# RGD-PIPELINE: ftp-file-extracts
# MODULE: annotations-version-1.1.9 (Oct 10, 2019)
# GENERATED-ON: 2025/07/19
# PURPOSE: annotations about active Dog objects extracted from RGD database
# ONTOLOGY: ChEBI: ChEBI Ontology
# CONTACT: rgd.data@mcw.edu
# FORMAT: tab delimited text
# NOTES: multiple values in a single column are separated by '|'
#
#COLUMN INFORMATION:
#
#1 RGD_ID unique RGD_ID of the annotated object
#2 OBJECT_SYMBOL official symbol of the annotated object
#3 OBJECT_NAME official name of the annotated object
#4 OBJECT_TYPE annotated object data type: one of ['gene','qtl','strain']
#5 TERM_ACC_ID ontology term accession id
#6 TERM_NAME ontology term name
#7 QUALIFIER optional qualifier
#8 EVIDENCE evidence
#9 WITH with info
#10 ASPECT aspect
#11 REFERENCES db references (Reference RGDID|PUBMED ID)
#12 CREATED_DATE created date
#13 ASSIGNED_BY assigned by
#14 MESH_OMIM_ID MESH:xxx or OMIM:xxx id corresponding to RDO:xxx id found in TERM_ACC_ID column (RGD/CTD Disease Ontology annotations only)
#15 CURATION_NOTES curation notes provided by RGD curators
#16 ORIGINAL_REFERENCE original reference
RGD_ID OBJECT_SYMBOL OBJECT_NAME OBJECT_TYPE TERM_ACC_ID TERM_NAME QUALIFIER EVIDENCE WITH ASPECT REFERENCES CREATED_DATE ASSIGNED_BY MESH_OMIM_ID CURATION_NOTES ORIGINAL_REFERENCE
12050654 CMTM7 CKLF like MARVEL transmembrane domain containing 7 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CMTM7 mRNA PMID:22747577
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:16170 mercury(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein PMID:15590114
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:16170 mercury(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 ABCC1 protein affects the export of and results in decreased susceptibility to Mercury PMID:15590114
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:16978 leukotriene C4 affects transport EXP E RGD:6480464 20191114 CTD MESH:D017997 ABCC1 protein affects the transport of Leukotriene C4 PMID:12516967
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:25195 mercury atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein PMID:15590114
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:25195 mercury atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 ABCC1 protein affects the export of and results in decreased susceptibility to Mercury PMID:15590114
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:28445 vincristine decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D014750 ABCC1 protein results in decreased susceptibility to Vincristine PMID:12516967
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:31823 mercury dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased expression of ABCC1 mRNA; Mercuric Chloride results in increased expression of ABCC1 protein PMID:15590114
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:31823 mercury dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008627 ABCC1 protein affects the export of and results in decreased susceptibility to Mercuric Chloride PMID:15590114
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:3303 calcein am affects export EXP E RGD:6480464 20191114 CTD MESH:C085925 ABCC1 protein affects the export of calcein AM PMID:12516967
12050846 ABCC1 ATP binding cassette subfamily C member 1 gene CHEBI:4911 etoposide decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D005047 ABCC1 protein results in decreased susceptibility to Etoposide PMID:12516967
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:16170 mercury(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased expression of ABCC2 mRNA; Mercury results in increased expression of ABCC2 protein PMID:15590114
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:16170 mercury(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 ABCC2 protein affects the export of and results in decreased susceptibility to Mercury PMID:15590114
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:16469 17beta-estradiol affects transport EXP E RGD:6480464 20191114 CTD MESH:D004958 ABCC2 protein affects the transport of Estradiol PMID:15507541
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:16978 leukotriene C4 affects transport EXP E RGD:6480464 20191114 CTD MESH:D017997 ABCC2 protein affects the transport of Leukotriene C4 PMID:15507541
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:25195 mercury atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D008628 Mercury results in increased expression of ABCC2 mRNA; Mercury results in increased expression of ABCC2 protein PMID:15590114
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:25195 mercury atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008628 ABCC2 protein affects the export of and results in decreased susceptibility to Mercury PMID:15590114
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:31823 mercury dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased expression of ABCC2 mRNA; Mercuric Chloride results in increased expression of ABCC2 protein PMID:15590114
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:31823 mercury dichloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008627 ABCC2 protein affects the export of and results in decreased susceptibility to Mercuric Chloride PMID:15590114
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:63621 saquinavir affects transport EXP E RGD:6480464 20191114 CTD MESH:D019258 ABCC2 protein affects the transport of Saquinavir PMID:12702717
12050879 ABCC2 ATP binding cassette subfamily C member 2 gene CHEBI:9436 Temocaprilat affects transport EXP E RGD:6480464 20191114 CTD MESH:C069156 ABCC2 protein affects the transport of temocaprilat PMID:15507541
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:16240 hydrogen peroxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein PMID:23816505
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] PMID:23816505
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005978 Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein] PMID:23816505
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:26710 sodium chloride increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased phosphorylation of MAPK9 protein PMID:23816505
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein] PMID:23816505
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein] PMID:23816505
12050914 MAPK9 mitogen-activated protein kinase 9 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein] PMID:23816505
12051364 LOC100686073 metallothionein-1 gene CHEBI:31823 mercury dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased expression of MT1 mRNA PMID:15590114
12051493 GNGT1 G protein subunit gamma transducin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GNGT1 mRNA PMID:38866337
12051759 ATG7 autophagy related 7 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of ATG7 mRNA PMID:27255383
12051818 CA2 carbonic anhydrase 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of CA2 mRNA PMID:22747577
12052074 CGREF1 cell growth regulator with EF-hand domain 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CGREF1 mRNA PMID:38866337
12052103 SCUBE2 signal peptide, CUB domain and EGF like domain containing 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SCUBE2 mRNA PMID:38866337
12052140 PIK3IP1 phosphoinositide-3-kinase interacting protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PIK3IP1 mRNA PMID:38866337
12052222 SERPINE2 serpin family E member 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SERPINE2 mRNA PMID:38866337
12052222 SERPINE2 serpin family E member 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of SERPINE2 mRNA PMID:22747577
12052559 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:17154 nicotinamide increases expression EXP E RGD:6480464 20191114 CTD MESH:D009536 Niacinamide results in increased expression of PPARG protein PMID:22539994
12052559 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:17154 nicotinamide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009536 Resveratrol inhibits the reaction [Niacinamide results in increased expression of PPARG protein] PMID:22539994
12052559 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [Niacinamide results in increased expression of PPARG protein] PMID:22539994
12052559 PPARG peroxisome proliferator activated receptor gamma gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPARG mRNA PMID:38866337
12052585 TJP1 tight junction protein 1 gene CHEBI:15367 all-trans-retinoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased expression of TJP1 mRNA; Tretinoin results in increased expression of TJP1 protein PMID:17035595
12052585 TJP1 tight junction protein 1 gene CHEBI:15367 all-trans-retinoic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014212 CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of TJP1 mRNA] PMID:17035595
12052585 TJP1 tight junction protein 1 gene CHEBI:60579 calcium oxalate decreases expression EXP E RGD:6480464 20210907 CTD MESH:D002129 Calcium Oxalate results in decreased expression of TJP1 protein PMID:34147488|PMID:36349591
12052585 TJP1 tight junction protein 1 gene CHEBI:60579 calcium oxalate multiple interactions EXP E RGD:6480464 20210907 CTD MESH:D002129 Docetaxel inhibits the reaction [Calcium Oxalate results in decreased expression of TJP1 protein]; Phalloidine inhibits the reaction [Calcium Oxalate results in decreased expression of TJP1 protein] PMID:34147488|PMID:36349591
12052585 TJP1 tight junction protein 1 gene CHEBI:8040 phalloidin multiple interactions EXP E RGD:6480464 20210907 CTD MESH:D010590 Phalloidine inhibits the reaction [Calcium Oxalate results in decreased expression of TJP1 protein] PMID:34147488
12052885 OSR1 odd-skipped related transcription factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of OSR1 mRNA PMID:38866337
12053109 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of CYP1A2 mRNA PMID:19952500
12053109 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:8050 phenacetin affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D010615 CYP1A2 protein affects the metabolism of Phenacetin PMID:15801540
12053109 CYP1A2 cytochrome P450 family 1 subfamily A member 2 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of CYP1A2 mRNA PMID:19952500
12053380 AHCY adenosylhomocysteinase gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of AHCY protein PMID:19952500
12053380 AHCY adenosylhomocysteinase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of AHCY protein PMID:19952500
12053393 CD40 CD40 molecule gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CD40 mRNA PMID:38866337
12053585 SAR1A secretion associated Ras related GTPase 1A gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20250715 CTD MESH:C526575 masitinib results in decreased expression of SAR1A mRNA PMID:22747577
12053832 EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of EHHADH mRNA PMID:19952500
12054230 CD36 CD36 molecule (CD36 blood group) gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CD36 mRNA PMID:38866337
12054509 EIF5A2 eukaryotic translation initiation factor 5A2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of EIF5A2 mRNA PMID:22747577
12054531 FAXDC2 fatty acid hydroxylase domain containing 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAXDC2 mRNA PMID:38866337
12054572 INTS6L integrator complex subunit 6 like gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of INTS6L mRNA PMID:38866337
12054772 MIR30D microRNA mir-30d gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR30D PMID:40036580
12054882 CCL8 C-C motif chemokine ligand 8 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CCL8 mRNA PMID:38866337
12056186 PLSCR4 phospholipid scramblase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PLSCR4 mRNA PMID:38866337
12056203 C26H12orf43 chromosome 26 C12orf43 homolog gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of C26H12ORF43 mRNA PMID:38866337
12056219 AHCYL1 adenosylhomocysteinase like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AHCYL1 mRNA PMID:38866337
12056528 SNRK SNF related kinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SNRK mRNA PMID:38866337
12056992 ANKRD66 ankyrin repeat domain 66 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ANKRD66 mRNA PMID:38866337
12057110 NXPH2 neurexophilin 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NXPH2 mRNA PMID:38866337
12057161 MMP2 matrix metallopeptidase 2 gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of MMP2 protein] PMID:18339021
12057161 MMP2 matrix metallopeptidase 2 gene CHEBI:17883 hydrogen chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in increased expression of MMP2 protein PMID:18339021
12057161 MMP2 matrix metallopeptidase 2 gene CHEBI:17883 hydrogen chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006851 Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of MMP2 protein] PMID:18339021
12057288 TFDP2 transcription factor Dp-2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TFDP2 mRNA PMID:38866337
12057731 TSC22D3 TSC22 domain family member 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TSC22D3 mRNA PMID:38866337
12057924 FDFT1 farnesyl-diphosphate farnesyltransferase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FDFT1 mRNA PMID:38866337
12057976 CHN1 chimerin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CHN1 mRNA PMID:38866337
12058236 EMP1 epithelial membrane protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of EMP1 mRNA PMID:38866337
12058309 BCL2L2 BCL2 like 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BCL2L2 mRNA PMID:38866337
12058553 GNG8 G protein subunit gamma 8 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GNG8 mRNA PMID:38866337
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:144353 diethyldithiocarbamic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004050 Ditiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:17578 toluene affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D014050 CYP2E1 protein affects the metabolism of Toluene PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:17578 toluene multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014050 Ditiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]; Fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:17847 p-cresol affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C032538 CYP2E1 protein affects the metabolism of 4-cresol PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:17987 benzyl alcohol affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D019905 CYP2E1 protein affects the metabolism of Benzyl Alcohol PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:28054 o-cresol affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C034047 CYP2E1 protein affects the metabolism of 2-cresol PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of CYP2E1 protein PMID:19952500
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:5141 fomepizole multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C010238 Fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] PMID:8592870
12058559 CYP2E1 cytochrome P450 family 2 subfamily E member 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of CYP2E1 mRNA PMID:19952500
12059381 SPATS2L spermatogenesis associated serine rich 2 like gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SPATS2L mRNA PMID:38866337
12059801 CTSK cathepsin K gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CTSK mRNA PMID:22747577
12060061 HGF hepatocyte growth factor gene CHEBI:28748 doxorubicin decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D004317 HGF protein results in decreased susceptibility to Doxorubicin PMID:15688034
12060417 CPT2 carnitine palmitoyltransferase 2 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of CPT2 mRNA PMID:19952500
12060472 TBX5 T-box transcription factor 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TBX5 mRNA PMID:38866337
12060747 UGT2B31 UDP-glucuronosyltransferase UGT2B31 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20210119 CTD MESH:D010634 Phenobarbital results in increased expression of UGT2B4 protein PMID:19952500
12061268 SMG8 SMG8 nonsense mediated mRNA decay factor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SMG8 mRNA PMID:38866337
12061456 ZKSCAN8 zinc finger with KRAB and SCAN domains 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZKSCAN8 mRNA PMID:38866337
12061939 CAPN1 calpain 1 gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of CAPN1 mRNA PMID:24582689
12061939 CAPN1 calpain 1 gene CHEBI:9241 spironolactone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in decreased expression of CAPN1 protein PMID:20082611
12062225 IL37 interleukin 37 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IL37 mRNA PMID:38866337
12062987 MAL2 mal, T cell differentiation protein 2 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of MAL2 mRNA PMID:27255383
12063241 TSHZ2 teashirt zinc finger homeobox 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TSHZ2 mRNA PMID:38866337
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:16243 quercetin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] PMID:15266218
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28077 rifampicin increases expression EXP E RGD:6480464 20191114 CTD MESH:D012293 Rifampin results in increased expression of ABCB1 mRNA; Rifampin results in increased expression of ABCB1 protein PMID:22620706
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28411 allicin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006452 allicin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] PMID:15266218
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28445 vincristine affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D014750 ABCB1 protein affects the susceptibility to Vincristine PMID:24975508
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28445 vincristine increases export EXP E RGD:6480464 20191114 CTD MESH:D014750 ABCB1 protein results in increased export of Vincristine PMID:28093773
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28445 vincristine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014750 valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine] PMID:24975508
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28499 kaempferol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006552 kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] PMID:15266218
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28748 doxorubicin affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D004317 ABCB1 protein affects the susceptibility to Doxorubicin PMID:24975508
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28748 doxorubicin increases expression EXP E RGD:6480464 20191114 CTD MESH:D004317 Doxorubicin results in increased expression of ABCB1 protein PMID:28093773
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:28748 doxorubicin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004317 valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]; valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin] PMID:15492788|PMID:24975508
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:31516 Doramectin increases response to substance EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form results in increased susceptibility to doramectin; ABCB1 mutant form results in increased susceptibility to doramectin PMID:22834856|PMID:23186803|PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of ALB mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of DAO mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of EBF3 mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GABRQ mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GLRA1 mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of KLK6 mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of MAB21L2 mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC10A4 mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC18A2 mRNA]; ABCB1 gene mutant form affects the reaction [doramectin affects the expression of TTR mRNA] PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:44658 okadaic acid increases transport EXP E RGD:6480464 20191114 CTD MESH:D019319 ABCB1 protein results in increased transport of Okadaic Acid PMID:24374049
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:45409 ritonavir multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019438 allicin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]; hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]; kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]; Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] PMID:15266218
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:4551 digoxin increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form results in increased susceptibility to Digoxin; ABCB1 mutant form results in increased susceptibility to Digoxin PMID:16594604|PMID:23186803|PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 [ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin]; [Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of ALB mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of DAO mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of EBF3 mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GABRQ mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GLRA1 mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of KLK6 mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of MAB21L2 mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC10A4 mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC18A2 mRNA]; ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of TTR mRNA]; MYL9 protein modified form affects the reaction [ABCB1 protein affects the transport of Digoxin analog] PMID:20510202|PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:47519 ketoconazole decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007654 Ketoconazole results in decreased activity of ABCB1 protein PMID:19754906
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:47519 ketoconazole decreases expression EXP E RGD:6480464 20191114 CTD MESH:D007654 Ketoconazole results in decreased expression of ABCB1 mRNA PMID:22620706
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:47519 ketoconazole multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007654 [Ketoconazole results in decreased activity of ABCB1 protein] which results in decreased transport of Technetium Tc 99m Sestamibi PMID:19754906
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:50345 milbemycin increases response to substance EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form results in increased susceptibility to moxidectin; ABCB1 mutant form results in increased susceptibility to moxidectin PMID:23186803|PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of ALB mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of DAO mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of EBF3 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GABRQ mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GLRA1 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of KLK6 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of MAB21L2 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC10A4 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC18A2 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of TTR mRNA] PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:5051 Fexofenadine hydrochloride decreases uptake EXP E RGD:6480464 20191114 CTD MESH:C093230 ABCB1 protein results in decreased uptake of fexofenadine PMID:18299336
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:5831 Hypaconitine increases transport EXP E RGD:6480464 20191114 CTD MESH:C058309 ABCB1 protein results in increased transport of hypaconitine PMID:23200901
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:5835 hypericin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C004965 hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir] PMID:15266218
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6078 ivermectin affects abundance EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 protein affects the abundance of Ivermectin PMID:20595473
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6078 ivermectin increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form results in increased susceptibility to Ivermectin; ABCB1 mutant form results in increased susceptibility to Ivermectin; ABCB1 protein mutant form results in increased susceptibility to Ivermectin PMID:22834856|PMID:22924731|PMID:23186803|PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of ALB mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of DAO mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of EBF3 mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GABRQ mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GLRA1 mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of KLK6 mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of MAB21L2 mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC10A4 mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC18A2 mRNA]; ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of TTR mRNA] PMID:25419811
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6532 loperamide affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D008139 ABCB1 protein affects the susceptibility to Loperamide PMID:25660379
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6532 loperamide increases export EXP E RGD:6480464 20191114 CTD MESH:D008139 ABCB1 protein results in increased export of Loperamide PMID:28093773
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6773 Mesaconitine increases transport EXP E RGD:6480464 20191114 CTD MESH:C019470 ABCB1 protein results in increased transport of mesaconitine PMID:23200901
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:6916 mexiletine increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D008801 ABCB1 mutant form results in increased susceptibility to Mexiletine PMID:16594604
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:77733 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014700 [Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin PMID:20510202
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:78739 emodepside affects response to substance EXP E RGD:6480464 20191114 CTD MESH:C468987 ABCB1 protein affects the susceptibility to emodepside PMID:25660379
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:78761 ML-7 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C070571 [ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin] PMID:20510202
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:8828 rhodamine 123 increases export EXP E RGD:6480464 20191114 CTD MESH:D020112 ABCB1 protein results in increased export of Rhodamine 123 PMID:28093773
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:8985 SDZ PSC 833 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C070272 valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]; valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]; valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin] PMID:15492788|PMID:24975508
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:9423 Technetium tc 99m sestamibi decreases transport EXP E RGD:6480464 20191114 CTD MESH:D017256 ABCB1 gene mutant form results in decreased transport of Technetium Tc 99m Sestamibi PMID:19754906
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:9423 Technetium tc 99m sestamibi multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017256 [Ketoconazole results in decreased activity of ABCB1 protein] which results in decreased transport of Technetium Tc 99m Sestamibi PMID:19754906
12063362 ABCB1 ATP binding cassette subfamily B member 1 gene CHEBI:9948 verapamil multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014700 [Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin PMID:20510202
12063579 LBX2 ladybird homeobox 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of LBX2 mRNA PMID:22747577
12064076 USP39 ubiquitin specific peptidase 39 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of USP39 mRNA PMID:38866337
12064112 OAT ornithine aminotransferase gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of OAT protein PMID:32991862
12064175 SESN1 sestrin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SESN1 mRNA PMID:38866337
12064677 CSF2 colony stimulating factor 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CSF2 mRNA PMID:38866337
12065058 TERF2 telomeric repeat binding factor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TERF2 mRNA PMID:38866337
12066106 PPP3CA protein phosphatase 3 catalytic subunit alpha gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of PPP3CA mRNA PMID:27255383
12066131 EDN2 endothelin 2 gene CHEBI:88212 lead(II) chloride increases secretion EXP E RGD:6480464 20191114 CTD MESH:C029891 lead chloride results in increased secretion of EDN2 protein PMID:15915659
12066705 LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LYVE1 mRNA PMID:38866337
12066915 MFAP1 microfibril associated protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MFAP1 mRNA PMID:38866337
12067005 MED13 mediator complex subunit 13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MED13 mRNA PMID:38866337
12067040 ALDH7A1 aldehyde dehydrogenase 7 family member A1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ALDH7A1 mRNA PMID:38866337
12067061 BSPRY B-box and SPRY domain containing gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BSPRY mRNA PMID:38866337
12067089 SDCBP syndecan binding protein gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SDCBP mRNA PMID:27255383
12067119 SUMF1 sulfatase modifying factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250325 CTD MESH:C006780 bisphenol A results in increased expression of SUMF1 mRNA PMID:38866337
12067598 CP ceruloplasmin gene CHEBI:18248 iron atom increases export EXP E RGD:6480464 20191114 CTD MESH:D007501 CP protein results in increased export of Iron PMID:16806171
12067598 CP ceruloplasmin gene CHEBI:18248 iron atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007501 [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] PMID:16806171
12067598 CP ceruloplasmin gene CHEBI:82664 iron(0) increases export EXP E RGD:6480464 20191114 CTD MESH:D007501 CP protein results in increased export of Iron PMID:16806171
12067598 CP ceruloplasmin gene CHEBI:82664 iron(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007501 [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] PMID:16806171
12067666 TBC1D8 TBC1 domain family member 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TBC1D8 mRNA PMID:38866337
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of HSPA5 protein PMID:32991862
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:18320 1,4-dithiothreitol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004229 Dithiothreitol metabolite results in increased expression of HSPA5 protein PMID:17416481
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:29699 tunicamycin increases expression EXP E RGD:6480464 20191114 CTD MESH:D014415 Tunicamycin results in increased expression of HSPA5 protein PMID:17416481
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:42106 L-1,4-dithiothreitol increases expression EXP E RGD:6480464 20191114 CTD MESH:D004229 Dithiothreitol metabolite results in increased expression of HSPA5 protein PMID:17416481
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of HSPA5 mRNA PMID:24582689
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of HSPA5 protein PMID:19952500
12067945 HSPA5 heat shock protein family A (Hsp70) member 5 gene CHEBI:9516 thapsigargin increases expression EXP E RGD:6480464 20191114 CTD MESH:D019284 Thapsigargin results in increased expression of HSPA5 protein PMID:17416481
12068159 MCUR1 mitochondrial calcium uniporter regulator 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MCUR1 mRNA PMID:38866337
12068176 TMEM97 transmembrane protein 97 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM97 mRNA PMID:38866337
12068283 TMEM69 transmembrane protein 69 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMEM69 mRNA PMID:38866337
12068328 CDKN1C cyclin dependent kinase inhibitor 1C gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CDKN1C mRNA PMID:38866337
12068442 AKAP12 A-kinase anchoring protein 12 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of AKAP12 mRNA PMID:27255383
12068805 MYBPH myosin binding protein H gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MYBPH mRNA PMID:38866337
12069184 PARP2 poly(ADP-ribose) polymerase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PARP2 mRNA PMID:38866337
12070051 PSAT1 phosphoserine aminotransferase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PSAT1 mRNA PMID:38866337
12071080 PIAS1 protein inhibitor of activated STAT 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PIAS1 mRNA PMID:38866337
12071272 SLC25A34 solute carrier family 25 member 34 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC25A34 mRNA PMID:38866337
12071451 MIR26B microRNA mir-26b gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR26B PMID:40036580
12071595 KCND3 potassium voltage-gated channel subfamily D member 3 gene CHEBI:17347 testosterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D013739 Testosterone results in increased expression of KCND3 protein PMID:17054656
12071595 KCND3 potassium voltage-gated channel subfamily D member 3 gene CHEBI:4784 enalapril decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004656 Enalapril results in decreased expression of KCND3 mRNA PMID:19732978
12071640 ADRA1A adrenoceptor alpha 1A gene CHEBI:135929 silodosin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C095285 silodosin binds to and results in decreased activity of ADRA1A protein; silodosin inhibits the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] PMID:19371927
12071640 ADRA1A adrenoceptor alpha 1A gene CHEBI:8093 phenylephrine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010656 Phenylephrine binds to and results in increased activity of ADRA1A protein; silodosin inhibits the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] PMID:19371927
12071790 TRIM54 tripartite motif containing 54 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TRIM54 mRNA PMID:27255383
12071833 TNPO1 transportin 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of TNPO1 mRNA PMID:22747577
12071943 MERTK MER proto-oncogene, tyrosine kinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MERTK mRNA PMID:38866337
12072025 SLC16A12 solute carrier family 16 member 12 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SLC16A12 mRNA PMID:38866337
12072070 MYLK myosin light chain kinase gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 [ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin] PMID:20510202
12072070 MYLK myosin light chain kinase gene CHEBI:78761 ML-7 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C070571 [ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin] PMID:20510202
12072473 NWD1 NACHT and WD repeat domain containing 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NWD1 mRNA PMID:38866337
12072547 CASP3 caspase 3 gene CHEBI:15367 all-trans-retinoic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased activity of CASP3 protein PMID:16953078
12072547 CASP3 caspase 3 gene CHEBI:192461 toosendanin increases cleavage EXP E RGD:6480464 20240604 CTD MESH:C036454 toosendanin results in increased cleavage of CASP3 protein PMID:36809669
12072547 CASP3 caspase 3 gene CHEBI:3441 carvedilol decreases activity EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased activity of CASP3 protein PMID:12875697
12072547 CASP3 caspase 3 gene CHEBI:4629 diosgenin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004144 Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP3 protein] PMID:25446497
12072547 CASP3 caspase 3 gene CHEBI:60579 calcium oxalate increases activity EXP E RGD:6480464 20191114 CTD MESH:D002129 Calcium Oxalate results in increased activity of CASP3 protein PMID:25446497
12072547 CASP3 caspase 3 gene CHEBI:60579 calcium oxalate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002129 Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP3 protein] PMID:25446497
12072547 CASP3 caspase 3 gene CHEBI:6538 loratadine increases activity EXP E RGD:6480464 20191114 CTD MESH:D017336 Loratadine results in increased activity of CASP3 protein PMID:20570632
12072547 CASP3 caspase 3 gene CHEBI:9241 spironolactone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in decreased expression of CASP3 protein PMID:20082611
12072547 CASP3 caspase 3 gene CHEBI:9453 Terfenadine increases activity EXP E RGD:6480464 20191114 CTD MESH:D016593 Terfenadine results in increased activity of CASP3 protein PMID:20570632
12073341 TMEM45A transmembrane protein 45A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMEM45A mRNA PMID:38866337
12073966 SGK1 serum/glucocorticoid regulated kinase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SGK1 mRNA PMID:38866337
12074068 VIM vimentin gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of VIM mRNA; ochratoxin A results in increased expression of VIM protein PMID:33543323
12074068 VIM vimentin gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of VIM mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of VIM protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of VIM protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of VIM protein] PMID:33543323
12074886 BCL2 BCL2 apoptosis regulator gene CHEBI:17823 calcitriol affects expression EXP E RGD:6480464 20191114 CTD MESH:D002117 Calcitriol affects the expression of BCL2 protein PMID:16080513
12074886 BCL2 BCL2 apoptosis regulator gene CHEBI:192461 toosendanin decreases expression EXP E RGD:6480464 20240604 CTD MESH:C036454 toosendanin results in decreased expression of BCL2 mRNA; toosendanin results in decreased expression of BCL2 protein PMID:36809669
12074886 BCL2 BCL2 apoptosis regulator gene CHEBI:9241 spironolactone increases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in increased expression of BCL2 protein PMID:20082611
12074928 LATS2 large tumor suppressor kinase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LATS2 mRNA PMID:38866337
12075125 GNG3 G protein subunit gamma 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GNG3 mRNA PMID:38866337
12075184 FAS Fas cell surface death receptor gene CHEBI:3441 carvedilol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased expression of FAS PMID:12875697
12075682 LCN8 lipocalin 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LCN8 mRNA PMID:38866337
12075753 CDC42EP3 CDC42 effector protein 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CDC42EP3 mRNA PMID:38866337
12075858 CTCF CCCTC-binding factor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CTCF mRNA PMID:38866337
12076166 RHOBTB1 Rho related BTB domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RHOBTB1 mRNA PMID:38866337
12076208 MYPN myopalladin gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of MYPN mRNA PMID:27255383
12076782 GSAP gamma-secretase activating protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GSAP mRNA PMID:38866337
12077453 CCL17 C-C motif chemokine ligand 17 gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of CCL17 promoter PMID:33763461
12077453 CCL17 C-C motif chemokine ligand 17 gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of CCL17 promoter PMID:33763461
12077464 UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 gene CHEBI:46195 paracetamol increases glucuronidation EXP E RGD:6480464 20191114 CTD MESH:D000082 UGT1A6 protein results in increased glucuronidation of Acetaminophen PMID:11903872
12077495 MAP3K5 mitogen-activated protein kinase kinase kinase 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAP3K5 mRNA PMID:38866337
12077846 CPXM1 carboxypeptidase X, M14 family member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CPXM1 mRNA PMID:38866337
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:17747 bis(2-ethylhexyl) phthalate increases activity EXP E RGD:6480464 20191114 CTD MESH:D004051 Diethylhexyl Phthalate results in increased activity of NR1I3 protein PMID:27732639
