VPS26, retromer complex component B gene PW:0002430 retromer-mediated pathway ISO RGD:1603929 W RGD:9068941 20211008 RGD PMID:25619244|REF_RGD_ID:10450542 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00133 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00132 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00134 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001880 iminoglycinuria pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00193 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00105 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0001977 Hartnup disease pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00189 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00100 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00115 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00097 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00122 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00088 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00078 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00090 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002214 cystinuria pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00723 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00118 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00135 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00121 18484334 SLC7A7 solute carrier family 7 member 7 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:733448 W RGD:9068941 20211008 SMPDB SMP:00108 18484410 TOP2B DNA topoisomerase II beta gene PW:0001566 doxorubicin pharmacodynamics pathway ISO RGD:1350637 W RGD:9068941 20211008 RGD PMID:25895646|REF_RGD_ID:10395260 18484410 TOP2B DNA topoisomerase II beta gene PW:0001802 doxorubicin response pathway ISO RGD:1350637 W RGD:9068941 20211008 RGD PMID:24361676|PMID:25895646|REF_RGD_ID:10395260|REF_RGD_ID:10395267 18484410 TOP2B DNA topoisomerase II beta gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:1350637 W RGD:9068941 20211008 SMPDB SMP:00601 18484410 TOP2B DNA topoisomerase II beta gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:1350637 W RGD:9068941 20211008 SMPDB SMP:00442 18484510 PRPH2 peripherin 2 gene PW:0001497 retinitis pigmentosa pathway ISO RGD:735709 W RGD:9068941 20211008 RGD PMID:23701314|REF_RGD_ID:8547535 18484562 POLR3C RNA polymerase III subunit C gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1323060 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18484894 RNF20 ring finger protein 20 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1323649 W RGD:9068941 20211008 RGD PMID:23532176|REF_RGD_ID:8661225 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0000031 purine metabolic pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00050 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0000868 purine salvage pathway ISO RGD:731296 W RGD:9068941 20211008 RGD PMID:20005278|REF_RGD_ID:5135488 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001590 xanthinuria pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00220 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001591 xanthinuria type I pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00512 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001592 xanthinuria type II pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00513 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00210 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00537 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00203 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00364 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00365 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00609 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00428 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00427 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00167 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0002294 AICA-ribosuria pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00168 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0002393 tioguanine pharmacokinetics pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00647 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00430 18485130 HPRT1 hypoxanthine phosphoribosyltransferase 1 gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:731296 W RGD:9068941 20211008 SMPDB SMP:00535 18485208 SSH1 slingshot protein phosphatase 1 gene PW:0000159 Rab family mediated signaling pathway ISO RGD:1306038 W RGD:9068941 20211008 RGD PMID:20739464|REF_RGD_ID:10054052 18485208 SSH1 slingshot protein phosphatase 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1345208 W RGD:9068941 20211008 PID PID:200220 18485208 SSH1 slingshot protein phosphatase 1 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1306038 W RGD:9068941 20211008 RGD PMID:20739464|REF_RGD_ID:10054052 18485371 IMPA1 inositol monophosphatase 1 gene PW:0000046 inositol metabolic pathway ISO RGD:737559 W RGD:9068941 20211008 SMPDB SMP:00011 18485371 IMPA1 inositol monophosphatase 1 gene PW:0000154 inositol phosphate metabolic pathway ISO RGD:737559 W RGD:9068941 20211008 SMPDB SMP:00462 18485570 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1604217 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18485570 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase gene PW:0001842 mitochondrial autophagy pathway ISO RGD:1604217 W RGD:9068941 20211008 RGD PMID:25840011|REF_RGD_ID:10400888 18485650 POLR1D RNA polymerase I and III subunit D gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1343756 W RGD:9068941 20211008 RGD PMID:21893173|PMID:22365827|REF_RGD_ID:9588244|REF_RGD_ID:9588262 18485650 POLR1D RNA polymerase I and III subunit D gene PW:0000128 RNA polymerase III transcription pathway ISO RGD:1343756 W RGD:9068941 20211008 RGD PMID:12391170|PMID:20890107|REF_RGD_ID:9685217|REF_RGD_ID:9685218 18485855 ACSL4 acyl-CoA synthetase long chain family member 4 gene PW:0000738 fatty acid beta degradation pathway ISO RGD:1344693 W RGD:9068941 20211008 RGD PMID:17762044|REF_RGD_ID:2317576 18485873 RPL27A ribosomal protein L27a gene PW:0000101 translation pathway ISO RGD:1320286 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18485873 RPL27A ribosomal protein L27a gene PW:0001066 ribosome biogenesis pathway ISO RGD:1320286 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0000180 mTOR signaling pathway ISO RGD:620639 W RGD:9068941 20220224 RGD PMID:25049270|REF_RGD_ID:151361107 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001640 amiloride pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00133 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001792 triamterene pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00132 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001824 spironolactone pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00134 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001871 lysinuric protein intolerance pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00197|SMP:00585 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001880 iminoglycinuria pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00193 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001927 metolazone pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00105 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0001977 Hartnup disease pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00189 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002005 hydrochlorothiazide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00100 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002016 furosemide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00115 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002045 etacrynic acid pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00097 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002124 chlorthalidone pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00122 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002155 bumetanide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00088 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002188 chlorothiazide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00078 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002197 bendroflumethiazide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00090 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002214 cystinuria pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00723 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002252 torasemide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00118 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002273 eplerenone pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00135 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002322 trichlormethiazide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00121 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002379 hydroflumethiazide pharmacodynamics pathway ISO RGD:1354186 W RGD:9068941 20211008 SMPDB SMP:00108 18485944 SLC7A5 solute carrier family 7 member 5 gene PW:0002580 nicotinamide adenine dinucleotide metabolic pathway ISO RGD:1354186 W RGD:9068941 20211008 RGD PMID:25837229|REF_RGD_ID:11251687 18486025 MRE11 MRE11 homolog, double strand break repair nuclease gene PW:0000202 homologous recombination pathway of double-strand break repair ISO RGD:1344886 W RGD:9068941 20211008 RGD PMID:16498454|PMID:20690856|REF_RGD_ID:1578504|REF_RGD_ID:8662366 18486025 MRE11 MRE11 homolog, double strand break repair nuclease gene PW:0000720 altered p53 signaling pathway ISO RGD:1344886 W RGD:9068941 20211008 RGD PMID:23263379|REF_RGD_ID:8663431 18486025 MRE11 MRE11 homolog, double strand break repair nuclease gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1344886 W RGD:9068941 20211008 RGD PMID:21533982|REF_RGD_ID:8661232 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00296 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00379 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00665 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00376 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00375 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00659 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00660 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00323 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00307 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00324 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00380 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00381 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00382 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00366 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00302 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00378 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00332 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00331 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00301 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00325 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00359 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002134 bupranolol drug pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00670 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00670 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00300 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00299 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00296 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00298 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00305 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00303 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00306 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00326 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00666 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00327 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00329 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00662 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00663 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00328 18486243 KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:731917 W RGD:9068941 20211008 SMPDB SMP:00367 18486409 CYP3A43 cytochrome P450 family 3 subfamily A member 43 gene PW:0000141 retinol metabolic pathway ISO RGD:1350489 W RGD:9068941 20211008 SMPDB SMP:00074 18486409 CYP3A43 cytochrome P450 family 3 subfamily A member 43 gene PW:0001585 vitamin A deficiency pathway ISO RGD:1350489 W RGD:9068941 20211008 SMPDB SMP:00336 18486444 VAC14 VAC14 component of PIKFYVE complex gene PW:0000046 inositol metabolic pathway ISO RGD:1347283 W RGD:9068941 20211008 SMPDB SMP:00011 18486444 VAC14 VAC14 component of PIKFYVE complex gene PW:0002418 phosphoinositide metabolic pathway ISO RGD:1347283 W RGD:9068941 20211008 SMPDB SMP:00463 18486832 NCL nucleolin gene PW:0000126 RNA polymerase I transcription pathway ISO RGD:1342988 W RGD:9068941 20211008 RGD PMID:21893173|PMID:25225127|REF_RGD_ID:9588244|REF_RGD_ID:9588251 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0000058 fatty acid metabolic pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00051 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0000071 valine, leucine and isoleucine degradation pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00032 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001452 valproic acid pharmacokinetics pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00635 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001594 very long-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00540 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001627 trifunctional protein deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00545 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001667 short-chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00235 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001778 propionic acidemia pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00236 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001809 methylmalonate semialdehyde dehydrogenase deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00384 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001810 methylmalonic acidemia pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00200 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001869 medium chain acyl-CoA dehydrogenase deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00542 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001870 maple syrup urine disease pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00199 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001874 isovaleric acidemia pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00238|SMP:00524 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0001875 isobutyryl-CoA dehydrogenase deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00523 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002206 ethylmalonic encephalopathy pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00181 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002274 3-methylglutaconic aciduria type 1 pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00139 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002275 3-methylglutaconic aciduria type 3 pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00140 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002306 glutaric aciduria type I pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00185 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002323 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00138 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002569 3-hydroxyisobutyric aciduria pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00521|SMP:00522 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002574 carnitine palmitoyltransferase I deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00538 18486931 ACADSB acyl-CoA dehydrogenase short/branched chain gene PW:0002576 3-methylcrotonyl CoA carboxylase 1 deficiency pathway ISO RGD:735869 W RGD:9068941 20211008 SMPDB SMP:00237 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0000141 retinol metabolic pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00074 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00648 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001225 irinotecan pharmacokinetics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00600 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001226 irinotecan pharmacodynamics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00433 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001245 codeine and morphine pharmacokinetics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00622 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00406 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00590 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00086 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00640 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0001585 vitamin A deficiency pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00336 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00327 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00601 18487043 ERP29 endoplasmic reticulum protein 29 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:735473 W RGD:9068941 20211008 SMPDB SMP:00442 18487080 XAB2 XPA binding protein 2 gene PW:0000130 nucleotide excision repair pathway ISO RGD:1342496 W RGD:9068941 20211008 RGD PMID:22824526|REF_RGD_ID:7246919 18487080 XAB2 XPA binding protein 2 gene PW:0001073 spliceosome pathway ISO RGD:1342496 W RGD:9068941 20211008 RGD PMID:23742842|REF_RGD_ID:9686094 18487103 KMT2B lysine methyltransferase 2B gene PW:0001338 histone modification pathway ISO RGD:1605411 W RGD:9068941 20211008 RGD PMID:22663077|PMID:23200123|REF_RGD_ID:7242632|REF_RGD_ID:9479053 18487173 LHB luteinizing hormone subunit beta gene PW:0001070 luteinizing hormone signaling pathway ISO RGD:69097 W RGD:9068941 20211008 SMPDB SMP:00338 18487190 AQP4 aquaporin 4 gene PW:0000419 water transport pathway ISO RGD:10183 W RGD:9068941 20211008 RGD PMID:19096774|REF_RGD_ID:2312795 18487190 AQP4 aquaporin 4 gene PW:0000419 water transport pathway ISO RGD:735519 W RGD:9068941 20211008 RGD PMID:19096774|REF_RGD_ID:2312795 18487264 GLUL glutamate-ammonia ligase gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:2710 W RGD:9068941 20211008 RGD PMID:28323|PMID:4403443|REF_RGD_ID:2301547|REF_RGD_ID:2301548 18487264 GLUL glutamate-ammonia ligase gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:730955 W RGD:9068941 20211008 SMPDB SMP:00072 18487264 GLUL glutamate-ammonia ligase gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:730955 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18487264 GLUL glutamate-ammonia ligase gene PW:0001979 homocarnosinosis pathway ISO RGD:730955 W RGD:9068941 20211008 SMPDB SMP:00385 18487264 GLUL glutamate-ammonia ligase gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:730955 W RGD:9068941 20211008 SMPDB SMP:00136 18487568 IL10RA interleukin 10 receptor subunit alpha gene PW:0000515 Interleukin-10 signaling pathway ISO RGD:620138 W RGD:9068941 20211008 RGD PMID:19428551|REF_RGD_ID:2311043 18487568 IL10RA interleukin 10 receptor subunit alpha gene PW:0000515 Interleukin-10 signaling pathway ISO RGD:731000 W RGD:9068941 20211008 RGD PMID:21115385|REF_RGD_ID:5688379 18487666 FARSA phenylalanyl-tRNA synthetase subunit alpha gene PW:0001609 tyrosinemia type II pathway ISO RGD:1321146 W RGD:9068941 20211008 SMPDB SMP:00369 18487666 FARSA phenylalanyl-tRNA synthetase subunit alpha gene PW:0001610 tyrosinemia type III pathway ISO RGD:1321146 W RGD:9068941 20211008 SMPDB SMP:00370 18487666 FARSA phenylalanyl-tRNA synthetase subunit alpha gene PW:0001805 phenylketonuria pathway ISO RGD:1321146 W RGD:9068941 20211008 SMPDB SMP:00206 18487772 ATP2B4 ATPase plasma membrane Ca2+ transporting 4 gene PW:0001139 calcium transport pathway ISO RGD:1348952 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18487772 ATP2B4 ATPase plasma membrane Ca2+ transporting 4 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1348952 W RGD:9068941 20211008 RGD PMID:19789383|REF_RGD_ID:7204695 18487839 CNOT3 CCR4-NOT transcription complex subunit 3 gene PW:0000808 microRNA pathway ISO RGD:1312407 W RGD:9068941 20211008 RGD PMID:23337855|REF_RGD_ID:9850101 18487874 SH2D2A SH2 domain containing 2A gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1345635 W RGD:9068941 20211008 PID PID:200188 18487874 SH2D2A SH2 domain containing 2A gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:1345635 W RGD:9068941 20211008 RGD PMID:17658244|REF_RGD_ID:2298729 18487874 SH2D2A SH2 domain containing 2A gene PW:0000603 Erk5 MAPK signaling pathway ISO RGD:1345635 W RGD:9068941 20211008 RGD PMID:16376520|REF_RGD_ID:2298532 18488042 PRPF4 pre-mRNA splicing tri-snRNP complex factor PRPF4 gene PW:0001073 spliceosome pathway ISO RGD:1322687 W RGD:9068941 20211008 RGD PMID:19239890|REF_RGD_ID:9686089 18488191 EFNA2 ephrin A2 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1314277 W RGD:9068941 20211008 PID PID:200142 18488191 EFNA2 ephrin A2 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:620389 W RGD:9068941 20211008 RGD PMID:10792438|REF_RGD_ID:1300471 18488347 CRH corticotropin releasing hormone gene PW:0000493 corticotropin-releasing hormone signaling pathway ISO RGD:620505 W RGD:9068941 20211008 RGD PMID:12942143|REF_RGD_ID:1358326 18488347 CRH corticotropin releasing hormone gene PW:0000493 corticotropin-releasing hormone signaling pathway ISO RGD:730946 W RGD:9068941 20211008 RGD PMID:16484629|REF_RGD_ID:5147387 18488353 ESPN espin gene PW:0001503 auditory mechanotransduction pathway ISO RGD:731924 W RGD:9068941 20211008 RGD PMID:19804752|PMID:20624897|REF_RGD_ID:8547667|REF_RGD_ID:8547669 18488423 TMLHE trimethyllysine hydroxylase, epsilon gene PW:0002292 carnitine biosynthetic pathway ISO RGD:736195 W RGD:9068941 20211008 SMPDB SMP:00465 18488507 ATP7B ATPase copper transporting beta gene PW:0001508 cisplatin drug pathway ISO RGD:731392 W RGD:9068941 20211008 RGD PMID:22796517|REF_RGD_ID:8548473 18488586 OAZ1 ornithine decarboxylase antizyme 1 gene PW:0000214 polyamine metabolic pathway ISO RGD:733111 W RGD:9068941 20211008 RGD PMID:21849468|REF_RGD_ID:7244195 18488791 SOD1 superoxide dismutase 1 gene PW:0000016 amyotrophic lateral sclerosis pathway ISO RGD:11329 W RGD:9068941 20211008 RGD PMID:16583367|REF_RGD_ID:1581209 18488791 SOD1 superoxide dismutase 1 gene PW:0000016 amyotrophic lateral sclerosis pathway ISO RGD:730855 W RGD:9068941 20211008 RGD PMID:8446170|REF_RGD_ID:737689 18488791 SOD1 superoxide dismutase 1 gene PW:0000021 hypertension pathway ISO RGD:3731 W RGD:9068941 20211008 RGD PMID:16716903|REF_RGD_ID:1580833 18488791 SOD1 superoxide dismutase 1 gene PW:0000021 hypertension pathway ISO RGD:730855 W RGD:9068941 20211008 RGD PMID:16716903|REF_RGD_ID:1580833 18488791 SOD1 superoxide dismutase 1 gene PW:0000958 forkhead class A signaling pathway ISO RGD:730855 W RGD:9068941 20211008 PID PID:200226 18488831 GAL3ST1 galactose-3-O-sulfotransferase 1 gene PW:0000197 sphingolipid metabolic pathway ISO RGD:1350287 W RGD:9068941 20211008 SMPDB SMP:00034 18488831 GAL3ST1 galactose-3-O-sulfotransferase 1 gene PW:0001454 Gaucher's disease pathway ISO RGD:1350287 W RGD:9068941 20211008 SMPDB SMP:00349 18488831 GAL3ST1 galactose-3-O-sulfotransferase 1 gene PW:0002021 Krabbe disease pathway ISO RGD:1350287 W RGD:9068941 20211008 SMPDB SMP:00348 18488831 GAL3ST1 galactose-3-O-sulfotransferase 1 gene PW:0002103 Fabry disease pathway ISO RGD:1350287 W RGD:9068941 20211008 SMPDB SMP:00525 18488831 GAL3ST1 galactose-3-O-sulfotransferase 1 gene PW:0002532 metachromatic leukodystrophy pathway ISO RGD:1350287 W RGD:9068941 20211008 SMPDB SMP:00347 18488886 HSPG2 heparan sulfate proteoglycan 2 gene PW:0000122 Hedgehog signaling pathway ISO RGD:621770 W RGD:9068941 20211008 RGD PMID:21720682|REF_RGD_ID:5510033 18489594 CCNA2 cyclin A2 gene PW:0000088 G1/S transition pathway ISO RGD:1348754 W RGD:9068941 20211008 RGD PMID:10919634|PMID:16236519|REF_RGD_ID:8694143|REF_RGD_ID:8694150 18489594 CCNA2 cyclin A2 gene PW:0000718 p53 signaling pathway ISO RGD:1348754 W RGD:9068941 20211008 PID PID:200206 18489663 RIOK3 RIO kinase 3 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1321961 W RGD:9068941 20211008 RGD PMID:24424021|REF_RGD_ID:10002751 18490053 RPL14 ribosomal protein L14 gene PW:0000101 translation pathway ISO RGD:733020 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18490053 RPL14 ribosomal protein L14 gene PW:0001066 ribosome biogenesis pathway ISO RGD:733020 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18490210 WARS1 tryptophanyl-tRNA synthetase 1 gene PW:0000054 tryptophan metabolic pathway ISO RGD:1317961 W RGD:9068941 20211008 SMPDB SMP:00063 18490326 CACNA1B calcium voltage-gated channel subunit alpha1 B gene PW:0001139 calcium transport pathway ISO RGD:1347795 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18490326 CACNA1B calcium voltage-gated channel subunit alpha1 B gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:1347795 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18490400 PTGES prostaglandin E synthase gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00075 18490400 PTGES prostaglandin E synthase gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00096 18490400 PTGES prostaglandin E synthase gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00086 18490400 PTGES prostaglandin E synthase gene PW:0001524 paracetamol drug pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00710 18490400 PTGES prostaglandin E synthase gene PW:0001532 prostaglandin biosynthetic pathway ISO RGD:69032 W RGD:9068941 20211008 RGD PMID:22679221|PMID:23063076|REF_RGD_ID:8552701|REF_RGD_ID:8552712 18490400 PTGES prostaglandin E synthase gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00083 18490400 PTGES prostaglandin E synthase gene PW:0001665 antipyrine drug pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00692 18490400 PTGES prostaglandin E synthase gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00116 18490400 PTGES prostaglandin E synthase gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00704 18490400 PTGES prostaglandin E synthase gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00706 18490400 PTGES prostaglandin E synthase gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00094 18490400 PTGES prostaglandin E synthase gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00077 18490400 PTGES prostaglandin E synthase gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00120 18490400 PTGES prostaglandin E synthase gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00114 18490400 PTGES prostaglandin E synthase gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00106 18490400 PTGES prostaglandin E synthase gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00109 18490400 PTGES prostaglandin E synthase gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00098 18490400 PTGES prostaglandin E synthase gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00085 18490400 PTGES prostaglandin E synthase gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00084 18490400 PTGES prostaglandin E synthase gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00289 18490400 PTGES prostaglandin E synthase gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00093 18490400 PTGES prostaglandin E synthase gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00696 18490400 PTGES prostaglandin E synthase gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00104 18490400 PTGES prostaglandin E synthase gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00104 18490400 PTGES prostaglandin E synthase gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00700 18490400 PTGES prostaglandin E synthase gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00709 18490400 PTGES prostaglandin E synthase gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00708 18490400 PTGES prostaglandin E synthase gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00353 18490400 PTGES prostaglandin E synthase gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00705 18490400 PTGES prostaglandin E synthase gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00697 18490400 PTGES prostaglandin E synthase gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:69032 W RGD:9068941 20211008 SMPDB SMP:00698 18490407 USP12 ubiquitin specific peptidase 12 gene PW:0001338 histone modification pathway ISO RGD:1317587 W RGD:9068941 20211008 RGD PMID:24647359|REF_RGD_ID:9479061 18490526 TUT7 terminal uridylyl transferase 7 gene PW:0000808 microRNA pathway ISO RGD:1344359 W RGD:9068941 20211008 RGD PMID:23622238|REF_RGD_ID:9850106 18490699 GLRA1 glycine receptor alpha 1 gene PW:0000456 Inhibitory synaptic transmission pathway ISO RGD:2704 W RGD:9068941 20211008 RGD PMID:14749434|REF_RGD_ID:1598573 18490730 GATA3 GATA binding protein 3 gene PW:0000204 Notch signaling pathway ISO RGD:733638 W RGD:9068941 20211008 PID PID:200015 18490730 GATA3 GATA binding protein 3 gene PW:0000916 interleukin-27 signaling pathway ISO RGD:733638 W RGD:9068941 20211008 PID PID:200028 18491039 MAP3K14 mitogen-activated protein kinase kinase kinase 14 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1321416 W RGD:9068941 20211008 PID PID:200048 18491039 MAP3K14 mitogen-activated protein kinase kinase kinase 14 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1321416 W RGD:9068941 20211008 RGD PMID:18267068|REF_RGD_ID:2292172 18491078 SERPING1 serpin family G member 1 gene PW:0000474 coagulation cascade pathway ISO RGD:1344082 W RGD:9068941 20211008 RGD PMID:12787532|PMID:26018600|REF_RGD_ID:11342779|REF_RGD_ID:11352277 18491078 SERPING1 serpin family G member 1 gene PW:0000526 kallikrein-kinin cascade pathway ISO RGD:1344082 W RGD:9068941 20211008 RGD PMID:16177542|REF_RGD_ID:7401223 18491159 EDN2 endothelin 2 gene PW:0000506 endothelin signaling pathway ISO RGD:737548 W RGD:9068941 20211008 PID PID:200005 18491263 DGUOK deoxyguanosine kinase gene PW:0000031 purine metabolic pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00050 18491263 DGUOK deoxyguanosine kinase gene PW:0001590 xanthinuria pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00220 18491263 DGUOK deoxyguanosine kinase gene PW:0001591 xanthinuria type I pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00512 18491263 DGUOK deoxyguanosine kinase gene PW:0001592 xanthinuria type II pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00513 18491263 DGUOK deoxyguanosine kinase gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00210 18491263 DGUOK deoxyguanosine kinase gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00537 18491263 DGUOK deoxyguanosine kinase gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00203 18491263 DGUOK deoxyguanosine kinase gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00364 18491263 DGUOK deoxyguanosine kinase gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00365 18491263 DGUOK deoxyguanosine kinase gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00428 18491263 DGUOK deoxyguanosine kinase gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00427 18491263 DGUOK deoxyguanosine kinase gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00167 18491263 DGUOK deoxyguanosine kinase gene PW:0002294 AICA-ribosuria pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00168 18491263 DGUOK deoxyguanosine kinase gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00430 18491263 DGUOK deoxyguanosine kinase gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:1312453 W RGD:9068941 20211008 SMPDB SMP:00535 18491381 UPB1 beta-ureidopropionase 1 gene PW:0000032 pyrimidine metabolic pathway ISO RGD:620091 W RGD:9068941 20211008 RGD PMID:7626590|REF_RGD_ID:1624989 18491381 UPB1 beta-ureidopropionase 1 gene PW:0000032 pyrimidine metabolic pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00046 18491381 UPB1 beta-ureidopropionase 1 gene PW:0000077 beta-alanine metabolic pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00007 18491381 UPB1 beta-ureidopropionase 1 gene PW:0001603 beta-ureidopropionase deficiency pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00172 18491381 UPB1 beta-ureidopropionase 1 gene PW:0001605 orotic aciduria 1 pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00219 18491381 UPB1 beta-ureidopropionase 1 gene PW:0002095 GABA aminotransferase deficiency pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00351 18491381 UPB1 beta-ureidopropionase 1 gene PW:0002211 dihydropyrimidinase deficiency pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00178 18491381 UPB1 beta-ureidopropionase 1 gene PW:0002365 mitochondrial neurogastrointestinal encephalopathy syndrome pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00202 18491381 UPB1 beta-ureidopropionase 1 gene PW:0002565 carnosinemia pathway ISO RGD:734439 W RGD:9068941 20211008 SMPDB SMP:00493 18491502 SERPINA4 serpin family A member 4 gene PW:0000526 kallikrein-kinin cascade pathway ISO RGD:1348774 W RGD:9068941 20211008 RGD PMID:16177542|REF_RGD_ID:7401223 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0000725 potassium channel inhibitors pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00453|SMP:00454 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00296 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001100 tramadol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00671 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001246 codeine and morphine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00405|SMP:00406 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00379 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001450 nicotine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00431 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001634 alfentanil pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00413 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00665 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00376 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00375 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00659 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00660 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00323 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00307 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001857 procaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00402 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00324 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001887 pentazocine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00686 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00380 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00381 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00382 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00366 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001918 naltrexone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00687 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001921 nalbuphine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00691 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00302 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00408 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001947 mepivacaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00399 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00378 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001987 imipramine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00422 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00332 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002008 gliclazide pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00461 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002011 glyburide pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00460 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002030 fluoxetine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00426 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00331 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002036 fentanyl pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00415 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00301 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002051 escitalopram pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00425 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00325 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00359 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002090 desipramine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00423 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002118 citalopram pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00424 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002134 bupranolol drug pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00670 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00670 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00300 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00299 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00296 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002191 buprenorphine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00684 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002194 bupivacaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00393 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00298 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00305 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002246 prilocaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00401 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002249 ropivacaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00404 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00303 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00306 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002284 naloxone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00688 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00326 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00666 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00327 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00329 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002363 remifentanil pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00416 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00662 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002442 levobupivacaine phgarmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00397 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002446 oxycodone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00409 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002449 hydromorphone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00410 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002452 hydrocodone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00411 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002455 oxymorphone pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00412 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002469 felodipine pharmacokinetics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00619 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002484 chloroprocaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00394 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00663 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002527 ethylmorphine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00681 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002535 cocaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00395 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00328|SMP:00398 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002541 oxybuprocaine pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00400 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002553 levacetylmethadol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00677 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002556 levorphanol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00673 