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:223316 (+)-artemisinin increases activity EXP E RGD:6480464 20191114 CTD MESH:C031327 artemisinin results in increased activity of NR1I3 protein; artemisinin results in increased activity of NR1I3 protein alternative form; artemisinin results in increased activity of NR1I3 protein mutant form PMID:21778469|PMID:27732639
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:223316 (+)-artemisinin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C031327 androstan-3-ol inhibits the reaction [artemisinin results in increased activity of NR1I3 protein mutant form]; artemisinin inhibits the reaction [androstan-3-ol results in decreased activity of NR1I3 protein alternative form]; artemisinin inhibits the reaction [Imidazoles results in decreased activity of NR1I3 protein alternative form]; Imidazoles inhibits the reaction [artemisinin results in increased activity of NR1I3 protein mutant form] PMID:21778469
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:24780 imidazoles decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007093 Imidazoles results in decreased activity of NR1I3 protein alternative form PMID:21778469
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:24780 imidazoles multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007093 artemisinin inhibits the reaction [Imidazoles results in decreased activity of NR1I3 protein alternative form]; Imidazoles inhibits the reaction [artemisinin results in increased activity of NR1I3 protein mutant form] PMID:21778469
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:35727 triazoles increases activity EXP E RGD:6480464 20191114 CTD MESH:D014230 Triazoles results in increased activity of NR1I3 protein alternative form PMID:21778469
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:3764 clotrimazole affects binding EXP E RGD:6480464 20191114 CTD MESH:D003022 Clotrimazole binds to NR1I3 protein PMID:21778469
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:3764 clotrimazole increases activity EXP E RGD:6480464 20191114 CTD MESH:D003022 Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein mutant form PMID:21778469|PMID:27732639
12077895 NR1I3 nuclear receptor subfamily 1 group I member 3 gene CHEBI:47318 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases activity EXP E RGD:6480464 20191114 CTD MESH:C475093 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein mutant form PMID:21778469
12078136 LOC477556 glutathione S-transferase theta-1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20250401 CTD MESH:D010634 Phenobarbital results in decreased expression of GSTT1 mRNA PMID:19952500
12078870 NUP93 nucleoporin 93 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NUP93 mRNA PMID:38866337
12078996 ACKR2 atypical chemokine receptor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACKR2 mRNA PMID:38866337
12079085 CD3G CD3 gamma subunit of T-cell receptor complex gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CD3G mRNA PMID:38866337
12079236 ELOVL7 ELOVL fatty acid elongase 7 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ELOVL7 mRNA PMID:38866337
12079305 CPM carboxypeptidase M gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CPM mRNA PMID:38866337
12079637 PTPN13 protein tyrosine phosphatase non-receptor type 13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PTPN13 mRNA PMID:38866337
12079702 IL6 interleukin 6 gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20220405 CTD MESH:D008070 Lipopolysaccharides results in increased expression of IL6 mRNA PMID:32899721
12079702 IL6 interleukin 6 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20220405 CTD MESH:D008070 arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] PMID:32899721
12079702 IL6 interleukin 6 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20191114 CTD MESH:D000666 Amphotericin B results in increased expression of IL6 protein PMID:24105867
12079702 IL6 interleukin 6 gene CHEBI:2682 amphotericin B multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000666 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of IL6 protein] PMID:24105867
12079702 IL6 interleukin 6 gene CHEBI:29866 arsenite(3-) multiple interactions EXP E RGD:6480464 20220405 CTD MESH:C015001 arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] PMID:32899721
12079702 IL6 interleukin 6 gene CHEBI:47495 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases expression EXP E RGD:6480464 20191114 CTD MESH:C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of IL6 protein PMID:24105867
12079702 IL6 interleukin 6 gene CHEBI:47495 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of IL6 protein] PMID:24105867
12079702 IL6 interleukin 6 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of IL6 mRNA PMID:33543323
12079702 IL6 interleukin 6 gene CHEBI:7719 ochratoxin A increases secretion EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased secretion of IL6 protein PMID:33543323
12080881 NFKBIA NFKB inhibitor alpha gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [TNFSF11 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] PMID:21239502
12080881 NFKBIA NFKB inhibitor alpha gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of NFKBIA mRNA PMID:22747577
12081468 MCL1 MCL1 apoptosis regulator, BCL2 family member gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MCL1 mRNA PMID:38866337
12082040 NT5E 5'-nucleotidase ecto gene CHEBI:3441 carvedilol increases activity EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in increased activity of NT5E protein PMID:15148268
12082115 ADHFE1 alcohol dehydrogenase iron containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ADHFE1 mRNA PMID:38866337
12082585 NPTX2 neuronal pentraxin 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NPTX2 mRNA PMID:38866337
12082943 ZNF445 zinc finger protein 445 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZNF445 mRNA PMID:38866337
12083046 FHOD3 formin homology 2 domain containing 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FHOD3 mRNA PMID:38866337
12083733 HTR2B 5-hydroxytryptamine receptor 2B gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of HTR2B mRNA PMID:22747577
12083880 MYL5 myosin light chain 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MYL5 mRNA PMID:38866337
12084426 IL13RA1 interleukin 13 receptor subunit alpha 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IL13RA1 mRNA PMID:38866337
12084455 HSPA9 heat shock protein family A (Hsp70) member 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HSPA9 mRNA PMID:38866337
12084565 RRAS2 RAS related 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RRAS2 mRNA PMID:38866337
12084584 ALCAM activated leukocyte cell adhesion molecule gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ALCAM mRNA PMID:38866337
12085059 LOC100687713 BUB3-interacting and GLEBS motif-containing protein ZNF207 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZNF207 mRNA PMID:38866337
12085278 PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PIP4K2C mRNA PMID:38866337
12085405 B4GALT7 beta-1,4-galactosyltransferase 7 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of B4GALT7 mRNA PMID:22747577
12085432 DSEL dermatan sulfate epimerase like gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DSEL mRNA PMID:38866337
12085513 LRP8 LDL receptor related protein 8 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of LRP8 mRNA PMID:22747577
12085621 JAML junction adhesion molecule like gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of JAML mRNA PMID:22747577
12085709 PLIN1 perilipin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PLIN1 mRNA PMID:38866337
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:16240 hydrogen peroxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein PMID:23816505
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] PMID:23816505
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005978 Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein] PMID:23816505
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:26710 sodium chloride increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased phosphorylation of MAPK8 protein PMID:23816505
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein] PMID:23816505
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein] PMID:23816505
12085800 MAPK8 mitogen-activated protein kinase 8 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein] PMID:23816505
12085832 GPR20 G protein-coupled receptor 20 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GPR20 mRNA PMID:38866337
12085880 ACAD9 acyl-CoA dehydrogenase family member 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACAD9 mRNA PMID:38866337
12085918 LOC478702 tubulin beta-2B chain gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of TUBB2B mRNA PMID:27255383
12086222 SHC2 SHC adaptor protein 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SHC2 mRNA PMID:38866337
12086515 CXCL8 C-X-C motif chemokine ligand 8 gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL8 protein] PMID:18339021
12086515 CXCL8 C-X-C motif chemokine ligand 8 gene CHEBI:17883 hydrogen chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in increased expression of CXCL8 protein PMID:18339021
12086515 CXCL8 C-X-C motif chemokine ligand 8 gene CHEBI:17883 hydrogen chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006851 Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL8 protein] PMID:18339021
12086515 CXCL8 C-X-C motif chemokine ligand 8 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CXCL8 mRNA PMID:38866337
12086958 EIF3A eukaryotic translation initiation factor 3 subunit A gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of EIF3A protein PMID:22747577
12087412 CIDEA cell death inducing DFFA like effector a gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CIDEA mRNA PMID:38866337
12087520 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 [Ranolazine co-treated with Enalapril] affects the expression of ATP2A2 protein PMID:18820026
12087520 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene CHEBI:6904 metoprolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008790 [Ranolazine co-treated with Metoprolol] affects the expression of ATP2A2 protein PMID:18820026
12087520 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene CHEBI:87681 ranolazine affects expression EXP E RGD:6480464 20191114 CTD MESH:D000069458 Ranolazine affects the expression of ATP2A2 protein PMID:18820026
12087520 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 gene CHEBI:87681 ranolazine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069458 [Ranolazine co-treated with Enalapril] affects the expression of ATP2A2 protein; [Ranolazine co-treated with Metoprolol] affects the expression of ATP2A2 protein PMID:18820026
12087575 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of HNRNPA2B1 protein PMID:32991862
12087575 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HNRNPA2B1 mRNA PMID:38866337
12087674 EEF2 eukaryotic translation elongation factor 2 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of EEF2 protein PMID:32991862
12087720 MTARC2 mitochondrial amidoxime reducing component 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MTARC2 mRNA PMID:38866337
12087741 MAP2K6 mitogen-activated protein kinase kinase 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAP2K6 mRNA PMID:38866337
12087943 STXBP6 syntaxin binding protein 6 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of STXBP6 mRNA PMID:38866337
12088596 HOXA1 homeobox A1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HOXA1 mRNA PMID:38866337
12089187 CEP89 centrosomal protein 89 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CEP89 mRNA PMID:38866337
12089460 ABCA5 ATP binding cassette subfamily A member 5 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ABCA5 mRNA PMID:22747577
12090555 STX11 syntaxin 11 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of STX11 mRNA PMID:38866337
12090670 DERL2 derlin 2 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of DERL2 mRNA PMID:27255383
12091142 F13A1 coagulation factor XIII A chain gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of F13A1 mRNA PMID:38866337
12091856 ESR1 estrogen receptor 1 gene CHEBI:16469 17beta-estradiol affects expression EXP E RGD:6480464 20191114 CTD MESH:D004958 Estradiol affects the expression of ESR1 protein PMID:16483645
12091856 ESR1 estrogen receptor 1 gene CHEBI:17026 progesterone affects expression EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone affects the expression of ESR1 protein PMID:16483645
12092478 CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CITED1 mRNA PMID:38866337
12092660 EDNRA endothelin receptor type A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of EDNRA mRNA PMID:38866337
12093199 ANK1 ankyrin 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of ANK1 mRNA PMID:27255383
12093782 PDK4 pyruvate dehydrogenase kinase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PDK4 mRNA PMID:38866337
12094666 KCTD1 potassium channel tetramerization domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KCTD1 mRNA PMID:38866337
12095017 DUSP13B dual specificity phosphatase 13B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DUSP13 mRNA PMID:38866337
12095224 IMMP2L inner mitochondrial membrane peptidase subunit 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of IMMP2L mRNA PMID:22747577
12095241 RALGAPA1 Ral GTPase activating protein catalytic subunit alpha 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RALGAPA1 mRNA PMID:38866337
12095504 PRDX6 peroxiredoxin 6 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of PRDX6 protein PMID:19952500
12095504 PRDX6 peroxiredoxin 6 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of PRDX6 protein PMID:19952500
12095793 FKBP11 FKBP prolyl isomerase 11 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FKBP11 mRNA PMID:38866337
12095823 TMEM138 transmembrane protein 138 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMEM138 mRNA PMID:38866337
12096923 VPS41 VPS41 subunit of HOPS complex gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS41 mRNA PMID:27255383
12097183 TGFBR3 transforming growth factor beta receptor 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TGFBR3 mRNA PMID:38866337
12097421 SLCO1B2 solute carrier organic anion transporter family member 1B2 gene CHEBI:135946 sincalide increases transport EXP E RGD:6480464 20191114 CTD MESH:D012844 SLCO1B3 protein results in increased transport of Sincalide PMID:20079461
12097421 SLCO1B2 solute carrier organic anion transporter family member 1B2 gene CHEBI:17474 estrone 3-sulfate increases transport EXP E RGD:6480464 20191114 CTD MESH:C017296 SLCO1B3 protein results in increased transport of estrone sulfate PMID:20079461
12097421 SLCO1B2 solute carrier organic anion transporter family member 1B2 gene CHEBI:28865 taurocholic acid increases transport EXP E RGD:6480464 20191114 CTD MESH:D013656 SLCO1B3 protein results in increased transport of Taurocholic Acid PMID:20079461
12097421 SLCO1B2 solute carrier organic anion transporter family member 1B2 gene CHEBI:63836 bromosulfophthalein increases transport EXP E RGD:6480464 20191114 CTD MESH:D013448 SLCO1B3 protein results in increased transport of Sulfobromophthalein PMID:20079461
12097421 SLCO1B2 solute carrier organic anion transporter family member 1B2 gene CHEBI:73356 DPDPE increases transport EXP E RGD:6480464 20191114 CTD MESH:D020881 SLCO1B3 protein results in increased transport of Enkephalin, D-Penicillamine (2,5)- PMID:20079461
12097421 SLCO1B2 solute carrier organic anion transporter family member 1B2 gene CHEBI:791 17beta-estradiol 17-glucosiduronic acid increases transport EXP E RGD:6480464 20191114 CTD MESH:C025483 SLCO1B3 protein results in increased transport of estradiol-17 beta-glucuronide PMID:20079461
12097528 SEMA3D semaphorin 3D gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SEMA3D mRNA PMID:38866337
12098278 DSE dermatan sulfate epimerase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DSE mRNA PMID:38866337
12098649 GLS glutaminase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GLS mRNA PMID:38866337
12098737 LOC609402 hemoglobin subunit beta-like gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20250107 CTD MESH:C526575 masitinib results in increased expression of HBG1 mRNA PMID:22747577
12098749 PXYLP1 2-phosphoxylose phosphatase 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ACPL2 mRNA PMID:22747577
12098816 GTF3C4 general transcription factor IIIC subunit 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GTF3C4 mRNA PMID:38866337
12099049 HIF3A hypoxia inducible factor 3 subunit alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HIF3A mRNA PMID:38866337
12099137 ANXA6 annexin A6 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ANXA6 protein PMID:22747577
12099413 PPFIBP2 PPFIA binding protein 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPFIBP2 mRNA PMID:38866337
12099590 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPM1D mRNA PMID:38866337
12100173 ANXA1 annexin A1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ANXA1 protein PMID:22747577
12100237 SPRYD4 SPRY domain containing 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SPRYD4 mRNA PMID:38866337
12101384 HEBP2 heme binding protein 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of HEBP2 mRNA PMID:22747577
12101396 DLST dihydrolipoamide S-succinyltransferase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DLST mRNA PMID:38866337
12101396 DLST dihydrolipoamide S-succinyltransferase gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of DLST protein PMID:19952500
12101836 CATSPER3 cation channel sperm associated 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CATSPER3 mRNA PMID:38866337
12101859 GCNT1 glucosaminyl (N-acetyl) transferase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GCNT1 mRNA PMID:38866337
12101885 ATG4D autophagy related 4D cysteine peptidase gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of ATG4D mRNA PMID:27255383
12101969 CORO1A coronin 1A gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CORO1A protein PMID:22747577
12102132 THADA THADA armadillo repeat containing gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of THADA mRNA PMID:38866337
12102553 PCM1 pericentriolar material 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PCM1 mRNA PMID:22747577
12102965 PRUNE1 prune exopolyphosphatase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PRUNE1 mRNA PMID:38866337
12103247 RABEPK Rab9 effector protein with kelch motifs gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of RABEPK mRNA PMID:27255383
12103267 C1QTNF3 C1q and TNF related 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of C1QTNF3 mRNA PMID:38866337
12104110 SSH2 slingshot protein phosphatase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SSH2 mRNA PMID:38866337
12104339 MIR29B-1 microRNA mir-29b-1 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR29B-1 PMID:40036580
12104718 PRPS2 phosphoribosyl pyrophosphate synthetase 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of PRPS2 mRNA PMID:22747577
12104989 THAP11 THAP domain containing 11 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of THAP11 mRNA PMID:38866337
12105135 IFT70B intraflagellar transport 70B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IFT70B mRNA PMID:38866337
12105149 C20H19orf44 chromosome 20 C19orf44 homolog gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of C20H19ORF44 mRNA PMID:38866337
12105362 GLCE glucuronic acid epimerase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GLCE mRNA PMID:38866337
12105709 OR6Q1 olfactory receptor family 6 subfamily Q member 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of OR6AE1 mRNA PMID:38866337
12105831 SLC18A2 solute carrier family 18 member A2 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC18A2 mRNA] PMID:25419811
12105831 SLC18A2 solute carrier family 18 member A2 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC18A2 mRNA] PMID:25419811
12105831 SLC18A2 solute carrier family 18 member A2 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC18A2 mRNA] PMID:25419811
12105831 SLC18A2 solute carrier family 18 member A2 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC18A2 mRNA] PMID:25419811
12106395 AVP arginine vasopressin gene CHEBI:2453 acyclovir decreases activity EXP E RGD:6480464 20191114 CTD MESH:D000212 Acyclovir results in decreased activity of AVP protein PMID:2724137
12106395 AVP arginine vasopressin gene CHEBI:41879 dexamethasone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D003907 Dexamethasone results in decreased expression of AVP protein PMID:1934541
12106615 IKZF2 IKAROS family zinc finger 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IKZF2 mRNA PMID:38866337
12106872 ID1 inhibitor of DNA binding 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ID1 mRNA PMID:38866337
12107235 CIRBP cold inducible RNA binding protein gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CIRBP mRNA PMID:22747577
12107279 PGAM1 phosphoglycerate mutase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PGAM1 mRNA PMID:38866337
12107669 ERLIN2 ER lipid raft associated 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ERLIN2 mRNA PMID:38866337
12107715 RAB6A RAB6A, member RAS oncogene family gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RAB6A mRNA PMID:38866337
12107850 LENG9 leukocyte receptor cluster member 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LENG9 mRNA PMID:38866337
12108225 VPS29 VPS29 retromer complex component gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS29 mRNA PMID:27255383
12108268 TCEA3 transcription elongation factor A3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TCEA3 mRNA PMID:38866337
12108584 CYB5D1 cytochrome b5 domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CYB5D1 mRNA PMID:38866337
12108935 FKBP5 FKBP prolyl isomerase 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FKBP5 mRNA PMID:38866337
12109610 MAPK13 mitogen-activated protein kinase 13 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MAPK13 mRNA PMID:38866337
12109750 AKAP8 A-kinase anchoring protein 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AKAP8 mRNA PMID:38866337
12110037 PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of PCK2 protein PMID:19952500
12110802 RAI14 retinoic acid induced 14 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RAI14 mRNA PMID:38866337
12111199 FADD Fas associated via death domain gene CHEBI:132230 marbofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:C080260 marbofloxacin results in increased expression of FADD mRNA PMID:31005593
12111206 IL31 interleukin 31 gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA] PMID:33763461
12111206 IL31 interleukin 31 gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA] PMID:33763461
12111467 MIR31 microRNA mir-31 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR31 PMID:40036580
12111640 USO1 USO1 vesicle transport factor gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of USO1 mRNA PMID:27255383
12111949 FAM180A family with sequence similarity 180 member A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM180A mRNA PMID:38866337
12112200 SYTL2 synaptotagmin like 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SYTL2 mRNA PMID:38866337
12112287 TRPV1 transient receptor potential cation channel subfamily V member 1 gene CHEBI:3374 capsaicin increases activity EXP E RGD:6480464 20191114 CTD MESH:D002211 Capsaicin results in increased activity of TRPV1 protein PMID:17392452
12112287 TRPV1 transient receptor potential cation channel subfamily V member 1 gene CHEBI:3374 capsaicin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002211 JYL 1421 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] PMID:17392452
12113038 STX4 syntaxin 4 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of STX4 mRNA PMID:27255383
12113445 CPS1 carbamoyl-phosphate synthase 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of CPS1 protein PMID:19952500
12113986 CASP4 caspase 4, apoptosis-related cysteine peptidase gene CHEBI:7719 ochratoxin A increases cleavage EXP E RGD:6480464 20250325 CTD MESH:C025589 ochratoxin A results in increased cleavage of CASP1 protein PMID:33543323
12113986 CASP4 caspase 4, apoptosis-related cysteine peptidase gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20250325 CTD MESH:C025589 ochratoxin A results in increased expression of CASP1 mRNA PMID:33543323
12113986 CASP4 caspase 4, apoptosis-related cysteine peptidase gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20250325 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of ACTA2 mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of ACTA2 protein]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of CASP1 mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of GSDMD mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of GSDMD protein]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of IL18 mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of IL1B mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of IL1B protein]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 protein]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of VIM mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of VIM protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased cleavage of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of CASP1 mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of CASP1 mRNA] PMID:33543323
12114155 DBNDD2 dysbindin domain containing 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DBNDD2 mRNA PMID:38866337
12114361 GOLGA2 golgin A2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GOLGA2 mRNA PMID:38866337
12114548 GGT1 gamma-glutamyltransferase 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of GGT1 mRNA PMID:22747577
12114717 RASSF4 Ras association domain family member 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RASSF4 mRNA PMID:38866337
12114876 SLC10A4 solute carrier family 10 member 4 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC10A4 mRNA] PMID:25419811
12114876 SLC10A4 solute carrier family 10 member 4 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC10A4 mRNA] PMID:25419811
12114876 SLC10A4 solute carrier family 10 member 4 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC10A4 mRNA] PMID:25419811
12114876 SLC10A4 solute carrier family 10 member 4 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC10A4 mRNA] PMID:25419811
12115043 NANS N-acetylneuraminate synthase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NANS mRNA PMID:38866337
12115330 TBC1D22B TBC1 domain family member 22B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TBC1D22B mRNA PMID:38866337
12115416 PSMD6 proteasome 26S subunit, non-ATPase 6 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of PSMD6 protein PMID:22747577
12115725 PNMA8A PNMA family member 8A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PNMA8A mRNA PMID:38866337
12115825 RERG RAS like estrogen regulated growth inhibitor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RERG mRNA PMID:38866337
12115903 NGF nerve growth factor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NGF mRNA PMID:38866337
12116012 CCDC170 coiled-coil domain containing 170 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CCDC170 mRNA PMID:38866337
12116079 AP3S2 adaptor related protein complex 3 subunit sigma 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AP3S2 mRNA PMID:38866337
12116424 CDKN2A cyclin dependent kinase inhibitor 2A gene CHEBI:64090 tert-butyl hydroperoxide decreases expression EXP E RGD:6480464 20220118 CTD MESH:D020122 tert-Butylhydroperoxide results in decreased expression of CDKN2A protein PMID:14729356
12116574 IL18 interleukin 18 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of IL18 mRNA PMID:33543323
12116574 IL18 interleukin 18 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of IL18 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of IL18 mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of IL18 mRNA] PMID:33543323
12116636 CD74 CD74 molecule gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CD74 mRNA PMID:38866337
12117086 OR4S7 olfactory receptor family 4 subfamily S member 7 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of OR4S7 mRNA PMID:38866337
12117362 TNFSF11 TNF superfamily member 11 gene CHEBI:27881 resveratrol decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in decreased susceptibility to TNFSF11 protein PMID:21239502
12117362 TNFSF11 TNF superfamily member 11 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] inhibits the reaction [TNFSF11 protein results in increased acetylation of and results in increased activity of RELA protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in decreased expression of RUNX2 protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in increased acetylation of and results in increased localization of and results in increased activity of RELA protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in increased localization of and results in increased activity of RELA protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] PMID:21239502
12117370 LRIT3 leucine rich repeat, Ig-like and transmembrane domains 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LRIT3 mRNA PMID:38866337
12117646 TPR translocated promoter region, nuclear basket protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TPR mRNA PMID:38866337
12118927 LIN7C lin-7 homolog C, crumbs cell polarity complex component gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of LIN7C mRNA PMID:22747577
12119413 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250715 CTD MESH:D000666 Amphotericin B results in increased expression of PRKACG protein PMID:24105867
12119413 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene CHEBI:2682 amphotericin B multiple interactions EXP E RGD:6480464 20250715 CTD MESH:D000666 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of PRKACG protein] PMID:24105867
12119413 PRKACA protein kinase cAMP-activated catalytic subunit alpha gene CHEBI:47495 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP E RGD:6480464 20250715 CTD MESH:C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of PRKACG protein] PMID:24105867
12119451 TP53 tumor protein p53 gene CHEBI:192461 toosendanin increases expression EXP E RGD:6480464 20240604 CTD MESH:C036454 toosendanin results in increased expression of TP53 mRNA; toosendanin results in increased expression of TP53 protein PMID:36809669
12119769 LACTB lactamase beta gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LACTB mRNA PMID:38866337
12119872 POMT1 protein O-mannosyltransferase 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of POMT1 mRNA PMID:22747577
12120131 LEP leptin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LEP mRNA PMID:38866337
12120274 CHMP5 charged multivesicular body protein 5 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of CHMP5 mRNA PMID:27255383
12120440 KLK14 kallikrein related peptidase 14 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KLK14 mRNA PMID:38866337
12120500 ACP3 acid phosphatase 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ACP3 mRNA PMID:38866337
12120555 TRPM8 transient receptor potential cation channel subfamily M member 8 gene CHEBI:22984 calcium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [mustard oil results in increased activity of TRPM8 protein] which results in increased transport of Calcium; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[mustard oil results in increased activity of TRPM8 protein] which results in increased transport of Calcium] PMID:16386244
12120555 TRPM8 transient receptor potential cation channel subfamily M member 8 gene CHEBI:25187 p-menthan-3-ol increases activity EXP E RGD:6480464 20191114 CTD MESH:D008610 Menthol results in increased activity of TRPM8 protein PMID:16386244
12120555 TRPM8 transient receptor potential cation channel subfamily M member 8 gene CHEBI:25187 p-menthan-3-ol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008610 [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium] PMID:16386244
12120555 TRPM8 transient receptor potential cation channel subfamily M member 8 gene CHEBI:29320 calcium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 [icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium; [mustard oil results in increased activity of TRPM8 protein] which results in increased transport of Calcium; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[icilin results in increased activity of TRPM8 protein] which results in increased transport of Calcium]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[Menthol results in increased activity of TRPM8 protein] which results in increased transport of Calcium]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [[mustard oil results in increased activity of TRPM8 protein] which results in increased transport of Calcium] PMID:16386244
12120906 TRADD TNFRSF1A associated via death domain gene CHEBI:132230 marbofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:C080260 marbofloxacin results in increased expression of TRADD mRNA PMID:31005593
12120906 TRADD TNFRSF1A associated via death domain gene CHEBI:132230 marbofloxacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C080260 TNFRSF1A mRNA promotes the reaction [marbofloxacin results in increased expression of TRADD mRNA] PMID:31005593
12120906 TRADD TNFRSF1A associated via death domain gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of TRADD mRNA PMID:24582689
12120906 TRADD TNFRSF1A associated via death domain gene CHEBI:7731 ofloxacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015242 TNFRSF1A mutant form inhibits the reaction [Ofloxacin results in increased expression of TRADD mRNA] PMID:24582689
12121005 SMIM1 small integral membrane protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SMIM1 mRNA PMID:38866337
12121151 ABCC5 ATP binding cassette subfamily C member 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ABCC5 mRNA PMID:38866337
12121321 GSTT2B glutathione S-transferase theta 2B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GSTT2B mRNA PMID:38866337
12121321 GSTT2B glutathione S-transferase theta 2B gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20250715 CTD MESH:D010634 Phenobarbital results in decreased expression of GSTT2 mRNA PMID:19952500
12121525 TMED1 transmembrane p24 trafficking protein 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TMED1 mRNA PMID:27255383
12121678 SFT2D2 SFT2 domain containing 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of SFT2D2 mRNA PMID:22747577
12121940 ASNS asparagine synthetase (glutamine-hydrolyzing) gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ASNS mRNA PMID:38866337
12122366 CD72 CD72 molecule gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CD72 mRNA PMID:38866337
12122424 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PIK3R1 mRNA PMID:38866337
12122621 MIR151 microRNA mir-151 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR151 PMID:40036580
12122857 PGR progesterone receptor gene CHEBI:17026 progesterone affects binding EXP E RGD:6480464 20191114 CTD MESH:D011374 Progesterone binds to PGR protein PMID:16054490
12122857 PGR progesterone receptor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PGR mRNA PMID:38866337
12122897 TUBG1 tubulin, gamma 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TUBG1 mRNA PMID:27255383
12123137 ACIN1 apoptotic chromatin condensation inducer 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACIN1 mRNA PMID:38866337
12123764 EFEMP1 EGF containing fibulin extracellular matrix protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EFEMP1 mRNA PMID:38866337
12123831 ACSL1 acyl-CoA synthetase long chain family member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACSL1 mRNA PMID:38866337
12123913 SEPTIN11 septin 11 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SEPTIN11 mRNA PMID:38866337
12123938 KNG1 kininogen 1 gene CHEBI:16480 nitric oxide increases activity EXP E RGD:6480464 20191114 CTD MESH:D009569 Nitric Oxide deficiency results in increased activity of KNG1 protein modified form PMID:10805402
12123938 KNG1 kininogen 1 gene CHEBI:25549 nitrites increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:D009573 KNG1 protein modified form results in increased chemical synthesis of Nitrites PMID:17644579
12124407 CDK8 cyclin dependent kinase 8 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CDK8 mRNA PMID:38866337
12124520 TIMP1 TIMP metallopeptidase inhibitor 1 gene CHEBI:9241 spironolactone increases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in increased expression of TIMP1 protein PMID:20082611
12124530 MEIS1 Meis homeobox 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MEIS1 mRNA PMID:38866337
12125427 EEF2K eukaryotic elongation factor 2 kinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EEF2K mRNA PMID:38866337
12125525 TPM2 tropomyosin 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TPM2 mRNA PMID:38866337
12125560 CNN1 calponin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CNN1 mRNA PMID:38866337
12125759 CFTR CF transmembrane conductance regulator gene CHEBI:28088 genistein decreases activity EXP E RGD:6480464 20191114 CTD MESH:D019833 Genistein results in decreased activity of CFTR protein PMID:15496164
12125759 CFTR CF transmembrane conductance regulator gene CHEBI:34457 5-Nitro-2-(3-phenylpropylamino)benzoic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:C058176 5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein PMID:15496164
12125759 CFTR CF transmembrane conductance regulator gene CHEBI:34795 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015056 [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein PMID:15161604
12125759 CFTR CF transmembrane conductance regulator gene CHEBI:5441 glyburide decreases activity EXP E RGD:6480464 20191114 CTD MESH:D005905 Glyburide results in decreased activity of CFTR protein PMID:15496164
12125759 CFTR CF transmembrane conductance regulator gene CHEBI:84612 8-(4-chlorophenylthio)-cAMP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C015929 [1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein PMID:15161604
12125795 THEM5 thioesterase superfamily member 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of THEM5 mRNA PMID:38866337
12127651 GXYLT1 glucoside xylosyltransferase 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of GXYLT1 mRNA PMID:22747577
12128020 MIR23A microRNA mir-23a gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR23A PMID:40036580
12129208 ZAR1L zygote arrest 1 like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZAR1L mRNA PMID:38866337
12129699 SEMA6D semaphorin 6D gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SEMA6D mRNA PMID:38866337
12129746 MIR29C-2 microRNA mir-29c-2 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR29C PMID:40036580
12130565 PECAM1 platelet and endothelial cell adhesion molecule 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PECAM1 mRNA PMID:22747577
12130594 EBF3 EBF transcription factor 3 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of EBF3 mRNA] PMID:25419811
12130594 EBF3 EBF transcription factor 3 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of EBF3 mRNA] PMID:25419811
12130594 EBF3 EBF transcription factor 3 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of EBF3 mRNA] PMID:25419811
12130594 EBF3 EBF transcription factor 3 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of EBF3 mRNA] PMID:25419811
12131516 ZNF23 zinc finger protein 23 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ZNF23 mRNA PMID:22747577
12131622 FAM72A family with sequence similarity 72 member A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FAM72A mRNA PMID:38866337
12132159 ELSPBP1 epididymal sperm binding protein 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ELSPBP1 mRNA PMID:22747577
12132858 TSPAN2 tetraspanin 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TSPAN2 mRNA PMID:22747577
12132965 CNIH1 cornichon family AMPA receptor auxiliary protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CNIH1 mRNA PMID:38866337
12133286 HAUS8 HAUS augmin like complex subunit 8 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HAUS8 mRNA PMID:38866337
12133381 SMTN smoothelin gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of SMTN mRNA PMID:27255383
12133457 TTLL5 tubulin tyrosine ligase like 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TTLL5 mRNA PMID:38866337
12133580 ASB9 ankyrin repeat and SOCS box containing 9 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ASB9 mRNA PMID:38866337
12133742 GADD45B growth arrest and DNA damage inducible beta gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GADD45B mRNA PMID:38866337
12133906 F3 coagulation factor III, tissue factor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of F3 mRNA PMID:38866337
12134050 TMEM182 transmembrane protein 182 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM182 mRNA PMID:38866337
12134198 ALS2 alsin Rho guanine nucleotide exchange factor ALS2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ALS2 mRNA PMID:38866337
12134695 DNAJC17 DnaJ heat shock protein family (Hsp40) member C17 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DNAJC17 mRNA PMID:38866337
12135059 FAM234B family with sequence similarity 234 member B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM234B mRNA PMID:38866337
12135324 GKN1 gastrokine 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of GKN1 mRNA PMID:22747577
12135641 EIF4A1 eukaryotic translation initiation factor 4A1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of EIF4A1 protein PMID:22747577
12135758 SBF2 SET binding factor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SBF2 mRNA PMID:38866337
12136121 FAM13C family with sequence similarity 13 member C gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FAM13C mRNA PMID:38866337
12136377 UBE2E2 ubiquitin conjugating enzyme E2 E2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of UBE2E2 mRNA PMID:38866337
12136452 FAM229A family with sequence similarity 229 member A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM229A mRNA PMID:38866337
12136644 NOLC1 nucleolar and coiled-body phosphoprotein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NOLC1 mRNA PMID:38866337
12136717 MIR194 microRNA mir-194 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR194 PMID:40036580
12136798 PAH phenylalanine hydroxylase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of PAH protein PMID:19952500
12136864 TUBA4A tubulin alpha 4a gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TUBA4A mRNA PMID:27255383
12136920 ASL argininosuccinate lyase gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of ASL protein PMID:19952500
12136920 ASL argininosuccinate lyase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of ASL protein PMID:19952500
12137188 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BUB1B mRNA PMID:38866337
12137219 FABP4 fatty acid binding protein 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FABP4 mRNA PMID:38866337
12137262 TMEM65 transmembrane protein 65 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMEM65 mRNA PMID:38866337
12137878 CLSPN claspin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CLSPN mRNA PMID:38866337
12137992 CYP26A1 cytochrome P450 family 26 subfamily A member 1 gene CHEBI:15367 all-trans-retinoic acid increases degradation EXP E RGD:6480464 20191114 CTD MESH:D014212 CYP26A1 protein results in increased degradation of Tretinoin PMID:17035595
12137992 CYP26A1 cytochrome P450 family 26 subfamily A member 1 gene CHEBI:15367 all-trans-retinoic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014212 CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN1 mRNA]; CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN4 mRNA]; CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of OCLN mRNA]; CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of TJP1 mRNA] PMID:17035595
12138233 ZKSCAN2 zinc finger with KRAB and SCAN domains 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZKSCAN2 mRNA PMID:38866337
12138460 GNAQ G protein subunit alpha q gene CHEBI:61048 ganglioside GM1 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005677 G(M1) Ganglioside inhibits the reaction [mastoparan results in increased activity of and affects the localization of GNAQ protein] PMID:21671308
12138460 GNAQ G protein subunit alpha q gene CHEBI:78496 mastoparan multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C037500 G(M1) Ganglioside inhibits the reaction [mastoparan results in increased activity of and affects the localization of GNAQ protein]; ganglioside, GD1a inhibits the reaction [mastoparan results in increased activity of and affects the localization of GNAQ protein]; mastoparan results in increased activity of and affects the localization of GNAQ protein PMID:21671308
12138962 ABCG2 ATP binding cassette subfamily G member 2 gene CHEBI:10106 zearalenone increases transport EXP E RGD:6480464 20191114 CTD MESH:D015025 ABCG2 protein results in increased transport of Zearalenone PMID:30576553
12138962 ABCG2 ATP binding cassette subfamily G member 2 gene CHEBI:5831 Hypaconitine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C058309 [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of hypaconitine PMID:23200901
12138962 ABCG2 ATP binding cassette subfamily G member 2 gene CHEBI:6773 Mesaconitine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C019470 [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of mesaconitine PMID:23200901
12139511 TPM4 tropomyosin 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TPM4 mRNA PMID:38866337
12139753 LRP6 LDL receptor related protein 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LRP6 mRNA PMID:38866337
12139784 ALDH18A1 aldehyde dehydrogenase 18 family member A1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ALDH18A1 mRNA PMID:38866337
12140526 PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPM1B mRNA PMID:38866337
12140683 MGST2 microsomal glutathione S-transferase 2 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of MGST2 mRNA PMID:19952500
12141041 LYRM1 LYR motif containing 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of LYRM1 mRNA PMID:22747577
12141175 EREG epiregulin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of EREG mRNA PMID:38866337
12141684 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAP4K4 mRNA PMID:38866337
12142127 CIART circadian associated repressor of transcription gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CIART mRNA PMID:38866337
12142351 STARD10 StAR related lipid transfer domain containing 10 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of STARD10 mRNA PMID:38866337
12142365 PYCARD PYD and CARD domain containing gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of PYCARD mRNA; ochratoxin A results in increased expression of PYCARD protein PMID:33543323
12142365 PYCARD PYD and CARD domain containing gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of PYCARD mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of PYCARD protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of PYCARD mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of PYCARD protein] PMID:33543323
12142458 MPEG1 macrophage expressed 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MPEG1 mRNA PMID:38866337
12142742 STOX1 storkhead box 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of STOX1 mRNA PMID:22747577
12142850 CD5L CD5 molecule like gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CD5L mRNA PMID:22747577
12143071 RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RTF1 mRNA PMID:38866337
12143356 MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of MICAL1 mRNA PMID:27255383
12143895 PFDN2 prefoldin subunit 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PFDN2 mRNA PMID:38866337
12143922 PRELID3A PRELI domain containing 3A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PRELID3A mRNA PMID:38866337
12144117 EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of EDEM2 mRNA PMID:22747577
12144154 SLC9A1 solute carrier family 9 member A1 gene CHEBI:30621 diarsenic trioxide increases expression EXP E RGD:6480464 20191114 CTD MESH:C006632 Arsenic Trioxide results in increased expression of SLC9A1 protein PMID:23236503
12144154 SLC9A1 solute carrier family 9 member A1 gene CHEBI:49900 arsenous acid increases expression EXP E RGD:6480464 20191114 CTD MESH:C032793 Arsenic Trioxide results in increased expression of SLC9A1 protein PMID:23236503
12144529 AADAT aminoadipate aminotransferase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AADAT mRNA PMID:38866337
12144681 TDRP testis development related protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TDRP mRNA PMID:38866337
12144726 FAM228B family with sequence similarity 228, member B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM228B mRNA PMID:38866337
12145238 DAZAP2 DAZ associated protein 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DAZAP2 mRNA PMID:38866337
12145444 ACAT2 acetyl-CoA acetyltransferase 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ACAT2 mRNA PMID:22747577
12145756 RALGAPB Ral GTPase activating protein non-catalytic subunit beta gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RALGAPB mRNA PMID:38866337
12146632 HRCT1 histidine rich carboxyl terminus 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HRCT1 mRNA PMID:38866337
12146852 TTN titin gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TTN mRNA PMID:27255383
12147254 POLR1B RNA polymerase I subunit B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of POLR1B mRNA PMID:38866337
12147301 CAT catalase gene CHEBI:36560 zinc oxide decreases activity EXP E RGD:6480464 20191114 CTD MESH:D015034 Zinc Oxide results in decreased activity of CAT protein PMID:28126643
12148011 YPEL4 yippee like 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of YPEL4 mRNA PMID:38866337
12148797 NIPAL2 NIPA like domain containing 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NIPAL2 mRNA PMID:38866337
12149100 RND1 Rho family GTPase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RND1 mRNA PMID:38866337
12149119 STRBP spermatid perinuclear RNA binding protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of STRBP mRNA PMID:38866337
12149344 TUT4 terminal uridylyl transferase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TUT4 mRNA PMID:38866337
12150253 TSNAXIP1 translin associated factor X interacting protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TSNAXIP1 mRNA PMID:38866337
12150845 HACD2 3-hydroxyacyl-CoA dehydratase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HACD2 mRNA PMID:38866337
12151468 PDE6H phosphodiesterase 6H gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PDE6H mRNA PMID:22747577
12151708 CYP2D15 cytochrome P450 family 2 subfamily D member 15 gene CHEBI:34593 Bufuralol affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:C010831 CYP2D6 protein affects the metabolism of bufuralol PMID:15801540
12151708 CYP2D15 cytochrome P450 family 2 subfamily D member 15 gene CHEBI:4470 dextromethorphan affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D003915 CYP2D15 affects the metabolism of Dextromethorphan PMID:7786018
12151708 CYP2D15 cytochrome P450 family 2 subfamily D member 15 gene CHEBI:47781 desipramine affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D003891 CYP2D15 affects the metabolism of Desipramine PMID:7786018
12151708 CYP2D15 cytochrome P450 family 2 subfamily D member 15 gene CHEBI:6904 metoprolol affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D008790 CYP2D15 affects the metabolism of Metoprolol PMID:7786018
12152101 SLC22A6 solute carrier family 22 member 6 gene CHEBI:43355 indoxyl sulfate multiple interactions EXP E RGD:6480464 20230404 CTD MESH:D007200 [Lansoprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican; [Omeprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican; [Pantoprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican PMID:36243147
12152101 SLC22A6 solute carrier family 22 member 6 gene CHEBI:6375 lansoprazole multiple interactions EXP E RGD:6480464 20230404 CTD MESH:D064747 [Lansoprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican PMID:36243147
12152101 SLC22A6 solute carrier family 22 member 6 gene CHEBI:77260 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions EXP E RGD:6480464 20230404 CTD MESH:D009853 [Omeprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican PMID:36243147
12152101 SLC22A6 solute carrier family 22 member 6 gene CHEBI:7772 omeprazole multiple interactions EXP E RGD:6480464 20230404 CTD MESH:D009853 [Omeprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican PMID:36243147
12152101 SLC22A6 solute carrier family 22 member 6 gene CHEBI:7915 pantoprazole multiple interactions EXP E RGD:6480464 20230404 CTD MESH:C064276 [Pantoprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican PMID:36243147
12152328 PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of PDHA1 mRNA PMID:22747577
12152996 TMT1A thiol methyltransferase 1A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of METTL7A mRNA PMID:38866337
12153322 DHRS2 dehydrogenase/reductase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DHRS2 mRNA PMID:38866337
12153803 CXCL12 C-X-C motif chemokine ligand 12 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CXCL12 mRNA PMID:38866337
12154022 PEX19 peroxisomal biogenesis factor 19 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of PEX19 mRNA PMID:27255383
12154073 LOC479912 glutathione S-transferase Mu 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20250401 CTD MESH:D002994 Clofibrate results in decreased expression of GSTM1 mRNA PMID:19952500
12154073 LOC479912 glutathione S-transferase Mu 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20250401 CTD MESH:D010634 Phenobarbital results in decreased expression of GSTM1 mRNA PMID:19952500
12154650 AP3S1 adaptor related protein complex 3 subunit sigma 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of AP3S1 mRNA PMID:27255383
12155305 CMA1 chymase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CMA1 mRNA PMID:38866337
12155517 MIR205 microRNA mir-205 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR205 PMID:40036580
12156331 BLID BH3-like motif containing, cell death inducer gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of BLID mRNA PMID:38866337
12156386 COPB2 COPI coat complex subunit beta 2 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of COPB2 mRNA PMID:27255383
12156508 SLC23A2 solute carrier family 23 member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC23A2 mRNA PMID:38866337
12157119 SLC25A47 solute carrier family 25 member 47 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC25A47 mRNA PMID:38866337
12157496 KDM5A lysine demethylase 5A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KDM5A mRNA PMID:38866337
12157586 ASS1 argininosuccinate synthase 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of ASS1 protein PMID:19952500
12157586 ASS1 argininosuccinate synthase 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of ASS1 protein PMID:19952500
12157823 TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TRARG1 mRNA PMID:38866337
12157970 MIR148A microRNA mir-148a gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR148A PMID:40036580
12158115 PEG3 paternally expressed 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PEG3 mRNA PMID:38866337
12158178 TCTN1 tectonic family member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TCTN1 mRNA PMID:38866337
12158239 ASH2L ASH2 like, histone lysine methyltransferase complex subunit gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ASH2L mRNA PMID:38866337
12158445 IRX6 iroquois homeobox 6 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of IRX6 protein PMID:22747577
12158493 ERAP1 endoplasmic reticulum aminopeptidase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ERAP1 mRNA PMID:38866337
12158616 LRRC59 leucine rich repeat containing 59 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LRRC59 mRNA PMID:38866337
12158997 REN renin gene CHEBI:135026 xibenolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006027 xibenolol inhibits the reaction [Isoproterenol results in increased activity of REN protein] PMID:6103674
12158997 REN renin gene CHEBI:145568 cilazapril monohydrate increases activity EXP E RGD:6480464 20200107 CTD MESH:D017315 Cilazapril results in increased activity of REN protein PMID:2419701
12158997 REN renin gene CHEBI:15551 prostaglandin E2 increases expression EXP E RGD:6480464 20191114 CTD MESH:D015232 Dinoprostone results in increased expression of REN protein PMID:495730
12158997 REN renin gene CHEBI:18357 (R)-noradrenaline increases activity EXP E RGD:6480464 20191114 CTD MESH:D009638 Norepinephrine results in increased activity of REN protein PMID:8952593
12158997 REN renin gene CHEBI:2668 amlodipine increases expression EXP E RGD:6480464 20191114 CTD MESH:D017311 Amlodipine results in increased expression of REN protein PMID:10218729
12158997 REN renin gene CHEBI:2682 amphotericin B decreases secretion EXP E RGD:6480464 20191114 CTD MESH:D000666 Amphotericin B results in decreased secretion of REN protein PMID:7391978
12158997 REN renin gene CHEBI:28787 nitroglycerin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D005996 Nitroglycerin results in decreased activity of REN protein PMID:8640982
12158997 REN renin gene CHEBI:2904 atenolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001262 Atenolol inhibits the reaction [Isoproterenol results in increased activity of REN protein] PMID:6103674
12158997 REN renin gene CHEBI:35457 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor increases activity EXP E RGD:6480464 20191114 CTD MESH:D000806 Angiotensin-Converting Enzyme Inhibitors results in increased activity of REN protein PMID:6257882
12158997 REN renin gene CHEBI:35457 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor increases secretion EXP E RGD:6480464 20191114 CTD MESH:D000806 Angiotensin-Converting Enzyme Inhibitors results in increased secretion of REN protein PMID:6185789
12158997 REN renin gene CHEBI:3757 clonidine (imino form) decreases activity EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in decreased activity of REN protein PMID:6991409
12158997 REN renin gene CHEBI:3757 clonidine (imino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in decreased secretion of and results in decreased activity of REN protein PMID:6248808
12158997 REN renin gene CHEBI:46631 clonidine decreases activity EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in decreased activity of REN protein PMID:6991409
12158997 REN renin gene CHEBI:46631 clonidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in decreased secretion of and results in decreased activity of REN protein PMID:6248808
12158997 REN renin gene CHEBI:46632 clonidine (amino form) decreases activity EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in decreased activity of REN protein PMID:6991409
12158997 REN renin gene CHEBI:46632 clonidine (amino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in decreased secretion of and results in decreased activity of REN protein PMID:6248808
12158997 REN renin gene CHEBI:472805 ouabain decreases secretion EXP E RGD:6480464 20191114 CTD MESH:D010042 Ouabain results in decreased secretion of REN protein PMID:6093556
12158997 REN renin gene CHEBI:472805 ouabain multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010042 Vanadates inhibits the reaction [Ouabain results in decreased secretion of REN protein] PMID:6093556
12158997 REN renin gene CHEBI:4784 enalapril increases activity EXP E RGD:6480464 20191114 CTD MESH:D004656 Enalapril results in increased activity of REN protein PMID:12019275
12158997 REN renin gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 [Enalapril co-treated with FR 173657] results in increased activity of REN protein PMID:12019275
12158997 REN renin gene CHEBI:64317 isoprenaline increases activity EXP E RGD:6480464 20191114 CTD MESH:D007545 Isoproterenol results in increased activity of REN protein PMID:6103674
12158997 REN renin gene CHEBI:64317 isoprenaline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007545 Atenolol inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Pindolol inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of REN protein]; xibenolol inhibits the reaction [Isoproterenol results in increased activity of REN protein] PMID:6103674
12158997 REN renin gene CHEBI:6541 losartan increases expression EXP E RGD:6480464 20191114 CTD MESH:D019808 Losartan results in increased expression of REN protein PMID:10483973
12158997 REN renin gene CHEBI:74125 losartan carboxylic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:C066026 losartan carboxylic acid results in increased expression of REN protein PMID:10483973
12158997 REN renin gene CHEBI:7596 nitroprusside increases activity EXP E RGD:6480464 20191114 CTD MESH:D009599 Nitroprusside results in increased activity of REN protein PMID:2434793|PMID:6399253
12158997 REN renin gene CHEBI:7983 pentobarbital increases activity EXP E RGD:6480464 20191114 CTD MESH:D010424 Pentobarbital results in increased activity of REN protein PMID:6348358
12158997 REN renin gene CHEBI:8093 phenylephrine increases secretion EXP E RGD:6480464 20191114 CTD MESH:D010656 Phenylephrine results in increased secretion of REN protein PMID:6347479
12158997 REN renin gene CHEBI:8214 pindolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010869 Pindolol inhibits the reaction [Isoproterenol results in increased activity of REN protein] PMID:6103674
12158997 REN renin gene CHEBI:8499 propranolol decreases activity EXP E RGD:6480464 20191114 CTD MESH:D011433 Propranolol results in decreased activity of REN protein PMID:2566282
12158997 REN renin gene CHEBI:8499 propranolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011433 Propranolol inhibits the reaction [Isoproterenol results in increased activity of REN protein] PMID:6103674
12158997 REN renin gene CHEBI:8862 Rilmenidine decreases activity EXP E RGD:6480464 20191114 CTD MESH:C032302 Rilmenidine results in decreased activity of REN protein PMID:2866274
12159064 SQOR sulfide quinone oxidoreductase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SQOR mRNA PMID:38866337
12159897 CIDEC cell death inducing DFFA like effector c gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CIDEC mRNA PMID:38866337
12160227 RPS6KB1 ribosomal protein S6 kinase B1 gene CHEBI:9753 troglitazone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C057693 Troglitazone results in decreased activity of and results in decreased phosphorylation of RPS6KB1 protein PMID:16825603
12160509 FBXW2 F-box and WD repeat domain containing 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FBXW2 mRNA PMID:38866337
12160905 PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PRKAG2 mRNA PMID:38866337
12161695 CCL4 chemokine (C-C motif) ligand 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CCL4 mRNA PMID:38866337
12162018 NOS2 nitric oxide synthase 2 gene CHEBI:17883 hydrogen chloride increases activity EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in increased activity of NOS2 protein PMID:14621274
12162071 MOB3B MOB kinase activator 3B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MOB3B mRNA PMID:38866337
12162165 NR4A2 nuclear receptor subfamily 4 group A member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NR4A2 mRNA PMID:38866337
12162819 VPS16 VPS16 core subunit of CORVET and HOPS complexes gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS16 mRNA PMID:27255383
12163923 RMND5A required for meiotic nuclear division 5 homolog A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RMND5A mRNA PMID:38866337
12164361 SIX4 SIX homeobox 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SIX4 mRNA PMID:38866337
12164524 PPP4R3A protein phosphatase 4 regulatory subunit 3A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPP4R3A mRNA PMID:38866337
12164689 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of NDUFS1 mRNA PMID:22747577
12164984 SPP1 secreted phosphoprotein 1 gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20210608 CTD MESH:D005839 Gentamicins results in increased expression of SPP1 protein PMID:33290828
12165190 IRAK2 interleukin 1 receptor associated kinase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IRAK2 mRNA PMID:38866337
12165774 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ENPP5 mRNA PMID:38866337
12166102 OGA O-GlcNAcase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of OGA mRNA PMID:38866337
12166192 ZNF622 zinc finger protein 622 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZNF622 mRNA PMID:38866337
12166457 FTCD formimidoyltransferase cyclodeaminase gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of FTCD protein PMID:19952500
12166544 APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of APEX2 mRNA PMID:38866337
12166880 DIO1 iodothyronine deiodinase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DIO1 mRNA PMID:38866337
12166903 SLMAP sarcolemma associated protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SLMAP mRNA PMID:38866337
12167208 KCNJ15 potassium inwardly rectifying channel subfamily J member 15 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KCNJ15 mRNA PMID:38866337
12167304 NADK NAD kinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NADK mRNA PMID:38866337
12167375 ALAS2 5'-aminolevulinate synthase 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ALAS2 mRNA PMID:22747577
12167898 SELENBP1 selenium binding protein 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of SELENBP1 protein PMID:19952500
12167898 SELENBP1 selenium binding protein 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of SELENBP1 protein PMID:22747577
12167898 SELENBP1 selenium binding protein 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of SELENBP1 protein PMID:19952500
12169167 DDIT3 DNA damage inducible transcript 3 gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of DDIT3 mRNA PMID:24582689
12169455 UTP20 UTP20 small subunit processome component gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of UTP20 mRNA PMID:38866337
12169872 CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 gene CHEBI:6931 midazolam affects metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D008874 CYP3A4 protein affects the metabolism of Midazolam; CYP3A5 protein affects the metabolism of Midazolam PMID:15801540
12169872 CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of CYP3A4 mRNA PMID:19952500
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:15342 acenaphthoquinone increases reduction EXP E RGD:6480464 20191114 CTD MESH:C023722 DHRS4 protein results in increased reduction of acenaphthenequinone PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:16243 quercetin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D011794 Quercetin results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:16325 lithocholic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D008095 Lithocholic Acid results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:17639 3-oxo-5beta-cholanic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:C046230 3-oxocholan-24-oic acid results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:18280 phenylglyoxylic acid increases reduction EXP E RGD:6480464 20191114 CTD MESH:C012482 DHRS4 protein results in increased reduction of phenylglyoxylic acid PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:27539 isatin increases reduction EXP E RGD:6480464 20191114 CTD MESH:D007510 DHRS4 protein results in increased reduction of Isatin PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:28088 genistein decreases activity EXP E RGD:6480464 20191114 CTD MESH:D019833 Genistein results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:28499 kaempferol decreases activity EXP E RGD:6480464 20191114 CTD MESH:C006552 kaempferol results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:28869 menadione increases reduction EXP E RGD:6480464 20191114 CTD MESH:D024483 DHRS4 protein results in increased reduction of Vitamin K 3 PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:28875 tetradecanoic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D019814 Myristic Acid results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:34166 16-Ketoestrone increases reduction EXP E RGD:6480464 20191114 CTD MESH:C002591 DHRS4 protein results in increased reduction of 16-ketoestrone PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:36237 cholanic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:C007036 cholanic acid results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:36812 valerophenone increases reduction EXP E RGD:6480464 20191114 CTD MESH:C547345 DHRS4 protein results in increased reduction of valerophenone PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:37454 9,10-phenanthroquinone increases reduction EXP E RGD:6480464 20191114 CTD MESH:C005399 DHRS4 protein results in increased reduction of 9,10-phenanthrenequinone PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:39867 valproic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D014635 Valproic Acid results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:42638 flufenamic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D005439 Flufenamic Acid results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:52774 pentane-2,3-dione increases reduction EXP E RGD:6480464 20191114 CTD MESH:C013186 DHRS4 protein results in increased reduction of 2,3-pentanedione PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of DHRS4 mRNA PMID:22747577
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:63836 bromosulfophthalein decreases activity EXP E RGD:6480464 20191114 CTD MESH:D013448 Sulfobromophthalein results in decreased activity of DHRS4 protein PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:78273 9-cis-retinal increases reduction EXP E RGD:6480464 20191114 CTD MESH:C031390 DHRS4 protein results in increased reduction of 9-cis-retinal PMID:17827741
12169889 DHRS4 hydrogenase/reductase 4 gene CHEBI:87583 hexane-2,3-dione increases reduction EXP E RGD:6480464 20191114 CTD MESH:C043231 DHRS4 protein results in increased reduction of 2,3-hexanedione PMID:17827741
12169940 AK1 adenylate kinase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AK1 mRNA PMID:38866337
12170359 CNR2 cannabinoid receptor 2 gene CHEBI:135574 nabilone affects binding EXP E RGD:6480464 20191114 CTD MESH:C011941 nabilone binds to CNR2 protein PMID:21871882
12170359 CNR2 cannabinoid receptor 2 gene CHEBI:146245 SR 144528 multiple interactions EXP E RGD:6480464 20200407 CTD MESH:C110630 SR 144528 binds to and results in decreased activity of CNR2 protein PMID:21871882
12170359 CNR2 cannabinoid receptor 2 gene CHEBI:73295 WIN 55212-2 affects binding EXP E RGD:6480464 20191114 CTD MESH:C070417 (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to CNR2 protein PMID:21871882
12170679 SYNE4 spectrin repeat containing nuclear envelope family member 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SYNE4 mRNA PMID:38866337
12170999 USP13 ubiquitin specific peptidase 13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of USP13 mRNA PMID:38866337
12171068 PPP1R3B protein phosphatase 1 regulatory subunit 3B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PPP1R3B mRNA PMID:38866337
12171468 CYP4A37 cytochrome P450 4A37 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20250715 CTD MESH:D002994 Clofibrate results in increased expression of CYP4A11 mRNA PMID:19952500
12171468 CYP4A37 cytochrome P450 4A37 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20250715 CTD MESH:D010634 Phenobarbital results in decreased expression of CYP4A11 mRNA PMID:19952500
12171700 ALDH1L2 aldehyde dehydrogenase 1 family member L2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ALDH1L2 mRNA PMID:38866337
12171830 PPA1 inorganic pyrophosphatase 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of PPA1 protein PMID:22747577
12171877 GPR85 G protein-coupled receptor 85 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GPR85 mRNA PMID:38866337
12172050 WDFY1 WD repeat and FYVE domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of WDFY1 mRNA PMID:38866337
12172546 TXNIP thioredoxin interacting protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TXNIP mRNA PMID:38866337
12172701 BTG1 BTG anti-proliferation factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BTG1 mRNA PMID:38866337
12173937 GSTO1 glutathione S-transferase omega 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of GSTO1 mRNA PMID:19952500
12173937 GSTO1 glutathione S-transferase omega 1 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of GSTO1 mRNA PMID:19952500
12174068 TUFT1 tuftelin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TUFT1 mRNA PMID:38866337
12174419 VXN vexin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of VXN mRNA PMID:38866337
12174429 GAR1 GAR1 ribonucleoprotein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GAR1 mRNA PMID:38866337
12174507 HOXD8 homeobox D8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HOXD8 mRNA PMID:38866337
12175281 MC1R melanocortin 1 receptor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MC1R mRNA PMID:38866337
12175428 AGBL4 AGBL carboxypeptidase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AGBL4 mRNA PMID:38866337
12175766 NTRK1 neurotrophic receptor tyrosine kinase 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of NTRK1 mRNA PMID:22747577
12175808 MIR152 microRNA mir-152 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR152 PMID:40036580
12175992 NRP1 neuropilin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NRP1 mRNA PMID:38866337
12176018 MYOZ1 myozenin 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of MYOZ1 mRNA PMID:22747577
12176711 CLU clusterin gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20191114 CTD MESH:D005839 Gentamicins results in increased expression of CLU mRNA; Gentamicins results in increased expression of CLU protein PMID:25034533|PMID:33290828
12176711 CLU clusterin gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of CLU protein PMID:40036580
12177957 RHOU ras homolog family member U gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RHOU mRNA PMID:38866337
12177980 PCK1 phosphoenolpyruvate carboxykinase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PCK1 mRNA PMID:38866337
12178044 AHR aryl hydrocarbon receptor gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013749 [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Tetrachlorodibenzodioxin; [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Tetrachlorodibenzodioxin; [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12178044 AHR aryl hydrocarbon receptor gene CHEBI:28909 iprodione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C033148 [iprodione binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12178044 AHR aryl hydrocarbon receptor gene CHEBI:32114 salicylamide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C031060 [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to prochloraz; [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Tetrachlorodibenzodioxin PMID:24389113
12178044 AHR aryl hydrocarbon receptor gene CHEBI:63933 Aroclor 1254 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020111 [Chlorodiphenyl (54% Chlorine) binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12178044 AHR aryl hydrocarbon receptor gene CHEBI:8434 prochloraz multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C045362 [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to prochloraz; [prochloraz binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein; [salicylamide binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to prochloraz PMID:24389113
12179378 HTATSF1 HIV-1 Tat specific factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HTATSF1 mRNA PMID:38866337
12179504 PARP15 poly(ADP-ribose) polymerase family member 15 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PARP15 mRNA PMID:38866337
12179672 CTHRC1 collagen triple helix repeat containing 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CTHRC1 mRNA PMID:38866337
12179802 CYCS cytochrome c, somatic gene CHEBI:192461 toosendanin multiple interactions EXP E RGD:6480464 20240604 CTD MESH:C036454 toosendanin results in increased expression of and affects the localization of CYCS protein PMID:36809669
12179821 MYOM1 myomesin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MYOM1 mRNA PMID:38866337
12180515 CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of CYP2A13 mRNA PMID:19952500
12180515 CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of CYP2A13 mRNA PMID:19952500
12181438 ASCC1 activating signal cointegrator 1 complex subunit 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ASCC1 mRNA PMID:22747577
12182321 CLDN1 claudin 1 gene CHEBI:15367 all-trans-retinoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased expression of CLDN1 mRNA; Tretinoin results in increased expression of CLDN1 protein PMID:17035595
12182321 CLDN1 claudin 1 gene CHEBI:15367 all-trans-retinoic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014212 CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN1 mRNA] PMID:17035595
12182321 CLDN1 claudin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CLDN1 mRNA PMID:38866337
12182644 LOC475707 GPN-loop GTPase 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of GPN1 mRNA PMID:22747577
12183043 BMPR1B bone morphogenetic protein receptor type 1B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of BMPR1B mRNA PMID:38866337
12183933 FRMD3 FERM domain containing 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FRMD3 mRNA PMID:38866337
12184043 CYP2C41 cytochrome P450 2C41 gene CHEBI:17578 toluene affects metabolic processing EXP E RGD:6480464 20231128 CTD MESH:D014050 CYP2C11 protein affects the metabolism of Toluene PMID:8592870
12184043 CYP2C41 cytochrome P450 2C41 gene CHEBI:17847 p-cresol affects metabolic processing EXP E RGD:6480464 20231128 CTD MESH:C032538 CYP2C11 protein affects the metabolism of 4-cresol PMID:8592870
12184043 CYP2C41 cytochrome P450 2C41 gene CHEBI:17987 benzyl alcohol affects metabolic processing EXP E RGD:6480464 20231128 CTD MESH:D019905 CYP2C11 protein affects the metabolism of Benzyl Alcohol PMID:8592870
12184043 CYP2C41 cytochrome P450 2C41 gene CHEBI:47381 diclofenac affects metabolic processing EXP E RGD:6480464 20220412 CTD MESH:D004008 CYP2C9 protein affects the metabolism of Diclofenac PMID:15801540
12184327 RNF144B ring finger protein 144B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RNF144B mRNA PMID:38866337
12184537 TCTN3 tectonic family member 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TCTN3 mRNA PMID:38866337
12184558 ACSM3 acyl-CoA synthetase medium chain family member 3 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ACSM3 mRNA PMID:22747577
12185148 SEC24D SEC24 homolog D, COPII coat complex component gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SEC24D mRNA PMID:27255383
12185184 ATP6V0D1 ATPase H+ transporting V0 subunit d1 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of ATP6V0D1 protein PMID:32991862
12185421 ACHE acetylcholinesterase gene CHEBI:136185 VX nerve agent decreases activity EXP E RGD:6480464 20191114 CTD MESH:C009680 VX-agent results in decreased activity of ACHE protein PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:136185 VX nerve agent multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C009680 [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX-agent results in decreased activity of ACHE protein] PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:16684 atropine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001285 [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX-agent results in decreased activity of ACHE protein] PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:34690 dichlorvos decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004006 Dichlorvos results in decreased activity of ACHE protein PMID:3627083|PMID:89824