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002560 heroin pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00407 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002572 diphenoxylate pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00675 18491546 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:737609 W RGD:9068941 20211008 SMPDB SMP:00367 18491659 FBLIM1 filamin binding LIM protein 1 gene PW:0000286 integrin mediated signaling pathway ISO RGD:1606792 W RGD:9068941 20211008 RGD PMID:23860236|REF_RGD_ID:7349373 18491774 EFTUD2 elongation factor Tu GTP binding domain containing 2 gene PW:0001073 spliceosome pathway ISO RGD:1606577 W RGD:9068941 20211008 RGD PMID:23454554|PMID:23592432|REF_RGD_ID:9686090|REF_RGD_ID:9686093 18491816 SKP1 S-phase kinase associated protein 1 gene PW:0000204 Notch signaling pathway ISO RGD:1347276 W RGD:9068941 20211008 PID PID:200015 18491816 SKP1 S-phase kinase associated protein 1 gene PW:0000369 nuclear factor, erythroid 2 like 2 signaling pathway ISO RGD:1347276 W RGD:9068941 20211008 RGD PMID:24647116|REF_RGD_ID:11535066 18491816 SKP1 S-phase kinase associated protein 1 gene PW:0000499 nuclear factor kappa B signaling pathway ISO RGD:1347276 W RGD:9068941 20211008 RGD PMID:21135871|REF_RGD_ID:5490225 18491921 PCNA proliferating cell nuclear antigen gene PW:0000130 nucleotide excision repair pathway ISO RGD:732094 W RGD:9068941 20211008 RGD PMID:17512402|PMID:23545418|REF_RGD_ID:7246931|REF_RGD_ID:7246932 18491921 PCNA proliferating cell nuclear antigen gene PW:0000130 nucleotide excision repair pathway ISO RGD:732094 W RGD:9068941 20211008 SMPDB SMP:00478 18491921 PCNA proliferating cell nuclear antigen gene PW:0000662 mismatch repair pathway ISO RGD:732094 W RGD:9068941 20211008 RGD PMID:18157157|REF_RGD_ID:2306716 18491950 SNTB1 syntrophin beta 1 gene PW:0000801 adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00296 18491950 SNTB1 syntrophin beta 1 gene PW:0001249 nifedipine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00379 18491950 SNTB1 syntrophin beta 1 gene PW:0001658 amiodarone pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00665 18491950 SNTB1 syntrophin beta 1 gene PW:0001661 amlodipine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00376 18491950 SNTB1 syntrophin beta 1 gene PW:0001687 verapamil pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00375 18491950 SNTB1 syntrophin beta 1 gene PW:0001741 timolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00659 18491950 SNTB1 syntrophin beta 1 gene PW:0001829 sotalol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00660 18491950 SNTB1 syntrophin beta 1 gene PW:0001851 quinidine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00323 18491950 SNTB1 syntrophin beta 1 gene PW:0001854 propranolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00307 18491950 SNTB1 syntrophin beta 1 gene PW:0001860 procainamide pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00324 18491950 SNTB1 syntrophin beta 1 gene PW:0001901 nimodipine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00380 18491950 SNTB1 syntrophin beta 1 gene PW:0001902 nisoldipine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00381 18491950 SNTB1 syntrophin beta 1 gene PW:0001903 nitrendipine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00382 18491950 SNTB1 syntrophin beta 1 gene PW:0001912 nebivolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00366 18491950 SNTB1 syntrophin beta 1 gene PW:0001930 metoprolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00302 18491950 SNTB1 syntrophin beta 1 gene PW:0001974 isradipine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00378 18491950 SNTB1 syntrophin beta 1 gene PW:0001990 ibutilide pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00332 18491950 SNTB1 syntrophin beta 1 gene PW:0002033 flecainde pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00331 18491950 SNTB1 syntrophin beta 1 gene PW:0002048 esmolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00301 18491950 SNTB1 syntrophin beta 1 gene PW:0002068 disopyramide pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00325 18491950 SNTB1 syntrophin beta 1 gene PW:0002078 diltiazem pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00359 18491950 SNTB1 syntrophin beta 1 gene PW:0002134 bupranolol drug pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00670 18491950 SNTB1 syntrophin beta 1 gene PW:0002136 bupranolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00670 18491950 SNTB1 syntrophin beta 1 gene PW:0002158 bisoprolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00300 18491950 SNTB1 syntrophin beta 1 gene PW:0002162 betaxolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00299 18491950 SNTB1 syntrophin beta 1 gene PW:0002171 acebutolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00296 18491950 SNTB1 syntrophin beta 1 gene PW:0002232 atenolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00298 18491950 SNTB1 syntrophin beta 1 gene PW:0002239 penbutolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00305 18491950 SNTB1 syntrophin beta 1 gene PW:0002261 nadolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00303 18491950 SNTB1 syntrophin beta 1 gene PW:0002264 pindolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00306 18491950 SNTB1 syntrophin beta 1 gene PW:0002297 fosphenytoin pharmacokinetics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00618 18491950 SNTB1 syntrophin beta 1 gene PW:0002298 fosphenytoin pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00326 18491950 SNTB1 syntrophin beta 1 gene PW:0002309 levobunolol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00666 18491950 SNTB1 syntrophin beta 1 gene PW:0002335 phenytoin pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00327 18491950 SNTB1 syntrophin beta 1 gene PW:0002339 mexiletine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00329 18491950 SNTB1 syntrophin beta 1 gene PW:0002384 dobutamine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00662 18491950 SNTB1 syntrophin beta 1 gene PW:0002503 isoprenaline pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00663 18491950 SNTB1 syntrophin beta 1 gene PW:0002538 lidocaine pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00328 18491950 SNTB1 syntrophin beta 1 gene PW:0002587 carvedilol pharmacodynamics pathway ISO RGD:1317088 W RGD:9068941 20211008 SMPDB SMP:00367 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00075 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0000461 cyclooxygenase mediated pathway of arachidonic acid metabolism ISO RGD:736739 W RGD:9068941 20211008 RGD PMID:22679221|PMID:23063076|REF_RGD_ID:8552701|REF_RGD_ID:8552712 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0000762 celecoxib pharmacokinetics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00644 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00096 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001243 prostanoid biosynthetic pathway ISO RGD:736739 W RGD:9068941 20211008 RGD PMID:22679221|PMID:23063076|REF_RGD_ID:8552701|REF_RGD_ID:8552712 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00590 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00086 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001524 paracetamol drug pathway ISO RGD:736739 W RGD:9068941 20211008 RGD PMID:23719833|REF_RGD_ID:8552695 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001524 paracetamol drug pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00710 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00083 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001665 antipyrine drug pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00692 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00116 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00704 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00706 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00094 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00077 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00120 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00114 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00106 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00109 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00098 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00085 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00084 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00289 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00093 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00696 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00104 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00104 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002345 etoposide pharmacokinetics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00601 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002346 etoposide pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00442 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00700 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00709 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00708 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00353 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00705 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00697 18491962 PTGS1 prostaglandin-endoperoxide synthase 1 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:736739 W RGD:9068941 20211008 SMPDB SMP:00698 18492052 PEBP1 phosphatidylethanolamine binding protein 1 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:62017 W RGD:9068941 20211008 RGD PMID:10490027|PMID:17126425|REF_RGD_ID:2293882|REF_RGD_ID:2302807 18492167 ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 gene PW:0000388 Reelin signaling pathway ISO RGD:1312226 W RGD:9068941 20211008 PID PID:200062 18492337 TIMM10 translocase of inner mitochondrial membrane 10 gene PW:0002138 carrier pathway of mitochondrial protein import ISO RGD:734114 W RGD:9068941 20211008 RGD PMID:14726512|REF_RGD_ID:10412667 18492337 TIMM10 translocase of inner mitochondrial membrane 10 gene PW:0002140 beta-barrel pathway of mitochondrial protein import ISO RGD:734114 W RGD:9068941 20211008 RGD PMID:25305573|REF_RGD_ID:10412662 18492380 LYPLA1 lysophospholipase 1 gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:735384 W RGD:9068941 20211008 SMPDB SMP:00025 18492496 SF3A2 splicing factor 3a subunit 2 gene PW:0001073 spliceosome pathway ISO RGD:1318510 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18492767 LOC103214855 growth arrest-specific protein 6 gene PW:0000495 Gas6 - Axl signaling axis ISO RGD:61913 W RGD:9068941 20211008 RGD PMID:16285961|REF_RGD_ID:1579881 18492883 CHRNB4 cholinergic receptor nicotinic beta 4 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:732764 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18492978 PDGFB platelet derived growth factor subunit B gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:737124 W RGD:9068941 20211008 PID PID:200149|PID:200201 18492978 PDGFB platelet derived growth factor subunit B gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:737124 W RGD:9068941 20211008 PID PID:200046|PID:200085 18493133 NCOA1 nuclear receptor coactivator 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1319167 W RGD:9068941 20211008 PID PID:200202 18493133 NCOA1 nuclear receptor coactivator 1 gene PW:0000507 estrogen signaling pathway ISO RGD:1319167 W RGD:9068941 20211008 RGD PMID:16394250|REF_RGD_ID:5128512 18493133 NCOA1 nuclear receptor coactivator 1 gene PW:0000564 androgen signaling pathway ISO RGD:1319167 W RGD:9068941 20211008 RGD PMID:17163421|REF_RGD_ID:2326123 18493133 NCOA1 nuclear receptor coactivator 1 gene PW:0000568 aldosterone signaling pathway ISO RGD:1319167 W RGD:9068941 20211008 RGD PMID:21784126|REF_RGD_ID:7421504 18493133 NCOA1 nuclear receptor coactivator 1 gene PW:0000569 cortisol signaling pathway ISO RGD:1319167 W RGD:9068941 20211008 RGD PMID:11306337|PMID:19818358|REF_RGD_ID:5144138|REF_RGD_ID:5147892 18493133 NCOA1 nuclear receptor coactivator 1 gene PW:0001014 retinoic acid signaling pathway ISO RGD:1319167 W RGD:9068941 20211008 RGD PMID:19471584|REF_RGD_ID:6484676 18493322 ITCH itchy E3 ubiquitin protein ligase gene PW:0000204 Notch signaling pathway ISO RGD:1343086 W RGD:9068941 20211008 PID PID:200015 18493322 ITCH itchy E3 ubiquitin protein ligase gene PW:0000233 tumor necrosis factor mediated signaling pathway ISO RGD:1343086 W RGD:9068941 20211008 RGD PMID:21119682|PMID:23312890|REF_RGD_ID:7800734|REF_RGD_ID:7800735 18493322 ITCH itchy E3 ubiquitin protein ligase gene PW:0000490 transforming growth factor-beta Smad dependent signaling pathway ISO RGD:1343086 W RGD:9068941 20211008 PID PID:200227 18493353 PHGDH phosphoglycerate dehydrogenase gene PW:0001670 sarcosinemia pathway ISO RGD:737224 W RGD:9068941 20211008 SMPDB SMP:00244 18493353 PHGDH phosphoglycerate dehydrogenase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:737224 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18493353 PHGDH phosphoglycerate dehydrogenase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:737224 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18493353 PHGDH phosphoglycerate dehydrogenase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:737224 W RGD:9068941 20211008 SMPDB SMP:00179 18493369 SPIN1 spindlin 1 gene PW:0001338 histone modification pathway ISO