12185421 ACHE acetylcholinesterase gene CHEBI:75701 sarin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D012524 Sarin results in decreased activity of ACHE protein PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:75701 sarin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012524 [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein] PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:78734 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001285 [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX-agent results in decreased activity of ACHE protein] PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:9195 Soman decreases activity EXP E RGD:6480464 20191114 CTD MESH:D012999 Soman results in decreased activity of ACHE protein PMID:16915560
12185421 ACHE acetylcholinesterase gene CHEBI:9195 Soman multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012999 [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein] PMID:16915560
12185507 HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HSD17B7 mRNA PMID:38866337
12185593 TEAD4 TEA domain transcription factor 4 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TEAD4 mRNA PMID:22747577
12187213 SLC2A9 solute carrier family 2 member 9 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases transport EXP E RGD:6480464 20191114 CTD MESH:D014527 SLC2A9 protein results in increased transport of Uric Acid PMID:18989453
12187275 CASK calcium/calmodulin dependent serine protein kinase gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of CASK mRNA PMID:27255383
12187382 MDH2 malate dehydrogenase 2 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of MDH2 protein PMID:32991862
12187382 MDH2 malate dehydrogenase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MDH2 mRNA PMID:38866337
12187750 HVCN1 hydrogen voltage gated channel 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HVCN1 mRNA PMID:38866337
12187832 ACE angiotensin I converting enzyme gene CHEBI:177391 Ceronapril decreases activity EXP E RGD:6480464 20210907 CTD MESH:C054518 ceronapril results in decreased activity of ACE protein PMID:1812274
12188259 PCDH20 protocadherin 20 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PCDH20 mRNA PMID:38866337
12188393 GLB1L galactosidase beta 1 like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GLB1L mRNA PMID:38866337
12188501 NOX4 NADPH oxidase 4 gene CHEBI:32020 pitavastatin decreases expression EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in decreased expression of NOX4 mRNA PMID:15502390
12188501 NOX4 NADPH oxidase 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NOX4 mRNA PMID:38866337
12188501 NOX4 NADPH oxidase 4 gene CHEBI:71260 pitavastatin(1-) decreases expression EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in decreased expression of NOX4 mRNA PMID:15502390
12188532 ADRA2A adrenoceptor alpha 2A gene CHEBI:3757 clonidine (imino form) increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D003000 ADRA2A protein results in increased susceptibility to Clonidine PMID:16814767
12188532 ADRA2A adrenoceptor alpha 2A gene CHEBI:3757 clonidine (imino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine binds to and results in increased activity of ADRA2A protein PMID:16814767
12188532 ADRA2A adrenoceptor alpha 2A gene CHEBI:46631 clonidine increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D003000 ADRA2A protein results in increased susceptibility to Clonidine PMID:16814767
12188532 ADRA2A adrenoceptor alpha 2A gene CHEBI:46631 clonidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine binds to and results in increased activity of ADRA2A protein PMID:16814767
12188532 ADRA2A adrenoceptor alpha 2A gene CHEBI:46632 clonidine (amino form) increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D003000 ADRA2A protein results in increased susceptibility to Clonidine PMID:16814767
12188532 ADRA2A adrenoceptor alpha 2A gene CHEBI:46632 clonidine (amino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine binds to and results in increased activity of ADRA2A protein PMID:16814767
12188586 CIPC CLOCK interacting pacemaker gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CIPC mRNA PMID:38866337
12188655 RNF169 ring finger protein 169 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RNF169 mRNA PMID:38866337
12188915 ACTR2 actin related protein 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ACTR2 protein PMID:22747577
12189900 PDIA3 protein disulfide isomerase family A member 3 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PDIA3 protein PMID:22747577
12189900 PDIA3 protein disulfide isomerase family A member 3 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of PDIA3 protein PMID:19952500
12190112 KCNJ2 potassium inwardly rectifying channel subfamily J member 2 gene CHEBI:17347 testosterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D013739 Testosterone results in increased expression of KCNJ2 protein PMID:17054656
12190635 TAF4B TATA-box binding protein associated factor 4b gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TAF4B mRNA PMID:38866337
12190654 SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SMCHD1 mRNA PMID:38866337
12190768 RAB31 RAB31, member RAS oncogene family gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of RAB31 mRNA PMID:27255383
12190790 WT1 WT1 transcription factor gene CHEBI:16480 nitric oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009569 [Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of WT1 mRNA PMID:21443142
12190790 WT1 WT1 transcription factor gene CHEBI:7596 nitroprusside multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009599 [Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of WT1 mRNA PMID:21443142
12191266 NFATC2IP nuclear factor of activated T cells 2 interacting protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NFATC2IP mRNA PMID:38866337
12191521 TAOK1 TAO kinase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TAOK1 mRNA PMID:38866337
12191892 PLD4 phospholipase D family member 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PLD4 mRNA PMID:38866337
12191929 NIPAL3 NIPA like domain containing 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NIPAL3 mRNA PMID:38866337
12192059 IL1B interleukin 1 beta gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20220405 CTD MESH:D008070 Lipopolysaccharides results in increased expression of IL1B mRNA PMID:32899721
12192059 IL1B interleukin 1 beta gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20220405 CTD MESH:D008070 arsenite affects the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]] PMID:32899721
12192059 IL1B interleukin 1 beta gene CHEBI:29866 arsenite(3-) multiple interactions EXP E RGD:6480464 20220405 CTD MESH:C015001 arsenite affects the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]] PMID:32899721
12192059 IL1B interleukin 1 beta gene CHEBI:44445 nimesulide decreases expression EXP E RGD:6480464 20191114 CTD MESH:C012655 nimesulide results in decreased expression of IL1B mRNA PMID:19638440
12192059 IL1B interleukin 1 beta gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of IL1B mRNA; ochratoxin A results in increased expression of IL1B protein PMID:33543323
12192059 IL1B interleukin 1 beta gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of IL1B mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of IL1B mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of IL1B mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of IL1B protein] PMID:33543323
12192158 VPS33B VPS33B late endosome and lysosome associated gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS33B mRNA PMID:27255383
12192371 ALPI alkaline phosphatase, intestinal gene CHEBI:17263 estrone increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:D004970 ALPI protein results in increased chemical synthesis of Estrone PMID:1495895
12192371 ALPI alkaline phosphatase, intestinal gene CHEBI:17440 4-nitrophenyl phosphate increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:C008644 ALPI protein results in increased chemical synthesis of nitrophenylphosphate PMID:1495895
12192371 ALPI alkaline phosphatase, intestinal gene CHEBI:27632 acetophenone increases chemical synthesis EXP E RGD:6480464 20191114 CTD MESH:C038699 ALPI protein results in increased chemical synthesis of acetophenone PMID:1495895
12193001 HMGA2 high mobility group AT-hook 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HMGA2 mRNA PMID:38866337
12193223 AHCYL2 adenosylhomocysteinase like 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AHCYL2 mRNA PMID:38866337
12193986 STRIT1 small transmembrane regulator of ion transport 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of STRIT1 mRNA PMID:38866337
12194006 MIR26A-1 microRNA mir-26a-1 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR26A-1 PMID:40036580
12194335 MGMT O-6-methylguanine-DNA methyltransferase gene CHEBI:3423 carmustine decreases response to substance EXP E RGD:6480464 20191114 CTD MESH:D002330 MGMT protein mutant form results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine PMID:15053863
12194335 MGMT O-6-methylguanine-DNA methyltransferase gene CHEBI:3423 carmustine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002330 MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine] PMID:14617759
12194478 GAP43 growth associated protein 43 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GAP43 mRNA PMID:38866337
12194613 PMEL premelanosome protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PMEL mRNA PMID:38866337
12194917 RUNDC1 RUN domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RUNDC1 mRNA PMID:38866337
12194926 TAF1 TATA-box binding protein associated factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TAF1 mRNA PMID:38866337
12195176 MIR30C-1 microRNA mir-30c-1 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR30C-1 PMID:40036580
12195484 DNAL4 dynein axonemal light chain 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DNAL4 mRNA PMID:38866337
12195592 SAE1 SUMO1 activating enzyme subunit 1 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of SAE1 protein PMID:32991862
12195612 EBPL EBP like gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of EBPL mRNA PMID:22747577
12195783 RAP2C RAP2C, member of RAS oncogene family gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RAP2C mRNA PMID:38866337
12196334 STX16 syntaxin 16 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of STX16 mRNA PMID:22747577
12196470 JAZF1 JAZF zinc finger 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of JAZF1 mRNA PMID:38866337
12197397 ZNF81 zinc finger protein 81 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ZNF81 mRNA PMID:38866337
12197462 CYP2U1 cytochrome P450 family 2 subfamily U member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CYP2U1 mRNA PMID:38866337
12197582 LIN7A lin-7 homolog A, crumbs cell polarity complex component gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LIN7A mRNA PMID:38866337
12197694 NEK2 NIMA related kinase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NEK2 mRNA PMID:38866337
12197733 ARF4 ADP ribosylation factor 4 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of ARF4 mRNA PMID:27255383
12197785 RYR2 ryanodine receptor 2 gene CHEBI:3441 carvedilol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased oxidation of and results in increased stability of RYR2 protein PMID:17448375
12198058 CSNK1G1 casein kinase 1 gamma 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CSNK1G1 mRNA PMID:38866337
12198177 CPEB4 cytoplasmic polyadenylation element binding protein 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CPEB4 mRNA PMID:38866337
12198262 ANKRD50 ankyrin repeat domain containing 50 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ANKRD50 mRNA PMID:38866337
12198974 NAPG NSF attachment protein gamma gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of NAPG mRNA PMID:22747577
12199021 APP amyloid beta precursor protein gene CHEBI:28694 copper atom increases expression EXP E RGD:6480464 20191114 CTD MESH:D003300 Copper results in increased expression of APP protein PMID:16886094
12199021 APP amyloid beta precursor protein gene CHEBI:30052 copper(0) increases expression EXP E RGD:6480464 20191114 CTD MESH:D003300 Copper results in increased expression of APP protein PMID:16886094
12199089 LOC474850 heat shock 70 kDa protein 1-like gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of HSPA1L mRNA PMID:22747577
12199478 TMC7 transmembrane channel like 7 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMC7 mRNA PMID:38866337
12199883 PSMD9 proteasome 26S subunit, non-ATPase 9 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of PSMD9 mRNA PMID:22747577
12201020 CPNE1 copine 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CPNE1 mRNA PMID:22747577
12201114 CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CTR9 mRNA PMID:38866337
12201171 FGFR2 fibroblast growth factor receptor 2 gene CHEBI:17883 hydrogen chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in increased expression of FGFR2 mRNA PMID:15883737
12201592 TTC21A tetratricopeptide repeat domain 21A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TTC21A mRNA PMID:38866337
12202061 USP18 ubiquitin specific peptidase 18 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of USP18 mRNA PMID:38866337
12203515 TMEM108 transmembrane protein 108 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TMEM108 mRNA PMID:22747577
12203725 DLA-DOB major histocompatibility complex, class II, DO beta gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DLA-DOB mRNA PMID:38866337
12203958 MGST1 microsomal glutathione S-transferase 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of MGST1 mRNA PMID:19952500
12203958 MGST1 microsomal glutathione S-transferase 1 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of MGST1 mRNA PMID:19952500
12204155 SPTBN1 spectrin beta, non-erythrocytic 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SPTBN1 mRNA PMID:27255383
12204443 LGALS12 galectin 12 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LGALS12 mRNA PMID:38866337
12204595 KRT16 keratin 16 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KRT16 mRNA PMID:38866337
12205088 CRYBG3 crystallin beta-gamma domain containing 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CRYBG3 mRNA PMID:38866337
12205481 FAH fumarylacetoacetate hydrolase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FAH mRNA PMID:38866337
12205499 PIF1 PIF1 5'-to-3' DNA helicase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PIF1 mRNA PMID:38866337
12205516 ITGA6 integrin subunit alpha 6 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ITGA6 mRNA PMID:22747577
12205685 ATP5F1B ATP synthase F1 subunit beta gene CHEBI:17883 hydrogen chloride decreases expression EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in decreased expression of ATP5F1B mRNA PMID:15883737
12205685 ATP5F1B ATP synthase F1 subunit beta gene CHEBI:17883 hydrogen chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006851 [Hydrochloric Acid co-treated with Bile Acids and Salts] results in decreased expression of ATP5F1B mRNA PMID:15883737
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:60427 dioleoyl phosphatidic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:C037657 dioleoylphosphatidic acid results in increased activity of PLCG1 protein PMID:2001791
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:62085 dimyristoyl phosphatidic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:C025602 dimyristoylphosphatidic acid results in increased activity of PLCG1 protein PMID:2001791
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:72999 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine decreases activity EXP E RGD:6480464 20191114 CTD MESH:D015060 1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein PMID:2001791
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:72999 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015060 dipalmitoylphosphatidic acid inhibits the reaction [1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein] PMID:2001791
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:78105 dihexadecanoyl phosphatidic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:C031599 dipalmitoylphosphatidic acid results in increased activity of PLCG1 protein PMID:2001791
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:78105 dihexadecanoyl phosphatidic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C031599 dipalmitoylphosphatidic acid inhibits the reaction [1,2-Dipalmitoylphosphatidylcholine results in decreased activity of PLCG1 protein] PMID:2001791
12206121 PLCG1 phospholipase C gamma 1 gene CHEBI:84165 1-stearoyl-2-arachidonoylphosphatidic acid increases activity EXP E RGD:6480464 20191114 CTD MESH:C060203 1-stearoyl-2-arachidonoylphosphatidic acid results in increased activity of PLCG1 protein PMID:2001791
12206702 ANP32E acidic nuclear phosphoprotein 32 family member E gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ANP32E mRNA PMID:22747577
12206766 TNNT2 troponin T2, cardiac type gene CHEBI:28748 doxorubicin affects expression EXP E RGD:6480464 20191114 CTD MESH:D004317 Doxorubicin affects the expression of TNNT2 protein PMID:12322705
12206884 COPB1 COPI coat complex subunit beta 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of COPB1 mRNA PMID:27255383
12206910 DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of DNAJC3 protein PMID:32991862
12206983 ENO1 enolase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ENO1 mRNA PMID:38866337
12207057 HIF1A hypoxia inducible factor 1 subunit alpha gene CHEBI:34159 15-deoxy-Delta(12,14)-prostaglandin J2 increases expression EXP E RGD:6480464 20191114 CTD MESH:C097240 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein PMID:17658243
12207336 SCD stearoyl-CoA desaturase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SCD mRNA PMID:38866337
12207336 SCD stearoyl-CoA desaturase gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of SCD mRNA PMID:22747577
12207969 ADPRH ADP-ribosylarginine hydrolase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ADPRH mRNA PMID:22747577
12208021 PKDREJ polycystin family receptor for egg jelly gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PKDREJ mRNA PMID:38866337
12208058 GSTK1 glutathione S-transferase kappa 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of GSTK1 mRNA PMID:19952500
12208107 HEATR1 HEAT repeat containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HEATR1 mRNA PMID:38866337
12208319 LOC486353 SEC14-like protein 4 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of SEC14L4 protein PMID:19952500
12208650 XRCC3 X-ray repair cross complementing 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of XRCC3 mRNA PMID:38866337
12208810 REPS2 RALBP1 associated Eps domain containing 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of REPS2 mRNA PMID:38866337
12208860 SAP30L SAP30 like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SAP30L mRNA PMID:38866337
12209006 IMMT inner membrane mitochondrial protein gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of IMMT protein PMID:32991862
12209509 GPT glutamic--pyruvic transaminase gene CHEBI:9728 trimethaphan increases expression EXP E RGD:6480464 20191114 CTD MESH:D014294 Trimethaphan results in increased expression of GPT protein PMID:6848019
12209590 MAP10 microtubule associated protein 10 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAP10 mRNA PMID:38866337
12209713 NSG1 neuronal vesicle trafficking associated 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of NSG1 mRNA PMID:22747577
12210134 SCN10A sodium voltage-gated channel alpha subunit 10 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SCN10A mRNA PMID:27255383
12210423 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of REV3L mRNA PMID:38866337
12210549 F2RL1 F2R like trypsin receptor 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of F2RL1 mRNA PMID:38866337
12210611 LCN2 lipocalin 2 gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20191114 CTD MESH:D005839 Gentamicins results in increased expression of LCN2 mRNA; Gentamicins results in increased expression of LCN2 protein PMID:25034533|PMID:33290828
12211560 SLC40A1 solute carrier family 40 member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC40A1 mRNA PMID:38866337
12211880 KCNIP1 potassium voltage-gated channel interacting protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KCNIP1 mRNA PMID:38866337
12212152 EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EIF2B5 mRNA PMID:38866337
12212351 AMMECR1 AMMECR nuclear protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AMMECR1 mRNA PMID:38866337
12212542 TSHB thyroid stimulating hormone subunit beta gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TSHB mRNA PMID:22747577
12212878 VTI1B vesicle transport through interaction with t-SNAREs 1B gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VTI1B mRNA PMID:27255383
12213188 GABRQ gamma-aminobutyric acid type A receptor subunit theta gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GABRQ mRNA] PMID:25419811
12213188 GABRQ gamma-aminobutyric acid type A receptor subunit theta gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GABRQ mRNA] PMID:25419811
12213188 GABRQ gamma-aminobutyric acid type A receptor subunit theta gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GABRQ mRNA] PMID:25419811
12213188 GABRQ gamma-aminobutyric acid type A receptor subunit theta gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GABRQ mRNA] PMID:25419811
12213368 CDKN1A cyclin dependent kinase inhibitor 1A gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CDKN1A mRNA PMID:22747577
12213379 AGA aspartylglucosaminidase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of AGA mRNA PMID:22747577
12213672 CLTCL1 clathrin heavy chain like 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of CLTCL1 mRNA PMID:27255383
12213926 SIRT1 sirtuin 1 gene CHEBI:17154 nicotinamide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D009536 Niacinamide results in decreased expression of SIRT1 protein PMID:22539994
12213926 SIRT1 sirtuin 1 gene CHEBI:17154 nicotinamide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009536 Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]; Resveratrol inhibits the reaction [Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]]; Resveratrol inhibits the reaction [Niacinamide results in decreased expression of SIRT1 protein] PMID:22539994
12213926 SIRT1 sirtuin 1 gene CHEBI:27881 resveratrol increases activity EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in increased activity of SIRT1 protein PMID:22539994
12213926 SIRT1 sirtuin 1 gene CHEBI:27881 resveratrol increases expression EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol results in increased expression of SIRT1 protein PMID:21239502|PMID:22539994
12213926 SIRT1 sirtuin 1 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [[Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] which results in decreased activity of EP300 protein] which results in decreased acetylation of RELA protein; [Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] inhibits the reaction [TNFSF11 protein results in increased acetylation of and results in increased activity of RELA protein]; [Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] which results in decreased activity of EP300 protein; [Resveratrol results in increased activity of SIRT1 protein] promotes the reaction [SIRT1 protein binds to RUNX2 protein]; Resveratrol inhibits the reaction [Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]]; Resveratrol inhibits the reaction [Niacinamide results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in decreased expression of SIRT1 protein]; Resveratrol promotes the reaction [[SIRT1 protein binds to EP300 protein] which binds to RUNX2 protein]; Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]; Resveratrol promotes the reaction [SIRT1 protein binds to RUNX2 protein]; SIRT1 protein affects the reaction [Resveratrol results in decreased acetylation of RUNX2 protein] PMID:21239502|PMID:22539994
12215478 SELP selectin P gene CHEBI:31530 edaravone decreases expression EXP E RGD:6480464 20191114 CTD MESH:C005435 Edaravone results in decreased expression of SELP protein PMID:16041266
12215478 SELP selectin P gene CHEBI:9574 Thrombin increases expression EXP E RGD:6480464 20191114 CTD MESH:D013917 Thrombin results in increased expression of SELP PMID:21034320
12215829 GPAA1 glycosylphosphatidylinositol anchor attachment 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of GPAA1 mRNA PMID:27255383
12215924 EBF1 EBF transcription factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EBF1 mRNA PMID:38866337
12216615 ITGB1BP2 integrin subunit beta 1 binding protein 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ITGB1BP2 mRNA PMID:38866337
12217035 USP34 ubiquitin specific peptidase 34 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of USP34 mRNA PMID:38866337
12217214 PANK2 pantothenate kinase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PANK2 mRNA PMID:38866337
12217256 GEMIN5 gem nuclear organelle associated protein 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GEMIN5 mRNA PMID:38866337
12217575 IL18R1 interleukin 18 receptor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IL18R1 mRNA PMID:38866337
12217893 HOXA9 homeobox A9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HOXA9 mRNA PMID:38866337
12218474 RABEP1 rabaptin, RAB GTPase binding effector protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RABEP1 mRNA PMID:38866337
12218617 METTL1 methyltransferase 1, tRNA methylguanosine gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of METTL1 mRNA PMID:38866337
12218734 SOCS2 suppressor of cytokine signaling 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SOCS2 mRNA PMID:38866337
12219630 ANTXR2 ANTXR cell adhesion molecule 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ANTXR2 mRNA PMID:38866337
12219657 PKD2 polycystin 2, transient receptor potential cation channel gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PKD2 mRNA PMID:38866337
12220719 SLC27A6 solute carrier family 27 member 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC27A6 mRNA PMID:38866337
12221388 MOB1B MOB kinase activator 1B gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of MOB1B mRNA PMID:22747577
12221655 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of YWHAZ protein PMID:22747577
12222756 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DNAJB13 mRNA PMID:38866337
12223780 GNMT glycine N-methyltransferase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GNMT mRNA PMID:38866337
12223934 GDA guanine deaminase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GDA mRNA PMID:38866337
12224500 CYP2C18 cytochrome P450 2C21 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of CYP2C18 mRNA PMID:19952500
12224500 CYP2C18 cytochrome P450 2C21 gene CHEBI:47381 diclofenac increases hydroxylation EXP E RGD:6480464 20250715 CTD MESH:D004008 CYP2C19 protein results in increased hydroxylation of Diclofenac PMID:15677349
12224500 CYP2C18 cytochrome P450 2C21 gene CHEBI:49575 diazepam affects metabolic processing EXP E RGD:6480464 20250715 CTD MESH:D003975 CYP2C19 protein affects the metabolism of Diazepam PMID:15801540
12224599 ZCCHC9 zinc finger CCHC-type containing 9 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ZCCHC9 mRNA PMID:38866337
12224708 IGFBP3 insulin like growth factor binding protein 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IGFBP3 mRNA PMID:38866337
12224854 GSR glutathione-disulfide reductase gene CHEBI:29678 sodium arsenite decreases activity EXP E RGD:6480464 20191114 CTD MESH:C017947 sodium arsenite results in decreased activity of GSR protein PMID:18163546
12224854 GSR glutathione-disulfide reductase gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C017947 [monoisoamyl-2,3-dimercaptosuccinate co-treated with Succimer] inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; monoisoamyl-2,3-dimercaptosuccinate inhibits the reaction [sodium arsenite results in decreased activity of GSR protein] PMID:18163546
12224854 GSR glutathione-disulfide reductase gene CHEBI:63623 succimer multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004113 [monoisoamyl-2,3-dimercaptosuccinate co-treated with Succimer] inhibits the reaction [sodium arsenite results in decreased activity of GSR protein] PMID:18163546
12225279 QRFP pyroglutamylated RFamide peptide gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of QRFP mRNA PMID:38866337
12225383 RGS13 regulator of G protein signaling 13 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of RGS13 mRNA PMID:22747577
12225830 DAO D-amino acid oxidase gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of DAO mRNA] PMID:25419811
12225830 DAO D-amino acid oxidase gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of DAO mRNA] PMID:25419811
12225830 DAO D-amino acid oxidase gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of DAO mRNA] PMID:25419811
12225830 DAO D-amino acid oxidase gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of DAO mRNA] PMID:25419811
12226040 VPS54 VPS54 subunit of GARP complex gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of VPS54 mRNA PMID:27255383
12226319 SYTL1 synaptotagmin like 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SYTL1 mRNA PMID:27255383
12226779 LCNL1 lipocalin like 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LCNL1 mRNA PMID:38866337
12226995 COLEC12 collectin subfamily member 12 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of COLEC12 mRNA PMID:38866337
12227151 KIF5B kinesin family member 5B gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of KIF5B mRNA PMID:27255383
12227292 DENND5A DENN domain containing 5A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DENND5A mRNA PMID:38866337
12227863 RILPL2 Rab interacting lysosomal protein like 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RILPL2 mRNA PMID:38866337
12227974 ZNF556 zinc finger protein 556 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZNF556 mRNA PMID:38866337
12228288 MAPK14 mitogen-activated protein kinase 14 gene CHEBI:15355 acetylcholine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000109 Acetylcholine results in increased phosphorylation of and results in increased activity of MAPK14 protein PMID:9688607
12228338 CCT2 chaperonin containing TCP1 subunit 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of CCT2 protein PMID:22747577
12228377 UROC1 urocanate hydratase 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of UROC1 protein PMID:19952500
12228377 UROC1 urocanate hydratase 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of UROC1 protein PMID:19952500
12228880 KAZALD1 Kazal type serine peptidase inhibitor domain 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KAZALD1 mRNA PMID:38866337
12228928 SCAMP3 secretory carrier membrane protein 3 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of SCAMP3 mRNA PMID:27255383
12228997 LBH LBH regulator of WNT signaling pathway gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LBH mRNA PMID:38866337
12229486 CPQ carboxypeptidase Q gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CPQ mRNA PMID:38866337
12230130 RAB11A RAB11A, member RAS oncogene family gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of RAB11A protein PMID:32991862
12230139 PTHLH parathyroid hormone like hormone gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PTHLH mRNA PMID:38866337
12230450 KRT1 keratin 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of KRT1 protein PMID:19952500
12230481 PSMB9 proteasome 20S subunit beta 9 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PSMB9 mRNA PMID:22747577
12230682 PJA1 praja ring finger ubiquitin ligase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PJA1 mRNA PMID:38866337
12230964 CYP27A1 cytochrome P450 family 27 subfamily A member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CYP27A1 mRNA PMID:38866337
12230976 NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NAA10 mRNA PMID:38866337
12230991 PPP1R14A protein phosphatase 1 regulatory inhibitor subunit 14A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PPP1R14A mRNA PMID:38866337
12231483 EPHX2 epoxide hydrolase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EPHX2 mRNA PMID:38866337
12231506 SLC38A1 solute carrier family 38 member 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SLC38A1 mRNA PMID:38866337
12231665 STAT2 signal transducer and activator of transcription 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of STAT2 mRNA PMID:38866337
12231866 KPNA6 karyopherin subunit alpha 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KPNA6 mRNA PMID:38866337
12232056 CRABP2 cellular retinoic acid binding protein 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CRABP2 mRNA PMID:38866337
12232174 RBM11 RNA binding motif protein 11 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RBM11 mRNA PMID:38866337
12232587 GAPVD1 GTPase activating protein and VPS9 domains 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GAPVD1 mRNA PMID:38866337
12232905 BATF3 basic leucine zipper ATF-like transcription factor 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of BATF3 mRNA PMID:38866337
12233153 LRRN4CL LRRN4 C-terminal like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LRRN4CL mRNA PMID:38866337
12233533 CRB3 crumbs cell polarity complex component 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CRB3 mRNA PMID:38866337
12233742 TOP2A DNA topoisomerase II alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TOP2A mRNA PMID:38866337
12233871 DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DNAJC13 mRNA PMID:38866337
12234055 NAB1 NGFI-A binding protein 1 gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 [Ranolazine co-treated with Enalapril] affects the expression of NAB1 protein PMID:18820026
12234055 NAB1 NGFI-A binding protein 1 gene CHEBI:6904 metoprolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008790 [Ranolazine co-treated with Metoprolol] affects the expression of NAB1 protein PMID:18820026
12234055 NAB1 NGFI-A binding protein 1 gene CHEBI:87681 ranolazine affects expression EXP E RGD:6480464 20191114 CTD MESH:D000069458 Ranolazine affects the expression of NAB1 protein PMID:18820026
12234055 NAB1 NGFI-A binding protein 1 gene CHEBI:87681 ranolazine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069458 [Ranolazine co-treated with Enalapril] affects the expression of NAB1 protein; [Ranolazine co-treated with Metoprolol] affects the expression of NAB1 protein PMID:18820026
12234500 KDELR2 KDEL endoplasmic reticulum protein retention receptor 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KDELR2 mRNA PMID:38866337
12235298 ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZDHHC3 mRNA PMID:38866337
12235597 CCR4 C-C motif chemokine receptor 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CCR4 mRNA PMID:38866337
12235605 SLC22A2 solute carrier family 22 member 2 gene CHEBI:3699 cimetidine decreases activity EXP E RGD:6480464 20230801 CTD MESH:D002927 Cimetidine results in decreased activity of SLC22A2 protein PMID:36669674
12235605 SLC22A2 solute carrier family 22 member 2 gene CHEBI:81781 tebuconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087114 tebuconazole results in decreased activity of SLC22A2 protein PMID:36669674
12235605 SLC22A2 solute carrier family 22 member 2 gene CHEBI:81970 penconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087058 penconazole results in decreased activity of SLC22A2 protein PMID:36669674
12235618 IL4 interleukin 4 gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA] PMID:33763461
12235618 IL4 interleukin 4 gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA] PMID:33763461
12235905 SOD2 superoxide dismutase 2 gene CHEBI:16199 urea increases expression EXP E RGD:6480464 20191114 CTD MESH:D014508 Urea results in increased expression of SOD2 protein PMID:22718889
12235905 SOD2 superoxide dismutase 2 gene CHEBI:16240 hydrogen peroxide decreases activity EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in decreased activity of SOD2 protein PMID:16682413
12235905 SOD2 superoxide dismutase 2 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Dihydrotestosterone promotes the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein] PMID:16682413
12235905 SOD2 superoxide dismutase 2 gene CHEBI:16330 17beta-hydroxy-5alpha-androstan-3-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013196 Dihydrotestosterone promotes the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein] PMID:16682413
12235905 SOD2 superoxide dismutase 2 gene CHEBI:26710 sodium chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased expression of SOD2 protein PMID:22718889
12236669 INHBA inhibin subunit beta A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of INHBA mRNA PMID:38866337
12237396 MINAR2 membrane integral NOTCH2 associated receptor 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MINAR2 mRNA PMID:38866337
12237967 MAN1A1 mannosidase alpha class 1A member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAN1A1 mRNA PMID:38866337
12239792 CYP2B6 cytochrome P450 2B11 gene CHEBI:10033 warfarin increases hydroxylation EXP E RGD:6480464 20191114 CTD MESH:D014859 CYP2B6 protein results in increased hydroxylation of Warfarin PMID:12637241
12239792 CYP2B6 cytochrome P450 2B11 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of CYP2B6 mRNA PMID:19952500
12239792 CYP2B6 cytochrome P450 2B11 gene CHEBI:4027 cyclophosphamide increases hydroxylation EXP E RGD:6480464 20191114 CTD MESH:D003520 CYP2B6 protein results in increased hydroxylation of Cyclophosphamide PMID:16546968
12239792 CYP2B6 cytochrome P450 2B11 gene CHEBI:4470 dextromethorphan increases metabolic processing EXP E RGD:6480464 20191114 CTD MESH:D003915 CYP2B6 protein results in increased metabolism of Dextromethorphan PMID:12637241
12239792 CYP2B6 cytochrome P450 2B11 gene CHEBI:6757 mephenytoin increases hydroxylation EXP E RGD:6480464 20191114 CTD MESH:D008617 CYP2B6 protein results in increased hydroxylation of Mephenytoin PMID:12637241
12239792 CYP2B6 cytochrome P450 2B11 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of CYP2B6 protein PMID:19952500
12239805 PLAA phospholipase A2 activating protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PLAA mRNA PMID:38866337
12239972 ABLIM1 actin binding LIM protein 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ABLIM1 mRNA PMID:22747577
12240290 P2RY2 purinergic receptor P2Y2 gene CHEBI:15713 UTP increases activity EXP E RGD:6480464 20191114 CTD MESH:D014544 Uridine Triphosphate results in increased activity of P2RY2 protein PMID:10604969
12240290 P2RY2 purinergic receptor P2Y2 gene CHEBI:15713 UTP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014544 [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid; [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] PMID:10604969
12240290 P2RY2 purinergic receptor P2Y2 gene CHEBI:15843 arachidonic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D016718 [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid] PMID:10604969
12240290 P2RY2 purinergic receptor P2Y2 gene CHEBI:17489 3',5'-cyclic AMP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000242 [Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] PMID:10604969
12240290 P2RY2 purinergic receptor P2Y2 gene CHEBI:34941 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C077792 pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Arachidonic Acid]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Uridine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Cyclic AMP] PMID:10604969
12240550 SNX24 sorting nexin 24 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SNX24 mRNA PMID:27255383
12240844 NVL nuclear VCP like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NVL mRNA PMID:38866337
12241493 HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HNRNPA3 mRNA PMID:38866337
12242272 CHKA choline kinase alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CHKA mRNA PMID:38866337