RGD:1314698 W RGD:9068941 20211008 RGD PMID:24035451|REF_RGD_ID:9479148 18493468 CSNK1D casein kinase 1 delta gene PW:0000122 Hedgehog signaling pathway ISO RGD:733311 W RGD:9068941 20211008 PID PID:200172 18493468 CSNK1D casein kinase 1 delta gene PW:0000718 p53 signaling pathway ISO RGD:733311 W RGD:9068941 20211008 PID PID:200206 18493468 CSNK1D casein kinase 1 delta gene PW:0001066 ribosome biogenesis pathway ISO RGD:733311 W RGD:9068941 20211008 RGD PMID:24424021|REF_RGD_ID:10002751 18493494 NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 gene PW:0000034 electron transport chain pathway ISO RGD:1350497 W RGD:9068941 20211008 SMPDB SMP:00355 18493905 APH1B aph-1 homolog B, gamma-secretase subunit gene PW:0000204 Notch signaling pathway ISO RGD:1344589 W RGD:9068941 20211008 PID PID:200015 18493905 APH1B aph-1 homolog B, gamma-secretase subunit gene PW:0000204 Notch signaling pathway ISO RGD:1344589 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18493905 APH1B aph-1 homolog B, gamma-secretase subunit gene PW:0000659 syndecan signaling pathway ISO RGD:1344589 W RGD:9068941 20211008 PID PID:200198 18493970 MYOCD myocardin gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1344327 W RGD:9068941 20211008 PID PID:200149 18494059 CTNND1 catenin delta 1 gene PW:0000328 fibroblast growth factor signaling pathway ISO RGD:1313793 W RGD:9068941 20211008 PID PID:200220 18494059 CTNND1 catenin delta 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1313793 W RGD:9068941 20211008 PID PID:200124|PID:200147|PID:200182 18494059 CTNND1 catenin delta 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:1313793 W RGD:9068941 20211008 PID PID:200209 18494334 TAOK3 TAO kinase 3 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1605388 W RGD:9068941 20211008 PID PID:200018 18494411 RPL35A ribosomal protein L35a gene PW:0000101 translation pathway ISO RGD:733438 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18494411 RPL35A ribosomal protein L35a gene PW:0001066 ribosome biogenesis pathway ISO RGD:733438 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18494431 KDM8 lysine demethylase 8 gene PW:0001338 histone modification pathway ISO RGD:1602684 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18494502 TLR6 toll like receptor 6 gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1303030 W RGD:9068941 20211008 RGD PMID:16973131|PMID:18353287|REF_RGD_ID:1643119|REF_RGD_ID:5684896 18494502 TLR6 toll like receptor 6 gene PW:0000814 Toll-like receptor signaling pathway ISO RGD:1344850 W RGD:9068941 20211008 RGD PMID:21235323|REF_RGD_ID:5685014 18494543 RSPO1 R-spondin 1 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1603515 W RGD:9068941 20211008 RGD PMID:23151663|REF_RGD_ID:7365105 18494570 MAPKAPK3 MAPK activated protein kinase 3 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1312732 W RGD:9068941 20211008 RGD PMID:16421520|REF_RGD_ID:2315047 18494745 NHERF1 NHERF family PDZ scaffold protein 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1342625 W RGD:9068941 20211008 PID PID:200149 18494745 NHERF1 NHERF family PDZ scaffold protein 1 gene PW:0000565 eicosanoid signaling pathway ISO RGD:1342625 W RGD:9068941 20211008 PID PID:200082 18494745 NHERF1 NHERF family PDZ scaffold protein 1 gene PW:0001135 parathyroid hormone signaling pathway ISO RGD:1342625 W RGD:9068941 20211008 RGD PMID:21777186|REF_RGD_ID:7207465 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0000218 heme biosynthetic pathway ISO RGD:68392 W RGD:9068941 20211008 RGD PMID:16125296|REF_RGD_ID:1601233 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0000218 heme biosynthetic pathway ISO RGD:68572 W RGD:9068941 20211008 RGD PMID:16839620|PMID:26785297|REF_RGD_ID:11554188|REF_RGD_ID:4144542 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0000958 forkhead class A signaling pathway ISO RGD:68572 W RGD:9068941 20211008 PID PID:200087 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0001670 sarcosinemia pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00244 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0001785 variegate porphyria pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00346 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0001981 hereditary coproporphyria pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00342 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0002017 acute intermittent porphyria pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00344 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00179 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0002216 erythropoietic porphyria pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00345 18494940 ALAS1 5'-aminolevulinate synthase 1 gene PW:0002285 porphyrin metabolic pathway ISO RGD:68572 W RGD:9068941 20211008 SMPDB SMP:00024 18494962 RPS25 ribosomal protein S25 gene PW:0000101 translation pathway ISO RGD:1353637 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18494962 RPS25 ribosomal protein S25 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1353637 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18494972 BMPR2 bone morphogenetic protein receptor type 2 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:71082 W RGD:9068941 20211008 RGD PMID:16361357|REF_RGD_ID:1580077 18494972 BMPR2 bone morphogenetic protein receptor type 2 gene PW:0000330 Bone morphogenetic proteins signaling pathway ISO RGD:735373 W RGD:9068941 20211008 PID PID:200144 18495585 TP53 tumor protein p53 gene PW:0000609 prostate cancer pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:23759327|REF_RGD_ID:8693397 18495585 TP53 tumor protein p53 gene PW:0000611 endometrial cancer pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:19078924|REF_RGD_ID:4143515 18495585 TP53 tumor protein p53 gene PW:0000626 pancreatic cancer pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:18772397|REF_RGD_ID:5490966 18495585 TP53 tumor protein p53 gene PW:0000705 non-small cell lung carcinoma pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:20951313|REF_RGD_ID:5133242 18495585 TP53 tumor protein p53 gene PW:0000718 p53 signaling pathway ISO RGD:70502 W RGD:9068941 20211008 PID PID:200206 18495585 TP53 tumor protein p53 gene PW:0000718 p53 signaling pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:16601750|PMID:19450511|REF_RGD_ID:2316155|REF_RGD_ID:2316156 18495585 TP53 tumor protein p53 gene PW:0000720 altered p53 signaling pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:18772397|PMID:19078924|PMID:19165225|PMID:20951313|PMID:22713868|PMID:23263379|PMID:23759327|REF_RGD_ID:2316186|REF_RGD_ID:4143515|REF_RGD_ID:5133242|REF_RGD_ID:5490966|REF_RGD_ID:8663430|REF_RGD_ID:8663431|REF_RGD_ID:8693397 18495585 TP53 tumor protein p53 gene PW:0001437 titanium dioxide nanoparticle response pathway ISO RGD:70502 W RGD:9068941 20211008 RGD PMID:22614867|REF_RGD_ID:7248687 18495585 TP53 tumor protein p53 gene PW:0001678 vinblastine pharmacodynamics pathway ISO RGD:70502 W RGD:9068941 20211008 SMPDB SMP:00436 18495585 TP53 tumor protein p53 gene PW:0001680 vincristine pharmacodynamics pathway ISO RGD:70502 W RGD:9068941 20211008 SMPDB SMP:00437 18495585 TP53 tumor protein p53 gene PW:0001682 vindesine pharmacodynamics pathway ISO RGD:70502 W RGD:9068941 20211008 SMPDB SMP:00438 18495585 TP53 tumor protein p53 gene PW:0001684 vinorelbine pharmacodynamics pathway ISO RGD:70502 W RGD:9068941 20211008 SMPDB SMP:00439 18495603 DKK4 dickkopf WNT signaling pathway inhibitor 4 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1318528 W RGD:9068941 20211008 RGD PMID:17143291|REF_RGD_ID:2301921 18495603 DKK4 dickkopf WNT signaling pathway inhibitor 4 gene PW:0000201 Wnt signaling, canonical pathway ISO RGD:1318529 W RGD:9068941 20211008 RGD PMID:17143291|REF_RGD_ID:2301921 18495837 IL4I1 interleukin 4 induced 1 gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00033 18495837 IL4I1 interleukin 4 induced 1 gene PW:0001417 Canavan disease pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00175 18495837 IL4I1 interleukin 4 induced 1 gene PW:0001609 tyrosinemia type II pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00369 18495837 IL4I1 interleukin 4 induced 1 gene PW:0001610 tyrosinemia type III pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00370 18495837 IL4I1 interleukin 4 induced 1 gene PW:0001805 phenylketonuria pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00206 18495837 IL4I1 interleukin 4 induced 1 gene PW:0001841 homocystinuria pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00177 18495837 IL4I1 interleukin 4 induced 1 gene PW:0001868 hypermethioninemia pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00221 18495837 IL4I1 interleukin 4 induced 1 gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00222 18495837 IL4I1 interleukin 4 induced 1 gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00340 18495837 IL4I1 interleukin 4 induced 1 gene PW:0002471 hypermethioninemia pathway ISO RGD:1312498 W RGD:9068941 20211008 SMPDB SMP:00341 18495862 FNIP1 folliculin interacting protein 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1606476 W RGD:9068941 20211008 RGD PMID:27076075|REF_RGD_ID:11535042 18495977 COPS5 COP9 signalosome subunit 5 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:1321125 W RGD:9068941 20211008 PID PID:200202 18496054 MTFP1 mitochondrial fission process 1 gene PW:0001998 mitochondria fission pathway ISO RGD:1604816 W RGD:9068941 20211008 RGD PMID:21683788|PMID:24442478|REF_RGD_ID:10402101|REF_RGD_ID:10402102 18496174 PGM2 phosphoglucomutase 2 gene PW:0000532 glycogen biosynthetic pathway ISO RGD:1314459 W RGD:9068941 20211008 RGD PMID:9549096|REF_RGD_ID:2304188 18496174 PGM2 phosphoglucomutase 2 gene PW:0000534 glycogen degradation pathway ISO RGD:1314459 W RGD:9068941 20211008 RGD PMID:9549096|REF_RGD_ID:2304188 18496202 CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 gene PW:0000180 mTOR signaling pathway ISO RGD:2306475 W RGD:9068941 20211008 RGD PMID:27015302|REF_RGD_ID:11535047 18496338 EGR1 early growth response 1 gene PW:0000060 long term potentiation ISO RGD:2544 W RGD:9068941 20211008 RGD PMID:16930406|REF_RGD_ID:1626499 18496427 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 gene PW:0001139 calcium transport pathway ISO RGD:732576 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18496427 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 gene PW:0001140 calcium/calcium-mediated signaling pathway ISO RGD:732576 W RGD:9068941 20211008 RGD PMID:21746798|REF_RGD_ID:7204688 18496427 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 gene PW:0001185 calcium/calmodulin dependent kinase 2 signaling pathway ISO RGD:732576 W RGD:9068941 20211008 RGD PMID:23091085|REF_RGD_ID:7240708 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:736023 W RGD:9068941 20211008 PID PID:200149 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:628847 W RGD:9068941 20211008 RGD PMID:10051439|PMID:17064355|REF_RGD_ID:2298561|REF_RGD_ID:2298577 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:736023 W RGD:9068941 20211008 RGD PMID:17306896|REF_RGD_ID:2293875 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:736023 W RGD:9068941 20211008 PID PID:200020 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000658 glypican signaling pathway ISO RGD:736023 W RGD:9068941 20211008 PID PID:200225 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000681 FasL mediated signaling pathway ISO RGD:736023 W RGD:9068941 20211008 PID PID:200080 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000718 p53 signaling pathway ISO RGD:736023 W RGD:9068941 20211008 PID PID:200206 18496546 MAPK9 mitogen-activated protein kinase 9 gene PW:0000907 interleukin-2 signaling pathway ISO RGD:736023 W RGD:9068941 20211008 PID PID:200098 18496771 PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3 gene PW:0000542 adenosine monophosphate-activated protein kinase (AMPK) signaling pathway ISO RGD:1318621 W RGD:9068941 20211008 RGD PMID:12829246|PMID:15509864|REF_RGD_ID:1600678|REF_RGD_ID:1600679 18496818 SERPINA10 serpin family A member 10 gene PW:0000474 coagulation cascade pathway ISO RGD:1353693 W RGD:9068941 20211008 RGD PMID:23690629|REF_RGD_ID:11352284 18497066 NRP2 neuropilin 2 gene PW:0000243 vascular endothelial growth factor signaling pathway ISO RGD:732191 W RGD:9068941 20211008 PID PID:200109 18497239 APH1A aph-1 homolog A, gamma-secretase subunit gene PW:0000204 Notch signaling pathway ISO RGD:1349695 W RGD:9068941 20211008 PID PID:200015 18497239 APH1A aph-1 homolog A, gamma-secretase subunit gene PW:0000204 Notch signaling pathway ISO RGD:1349695 W RGD:9068941 20211008 RGD PMID:17761886|REF_RGD_ID:2302204 18497239 APH1A aph-1 homolog A, gamma-secretase subunit gene PW:0000659 syndecan signaling pathway ISO RGD:1349695 W RGD:9068941 20211008 PID PID:200198 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1346951 W RGD:9068941 20211008 RGD PMID:23073625|REF_RGD_ID:7242425 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00033 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000048 methionine cycle/metabolic pathway ISO RGD:621496 W RGD:9068941 20211008 RGD PMID:15845641|REF_RGD_ID:1359026 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000212 choline metabolic pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00123 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:1346951 W RGD:9068941 20211008 RGD PMID:20346934|PMID:20814827|REF_RGD_ID:7242426|REF_RGD_ID:7242428 