12242498 PGK1 phosphoglycerate kinase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PGK1 mRNA PMID:38866337
12242625 KCNJ6 potassium inwardly rectifying channel subfamily J member 6 gene CHEBI:15355 acetylcholine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000109 Acetylcholine promotes the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium] PMID:10666054
12242625 KCNJ6 potassium inwardly rectifying channel subfamily J member 6 gene CHEBI:26216 potassium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011188 [KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium; Acetylcholine promotes the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium]; Barium inhibits the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium] PMID:10666054
12242625 KCNJ6 potassium inwardly rectifying channel subfamily J member 6 gene CHEBI:32595 barium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001464 Barium inhibits the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium] PMID:10666054
12243013 FGF7 fibroblast growth factor 7 gene CHEBI:17883 hydrogen chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in increased expression of FGF7 mRNA PMID:15883737
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:15367 all-trans-retinoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased expression of NOS3 mRNA; Tretinoin results in increased expression of NOS3 protein PMID:17267746
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:32020 pitavastatin increases activity EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in increased activity of NOS3 protein PMID:15502390
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:32020 pitavastatin increases expression EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in increased expression of NOS3 mRNA PMID:15502390
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:4784 enalapril increases expression EXP E RGD:6480464 20191114 CTD MESH:D004656 Enalapril results in increased expression of NOS3 mRNA PMID:12019275
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 FR 173657 inhibits the reaction [Enalapril results in increased expression of NOS3 mRNA] PMID:12019275
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:71260 pitavastatin(1-) increases activity EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in increased activity of NOS3 protein PMID:15502390
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:71260 pitavastatin(1-) increases expression EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in increased expression of NOS3 mRNA PMID:15502390
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:78420 icariin increases activity EXP E RGD:6480464 20191114 CTD MESH:C056599 icariin results in increased activity of NOS3 protein PMID:17438405
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:9150 simvastatin decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019821 Simvastatin results in decreased expression of NOS3 mRNA PMID:11087217
12243345 NOS3 nitric oxide synthase 3 gene CHEBI:9150 simvastatin increases expression EXP E RGD:6480464 20191114 CTD MESH:D019821 Simvastatin results in increased expression of NOS3 protein PMID:11087217
12243442 ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ARFGEF2 mRNA PMID:38866337
12243930 PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PPP1R1A mRNA PMID:38866337
12244037 ZC3H6 zinc finger CCCH-type containing 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZC3H6 mRNA PMID:38866337
12244264 OCLN occludin gene CHEBI:15367 all-trans-retinoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased expression of OCLN mRNA; Tretinoin results in increased expression of OCLN protein PMID:17035595
12244264 OCLN occludin gene CHEBI:15367 all-trans-retinoic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014212 CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of OCLN mRNA] PMID:17035595
12244264 OCLN occludin gene CHEBI:35456 cadmium dichloride decreases expression EXP E RGD:6480464 20191114 CTD MESH:D019256 Cadmium Chloride results in decreased expression of OCLN protein PMID:18418844
12244289 BIRC5 baculoviral IAP repeat containing 5 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of BIRC5 mRNA PMID:22747577
12244446 EGR1 early growth response 1 gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 [Ranolazine co-treated with Enalapril] affects the expression of EGR1 protein PMID:18820026
12244446 EGR1 early growth response 1 gene CHEBI:6904 metoprolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008790 [Ranolazine co-treated with Metoprolol] affects the expression of EGR1 protein PMID:18820026
12244446 EGR1 early growth response 1 gene CHEBI:87681 ranolazine affects expression EXP E RGD:6480464 20191114 CTD MESH:D000069458 Ranolazine affects the expression of EGR1 protein PMID:18820026
12244446 EGR1 early growth response 1 gene CHEBI:87681 ranolazine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069458 [Ranolazine co-treated with Enalapril] affects the expression of EGR1 protein; [Ranolazine co-treated with Metoprolol] affects the expression of EGR1 protein PMID:18820026
12244661 AK5 adenylate kinase 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AK5 mRNA PMID:38866337
12244713 RETREG3 reticulophagy regulator family member 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RETREG3 mRNA PMID:38866337
12244740 PXMP4 peroxisomal membrane protein 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PXMP4 mRNA PMID:38866337
12245225 GSS glutathione synthetase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GSS mRNA PMID:38866337
12245252 KCNMB4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of KCNMB4 mRNA PMID:27255383
12245574 BVES blood vessel epicardial substance gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of BVES mRNA PMID:38866337
12245748 H2AC13 H2A clustered histone 13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of H2AC11 mRNA PMID:38866337
12245796 PPP2R5A protein phosphatase 2 regulatory subunit B'alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPP2R5A mRNA PMID:38866337
12246481 SOD1 superoxide dismutase 1 gene CHEBI:37537 phorbol 13-acetate 12-myristate affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D013755 SOD1 protein affects the susceptibility to Tetradecanoylphorbol Acetate PMID:6333936
12246481 SOD1 superoxide dismutase 1 gene CHEBI:7449 nafenopin affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D009255 SOD1 protein affects the susceptibility to Nafenopin PMID:6333936
12246481 SOD1 superoxide dismutase 1 gene CHEBI:77649 2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D009255 SOD1 protein affects the susceptibility to Nafenopin PMID:6333936
12246481 SOD1 superoxide dismutase 1 gene CHEBI:8069 phenobarbital affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D010634 SOD1 protein affects the susceptibility to Phenobarbital PMID:6333936
12246503 ADRB2 adrenoceptor beta 2 gene CHEBI:135592 amosulalol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C032473 amosulalol binds to and results in decreased activity of ADRB2 protein PMID:6129981
12246503 ADRB2 adrenoceptor beta 2 gene CHEBI:18357 (R)-noradrenaline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009638 [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased secretion of Norepinephrine PMID:2884805
12246503 ADRB2 adrenoceptor beta 2 gene CHEBI:8499 propranolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011433 [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased secretion of Norepinephrine PMID:2884805
12246586 TTR transthyretin gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of TTR mRNA] PMID:25419811
12246586 TTR transthyretin gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of TTR mRNA] PMID:25419811
12246586 TTR transthyretin gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of TTR mRNA] PMID:25419811
12246586 TTR transthyretin gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of TTR mRNA] PMID:25419811
12246909 MIR15B microRNA mir-15b gene CHEBI:17833 gentamycin affects expression EXP E RGD:6480464 20210608 CTD MESH:D005839 Gentamicins affects the expression of MIR15B mRNA PMID:33290828
12246909 MIR15B microRNA mir-15b gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR15B PMID:40036580
12247034 PLN phospholamban gene CHEBI:40279 allopurinol affects expression EXP E RGD:6480464 20191114 CTD MESH:D000493 Allopurinol affects the expression of PLN mRNA; Allopurinol affects the expression of PLN protein; Allopurinol affects the expression of PLN protein modified form PMID:17071724
12247066 NMB neuromedin B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NMB mRNA PMID:38866337
12247089 EXTL3 exostosin like glycosyltransferase 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EXTL3 mRNA PMID:38866337
12248238 NSDHL NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NSDHL mRNA PMID:38866337
12248831 NAPA NSF attachment protein alpha gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of NAPA protein PMID:32991862
12249132 VPS33A VPS33A core subunit of CORVET and HOPS complexes gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS33A mRNA PMID:27255383
12249312 UROS uroporphyrinogen III synthase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of UROS mRNA PMID:22747577
12249369 RHOQ ras homolog family member Q gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RHOQ mRNA PMID:38866337
12249412 FABP5 fatty acid binding protein 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FABP5 mRNA PMID:38866337
12249493 AIFM1 apoptosis inducing factor mitochondria associated 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AIFM1 mRNA PMID:38866337
12249597 SFRP4 secreted frizzled related protein 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SFRP4 mRNA PMID:38866337
12249738 ELK4 ETS transcription factor ELK4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ELK4 mRNA PMID:38866337
12249792 VCPKMT valosin containing protein lysine methyltransferase gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of VCPKMT mRNA PMID:22747577
12250216 NCF1 neutrophil cytosolic factor 1 gene CHEBI:32020 pitavastatin decreases expression EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in decreased expression of NCF1 mRNA PMID:15502390
12250216 NCF1 neutrophil cytosolic factor 1 gene CHEBI:71260 pitavastatin(1-) decreases expression EXP E RGD:6480464 20191114 CTD MESH:C108475 pitavastatin results in decreased expression of NCF1 mRNA PMID:15502390
12250353 CAV1 caveolin 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of CAV1 mRNA PMID:27255383
12250353 CAV1 caveolin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CAV1 mRNA PMID:38866337
12251375 IZUMO4 IZUMO family member 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IZUMO4 mRNA PMID:38866337
12251497 UST uronyl 2-sulfotransferase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of UST mRNA PMID:38866337
12251833 SNX17 sorting nexin 17 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of SNX17 mRNA PMID:27255383
12251955 NPAT nuclear protein, coactivator of histone transcription gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NPAT mRNA PMID:38866337
12252074 NPPA natriuretic peptide A gene CHEBI:18357 (R)-noradrenaline increases expression EXP E RGD:6480464 20191114 CTD MESH:D009638 Norepinephrine results in increased expression of NPPA protein PMID:8952593
12252074 NPPA natriuretic peptide A gene CHEBI:28918 (R)-adrenaline affects abundance EXP E RGD:6480464 20191114 CTD MESH:D004837 NPPA protein affects the abundance of Epinephrine PMID:2951327
12252074 NPPA natriuretic peptide A gene CHEBI:41879 dexamethasone increases expression EXP E RGD:6480464 20191114 CTD MESH:D003907 Dexamethasone results in increased expression of NPPA protein PMID:1934541
12252074 NPPA natriuretic peptide A gene CHEBI:4784 enalapril decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004656 Enalapril results in decreased expression of NPPA protein PMID:12019275
12252074 NPPA natriuretic peptide A gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 FR 173657 inhibits the reaction [Enalapril results in decreased expression of NPPA protein] PMID:12019275
12252074 NPPA natriuretic peptide A gene CHEBI:8499 propranolol increases expression EXP E RGD:6480464 20191114 CTD MESH:D011433 Propranolol results in increased expression of NPPA protein PMID:2566282
12252219 TNFSF10 TNF superfamily member 10 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TNFSF10 mRNA PMID:22747577
12252592 CHMP4B charged multivesicular body protein 4B gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of CHMP4B mRNA PMID:27255383
12252616 APMAP adipocyte plasma membrane associated protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of APMAP mRNA PMID:38866337
12252833 ALOX5 arachidonate 5-lipoxygenase gene CHEBI:10112 zileuton decreases activity EXP E RGD:6480464 20191114 CTD MESH:C063449 zileuton results in decreased activity of ALOX5 protein PMID:1618819
12253003 NFIA nuclear factor I A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NFIA mRNA PMID:38866337
12253291 CLEC2B C-type lectin domain family 2 member B gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of CLEC2B mRNA PMID:22747577
12253550 KCNK16 potassium two pore domain channel subfamily K member 16 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250325 CTD MESH:C006780 bisphenol A results in decreased expression of KCNK16 mRNA PMID:38866337
12253882 IL10RB interleukin 10 receptor subunit beta gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IL10RB mRNA PMID:38866337
12253987 AGRN agrin gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of AGRN mRNA PMID:22747577
12254561 BLOC1S1 biogenesis of lysosomal organelles complex 1 subunit 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of BLOC1S1 mRNA PMID:27255383
12254844 GLUL glutamate-ammonia ligase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GLUL mRNA PMID:38866337
12255615 MIR203 microRNA mir-203 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR203 PMID:40036580
12255685 TARDBP TAR DNA binding protein gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of TARDBP protein PMID:22747577
12255827 RAPGEF3 Rap guanine nucleotide exchange factor 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RAPGEF3 mRNA PMID:38866337
12256662 CAMK1D calcium/calmodulin dependent protein kinase ID gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of CAMK1D mRNA PMID:27255383
12257206 TMED2 transmembrane p24 trafficking protein 2 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TMED2 mRNA PMID:27255383
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:168067 Acetyl tributyl citrate increases activity EXP E RGD:6480464 20210504 CTD MESH:C014953 2-acetyltributylcitrate results in increased activity of NR1I2 protein PMID:21742782
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:28077 rifampicin increases activity EXP E RGD:6480464 20191114 CTD MESH:D012293 Rifampin results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:31429 colforsin daropate hydrochloride increases activity EXP E RGD:6480464 20191114 CTD MESH:D005576 Colforsin results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:3764 clotrimazole increases activity EXP E RGD:6480464 20191114 CTD MESH:D003022 Clotrimazole results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:45409 ritonavir increases activity EXP E RGD:6480464 20191114 CTD MESH:D019438 Ritonavir results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:45735 troleandomycin increases activity EXP E RGD:6480464 20191114 CTD MESH:D014217 Troleandomycin results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:47318 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases activity EXP E RGD:6480464 20191114 CTD MESH:C475093 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:585948 felodipine increases activity EXP E RGD:6480464 20191114 CTD MESH:D015736 Felodipine results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:77260 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases activity EXP E RGD:6480464 20191114 CTD MESH:D009853 Omeprazole results in increased activity of NR1I2 protein PMID:27732639
12257278 NR1I2 nuclear receptor subfamily 1 group I member 2 gene CHEBI:7772 omeprazole increases activity EXP E RGD:6480464 20191114 CTD MESH:D009853 Omeprazole results in increased activity of NR1I2 protein PMID:27732639
12257843 DKK1 dickkopf WNT signaling pathway inhibitor 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DKK1 mRNA PMID:38866337
12257886 DOCK9 dedicator of cytokinesis 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DOCK9 mRNA PMID:38866337
12258079 MIR221 microRNA mir-221 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR221 PMID:40036580
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16240 hydrogen peroxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein PMID:23816505
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] PMID:23816505
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005978 Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] PMID:23816505
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:17924 D-glucitol increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D013012 Sorbitol results in increased phosphorylation of MAPK1 protein PMID:12639917
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:26710 sodium chloride increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased phosphorylation of MAPK1 protein PMID:23816505
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] PMID:23816505
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:27563 arsenic atom increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D001151 Arsenic results in increased phosphorylation of MAPK1 protein PMID:29306782
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] PMID:23816505
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:30621 diarsenic trioxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006632 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein PMID:23236503
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:31429 colforsin daropate hydrochloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005576 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein PMID:12639917
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:37537 phorbol 13-acetate 12-myristate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013755 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK1 protein PMID:12639917
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:47217 arsane increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D001151 Arsenic results in increased phosphorylation of MAPK1 protein PMID:29306782
12258672 MAPK1 mitogen-activated protein kinase 1 gene CHEBI:49900 arsenous acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C032793 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein PMID:23236503
12258685 AP1G1 adaptor related protein complex 1 subunit gamma 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AP1G1 mRNA PMID:38866337
12258978 TBC1D14 TBC1 domain family member 14 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of TBC1D14 mRNA PMID:22747577
12259005 GCNT4 glucosaminyl (N-acetyl) transferase 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GCNT4 mRNA PMID:38866337
12259204 NCL nucleolin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NCL mRNA PMID:38866337
12259272 EP300 E1A binding protein p300 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20200128 CTD MESH:C059514 [[Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] which results in decreased activity of EP300 protein] which results in decreased acetylation of RELA protein; [Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] inhibits the reaction [TNFSF11 protein results in increased acetylation of and results in increased activity of RELA protein]; [Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] which results in decreased activity of EP300 protein; Resveratrol promotes the reaction [[SIRT1 protein binds to EP300 protein] which binds to RUNX2 protein]; Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein] PMID:21239502
12260125 CASP8 caspase 8 gene CHEBI:132230 marbofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:C080260 marbofloxacin results in increased expression of CASP8 mRNA PMID:31005593
12260125 CASP8 caspase 8 gene CHEBI:132230 marbofloxacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C080260 TNFRSF1A mRNA promotes the reaction [marbofloxacin results in increased expression of CASP8 mRNA] PMID:31005593
12260125 CASP8 caspase 8 gene CHEBI:51403 1,4-phenylenediamine increases activity EXP E RGD:6480464 20191114 CTD MESH:C029728 4-phenylenediamine results in increased activity of CASP8 protein PMID:20156547
12260125 CASP8 caspase 8 gene CHEBI:51403 1,4-phenylenediamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C029728 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [4-phenylenediamine results in increased activity of CASP8 protein] PMID:20156547
12260125 CASP8 caspase 8 gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of CASP8 mRNA PMID:24582689
12260125 CASP8 caspase 8 gene CHEBI:7731 ofloxacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015242 TNFRSF1A mutant form inhibits the reaction [Ofloxacin results in increased expression of CASP8 mRNA] PMID:24582689
12260493 MIR660 microRNA mir-660 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR660 PMID:40036580
12261106 RABGAP1 RAB GTPase activating protein 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RABGAP1 mRNA PMID:38866337
12261167 IL1R1 interleukin 1 receptor type 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IL1R1 mRNA PMID:38866337
12261435 ACADVL acyl-CoA dehydrogenase very long chain gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of ACADVL protein PMID:19952500
12261536 HOXA2 homeobox A2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HOXA2 mRNA PMID:38866337
12261638 MLLT11 MLLT11 transcription factor 7 cofactor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MLLT11 mRNA PMID:38866337
12261866 BHMT betaine--homocysteine S-methyltransferase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of BHMT protein PMID:19952500
12262009 GYPC glycophorin C gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GYPC mRNA PMID:38866337
12262056 PHF10 PHD finger protein 10 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PHF10 mRNA PMID:22747577
12262685 HILPDA hypoxia inducible lipid droplet associated gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HILPDA mRNA PMID:38866337
12262691 CTNS cystinosin, lysosomal cystine transporter gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CTNS mRNA PMID:38866337
12263390 DLGAP1 DLG associated protein 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of DLGAP1 mRNA PMID:22747577
12263533 MAB21L2 mab-21 like 2 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of MAB21L2 mRNA] PMID:25419811
12263533 MAB21L2 mab-21 like 2 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of MAB21L2 mRNA] PMID:25419811
12263533 MAB21L2 mab-21 like 2 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of MAB21L2 mRNA] PMID:25419811
12263533 MAB21L2 mab-21 like 2 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of MAB21L2 mRNA] PMID:25419811
12264134 DSTYK dual serine/threonine and tyrosine protein kinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DSTYK mRNA PMID:38866337
12264151 CAST calpastatin gene CHEBI:9241 spironolactone increases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in increased expression of CAST protein PMID:20082611
12264323 TTLL1 TTL family tubulin polyglutamylase complex subunit L1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of TTLL1 mRNA PMID:22747577
12264445 INSIG1 insulin induced gene 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of INSIG1 mRNA PMID:38866337
12264551 RBP4 retinol binding protein 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RBP4 mRNA PMID:38866337
12265449 TCEAL3 transcription elongation factor A like 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TCEAL3 mRNA PMID:38866337
12265583 ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of ATP1A1 mRNA PMID:27255383
12266651 LAMC2 laminin subunit gamma 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LAMC2 mRNA PMID:38866337
12267221 AIG1 androgen induced 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of AIG1 mRNA PMID:22747577
12267457 ALAS1 5'-aminolevulinate synthase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ALAS1 mRNA PMID:38866337
12267755 HYAL3 hyaluronidase 3 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of HYAL3 mRNA PMID:22747577
12268039 ACTA2 actin alpha 2, smooth muscle gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of ACTA2 mRNA; ochratoxin A results in increased expression of ACTA2 protein PMID:33543323
12268039 ACTA2 actin alpha 2, smooth muscle gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of ACTA2 mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of ACTA2 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of ACTA2 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of ACTA2 protein] PMID:33543323
12269304 HSP90AA1 heat shock protein 90 alpha family class A member 1 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of HSP90AA1 protein PMID:32991862
12269304 HSP90AA1 heat shock protein 90 alpha family class A member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HSP90AA1 mRNA PMID:38866337
12269544 CYSRT1 cysteine rich tail 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CYSRT1 mRNA PMID:38866337
12269572 ABCA9 ATP binding cassette subfamily A member 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ABCA9 mRNA PMID:38866337
12270112 TNFAIP8L3 TNF alpha induced protein 8 like 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TNFAIP8L3 mRNA PMID:38866337
12270363 TGFBR2 transforming growth factor beta receptor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TGFBR2 mRNA PMID:38866337
12271009 KIDINS220 kinase D interacting substrate 220 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KIDINS220 mRNA PMID:38866337
12271253 PAK1 p21 (RAC1) activated kinase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PAK1 mRNA PMID:38866337
12272567 WAPL WAPL cohesin release factor gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of WAPAL mRNA PMID:22747577
12274072 RCN1 reticulocalbin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RCN1 mRNA PMID:38866337
12274081 IFT122 intraflagellar transport 122 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IFT122 mRNA PMID:38866337
12274482 TRIM63 tripartite motif containing 63 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TRIM63 mRNA PMID:38866337
12274635 MRM3 mitochondrial rRNA methyltransferase 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MRM3 mRNA PMID:38866337
12274806 QPCT glutaminyl-peptide cyclotransferase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of QPCT mRNA PMID:38866337
12275117 AGT angiotensinogen gene CHEBI:145568 cilazapril monohydrate decreases expression EXP E RGD:6480464 20200107 CTD MESH:D017315 Cilazapril results in decreased expression of AGT protein PMID:2419701
12275117 AGT angiotensinogen gene CHEBI:26523 reactive oxygen species multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017382 Reactive Oxygen Species inhibits the reaction [AGT protein modified form results in increased susceptibility to Serotonin] PMID:8021468
12275117 AGT angiotensinogen gene CHEBI:27584 aldosterone increases abundance EXP E RGD:6480464 20191114 CTD MESH:D000450 AGT results in increased abundance of Aldosterone PMID:2831029
12275117 AGT angiotensinogen gene CHEBI:28790 serotonin increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D012701 AGT protein modified form results in increased susceptibility to Serotonin PMID:8021468
12275117 AGT angiotensinogen gene CHEBI:28790 serotonin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012701 Deferoxamine inhibits the reaction [AGT protein modified form results in increased susceptibility to Serotonin]; Reactive Oxygen Species inhibits the reaction [AGT protein modified form results in increased susceptibility to Serotonin] PMID:8021468
12275117 AGT angiotensinogen gene CHEBI:4356 desferrioxamine B multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003676 Deferoxamine inhibits the reaction [AGT protein modified form results in increased susceptibility to Serotonin] PMID:8021468
12276421 MT2A metallothionein 1H gene CHEBI:31823 mercury dichloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D008627 Mercuric Chloride results in increased expression of MT2 mRNA PMID:15590114
12276501 DKK2 dickkopf WNT signaling pathway inhibitor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DKK2 mRNA PMID:38866337
12276730 H1-5 H1.5 linker histone, cluster member gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of H1-5 mRNA PMID:38866337
12277246 USP4 ubiquitin specific peptidase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of USP4 mRNA PMID:38866337
12277402 CRH corticotropin releasing hormone gene CHEBI:17650 cortisol increases abundance EXP E RGD:6480464 20191114 CTD MESH:D006854 CRH protein results in increased abundance of Hydrocortisone PMID:2831029
12277749 WASHC2C WASH complex subunit 2C gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of WASHC2C mRNA PMID:38866337
12278189 MIR107 microRNA mir-107 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR107 PMID:40036580
12278653 GH1 growth hormone gene CHEBI:3757 clonidine (imino form) increases secretion EXP E RGD:6480464 20250325 CTD MESH:D003000 Clonidine results in increased secretion of GH1 protein PMID:6248808
12278653 GH1 growth hormone gene CHEBI:46631 clonidine increases secretion EXP E RGD:6480464 20250325 CTD MESH:D003000 Clonidine results in increased secretion of GH1 protein PMID:6248808
12278653 GH1 growth hormone gene CHEBI:46632 clonidine (amino form) increases secretion EXP E RGD:6480464 20250325 CTD MESH:D003000 Clonidine results in increased secretion of GH1 protein PMID:6248808
12278725 SFT2D1 SFT2 domain containing 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of SFT2D1 mRNA PMID:27255383
12278777 SLC25A12 solute carrier family 25 member 12 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of SLC25A12 protein PMID:32991862
12278777 SLC25A12 solute carrier family 25 member 12 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of SLC25A12 mRNA PMID:22747577
12278824 TM2D2 TM2 domain containing 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TM2D2 mRNA PMID:22747577
12278919 GMPR guanosine monophosphate reductase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GMPR mRNA PMID:38866337
12279055 CRYZ crystallin zeta gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of CRYZ protein PMID:19952500
12279429 EPHX1 epoxide hydrolase 1 gene CHEBI:17907 styrene oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C013690 CYP3A12 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] PMID:12051674
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:135004 nefiracetam affects expression EXP E RGD:6480464 20191114 CTD MESH:C058876 nefiracetam affects the expression of PTGS2 mRNA PMID:16105799
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:135004 nefiracetam increases expression EXP E RGD:6480464 20191114 CTD MESH:C058876 nefiracetam results in increased expression of PTGS2 protein PMID:16105799
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP E RGD:6480464 20191114 CTD MESH:D013749 Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA; Tetrachlorodibenzodioxin results in increased expression of PTGS2 protein PMID:8660662
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:32243 tolfenamic acid decreases expression EXP E RGD:6480464 20191114 CTD MESH:C009500 tolfenamic acid results in decreased expression of PTGS2 mRNA PMID:15198222
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PTGS2 mRNA PMID:38866337
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:364453 carprofen decreases expression EXP E RGD:6480464 20191114 CTD MESH:C007005 carprofen results in decreased expression of PTGS2 mRNA PMID:15198222
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:44445 nimesulide decreases expression EXP E RGD:6480464 20191114 CTD MESH:C012655 nimesulide results in decreased expression of PTGS2 mRNA PMID:15198222
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:4909 etodolac decreases expression EXP E RGD:6480464 20191114 CTD MESH:D017308 Etodolac results in decreased expression of PTGS2 mRNA PMID:15198222
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:5855 ibuprofen increases expression EXP E RGD:6480464 20191114 CTD MESH:D007052 Ibuprofen results in increased expression of PTGS2 protein PMID:16105799
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:73458 NS-398 decreases expression EXP E RGD:6480464 20191114 CTD MESH:C080955 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PTGS2 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of PTGS2 protein PMID:12857884|PMID:15198222
12279597 PTGS2 prostaglandin-endoperoxide synthase 2 gene CHEBI:9352 sulindac decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013467 Sulindac results in decreased expression of PTGS2 protein PMID:12857884
12279693 ACTL7A actin like 7A gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ACTL7A mRNA PMID:22747577
12279734 LGR4 leucine rich repeat containing G protein-coupled receptor 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LGR4 mRNA PMID:38866337
12280045 MIF macrophage migration inhibitory factor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MIF mRNA PMID:38866337
12280069 TMEM42 transmembrane protein 42 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM42 mRNA PMID:38866337
12280604 ACOX2 acyl-CoA oxidase 2 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of ACOX2 mRNA PMID:19952500
12280894 CIAPIN1 cytokine induced apoptosis inhibitor 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of CIAPIN1 mRNA PMID:22747577
12281399 POMC proopiomelanocortin gene CHEBI:17650 cortisol increases abundance EXP E RGD:6480464 20191114 CTD MESH:D006854 POMC protein results in increased abundance of Hydrocortisone PMID:2831029
12281399 POMC proopiomelanocortin gene CHEBI:18357 (R)-noradrenaline increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D009638 POMC protein results in increased susceptibility to Norepinephrine PMID:6279499
12281399 POMC proopiomelanocortin gene CHEBI:27584 aldosterone increases abundance EXP E RGD:6480464 20191114 CTD MESH:D000450 POMC protein results in increased abundance of Aldosterone PMID:2831029
12281399 POMC proopiomelanocortin gene CHEBI:6954 Mitotane increases expression EXP E RGD:6480464 20191114 CTD MESH:D008939 Mitotane results in increased expression of POMC protein alternative form PMID:8453685
12281399 POMC proopiomelanocortin gene CHEBI:7457 Nalmefene increases expression EXP E RGD:6480464 20191114 CTD MESH:C038981 nalmefene results in increased expression of POMC protein alternative form PMID:3026683
12281399 POMC proopiomelanocortin gene CHEBI:7459 naloxone increases expression EXP E RGD:6480464 20191114 CTD MESH:D009270 Naloxone results in increased expression of POMC protein PMID:8277081
12281399 POMC proopiomelanocortin gene CHEBI:7596 nitroprusside increases expression EXP E RGD:6480464 20191114 CTD MESH:D009599 Nitroprusside results in increased expression of POMC protein PMID:2831029
12281794 CDYL chromodomain Y like gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CDYL mRNA PMID:38866337
12282219 CFAP119 cilia and flagella associated protein 119 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CCDC189 mRNA PMID:38866337
12282837 DEF6 DEF6 guanine nucleotide exchange factor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DEF6 mRNA PMID:38866337
12283124 CCDC141 coiled-coil domain containing 141 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CCDC141 mRNA PMID:38866337
12284241 BCAT1 branched chain amino acid transaminase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of BCAT1 mRNA PMID:38866337
12284259 ABCB11 ATP binding cassette subfamily B member 11 gene CHEBI:75379 blebbistatin decreases localization EXP E RGD:6480464 20191114 CTD MESH:C472645 blebbistatin results in decreased localization of ABCB11 protein PMID:15826951
12284323 KLF3 KLF transcription factor 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KLF3 mRNA PMID:38866337
12284512 THEMIS2 thymocyte selection associated family member 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of THEMIS2 mRNA PMID:22747577
12284676 VPS26A VPS26, retromer complex component A gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS26A mRNA PMID:27255383
12284723 ARRB1 arrestin beta 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ARRB1 mRNA PMID:38866337
12284972 FAM98A family with sequence similarity 98 member A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM98A mRNA PMID:38866337
12286036 SPG11 SPG11 vesicle trafficking associated, spatacsin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SPG11 mRNA PMID:38866337
12286191 LCP1 lymphocyte cytosolic protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LCP1 mRNA PMID:38866337
12286979 GARS1 glycyl-tRNA synthetase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GARS1 mRNA PMID:38866337
12287062 MYC MYC proto-oncogene, bHLH transcription factor gene CHEBI:31401 cilostazol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C045645 Cilostazol results in decreased expression of MYC mRNA PMID:19545562
12287448 DPYSL3 dihydropyrimidinase like 3 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of DPYSL3 mRNA PMID:22747577
12287664 HLF HLF transcription factor, PAR bZIP family member gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HLF mRNA PMID:38866337
12288186 PFN4 profilin family member 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PFN4 mRNA PMID:38866337
12288301 MMP9 matrix metallopeptidase 9 gene CHEBI:15379 dioxygen multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D010100 Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of MMP9 protein] PMID:18339021
12288301 MMP9 matrix metallopeptidase 9 gene CHEBI:17883 hydrogen chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D006851 Hydrochloric Acid results in increased expression of MMP9 protein PMID:18339021
12288301 MMP9 matrix metallopeptidase 9 gene CHEBI:17883 hydrogen chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006851 Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of MMP9 protein] PMID:18339021
12288301 MMP9 matrix metallopeptidase 9 gene CHEBI:9241 spironolactone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in decreased expression of MMP9 protein PMID:20082611
12288501 PELI1 pellino E3 ubiquitin protein ligase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PELI1 mRNA PMID:38866337
12288654 RBPJL recombination signal binding protein for immunoglobulin kappa J region like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RBPJL mRNA PMID:38866337
12289184 H2AC25 H2A clustered histone 25 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of H2AC25 mRNA PMID:38866337
12289273 MGST3 microsomal glutathione S-transferase 3 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of MGST3 mRNA PMID:19952500
12289517 FRYL FRY like transcription coactivator gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FRYL mRNA PMID:38866337
12289775 CEP68 centrosomal protein 68 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CEP68 mRNA PMID:38866337
12289830 CAPG capping actin protein, gelsolin like gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CAPG protein PMID:22747577
12290254 ANK3 ankyrin 3 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of ANK3 mRNA PMID:27255383
12290491 GDI1 GDP dissociation inhibitor 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of GDI1 protein PMID:19952500
12290611 UCHL3 ubiquitin C-terminal hydrolase L3 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of UCHL3 protein PMID:22747577
12290805 FGD6 FYVE, RhoGEF and PH domain containing 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FGD6 mRNA PMID:38866337
12290835 PLEKHA2 pleckstrin homology domain containing A2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PLEKHA2 mRNA PMID:38866337