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00123 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0000401 remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent ISO RGD:621496 W RGD:9068941 20211008 RGD PMID:15845641|REF_RGD_ID:1359026 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0001670 sarcosinemia pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00244 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0001808 nonketotic hyperglycinemia pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00223|SMP:00485 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0001841 homocystinuria pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00177 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0001868 hypermethioninemia pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00221 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0002209 dimethylglycine dehydrogenase deficiency pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00242|SMP:00484 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0002210 dihydropyrimidine dehydrogenase deficiency pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00179 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0002299 glycine N-methyltransferase deficiency pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00222 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0002343 methylenetetrahydrofolate reductase deficiency pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00340 18497330 BHMT betaine--homocysteine S-methyltransferase gene PW:0002471 hypermethioninemia pathway ISO RGD:1346951 W RGD:9068941 20211008 SMPDB SMP:00341 18497391 MED8 mediator complex subunit 8 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1313646 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18497402 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene PW:0000040 steroid hormone biosynthetic pathway ISO RGD:737091 W RGD:9068941 20211008 SMPDB SMP:00130 18497402 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene PW:0001479 lipoid congenital adrenal hyperplasia pathway ISO RGD:737091 W RGD:9068941 20211008 SMPDB SMP:00371 18497402 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene PW:0002166 17-alpha-hydroxylase deficiency pathway ISO RGD:737091 W RGD:9068941 20211008 SMPDB SMP:00372 18497402 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene PW:0002167 21-alpha-hydroxylase deficiency pathway ISO RGD:737091 W RGD:9068941 20211008 SMPDB SMP:00373 18497402 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene PW:0002168 11-beta-hydroxylase deficiency pathway ISO RGD:737091 W RGD:9068941 20211008 SMPDB SMP:00575 18497402 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene PW:0002466 apparent mineralocorticoid excess syndrome pathway ISO RGD:737091 W RGD:9068941 20211008 SMPDB SMP:00717 18497465 EBI3 Epstein-Barr virus induced 3 gene PW:0000916 interleukin-27 signaling pathway ISO RGD:1353395 W RGD:9068941 20211008 PID PID:200028 18497486 BCAR1 BCAR1 scaffold protein, Cas family member gene PW:0000238 insulin-like growth factor signaling pathway ISO RGD:734116 W RGD:9068941 20211008 PID PID:200100 18497486 BCAR1 BCAR1 scaffold protein, Cas family member gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:734116 W RGD:9068941 20211008 PID PID:200149 18497486 BCAR1 BCAR1 scaffold protein, Cas family member gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:734116 W RGD:9068941 20211008 PID PID:200216 18497486 BCAR1 BCAR1 scaffold protein, Cas family member gene PW:0000506 endothelin signaling pathway ISO RGD:734116 W RGD:9068941 20211008 PID PID:200005 18497526 TIMM50 translocase of inner mitochondrial membrane 50 gene PW:0002137 presequence pathway of mitochondrial protein import ISO RGD:1606193 W RGD:9068941 20211008 RGD PMID:25542066|PMID:25633533|REF_RGD_ID:10412658|REF_RGD_ID:10412659 18497637 MED7 mediator complex subunit 7 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1321085 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18497811 RPS10 ribosomal protein S10 gene PW:0000101 translation pathway ISO RGD:733640 W RGD:9068941 20211008 RGD PMID:23636399|REF_RGD_ID:10002762 18497811 RPS10 ribosomal protein S10 gene PW:0001066 ribosome biogenesis pathway ISO RGD:733640 W RGD:9068941 20211008 RGD PMID:20819938|PMID:23636399|REF_RGD_ID:10002730|REF_RGD_ID:10002762 18497868 CHD7 chromodomain helicase DNA binding protein 7 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1323630 W RGD:9068941 20211008 PID PID:200020 18498077 CPB2 carboxypeptidase B2 gene PW:0000481 fibrinolysis pathway ISO RGD:731734 W RGD:9068941 20211008 RGD PMID:26149056|REF_RGD_ID:11352249 18498194 CHD5 chromodomain helicase DNA binding protein 5 gene PW:0001409 CHD family mediated chromatin remodeling pathway ISO RGD:1317694 W RGD:9068941 20211008 RGD PMID:24880148|REF_RGD_ID:9585661 18498263 CBX6 chromobox 6 gene PW:0001338 histone modification pathway ISO RGD:1316437 W RGD:9068941 20211008 RGD PMID:23473600|PMID:25065329|REF_RGD_ID:9479058|REF_RGD_ID:9479060 18498375 NPM1 nucleophosmin 1 gene PW:0000360 hypoxia inducible factor pathway ISO RGD:735682 W RGD:9068941 20211008 PID PID:200202 18498455 RAC1 Rac family small GTPase 1 gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 RGD PMID:24613967|REF_RGD_ID:10053654 18498455 RAC1 Rac family small GTPase 1 gene PW:0000105 Rho/Rac/Cdc42 mediated signaling pathway ISO RGD:619755 W RGD:9068941 20211008 RGD PMID:9487126|REF_RGD_ID:2293350 18498455 RAC1 Rac family small GTPase 1 gene PW:0000180 mTOR signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200096 18498455 RAC1 Rac family small GTPase 1 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200018 18498455 RAC1 Rac family small GTPase 1 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 RGD PMID:17481747|REF_RGD_ID:2293891 18498455 RAC1 Rac family small GTPase 1 gene PW:0000200 Wnt signaling, the planar cell polarity pathway ISO RGD:1553531 W RGD:9068941 20211008 RGD PMID:15608632|REF_RGD_ID:1581694 18498455 RAC1 Rac family small GTPase 1 gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200149 18498455 RAC1 Rac family small GTPase 1 gene PW:0000313 c-Jun N-terminal kinases MAPK signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 RGD PMID:8910292|PMID:9305638|REF_RGD_ID:2293876|REF_RGD_ID:2293879 18498455 RAC1 Rac family small GTPase 1 gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200052|PID:200204|PID:200216 18498455 RAC1 Rac family small GTPase 1 gene PW:0000387 Arf family mediated signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200195 18498455 RAC1 Rac family small GTPase 1 gene PW:0000506 endothelin signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200005 18498455 RAC1 Rac family small GTPase 1 gene PW:0000516 interleukin-6 signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200146 18498455 RAC1 Rac family small GTPase 1 gene PW:0000565 eicosanoid signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200082 18498455 RAC1 Rac family small GTPase 1 gene PW:0000597 Wnt signaling, non-canonical pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200020 18498455 RAC1 Rac family small GTPase 1 gene PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway ISO RGD:1605432 W RGD:9068941 20211008 RGD PMID:24613967|REF_RGD_ID:10053654 18498455 RAC1 Rac family small GTPase 1 gene PW:0000659 syndecan signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200134 18498455 RAC1 Rac family small GTPase 1 gene PW:0000960 sphingosine 1-phosphate signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200046|PID:200085|PID:200211 18498455 RAC1 Rac family small GTPase 1 gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200116 18498455 RAC1 Rac family small GTPase 1 gene PW:0000992 E-cadherin signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200124|PID:200147 18498455 RAC1 Rac family small GTPase 1 gene PW:0000993 N-cadherin signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 PID PID:200209 18498455 RAC1 Rac family small GTPase 1 gene PW:0001151 Fc epsilon receptor mediated signaling pathway ISO RGD:1605432 W RGD:9068941 20211008 SMPDB SMP:00358 18498455 RAC1 Rac family small GTPase 1 gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:1605432 W RGD:9068941 20211008 SMPDB SMP:00609 18498455 RAC1 Rac family small GTPase 1 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:1605432 W RGD:9068941 20211008 SMPDB SMP:00428 18498455 RAC1 Rac family small GTPase 1 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:1605432 W RGD:9068941 20211008 SMPDB SMP:00427 18498455 RAC1 Rac family small GTPase 1 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:1605432 W RGD:9068941 20211008 SMPDB SMP:00430 18498506 CHRNA10 cholinergic receptor nicotinic alpha 10 subunit gene PW:0000842 acetylcholine signaling pathway via nicotinic acetylcholine receptor ISO RGD:735581 W RGD:9068941 20211008 RGD PMID:19126755|REF_RGD_ID:8549510 18498519 ISCU iron-sulfur cluster assembly enzyme gene PW:0002635 mitochondrial iron-sulfur cluster protein biogenesis pathway ISO RGD:1607067 W RGD:9068941 20211008 RGD PMID:25245479|REF_RGD_ID:11554190 18498531 NME3 NME/NM23 nucleoside diphosphate kinase 3 gene PW:0000862 de novo pyrimidine biosynthetic pathway ISO RGD:733554 W RGD:9068941 20211008 RGD PMID:11768308|REF_RGD_ID:5134680 18498687 EIF3G eukaryotic translation initiation factor 3 subunit G gene PW:0000580 translation initiation pathway ISO RGD:1316234 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18498954 LOX lysyl oxidase gene PW:0000021 hypertension pathway ISO RGD:3015 W RGD:9068941 20211008 RGD PMID:24127|REF_RGD_ID:1581899 18499005 PHYH phytanoyl-CoA 2-hydroxylase gene PW:0001705 Refsum disease pathway ISO RGD:731796 W RGD:9068941 20211008 SMPDB SMP:00451 18499005 PHYH phytanoyl-CoA 2-hydroxylase gene PW:0002564 phytanic acid degradation pathway ISO RGD:731796 W RGD:9068941 20211008 SMPDB SMP:00450 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00075 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00096 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00086 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001524 paracetamol drug pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00710 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00083 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001665 antipyrine drug pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00692 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00116 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00704 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00706 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00094 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00077 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00120 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00114 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00106 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00109 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00098 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00085 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00084 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00289 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00093 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00696 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00104 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00104 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00700 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00709 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00708 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00353 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00705 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00697 18499034 CYP4F8 cytochrome P450 family 4 subfamily F member 8 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:1353889 W RGD:9068941 20211008 SMPDB SMP:00698 18499073 MACROD2 mono-ADP ribosylhydrolase 2 gene PW:0002582 ADP-ribosylation pathway, mono and poly-ribosylation ISO RGD:1347920 W RGD:9068941 20211008 RGD PMID:26091342|REF_RGD_ID:11100038 18499275 FOLR1 folate receptor alpha gene PW:0001207 folate cycle metabolic pathway ISO RGD:1346305 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18499275 FOLR1 folate receptor alpha gene PW:0001208 altered folate cycle metabolic pathway ISO RGD:1346305 W RGD:9068941 20211008 RGD PMID:22108709|REF_RGD_ID:7242557 18499396 SNRPA1 small nuclear ribonucleoprotein polypeptide A' gene PW:0001073 spliceosome pathway ISO RGD:1321959 W RGD:9068941 20211008 RGD PMID:17537823|REF_RGD_ID:9686091 18499474 HSPA8 heat shock protein family A (Hsp70) member 8 gene PW:0000564 androgen signaling pathway ISO RGD:736219 W RGD:9068941 20211008 RGD PMID:16356826|REF_RGD_ID:2326084 18499474 HSPA8 heat shock protein family A (Hsp70) member 8 gene PW:0001073 spliceosome pathway ISO RGD:736219 W RGD:9068941 20211008 RGD PMID:23742842|REF_RGD_ID:9686094 18499474 HSPA8 heat shock protein family A (Hsp70) member 8 gene PW:0002401 chaperone mediated autophagy pathway ISO RGD:736219 W RGD:9068941 20211008 RGD PMID:24281265|PMID:25724482|REF_RGD_ID:10755322|REF_RGD_ID:10755685 18499474 HSPA8 heat shock protein family A (Hsp70) member 8 gene PW:0002432 clathrin-dependent synaptic vesicle endocytosis ISO RGD:736219 W RGD:9068941 20211008 RGD PMID:22763746|REF_RGD_ID:10450547 18499496 ITK IL2 inducible T cell kinase gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:1323169 