12290979 SHMT1 serine hydroxymethyltransferase 1 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of SHMT1 protein PMID:19952500
12291223 GLS2 glutaminase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GLS2 mRNA PMID:38866337
12291294 MIR20B microRNA mir-20b gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR20B PMID:40036580
12291816 CA12 carbonic anhydrase 12 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CA12 mRNA PMID:38866337
12291834 USP24 ubiquitin specific peptidase 24 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of USP24 mRNA PMID:38866337
12292092 KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KCNE4 mRNA PMID:38866337
12292179 RCAN1 regulator of calcineurin 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of RCAN1 mRNA PMID:22747577
12292561 TBC1D20 TBC1 domain family member 20 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TBC1D20 mRNA PMID:38866337
12292980 ZFAND5 zinc finger AN1-type containing 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZFAND5 mRNA PMID:38866337
12293225 SH3D19 SH3 domain containing 19 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SH3D19 mRNA PMID:38866337
12293409 CARMIL1 capping protein regulator and myosin 1 linker 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CARMIL1 mRNA PMID:38866337
12293737 AQR aquarius intron-binding spliceosomal factor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AQR mRNA PMID:38866337
12293829 HDHD3 haloacid dehalogenase like hydrolase domain containing 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HDHD3 mRNA PMID:38866337
12294383 ELOB elongin B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ELOB mRNA PMID:38866337
12294444 SLC6A9 solute carrier family 6 member 9 gene CHEBI:27617 monensin A affects localization EXP E RGD:6480464 20191114 CTD MESH:D008985 Monensin affects the localization of SLC6A9 protein PMID:19473961
12294444 SLC6A9 solute carrier family 6 member 9 gene CHEBI:27617 monensin A multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008985 Tetradecanoylphorbol Acetate promotes the reaction [Monensin affects the localization of SLC6A9 protein] PMID:19473961
12294444 SLC6A9 solute carrier family 6 member 9 gene CHEBI:37537 phorbol 13-acetate 12-myristate affects localization EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate affects the localization of SLC6A9 protein PMID:19473961
12294444 SLC6A9 solute carrier family 6 member 9 gene CHEBI:37537 phorbol 13-acetate 12-myristate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013755 Tetradecanoylphorbol Acetate promotes the reaction [Monensin affects the localization of SLC6A9 protein] PMID:19473961
12294532 TSG101 tumor susceptibility 101 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TSG101 mRNA PMID:27255383
12295760 RSPO1 R-spondin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RSPO1 mRNA PMID:38866337
12295839 SNX15 sorting nexin 15 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of SNX15 mRNA PMID:27255383
12295910 TMSB10 thymosin beta 10 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMSB10 mRNA PMID:38866337
12296205 NTRK2 neurotrophic receptor tyrosine kinase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NTRK2 mRNA PMID:38866337
12296742 DLGAP5 DLG associated protein 5 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of DLGAP5 mRNA PMID:22747577
12296991 SP1 Sp1 transcription factor gene CHEBI:26710 sodium chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased expression of SP1 protein PMID:23816505
12296991 SP1 Sp1 transcription factor gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 pyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of SP1 protein]; Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]; U 0126 inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; U 0126 inhibits the reaction [Sodium Chloride results in increased expression of SP1 protein] PMID:23816505
12296991 SP1 Sp1 transcription factor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SP1 mRNA PMID:38866337
12296991 SP1 Sp1 transcription factor gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of SP1 protein] PMID:23816505
12297403 PNCK pregnancy up-regulated nonubiquitous CaM kinase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PNCK mRNA PMID:38866337
12297635 IDH2 isocitrate dehydrogenase (NADP(+)) 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IDH2 mRNA PMID:38866337
12297941 AGFG2 ArfGAP with FG repeats 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AGFG2 mRNA PMID:38866337
12298027 CELF2 CUGBP Elav-like family member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CELF2 mRNA PMID:38866337
12298322 LRIG3 leucine rich repeats and immunoglobulin like domains 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LRIG3 mRNA PMID:38866337
12299714 HADH hydroxyacyl-CoA dehydrogenase gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of HADH mRNA PMID:19952500
12299714 HADH hydroxyacyl-CoA dehydrogenase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of HADH mRNA PMID:19952500
12301253 KIF5A kinesin family member 5A gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of KIF5A mRNA PMID:27255383
12302000 SPAAR small regulatory polypeptide of amino acid response gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SPAAR mRNA PMID:38866337
12302016 RSPO3 R-spondin 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RSPO3 mRNA PMID:38866337
12302403 NPB neuropeptide B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NPB mRNA PMID:38866337
12302435 COMMD1 copper metabolism domain containing 1 gene CHEBI:28694 copper atom decreases export EXP E RGD:6480464 20191114 CTD MESH:D003300 COMMD1 gene mutant form results in decreased export of Copper PMID:20433422
12302435 COMMD1 copper metabolism domain containing 1 gene CHEBI:28694 copper atom increases abundance EXP E RGD:6480464 20191114 CTD MESH:D003300 COMMD1 gene mutant form results in increased abundance of Copper PMID:22879914
12302435 COMMD1 copper metabolism domain containing 1 gene CHEBI:30052 copper(0) decreases export EXP E RGD:6480464 20191114 CTD MESH:D003300 COMMD1 gene mutant form results in decreased export of Copper PMID:20433422
12302435 COMMD1 copper metabolism domain containing 1 gene CHEBI:30052 copper(0) increases abundance EXP E RGD:6480464 20191114 CTD MESH:D003300 COMMD1 gene mutant form results in increased abundance of Copper PMID:22879914
12302701 DYNLT4 dynein light chain Tctex-type 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DYNLT4 mRNA PMID:38866337
12303042 KNCN kinocilin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KNCN mRNA PMID:38866337
12303620 ETFDH electron transfer flavoprotein dehydrogenase gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ETFDH mRNA PMID:22747577
12304097 KCNJ3 potassium inwardly rectifying channel subfamily J member 3 gene CHEBI:15355 acetylcholine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000109 Acetylcholine promotes the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium] PMID:10666054
12304097 KCNJ3 potassium inwardly rectifying channel subfamily J member 3 gene CHEBI:26216 potassium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011188 [KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium; Acetylcholine promotes the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium]; Barium inhibits the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium] PMID:10666054
12304097 KCNJ3 potassium inwardly rectifying channel subfamily J member 3 gene CHEBI:32595 barium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001464 Barium inhibits the reaction [[KCNJ3 protein co-treated with KCNJ6 protein] results in increased transport of Potassium] PMID:10666054
12304129 GLRA1 glycine receptor alpha 1 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GLRA1 mRNA] PMID:25419811
12304129 GLRA1 glycine receptor alpha 1 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GLRA1 mRNA] PMID:25419811
12304129 GLRA1 glycine receptor alpha 1 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GLRA1 mRNA] PMID:25419811
12304129 GLRA1 glycine receptor alpha 1 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GLRA1 mRNA] PMID:25419811
12304168 CLMP CXADR like membrane protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CLMP mRNA PMID:38866337
12304674 HRC histidine rich calcium binding protein gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of HRC mRNA PMID:27255383
12305033 ABITRAM actin binding transcription modulator gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ABITRAM mRNA PMID:22747577
12305105 WDR11 WD repeat domain 11 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of WDR11 mRNA PMID:38866337
12305715 SLC47A1 solute carrier family 47 member 1 gene CHEBI:38000 uniconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C092705 uniconazole results in decreased activity of SLC47A1 protein PMID:36669674
12305715 SLC47A1 solute carrier family 47 member 1 gene CHEBI:81766 hexaconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C409722 hexaconazole results in decreased activity of SLC47A1 protein PMID:36669674
12305715 SLC47A1 solute carrier family 47 member 1 gene CHEBI:81781 tebuconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087114 tebuconazole results in decreased activity of SLC47A1 protein PMID:36669674
12305715 SLC47A1 solute carrier family 47 member 1 gene CHEBI:81970 penconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087058 penconazole results in decreased activity of SLC47A1 protein PMID:36669674
12305715 SLC47A1 solute carrier family 47 member 1 gene CHEBI:81980 triticonazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C412303 triticonazole results in decreased activity of SLC47A1 protein PMID:36669674
12305837 SENP1 SUMO specific peptidase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SENP1 mRNA PMID:38866337
12306176 UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20240806 CTD MESH:C526575 masitinib results in decreased expression of UQCC1 mRNA PMID:22747577
12306220 TMEM35A transmembrane protein 35A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM35A mRNA PMID:38866337
12306313 DHDH dihydrodiol dehydrogenase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DHDH mRNA PMID:38866337
12306340 ARMC12 armadillo repeat containing 12 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ARMC12 mRNA PMID:22747577
12306353 LOC474938 glutathione S-transferase A2 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of GSTA3 mRNA; Clofibrate results in decreased expression of GSTA3 protein PMID:19952500
12306353 LOC474938 glutathione S-transferase A2 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of GSTA3 protein PMID:19952500
12306536 MON2 MON2 homolog, regulator of endosome-to-Golgi trafficking gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MON2 mRNA PMID:38866337
12307834 ZDHHC15 zinc finger DHHC-type palmitoyltransferase 15 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZDHHC15 mRNA PMID:38866337
12308300 EML1 EMAP like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EML1 mRNA PMID:38866337
12308466 DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DNAJB5 mRNA PMID:38866337
12308896 PARP14 poly(ADP-ribose) polymerase family member 14 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PARP14 mRNA PMID:22747577
12309295 XIAP X-linked inhibitor of apoptosis gene CHEBI:28748 doxorubicin affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D004317 XIAP affects the susceptibility to Doxorubicin PMID:16953886
12309515 IL31RA interleukin 31 receptor A gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of IL31RA promoter PMID:33763461
12309515 IL31RA interleukin 31 receptor A gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of IL31RA promoter PMID:33763461
12309611 WDR20 WD repeat domain 20 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of WDR20 mRNA PMID:38866337
12309640 ST6GALNAC5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ST6GALNAC5 mRNA PMID:38866337
12309823 UROD uroporphyrinogen decarboxylase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of UROD protein PMID:22747577
12309873 TSC22D1 TSC22 domain family member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TSC22D1 mRNA PMID:38866337
12310019 HECTD1 HECT domain E3 ubiquitin protein ligase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HECTD1 mRNA PMID:38866337
12310262 TOX thymocyte selection associated high mobility group box gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TOX mRNA PMID:22747577
12310308 ZC3H12C zinc finger CCCH-type containing 12C gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ZC3H12C mRNA PMID:38866337
12310616 C28H10orf90 chromosome 28 C10orf90 homolog gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of C28H10ORF90 mRNA PMID:38866337
12310865 TEX28 testis expressed 28 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TEX28 mRNA PMID:38866337
12311221 PC pyruvate carboxylase gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of PC protein PMID:32991862
12311221 PC pyruvate carboxylase gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of PC protein PMID:19952500
12311476 TROAP trophinin associated protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TROAP mRNA PMID:38866337
12311506 RASGRP2 RAS guanyl releasing protein 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of RASGRP2 mRNA PMID:22747577
12311729 LPIN1 lipin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LPIN1 mRNA PMID:38866337
12312469 POR cytochrome p450 oxidoreductase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of POR mRNA PMID:22747577
12312848 DRD2 dopamine receptor D2 gene CHEBI:26421 pyridines multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011725 Pyridines analog binds to and results in decreased activity of DRD2 protein PMID:12593651
12312848 DRD2 dopamine receptor D2 gene CHEBI:8871 risperidone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D018967 Risperidone binds to and results in decreased activity of DRD2 protein PMID:16948927
12313864 SERPINF1 serpin family F member 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SERPINF1 mRNA PMID:38866337
12313960 RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RIMOC1 mRNA PMID:38866337
12314180 PRLR prolactin receptor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PRLR mRNA PMID:38866337
12314580 ADA adenosine deaminase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ADA mRNA PMID:38866337
12315254 SMC5 structural maintenance of chromosomes 5 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of SMC5 mRNA PMID:22747577
12316365 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PMAIP1 mRNA PMID:38866337
12316701 ACTN3 actinin alpha 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACTN3 mRNA PMID:38866337
12316830 WDR5 WD repeat domain 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of WDR5 mRNA PMID:38866337
12316868 TCEAL4 transcription elongation factor A (SII)-like 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TCEAL4 mRNA PMID:38866337
12317496 LOC607874 cystatin-C-like gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20210608 CTD MESH:D005839 Gentamicins results in increased expression of CST3 protein PMID:33290828
12317551 STRADA STE20 related adaptor alpha gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of STRADA mRNA PMID:38866337
12317599 STON1 stonin 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of STON1 mRNA PMID:27255383
12317599 STON1 stonin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of STON1 mRNA PMID:38866337
12318220 DNM1L dynamin 1 like gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of DNM1L mRNA PMID:27255383
12318345 RUFY1 RUN and FYVE domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RUFY1 mRNA PMID:38866337
12319071 BMP4 bone morphogenetic protein 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BMP4 mRNA PMID:38866337
12319222 AGO2 argonaute RISC catalytic component 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of AGO2 mRNA PMID:22747577
12319654 CYGB cytoglobin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CYGB mRNA PMID:38866337
12319922 PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PLOD2 mRNA PMID:38866337
12320140 RUNX2 RUNX family transcription factor 2 gene CHEBI:17154 nicotinamide decreases expression EXP E RGD:6480464 20210114 CTD MESH:D009536 Niacinamide results in decreased expression of RUNX2 protein PMID:22539994
12320140 RUNX2 RUNX family transcription factor 2 gene CHEBI:17154 nicotinamide increases acetylation EXP E RGD:6480464 20210114 CTD MESH:D009536 Niacinamide results in increased acetylation of RUNX2 protein PMID:22539994
12320140 RUNX2 RUNX family transcription factor 2 gene CHEBI:17154 nicotinamide multiple interactions EXP E RGD:6480464 20210114 CTD MESH:D009536 Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]; Resveratrol inhibits the reaction [Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]]; Resveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein]; Resveratrol inhibits the reaction [Niacinamide results in increased acetylation of RUNX2 protein] PMID:22539994
12320140 RUNX2 RUNX family transcription factor 2 gene CHEBI:27881 resveratrol decreases acetylation EXP E RGD:6480464 20210114 CTD MESH:C059514 Resveratrol results in decreased acetylation of RUNX2 protein PMID:22539994
12320140 RUNX2 RUNX family transcription factor 2 gene CHEBI:27881 resveratrol increases expression EXP E RGD:6480464 20210114 CTD MESH:C059514 Resveratrol results in increased expression of RUNX2 protein PMID:22539994
12320140 RUNX2 RUNX family transcription factor 2 gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20210114 CTD MESH:C059514 [Resveratrol results in increased activity of SIRT1 protein] promotes the reaction [SIRT1 protein binds to RUNX2 protein]; Resveratrol inhibits the reaction [Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]]; Resveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein]; Resveratrol inhibits the reaction [Niacinamide results in increased acetylation of RUNX2 protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in decreased expression of RUNX2 protein]; Resveratrol promotes the reaction [[SIRT1 protein binds to EP300 protein] which binds to RUNX2 protein]; Resveratrol promotes the reaction [SIRT1 protein binds to RUNX2 protein]; SIRT1 protein affects the reaction [Resveratrol results in decreased acetylation of RUNX2 protein] PMID:21239502|PMID:22539994
12320708 NIM1K NIM1 serine/threonine protein kinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NIM1K mRNA PMID:38866337
12321161 LOC477072 serotransferrin gene CHEBI:18248 iron atom increases export EXP E RGD:6480464 20191114 CTD MESH:D007501 TF protein results in increased export of Iron PMID:16806171
12321161 LOC477072 serotransferrin gene CHEBI:18248 iron atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007501 [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] PMID:16806171
12321161 LOC477072 serotransferrin gene CHEBI:82664 iron(0) increases export EXP E RGD:6480464 20191114 CTD MESH:D007501 TF protein results in increased export of Iron PMID:16806171
12321161 LOC477072 serotransferrin gene CHEBI:82664 iron(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007501 [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] PMID:16806171
12321204 SNAP23 synaptosome associated protein 23 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SNAP23 mRNA PMID:27255383
12321590 FZD6 frizzled class receptor 6 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FZD6 mRNA PMID:38866337
12321678 LRBA LPS responsive beige-like anchor protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LRBA mRNA PMID:38866337
12321774 MARF1 meiosis regulator and mRNA stability factor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MARF1 mRNA PMID:38866337
12322085 CHMP6 charged multivesicular body protein 6 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of CHMP6 mRNA PMID:27255383
12322318 BCAP29 B cell receptor associated protein 29 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of BCAP29 mRNA PMID:27255383
12322336 POSTN periostin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of POSTN mRNA PMID:38866337
12322434 DDIT4L DNA damage inducible transcript 4 like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DDIT4L mRNA PMID:38866337
12322767 SEPHS1 selenophosphate synthetase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SEPHS1 mRNA PMID:38866337
12323288 C5AR2 complement C5a receptor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of C5AR2 mRNA PMID:38866337
12323305 KHK ketohexokinase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KHK mRNA PMID:38866337
12323344 SMAGP small cell adhesion glycoprotein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SMAGP mRNA PMID:38866337
12323815 ACVR2A activin A receptor type 2A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACVR2A mRNA PMID:38866337
12323923 LOC478000 phytanoyl-CoA hydroxylase-like gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PHYH mRNA PMID:22747577
12324307 ZCCHC12 zinc finger CCHC-type containing 12 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZCCHC12 mRNA PMID:38866337
12324317 DCPS decapping enzyme, scavenger gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DCPS mRNA PMID:38866337
12324347 WDR1 WD repeat domain 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of WDR1 mRNA PMID:38866337
12324640 TERT telomerase reverse transcriptase gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013749 Tetrachlorodibenzodioxin results in decreased expression of TERT protein PMID:23850740
12324640 TERT telomerase reverse transcriptase gene CHEBI:64090 tert-butyl hydroperoxide increases activity EXP E RGD:6480464 20191114 CTD MESH:D020122 tert-Butylhydroperoxide results in increased activity of TERT protein PMID:14729356
12324659 UGP2 UDP-glucose pyrophosphorylase 2 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of UGP2 protein PMID:19952500
12324788 USP25 ubiquitin specific peptidase 25 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of USP25 mRNA PMID:38866337
12325106 TTC38 tetratricopeptide repeat domain 38 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TTC38 protein PMID:22747577
12325915 PARD3 par-3 family cell polarity regulator gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PARD3 mRNA PMID:38866337
12326190 ARHGDIG Rho GDP dissociation inhibitor gamma gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ARHGDIG mRNA PMID:38866337
12326443 DDRGK1 DDRGK domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DDRGK1 mRNA PMID:38866337
12326643 H2AC19 H2A clustered histone 19 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of H2AC15 mRNA PMID:38866337
12326803 PRPSAP2 phosphoribosyl pyrophosphate synthetase associated protein 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PRPSAP2 mRNA PMID:38866337
12327252 KLF1 KLF transcription factor 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KLF1 mRNA PMID:38866337
12327259 TCN2 transcobalamin 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TCN2 mRNA PMID:22747577
12327410 PPTC7 protein phosphatase targeting COQ7 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPTC7 mRNA PMID:38866337
12327617 LONRF1 LON peptidase N-terminal domain and ring finger 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of LONRF1 mRNA PMID:22747577
12328418 HCAR1 hydroxycarboxylic acid receptor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HCAR1 mRNA PMID:38866337
12328583 SERTAD3 SERTA domain containing 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SERTAD3 mRNA PMID:38866337
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:15365 acetylsalicylic acid decreases activity EXP E RGD:6480464 20191114 CTD MESH:D001241 Aspirin results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:31225 antipyrine decreases activity EXP E RGD:6480464 20191114 CTD MESH:D000983 Antipyrine results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:32169 Sulpyrine decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004177 Dipyrone results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:46195 paracetamol decreases activity EXP E RGD:6480464 20191114 CTD MESH:D000082 Acetaminophen results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:47381 diclofenac decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004008 Diclofenac results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:49662 indometacin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007213 Indomethacin results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:5855 ibuprofen decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007052 Ibuprofen results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:59033 metamizole sodium decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004177 Dipyrone results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328669 PTGS1 prostaglandin-endoperoxide synthase 1 gene CHEBI:8050 phenacetin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D010615 Phenacetin results in decreased activity of PTGS1 protein alternative form PMID:12242329
12328781 TRPC2 transient receptor potential cation channel subfamily C member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250401 CTD MESH:C006780 bisphenol A results in increased expression of TRPC2 mRNA PMID:38866337
12328996 FBH1 F-box DNA helicase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FBH1 mRNA PMID:38866337
12329539 POLA1 DNA polymerase alpha 1, catalytic subunit gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of POLA1 mRNA PMID:38866337
12330022 HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HNRNPH2 mRNA PMID:38866337
12330261 SNAPIN SNAP associated protein gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of SNAPIN mRNA PMID:27255383
12330954 GJA1 gap junction protein alpha 1 gene CHEBI:35807 N-nitrosodimethylamine decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004128 Dimethylnitrosamine results in decreased expression of GJA1 protein PMID:15736408
12330959 AR androgen receptor gene CHEBI:31547 eplerenone multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C414690 Eplerenone binds to and results in decreased activity of AR protein PMID:23242577
12330988 PRKDC protein kinase, DNA-activated, catalytic subunit gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PRKDC mRNA PMID:38866337
12331435 CASQ1 calsequestrin 1 gene CHEBI:45716 vorinostat decreases expression EXP E RGD:6480464 20191114 CTD MESH:C111237 Vorinostat results in decreased expression of CASQ1 mRNA PMID:27255383
12331744 MT1E metallothionein 1E gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250401 CTD MESH:C006780 bisphenol A results in increased expression of MT1E mRNA PMID:38866337
12332208 POC1B POC1 centriolar protein B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of POC1B mRNA PMID:38866337
12332311 SETD2 SET domain containing 2, histone lysine methyltransferase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SETD2 mRNA PMID:38866337
12332893 MIR93 microRNA mir-93 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR93 PMID:40036580
12333406 C10H12orf75 chromosome 10 C12orf75 homolog gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of C10H12ORF75 mRNA PMID:38866337
12333604 EGLN3 egl-9 family hypoxia inducible factor 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of EGLN3 mRNA PMID:38866337
12333919 APBB2 amyloid beta precursor protein binding family B member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of APBB2 mRNA PMID:38866337
12334213 MX2 MX dynamin like GTPase 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MX2 mRNA PMID:38866337
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:22984 calcium atom increases transport EXP E RGD:6480464 20191114 CTD MESH:D002118 SLC8A1 protein results in increased transport of Calcium PMID:15375168
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:22984 calcium atom increases uptake EXP E RGD:6480464 20191114 CTD MESH:D002118 SLC8A1 protein results in increased uptake of Calcium PMID:14660663
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:22984 calcium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased transport of Calcium]; 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased uptake of Calcium]; SEA 0400 inhibits the reaction [SLC8A1 protein results in increased uptake of Calcium] PMID:14660663|PMID:15375168
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:2663 amiodarone decreases activity EXP E RGD:6480464 20191114 CTD MESH:D000638 Amiodarone results in decreased activity of SLC8A1 protein PMID:15288574
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:29320 calcium(0) increases transport EXP E RGD:6480464 20191114 CTD MESH:D002118 SLC8A1 protein results in increased transport of Calcium PMID:15375168
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:29320 calcium(0) increases uptake EXP E RGD:6480464 20191114 CTD MESH:D002118 SLC8A1 protein results in increased uptake of Calcium PMID:14660663
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:29320 calcium(0) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002118 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased transport of Calcium]; 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased uptake of Calcium]; SEA 0400 inhibits the reaction [SLC8A1 protein results in increased uptake of Calcium] PMID:14660663|PMID:15375168
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:40279 allopurinol affects expression EXP E RGD:6480464 20191114 CTD MESH:D000493 Allopurinol affects the expression of SLC8A1 mRNA; Allopurinol affects the expression of SLC8A1 protein PMID:17071724
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 [Ranolazine co-treated with Enalapril] affects the expression of SLC8A1 protein PMID:18820026
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:6904 metoprolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008790 [Ranolazine co-treated with Metoprolol] affects the expression of SLC8A1 protein PMID:18820026
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:87681 ranolazine affects expression EXP E RGD:6480464 20191114 CTD MESH:D000069458 Ranolazine affects the expression of SLC8A1 protein PMID:18820026
12334269 SLC8A1 solute carrier family 8 member A1 gene CHEBI:87681 ranolazine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069458 [Ranolazine co-treated with Enalapril] affects the expression of SLC8A1 protein; [Ranolazine co-treated with Metoprolol] affects the expression of SLC8A1 protein PMID:18820026
12335203 CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of CACNB3 mRNA PMID:27255383
12335345 DLA-12 MHC class I DLA-12 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of DLA-12 mRNA PMID:22747577
12336159 NQO1 NAD(P)H quinone dehydrogenase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NQO1 mRNA PMID:38866337
12336473 IDH1 isocitrate dehydrogenase (NADP(+)) 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IDH1 mRNA PMID:38866337
12336473 IDH1 isocitrate dehydrogenase (NADP(+)) 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of IDH1 protein PMID:19952500
12336666 GPD1L glycerol-3-phosphate dehydrogenase 1 like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GPD1L mRNA PMID:38866337
12336959 MIR27A microRNA mir-27a gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR27A PMID:40036580
12337614 HSP90B1 heat shock protein 90 beta family member 1 gene CHEBI:29699 tunicamycin increases expression EXP E RGD:6480464 20191114 CTD MESH:D014415 Tunicamycin results in increased expression of HSP90B1 protein PMID:17416481
12337614 HSP90B1 heat shock protein 90 beta family member 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of HSP90B1 protein PMID:22747577
12337791 F11R F11 receptor gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of F11R mRNA PMID:38866337
12338015 SEC24B SEC24 homolog B, COPII coat complex component gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SEC24B mRNA PMID:27255383
12338361 NISCH nischarin gene CHEBI:3757 clonidine (imino form) affects binding EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine binds to NISCH protein PMID:24120658
12338361 NISCH nischarin gene CHEBI:3757 clonidine (imino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Guanine Nucleotides inhibits the reaction [Clonidine binds to NISCH protein] PMID:24120658
12338361 NISCH nischarin gene CHEBI:4466 dexmedetomidine affects activity EXP E RGD:6480464 20191114 CTD MESH:D020927 Dexmedetomidine affects the activity of NISCH PMID:7486159
12338361 NISCH nischarin gene CHEBI:46631 clonidine affects binding EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine binds to NISCH protein PMID:24120658
12338361 NISCH nischarin gene CHEBI:46631 clonidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Guanine Nucleotides inhibits the reaction [Clonidine binds to NISCH protein] PMID:24120658
12338361 NISCH nischarin gene CHEBI:46632 clonidine (amino form) affects binding EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine binds to NISCH protein PMID:24120658
12338361 NISCH nischarin gene CHEBI:46632 clonidine (amino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 Guanine Nucleotides inhibits the reaction [Clonidine binds to NISCH protein] PMID:24120658
12338361 NISCH nischarin gene CHEBI:5862 idazoxan multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D019329 Idazoxan binds to and results in decreased activity of NISCH protein PMID:8732285
12338361 NISCH nischarin gene CHEBI:93363 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole affects binding EXP E RGD:6480464 20191114 CTD MESH:D009278 Naphazoline binds to NISCH protein PMID:24120658
12338361 NISCH nischarin gene CHEBI:93363 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009278 Guanine Nucleotides inhibits the reaction [Naphazoline binds to NISCH protein] PMID:24120658
12338615 CASP9 caspase 9 gene CHEBI:192461 toosendanin increases cleavage EXP E RGD:6480464 20240604 CTD MESH:C036454 toosendanin results in increased cleavage of CASP9 protein PMID:36809669
12338615 CASP9 caspase 9 gene CHEBI:4629 diosgenin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004144 Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP9 protein] PMID:25446497
12338615 CASP9 caspase 9 gene CHEBI:51403 1,4-phenylenediamine increases activity EXP E RGD:6480464 20191114 CTD MESH:C029728 4-phenylenediamine results in increased activity of CASP9 protein PMID:20156547
12338615 CASP9 caspase 9 gene CHEBI:51403 1,4-phenylenediamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C029728 benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [4-phenylenediamine results in increased activity of CASP9 protein] PMID:20156547
12338615 CASP9 caspase 9 gene CHEBI:60579 calcium oxalate increases activity EXP E RGD:6480464 20191114 CTD MESH:D002129 Calcium Oxalate results in increased activity of CASP9 protein PMID:25446497
12338615 CASP9 caspase 9 gene CHEBI:60579 calcium oxalate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002129 Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP9 protein] PMID:25446497
12339104 XDH xanthine dehydrogenase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of XDH mRNA PMID:38866337
12339162 RND3 Rho family GTPase 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RND3 mRNA PMID:38866337
12339447 NREP neuronal regeneration related protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NREP mRNA PMID:38866337
12339800 VAMP8 vesicle associated membrane protein 8 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of VAMP8 mRNA PMID:38866337
12339868 MIR15A microRNA mir-15a gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR15A PMID:40036580
12340549 HPD 4-hydroxyphenylpyruvate dioxygenase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of HPD protein PMID:19952500
12340922 HMG20A high mobility group 20A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HMG20A mRNA PMID:38866337
12340943 KCNK1 potassium two pore domain channel subfamily K member 1 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of KCNK1 mRNA PMID:27255383
12341630 RASSF2 Ras association domain family member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RASSF2 mRNA PMID:38866337
12341758 AMN1 antagonist of mitotic exit network 1 homolog gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of AMN1 mRNA PMID:22747577
12342079 PDLIM5 PDZ and LIM domain 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PDLIM5 mRNA PMID:38866337
12342201 SLC47A2 solute carrier family 47 member 2 gene CHEBI:81766 hexaconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C409722 hexaconazole results in decreased activity of SLC47A2 protein PMID:36669674
12342201 SLC47A2 solute carrier family 47 member 2 gene CHEBI:81781 tebuconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087114 tebuconazole results in decreased activity of SLC47A2 protein PMID:36669674
12342201 SLC47A2 solute carrier family 47 member 2 gene CHEBI:81970 penconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087058 penconazole results in decreased activity of SLC47A2 protein PMID:36669674
12342289 HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HCN3 mRNA PMID:38866337
12342349 PDCD7 programmed cell death 7 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PDCD7 mRNA PMID:38866337
12342386 ISG15 ISG15 ubiquitin like modifier gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ISG15 mRNA PMID:38866337
12342392 IFNAR2 interferon alpha and beta receptor subunit 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IFNAR2 mRNA PMID:38866337
12342540 CANX calnexin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CANX mRNA PMID:38866337
12342642 ACAA1 acetyl-CoA acyltransferase 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of ACAA1 mRNA PMID:19952500
12342832 THRAP3 thyroid hormone receptor associated protein 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of THRAP3 mRNA PMID:38866337
12342941 KCTD13 potassium channel tetramerization domain containing 13 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KCTD13 mRNA PMID:38866337
12342968 SLA Src like adaptor gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of SLA mRNA PMID:22747577
12342992 EPB42 erythrocyte membrane protein band 4.2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EPB42 mRNA PMID:38866337
12343529 GNG2 G protein subunit gamma 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GNG2 mRNA PMID:38866337
12343543 CA9 carbonic anhydrase 9 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CA9 mRNA PMID:38866337
12344106 DCX doublecortin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DCX mRNA PMID:38866337
12344177 NDUFAF8 NADH:ubiquinone oxidoreductase complex assembly factor 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NDUFAF8 mRNA PMID:38866337
12344307 R3HDM2 R3H domain containing 2 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of R3HDM2 mRNA PMID:22747577
12344516 VIP vasoactive intestinal peptide gene CHEBI:27638 cobalt atom decreases expression EXP E RGD:6480464 20191114 CTD MESH:D003035 Cobalt results in decreased expression of VIP protein PMID:3711722
12344516 VIP vasoactive intestinal peptide gene CHEBI:28748 doxorubicin decreases expression EXP E RGD:6480464 20191114 CTD MESH:D004317 Doxorubicin results in decreased expression of VIP protein PMID:3711722
12344516 VIP vasoactive intestinal peptide gene CHEBI:8499 propranolol decreases expression EXP E RGD:6480464 20191114 CTD MESH:D011433 Propranolol results in decreased expression of VIP protein PMID:2566282
12344588 DHRS9 dehydrogenase/reductase 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DHRS9 mRNA PMID:38866337
12344768 ALB albumin gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of ALB mRNA] PMID:25419811
12344768 ALB albumin gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of ALB mRNA] PMID:25419811
12344768 ALB albumin gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of ALB mRNA] PMID:25419811
12344768 ALB albumin gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of ALB mRNA] PMID:25419811
12344792 CPT1A carnitine palmitoyltransferase 1A gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of CPT1A mRNA PMID:19952500
12344815 HSP70 heat shock protein 70 gene CHEBI:16243 quercetin decreases expression EXP E RGD:6480464 20230307 CTD MESH:D011794 Quercetin results in decreased expression of HSP70 protein PMID:17009600
12344815 HSP70 heat shock protein 70 gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20230307 CTD MESH:D008070 HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] PMID:32899721
12344815 HSP70 heat shock protein 70 gene CHEBI:22977 cadmium atom increases expression EXP E RGD:6480464 20230307 CTD MESH:D002104 Cadmium results in increased expression of HSP70 protein PMID:12915104
12344815 HSP70 heat shock protein 70 gene CHEBI:29678 sodium arsenite increases expression EXP E RGD:6480464 20230307 CTD MESH:C017947 sodium arsenite results in increased expression of HSP70 protein PMID:31940135
12344815 HSP70 heat shock protein 70 gene CHEBI:29678 sodium arsenite multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C017947 carvacrol promotes the reaction [sodium arsenite results in increased expression of HSP70 protein]; leucinostatin A promotes the reaction [sodium arsenite results in increased expression of HSP70 protein] PMID:31940135
12344815 HSP70 heat shock protein 70 gene CHEBI:29866 arsenite(3-) increases expression EXP E RGD:6480464 20230307 CTD MESH:C015001 arsenite results in increased expression of HSP70 mRNA PMID:32899721
12344815 HSP70 heat shock protein 70 gene CHEBI:29866 arsenite(3-) multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C015001 HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] PMID:32899721
12344815 HSP70 heat shock protein 70 gene CHEBI:3440 carvacrol multiple interactions EXP E RGD:6480464 20230307 CTD MESH:C073316 carvacrol promotes the reaction [sodium arsenite results in increased expression of HSP70 protein] PMID:31940135
12344815 HSP70 heat shock protein 70 gene CHEBI:45716 vorinostat decreases expression EXP E RGD:6480464 20230307 CTD MESH:C111237 Vorinostat results in decreased expression of HSP70 mRNA PMID:27255383
12344882 SH2D4A SH2 domain containing 4A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SH2D4A mRNA PMID:38866337
12345752 HACD1 3-hydroxyacyl-CoA dehydratase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HACD1 mRNA PMID:38866337
12346334 MTARC1 mitochondrial amidoxime reducing component 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MTARC1 mRNA PMID:38866337
12346549 MIR29C-1 microRNA mir-29c-1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MIR29C-1 mRNA PMID:38866337
12347185 DLA-64 MHC class I DLA-64 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of DLA-64 mRNA PMID:22747577
12347408 RELA RELA proto-oncogene, NF-kB subunit gene CHEBI:16412 lipopolysaccharide increases phosphorylation EXP E RGD:6480464 20220405 CTD MESH:D008070 Lipopolysaccharides results in increased phosphorylation of RELA protein PMID:32899721
12347408 RELA RELA proto-oncogene, NF-kB subunit gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20220405 CTD MESH:D008070 arsenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] PMID:32899721
12347408 RELA RELA proto-oncogene, NF-kB subunit gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 [[Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] which results in decreased activity of EP300 protein] which results in decreased acetylation of RELA protein; [Resveratrol promotes the reaction [SIRT1 protein binds to EP300 protein]] inhibits the reaction [TNFSF11 protein results in increased acetylation of and results in increased activity of RELA protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in increased acetylation of and results in increased localization of and results in increased activity of RELA protein]; Resveratrol inhibits the reaction [TNFSF11 protein results in increased localization of and results in increased activity of RELA protein] PMID:21239502
12347408 RELA RELA proto-oncogene, NF-kB subunit gene CHEBI:29866 arsenite(3-) multiple interactions EXP E RGD:6480464 20220405 CTD MESH:C015001 arsenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] PMID:32899721
12347408 RELA RELA proto-oncogene, NF-kB subunit gene CHEBI:73458 NS-398 decreases localization EXP E RGD:6480464 20191114 CTD MESH:C080955 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased localization of RELA protein PMID:12857884
12347408 RELA RELA proto-oncogene, NF-kB subunit gene CHEBI:9352 sulindac decreases localization EXP E RGD:6480464 20191114 CTD MESH:D013467 Sulindac results in decreased localization of RELA protein PMID:12857884
12348331 OR4D9D olfactory receptor family 4 subfamily D member 9D gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of OR4D9D mRNA PMID:38866337
12349018 RORB RAR related orphan receptor B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RORB mRNA PMID:38866337
12349829 SPINT3 serine peptidase inhibitor, Kunitz type 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SPINT3 mRNA PMID:38866337
12349882 ACAA2 acetyl-CoA acyltransferase 2 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of ACAA2 mRNA PMID:19952500
12349882 ACAA2 acetyl-CoA acyltransferase 2 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of ACAA2 mRNA PMID:19952500
12350101 NMS neuromedin S gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NMS mRNA PMID:38866337
12350299 PPP2R1B protein phosphatase 2 scaffold subunit Abeta gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPP2R1B mRNA PMID:38866337
12350797 HPS5 HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HPS5 mRNA PMID:38866337
12350950 RNASEL ribonuclease L gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RNASEL mRNA PMID:38866337
12350994 AOC2 amine oxidase copper containing 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AOC2 mRNA PMID:38866337
12351150 TNNI3K TNNI3 interacting kinase gene CHEBI:45716 vorinostat decreases expression EXP E RGD:6480464 20191114 CTD MESH:C111237 Vorinostat results in decreased expression of TNNI3K mRNA PMID:27255383
12351294 NAT9 N-acetyltransferase 9 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NAT9 mRNA PMID:38866337
12351879 CYP3A26 cytochrome P450 3A26 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of CYP3A26 mRNA PMID:19952500
12351879 CYP3A26 cytochrome P450 3A26 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of CYP3A26 mRNA PMID:19952500
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:10033 warfarin increases hydroxylation EXP E RGD:6480464 20191114 CTD MESH:D014859 CYP3A12 protein results in increased hydroxylation of Warfarin PMID:12637241
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:17907 styrene oxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C013690 CYP3A12 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] PMID:12051674
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of CYP3A12 mRNA PMID:19952500
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:47519 ketoconazole decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007654 Ketoconazole results in decreased activity of CYP3A12 protein PMID:15677349
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:47519 ketoconazole multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007654 Ketoconazole inhibits the reaction [CYP3A12 protein results in increased hydroxylation of Diazepam] PMID:15677349
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:49575 diazepam increases hydroxylation EXP E RGD:6480464 20191114 CTD MESH:D003975 CYP3A12 protein results in increased hydroxylation of Diazepam PMID:15677349
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:49575 diazepam multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003975 Ketoconazole inhibits the reaction [CYP3A12 protein results in increased hydroxylation of Diazepam] PMID:15677349
12351896 CYP3A12 cytochrome P-450 3A12 gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of CYP3A12 protein PMID:19952500
12352080 VAMP5 vesicle associated membrane protein 5 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of VAMP5 mRNA PMID:38866337
12352281 CHRDL1 chordin like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CHRDL1 mRNA PMID:38866337
12352311 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GGA2 mRNA PMID:38866337
12352790 ACSBG1 acyl-CoA synthetase bubblegum family member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACSBG1 mRNA PMID:38866337
12353051 DDAH1 dimethylarginine dimethylaminohydrolase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DDAH1 mRNA PMID:38866337
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:17361 cytidine 5'-monophosphate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003568 [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Hexachlorocyclohexane affects the activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate PMID:2579070
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:24848 inositol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007294 [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate; Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides] PMID:2579070
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:32888 gamma-hexachlorocyclohexane affects activity EXP E RGD:6480464 20191114 CTD MESH:D001556 Hexachlorocyclohexane affects the activity of CDIPT protein PMID:2579070
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:32888 gamma-hexachlorocyclohexane multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D001556 [Hexachlorocyclohexane affects the activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate PMID:2579070
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:39095 delta-hexachlorocyclohexane decreases activity EXP E RGD:6480464 20191114 CTD MESH:C086916 delta-hexachlorocyclohexane results in decreased activity of CDIPT protein PMID:2579070
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:39095 delta-hexachlorocyclohexane multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C086916 [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate PMID:2579070
12353587 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene CHEBI:53013 3'-CMP multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003568 [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Hexachlorocyclohexane affects the activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate PMID:2579070
12353617 TMEM260 transmembrane protein 260 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TMEM260 mRNA PMID:22747577
12354313 MYL6B myosin light chain 6B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MYL6B mRNA PMID:38866337
12354899 LHFPL6 LHFPL tetraspan subfamily member 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LHFPL6 mRNA PMID:38866337
12355366 CCL2 C-C motif chemokine ligand 2 gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of CCL2 promoter PMID:33763461
12355366 CCL2 C-C motif chemokine ligand 2 gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20210608 CTD MESH:D005839 Gentamicins results in increased expression of CCL2 protein PMID:33290828
12355366 CCL2 C-C motif chemokine ligand 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CCL2 mRNA PMID:38866337
12355366 CCL2 C-C motif chemokine ligand 2 gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of CCL2 promoter PMID:33763461
12355637 VRK3 VRK serine/threonine kinase 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of VRK3 mRNA PMID:38866337
12355683 ATOSA atos homolog A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM214A mRNA PMID:38866337
12356225 PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PIKFYVE mRNA PMID:38866337
12357133 MYL9 myosin light chain 9 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 MYL9 protein modified form affects the reaction [ABCB1 protein affects the transport of Digoxin analog] PMID:20510202
12358149 KIF5C kinesin family member 5C gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of KIF5C mRNA PMID:27255383
12358215 GPNMB glycoprotein nmb gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GPNMB mRNA PMID:38866337
12358294 BTBD7 BTB domain containing 7 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BTBD7 mRNA PMID:38866337
12358542 KRT18 keratin 18 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of KRT18 protein PMID:19952500
12358580 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PFKFB2 mRNA PMID:38866337
12358831 ALDH5A1 aldehyde dehydrogenase 5 family member A1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of ALDH5A1 mRNA PMID:22747577
12359249 NT5C1B 5'-nucleotidase, cytosolic IB gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NT5C1B mRNA PMID:38866337
12359367 MMP13 matrix metallopeptidase 13 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MMP13 mRNA PMID:38866337
12359874 ECHS1 enoyl-CoA hydratase, short chain 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of ECHS1 protein PMID:19952500
12359947 HCAR2 hydroxycarboxylic acid receptor 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HCAR2 mRNA PMID:38866337
12361015 SDHA succinate dehydrogenase complex flavoprotein subunit A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SDHA mRNA PMID:38866337
12361696 ID4 inhibitor of DNA binding 4, HLH protein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ID4 mRNA PMID:38866337
12362311 PPFIA1 PTPRF interacting protein alpha 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPFIA1 mRNA PMID:38866337
12362351 B9D2 B9 domain containing 2 gene CHEBI:17347 testosterone increases expression EXP E RGD:6480464 20191114 CTD MESH:D013739 Testosterone results in increased expression of TGFB1 mRNA PMID:17157324
12362351 B9D2 B9 domain containing 2 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of TGFB1 mRNA; ochratoxin A results in increased expression of TGFB1 protein PMID:33543323
12362351 B9D2 B9 domain containing 2 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of TGFB1 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 protein] PMID:33543323
12362545 DYNC2H1 dynein cytoplasmic 2 heavy chain 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DYNC2H1 mRNA PMID:38866337
12362811 CAMK2G calcium/calmodulin dependent protein kinase II gamma gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CAMK2G mRNA PMID:22747577
12362885 STYXL1 serine/threonine/tyrosine interacting like 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of STYXL1 mRNA PMID:22747577
12363067 IL1RL1 interleukin 1 receptor like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of IL1RL1 mRNA PMID:38866337
12363226 LEPR leptin receptor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LEPR mRNA PMID:38866337
12363261 FGL1 fibrinogen like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FGL1 mRNA PMID:38866337
12363516 TNFRSF21 TNF receptor superfamily member 21 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TNFRSF21 mRNA PMID:38866337
12364239 NLRP3 NLR family pyrin domain containing 3 gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of NLRP3 mRNA; ochratoxin A results in increased expression of NLRP3 protein PMID:33543323
12364239 NLRP3 NLR family pyrin domain containing 3 gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of NLRP3 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of ACTA2 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of CASP1 mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of GSDMD mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of GSDMD protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of IL18 mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of IL1B mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of PYCARD mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of PYCARD protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of TGFB1 protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of VIM protein] PMID:33543323
12364261 SPATA20 spermatogenesis associated 20 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SPATA20 mRNA PMID:38866337
12364501 YIF1A Yip1 interacting factor homolog A, membrane trafficking protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of YIF1A mRNA PMID:38866337
12364607 ABCB4 ATP binding cassette subfamily B member 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ABCB4 mRNA PMID:38866337
12364716 SEC16B SEC16 homolog B, endoplasmic reticulum export factor gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SEC16B mRNA PMID:38866337
12365019 DMXL2 Dmx like 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DMXL2 mRNA PMID:38866337
12365506 ADRB1 adrenoceptor beta 1 gene CHEBI:135359 denopamine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C037293 denopamine binds to and results in increased activity of ADRB1 protein PMID:3831029
12365506 ADRB1 adrenoceptor beta 1 gene CHEBI:135592 amosulalol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C032473 amosulalol binds to and results in decreased activity of ADRB1 protein PMID:6129981
12365506 ADRB1 adrenoceptor beta 1 gene CHEBI:18357 (R)-noradrenaline increases activity EXP E RGD:6480464 20191114 CTD MESH:D009638 Norepinephrine results in increased activity of ADRB1 protein PMID:10344530
12365509 STING1 stimulator of interferon response cGAMP interactor 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of TMEM173 mRNA PMID:22747577
12365935 KLK6 kallikrein related peptidase 6 gene CHEBI:31516 Doramectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C084101 ABCB1 gene mutant form affects the reaction [doramectin affects the expression of KLK6 mRNA] PMID:25419811
12365935 KLK6 kallikrein related peptidase 6 gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of KLK6 mRNA] PMID:25419811
12365935 KLK6 kallikrein related peptidase 6 gene CHEBI:50345 milbemycin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C027837 ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of KLK6 mRNA] PMID:25419811
12365935 KLK6 kallikrein related peptidase 6 gene CHEBI:6078 ivermectin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007559 ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of KLK6 mRNA] PMID:25419811
12366252 ZSCAN22 zinc finger and SCAN domain containing 22 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZSCAN22 mRNA PMID:38866337
12366564 ANKRD26 ankyrin repeat domain containing 26 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ANKRD26 mRNA PMID:22747577
12366895 LST1 leukocyte specific transcript 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LST1 mRNA PMID:38866337
12366906 POLE2 DNA polymerase epsilon 2, accessory subunit gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of DNAAF2 mRNA PMID:27255383
12367082 SMIM2 small integral membrane protein 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SMIM2 mRNA PMID:38866337
12367266 OGT O-linked N-acetylglucosamine (GlcNAc) transferase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of OGT mRNA PMID:22747577
12367467 MPLKIP M-phase specific PLK1 interacting protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MPLKIP mRNA PMID:38866337
12367920 ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ENTPD3 mRNA PMID:38866337
12367954 DUSP14 dual specificity phosphatase 14 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DUSP14 mRNA PMID:38866337
12368635 PTH parathyroid hormone gene CHEBI:31801 Maxacalcitol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C051883 maxacalcitol results in decreased expression of PTH protein PMID:10027919
12368635 PTH parathyroid hormone gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PTH mRNA PMID:22747577
12368850 SSR3 signal sequence receptor subunit 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SSR3 mRNA PMID:38866337
12369170 NONO non-POU domain containing octamer binding gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NONO mRNA PMID:38866337
12370052 PCSK1 proprotein convertase subtilisin/kexin type 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PCSK1 mRNA PMID:38866337
12370161 INS insulin gene CHEBI:17234 glucose decreases abundance EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein results in decreased abundance of Glucose PMID:1646414
12370161 INS insulin gene CHEBI:17234 glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 [INS protein co-treated with Glucose] results in decreased abundance of Potassium; [INS protein co-treated with Glucose] results in increased susceptibility to Digoxin; [INS protein co-treated with Glucose] results in increased uptake of Digoxin PMID:1013176|PMID:140932
12370161 INS insulin gene CHEBI:17634 D-glucose decreases abundance EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein results in decreased abundance of Glucose PMID:1646414
12370161 INS insulin gene CHEBI:17634 D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 [INS protein co-treated with Glucose] results in decreased abundance of Potassium; [INS protein co-treated with Glucose] results in increased susceptibility to Digoxin; [INS protein co-treated with Glucose] results in increased uptake of Digoxin PMID:1013176|PMID:140932
12370161 INS insulin gene CHEBI:17650 cortisol affects abundance EXP E RGD:6480464 20191114 CTD MESH:D006854 INS protein affects the abundance of Hydrocortisone PMID:1324617
12370161 INS insulin gene CHEBI:17650 cortisol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006854 Sodium affects the reaction [INS protein affects the abundance of Hydrocortisone] PMID:1324617
12370161 INS insulin gene CHEBI:26216 potassium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011188 [INS protein co-treated with Glucose] results in decreased abundance of Potassium PMID:1013176|PMID:140932
12370161 INS insulin gene CHEBI:26708 sodium atom affects response to substance EXP E RGD:6480464 20191114 CTD MESH:D012964 INS protein affects the susceptibility to Sodium PMID:1324617
12370161 INS insulin gene CHEBI:26708 sodium atom multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012964 INS protein promotes the reaction [Sodium results in increased abundance of Vasopressins]; Sodium affects the reaction [INS protein affects the abundance of Hydrocortisone] PMID:1324617
12370161 INS insulin gene CHEBI:31429 colforsin daropate hydrochloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005576 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein PMID:12639917
12370161 INS insulin gene CHEBI:37537 phorbol 13-acetate 12-myristate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013755 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK3 protein PMID:12639917
12370161 INS insulin gene CHEBI:3892 corticotropin increases abundance EXP E RGD:6480464 20191114 CTD MESH:D000324 INS protein results in increased abundance of Adrenocorticotropic Hormone PMID:1646414
12370161 INS insulin gene CHEBI:42758 aldehydo-D-glucose decreases abundance EXP E RGD:6480464 20191114 CTD MESH:D005947 INS protein results in decreased abundance of Glucose PMID:1646414
12370161 INS insulin gene CHEBI:42758 aldehydo-D-glucose multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005947 [INS protein co-treated with Glucose] results in decreased abundance of Potassium; [INS protein co-treated with Glucose] results in increased susceptibility to Digoxin; [INS protein co-treated with Glucose] results in increased uptake of Digoxin PMID:1013176|PMID:140932
12370161 INS insulin gene CHEBI:4551 digoxin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004077 [INS protein co-treated with Glucose] results in increased susceptibility to Digoxin; [INS protein co-treated with Glucose] results in increased uptake of Digoxin PMID:1013176|PMID:140932
12370161 INS insulin gene CHEBI:9937 vasopressin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014667 INS protein promotes the reaction [Sodium results in increased abundance of Vasopressins] PMID:1324617
12370168 ABHD14A abhydrolase domain containing 14A gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of ABHD14A mRNA PMID:22747577
12370207 LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of LAMTOR1 mRNA PMID:27255383
12370899 AOPEP aminopeptidase O (putative) gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AOPEP mRNA PMID:38866337
12371390 VDAC2 voltage dependent anion channel 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of VDAC2 mRNA PMID:38866337
12371781 ECHDC2 enoyl-CoA hydratase domain containing 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ECHDC2 mRNA PMID:38866337
12372035 TMEM210 transmembrane protein 210 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM210 mRNA PMID:38866337
12372333 TMEM200B transmembrane protein 200B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM200B mRNA PMID:38866337
12372342 RNASET2 ribonuclease T2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RNASET2 mRNA PMID:38866337
12372577 PCOLCE2 procollagen C-endopeptidase enhancer 2 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of PCOLCE2 mRNA PMID:22747577
12372593 HSPA8 heat shock protein family A (Hsp70) member 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HSPA8 mRNA PMID:38866337
12372707 PKP2 plakophilin 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PKP2 mRNA PMID:38866337
12372873 DES desmin gene CHEBI:3011 benazepril decreases expression EXP E RGD:6480464 20191114 CTD MESH:C044946 benazepril results in decreased expression of DES mRNA PMID:20137276
12372946 OR5AN1 olfactory receptor family 5 subfamily AN member 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of OR5AN1 mRNA PMID:38866337
12373160 TNF tumor necrosis factor gene CHEBI:132230 marbofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:C080260 marbofloxacin results in increased expression of TNF mRNA; marbofloxacin results in increased expression of TNF protein PMID:31005593
12373160 TNF tumor necrosis factor gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20220405 CTD MESH:D008070 Lipopolysaccharides results in increased expression of TNF mRNA PMID:32899721
12373160 TNF tumor necrosis factor gene CHEBI:16412 lipopolysaccharide multiple interactions EXP E RGD:6480464 20220405 CTD MESH:D008070 arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] PMID:32899721
12373160 TNF tumor necrosis factor gene CHEBI:26523 reactive oxygen species increases abundance EXP E RGD:6480464 20191114 CTD MESH:D017382 TNF protein results in increased abundance of Reactive Oxygen Species PMID:14973143
12373160 TNF tumor necrosis factor gene CHEBI:26523 reactive oxygen species multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D017382 manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; Vitamin E inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species] PMID:14973143
12373160 TNF tumor necrosis factor gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20191114 CTD MESH:D000666 Amphotericin B results in increased expression of TNF protein PMID:24105867
12373160 TNF tumor necrosis factor gene CHEBI:29866 arsenite(3-) multiple interactions EXP E RGD:6480464 20220405 CTD MESH:C015001 arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; HSP70 protein affects the reaction [arsenite inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] PMID:32899721
12373160 TNF tumor necrosis factor gene CHEBI:33234 vitamin E multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D024502 Vitamin E inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species] PMID:14973143
12373160 TNF tumor necrosis factor gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of TNF mRNA PMID:33543323
12373160 TNF tumor necrosis factor gene CHEBI:7719 ochratoxin A increases secretion EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased secretion of TNF protein PMID:33543323
12373160 TNF tumor necrosis factor gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of TNF mRNA; Ofloxacin results in increased expression of TNF protein PMID:24582689
12373344 BSDC1 BSD domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of BSDC1 mRNA PMID:38866337
12373359 MAGEF1 MAGE family member F1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of MAGEF1 mRNA PMID:22747577
12373364 ADRA2C adrenoceptor alpha 2C gene CHEBI:3757 clonidine (imino form) increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D003000 ADRA2C protein results in increased susceptibility to Clonidine PMID:16814767
12373364 ADRA2C adrenoceptor alpha 2C gene CHEBI:46631 clonidine increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D003000 ADRA2C protein results in increased susceptibility to Clonidine PMID:16814767
12373364 ADRA2C adrenoceptor alpha 2C gene CHEBI:46632 clonidine (amino form) increases response to substance EXP E RGD:6480464 20191114 CTD MESH:D003000 ADRA2C protein results in increased susceptibility to Clonidine PMID:16814767
12373533 MTURN maturin, neural progenitor differentiation regulator homolog gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MTURN mRNA PMID:38866337
12374086 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene CHEBI:26710 sodium chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased expression of JUN protein PMID:23816505
12374086 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 pyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]; U 0126 inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]] PMID:23816505
12374086 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of JUN mRNA PMID:22747577
12374086 JUN Jun proto-oncogene, AP-1 transcription factor subunit gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]] PMID:23816505
12374436 TACC3 transforming acidic coiled-coil containing protein 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TACC3 mRNA PMID:38866337
12374616 ADGRG4 adhesion G protein-coupled receptor G4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ADGRG4 mRNA PMID:38866337
12375274 NEK9 NIMA related kinase 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NEK9 mRNA PMID:38866337
12376416 VWA5A von Willebrand factor A domain containing 5A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of VWA5A mRNA PMID:38866337
12377078 JAK1 Janus kinase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of JAK1 mRNA PMID:38866337
12377146 S100A10 S100 calcium binding protein A10 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of S100A10 mRNA PMID:38866337
12377183 TPI1 triosephosphate isomerase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TPI1 mRNA PMID:38866337
12377502 IGFBP7 insulin like growth factor binding protein 7 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of IGFBP7 mRNA PMID:22747577
12377511 RAB27A RAB27A, member RAS oncogene family gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of RAB27A mRNA PMID:27255383
12377537 FANK1 fibronectin type III and ankyrin repeat domains 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FANK1 mRNA PMID:38866337
12377712 SYTL4 synaptotagmin like 4 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SYTL4 mRNA PMID:27255383
12377761 CLDN4 claudin 4 gene CHEBI:15367 all-trans-retinoic acid increases expression EXP E RGD:6480464 20191114 CTD MESH:D014212 Tretinoin results in increased expression of CLDN4 mRNA; Tretinoin results in increased expression of CLDN4 protein PMID:17035595
12377761 CLDN4 claudin 4 gene CHEBI:15367 all-trans-retinoic acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D014212 CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN4 mRNA] PMID:17035595
12377761 CLDN4 claudin 4 gene CHEBI:16199 urea increases expression EXP E RGD:6480464 20191114 CTD MESH:D014508 Urea results in increased expression of CLDN4 protein PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:16240 hydrogen peroxide increases expression EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased expression of CLDN4 protein PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein] PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005978 Glutathione inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:16899 D-mannitol increases expression EXP E RGD:6480464 20191114 CTD MESH:D008353 Mannitol results in increased expression of CLDN4 protein PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:26710 sodium chloride increases expression EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased expression of CLDN4 protein PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; diphenyleneiodonium inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:77986 dibenziodolium multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C007517 diphenyleneiodonium inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] PMID:23816505
12377761 CLDN4 claudin 4 gene CHEBI:90695 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C432165 pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] PMID:23816505
12377803 EDN1 endothelin 1 gene CHEBI:28790 serotonin increases activity EXP E RGD:6480464 20191114 CTD MESH:D012701 Serotonin results in increased activity of EDN1 protein PMID:9918753
12377803 EDN1 endothelin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of EDN1 mRNA PMID:38866337
12377803 EDN1 endothelin 1 gene CHEBI:5000 fenfluramine increases activity EXP E RGD:6480464 20191114 CTD MESH:D005277 Fenfluramine results in increased activity of EDN1 protein PMID:9918753
12377803 EDN1 endothelin 1 gene CHEBI:88212 lead(II) chloride increases secretion EXP E RGD:6480464 20191114 CTD MESH:C029891 lead chloride results in increased secretion of EDN1 protein PMID:15915659
12377973 CILK1 ciliogenesis associated kinase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CILK1 mRNA PMID:38866337
12378776 AKIRIN1 akirin 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AKIRIN1 mRNA PMID:38866337
12379410 OCRL OCRL inositol polyphosphate-5-phosphatase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of OCRL mRNA PMID:38866337
12379440 TSLP thymic stromal lymphopoietin gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of TSLP promoter PMID:33763461
12379440 TSLP thymic stromal lymphopoietin gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] results in increased methylation of TSLP promoter PMID:33763461
12379903 TTC9C tetratricopeptide repeat domain 9C gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TTC9C mRNA PMID:38866337
12379972 FBLL1 fibrillarin like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FBLL1 mRNA PMID:38866337
12380597 GATA4 GATA binding protein 4 gene CHEBI:4784 enalapril multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D004656 [Ranolazine co-treated with Enalapril] affects the expression of GATA4 protein PMID:18820026
12380597 GATA4 GATA binding protein 4 gene CHEBI:6904 metoprolol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008790 [Ranolazine co-treated with Metoprolol] affects the expression of GATA4 protein PMID:18820026
12380597 GATA4 GATA binding protein 4 gene CHEBI:87681 ranolazine affects expression EXP E RGD:6480464 20191114 CTD MESH:D000069458 Ranolazine affects the expression of GATA4 protein PMID:18820026
12380597 GATA4 GATA binding protein 4 gene CHEBI:87681 ranolazine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000069458 [Ranolazine co-treated with Enalapril] affects the expression of GATA4 protein; [Ranolazine co-treated with Metoprolol] affects the expression of GATA4 protein PMID:18820026
12380628 GOT1 glutamic-oxaloacetic transaminase 1 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of GOT1 protein PMID:19952500
12380628 GOT1 glutamic-oxaloacetic transaminase 1 gene CHEBI:9728 trimethaphan increases expression EXP E RGD:6480464 20191114 CTD MESH:D014294 Trimethaphan results in increased expression of GOT1 protein PMID:6848019
12380902 MPDZ multiple PDZ domain crumbs cell polarity complex component gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of MPDZ mRNA PMID:22747577
12381371 TNS1 tensin 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of TNS1 mRNA PMID:22747577
12381808 ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ALKBH2 mRNA PMID:38866337
12382389 UBE2C ubiquitin conjugating enzyme E2 C gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of UBE2C mRNA PMID:38866337
12383542 DPCD deleted in primary ciliary dyskinesia homolog gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of DPCD mRNA PMID:22747577
12383562 SERPINI1 serpin family I member 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SERPINI1 mRNA PMID:38866337
12383928 CYP2J2 cytochrome P450 family 2 subfamily J member 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CYP2J2 mRNA PMID:38866337
12384201 GSTA4 glutathione S-transferase alpha 4 gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of GSTA4 mRNA PMID:19952500
12384201 GSTA4 glutathione S-transferase alpha 4 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of GSTA4 mRNA PMID:22747577
12384201 GSTA4 glutathione S-transferase alpha 4 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of GSTA4 mRNA PMID:19952500
12384502 LONRF3 LON peptidase N-terminal domain and ring finger 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LONRF3 mRNA PMID:38866337
12384859 DCLK1 doublecortin like kinase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of DCLK1 mRNA PMID:38866337
12385838 GMFB glia maturation factor beta gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of GMFB mRNA PMID:22747577
12386265 CENPS centromere protein S gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CENPS mRNA PMID:38866337
12386575 MIR23B microRNA mir-23b gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR23B PMID:40036580
12386603 MGRH mas-related G-protein coupled receptor member X2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MGRH mRNA PMID:38866337
12386935 SPRY2 sprouty RTK signaling antagonist 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SPRY2 mRNA PMID:38866337
12387252 SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SULT1A1 mRNA PMID:38866337
12387389 KLHL12 kelch like family member 12 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KLHL12 mRNA PMID:38866337
12387446 RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RALGPS2 mRNA PMID:38866337
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16240 hydrogen peroxide increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D006861 Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein PMID:23816505
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16240 hydrogen peroxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D006861 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] PMID:23816505
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:16856 glutathione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005978 Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein] PMID:23816505
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:17924 D-glucitol increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D013012 Sorbitol results in increased phosphorylation of MAPK3 protein PMID:12639917
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:26710 sodium chloride increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D012965 Sodium Chloride results in increased phosphorylation of MAPK3 protein PMID:23816505
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:26710 sodium chloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D012965 Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein] PMID:23816505
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:27563 arsenic atom increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D001151 Arsenic results in increased phosphorylation of MAPK3 protein PMID:29306782
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:28939 N-acetyl-L-cysteine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D000111 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein] PMID:23816505
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:30621 diarsenic trioxide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C006632 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein PMID:23236503
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:31429 colforsin daropate hydrochloride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005576 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein PMID:12639917
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:37537 phorbol 13-acetate 12-myristate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013755 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK3 protein PMID:12639917
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:47217 arsane increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D001151 Arsenic results in increased phosphorylation of MAPK3 protein PMID:29306782