W RGD:9068941 20211008 PID PID:200116 18499684 CISH cytokine inducible SH2 containing protein gene PW:0000907 interleukin-2 signaling pathway ISO RGD:735426 W RGD:9068941 20211008 PID PID:200098 18499684 CISH cytokine inducible SH2 containing protein gene PW:0000968 interleukin-3 signaling pathway ISO RGD:735426 W RGD:9068941 20211008 PID PID:200145 18499684 CISH cytokine inducible SH2 containing protein gene PW:0000969 interleukin-5 signaling pathway ISO RGD:735426 W RGD:9068941 20211008 PID PID:200107 18499684 CISH cytokine inducible SH2 containing protein gene PW:0000970 granulocyte-macrophage colony-stimulating factor signaling pathway ISO RGD:735426 W RGD:9068941 20211008 PID PID:200019 18499833 IL10RB interleukin 10 receptor subunit beta gene PW:0000515 Interleukin-10 signaling pathway ISO RGD:1345772 W RGD:9068941 20211008 RGD PMID:21115385|REF_RGD_ID:5688379 18500010 RNPS1 RNA binding protein with serine rich domain 1 gene PW:0001073 spliceosome pathway ISO RGD:1316766 W RGD:9068941 20211008 RGD PMID:15145352|REF_RGD_ID:9686404 18500059 PARD6G par-6 family cell polarity regulator gamma gene PW:0000840 protein kinase C (PKC) signaling pathway ISO RGD:1312794 W RGD:9068941 20211008 RGD PMID:16525119|REF_RGD_ID:5132275 18500246 ADCY3 adenylate cyclase 3 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:732499 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18500246 ADCY3 adenylate cyclase 3 gene PW:0000227 G protein mediated signaling pathway via Galphas family ISO RGD:732500 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18500246 ADCY3 adenylate cyclase 3 gene PW:0000506 endothelin signaling pathway ISO RGD:732499 W RGD:9068941 20211008 PID PID:200005 18500246 ADCY3 adenylate cyclase 3 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:732499 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18500246 ADCY3 adenylate cyclase 3 gene PW:0000543 protein kinase A (PKA) signaling pathway ISO RGD:732500 W RGD:9068941 20211008 RGD PMID:18948702|REF_RGD_ID:2312469 18500530 EIF2B1 eukaryotic translation initiation factor 2B subunit alpha gene PW:0000580 translation initiation pathway ISO RGD:733321 W RGD:9068941 20211008 RGD PMID:22815232|REF_RGD_ID:10044017 18500713 KDM6A lysine demethylase 6A gene PW:0001017 renal cell carcinoma pathway ISO RGD:1354488 W RGD:9068941 20211008 RGD PMID:21654818|PMID:22035299|REF_RGD_ID:6907133|REF_RGD_ID:6907137 18500713 KDM6A lysine demethylase 6A gene PW:0001338 histone modification pathway ISO RGD:1354488 W RGD:9068941 20211008 RGD PMID:22663077|PMID:23200123|REF_RGD_ID:7242632|REF_RGD_ID:9479053 18500804 CDK8 cyclin dependent kinase 8 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1348539 W RGD:9068941 20211008 RGD PMID:24088064|REF_RGD_ID:9681732 18500804 CDK8 cyclin dependent kinase 8 gene PW:0000127 RNA polymerase II transcription pathway ISO RGD:1348539 W RGD:9068941 20211008 RGD pol II carboxyl-terminal domain (CTD) PMID:22622228|PMID:23837720|REF_RGD_ID:9681737|REF_RGD_ID:9681738 18500831 KMT5B lysine methyltransferase 5B gene PW:0001338 histone modification pathway ISO RGD:1348608 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18500889 ITGA8 integrin subunit alpha 8 gene PW:0000286 integrin mediated signaling pathway ISO RGD:736147 W RGD:9068941 20211008 RGD PMID:17543136|REF_RGD_ID:5135538 18500889 ITGA8 integrin subunit alpha 8 gene PW:0000286 integrin mediated signaling pathway ISO RGD:736148 W RGD:9068941 20211008 RGD PMID:9054500|REF_RGD_ID:40903006 18500889 ITGA8 integrin subunit alpha 8 gene PW:0000295 altered integrin mediated signaling pathway ISO RGD:736148 W RGD:9068941 20211008 RGD PMID:9054500|REF_RGD_ID:40903006 18500889 ITGA8 integrin subunit alpha 8 gene PW:0000302 glomerulonephritis pathway ISO RGD:621634 W RGD:9068941 20211008 RGD PMID:10504498|REF_RGD_ID:633055 18501088 SNRPE small nuclear ribonucleoprotein polypeptide E gene PW:0001073 spliceosome pathway ISO RGD:1313167 W RGD:9068941 20211008 RGD PMID:17537823|PMID:19239890|REF_RGD_ID:9686089|REF_RGD_ID:9686091 18501240 SNX5 sorting nexin 5 gene PW:0002430 retromer-mediated pathway ISO RGD:1320945 W RGD:9068941 20211008 RGD PMID:25619244|REF_RGD_ID:10450542 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0000034 electron transport chain pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00355 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0000641 gluconeogenesis pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00128 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0001628 triosephosphate isomerase deficiency pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00563 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0001992 glycogen storage disease type Ia pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00374|SMP:00581 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0001993 glycogen storage disease type Ib pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00573 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0002100 fructose-1,6-bisphosphatase deficiency pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00562 18501348 SLC37A4 solute carrier family 37 member 4 gene PW:0002617 phosphoenolpyruvate carboxykinase deficiency pathway ISO RGD:1351082 W RGD:9068941 20211008 SMPDB SMP:00560 18501593 CD8B CD8 subunit beta gene PW:0000914 interleukin-12 signaling pathway ISO RGD:736307 W RGD:9068941 20211008 PID PID:200045 18501889 PGM2L1 phosphoglucomutase 2 like 1 gene PW:0000151 starch and sucrose metabolic pathway ISO RGD:1316099 W RGD:9068941 20211008 SMPDB SMP:00058 18501889 PGM2L1 phosphoglucomutase 2 like 1 gene PW:0001648 congenital sucrase-isomaltase deficiency pathway ISO RGD:1316099 W RGD:9068941 20211008 SMPDB SMP:00557 18501889 PGM2L1 phosphoglucomutase 2 like 1 gene PW:0001994 glycogen storage disease type III pathway ISO RGD:1316099 W RGD:9068941 20211008 SMPDB SMP:00553 18501889 PGM2L1 phosphoglucomutase 2 like 1 gene PW:0001995 glycogen storage disease type IV pathway ISO RGD:1316099 W RGD:9068941 20211008 SMPDB SMP:00554 18501889 PGM2L1 phosphoglucomutase 2 like 1 gene PW:0001996 glycogen storage disease type VI pathway ISO RGD:1316099 W RGD:9068941 20211008 SMPDB SMP:00555 18502176 VPS26A VPS26, retromer complex component A gene PW:0002430 retromer-mediated pathway ISO RGD:1343417 W RGD:9068941 20211008 RGD PMID:25619244|REF_RGD_ID:10450542 18502248 CCNT1 cyclin T1 gene PW:0001331 RNA polymerase II transcription elongation pathway ISO RGD:1322457 W RGD:9068941 20211008 RGD PMID:24050178|REF_RGD_ID:9681735 18502444 FASN fatty acid synthase gene PW:0000029 fatty acid biosynthetic pathway ISO RGD:1347691 W RGD:9068941 20211008 RGD PMID:17882277|PMID:19181734|REF_RGD_ID:2317204|REF_RGD_ID:2317309 18502444 FASN fatty acid synthase gene PW:0000029 fatty acid biosynthetic pathway ISO RGD:1347691 W RGD:9068941 20211008 SMPDB SMP:00456 18502444 FASN fatty acid synthase gene PW:0000029 fatty acid biosynthetic pathway ISO RGD:620665 W RGD:9068941 20211008 RGD PMID:15715522|REF_RGD_ID:2317317 18502573 SNPH syntaphilin gene PW:0002061 mitochondria transport pathway ISO RGD:1314155 W RGD:9068941 20211008 RGD PMID:25612908|REF_RGD_ID:10402141 18502759 MRAP2 melanocortin 2 receptor accessory protein 2 gene PW:0000365 melanocortin system pathway ISO RGD:1320449 W RGD:9068941 20211008 RGD PMID:20654690|REF_RGD_ID:5144214 18502773 RBM8A RNA binding motif protein 8A gene PW:0001073 spliceosome pathway ISO RGD:1320809 W RGD:9068941 20211008 RGD PMID:15145352|REF_RGD_ID:9686404 18502792 CEBPA CCAAT enhancer binding protein alpha gene PW:0000958 forkhead class A signaling pathway ISO RGD:69121 W RGD:9068941 20211008 PID PID:200087 18502870 CHKA choline kinase alpha gene PW:0000354 glycerophospholipid metabolic pathway ISO RGD:1604072 W RGD:9068941 20211008 SMPDB SMP:00025 18502931 LYRM4 LYR motif containing 4 gene PW:0002635 mitochondrial iron-sulfur cluster protein biogenesis pathway ISO RGD:1345825 W RGD:9068941 20211008 RGD PMID:25245479|REF_RGD_ID:11554190 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0000031 purine metabolic pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00050 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:70879 W RGD:9068941 20211008 RGD PMID:9332377|REF_RGD_ID:70804 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0000189 folate mediated one-carbon metabolic pathway ISO RGD:731594 W RGD:9068941 20211008 RGD PMID:22332074|REF_RGD_ID:7242561 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0000867 de novo purine biosynthetic pathway ISO RGD:70879 W RGD:9068941 20211008 RGD PMID:9332377|REF_RGD_ID:70804 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0000867 de novo purine biosynthetic pathway ISO RGD:731594 W RGD:9068941 20211008 RGD PMID:20005278|REF_RGD_ID:5135488 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001590 xanthinuria pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00220 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001591 xanthinuria type I pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00512 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001592 xanthinuria type II pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00513 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001777 purine nucleoside phosphorylase deficiency pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00210 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001779 adenosine monophosphate deaminase deficiency pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00537 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001817 molybdenum cofactor deficiency pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00203 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001879 Lesch-Nyhan syndrome pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00364 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001938 Kelley-Seegmiller syndrome pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00365 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00428 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00427 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0002276 adenylosuccinate lyase deficiency pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00167 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0002294 AICA-ribosuria pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00168 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00430 18502938 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene PW:0002566 adenine phoshoribosyltransferase deficiency pathway ISO RGD:731594 W RGD:9068941 20211008 SMPDB SMP:00535 18503031 TP53BP1 tumor protein p53 binding protein 1 gene PW:0000203 non-homologous end joining pathway of double-strand break repair ISO RGD:1317577 W RGD:9068941 20211008 RGD PMID:24326623|REF_RGD_ID:8661237 18503031 TP53BP1 tumor protein p53 binding protein 1 gene PW:0001338 histone modification pathway ISO RGD:1317577 W RGD:9068941 20211008 RGD PMID:23642229|PMID:24035451|REF_RGD_ID:9479074|REF_RGD_ID:9479148 18503031 TP53BP1 tumor protein p53 binding protein 1 gene PW:0001361 ataxia telangiectasia-mutated (ATM) signaling pathway ISO RGD:1317577 W RGD:9068941 20211008 RGD PMID:24326623|REF_RGD_ID:8661237 18503499 FGR FGR proto-oncogene, Src family tyrosine kinase gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:733253 W RGD:9068941 20211008 PID PID:200149 18503499 FGR FGR proto-oncogene, Src family tyrosine kinase gene PW:0000322 ephrin - ephrin receptor bidirectional signaling axis ISO RGD:733253 W RGD:9068941 20211008 PID PID:200142|PID:200204 18503499 FGR FGR proto-oncogene, Src family tyrosine kinase gene PW:0000565 eicosanoid signaling pathway ISO RGD:733253 W RGD:9068941 20211008 PID PID:200082 18503499 FGR FGR proto-oncogene, Src family tyrosine kinase gene PW:0000658 glypican signaling pathway ISO RGD:733253 W RGD:9068941 20211008 PID PID:200026 18503499 FGR FGR proto-oncogene, Src family tyrosine kinase gene PW:0000963 phosphatidylinositol 3-kinase class I signaling pathway ISO RGD:733253 W RGD:9068941 20211008 PID PID:200116 18503614 HDAC9 histone deacetylase 9 gene PW:0001338 histone modification pathway ISO RGD:1353912 W RGD:9068941 20211008 RGD PMID:21151613|REF_RGD_ID:9104959 18503792 CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 gene PW:0000180 mTOR signaling pathway ISO RGD:2306471 W RGD:9068941 20211008 RGD PMID:27015302|REF_RGD_ID:11535047 18503825 QARS1 glutaminyl-tRNA synthetase 1 gene PW:0000027 glutamic acid/glutamate metabolic pathway ISO RGD:1346181 W RGD:9068941 20211008 SMPDB SMP:00072 18503825 QARS1 glutaminyl-tRNA synthetase 1 gene PW:0001649 succinic semialdehyde dehydrogenase deficiency pathway ISO RGD:1346181 W RGD:9068941 20211008 SMPDB SMP:00243|SMP:00567 18503825 QARS1 glutaminyl-tRNA synthetase 1 gene PW:0001979 homocarnosinosis pathway ISO RGD:1346181 W RGD:9068941 20211008 SMPDB SMP:00385 18503825 QARS1 glutaminyl-tRNA synthetase 1 gene PW:0002205 2-hydroxyglutaric aciduria pathway ISO RGD:1346181 W RGD:9068941 20211008 SMPDB SMP:00136 18503879 NOL12 nucleolar protein 12 gene PW:0001066 ribosome biogenesis pathway ISO RGD:1601850 W RGD:9068941 20211008 RGD PMID:23439679|PMID:25346433|REF_RGD_ID:9999448|REF_RGD_ID:9999449 18503915 GLO1 glyoxalase I gene PW:0000043 pyruvate metabolic pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00060 18503915 GLO1 glyoxalase I gene PW:0001416 Leigh disease pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00196 18503915 GLO1 glyoxalase I gene PW:0001706 pyruvate kinase deficiency of red cells pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00559 18503915 GLO1 glyoxalase I gene PW:0001752 pyruvate decarboxylase deficiency pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00212 18503915 GLO1 glyoxalase I gene PW:0001753 pyruvate dehydrogenase E1 deficiency pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00334 18503915 GLO1 glyoxalase I gene PW:0001783 primary hyperoxaluria type 2 pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00558 18503915 GLO1 glyoxalase I gene PW:0002615 glyoxalase metabolic pathway ISO RGD:1350387 W RGD:9068941 20211008 SMPDB SMP:00459 18504121 GDI2 GDP dissociation inhibitor 2 gene PW:0000159 Rab family mediated signaling pathway ISO RGD:61802 W RGD:9068941 20211008 RGD PMID:8188702|REF_RGD_ID:61604 18504205 GNPAT glyceronephosphate O-acyltransferase gene PW:0001876 plasmalogen metabolic pathway ISO RGD:733936 W RGD:9068941 20211008 SMPDB SMP:00479 18504205 GNPAT glyceronephosphate O-acyltransferase gene PW:0001877 plasmalogen biosynthetic pathway ISO RGD:733936 W RGD:9068941 20211008 SMPDB SMP:00479 18504310 CNDP1 carnosine dipeptidase 1 gene PW:0000051 histidine metabolic pathway ISO RGD:1344598 W RGD:9068941 20211008 SMPDB SMP:00044 18504310 CNDP1 carnosine dipeptidase 1 gene PW:0000077 beta-alanine metabolic pathway ISO RGD:1344598 W RGD:9068941 20211008 SMPDB SMP:00007 18504310 CNDP1 carnosine dipeptidase 1 gene PW:0001978 histidinemia pathway ISO RGD:1344598 W RGD:9068941 20211008 SMPDB SMP:00191 18504310 CNDP1 carnosine dipeptidase 1 gene PW:0002095 GABA aminotransferase deficiency pathway ISO RGD:1344598 W RGD:9068941 20211008 SMPDB SMP:00351 18504310 CNDP1 carnosine dipeptidase 1 gene PW:0002565 carnosinemia pathway ISO RGD:1344598 W RGD:9068941 20211008 SMPDB SMP:00493 18504653 ZNHIT1 zinc finger HIT-type containing 1 gene PW:0000718 p53 signaling pathway ISO RGD:1318185 W RGD:9068941 20211008 RGD PMID:20679336|REF_RGD_ID:8662965 18504653 ZNHIT1 zinc finger HIT-type containing 1 gene PW:0001408 INO80 family mediated chromatin remodeling pathway ISO RGD:1318185 W RGD:9068941 20211008 RGD PMID:21502417|REF_RGD_ID:9495926 18504686 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene PW:0000039 bile acid biosynthetic pathway ISO RGD:69210 W RGD:9068941 20211008 SMPDB SMP:00035 18504686 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene PW:0001093 bile acid signaling pathway ISO RGD:69210 W RGD:9068941 20211008 RGD PMID:28774887|REF_RGD_ID:15045601 18504686 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene PW:0001415 Zellweger syndrome pathway ISO RGD:69210 W RGD:9068941 20211008 SMPDB SMP:00316 18504686 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene PW:0001475 cerebrotendinous xanthomatosis pathway ISO RGD:69210 W RGD:9068941 20211008 SMPDB SMP:00315 18504686 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene PW:0002302 familial hypercholanemia pathway ISO RGD:69210 W RGD:9068941 20211008 SMPDB SMP:00317 18504686 CYP7A1 cytochrome P450 family 7 subfamily A member 1 gene PW:0002481 congenital bile acid synthesis defect pathway ISO RGD:69210 W RGD:9068941 20211008 SMPDB SMP:00314|SMP:00318 18504780 KDM1A lysine demethylase 1A gene PW:0000204 Notch signaling pathway ISO RGD:1346422 W RGD:9068941 20211008 PID PID:200015 18504780 KDM1A lysine demethylase 1A gene PW:0001338 histone modification pathway ISO RGD:1346422 W RGD:9068941 20211008 RGD PMID:23200123|REF_RGD_ID:7242632 18504869 LDHA lactate dehydrogenase A gene PW:0000360 hypoxia inducible factor pathway ISO RGD:736025 W RGD:9068941 20211008 PID PID:200202 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0000381 multidrug resistance-associated protein mediated transport pathway ISO RGD:70913 W RGD:9068941 20211008 RGD PMID:10893247|REF_RGD_ID:632215 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0000381 multidrug resistance-associated protein mediated transport pathway ISO RGD:734363 W RGD:9068941 20211008 RGD PMID:12433976|REF_RGD_ID:1358123 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0001525 paracetamol pharmacokinetics pathway ISO RGD:734363 W RGD:9068941 20211008 SMPDB SMP:00640 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0001943 mercaptopurine pharmacokinetics pathway ISO RGD:734363 W RGD:9068941 20211008 SMPDB SMP:00609 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0001944 mercaptopurine pharmacodynamics pathway ISO RGD:734363 W RGD:9068941 20211008 SMPDB SMP:00428 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0002203 azathioprine pharmacodynamics pathway ISO RGD:734363 W RGD:9068941 20211008 SMPDB SMP:00427 18505009 ABCC5 ATP binding cassette subfamily C member 5 gene PW:0002394 tioguanine pharmacodynamics pathway ISO RGD:734363 W RGD:9068941 20211008 SMPDB SMP:00430 18505123 RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase gene PW:0001573 tRNA maturation pathway ISO RGD:1605075 W RGD:9068941 20211008 RGD PMID:25071838|REF_RGD_ID:9685342 18505250 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 gene PW:0000388 Reelin signaling pathway ISO RGD:733787 W RGD:9068941 20211008 PID PID:200062 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000460 arachidonic acid metabolic pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00075 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000726 repaglinide pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 RGD PMID:17253883|REF_RGD_ID:2316509 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000729 statin pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 RGD PMID:17353665|REF_RGD_ID:2316977 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000730 warfarin pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 RGD PMID:26655108|REF_RGD_ID:11354883 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000763 celecoxib pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00096 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000765 ifosfamide pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00605 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000766 ifosfamide pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00448 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0000838 tamoxifen pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 RGD PMID:12971802|REF_RGD_ID:5129544 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001108 sorafenib pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00648 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001463 losartan pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 RGD PMID:23118328|REF_RGD_ID:7364964 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001469 ibuprofen pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00590 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001470 ibuprofen pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00086 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001524 paracetamol drug pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00710 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001615 acetylsalicylic acid pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00083 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001665 antipyrine drug pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00692 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001696 valdecoxib pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00116 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001750 tolmetin pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00704 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001795 tenoxicam pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00706 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001801 sulindac pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00094 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001867 piroxicam pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00077 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001915 naproxen pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00120 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001924 nabumetone pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00114 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001940 methadone pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00624 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001941 methadone pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00408 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001950 meloxicam pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00106 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001953 mefenamic acid pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00109 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001968 ketorolac pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00098 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0001971 ketoprofen pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00085 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002042 etodolac pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00084 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002081 diflunisal pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00289 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002087 diclofenac pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00093 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002108 cyclophosphamide pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00604 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002109 cyclophosphamide pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00447 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002280 fenoprofen pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00696 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002305 indometacin pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00104 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002315 indometacin pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00104 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002318 caffeine pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00028 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002350 lornoxicam pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00700 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002458 salicylic acid pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00709 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002462 sodium salicylate pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00708 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002464 carbamazepine pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00634 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002477 rosiglitazone pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00653 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002491 leukotriene C4 synthase deficiency pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00353 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002508 mycophenolic acid pharmacokinetics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00652 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002516 tiaprofenic acid pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00705 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002524 flurbiprofen pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00697 18505283 CYP2C8 cytochrome P450 family 2 subfamily C member 8 gene PW:0002530 magnesium salicylate pharmacodynamics pathway ISO RGD:1606589 W RGD:9068941 20211008 SMPDB SMP:00698 18505319 AQP7 aquaporin 7 gene PW:0000419 water transport pathway ISO RGD:2145 W RGD:9068941 20211008 RGD PMID:19096774|REF_RGD_ID:2312795 18505319 AQP7 aquaporin 7 gene PW:0000419 water transport pathway ISO RGD:736375 W RGD:9068941 20211008 RGD PMID:19096774|REF_RGD_ID:2312795 18505319 AQP7 aquaporin 7 gene PW:0000419 water transport pathway ISO RGD:736376 W RGD:9068941 20211008 RGD PMID:19096774|REF_RGD_ID:2312795 18505407 MKNK2 MAPK interacting serine/threonine kinase 2 gene PW:0000102 the extracellular signal-regulated Raf/Mek/Erk signaling pathway ISO RGD:1313930 W RGD:9068941 20211008 RGD PMID:16421520|REF_RGD_ID:2315047 18505407 MKNK2 MAPK interacting serine/threonine kinase 2 gene PW:0000198 p38 MAPK signaling pathway ISO RGD:1313930 W RGD:9068941 20211008 RGD PMID:16421520|REF_RGD_ID:2315047 18505429 JUND JunD proto-oncogene, AP-1 transcription factor subunit gene PW:0000297 platelet-derived growth factor signaling pathway ISO RGD:735346 W RGD:9068941 20211008 PID PID:200149 18505556 EIF3K eukaryotic translation initiation factor 3 subunit K gene PW:0000580 translation initiation pathway ISO RGD:1342979 W RGD:9068941 20211008 RGD PMID:24499181|REF_RGD_ID:10002776 18505711 UPP2 uridine phosphorylase 2 gene PW:0000032 pyrimidine metabolic pathway ISO RGD:1317821 W RGD:9068941 20211008 SMPDB SMP:00046 18505711 UPP2 uridine phosphorylase 2 gene PW:0001603 beta-ureidopropionase deficiency pathway ISO RGD:1317821 W RGD:9068941 20211008 SMPDB SMP:00172 18505711 UPP2 uridine phosphorylase 2 gene PW:0001605 orotic aciduria 1 pathway ISO RGD:1317821 W RGD:9068941 20211008 SMPDB SMP:00219 18505711 UPP2 uridine phosphorylase 2 gene PW:0002211 dihydropyrimidinase deficiency pathway ISO RGD:1317821 W RGD:9068941 20211008 SMPDB SMP:00178 18505711 UPP2 uridine phosphorylase 2 gene PW:0002365 mitochondrial neurogastrointestinal encephalopathy syndrome pathway IS