12388002 MAPK3 mitogen-activated protein kinase 3 gene CHEBI:49900 arsenous acid multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C032793 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK3 protein PMID:23236503
12388118 TNFRSF1A TNF receptor superfamily member 1A gene CHEBI:132230 marbofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:C080260 marbofloxacin results in increased expression of TNFRSF1A mRNA; marbofloxacin results in increased expression of TNFRSF1A protein PMID:31005593
12388118 TNFRSF1A TNF receptor superfamily member 1A gene CHEBI:132230 marbofloxacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C080260 TNFRSF1A mRNA promotes the reaction [marbofloxacin results in increased expression of CASP8 mRNA]; TNFRSF1A mRNA promotes the reaction [marbofloxacin results in increased expression of TRADD mRNA] PMID:31005593
12388118 TNFRSF1A TNF receptor superfamily member 1A gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of TNFRSF1A mRNA; Ofloxacin results in increased expression of TNFRSF1A protein PMID:24582689
12388118 TNFRSF1A TNF receptor superfamily member 1A gene CHEBI:7731 ofloxacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015242 TNFRSF1A mutant form inhibits the reaction [Ofloxacin results in increased expression of CASP8 mRNA]; TNFRSF1A mutant form inhibits the reaction [Ofloxacin results in increased expression of TRADD mRNA] PMID:24582689
12388250 OXCT1 3-oxoacid CoA-transferase 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of OXCT1 protein PMID:22747577
12388284 VPS13B vacuolar protein sorting 13 homolog B gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS13B mRNA PMID:27255383
12388284 VPS13B vacuolar protein sorting 13 homolog B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of VPS13B mRNA PMID:38866337
12388437 HEPHL1 hephaestin like 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HEPHL1 mRNA PMID:38866337
12388955 ARMH4 armadillo like helical domain containing 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ARMH4 mRNA PMID:38866337
12389147 TMTC1 transmembrane O-mannosyltransferase targeting cadherins 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMTC1 mRNA PMID:38866337
12389213 NPNT nephronectin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NPNT mRNA PMID:38866337
12389759 CBY1 chibby 1, beta catenin antagonist gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of CBY1 mRNA PMID:27255383
12390306 EMC9 ER membrane protein complex subunit 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EMC9 mRNA PMID:38866337
12390665 FFAR3 free fatty acid receptor 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FFAR3 mRNA PMID:38866337
12390722 FXYD4 FXYD domain containing ion transport regulator 4 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FXYD4 mRNA PMID:38866337
12391059 SRSF5 serine and arginine rich splicing factor 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SRSF5 mRNA PMID:38866337
12391828 SLC22A5 solute carrier family 22 member 5 gene CHEBI:38000 uniconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C092705 uniconazole results in decreased activity of SLC22A5 protein PMID:36669674
12391828 SLC22A5 solute carrier family 22 member 5 gene CHEBI:81781 tebuconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087114 tebuconazole results in decreased activity of SLC22A5 protein PMID:36669674
12391828 SLC22A5 solute carrier family 22 member 5 gene CHEBI:81970 penconazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C087058 penconazole results in decreased activity of SLC22A5 protein PMID:36669674
12391828 SLC22A5 solute carrier family 22 member 5 gene CHEBI:81980 triticonazole decreases activity EXP E RGD:6480464 20230801 CTD MESH:C412303 triticonazole results in decreased activity of SLC22A5 protein PMID:36669674
12391987 BAX BCL2 associated X, apoptosis regulator gene CHEBI:192461 toosendanin increases expression EXP E RGD:6480464 20240604 CTD MESH:C036454 toosendanin results in increased expression of BAX mRNA; toosendanin results in increased expression of BAX protein PMID:36809669
12391987 BAX BCL2 associated X, apoptosis regulator gene CHEBI:9241 spironolactone decreases expression EXP E RGD:6480464 20191114 CTD MESH:D013148 Spironolactone results in decreased expression of BAX protein PMID:20082611
12392076 BTBD3 BTB domain containing 3 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of BTBD3 mRNA PMID:22747577
12392149 LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of LAMTOR2 mRNA PMID:27255383
12392198 RAB44 RAB44, member RAS oncogene family gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of RAB44 mRNA PMID:22747577
12392574 SEC63 SEC63 homolog, protein translocation regulator gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SEC63 mRNA PMID:27255383
12392663 SEMA3C semaphorin 3C gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of SEMA3C mRNA PMID:38866337
12393385 GOLIM4 golgi integral membrane protein 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GOLIM4 mRNA PMID:38866337
12393411 AP3M2 adaptor related protein complex 3 subunit mu 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of AP3M2 mRNA PMID:38866337
12393596 UQCRC1 ubiquinol-cytochrome c reductase core protein 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of UQCRC1 protein PMID:19952500
12394086 GREM1 gremlin 1, DAN family BMP antagonist gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of GREM1 mRNA PMID:38866337
12395545 CFAP53 cilia and flagella associated protein 53 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CFAP53 mRNA PMID:38866337
12395639 ANGPT4 angiopoietin 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ANGPT4 mRNA PMID:38866337
12395891 UPP1 uridine phosphorylase 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of UPP1 mRNA PMID:38866337
12396172 MAOA monoamine oxidase A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAOA mRNA PMID:38866337
12396546 WDR82 WD repeat domain 82 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of WDR82 mRNA PMID:38866337
12396796 IL11 interleukin 11 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of IL11 mRNA PMID:38866337
12397246 DENND2A DENN domain containing 2A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DENND2A mRNA PMID:38866337
12398122 C7 complement C7 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of C7 mRNA PMID:38866337
12398527 AP2S1 adaptor related protein complex 2 subunit sigma 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of AP2S1 mRNA PMID:27255383
12398591 PRR14L proline rich 14 like gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PRR14L mRNA PMID:38866337
12398958 RIBC2 RIB43A domain with coiled-coils 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RIBC2 mRNA PMID:38866337
12398969 OOEP oocyte expressed protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of OOEP mRNA PMID:38866337
12398987 SLC22A3 solute carrier family 22 member 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC22A3 mRNA PMID:38866337
12399007 COPG1 COPI coat complex subunit gamma 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of COPG1 mRNA PMID:27255383
12399086 ENO3 enolase 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ENO3 mRNA PMID:38866337
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:10093 yohimbine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015016 Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; Yohimbine inhibits the reaction [Clonidine results in increased activity of PIK3CG protein] PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:18357 (R)-noradrenaline increases activity EXP E RGD:6480464 20191114 CTD MESH:D009638 Norepinephrine results in increased activity of PIK3CG protein PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:18357 (R)-noradrenaline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009638 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased activity of PIK3CG protein]; [Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:26034 phosphatidylinositol 3-phosphate multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C055525 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; [Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; [Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate] PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:3757 clonidine (imino form) increases activity EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in increased activity of PIK3CG protein PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:3757 clonidine (imino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 [Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; Yohimbine inhibits the reaction [Clonidine results in increased activity of PIK3CG protein] PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:46631 clonidine increases activity EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in increased activity of PIK3CG protein PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:46631 clonidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 [Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; Yohimbine inhibits the reaction [Clonidine results in increased activity of PIK3CG protein] PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:46632 clonidine (amino form) increases activity EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in increased activity of PIK3CG protein PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:46632 clonidine (amino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 [Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate; Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; Yohimbine inhibits the reaction [Clonidine results in increased activity of PIK3CG protein] PMID:15958164
12399201 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma gene CHEBI:65329 LY294002 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Norepinephrine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased activity of PIK3CG protein] PMID:15958164
12399632 HEXB hexosaminidase subunit beta gene CHEBI:133151 methyl beta-cyclodextrin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C108732 methyl-beta-cyclodextrin promotes the reaction [mastoparan results in increased secretion of HEXB protein] PMID:21671308
12399632 HEXB hexosaminidase subunit beta gene CHEBI:199449 YM-254890 multiple interactions EXP E RGD:6480464 20231219 CTD MESH:C475455 YM-254890 inhibits the reaction [mastoparan results in increased secretion of HEXB protein] PMID:21671308
12399632 HEXB hexosaminidase subunit beta gene CHEBI:49662 indometacin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D007213 Indomethacin promotes the reaction [mastoparan results in increased secretion of HEXB protein] PMID:21671308
12399632 HEXB hexosaminidase subunit beta gene CHEBI:61048 ganglioside GM1 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D005677 G(M1) Ganglioside inhibits the reaction [mastoparan results in increased secretion of HEXB protein]; G(M1) Ganglioside inhibits the reaction [Melitten results in increased secretion of HEXB protein]; G(M1) Ganglioside inhibits the reaction [Wasp Venoms results in increased secretion of HEXB protein] PMID:21334356|PMID:21671308
12399632 HEXB hexosaminidase subunit beta gene CHEBI:6736 melittin increases secretion EXP E RGD:6480464 20191114 CTD MESH:D008555 Melitten results in increased secretion of HEXB protein PMID:21334356
12399632 HEXB hexosaminidase subunit beta gene CHEBI:6736 melittin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D008555 G(M1) Ganglioside inhibits the reaction [Melitten results in increased secretion of HEXB protein]; sialogangliosides inhibits the reaction [Melitten results in increased secretion of HEXB protein]; trisialoganglioside GT1 inhibits the reaction [Melitten results in increased secretion of HEXB protein] PMID:21334356
12399632 HEXB hexosaminidase subunit beta gene CHEBI:78496 mastoparan increases secretion EXP E RGD:6480464 20191114 CTD MESH:C037500 mastoparan results in increased secretion of HEXB protein PMID:21671308
12399632 HEXB hexosaminidase subunit beta gene CHEBI:78496 mastoparan multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C037500 G(M1) Ganglioside inhibits the reaction [mastoparan results in increased secretion of HEXB protein]; ganglioside, GD1a inhibits the reaction [mastoparan results in increased secretion of HEXB protein]; Indomethacin promotes the reaction [mastoparan results in increased secretion of HEXB protein]; methyl-beta-cyclodextrin promotes the reaction [mastoparan results in increased secretion of HEXB protein]; Pertussis Toxin inhibits the reaction [mastoparan results in increased secretion of HEXB protein]; Quinacrine promotes the reaction [mastoparan results in increased secretion of HEXB protein]; YM-254890 inhibits the reaction [mastoparan results in increased secretion of HEXB protein] PMID:21671308
12399632 HEXB hexosaminidase subunit beta gene CHEBI:8711 quinacrine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D011796 Quinacrine promotes the reaction [mastoparan results in increased secretion of HEXB protein] PMID:21671308
12399725 SYCE2 synaptonemal complex central element protein 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SYCE2 mRNA PMID:38866337
12400151 VPS52 VPS52 subunit of GARP complex gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS52 mRNA PMID:27255383
12400632 CD109 CD109 molecule gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CD109 mRNA PMID:38866337
12401213 BNIP1 BCL2 interacting protein 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of BNIP1 mRNA PMID:27255383
12401729 PLAGL1 PLAG1 like zinc finger 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PLAGL1 mRNA PMID:38866337
12401795 HNF4A hepatocyte nuclear factor 4 alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HNF4A mRNA PMID:38866337
12402016 COX19 cytochrome c oxidase assembly factor COX19 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of COX19 mRNA PMID:38866337
12402277 SULF2 sulfatase 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SULF2 mRNA PMID:38866337
12402328 GPR137B G protein-coupled receptor 137B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of GPR137B mRNA PMID:38866337
12402361 CLCC1 chloride channel CLIC like 1 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CLCC1 mRNA PMID:38866337
12402456 CA3 carbonic anhydrase 3 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of CA3 protein PMID:19952500
12402575 INO80C INO80 complex subunit C gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of INO80C mRNA PMID:38866337
12403052 FBXW12 F-box and WD repeat domain containing 12 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FBXW12 mRNA PMID:38866337
12403252 GSDMD gasdermin D gene CHEBI:7719 ochratoxin A increases expression EXP E RGD:6480464 20210608 CTD MESH:C025589 ochratoxin A results in increased expression of GSDMD mRNA; ochratoxin A results in increased expression of GSDMD protein PMID:33543323
12403252 GSDMD gasdermin D gene CHEBI:7719 ochratoxin A multiple interactions EXP E RGD:6480464 20210608 CTD MESH:C025589 CASP1 protein affects the reaction [ochratoxin A results in increased expression of GSDMD mRNA]; CASP1 protein affects the reaction [ochratoxin A results in increased expression of GSDMD protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of GSDMD mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of GSDMD mRNA]; NLRP3 protein affects the reaction [ochratoxin A results in increased expression of GSDMD protein] PMID:33543323
12403685 ME3 malic enzyme 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ME3 mRNA PMID:38866337
12403932 NDRG2 NDRG family member 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NDRG2 mRNA PMID:38866337
12404079 IL13 interleukin 13 gene CHEBI:15864 luteolin multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D047311 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA] PMID:33763461
12404079 IL13 interleukin 13 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of IL13 mRNA PMID:22747577
12404079 IL13 interleukin 13 gene CHEBI:69478 cannabidiol multiple interactions EXP E RGD:6480464 20211207 CTD MESH:D002185 [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL17 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of CCL2 mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of IL31RA mRNA]; [Cannabidiol co-treated with Luteolin co-treated with 3,3',4,5'-tetrahydroxystilbene] inhibits the reaction [[IL4 protein co-treated with IL13 protein co-treated with IL31 protein] results in increased expression of TSLP mRNA] PMID:33763461
12404196 CDADC1 cytidine and dCMP deaminase domain containing 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of CDADC1 mRNA PMID:22747577
12404336 KCTD19 potassium channel tetramerization domain containing 19 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of KCTD19 mRNA PMID:22747577
12404870 NCOR1 nuclear receptor corepressor 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NCOR1 mRNA PMID:38866337
12405277 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene CHEBI:16412 lipopolysaccharide increases expression EXP E RGD:6480464 20191114 CTD MESH:D008070 Lipopolysaccharides results in increased expression of HSD11B1 mRNA PMID:21798686
12405277 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 gene CHEBI:41879 dexamethasone increases expression EXP E RGD:6480464 20191114 CTD MESH:D003907 Dexamethasone results in increased expression of HSD11B1 mRNA PMID:21798686
12405409 CASP12 caspase 12 gene CHEBI:7731 ofloxacin increases expression EXP E RGD:6480464 20191114 CTD MESH:D015242 Ofloxacin results in increased expression of CASP12 mRNA; Ofloxacin results in increased expression of CASP12 protein PMID:24582689
12407878 OLFML1 olfactomedin like 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of OLFML1 mRNA PMID:38866337
12407942 KRT7 keratin 7 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of KRT7 mRNA PMID:38866337
12408217 DNAAF8 dynein axonemal assembly factor 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DNAAF8 mRNA PMID:38866337
12408234 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of RRAD mRNA PMID:38866337
12408957 HTR1B 5-hydroxytryptamine receptor 1B gene CHEBI:3374 capsaicin multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D002211 HTR1B protein promotes the reaction [donitriptan results in decreased susceptibility to Capsaicin] PMID:16880765
12408972 POLR3B RNA polymerase III subunit B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of POLR3B mRNA PMID:38866337
12409610 AGXT alanine--glyoxylate and serine--pyruvate aminotransferase gene CHEBI:3750 clofibrate decreases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in decreased expression of AGXT protein PMID:19952500
12409610 AGXT alanine--glyoxylate and serine--pyruvate aminotransferase gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of AGXT protein PMID:19952500
12409625 GADD45A growth arrest and DNA damage inducible alpha gene CHEBI:64090 tert-butyl hydroperoxide decreases expression EXP E RGD:6480464 20191114 CTD MESH:D020122 tert-Butylhydroperoxide results in decreased expression of GADD45A protein PMID:14729356
12409625 GADD45A growth arrest and DNA damage inducible alpha gene CHEBI:64090 tert-butyl hydroperoxide increases expression EXP E RGD:6480464 20191114 CTD MESH:D020122 tert-Butylhydroperoxide results in increased expression of GADD45A protein PMID:14729356
12409798 LOC477540 SEC14-like protein 3 gene CHEBI:8069 phenobarbital decreases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in decreased expression of SEC14L3 protein PMID:19952500
12409991 CDPF1 cysteine rich DPF motif domain containing 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CDPF1 mRNA PMID:38866337
12410105 MIR191 microRNA mir-191 gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR191 PMID:40036580
12410885 UTRN utrophin gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of UTRN mRNA PMID:38866337
12410985 HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HSD17B4 mRNA PMID:38866337
12411231 HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of HPS4 mRNA PMID:27255383
12412406 SLC44A1 solute carrier family 44 member 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SLC44A1 mRNA PMID:38866337
12412760 CD55 CD55 molecule gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of CD55 mRNA PMID:38866337
12413958 MIR30A microRNA mir-30a gene CHEBI:17833 gentamycin increases expression EXP E RGD:6480464 20210608 CTD MESH:D005839 Gentamicins results in increased expression of MIR30A mRNA PMID:33290828
12413958 MIR30A microRNA mir-30a gene CHEBI:2682 amphotericin B increases expression EXP E RGD:6480464 20250603 CTD MESH:D000666 Amphotericin B results in increased expression of MIR30A PMID:40036580
12414217 PRKCZ protein kinase C zeta gene CHEBI:10093 yohimbine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D015016 Yohimbine inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein] PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:18357 (R)-noradrenaline increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D009638 Norepinephrine results in increased phosphorylation of PRKCZ protein PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:18357 (R)-noradrenaline multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D009638 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased phosphorylation of PRKCZ protein] PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PRKCZ mRNA PMID:38866337
12414217 PRKCZ protein kinase C zeta gene CHEBI:3757 clonidine (imino form) increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in increased phosphorylation of PRKCZ protein PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:3757 clonidine (imino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein]; Yohimbine inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein] PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:46631 clonidine increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in increased phosphorylation of PRKCZ protein PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:46631 clonidine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein]; Yohimbine inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein] PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:46632 clonidine (amino form) increases phosphorylation EXP E RGD:6480464 20191114 CTD MESH:D003000 Clonidine results in increased phosphorylation of PRKCZ protein PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:46632 clonidine (amino form) multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D003000 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein]; Yohimbine inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein] PMID:15958164
12414217 PRKCZ protein kinase C zeta gene CHEBI:65329 LY294002 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased phosphorylation of PRKCZ protein] PMID:15958164
12414289 DUSP6 dual specificity phosphatase 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DUSP6 mRNA PMID:38866337
12414357 EZR ezrin gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of EZR protein PMID:32991862
12414955 ADGRG6 adhesion G protein-coupled receptor G6 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ADGRG6 mRNA PMID:38866337
12415481 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of HERPUD1 mRNA PMID:22747577
12415572 LRP1 LDL receptor related protein 1 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of LRP1 mRNA PMID:22747577
12416162 TFRC transferrin receptor gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of TFRC mRNA PMID:27255383
12416191 PYGL glycogen phosphorylase L gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PYGL mRNA PMID:38866337
12416245 PDGFRA platelet derived growth factor receptor alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PDGFRA mRNA PMID:38866337
12416324 OGFOD2 2-oxoglutarate and iron dependent oxygenase domain containing 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of OGFOD2 mRNA PMID:38866337
12416750 ACP5 acid phosphatase 5, tartrate resistant gene CHEBI:27881 resveratrol multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C059514 Resveratrol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] PMID:21239502
12416923 RAB3IP RAB3A interacting protein gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of RAB3IP mRNA PMID:27255383
12417120 ARHGDIB Rho GDP dissociation inhibitor beta gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ARHGDIB mRNA PMID:38866337
12417286 ERO1A endoplasmic reticulum oxidoreductase 1 alpha gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of ERO1A mRNA PMID:38866337
12418326 PPM1J protein phosphatase, Mg2+/Mn2+ dependent 1J gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PPM1J mRNA PMID:38866337
12418463 ACACA acetyl-CoA carboxylase alpha gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ACACA mRNA PMID:38866337
12418710 FAM107A family with sequence similarity 107 member A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FAM107A mRNA PMID:38866337
12419758 SNX16 sorting nexin 16 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SNX16 mRNA PMID:27255383
12420162 ADIPOQ adiponectin, C1Q and collagen domain containing gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ADIPOQ mRNA PMID:38866337
12420356 KCNS3 potassium voltage-gated channel modifier subfamily S member 3 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of KCNS3 mRNA PMID:27255383
12420682 KLHL5 kelch like family member 5 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of KLHL5 mRNA PMID:22747577
12421372 LOC102151342 ATP synthase subunit d, mitochondrial-like gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in increased expression of ATP5PD protein PMID:32991862
12421480 KCNH2 potassium voltage-gated channel subfamily H member 2 gene CHEBI:2896 astemizole multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D016589 Astemizole binds to and results in decreased activity of KCNH2 protein PMID:12388285
12421480 KCNH2 potassium voltage-gated channel subfamily H member 2 gene CHEBI:3720 cisapride multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020117 Cisapride binds to and results in decreased activity of KCNH2 protein PMID:12388285
12421480 KCNH2 potassium voltage-gated channel subfamily H member 2 gene CHEBI:9453 Terfenadine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D016593 Terfenadine binds to and results in decreased activity of KCNH2 protein PMID:12388285
12421480 KCNH2 potassium voltage-gated channel subfamily H member 2 gene CHEBI:95129 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020117 Cisapride binds to and results in decreased activity of KCNH2 protein PMID:12388285
12421900 C1QTNF2 C1q and TNF related 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of C1QTNF2 mRNA PMID:38866337
12421987 BNIP3 BCL2 interacting protein 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of BNIP3 mRNA PMID:38866337
12421997 AIF1L allograft inflammatory factor 1 like gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of AIF1L mRNA PMID:38866337
12422242 TCP11 t-complex 11 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TCP11 mRNA PMID:38866337
12422763 PEBP4 phosphatidylethanolamine binding protein 4 gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of PEBP4 mRNA PMID:22747577
12423735 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of NDUFV3 mRNA PMID:38866337
12423746 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HMGCS1 mRNA PMID:38866337
12423997 FICD FIC domain protein adenylyltransferase gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of FICD mRNA PMID:38866337
12424322 CDH1 cadherin 1 gene CHEBI:138858 Azaspiracid decreases uptake EXP E RGD:6480464 20191114 CTD MESH:C406592 azaspiracid results in decreased uptake of CDH1 protein modified form PMID:20547569
12424596 OCA2 OCA2 melanosomal transmembrane protein gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of OCA2 mRNA PMID:22747577
12424884 TMCO2 transmembrane and coiled-coil domains 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of TMCO2 mRNA PMID:38866337
12425093 NRAS NRAS proto-oncogene, GTPase gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of NRAS mRNA PMID:22747577
12425104 FASLG Fas ligand gene CHEBI:3441 carvedilol decreases expression EXP E RGD:6480464 20191114 CTD MESH:C043211 Carvedilol results in decreased expression of FASLG PMID:12875697
12425341 NIN ninein gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NIN mRNA PMID:38866337
12425566 UBR1 ubiquitin protein ligase E3 component n-recognin 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of UBR1 mRNA PMID:38866337
12425628 BCHE butyrylcholinesterase gene CHEBI:136185 VX nerve agent decreases activity EXP E RGD:6480464 20191114 CTD MESH:C009680 VX-agent results in decreased activity of BCHE protein PMID:16915560
12425628 BCHE butyrylcholinesterase gene CHEBI:17941 diisopropyl fluorophosphate decreases activity EXP E RGD:6480464 20191114 CTD MESH:D007531 Isoflurophate results in decreased activity of BCHE protein PMID:4631366
12425628 BCHE butyrylcholinesterase gene CHEBI:196010 Butyrylcholine increases hydrolysis EXP E RGD:6480464 20231003 CTD MESH:C017100 BCHE protein results in increased hydrolysis of butyrylcholine PMID:4631366|PMID:4985882
12425628 BCHE butyrylcholinesterase gene CHEBI:196010 Butyrylcholine multiple interactions EXP E RGD:6480464 20231003 CTD MESH:C017100 Succinylcholine inhibits the reaction [BCHE protein results in increased hydrolysis of butyrylcholine] PMID:4985882
12425628 BCHE butyrylcholinesterase gene CHEBI:27827 paraoxon decreases activity EXP E RGD:6480464 20191114 CTD MESH:D010261 Paraoxon results in decreased activity of BCHE protein PMID:4631366
12425628 BCHE butyrylcholinesterase gene CHEBI:30336 phosphoryl trichloride decreases activity EXP E RGD:6480464 20191114 CTD MESH:C013196 phosphoryl chloride results in decreased activity of BCHE protein PMID:12641435
12425628 BCHE butyrylcholinesterase gene CHEBI:34690 dichlorvos decreases activity EXP E RGD:6480464 20191114 CTD MESH:D004006 Dichlorvos results in decreased activity of BCHE protein PMID:3627083|PMID:4631366
12425628 BCHE butyrylcholinesterase gene CHEBI:41055 butyrylthiocholine increases hydrolysis EXP E RGD:6480464 20191114 CTD MESH:D002092 BCHE protein results in increased hydrolysis of Butyrylthiocholine PMID:22407886
12425628 BCHE butyrylcholinesterase gene CHEBI:45652 succinylcholine increases hydrolysis EXP E RGD:6480464 20191114 CTD MESH:D013390 BCHE protein results in increased hydrolysis of Succinylcholine PMID:4985882
12425628 BCHE butyrylcholinesterase gene CHEBI:45652 succinylcholine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013390 Succinylcholine inhibits the reaction [BCHE protein results in increased hydrolysis of butyrylcholine] PMID:4985882
12425628 BCHE butyrylcholinesterase gene CHEBI:75701 sarin decreases activity EXP E RGD:6480464 20191114 CTD MESH:D012524 Sarin results in decreased activity of BCHE protein PMID:16915560
12425628 BCHE butyrylcholinesterase gene CHEBI:9195 Soman decreases activity EXP E RGD:6480464 20191114 CTD MESH:D012999 Soman results in decreased activity of BCHE protein PMID:16915560
12426390 TOGARAM1 TOG array regulator of axonemal microtubules 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TOGARAM1 mRNA PMID:38866337
12426825 HMGB3 high mobility group box 3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HMGB3 mRNA PMID:38866337
12427021 SPACA9 sperm acrosome associated 9 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of SPACA9 mRNA PMID:38866337
12427518 FBXO21 F-box protein 21 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of FBXO21 mRNA PMID:38866337
12427628 AP2M1 adaptor related protein complex 2 subunit mu 1 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of AP2M1 mRNA PMID:27255383
12427803 MBOAT2 membrane bound O-acyltransferase domain containing 2 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of MBOAT2 mRNA PMID:38866337
12428027 YIF1B Yip1 interacting factor homolog B, membrane trafficking protein gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of YIF1B mRNA PMID:38866337
12428330 EIF5B eukaryotic translation initiation factor 5B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of EIF5B mRNA PMID:38866337
12428363 CALU calumenin gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of CALU mRNA PMID:38866337
12428468 UGDH UDP-glucose 6-dehydrogenase gene CHEBI:8069 phenobarbital increases expression EXP E RGD:6480464 20191114 CTD MESH:D010634 Phenobarbital results in increased expression of UGDH protein PMID:19952500
12428650 ABCA8 ATP binding cassette subfamily A member 8 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ABCA8 mRNA PMID:38866337
12429094 NKX3-2 NK3 homeobox 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of NKX3-2 mRNA PMID:38866337
12429250 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D013749 [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12429250 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:28909 iprodione multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C033148 [iprodione binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12429250 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:63933 Aroclor 1254 multiple interactions EXP E RGD:6480464 20191114 CTD MESH:D020111 [Chlorodiphenyl (54% Chlorine) binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12429250 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:77013 beta-naphthoflavone increases activity EXP E RGD:6480464 20191114 CTD MESH:D019324 beta-Naphthoflavone results in increased activity of CYP1A1 protein PMID:3929785
12429250 CYP1A1 cytochrome P450 family 1 subfamily A member 1 gene CHEBI:8434 prochloraz multiple interactions EXP E RGD:6480464 20191114 CTD MESH:C045362 [prochloraz binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 protein PMID:24389113
12429473 HOXA3 homeobox A3 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of HOXA3 mRNA PMID:38866337
12429763 RAPGEF5 Rap guanine nucleotide exchange factor 5 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RAPGEF5 mRNA PMID:38866337
12429909 VPS35 VPS35 retromer complex component gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of VPS35 mRNA PMID:27255383
12430030 LRP12 LDL receptor related protein 12 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of LRP12 mRNA PMID:38866337
12430104 PRSS23 serine protease 23 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of PRSS23 mRNA PMID:38866337
12430377 PHKA1 phosphorylase kinase regulatory subunit alpha 1 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of PHKA1 mRNA PMID:38866337
12430908 RBM6 RNA binding motif protein 6 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of RBM6 mRNA PMID:38866337
12432663 ZC3H11A zinc finger CCCH-type containing 11A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ZC3H11A mRNA PMID:38866337
12432698 APLP2 amyloid beta precursor like protein 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of APLP2 mRNA PMID:38866337
12433306 HOMEZ homeobox and leucine zipper encoding gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of HOMEZ mRNA PMID:38866337
12433472 MAT2A methionine adenosyltransferase 2A gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of MAT2A mRNA PMID:38866337
12433672 TCP1 t-complex 1 gene CHEBI:63450 masitinib decreases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in decreased expression of TCP1 protein PMID:22747577
12435619 APOB apolipoprotein B gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of APOB mRNA PMID:38866337
12436414 HSPD1 heat shock protein family D (Hsp60) member 1 gene CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP E RGD:6480464 20210309 CTD MESH:D014527 Uric Acid results in decreased expression of HSPD1 protein PMID:32991862
12436414 HSPD1 heat shock protein family D (Hsp60) member 1 gene CHEBI:3750 clofibrate increases expression EXP E RGD:6480464 20191114 CTD MESH:D002994 Clofibrate results in increased expression of HSPD1 protein PMID:19952500
12436542 SNX7 sorting nexin 7 gene CHEBI:197437 mocetinostat increases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in increased expression of SNX7 mRNA PMID:27255383
13385227 POLR2L RNA polymerase II, I and III subunit L gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of POLR2L mRNA PMID:38866337
13395345 ADRA1D adrenoceptor alpha 1D gene CHEBI:31891 Naftopidil multiple interactions EXP E RGD:6480464 20210114 CTD MESH:C064357 naftopidil binds to and results in decreased activity of ADRA1D protein; naftopidil inhibits the reaction [Phenylephrine binds to and results in increased activity of ADRA1D protein] PMID:19371927
13395345 ADRA1D adrenoceptor alpha 1D gene CHEBI:8093 phenylephrine multiple interactions EXP E RGD:6480464 20210114 CTD MESH:D010656 BMY 7378 inhibits the reaction [Phenylephrine binds to and results in increased activity of ADRA1D protein]; naftopidil inhibits the reaction [Phenylephrine binds to and results in increased activity of ADRA1D protein]; Phenylephrine binds to and results in increased activity of ADRA1D protein PMID:19371927
40822741 OR5AN5P olfactory receptor family 5 subfamily AN member 5, pseudogene gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of OR5AN5P mRNA PMID:38866337
40911580 SCT secretin gene CHEBI:16684 atropine multiple interactions EXP E RGD:6480464 20210119 CTD MESH:D001285 Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] PMID:3562434
40911580 SCT secretin gene CHEBI:17544 hydrogencarbonate increases abundance EXP E RGD:6480464 20210119 CTD MESH:D001639 SCT protein results in increased abundance of Bicarbonates PMID:3562434
40911580 SCT secretin gene CHEBI:17544 hydrogencarbonate multiple interactions EXP E RGD:6480464 20210119 CTD MESH:D001639 [Ceruletide co-treated with SCT protein] results in increased abundance of Bicarbonates; Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] PMID:3562434
40911580 SCT secretin gene CHEBI:28358 rac-lactic acid decreases abundance EXP E RGD:6480464 20210119 CTD MESH:D019344 SCT protein results in decreased abundance of Lactic Acid PMID:2418308
40911580 SCT secretin gene CHEBI:59219 ceruletide multiple interactions EXP E RGD:6480464 20210119 CTD MESH:D002108 [Ceruletide co-treated with SCT protein] results in increased abundance of Bicarbonates PMID:3562434
40911580 SCT secretin gene CHEBI:78320 2-hydroxypropanoic acid decreases abundance EXP E RGD:6480464 20210119 CTD MESH:D019344 SCT protein results in decreased abundance of Lactic Acid PMID:2418308
40911580 SCT secretin gene CHEBI:78734 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP E RGD:6480464 20210119 CTD MESH:D001285 Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] PMID:3562434
40915058 ARNT aryl hydrocarbon receptor nuclear translocator gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of ARNT mRNA PMID:38866337
40915687 LMO2 LIM domain only 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of LMO2 mRNA PMID:38866337
40918198 C13H8orf82 chromosome 13 C8orf82 homolog gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of C13H8ORF82 mRNA PMID:38866337
40918519 KCTD7 potassium channel tetramerization domain containing 7 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of KCTD7 mRNA PMID:38866337
40919152 SRR serine racemase gene CHEBI:63450 masitinib increases expression EXP E RGD:6480464 20210608 CTD MESH:C526575 masitinib results in increased expression of SRR mRNA PMID:22747577
40922397 THOC3 THO complex subunit 3 gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of THOC3 mRNA PMID:38866337
40923260 C30H15orf48 chromosome 30 C15orf48 homolog gene CHEBI:33216 bisphenol A decreases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in decreased expression of C30H15ORF48 mRNA PMID:38866337
40923323 TMEM30B transmembrane protein 30B gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of TMEM30B mRNA PMID:38866337
40923536 DYNLT2 dynein light chain Tctex-type 2 gene CHEBI:33216 bisphenol A increases expression EXP E RGD:6480464 20250114 CTD MESH:C006780 bisphenol A results in increased expression of DYNLT2 mRNA PMID:38866337
40924379 STAM2 signal transducing adaptor molecule 2 gene CHEBI:197437 mocetinostat decreases expression EXP E RGD:6480464 20231107 CTD MESH:C523184 mocetinostat results in decreased expression of STAM2 mRNA PMID:27255383